ライフサイエンスコーパス: inducing activity

1 roinflammatory cytokine with T helper type 1-inducing activity.

2 In vitro, GDF7 has potent sensory neuron-inducing activity.

3 ctivity that correlated with their apoptosis-inducing activity.

4 h the kinase NIMA and suppresses its mitosis inducing activity.

5 ly decreased or slightly increased apoptosis-inducing activity.

6 uniquely displays cancer-specific apoptosis-inducing activity.

7 h CD147 clustering and CD147-dependent MMP-1-inducing activity.

8 d but not sufficient for the differentiation-inducing activity.

9 lls showed that they have increased mesoderm-inducing activity.

10 Bix1 causes the protein to acquire apoptosis-inducing activity.

11 d displays membrane-targeting and cell death-inducing activity.

12 O- and 6-O-sulfate groups have potent bypass-inducing activity.

13 g to domain 1-3, was essential for IFN-gamma-inducing activity.

14 aragine within the prion domain reduce prion-inducing activity.

15 224 are both necessary for this second prion-inducing activity.

16 being entirely responsible for its mesoderm-inducing activity.

17 obox gene with non-cell-autonomous organizer-inducing activity.

18 mplete abolishment of its Ca(2+) oscillation inducing activity.

19 nt with proteinase K inhibited the apoptosis-inducing activity.

20 ndoderm is required for heart, but not head, inducing activity.

21 ulovirus eliminates both infectivity and IFN-inducing activity.

22 D was sufficient and necessary for NF-kappaB-inducing activity.

23 tenance, and stemness independent of its EMT-inducing activity.

24 form of ciliary ectosomes that retain signal-inducing activity.

25 rowth factor, and the acetylcholine receptor-inducing activity.

26 factors nodal, Xnr1 and Xnr2, lacks mesoderm-inducing activity.

27 osome 10 introduction did not alter secreted inducing activity.

28 does nonetheless possess some dermamyotomal-inducing activity.

29 C-cadherin completely inhibited beta-catenin-inducing activity.

30 h both specific and highly potent osteogenic-inducing activity.

31 of Hwa that dramatically abolishes its axis-inducing activity.

32 ode of action that results in a strong shoot-inducing activity.

33 Fgf8, but not by Fgf8b, which lacks neuronal inducing activity.

34 these properties without impacting apoptosis-inducing activity.

35 than the time of the elevated level of head inducing activity.

36 cytes have an extremely strong transcription-inducing activity.

37 luid (CSF) contain abnormally high IFN-alpha-inducing activity.

38 ure that significantly correlated with IL-17-inducing activity.

39 m fad7 and sfd1 did not reconstitute the SAR-inducing activity.

40 nes are required for accumulation of the SAR-inducing activity.

41 3,4-dihydroxymandelic acid demonstrated low inducing activity.

42 buted to its antiproliferative and apoptosis-inducing activity.

43 ased the proteasome-inhibitory and apoptosis-inducing activities.

44 ol-binding, and gamma interferon (IFN-gamma)-inducing activities.

45 forebrain-, midbrain- and rostral hindbrain-inducing activities.

46 factors, originally identified by their bone-inducing activities.

47 these Cdc25 isoforms increases their M-phase-inducing activities.

48 r with anti-inflammatory and phase II enzyme inducing activities.

49 for their sprouting-inhibiting and sprouting-inducing activities.

50 ARIA (for acetylcholine receptor-inducing activity), a protein purified on the basis of i

51 addition, neuregulin/acetylcholine-receptor-inducing activity, a nerve-derived factor that stimulate

52 We have mapped the location of otic placode-inducing activity along the rostrocaudal axis of the emb

53 We have investigated axis-inducing activities and cellular fates of the zebrafish

54 (INA), which exhibit a long-lasting defense-inducing activity and are fully dependent on the transcr

55 lation of maternal beta-catenin and its axis-inducing activity and can also inhibit the Gsk3beta -ins

56 terminal sequences are required for positive inducing activity and cytoplasmic localization, whereas

57 imultaneously increase the antiviral and Th1-inducing activity and decrease the antiproliferative act

58 This tissue also has heart-inducing activity and expresses mCer1 which, like its Xe

59 These data show for the first time that GVHD-inducing activity and GVL effects of allogeneic CD8 T ce

60 nificantly alters in vivo Ca(2+) oscillation inducing activity and in vitro interaction with PIP2 wit

61 heir function, inhibiting their neural crest-inducing activity and promoting ear formation.

