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1 t cancer drivers operating in a Galpha(q/11)-independent manner.
2 l lobe are inhibited by odors in an identity independent manner.
3 otein (Galpha(i), Galpha(s) or Galpha(q/11))-independent manner.
4 DosR (a noncognate RR) in a phosphorylation-independent manner.
5 amyloid-driving strands F and H in a tissue-independent manner.
6 signaling, GLI1 is activated in a Smoothened-independent manner.
7 tyrosine (Y) residue 969 (Y969) dependent or independent manner.
8 esses the kinase activity of c-Src in an APC-independent manner.
9 from of oncogene-induced RS in a checkpoint-independent manner.
10 levels of collagen in an apparently laminin-independent manner.
11 proteins to the nascent phagophore in a TFEB-independent manner.
12 tern is altered by high-fat diet in a ligand-independent manner.
13 ichiometric complex with CaM in a nucleotide-independent manner.
14 in ubiquitination and clearance, in a parkin-independent manner.
15 rophic differentiation in vitro, in a kinase-independent manner.
16 f mRNAs in a translation-dependent, RNase H1-independent manner.
17 y in a glutamate-dependent, action potential-independent manner.
18 d type 2 immune responses in an inflammasome-independent manner.
19 nitiate ZGA in either a Dux-dependent or Dux-independent manner.
20 transcript supports axon growth in a coding-independent manner.
21 low iron fitness in Msmeg, in a siderophore independent manner.
22 and 2) that IGF may stimulate ER in an E(2)-independent manner.
23 al cancer cell proliferation in an anchorage-independent manner.
24 pathways PI3K-AKT and MEK-ERK in the BCR/BTK-independent manner.
25 domain, can activate MAP kinases in a ligand-independent manner.
26 on potential of HPKs in an adhesion- and MMP-independent manner.
27 ions could be discussed in an open, software-independent manner.
28 -bearing organ, the bacteriome, in a PGRP-LC-independent manner.
29 n a Ca(v)1.2-independent and store depletion-independent manner.
30 somes to increase protein synthesis in a CAP-independent manner.
31 lamellipodium buckles upward in a myosin II-independent manner.
32 e damaged DNA after UV irradiation in a DDB2-independent manner.
33 bilization of Ctn RNA occurred in an editing-independent manner.
34 curs in a temperature- and sympathetic nerve-independent manner.
35 ly in a farnesylation-dependent but membrane-independent manner.
36 n the airways in an IL-33-dependent but TRL4-independent manner.
37 ProP concentrated at the cell poles in a CL-independent manner.
38 f anthocyanins, in a tissue- and development-independent manner.
39 n to block cancer progression in an androgen-independent manner.
40 behaviors in a light-dependent but circadian-independent manner.
41 specificity and inhibits Src in an activity-independent manner.
42 hate nucleotidohydrolase in an interleukin 6-independent manner.
43 ble and particulate antigens in an IFN-gamma-independent manner.
44 lated cytokines from keratinocytes in a PAR2 independent manner.
45 a vascular endothelial growth factor (VEGF)-independent manner.
46 maturation by binding pre-miR-10a in a DICER-independent manner.
47 sion of IGFBP3 in both DNMT3a-dependent and -independent manner.
48 dose-dependent but pyruvate kinase activity-independent manner.
49 d production of IFN-gamma and IL-4, in an Ag-independent manner.
50 retention of male structures in an androgen-independent manner.
51 cleosomes in a DNA replication- and sequence-independent manner.
52 ntial for Ndc80 degradation in a microtubule-independent manner.
53 transactivate FOXM1 target genes in a kinase-independent manner.
54 ific expression in a LFS-dependent but auxin-independent manner.
55 ML stem/progenitor cells in a BCR-ABL kinase-independent manner.
56 stance from falling to low levels in a light-independent manner.
57 er a broad range of length scales in a model-independent manner.
58 nduced senescence phenotypes in a PARylation-independent manner.
59 V-1, also prevents virion assembly in a BST2-independent manner.
60 ammals) regulate circadian timing in a light-independent manner.
61 the NuRD complex, in a glucose concentration-independent manner.
62 in turn activates IMM constriction in a Drp1-independent manner.
63 after exposure to A. fumigatus in a dectin-1-independent manner.
64 oncogenic translocations in a transcription-independent manner.
65 d upon DNA damage and is translated in a CAP-independent manner.
66 l of iCGI transcription in a DNA-methylation independent manner.
