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1 ld offer potential new therapies for CRSwNP (incurable disease).
2  development of castration-resistant PCa, an incurable disease.
3 hile avoiding overtreatment in patients with incurable disease.
4 ne-sensitive prostate cancer is currently an incurable disease.
5    Multiple myeloma is usually considered an incurable disease.
6 tive disease-modifying therapies, remains an incurable disease.
7 H) is a life-threatening and progressive yet incurable disease.
8  agents, opening new developments in a still-incurable disease.
9  leukemia (T-ALL) is an aggressive and often incurable disease.
10 astatic tumors that often translates into an incurable disease.
11  Idiopathic Pulmonary Fibrosis, a lethal and incurable disease.
12 linical studies to improve treatment of this incurable disease.
13 rapeutic application of ABE in the currently incurable disease.
14 apeutic approaches for the treatment of such incurable disease.
15 hibitors for the treatment of this presently incurable disease.
16 ovel therapeutic interventions to treat this incurable disease.
17 nd provide a novel approach to treating this incurable disease.
18 tional opportunity for the treatment of this incurable disease.
19  potential opportunity for treatment of this incurable disease.
20 hronic lymphocytic leukemia (CLL) remains an incurable disease.
21 TR mutations cause cystic fibrosis, a lethal incurable disease.
22 ose and patients often present with advanced incurable disease.
23 o the development of an indolent and largely incurable disease.
24 rgeted, and multiple myeloma (MM) remains an incurable disease.
25 er (SCLC) at advanced stage is considered an incurable disease.
26 therapeutic target for the treatment of this incurable disease.
27 utes a potential therapeutic target for this incurable disease.
28 r therapeutic intervention in this otherwise incurable disease.
29 bination therapies for the treatment of this incurable disease.
30 us cell cancer (ESCC) present with advanced, incurable disease.
31 rly drug development trials in children with incurable disease.
32         Metastatic melanoma remains a mostly incurable disease.
33  radiotherapy, making radioresistant CRPC an incurable disease.
34 vival time, myeloma continues to be a mostly incurable disease.
35 ise as a therapeutic strategy to combat this incurable disease.
36  novel therapeutic target for this currently incurable disease.
37 in the development of new therapies for this incurable disease.
38 etastases and new therapeutic avenues for an incurable disease.
39 y lead to more effective treatments for this incurable disease.
40                  Multiple myeloma remains an incurable disease.
41  screening are not precursors of advanced or incurable disease.
42 f failed apoptosis of B cells and remains an incurable disease.
43 on of metastatic ability leads to clinically incurable disease.
44                  Malignant gliomas remain an incurable disease.
45 eatic adenocarcinoma present with surgically incurable disease.
46 allogeneic cellular therapy for this largely incurable disease.
47 e patients who go on to develop progressive, incurable disease.
48 patients under cART makes HIV-1 infection an incurable disease.
49 d achieve improved outcome in this presently incurable disease.
50 e useful in the management of this presently incurable disease.
51 equired for the management of this otherwise incurable disease.
52 d outcomes for patients with this previously incurable disease.
53 le therapeutic option for patients with this incurable disease.
54 mantle cell lymphoma (MCL) remains a largely incurable disease.
55 hronic lymphocytic leukemia (CLL) remains an incurable disease.
56  a more effective treatment strategy in this incurable disease.
57  expansions are responsible for more than 30 incurable diseases.
58 hem a promising therapy for the treatment of incurable diseases.
59 ues of patients with a wide range of serious incurable diseases.
60 tial as a component of gene therapeutics for incurable diseases.
61 discoveries and new treatments targeting yet incurable diseases.
62  increasing because of their contribution in incurable diseases.
63  mycosis fungoides/Sezary syndrome, a set of incurable diseases.
64 to further clinical gains in these otherwise incurable diseases.
65 o offer unproven procedures to patients with incurable diseases.
66 peutic alternative for many debilitating and incurable diseases.
67 s to vaccination, implantation, and treating incurable diseases.
68 ous potential for clinical treatment of many incurable diseases.
69   Muscular dystrophies are common, currently incurable diseases.
70 ising therapeutic targets in these currently incurable diseases.
71 in advancing cures for a number of otherwise incurable diseases.
72 icity and dosing of potential treatments for incurable diseases.
73                                    It was an incurable disease 50 years ago, but approximately 70% of
74            Osteoarthritis (OA) is a painful, incurable disease affecting over 500 million people.
75    Alzheimer's dementia is a devastating and incurable disease afflicting over 35 million people worl
76  Pulmonary arterial hypertension (PAH) is an incurable disease, although symptoms are treated with a
77 east cancer has a high risk of recurrence to incurable disease and needs improved prognostic and ther
78      Recurrent breast cancer is typically an incurable disease and, as such, is disproportionately re
79 ondrial DNA (mtDNA) deletion mutations cause incurable diseases and contribute to aging, little is kn
80  (mtDNA) mutations are often associated with incurable diseases and lead to detectable pathogenic var
81 y common in prostate cancer (PCa), represent incurable disease, and are refractory to immunotherapy.
