ライフサイエンスコーパス: indiscriminately

1 h targets both mammalian and bacterial cells indiscriminately).

2 ess the correct AG, but can attack other AGs indiscriminately.

3 lock all receptor-coupled signaling pathways indiscriminately.

4 y- and material-intensive and leach elements indiscriminately.

5 y just process autosomal and sex chromosomes indiscriminately.

6 gnosing CNS infection but should not be used indiscriminately.

7 atible as MAT kills sterile and 'wild' males indiscriminately.

8 initiate replication seem to bind chromatin indiscriminately.

9 clinically important antimicrobials are used indiscriminately.

10 erneuronal synaptic and autaptic connections indiscriminately.

11 s display pervasive fear memories, expressed indiscriminately.

12 if the background levels are allowed to rise indiscriminately.

13 etic fluorescent indicator dyes label tissue indiscriminately.

14 ly adverse impact that IPM carries when used indiscriminately.

15 and optimal 5' exon and lariat intermediates indiscriminately.

16 successful than mediator-specific drugs used indiscriminately.

17 that the mid-14th-century Black Death killed indiscriminately.

18 tial pulse voltammetry (DPV) are used rather indiscriminately.

19 g prophase I and instead seemed to associate indiscriminately.

20 ment for breast cancer, aromatase inhibitors indiscriminately abolish estrogen synthesis in all tissu

21 Clutter echoes indiscriminately activate multiple parts in the null-det

22 In contrast, radiation indiscriminately activated all ErbB species with the act

23 pus after doxorubicin treatment, whereas DRF indiscriminately activated Nrf2 in the hippocampus of ve

24 Here, we isolated a variant of DivIVA that indiscriminately activates sigma(F) in both daughter cel

25 Indeed, most current treatments indiscriminately affect both the autoreactive T cells an

26 Circulating sFlt-1 may indiscriminately affect endothelial function and the mic

27 ression by naive T cells, which is activated indiscriminately after parasitism.

28 MPO generates antimicrobial oxidants, which indiscriminately and effectively kill phagocytosed patho

29 quo therapeutic strategies that target TAMs indiscriminately and in favor of strategies that specifi

30 germ cells migrate into gonads of either sex indiscriminately and may be functional even across a spe

31 However, current devices stimulate indiscriminately and therefore cannot reproduce the intr

32 begin by generating a variety of strategies indiscriminately, and experience teaches them to select

33 tance, solubility or propensity to aggregate indiscriminately, and is thus dependent solely on the ov

34 hat occur when toxicology tests are obtained indiscriminately, are misapplied, or are misunderstood a

35 on by binding inside the ribosome tunnel and indiscriminately arresting the elongation of every nasce

36 It is not known whether they act indiscriminately as general modulators of transcription

37 When coexpressed, TLR4 indiscriminately associates in the endoplasmic reticulum

38 ein, and whose disruption permits Mfd to act indiscriminately at transcription complexes that lack th

39 ability of BLyS to increase B cell survival indiscriminately, at either a resting or activated state

40 Synbiotic treatment indiscriminately attenuated the stress-induced immune an

41 Sexually explicit material is now indiscriminately available to youth, and studies have li

42 h an array of nonspecific nucleases degrades indiscriminately based on target size or ribosome protec

43 We conclude that EIS cannot indiscriminately be used in the screening evaluation of

44 -box on the P4Halpha(I) promoter appeared to indiscriminately bind with either USF1 or USF2, with a s

45 al gap of knowledge, leading to therapeutics indiscriminately blocking IL-17A and global inhibition o

46 sol of CCs do enter the translocation stream indiscriminately but are also subject to distributive fo

47 Red/green cones were coupled indiscriminately but blue cones were rarely connected wi

48 natural products that bind to these proteins indiscriminately but with nanomolar affinity.

49 C57 females used this strategy indiscriminately, but DBA females sampled as a function

50 nitially reached toward the baited container indiscriminately, but gradually and with the aid of colo

51 xpectation violation does not enhance memory indiscriminately, but specifically aids the disambiguati

52 mentation of the mutated proteins is blocked indiscriminately by nucleotides.

53 Although it appeared that GN adsorbed PAHs indiscriminately compared to MWCNTs, the subsequent bioa

54 r highly divergent axons, inhibitory neurons indiscriminately contact most neighbouring pyramidal cel

55 dules bind in general with high affinity but indiscriminately, cross-species binding is rare.

56 to a cationic cell-penetrating peptide, were indiscriminately cytotoxic independently of p53 status.

57 clinically deployed today are designed to be indiscriminately cytotoxic, however, achieving selective

58 rge range of diverse substrates, it does not indiscriminately degrade all RNAs.