67 RCC to gain extracellular nutrients in a p53-independent manner.
68 the secretion of IFN-gamma in a cell contact-independent manner.
69 e death of infected plants in a largely NBR1-independent manner.
70 Fosb and Fos AP-1 factors in a beta-catenin-independent manner.
71 ication processes where Dl signals in an ubi-independent manner.
72 permit disaggregation to occur in an energy-independent manner.
73 biquitinating cyclin D1 in a phosphorylation-independent manner.
74 lization in a glycogen synthase kinase 3beta-independent manner.
75 d in cis during transcription and in a Rad51-independent manner.
76 nd actomyosin dynamics in VSMCs in a mitosis-independent manner.
77 as shown to be able to activate Dl in an ubi-independent manner.
78 at heterochromatic regions in a replication-independent manner.
79 the translation of viral late mRNAs in a cap-independent manner.
80 o host resistance in a T cell receptor (TCR)-independent manner.
81 olded proteins against aggregation in an ATP-independent manner.
82 eading to increased resistance in a mutation-independent manner.
83 dation through the proteasome in a ubiquitin-independent manner.
84 ABA is a prosurvival factor for Mks in a Tpo-independent manner.
85 sed activation of the inflammasome, in a PKR-independent manner.
86 y Ulp1 destabilizes Smo in a phosphorylation independent manner.
87 tivity in a DNA binding-dependent and ligand-independent manner.
88 ives tumor initiation and growth in an Eiger-independent manner.
89 as found to influence aortic strain in a sex-independent manner.
90 ptors on glutamatergic neurons in an insulin independent manner.
91 in a glutaminolysis-dependent and autophagy-independent manner.
92 nd D76N beta2-m fibril formation in a Ca(2+)-independent manner.
93 b also promotes CZ targeting but in a Sema3D-independent manner.
94 to modulate cell contraction in a RhoA-ROCK-independent manner.
95 t it represses cAMP signalling in an agonist-independent manner.
96 ectly interacts with the beta2AR in a ligand-independent manner.
97 itors that can form 3D colonies in a hormone-independent manner.
98 Mdm2 results in genomic instability in a p53-independent manner.
99 target genes in a methyltransferase activity-independent manner.
100 suppressing tumor growth in an inflammasome-independent manner.
101 exosomes that can infect cells in a receptor independent manner.
102 ulent P. sojae strains may function in an SA-independent manner.
103 ion of viral structural proteins in a factor-independent manner.
104 ted against diet-induced NASH, in an obesity-independent manner.
105 tion and cell proliferation in a bromodomain-independent manner.
106 onse is impaired in a type I and type II IFN-independent manner.
107 hibited HIV-1 release in a Vpu- and tetherin-independent manner.
108 gands in a rapid, reversible, titratable and independent manner.
109 hypoxia inducible factor 1alpha (HIF-1alpha)-independent manner.
110 es in a GTP-dependent but tRNA translocation-independent manner.
111 romoter is activated by the pathogen in a SA-independent manner.
112 production in MDMs in a type-I IFN- and TLR-independent manner.
113 ssion can occur in a physical and signalling-independent manner.
114 ron production in a STING-dependent but cGAS-independent manner.
115 ment (via TBK1 activation) in a PINK1-Parkin independent manner.
116 lix domain (WHD) and binds DNA in a sequence-independent manner.
117 nhanced LTP formation in a protein-synthesis-independent manner.
118 D4(+) and CD8(+) T cell activation in a Treg-independent manner.
119 okine expression in a necroptosis and kinase-independent manner.
120 and IL-13 expression in the lung in a STAT6-independent manner.
121 ired B cell survival and activation in an Fc-independent manner.
122 tion of PKCzeta in a CD14-dependent and TLR4-independent manner.
123 crophage function in an LpSpl-dependent and -independent manner.
124 can respond to unrelated infections in an Ag-independent manner.
125 nted allergic airway inflammation in a STAT6-independent manner.
126 K9me3 occur in an oxygen-dependent but HIF-1-independent manner.
127 is, and accelerates healing in a DNA-binding independent manner.
128 h Tdp1 was recruited to only 5' DSBs in a Ku-independent manner.
129 ulated by the RNA chaperone, Hfq, in an RpoS-independent manner.
130 llar granule neuron precursor cells in a p53-independent manner.
131 alytic activity of VRK2 in a kinase activity-independent manner.
132 of DNA replication in an Rb phosphorylation-independent manner.
133 of cathepsin B, Tnf and Bid in a neutrophil-independent manner.