62 olymorphonuclear neutrophil (PMN) chemotaxis-inducing activities, and IL-8.

63 T cells correlated inversely with their GVHD-inducing activity, and those of GKO donors were markedly

64 late that are absent in cyc mutants, whereas inducing activities are abolished by cyc, a mutation of

65 ctionation demonstrated that CCL2- and IL-12 inducing activities are biochemically distinct.

66 These inducing activities are separated into two distinct subo

67 al growth factor, and acetylcholine receptor-inducing activity) are known to induce growth and differ

68 Acetylcholine Receptor (AChR)-inducing activity (ARIA) is believed to be the trophic f

69 Acetylcholine receptor inducing activity (ARIA) is made by motoneurons and is r

70 AChR-inducing activity (ARIA)/heregulin, a ligand for erbB re

71 2 to rhHsp70-1 resulted in the same TNFalpha-inducing activity as observed with rhHsp70-2.

72 The collapse-inducing activity associated with B-class ephrins is lik

73 Here, we examined why the high levels of TNF-inducing activity associated with P. falciparum-parasiti

74 riable region retained substantial TNF-alpha-inducing activity at nanomolar concentrations.

75 d by AS sensitivity and maximal level of vir-inducing activity at saturating AS levels.

76 nuclear translocation, and the IFNA promoter-inducing activity but not the IRF-5-TRAF6 interaction.

77 both mAbs showed minimal intrinsic apoptosis-inducing activity, but each triggered potent apoptosis u

78 ptide of VdEG3 was sufficient for cell death-inducing activity, but this was not the case for the cor

79 erm daf-22 and dhs-28 cultures develop dauer-inducing activity by accumulating less active, long-chai

80 The cytokine-inducing activity by E. chaffeensis PBP provides novel i

81 microtubules, but rather enhances its pause-inducing activity by preventing KIF21B detachment from m

82 d for the optic vesicle to manifest its lens-inducing activity, by regulating downstream genes and/or

83 All AR-inducing activity coeluted with FSP.

84 addition, JA did not co-purify with the SAR-inducing activity confirming that JA is not the mobile s

85 urified heparin saccharides show that bypass-inducing activity correlates with distinct structures, p

86 ral endoderm subtype has much higher cardiac-inducing activity correlating with relatively enhanced l

87 he two AtMCPs revealed that their cell-death-inducing activities depend on their catalytic center cys

88 By inducing activity-dependent plasticity in the visual cor

89 This endocrine-inducing activity depends on inactivation of Notch.

90 cells, which lack IL-1alpha or another IL-8-inducing activity, did not release IL-8 after infection,

91 nocytogenes infection: (i) a direct cytokine-inducing activity encoded by the cholesterol-dependent c

92 y high levels of CD301b and have potent Treg-inducing activity ex vivo.

93 Moreover, ARN-509 lacked inducing activity for AR nuclear localization or DNA bin

94 The dominant portion of this IL-17-inducing activity for both CD4(+) and CD8(+) T cells is

95 in gene PA4467, was used to characterize the inducing activity from Burkholderia: Biochemical and gen

96 Moreover, the striated muscle inducing activity from midtransition iris and ciliary bo

97 olished PLC activity and [Ca2+]i oscillation-inducing activity from sperm extracts.

98 ng anti-IL-13 Ab removed most of the eotaxin-inducing activity from Th2 supernatants, although it did

99 The inducing activity from the lens acts only over short ran

100 ir cytotoxicity to cytoprotective heat-shock-inducing activity (HSA).

101 ophysical characterization of the human CD1d-inducing activity identified heat shock protein 110 (Hsp

102 nstrate that AID has promiscuous genomic DSB-inducing activity, identify homologous recombination as

103 aberrant signaling alterations and apoptosis-inducing activities in tumor samples.

