ライフサイエンスコーパス: inefficiency

1 w workload approach to prevent potential BCI-inefficiency.

2 hindered by their haematologic toxicity and inefficiency.

3 could be; a phenomenon we call metacognitive inefficiency.

4 or production use due to their computational inefficiency.

5 ation commonly considered a measure of brain inefficiency.

6 itions, as well as the first-cycle coulombic inefficiency.

7 ition, interference, or sequence-derived PCR inefficiency.

8 ging) contributes significantly to treatment inefficiency.

9 volve multiple steps that introduce bias and inefficiency.

10 ixed-model methods suffer from computational inefficiency.

11 alternative pathways that increase metabolic inefficiency.

12 hondrial proton gradient and cause metabolic inefficiency.

13 o adverse patient consequences, and provider inefficiency.

14 mere-specific DNA single-strand break repair inefficiency.

15 capture only partial information, leading to inefficiency.

16 subjects protection and incurs considerable inefficiency.

17 d noninvasive method to estimate ventilatory inefficiency.

18 against errors from photon loss and detector inefficiency.

19 ells is an important component of metastatic inefficiency.

20 gs is an important determinant of metastatic inefficiency.

21 lp low-affinity sites overcome their kinetic inefficiency.

22 uire large corrections for charge collection inefficiency.

23 this may lead to patient harm and procedural inefficiency.

24 educing food intake and increasing metabolic inefficiency.

25 h-charge overpotential that results in large inefficiencies.

26 vices sector and result in unintended system inefficiencies.

27 , is presented that overcomes these sampling inefficiencies.

28 rocesses, due to their current high cost and inefficiencies.

29 he continuum of care and creates substantial inefficiencies.

30 We show that this leads to considerable inefficiencies.

31 cians, and surgical staff to reduce systemic inefficiencies.

32 lenges, resulting in introduction delays and inefficiencies.

33 ther IRBs to begin identifying and improving inefficiencies.

34 ence clinical behavior and correct for these inefficiencies?

35 flexibility and motion, which cause packing inefficiencies and greater disorder of the protein layer

36 Inefficiencies and harms can arise if a biomarker hypoth

37 serine and methionyl-threonine CNBr cleavage inefficiencies and have developed a simple methodology t

38 drones) have the potential to reduce system inefficiencies and improve access to transplantation.

39 article, we suggest that, to overcome these inefficiencies and improve neuronal differentiation prot

40 onsense codons that are generated by routine inefficiencies and inaccuracies in RNA metabolism such a

41 create vast quantities of wastewater through inefficiencies and poor management of water systems.

42 to saponification, correcting for extraction inefficiencies and potential MS matrix enhancement or su

43 ctivities are low owing to carbon and energy inefficiencies and slow kinetics.

44 Multidisciplinary teams identified systemic inefficiencies and strategies to improve interdepartment

45 e profound implications for chemotherapeutic inefficiency and cancer relapse.

46 stence of different sources of metacognitive inefficiency and classify them into four categories base

47 ts reveals a mechanism underlying prefrontal inefficiency and cognitive deficits in schizophrenia, th

48 Metamorphic inefficiency and compositional relationships in the 1.2

49 from single cells to complex brains - create inefficiency and enhance modularity, leading to the diss

50 ons designed to help healthcare staff reduce inefficiency and improve quality, and have been implemen

51 DPD-mediated metabolic inefficiency and improvement of glucose homeostasis were

52 cessful, but the hospital stay was marked by inefficiency and inconveniences, as well as events that

53 water during wet conditions, this is also an inefficiency and is often detrimental to the environment

54 l stages, an observation consistent with the inefficiency and long latency of iPSC reprogramming.

55 re spending has generated both concern about inefficiency and policy debate about geographic-based pa

56 se of magnetic metals' optical loss, and the inefficiency and resistivity of semiconductor spin-based

57 pts SSM localization, promotes mitochondrial inefficiency and restricts maximal mitochondrial ATP-gen

58 ocedures in general, however, are limited by inefficiency and sequence biases.

59 astic, leading us to hypothesize that origin inefficiency and stochasticity are the result of a diffu

60 oke researchers aimed to identify sources of inefficiency and waste, recommend approaches to increase

61 terventions frequently demonstrate long-term inefficiency and weight regain.

