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1 in which endogenous cohesin can be silenced inducibly.
3 estion using a mouse model in which we could inducibly ablate PAX interacting (with transcription-act
5 nary disease (COPD); however, when Mig-6 was inducibly ablated in adult mice (Mig-6(d/d)), the lungs
10 hich MyoD or its nonacetylatable version was inducibly activated in mouse embryonic fibroblasts deriv
13 t3) which acts as a dominant negative, or an inducibly active Stat3-gyraseB chimera (Stat3-GyrB).
14 pulation of genetically modified cells to be inducibly amplified, thereby averting the risks associat
18 in which a dominant negative Nur77 mutant is inducibly and specifically expressed in mouse endothelia
22 ponse to calcium influx, Shc, Grb2, and Sos1 inducibly associate with a 180-kDa tyrosine-phosphorylat
24 n to bind to a GDP-exchange factor (C3G) and inducibly associate with the focal adhesion complex.
25 the carboxyl-terminal SH2 domain of PI3K to inducibly associate with the full-length SHP-1 protein.
28 rough the scaffold molecule Bcl10, which was inducibly associated with JNK2 and served as a JNK-inter
33 a Ste20-related serine-threonine kinase that inducibly associates with the adaptors SLP-76 and Gads a
35 binding mammalian gene product, is expressed inducibly at high levels and enterobactin-secreting resp
36 lathrin-binding protein fragment ("hook") is inducibly attached to an "anchor" protein at the plasma
37 kappaB subunits Rel A, NF-kappaB1, and c-Rel inducibly bind the TNF response element; these proteins
39 precipitation experiments revealed that BRG1 inducibly binds to the CIITA promoter despite the absenc
40 romoter in an ATM-dependent manner, and IRF7 inducibly binds to the endogenous retinoic acid-inducibl
41 romotes recruitment of Rac1 to IQGAP1, which inducibly binds to VEGFR2 and which, in turn, is associa
42 ral of these inducible Oct1 targets are also inducibly bound by Oct4 in embryonic stem cells followin
43 The majority of the identified loci are heat-inducibly bound by yeast HSF, and the target genes encod
44 ces that included heat shock elements, which inducibly bound heat shock factor 1, TATA-like elements,
45 utively by human granulocytes and testis and inducibly by keratinocytes, is modulated by an energy-de
47 llergic airway inflammation, we developed an inducibly CD28-deleting mouse strain or alternatively us
48 itope-tagged proteins were constitutively or inducibly coexpressed in protoplasts with amiRNA candida
49 pitope-tagged proteins are constitutively or inducibly coexpressed with individual amiRNA candidates
55 RIIA demonstrated that Fc gamma RIIA is also inducibly coupled to the serine/threonine and lipid kina
56 ng Cullin4 RING ubiquitin ligases (CRL4s) to inducibly degrade pathogenic proteins is emerging as a p
59 that maintain differentiated cells, here we inducibly delete the histone demethylase LSD1/KDM1A in a
62 e-Lox-based mouse model in which Chkl can be inducibly deleted from somatic epithelial cells in the a
63 sgenic mouse in which Mef2a, -c, and -d were inducibly deleted in adult nestin-expressing NSPCs and t
65 and metabolizing enzymes have been deleted, inducibly deleted, and knocked in as tagged or altered r
66 ng a mouse model in which endothelial Dhh is inducibly deleted, we found that endothelial Dhh both op
68 rythropoiesis in a cell-autonomous manner by inducibly deleting Trim28 exclusively in hematopoietic c
70 tion, we developed a genetic method that can inducibly deplete targeted proteins and that mimics thei
72 demonstrate the utility of this approach for inducibly disrupting excitatory neurotransmission, provi
73 C12 cell lines in which levels of GSH can be inducibly down-regulated via doxycycline induction of an
74 yme in de novo glutathione synthesis, can be inducibly downregulated in catecholaminergic neurons, in
75 he ETV1 promoter is used to specifically and inducibly drive Cre recombinase in ICC as a strategy to
76 y are currently limited by a narrow scope of inducibly dynamic stereocenters that can be readily epim
77 sis directly, LNCaP cells were engineered to inducibly express a constitutively activated form of the
78 ts DNA replication, we generated cells which inducibly express a constitutively active allele of RB (
80 so demonstrate that 3T3-derived cells, which inducibly express a dominant-negative BRG-1, arrest by P