104 Since 80% of the permeability-inducing activity in 9L-conditioned medium was removed b

105 s of tryptophan metabolites and plasma's AHR-inducing activity in ECs significantly increased the ris

106 Finally, comparisons of TNF-alpha-inducing activity in known low-, intermediate-, and high

107 or FcgammaRII Abs, could stimulate this IL-8-inducing activity in lymphocytes, suggesting that Fcgamm

108 but demonstrates a higher level of apoptosis-inducing activity in macrophages, compared with WT Cyt c

109 cause it correlated with calcium oscillation-inducing activity in mammalian eggs.

110 tochondria, wild-type p53 lost its apoptosis-inducing activity in neurons but not in non-neuronal cel

111 d the relationship between IS levels and AHR-inducing activity in sera of patients with ESRD.

112 activity in cool-sensitive fibers as well as inducing activity in tactile fibers, cold nociceptors an

113 correlate subcellular localization and gene-inducing activity in the presence of regulatory subunit

114 Approximately 50% of the observed TNF-alpha-inducing activity in the rhHSP60-2 preparation is due to

115 e macrophages and that the observed TNFalpha-inducing activity in the rhHsp70-2 preparation is entire

116 the prospective anterior hindbrain, had Pax8-inducing activity in this assay.

117 Although Bok-S retains the apoptosis-inducing activity in transfected cells, it has lost the

118 mily cytokine displaying selective apoptosis-inducing activity in transformed cells without harming n

119 emonstrated to have hepatocyte growth factor-inducing activity in vitro, but alone had no direct mito

120 ain key signature features in vitro and hair-inducing activity in vivo.

121 in (Cdc42ep4-l or Cep4l) has robust neuronal-inducing activity in Xenopus embryos.

122 Results of the mutants inducing activities indicated that several charged and h

123 3, was identical to native FoxD3 in mesoderm-inducing activity, indicating that FoxD3 functions as a

124 nt of CTNNBL1, suggesting that the apoptosis-inducing activity is a function of this region.

125 not apoptosis in HCC, and that the autophagy-inducing activity is associated with PP2A-regulated AMPK

126 -regulates the IL-8 receptor, show that this inducing activity is because of the presence of IL-8 in

127 idues are individually mutated, the necrosis-inducing activity is completely abolished.

128 This endoderm-inducing activity is dependent on the presence of the RN

129 nt to trigger cell death, no such cell death-inducing activity is found with RPW8.2 variants that con

130 The most potent inducing activity is localized to the dorsal neural tube

131 This flat-cell inducing activity is severely reduced by cotransfection

132 th the viral genome, but its heterochromatin-inducing activity is suppressed by mTOR-mediated phospho

133 ARIA (AChR inducing activity) is believed to be the trophic factor

134 led MARIA (muscarinic acetylcholine receptor-inducing activity) is produced by Muller glial cells in

135 inhibitors Dkk1 and crescent possess cardiac-inducing activities led to the contrary hypothesis that

136 unoregulatory cytokine with potent IFN-gamma-inducing activities, may play an important role in Th1-m

137 ation of a novel astrocyte-derived migration-inducing activity (MIA).

138 on of CD1d expression, with the maximum CD1d-inducing activity observed in the small intestine.

139 The TNF-alpha-inducing activities of both rhHSP60-2 and LPS with equiv

140 derstood are the cytotoxicity- and apoptosis-inducing activities of gp41CD as well as potential roles

141 h IVIG neutralize the mitogenic and cytokine-inducing activities of group A streptococcal (GAS) super

142 nscriptional transactivation and G(2) arrest-inducing activities of murine p53.

143 The TNFalpha-inducing activities of rhHsp-2, LPS alone, and LPS plus

144 s absolutely required for the OLIG2- and OLP-inducing activities of SHH.

145 us laevis embryogenesis is controlled by the inducing activities of Spemann's organizer.

146 izer-specific protein required for the trunk-inducing activities of Spemann's organizer.