134 lrC (FlrC(C)) forms heptamer in a nucleotide-independent manner.
135 etinal degeneration occurred in a transducin-independent manner.
136 transcription of these genes in a catalytic-independent manner.
137 to be additive, although not in a completely independent manner.
138 n, suggesting YES1 regulates YAP1 in a Hippo-independent manner.
139 Ser63 and Ser73 after SSL exposure in a JNKs-independent manner.
140 bute to ERAD in an unconventional, catalysis-independent manner.
141 the action of beta-catenin in a largely PYGO-independent manner.
142 pression in a dose-dependent and DNA binding-independent manner.
143 K1/2/7, is activated by wounding in a MKK4/5-independent manner.
144 using available MS2 libraries in instrument independent manner.
145 henotypes in a Cdk8-dependent, transcription-independent manner.
146 or opposite directions in a largely position-independent manner.
147 n-transfer mechanism that proceeds in a RING-independent manner.
148 of immature viral particle assembly in a p6-independent manner.
149 elevated in the dnmt1(-/-) CMZ, but in a p53-independent manner.
150 but forkhead box A1-dependent and active, ER-independent manner.
151 ted invasion and metastasis in a BET protein-independent manner.
152 orming growth factor beta, in a MIDAS/cation-independent manner.
153 of ubiquitinated eS7A during UPR in an Ire1-independent manner.
154 n the ischemic myocardium in an infarct size-independent manner.
155 her a goal was reached in an action- and cue-independent manner.
156 , tubulogenesis, and survival in a PPARalpha-independent manner.
157 in inhibition of tumor cell growth in a p53-independent manner.
158 ntire transcript from degradation in a polyA-independent manner.
159 pressive functions both in p53-dependent and independent manner.
160 rowth of xenograft tumors in mice in a SMAD4-independent manner.
161 clinical relevant data anywhere, in a fully independent manner.
162 op formation by Rad51 and Rad54 in an ATPase-independent manner.
163 nase- and kinetochore-dependent, but ATM/ATR-independent manner.
164 tumors support angiogenesis in an HIF1alpha-independent manner.
165 ference based on relief from pain in an IDO1-independent manner.
166 motes histone methylation in a HIF- and 2-HG-independent manner.
167 ly detrimental to cellular fitness in a gene-independent manner.
168 oformans is inhibited by KCs in an IFN-gamma independent manner.
169 sport and Src signaling activity in a ligand-independent manner.
170 AK2 stability and activation in a proteasome-independent manner.
171 at CRL2 activates CSN5/CSN6 in a neddylation-independent manner.
172 r delivery of plasmid DNA in a plant species-independent manner.
173 the regulatory residue S264 in a calcineurin-independent manner.
174 promoting cellular senescence through a p53-independent manner.
175 ation at damaged sites, therefore in a miRNA-independent manner.
176 sting that SCHLAP1 may function in a SWI/SNF-independent manner.
177 ry bacterial infection in a largely pathogen-independent manner.
178 ns biofilm synergy in a contact and H(2)O(2)-independent manner.
179 capacity of the entire TCR complex in an HLA-independent manner.
180 nhancing NGF-TrkA signaling in a translation-independent manner.
181 3 protein translation in a methyltransferase-independent manner.
182 n trans-homophilic interactions in a calcium-independent manner.
183 LA circuit supports generalization in a time-independent manner.
184 ndrial clearance, albeit possibly in a PINK1-independent manner.
185 a cAMP, PKA and S256 phosphorylation (pS256)-independent manner.
186 tly bind bacterial pathogens in a complement-independent manner.
187 eceptor RIG-I through both Ub-dependent and -independent manners.
188 in both liver x receptor (LXR)-dependent and independent manners.
189 croptosis, in both RIPK1-dependent and RIPK1-independent manners.
190 cell death in both RIPK1-dependent and RIPK1-independent manners.
191 ys in these organisms that function in CenH3-independent manners.
192 utrophils in prostaglandin E2-dependent and -independent manners.
193 r in inflammasome-dependent and inflammasome-independent manners.
194 at telomeres in a RAD52-dependent, but RAD51-independent, manner.
195 in in an inflammation-dependent, but antigen-independent, manner.
196 an O-acetylation-dependent, but xylosylation-independent, manner.