62 resources but achieve lower accuracy (i.e., inefficiency) and that other patients with schizophrenia

63 which an estimated 30% is related to waste, inefficiencies, and excessive prices; health disparities

64 ough use of research designs known to reduce inefficiencies, and further research should be done to l

65 l to ameliorating the causes of many errors, inefficiencies, and reliability problems.

66 are inherently constrained by carbon, energy inefficiencies, and their roles in native metabolism, en

67 cental uric acid levels, prevented placental inefficiency, and improved fetal weights and serum trigl

68 er of factors contribute to nuclear transfer inefficiency, and we will review mouse cloning experimen

69 These inherent inefficiencies are attributed to (i) frictional losses r

70 In most other cases, inefficiencies arise due to unconstructive energy or cha

71 after peptic and tryptic digestion, showing inefficiency as a treatment to detoxify the gluten for c

72 n ECL2 provides a potential rationale to its inefficiency as an antagonist of CCR5 coreceptor activit

73 nt meta-analysis identified processing speed inefficiency as the largest single cognitive impairment

74 arbon-hydrogen (C-H) bonds would obviate the inefficiencies associated with generating halide precurs

75 ization must address the significant scaling inefficiencies associated with library handling and dist

76 The inefficiency associated with the refolding of reduced ma

77 initiation or elongation but rather relative inefficiencies at multiple steps.

78 dings indicate that AIE increases behavioral inefficiency, but not punishment-mediated risk-taking, i

79 In lean mice, DPD promoted metabolic inefficiency by increasing carbohydrate and fat oxidatio

80 This inefficiency can be overcome by increasing the amount of

81 pecific subsets of people, and the metabolic inefficiencies caused by these SNPs should be examined f

82 luster genes partially rescues reprogramming inefficiency caused by Snai1 depletion.

83 Maturation inefficiency could potentially reflect an evolutionary a

84 ion induced dissociation (CID) fragmentation inefficiency, developing sensitive liquid chromatography

85 ibraries in Escherichia coli, in particular, inefficiencies during digestion and ligation steps.

86 sertions, suggesting a significant degree of inefficiency during the integration process.

87 ternal fructose consumption led to placental inefficiency, fetal growth restriction, elevated fetal s

88 Both are common sources of failure and inefficiencies for these simulators.

89 Thus ERAD inefficiency for distinct aggregation-prone proteins can

90 of folding energy landscapes causes sampling inefficiencies however, particularly at low, physiologic

91 erythroid fate well before EPO acts, risking inefficiency if these progenitors are unneeded to mainta

92 is a means by which the HGE agent overcomes inefficiencies in acquisition of infection by ticks and

93 uplication (ITD), remains challenging due to inefficiencies in alignment of ITD-containing reads to t

94 There are inefficiencies in current approaches to monitoring patie

95 ups may be incomplete for others, leading to inefficiencies in decision making and growth in disparit

96 Addressing inefficiencies in diagnostic testing could minimize pote

97 cell level are poorly documented leading to inefficiencies in differentiation and concerns regarding

98 mind wandering in humans is characterized by inefficiencies in executive control (task-monitoring) pr

99 g TAC reduced anaplerotic flux, ameliorating inefficiencies in glucose oxidation, with energetic and

100 nt evidence of unacceptable inequalities and inefficiencies in health care.

101 ved as an essential component for addressing inefficiencies in healthcare.

102 Inefficiencies in high-risk infants later classified wit

103 n in agriculture and industry, and pervasive inefficiencies in its use.

104 ent myogenic cell lineages was confounded by inefficiencies in lineage marking and ablation.

105 the destruction of particles by weathering, inefficiencies in magnetic collection or separation tech

106 The greatest thermodynamic inefficiencies in photosynthesis occur during the conver

107 Inefficiencies in photosynthetic carbon assimilation can

108 e in the Protein Data Bank, largely owing to inefficiencies in protein production.

109 ined solid + fluid volume is reduced and the inefficiencies in space filling by the interpenetrated p

110 device as well as inform the mechanisms for inefficiencies in SWNTs and carbon based solar cells.

111 Accordingly, decades-long standing inefficiencies in targeted nuclear gene editing broadly

112 and temporal functions, probably reflecting inefficiencies in the adaptive interpretation of sensory

113 poorly cited articles and journals suggests inefficiencies in the cardiovascular research enterprise

114 For example, apparent inefficiencies in the cleavage of wood-specific H-bonds,

115 he current study maps the emergence of these inefficiencies in the first year of life.