147 tor-alpha-, interleukin-12- and nitric oxide-inducing activities of T.cruzi trypomastigote mucins wer

148 sed the cell growth inhibition and apoptosis inducing activities of the compounds.

149 Syncytium-inducing activities of the ELI viruses, especially when

150 idence that these IKKs mediate the NF-kappaB-inducing activities of these MEKKs.

151 o neutralize the proliferative- and cytokine-inducing activities of these superantigens was investiga

152 that the survivin-suppressing and apoptosis-inducing activities of YM155 involve its interaction wit

153 rogen linker was essential for the apoptosis-inducing activity of 4-anilinoquinazolines and substitut

154 FcgammaRIII appeared essential for apoptosis-inducing activity of a non-hepatotoxic anti-Fas mAb HFE7

155 t assay to determine the bystander apoptosis inducing activity of a panel of primary Envs.

156 dia specifically potentiates the mesendoderm-inducing activity of a subset of TGF-beta family members

157 ood with rBPI(21) potently inhibited the TNF-inducing activity of a variety of gram-negative bacteria

158 Finally, we show that the strong apoptosis-inducing activity of AA may stem from its ability to sel

159 ity, rBPI(21) consistently inhibited the TNF-inducing activity of all strains tested (IC(50), 1 to 1,

160 The TSLP-inducing activity of Alternaria was partially blocked by

161 CCAT1 as a potential mediator of the growth-inducing activity of ASH1L.

162 The broad-spectrum ICD-inducing activity of aspercyclicins, combined with their

163 The osteoclast inducing activity of BM plasma was tested in cell cultur

164 gene expression and chromatin accessibility, inducing activity of both the neurogenic transcription f

165 resent study, therefore, the differentiation-inducing activity of C. pneumoniae to monocytes was exam

166 The death-inducing activity of CC3 resides within its amino-termin

167 Blocking the apoptosis-inducing activity of CD30L by its soluble receptor may e

168 effects and graft-versus-host disease (GVHD)-inducing activity of CD8 T cells was compared in murine

169 retain the peripheral actin microspike (PAM)-inducing activity of Cdc42, interaction with PAK1 or WAS

170 timulated Mphi, contributed to the IFN-gamma-inducing activity of chitin.

171 ade of NADPH production aggravated the death-inducing activity of Dronc in specific neurons, but not

172 urified REJ, and purified REJ absorbs the AR-inducing activity of EJ.

173 Ps in FCS are largely responsible for the 2A-inducing activity of FCS and that Noggin may normally in

174 r, our results demonstrate that the cytokine-inducing activity of flagellins from gram-negative bacte

175 that headless Myo10 suppresses the filopodia-inducing activity of full-length Myo10.

176 tion with human serum enhanced the TNF-alpha-inducing activity of GBS in a C3- and factor B-dependent

177 focused on the estrogenic and proliferation-inducing activity of genistein.

178 teract the neurogenic but not the floorplate-inducing activity of Gli proteins.

179 We show that the cytokine-inducing activity of Helicobacter LPS was mediated by TL

180 We now provide evidence that the apoptosis-inducing activity of hPNPase(old-35) is mediated by acti

181 The senescence-inducing activity of IGFBP3 is inhibited by tissue-type

182 Further, the Th2-inducing activity of IL-12 antagonism is not related to

183 inhibit axial development and with the axis-inducing activity of its dominant-negative form (delta R

184 thermore, we demonstrate that the roof plate-inducing activity of Lmx1b can be suppressed by Mash1 (C

185 alpha and IKK-beta can mediate the NF-kappaB-inducing activity of MEKK1.

186 ich binds free beta-catenin, blocks the axis-inducing activity of membrane- tethered beta-catenin.

187 ably, the SOX9/ADAM17 axis dominated the TIC-inducing activity of miR-145.

188 level of FLAP in bcl-xL cells, the apoptosis-inducing activity of MK886, and the rapid loss of bcl-xL

189 Stress fiber-inducing activity of myocilin was blocked by antibodies

190 ne receptor Notch interferes with the muscle-inducing activity of myogenic bHLH proteins, and it has

191 d a complementation assay confirmed cytokine-inducing activity of native PBP.