81 proaches in skeletal muscle progenitors that inducibly express a master transcription factor, Pax7, w
83 ogical setting, we implemented a strategy to inducibly express active MLK3 in the preformed acini of
88 riant, we generated stable cell lines, which inducibly express DeltaNp73alpha, DeltaNp73beta, and var
89 99 lung carcinoma and U118 glioma cells that inducibly express Dkk-1 under a tetracycline-regulated p
90 scle-specific gene expression, in cells that inducibly express dominant negative versions of Brahma (
91 on, we introduced Mitf into fibroblasts that inducibly express dominant negative versions of the SWI/
92 ere we have developed an efficient method to inducibly express double-stranded RNA hairpins and demon
94 s we used immortalized cortical neurons that inducibly express either a full-length tau isoform (T4)
95 n of EGFP-S was examined in cell lines which inducibly express either wild-type CK2 holoenzyme or a C
98 tracycline-regulated NIH-3T3 cell lines that inducibly express either wild-type Pak1, a kinase-dead,
100 we used adenovirus-mediated gene transfer to inducibly express FLAG-tagged mouse NSMase-2 in primary
101 his, we have developed novel cell lines that inducibly express FLAG-tagged versions of either the pho
102 e-regulatable RT4 schwannoma cell lines that inducibly express full-length merlin with mutations at t
106 reated a HEK293-based cell culture system to inducibly express individual interferon-stimulated genes
107 "knock-in" Cre-estrogen receptor alleles to inducibly express K-RasG12D in CC10(+) epithelial cells
108 xpression, we have generated cell lines that inducibly express mutant forms of the BRG1 or BRM ATPase
110 rebellar ataxia 17 (SCA17) knockin mice that inducibly express one copy of mutant TATA box binding pr
112 several MCF7 adenocarcinoma cell lines that inducibly express p73 or p53 under a tetracycline-regula
113 stablished several groups of cell lines that inducibly express p73 under a tetracycline-regulated pro
115 ough the use of stable MCF7 cell lines which inducibly express short hairpin RNA targeting HDAC2, we
116 In U2OS and NCI-H1299 cells engineered to inducibly express the dominant-negative mutant E2F-1 (1-
117 ted cells as well as in clones engineered to inducibly express the mutant protein upon exposure to do
120 generated several groups of cell lines that inducibly express various p53 mutants using a tetracycli
121 ing VACV recombinants that constitutively or inducibly express VETF subunits and RAP94 with affinity
123 gene expression profiles in cell lines that inducibly express wild-type and mutant Vpr proteins.
126 y in HeLa cells and in HeLa cell lines which inducibly expressed a dominant interfering mutant of dyn
127 antly reduced the cell surface expression of inducibly expressed alpha2B-AR and arrested the receptor
129 f leaf development, juvenile leaf cells that inducibly expressed Arabidopsis ABP1 prematurely advance
130 ctin turnover by monitoring incorporation of inducibly expressed beta-actin-GFP in adult mouse hair c
137 ermediary factor 1 beta (TIF1beta) as a gene inducibly expressed early during myeloid differentiation
139 rodimeric transcription factor containing an inducibly expressed HIF-1alpha subunit and a constititut
140 rodimeric transcription factor containing an inducibly expressed HIF1alpha subunit and a constitutive
141 Ligand binding analyses confirmed that human inducibly expressed hsp-70-bound 25-OHD3 with approximat
143 of glycan changes in pancreatic disease, we inducibly expressed human fucosyltransferase 3 and beta1
144 h a constitutively active form of Akt can be inducibly expressed in adult skeletal muscle and thereby
146 s that are constitutively expressed, MCL1 is inducibly expressed in cells that are recently exposed t
147 stabilized (t1/2 approximately 3.5 hr) when inducibly expressed in either quiescent or proliferating
149 Together, these results show that Cyr61 is inducibly expressed in granulation tissues after woundin
150 ator (Aire), a transcriptional regulator, is inducibly expressed in human and mouse tumor keratinocyt
151 ated variant of androgen receptor (TC-AR) is inducibly expressed in LNCaP, an androgen-dependent cell
153 this study, we demonstrate that gV-sPLA2 is inducibly expressed in mouse and human macrophages (M) a
155 haracterized inhibitor IkappaB delta is also inducibly expressed in response to inflammatory stimuli.