198 found that the binding occurred in a Ca(2+)-independent manner and did not involve the PCh-binding s
199 n resistance in a hypoxia-inducible factor 1-independent manner and impaired insulin signaling in liv
200 at this DSP domain acts as a ligand in a RGD-independent manner and is involved in intracellular sign
201 single DNA molecular regulator in a sequence-independent manner and its applications in three-dimensi
202 this context, CD55 functions in a complement-independent manner and required lipid raft localization
203 termediates of misfolding proteins in an ATP-independent manner and sequester them in sHsp/substrate
204 pts behavioral inhibition in a GRK3/arrestin-independent manner and suggests that KOR antagonists cou
205 keratinocytes in an EGF-dependent, integrin-independent manner and that formation of this complex is
206 ith the GREB1 promoter and enhancer in an E2-independent manner and that NCOA6 knockout reduces chrom
207 tive chromatin in both an RNA-dependent and -independent manner and that this association is abolishe
208 interacted with FAM20C in a kinase-activity independent manner and the binding was direct in vitro.
210 tive oxygen species-dependent and cell death-independent manner and was associated with mitochondrial
211 ome formation, PERK acted in a transcription-independent manner and was required at a post-sequestrat
212 n LPS challenge occurs in a protein kinase A-independent manner and, rather, is associated with inhib
213 is cleaved off by PorU sortase in a sequence-independent manner, and anionic lipopolysaccharide (A-LP
214 dergo degranulation in an IgE-dependent and -independent manner, and can be readily cultured in vitro
215 regulates genomic stability, in a catalytic independent manner, and its loss confers sensitivity to
216 igase RNF8 in a Piwi-interacting RNA (piRNA)-independent manner, and MIWI stabilization sequesters RN
217 ins, promotes TDMD in a tailing and trimming-independent manner, and regulates miRNA expression in mu
218 f nTh1 cells that express IFNgamma in a Tbet independent manner, and whose expansion can be enhanced
219 peptide revealed that it acts in a sequence-independent manner as an open-channel NMDAR antagonist a
221 crostructural morphology and mechanics in an independent manner because colloidal gels are formed by
222 tive activity and apoptosis in a caspase-3/9-independent manner, both in vitro and in vivo in a tumor
223 e when stimulated in a T cell receptor (TCR)-independent manner but failed to do so in TCR-dependent
224 reduced axillary bud number in a photoperiod-independent manner but promoted floret development only
225 o isoforms of the hKv7.4 channel in a Ca(2+)-independent manner but that only the long isoform (hKv7.
226 keratinocyte differentiation in an adhesion-independent manner by dampening Epidermal Growth Factor
227 interacts with the polypeptide in a sequence-independent manner by inducing a short beta-strand.
228 (sHSPs) delay protein aggregation in an ATP-independent manner by interacting with client proteins t
229 lar organization is modified in a brain size-independent manner by sex (relative expansion of total c
230 ent of the BTR complex to telomeres in a PML-independent manner bypasses the need for PML in the ALT
231 tic setpoint for blood glucose in an insulin-independent manner, consistent with a role for the brain
232 TSC1/TSC2/TBC1D7 protein complex and mTORC1-independent manner, contributing to intrinsic resistance
233 pu counteracts tetherin in a largely species-independent manner, degrading both the long and short is
234 gnaling hyperactivation, albeit in GSK-3beta independent manner, differentiated colon cancer in claud
235 tream facilitates promoter melting in an ATP-independent manner, distinct from a DNA translocase acti
236 ontrast, MPs activate translation in an mTOR-independent manner due, at least in part, to proteasomal
237 . coli fermentation can continue in a growth-independent manner during nitrogen limitation, while amm
239 ver, opioids may also function in a receptor-independent manner, especially in neural stem cells (NSC
240 ound that OCT4 and SOX2 operate in a largely independent manner even at co-occupied sites, and that t
241 onstrate that UTX, in a demethylase activity-independent manner, facilitates conversion of inactive e
242 age, binds double-stranded DNA in a sequence-independent manner, facilitates processing of damaged DN
243 This system can be activated in a convertase-independent manner from intracellular stores of the comp
244 ecific binding site can take place in a path-independent manner given reasonable values of the free e
245 te Montipora white syndrome in a temperature-independent manner had similarly reduced virulence.