192 ed for maintenance of acetylcholine receptor-inducing activity of nicotinic receptors in neurons and

193 We found that the neural and retina-inducing activity of Noggin requires Tbx3.

194 the planar structure and femtomolar rosette-inducing activity of one rosette-inducing small molecule

195 he generation of BM-DCs, amplifies the IL-23 inducing activity of PGE2 in a synergistic manner.

196 dependent protease resistance and conversion-inducing activity of PrPSc molecules in scrapie-infected

197 esence of a calpain inhibitor, the apoptosis-inducing activity of PS-341 was dramatically enhanced.

198 or MMP-2, but instead antagonized the MMP-1-inducing activity of purified native CD147.

199 unctional data for an AR-dependent apoptosis-inducing activity of RB and highlight the importance of

200 n the growth and tumor necrosis factor (TNF)-inducing activity of representative gram-negative clinic

201 oth the endotoxin activity and the TNF-alpha-inducing activity of rhHSP60-2 were essentially eliminat

202 ut inhibited only about 50% of the TNF-alpha-inducing activity of rhHSP60-2.

203 n medium essentially eliminated the TNFalpha-inducing activity of rhHsp70-2.

204 environmental factor that controls the death-inducing activity of RIPK1.

205 bsequent analysis revealed that the TNFalpha-inducing activity of salmonellae was associated with fla

206 This neural-inducing activity of Smad7 may be due to inhibition of B

207 he main component of the [Ca2+]i oscillation-inducing activity of sperm but provide evidence that the

208 Therefore, the apoptosis-inducing activity of T/t-common is related to its abilit

209 Consistent with the apoptosis-inducing activity of T/t-common, we found that T/t-commo

210 , but not the type II ZmMC9, suppress the HR-inducing activity of the autoactive NLR protein Rp1-D21

211 In contrast, the IFN-inducing activity of the baculovirus was unaffected by D

212 The apoptosis-inducing activity of the BH3 domains requires both membr

213 PKI are able to completely inhibit the gene-inducing activity of the catalytic subunit even when the

214 ls were extremely sensitive to the apoptosis-inducing activity of the compound in two-dimensional cul

215 than wild-type counterparts to the apoptosis-inducing activity of the compound, revealing its biologi

216 However, the cranial phenotype-inducing activity of the conditioned medium factor requi

217 in the literature we sought to test the axis-inducing activity of the embryonic shield.

218 Wnt signals are required for the inducing activity of the epidermis in chick and amphibia

219 Furthermore, the tumor-necrosis-factor-alpha-inducing activity of the lipopolysaccharides and the che

220 that auxin acts in the epidermis in part by inducing activity of the locally acting, growth-promotin

221 from 'Intestinal Inflammation Targets Cancer-Inducing Activity of the Microbiota' by Arthur et al. (2

222 n domain were required for full angiogenesis-inducing activity of the MMP-9 enzyme.

223 es the rat striatal neuronal differentiation-inducing activity of the N-terminal lipid.

224 Interestingly, the apoptosis inducing activity of the polyamine-depleted BAL fluids w

225 of flagellin is essential for the TNF-alpha-inducing activity of the protein.

226 thymocyte survival by repressing cell-death-inducing activity of the serine/threonine kinase RIPK1.

227 Optimal death-inducing activity of the spacer-RING required both the s

228 , which were absolutely critical for the IgG-inducing activity of the vaccine in mice.

229 d docetaxel treatment and that the NF-kappaB inducing activity of these agents was completely abrogat

230 owth in vivo; and inhibited the angiogenesis-inducing activity of these cells in vitro and in vivo.

231 o be responsible for the [Ca2+]i oscillation-inducing activity of these extracts.

232 The matrilysin-inducing activity of THP-1 conditioned medium was comple

233 Many studies have shown that the apoptosis-inducing activity of TRAIL can be enhanced by various ca

234 xpressed TrkC and facilitated the presynapse-inducing activity of TrkC in rat hippocampal neurons.