59 uble-stranded DNA (dsDNA) (cis-activity) and indiscriminately degrade single-stranded DNA (ssDNA) (tr

60 me, annotated as an IMP, is nonspecific, and indiscriminately dephosphorylates ARAPDP along with ribu

61 A noninvasive technology that indiscriminately detects tumor tissue in the brain could

62 We show that E4orf3 indiscriminately drives high nucleosomal density of vira

63 imarily disease-causing bacteria rather than indiscriminately eliminating natural gut flora.

64 Current therapeutics indiscriminately enhance the activity of the endogenous

65 e, we demonstrate that this tolerance is not indiscriminately extended to all bacteria encountered in

66 In 8-year-olds, these regions were recruited indiscriminately for detail recollection and item recogn

67 ically, young children engaged RLPFC and IPL indiscriminately for first-order and second-order relati

68 timicrobial agents continue to be prescribed indiscriminately for upper respiratory infections.

69 ernatively, Peters' rule posits that neurons indiscriminately form connections with other neuron type

70 ese retinal ganglion cells draw their inputs indiscriminately from a coarse-grained mosaic of red and

71 ound that excess connectivity is established indiscriminately from among glutamatergic afferents.

72 we provide evidence that Srs2 removes Rad51 indiscriminately from DNA, while the Rad52 protein coord

73 ls cannot do this because they receive input indiscriminately from M and L cones.

74 the TVB-NRG1 bridge protein receives inputs indiscriminately from S1 input sources.

75 lls the expressed H-type alpha1,2FT does not indiscriminately fucosylate terminal galactosyl residues

76 rm competition, Peromyscus polionotus, sperm indiscriminately group with unrelated conspecific sperm.

77 he ability of Cas12a to cleave nucleic acids indiscriminately has been harnessed for many application

78 sh functional connections with L and M cones indiscriminately, implying that the cone-selective circu

79 ore, the rats with lesions not only searched indiscriminately in all four quadrants, they also did no

80 osteroids have previously been used somewhat indiscriminately in patients with severe AH, but effecti

81 lgi merozoites invade monkey red blood cells indiscriminately in vitro, in humans, they are restricte

82 opose that the Pro-253 --> Arg mutation will indiscriminately increase the affinity of FGFR2 toward a

83 posed to NGF via bath perfusion, rapidly and indiscriminately increased the rate of spontaneous firin

84 for treating human disease is limited due to indiscriminately increasing H(+) conductance across all

85 rus (VV) and canarypox virus (ALVAC), do not indiscriminately infect all cell types of the primary hu

86 We propose that EBV indiscriminately infects B cells in mucosal lymphoid tis

87 While opioids indiscriminately inhibit all GABAergic inputs onto all P

88 While u-opioids indiscriminately inhibit GABAergic inputs onto all PAG n

89 reduced the amount of the large subunit and indiscriminately inhibited mitochondrial translation.

90 egradation of newly synthesized APOBEC3G but indiscriminately inhibits encapsidation of "old" and "ne

91 -binding domain, a structural motif known to indiscriminately interact with tRNAs.

92 , we demonstrate that the protein integrates indiscriminately into virtually any biological membrane,

93 unologically naive, that the epidemic killed indiscriminately, irrespective of age, sex, or frailty.

94 nt over current chemotherapeutic agents that indiscriminately kill proliferating cells.

95 neurotropic flaviviruses, as West Nile virus indiscriminately killed both tumor and normal neural cel

96 The findings confirm that RYGB does not indiscriminately lower body weight but specifically prev

97 y assayed by formaldehyde application, which indiscriminately modifies proteins and is presumed to ca

98 The accumulation of MG indiscriminately modifies proteins, including important

99 We show that the PAFc is indiscriminately necessary for the proliferation of AML

100 results suggest that miRNAs are incorporated indiscriminately of their sequence into Ago1 through Ago

101 wareness of emergent risks from LLMs trained indiscriminately on web-scraped data, particularly in he

102 Clinicians frequently but at times indiscriminately perform computed tomography scans for c

103 A) polymerases, which act in the nucleus and indiscriminately polyadenylate all mRNA, Cid13 is a cyto

104 ctors of DNA-binding or RNA-binding residues indiscriminately predicting interactions with both nucle

105 Depletion of Ca2+ indiscriminately prevented the nuclear import of macromo

106 r key components of innate immunity, did not indiscriminately promote intracellular infections (Mycob

107 nti-tubulins, auristatins and maytansinoids, indiscriminately radiosensitize tumour cells, conjugatin

108 nearby area and target excitatory neighbors indiscriminately, raising the issue of how neuronal acti

109 in widespread use for killing microorganisms indiscriminately, rapidly, and by nonspecific action.