116 t these gene products normally contribute to inefficiencies in the killing pathway.

117 ust be performed, which may actually lead to inefficiencies in the laboratory.

118 ead to inaccuracies of study information and inefficiencies in the process.

119 coverage has been reported, which indicates inefficiencies in the storage process.

120 drug susceptibility testing, high costs and inefficiencies in the supply of second-line drugs, and i

121 t of such immunogens is often complicated by inefficiencies in their production.

122 ting signals, certain stresses, or intrinsic inefficiencies in their translocation.

123 We also demonstrate inefficiencies in transcription initiation and elongatio

124 Inefficiencies in triaging, off-hour presentation, intra

125 ng to strong compensatory dietary responses, inefficiency in absorption of the energy they contain, a

126 d mice demonstrated a less mature phenotype, inefficiency in Ag uptake, and impaired migration in vit

127 with preschool asthma suggests its potential inefficiency in asthma studies at this age range.

128 Inefficiency in brain circuitry, defects in white matter

129 red within a few tens of thousands of years, inefficiency in carbon export to the deep sea lasted muc

130 rol the overall type I error) induces a core inefficiency in clinical trial productivity by reducing

131 timation of defective beans have shown their inefficiency in coffee value chain for large-scale analy

132 importance of population size and selection inefficiency in creating an evolutionary niche to promot

133 oid duplication of effort, slow adoption and inefficiency in development, those developing biological

134 esults indicate that spillover, a measure of inefficiency in dietary fat storage, is inversely associ

135 l is an important source of FFA and reflects inefficiency in dietary fat storage.

136 ogenous Wnt signalling underlies much of the inefficiency in directing hESCs towards specific cell ty

137 en analyzing a large number of genes and the inefficiency in exploiting prior knowledge, such as the

138 coming of nonlive vaccines is their relative inefficiency in generating T cell responses, thus limiti

139 ause there is considerable inconsistency and inefficiency in identifying those who would benefit from

140 -ND may partially compensate for the cardiac inefficiency in impaired beta-adrenergic signaling.

141 The lack of photoresolution was traced to inefficiency in intramolecular, through-bond triplet ene

142 th developmental dyslexia is how to separate inefficiency in learning on the one hand from exposure t

143 n-proteasome system function and only modest inefficiency in macroautophagy late in disease.

144 kinetic defects correlate with cardiomyocyte inefficiency in mitotic rounding, a process which is key

145 tive cardiolipin remodeling and bioenergetic inefficiency in myocardium rendered diabetic by streptoz

146 s, we suggest that ASD is associated with an inefficiency in optimizing network connections to achiev

147 e connections between neighboring areas, and inefficiency in pathways for emotions, and may help expl

148 ell receptor (TCR) signaling strength due to inefficiency in promiscuous expression of self-antigens

149 doplasmic reticulum (ER), we reveal a slight inefficiency in PrP signal sequence function that genera

150 nfluence to reduce other causes of waste and inefficiency in research.

151 ts application is limited by low potency and inefficiency in systemic delivery, especially failure to

152 Whether this reflects inefficiency in the ability of yeast actin to activate m

153 idely discussed illustration, are a cause of inefficiency in the allocation of resources across space

154 This increases inefficiency in the allocation system.

155 es in longer studies) can assist in reducing inefficiency in the current paradigm, which is still hea

156 elays are a major cause of economic loss and inefficiency in the growing industry of passenger flight

157 l resources in private sectors might produce inefficiency in the health care system and inequity in a

158 p I (NifS/IscS-like) paralogues results from inefficiency in the nucleophilic attack step associated

159 ty and specificity, thereby causing a severe inefficiency in the underlying multiple testing problem.

160 including (1) bias from temporal trends, (2) inefficiency in treatment effect estimation, (3) volatil

161 policy gives the greatest equity but causes inefficiency in unit bed-flow (0.5033 days).

162 a feedback cycle of electron transport chain inefficiency, increased reactive oxygen species producti

163 ules (e.g., ATP) but also triggers energetic inefficiency inside the cell.

164 k (i.e., Gibbs free energy of mixing) due to inefficiencies intrinsic to the process.