156 ost probably has a mononuclear Fe center, is inducibly expressed in roots as well as in leaves of Che
157 hese studies demonstrate that a RASSL can be inducibly expressed in several mouse tissues and used in
162 asion of host cells has been disrupted using inducibly expressed oligonucleotide external guide seque
163 ppaB) and induces cell death, whereas TNFR2, inducibly expressed on endothelial cells and on TECs by
164 lipid antigen-presenting molecule, which is inducibly expressed on monocytes and dendritic cells.
165 families members, ICOS, PD-1, and BTLA, are inducibly expressed on T cells, and they have important
166 nerated multiple cell lines in which LSD1 is inducibly expressed or knocked down and found that LSD1
167 stitutively and p101 as a protein forming an inducibly expressed PI3Kgamma, (iii) differences in basa
170 xpression of c-Maf in myeloid cell lines, we inducibly expressed the c-Maf cDNA in 2 bipotent human m
171 ntify the bona fide target genes of Hog1, we inducibly expressed the spontaneously active variant Hog
172 cells and costimulates effector T cells, are inducibly expressed under harmful conditions, such as ma
173 of A6, we established a HeLa cell line that inducibly expressed VACV-A6, which allowed us to constru
175 we generated a double transgenic mouse that inducibly expresses a ligand-independent constitutively
176 ogeny, we have used a transgenic line, which inducibly expresses an inhibitor of BMP signaling, Noggi
179 addition, a recombinant vaccinia virus that inducibly expresses F9, like a previously described L1 m
180 a BALB/c-3T3 cell line (termed p27-47) that inducibly expresses high levels of this protein, we show
182 by p27Kip1, we constructed a cell line that inducibly expresses p27Kip1 upon addition of isopropyl-1
184 FosB by using a bitransgenic mouse line that inducibly expresses the protein in the NAc and dorsal st
185 ected insect Sf9 cell line (Sf9(VSV-G)) that inducibly expresses the VSV-G protein upon infection wit
186 his question, we generated Tet-On A431 cells inducibly expressing a desmoplakin (DP) mutant lacking t
188 nd mitotic catastrophe in osteosarcoma cells inducibly expressing a p27Kip1 mutant (termed p27K) that
189 blished several stable cell lines capable of inducibly expressing a p53 mutant alone, wild-type p53 a
190 nalysis of Rab1 purified from a yeast strain inducibly expressing AnkX revealed that this small GTPas
191 in confluence, fibroblasts constitutively or inducibly expressing BAD persisted in S phase, continued
194 21 overexpression in vivo, BHK21 cell clones inducibly expressing human p21 (Tet-p21) driven by the t
196 otypic cultures derived from transgenic mice inducibly expressing oncogenic beta-catenin and/or PIK3C
197 n adult tissue, we developed transgenic mice inducibly expressing p14(ARF) (human ortholog of murine
198 ion of p21(WAF1/CIP1) (i.e., in Jurkat cells inducibly expressing p21(WAF1/CIP1) under the control of
199 o DNA was confirmed in a 16HBE14o- cell line inducibly expressing PKC delta-CAT under the tet-off sys
201 stable human embryonic kidney 293 cell lines inducibly expressing the wild-type or kinase-defective d
206 ein (EGFP) and expressed this fusion protein inducibly in a HEK 293-based cell line to avoid possible
207 g transgenic mice overexpressing calcineurin inducibly in forebrain neurons, we now provide evidence
210 Several TLRs are expressed constitutively or inducibly in the intestine, and contribute to immune def
211 hic growth, we created mice where Myc can be inducibly inactivated, specifically in adult myocardium.
213 ural activity could then be specifically and inducibly increased in the hM(3)D(q)-expressing neurons
216 flammatory cytokines, the deubiquitinase A20 inducibly interacts with the regulatory molecules TAX1BP
217 nerated multiple cell lines in which ECT2 is inducibly knocked down and found that ECT2 knockdown tri
218 acquires its gain-of-function, mutant p53 is inducibly knocked down in the SW480 colon cancer cell li
219 cells, in which endogenous mutant p53 can be inducibly knocked down, to identify mutant p53 target ge
223 6R-yellow fluorescent protein (YFP) mouse to inducibly label nestin-expressing stem cells and their p
226 ped a mouse Hes1(CreERT2) knock-in allele to inducibly mark Hes1(+) cells and their descendants.