110 and other animals do not use social learning indiscriminately, rather, natural selection has favoured

111 A second-site suppressor, ExbB(A39E), indiscriminately reactivated the majority of H20 substit

112 LiF-MS peptide ligands carry a short-lived, indiscriminately reactive cleavable crosslinker that mar

113 e, but the antisera of both conjugates could indiscriminately recognize each carbohydrate hapten.

114 Acutely infected brains and spinal cords indiscriminately recruit a homogeneous population of ear

115 analysis suggests that canonical AP-1 motifs indiscriminately recruit all AP-1 subunits to genomic si

116 critical question follows: Are older adults indiscriminately redundant, or do they modulate their us

117 nd external tufted cells, and, in turn, they indiscriminately release GABA onto principal neurons.

118 These systems often indiscriminately remove both harmful and protective anti

119 break relatedness are phenotype-naive; they indiscriminately remove subjects to break relationship,

120 le's choices (regardless of confidence) were indiscriminately represented across vmPFC.

121 kinetochores initially bind to microtubules indiscriminately, resulting in errors that must be corre

122 CD-1 aggressors attacked males and females indiscriminately, resulting in stress resilient and susc

123 l cells get mixed L and M cone input, likely indiscriminately sampled from the randomly arranged cone

124 Yet, most drugs indiscriminately saturate the cell.

125 d specificity of this complex, and that CD14 indiscriminately serves to deliver the ligand to TLR4.

126 f emotionally withdrawn (inhibited type) and indiscriminately social (disinhibited type) reactive att

127 Consistent with its niche, Exaiptasia indiscriminately stings for defense and expresses a Ca(V

128 Although high concentrations of exogenous NO indiscriminately suppress the proliferation and differen

129 Adenosine at a concentration of 30 uM indiscriminately suppressed connections with either an u

130 ver, how such patterns, which are thought to indiscriminately synchronize nearby cells, could provide

131 rase inhibitors display limited specificity, indiscriminately targeting all enzymes that use AdoMet.

132 display limited specificity and selectivity, indiscriminately targeting many methyltransferase enzyme

133 gnaling functions of senescence suggest that indiscriminately targeting senescent cells or modulating

134 ing water productivity, probably because ABA indiscriminately targets all ABA receptors.

135 ts suggest that the Black Death did not kill indiscriminately-that it was, in fact, selective with re

136 Rather than maximizing energy indiscriminately, they seemed to assign subjective value

137 ulants or caged neurotransmitters, which act indiscriminately throughout the illuminated volume, chAR

138 uence, these data suggest A1 generally binds indiscriminately to all available pre-mRNA sequences.

139 characteristics of a DNA aptamer which binds indiscriminately to ATP, ADP, AMP, and adenosine.

140 A universal base must pair indiscriminately to each of the canonical bases with lit

141 anscriptome in comparison with TAMs isolated indiscriminately to function using established macrophag

142 pivotal role in enabling the peptide to bind indiscriminately to mu- and delta-receptors.

143 In contrast, core neurons responded indiscriminately to presentations of the SD tone or the

144 sistent with the propensity of S-DNA to bind indiscriminately to proteins.

145 inding to 5'SSs by binding cooperatively and indiscriminately to the pre-mRNA.

146 (VNO) displayed male-typical sexual behavior indiscriminately toward female and male conspecifics.

147 ls of 1a delaminate and release gaseous N(2) indiscriminately under paraffin oil, the crystals of 1b

148 Indeed, a constitutively active NICD indiscriminately up-regulates expression of both HERP1 a

149 global immunosuppression strategies that are indiscriminately used for all solid organ grafts.

150 bacteriophage T7 were grown to fix mutations indiscriminately, using a combination of population bott

151 lines results from males courting both sexes indiscriminately, whereas in other lines this phenotype

152 HV is able to infect a variety of cell types indiscriminately, while in healthy latent carriers KSHV

153 d tertiary structure and binds RNA sequences indiscriminately with a dissociation constant (Kd) of ap

154 a-Globin pre-mRNA (exons 1 and 2) is spliced indiscriminately with either SR protein.

155 nd that MT-projecting cells were distributed indiscriminately with respect to cytochrome oxidase comp

156 work, we explore the use of silanes to react indiscriminately with RNA such that the primary factor g

157 ed state is essential because CBP2 assembles indiscriminately with the bI5 RNA in any folding state t

158 L lacking the CAAX motif can still associate indiscriminately with the plasma membrane and retains it

159 s and, when overexpressed, Helios associates indiscriminately with the various Ikaros isoforms.

160 able exceptions, have come to reside largely indiscriminately within the several agr groups.