165 Such inefficiency is apparently due to competition between a

166 In part, the inefficiency is due to an absence of the coxsackie B and

167 c induction in the ferrocene system, and its inefficiency is explained by intramolecular coordination

168 concentrations in vivo and suggest that drug inefficiency is likely related to proteomic heterogeneit

169 metabolically inefficient, the source of the inefficiency is not from a primary function in thermogen

170 rom this +3 position beyond 8-oxoG, but this inefficiency is overcome by rapid extension of HiFi PolB

171 The intracellular source of inefficiency is postulated to be an increase in the ATP

172 A consequence of this inefficiency is that small numbers of transmitted founde

173 , this "female-specific crossover maturation inefficiency" is inferred to make major contributions to

174 te that the polymerase ribozyme, despite its inefficiency, is partially processive.

175 these tumor cells, often termed "metastatic inefficiency," is poorly understood.

176 This inefficiency leads to an increase in H3K9me2 at its targ

177 conform to established locales of prefrontal inefficiency linked to genetic risk for schizophrenia.

178 However, due to its computational inefficiencies, long run-time and complexity of various

179 , increased risk aversion) and/or allocation inefficiencies may have played a role.

180 by rs10748842, which does not fit the simple inefficiency model of risk association in DLPFC and sugg

181 Data were inconsistent with the neural inefficiency model.

182 Agricultural biotechnology is limited by the inefficiencies of conventional random mutagenesis and tr

183 Because of the inefficiencies of current formulation methods, materials

184 s (HCV) persistence in the host results from inefficiencies of innate and adaptive immune responses.

185 sidies, hostility to foreign investment, and inefficiencies of its state-planned economy underlie Ira

186 ic uncertainties of random mutations and the inefficiencies of nuclear transfer we directed our effor

187 ystem overcomes the small flow rates and the inefficiencies of previously described microfluidic and

188 Unfortunately, the workload and inefficiencies of primary care practice present barriers

189 te Carlo (ABC-SMC) help address the inherent inefficiencies of rejection sampling, such approaches ar

190 se they seemingly rid themselves of the many inefficiencies of sexual reproduction-the so-called cost

191 The catalytic inefficiencies of the CO2-fixing enzyme ribulose-1,5-bis

192 and widening, and it apparently reflects the inefficiencies of the U.S. private insurance-based, mult

193 These data suggest that the natural inefficiencies of transcription termination by the NS1 a

194 We conclude that the inefficiencies of unnatural AA-tRNA incorporations were

195 is physiological mechanism could explain the inefficiency of antitumor T cells in the tumor microenvi

196 Thus, the energy inefficiency of ATP production, despite high energy subs

197 ficient mice and further corroborated by the inefficiency of carbachol to increase IPSC frequency in

198 These results draw attention to the inefficiency of catechin to prevent actin oxidation, in

199 The complexity and inefficiency of chromatin immunoprecipitation strategies

200 ments, which could lead to marked failure or inefficiency of control strategies.

201 large part to the technical problems and/or inefficiency of conventional DNA transfer methods, as we

202 experience more frequent drought and flood, inefficiency of cropping systems water use will also inc

203 C) enzyme/prodrug strategy is limited by the inefficiency of cytosine deaminase (CD)-catalyzed conver

204 polbeta-knockout cell extracts is not due to inefficiency of damage incision but rather to deficiency

205 lopment of protein-based therapeutics is the inefficiency of delivery of protein cargo across the mam

206 ut limited by technical hurdles and profound inefficiency of direct gene transfer to the pancreas in

207 rect presentation, we show unequivocally the inefficiency of direct presentation and the essential re

208 The inefficiency of electron transfer in the TA sequence is

209 The inefficiency of gene transfer has greatly hindered gene

210 es from Ogt to investigate the basis for the inefficiency of hAGT in repair of m(4)T.

211 tor has been defined, in part because of the inefficiency of Histoplasma reverse genetics.

212 The inefficiency of HIV breast-milk transmission may be caus

213 itory receptors, which may contribute to the inefficiency of HIV-specific antibody responses.

214 ts by reverse genetics is constrained by the inefficiency of homologous recombination and by the diff

215 However, due to the relative inefficiency of homologous recombination in cultured hum

216 eted mutational analyses are hampered by the inefficiency of homologous recombination.

217 Despite the success of multiple groups, the inefficiency of in vitro reprogramming has made it chall

218 e in initiating therapeutic responses is the inefficiency of injection routes to deliver cells to the

219 The inefficiency of internalization of chemokine receptors i

220 ity of the SF gate appears to arise from the inefficiency of K(+) in stabilizing an active (i.e. cond

221 However, in contrast to the inefficiency of KSHV maturation following reactivation f

222 The inefficiency of lytic reactivation in various in vitro s

223 ical defects significantly contribute to the inefficiency of membrane protein folding in the cell.