235 presence of Tsg enhances the secondary axis-inducing activity of two products of chordin cleavage.

236 , it is required for the endogenous mesoderm inducing activity of vegetal cells before gastrulation;

237 effect, completely inhibiting the apoptosis-inducing activity of wild-type VacA.

238 nize Wnt signaling, blocked the neural-crest-inducing activity of Wnt-3a in animal explants and inhib

239 expressing cells can reduce the dermomyotome-inducing activity of WNT1 and WNT4, but not that of WNT3

240 show that while XtSulf1 can enhance the axis-inducing activity of Wnt11, XtSulf1 acts during embryoge

241 al co-regulators, is essential for the XmyoD-inducing activity of Xhes6.

242 The neural inducing activity of Xnr3 can be inhibited by overexpres

243 interfered with the cell-killing (apoptosis-inducing) activity of niCKP or PFP (infectious CKP), eve

244 ivation in turn serves to limit E2F1's death-inducing activity.Oncogene advance online publication, 1

245 -CF2-TAD (4) showed improved differentiation-inducing activity over beta-CH2-TAD (3), whereas analogu

246 , while PLC activity and [Ca2+]i oscillation-inducing activity persisted until degradation of the fra

247 of GM-CSF is mediated by its interleukin-23-inducing activity rather than its role as a growth facto

248 studies have shown that these differences in inducing activity result from differences in the sensor

249 Moreover, the apoptosis-inducing activity segregated with the aqueous humor frac

250 duction have identified regionally localized inducing activities, signaling molecules, potential comp

251 gulation of protein processing, and mesoderm-inducing activity support the hypothesis that localized

252 azine, an FDA-approved drug with ferroptosis-inducing activity, synergistically induces ferroptosis a

253 e demonstrated that DMC has better apoptosis-inducing activity than celecoxib, albeit with undefined

254 e R30A mutant of p65 had much less NF-kappaB-inducing activity than media from cells expressing the w

255 vergence in both enzyme activity and defense-inducing activity that are intrinsically connected.

256 tion corepressor Ski and leads to its neural inducing activity through inhibition of bone morphogenet

257 vity efficiently inhibits TLR4 transcription-inducing activities, thus illustrating a simple means by

258 mouse eggs enabled their Ca(2+) oscillation inducing activities to be compared with wild-type PLCzet

259 this, presumably by deploying its curvature-inducing activity to provide membrane flexibility and st

260 We assigned proliferation-inducing activity to TMEFF2.

261 or their proteasome-inhibitory and apoptosis-inducing activities under in vitro and in vivo condition

262 The IL-8-inducing activity was associated with molecules of < or

263 MAP kinase inducing activity was dependent on CRAF dimerization.

264 The inducing activity was dependent on vascular endothelial

265 IFNalpha-regulated gene-inducing activity was detected in some SLE plasma sample

266 l-1alpha receptor antagonist, show that this inducing activity was due to the presence of Il-1alpha i

267 We found that the CGFD-inducing activity was not specific to female germ cell c

268 ed by cholesterol treatment but the cytokine-inducing activity was not, these activities appeared to

269 in that co-migrated with calcium oscillation-inducing activity was recently described by Parrington e

270 However, the SAR-inducing activity was reconstituted by mixing Avr PeXs c

271 These posterior cells exhibit trunk-inducing activity when transplanted into naive tissue.

272 in 4 (rLLO416-529) did not exhibit IFN-gamma-inducing activity, whereas it did bind to immobilized ch

273 ed PE still contained only low levels of TNF-inducing activity, which showed no evidence of instabili

274 he widest range of phytohormone and volatile inducing activity, which spanned maize (Zea mays), soybe

275 exhibits both immunogenicity and cell death-inducing activity, which was mutated to separate these t

276 We show that the M(2)-inducing activity, which we tentatively have called MARI

277 cover network states, with stimulation phase inducing activity with distinct spectral and spatial pro

278 r, transforming ScrC's repressing ability to inducing activity with respect to swarming.

279 plete loss of its transforming and NF-kappaB-inducing activities, without affecting receptor expressi