227 ivity compared to erythromycin A against the inducibly MLS (macrolide, lincosamide, and streptogramin
230 Several recombinant vaccinia viruses that inducibly or constitutively express an enhanced green fl
232 n which endogenous mutant R273H/P309S can be inducibly or stably knocked down, whereas a small interf
234 deed, derivatives of the HC11 cell line that inducibly overexpress an exogenous PKC alpha or ectopic
236 l-TRE-CXCL1 double-transgenic (Tg) mice that inducibly overexpress CXCL1 under the control of the ast
238 ality, in which a cloned "reference" gene is inducibly overexpressed in a set of mutant strains carry
240 RKO and MCF7 cell lines in that GPR87 can be inducibly overexpressed or knocked down by a tetracyclin
241 ates the activity of the p53 family, STX6 is inducibly overexpressed or knocked down in various cell
244 ng a noninvasive pharmacogenetic approach to inducibly perturb neuron activity postnatally, and ask i
246 ng TCR ligation, all of the CD3 ITAMs become inducibly phosphorylated and associate with the ZAP-70 p
247 l by an inhibitory subunit IkappaB, which is inducibly phosphorylated by an IkappaB kinase complex an
250 n essential component of the ribosome and is inducibly phosphorylated following mTOR activation in eu
253 guanine nucleotide exchange factor Vav1 was inducibly phosphorylated in a Syk-dependent manner in ce
254 vely associated with CD120a (p55) and become inducibly phosphorylated in macrophages in response to T
259 mice with serine-to-alanine mutations at the inducibly phosphorylated serine 310 alone or at conserve
260 ic labeling experiments indicate that Syk is inducibly phosphorylated to an even greater extent on se
261 response to TGF-beta, specific Smads become inducibly phosphorylated, form heteromers with Smad4, an
263 Here we report that the PPM1G phosphatase (inducibly recruited by nuclear factor kappaB [NF-kappaB]
264 gnificant fraction of human CD2 molecules is inducibly recruited into lipid rafts upon CD2 cross-link
267 ls, focal adhesion kinase (FAK) and PI3K are inducibly recruited to raft-associated membrane domains.
268 well as other members of the MCM family, is inducibly recruited to Stat1 target gene promoters in re
269 TCR signaling, the adaptor protein Bcl10 is inducibly recruited to the CARD11 scaffold protein as pa
270 actors ATF-2, c-jun, Egr-1, and Sp1 are also inducibly recruited to the TNF-alpha promoter in vivo, a
273 in which sustained transgene expression was inducibly regulated, both specifically and homogeneously
276 le in editing, we generated cell lines which inducibly replaced band IV protein with an enzymatically
278 testing (MIC, 8 microg/ml), one isolate was inducibly resistant to oxacillin (MIC of 16 microg/ml af
281 icient U251 glioblastoma cells engineered to inducibly restore PTEN upon exposure to doxycycline.
283 conditions under which beta-catenin might be inducibly stabilized in vivo would be inhibitory for T c
284 utively active Akt transgene, which could be inducibly targeted to the vascular endothelium using the
285 phage- and neutrophil-rich inflammation when inducibly targeted, in a transgenic fashion, to the adul
289 ned, the Src family kinases Fyn and Blk were inducibly tyrosine phosphorylated and activated by recep
290 s, such as ZAP-70, SLP-76, and pp36, are all inducibly tyrosine phosphorylated following TCR ligation
292 and 80 kDa exist and that these proteins are inducibly tyrosine phosphorylated in the response to sev
293 Despite this, the SLP-76 adapter protein was inducibly tyrosine phosphorylated, and both the Ras-mito
296 lenic B cells and in B cell lines capable of inducibly undergoing immunoglobulin SR on their chromoso
297 proteins that happen to be constitutively or inducibly unstable, and in this capacity it plays a regu
298 tionarily conserved Sin3L/Rpd3L complexes is inducibly up-regulated by inositol phosphates but involv
300 a 97-kDa cytosolic protein (p97), associates inducibly with SHP-2 upon cytokine stimulation and const