82                However MCL remains a largely incurable disease, and following relapse, it can be a ch
83                               WM is still an incurable disease, and patients succumb because of disea
84                  Multiple myeloma remains an incurable disease, and the cellular and molecular evolut
85               Lung cancer is still a largely incurable disease; annual lung-cancer mortality in women
86                             Lymphedema is an incurable disease associated with lymphatic dysfunction
87  leads to a typical clinical presentation of incurable disease at initial diagnosis.
88        Most patients diagnosed with EAC have incurable disease at the time of detection.
89  leads to a typical clinical presentation of incurable disease at the time of diagnosis.
90 t time, AML remains a devastating and mostly incurable disease, but the combination of optimized chem
91                    Friedreich's ataxia is an incurable disease caused by frataxin (FXN) protein defic
92 ystrophic epidermolysis bullosa (RDEB) is an incurable disease caused by mutations in the gene encodi
93 Ataxia Type 3 (SCA3), one of nine inherited, incurable diseases caused by similar mutations.
94  Pulmonary arterial hypertension (PAH) is an incurable disease characterized by a progressive increas
95     Chronic lymphocytic leukemia (CLL) is an incurable disease characterized by accumulation of clona
96 pinocerebellar ataxias (SCAs) are a class of incurable diseases characterized by degeneration of the
97                  Multiple myeloma remains an incurable disease, despite the development of numerous d
98                      HIV-1 causes a chronic, incurable disease due to its persistence in CD4+ T cells
99                 Furthermore, CLL is still an incurable disease due to the persistence of residual leu
100               Metastatic melanoma remains an incurable disease for many patients due to the limited s
101 recent advances, multiple myeloma remains an incurable disease for most patients, and initial remissi
102 on-small cell lung cancer (NSCLC) remains an incurable disease for most patients.
103          Mantle cell lymphoma is a generally incurable disease for which blood or marrow transplantat
104            Malignant mesothelioma remains an incurable disease for which immune-modulatory therapies,
105 etastatic prostate cancer largely remains an incurable disease, highlighting the need to better under
106 ic and induced) for regenerative medicine of incurable diseases, immunotherapy and blood transfusions
107 ioblastoma multiforme (GBM) remains a mainly incurable disease in desperate need of more effective tr
108    Amyloidoses are devastating and currently incurable diseases in which the process of amyloid forma
109               HIV/AIDS remains a chronic and incurable disease, in spite of the notable successes of
110 re toxic, causing or contributing to severe, incurable diseases including Alzheimer's and prion disea
111 mation of amyloid fibrils is associated with incurable diseases including Alzheimer's, Parkinson's, a
112 sfolded proteins are the hallmark of several incurable diseases, including Alzheimer's disease, type-
113 t stem cell replication and cause a range of incurable diseases, including dyskeratosis congenita (DC
114              For some patients with hitherto incurable diseases, including metastatic melanoma, this
115 ncer, but enzalutamide-resistant, lethal, or incurable disease invariably develops.
116                                         This incurable disease is caused primarily by the bacterium C
117 s report discusses how a number of currently incurable diseases might be treated by advances develope
118          Idiopathic pulmonary fibrosis is an incurable disease of unknown etiology.
119 velopment of therapeutic strategies to treat incurable diseases of the nervous system, including trau
120                  Multiple myeloma remains an incurable disease plagued by high relapse rates.
121 V) chronic infection, a long-studied but yet incurable disease, remains a major public health concern
122 y arterial hypertension (PAH) is a medically incurable disease resulting in death from right ventricu
123  may be repurposed for the treatment of this incurable disease.SIGNIFICANCE STATEMENT Despite intense
124  resistant prostate cancer (CRPC) remains an incurable disease stage with ineffective treatments opti
125  study point to new drug targets in CRPC, an incurable disease state which remains the chief therapeu
126 minal illness acknowledgment, recognition of incurable disease status, knowledge of the advanced stag
127 and the very indolent nature of nevertheless incurable diseases such as follicular lymphoma, which ha
128 onic lymphocytic leukemia (B-CLL) remains an incurable disease that requires innovative new approache
129 isease represents a group of progressive and incurable diseases that are characterised by selective l
130                      Although SMA remains an incurable disease to date, recent advances in the field
131  Adult T-cell leukemia/lymphoma (ATLL) is an incurable disease where most patients succumb within the
132 advances in therapy, glioblastoma remains an incurable disease with a dismal prognosis.
133                                    CLL is an incurable disease with a heterogeneous clinical course,
134 thought to represent cures in this otherwise incurable disease with conventional modalities.
135                     Glioblastoma (GBM) is an incurable disease with high intratumoral heterogeneity.
136  therapies, multiple myeloma (MM) remains an incurable disease with high unmet medical need.
137 ced or metastatic urothelial carcinoma is an incurable disease with limited treatment options, especi
138 tatic breast cancer (mBrCa) is most often an incurable disease with only modest responses to availabl
139 Low-grade lymphomas are generally considered incurable diseases with current standard therapies.
140 amous cell carcinoma (HNSCC) is generally an incurable disease, with patients experiencing median sur
141 enewed interest as a treatment for otherwise incurable diseases, with several GT products already on
142 ting peripheral neuropathies are progressive incurable diseases without effective treatment.

 
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