246 ) serum enhanced HAdV-5 transduction in a FX-independent manner in CHO-CAR and SKOV3-CAR cells (CHO o
247 or (SLPI) is regulated by the AR in a ligand-independent manner in CRPC cells and required for CRPC c
248 er, we show that Casp-8 acts in a cell death-independent manner in ECs to regulate the formation of t
249 mulate bICP0 E promoter activity in a ligand-independent manner in mouse neuroblastoma cells (Neuro-2
251 Ubqln4 engages the J proteins in a J-domain-independent manner, in contrast to the previously report
252 nusual mechanism for binding ATP in a Mg(2+)-independent manner, including a rare hydrophobic bridge
253 FN trafficking in a transcription- and SMAD-independent manner, is a direct and rapid inducer of the
254 eased expression of Ccl5 and Cxcl10 in a p53-independent manner, mediating increased infiltration of
255 rgeted Nrf2 for degradation in a proteolysis-independent manner; NS2B3 licensed Nrf2 for lysosomal de
256 Syk mediates bronchoconstriction in a NO-independent manner, presumably via rho kinase and p38 MA
259 cardiomyocytes and interact in a bromodomain-independent manner, revealing a new functional interacti
260 t Parkin affects mtDNA levels in a mitophagy-independent manner.SIGNIFICANCE STATEMENT Parkinson's di
261 virus encoding mitochondrial PB2, in a MAVS-independent manner, suggesting a role for PB2 within the
262 d vascular integrin, bound to CD40L in a KGD-independent manner, suggesting that alphavbeta3 is a new
263 three isoforms bound to F-actin in a Ca(2+)-independent manner, suggesting that binding of only one
264 LPS), which stimulates B cells in an antigen-independent manner, suggesting that rapamycin specifical
265 nd binds to ~500 mRNAs in vivo in a sequence-independent manner that favors embryonic mRNAs with low
267 ansgene expression in a hyaluronic acid-CD44 independent manner that is down-regulated by inhibitors
268 an FcgammaRIIA-dependent and TLR7- and TLR9-independent manner that likely contributes to local tiss
269 LEDGF/p75 interacts with SSRP1 in an hSpt16-independent manner that requires the PWWP domain of LEDG
270 se transitions in a nucleotide-dependent and independent manner, thereby adding another layer of regu
271 te the expression of PCH1 and PCHL in a phyB independent manner, thereby increasing the response to r
272 hypoxia-inducible factor 1alpha (Hif1alpha)-independent manner, thereby promoting glutamine-based an
274 tions that shape-sensing occurs in a tension-independent manner through integrin beta3 signaling path
276 ere their products localize in a translation-independent manner, thus challenging the transcription-t
278 ciates with autosomes of germ cells in a DCC-independent manner to enrich H4K20me1 and trigger chromo
279 ient to sustain intrinsic signaling in a LIF-independent manner to promote ES cell pluripotency and s
280 ulates muscle GLUT4 expression in an insulin-independent manner under conditions of insulin resistanc
281 hore phosphorylation by the CPC in a tension independent manner via a microtubule-binding site on the
283 ls in a VEGF-independent and neoangiogenesis-independent manner, was upregulated in novel biomimetic
284 recapitulate signaling activity in a ligand-independent manner when fused to chemical or optical dim
285 F1 drove wild-type RAS activation in an EGFR-independent manner, whereas KRAS(G13D) weakly interacted
286 sense and respond to temperature in a shoot-independent manner, whereas shoot temperature responses
287 cell death in a caspase-1-, ASC-, and NLRP3-independent manner, whereas the presence of cholesterol
288 er chromatin accessibility in an HIF1/2alpha-independent manner, which could contribute to immunosupp
289 in a Tir-dependent but actin polymerisation-independent manner, which was enhanced by priming with i
290 ion sensitizes cells to ferroptosis in a p53-independent manner while ARF depletion induces NRF2 acti
291 lyzed by UBE2E family of E2 enzymes in an E3-independent manner while the conjugated-ubiquitin (Ub) i
292 ohol signals hypothalamic neurons in a vagal-independent manner, while fat and satiation signals requ
293 ed IFN-I in a cGAS-STING-dependent and MyD88-independent manner, while we confirmed plasmacytoid dend
294 d by membrane recruitment, in an orientation independent manner with no additional contributions prov
295 hing show that human FZD4 assembles-in a DVL-independent manner-with Galpha12/13 but not representati
296 uired for phosphorylation of STATs in a SMAD-independent manner within minutes of TGF-beta stimulatio
297 espan in an Hsp70 chaperone-dependent and CR-independent manner without increasing H2O2 scavenging or
298 genous PCR-generated sequences in a homology-independent manner without loss of additional nucleotide
299 gger changes in gene expression in a pathway-independent manner without the need for exogenous induce
300 le full-length oxFA species in a regioisomer-independent manner without the need for time-consuming s