224 hich likely contributes significantly to the inefficiency of metastasis formation.

225 One of the main reasons for the inefficiency of multicenter randomized clinical trials (

226 consequence of geographic isolation and the inefficiency of natural selection to eliminate harmful v

227 and practicability of viral vectors and the inefficiency of nonviral transfection techniques.

228 Inefficiency of oxidative phosphorylation can result fro

229 mplex I and supercomplex destabilization and inefficiency of oxidative phosphorylation.

230 Our results suggest that the inherent inefficiency of primer strand loop repair is not simply

231 ribution to conserving biodiversity, and the inefficiency of protected area systems is widely acknowl

232 often hampered by short ex vivo shelf life, inefficiency of recruitment to sites of inflammation, an

233 ly in tissue culture, in part because of the inefficiency of replication in cells.

234 has been underappreciated as a result of the inefficiency of ROS scavengers to control ROS bursts aft

235 to investigate possible transport defects or inefficiency of SMN associated RNPs in motor neuron axon

236 lem of animal genome engineering, namely the inefficiency of targeted DNA cassette insertion.

237 The inefficiency of the anaerobic pathway is compensated by

238 The immunological basis for the inefficiency of the cellular immune response in chronica

239 c CO(2) fixation in plants is limited by the inefficiency of the CO(2)-assimilating enzyme Rubisco.

240 The relative inefficiency of the complement-independent killing mecha

241 Additionally, our results expose an inefficiency of the enzyme in processing its radical int

242 lex virus-thymidine kinase assay support the inefficiency of the exonuclease as a "proofreading" acti

243 By reversing the energetic inefficiency of the failing heart, pharmacological XO in

244 ctive triphosphates is often hampered by the inefficiency of the first kinase-mediated step.

245 asculitic T cells expressed PD-1, suggesting inefficiency of the immunoprotective PD-1/PD-L1 immune c

246 equally large obstacle was presented by the inefficiency of the integration event when using traditi

247 at the introduction of the COMT overcame the inefficiency of the native pine methyltransferases for s

248 onally nonequivalent in vivo, with intrinsic inefficiency of the native PrP signal being required for

249 Yet the inefficiency of the ON cell is compensated by its presyn

250 cloning experiments, however, is the overall inefficiency of the process, typically 0-4%.

251 mperatures, arising because of the radiative inefficiency of the smallest grains, probably contribute

252 This feature appears to account for the inefficiency of the tRNA(SG)(Ala) promoter since provisi

253 to be both cause and effect of this partial inefficiency of the two-stage system, as confirmed also

254 rfering RNAs (siRNAs) as therapeutics is the inefficiency of their delivery across the plasma and end

255 The root cause of the catalytic inefficiency of TpCS may lie in the lack of protein flex

256 of Chlamydomonas is greatly hampered by the inefficiency of transgene expression from the nuclear ge

257 cost-effective alternative approach, but the inefficiency of transgene integration mandates ex vivo s

258 constraints, orientational effects, and the inefficiency of translational energy in promoting the re

259 These results indicate that inefficiency of type II-C Cas9 enzymes for genome editin

260 In spite of the inefficiency of unreduced pollen in unilateral sexual po

261 nditions (i.e., 0.1% at pH 7.0) explains the inefficiency of VanA in dipeptide synthesis.

262 The results also highlight the general inefficiency of whole-genome bisulphite sequencing, as 7

263 These observations suggest that the relative inefficiency of WT IKBKAP mRNA production from the mutan

264 iation from the 3/4 exponent suggests either inefficiency or compensating physiological mechanisms.

265 gth in the secondary dimension (tuning), the inefficiency or cross correlation between the two dimens

266 odeled as having three additional sources of inefficiency originating in the motor system, calculatio

267 ly if generalists must pay an extra cost, an inefficiency penalty, for their capacity to perform more

268 widely considered to be evidence of program inefficiency, policymakers need to understand how differ

269 elivery of health care is hindered by waste, inefficiencies, poor quality of services, and scarcity a

270 system have resulted in rapid cost increase, inefficiencies, poor quality, unaffordable health care,

271 ddition, within the high-risk infants, these inefficiencies predicted 24-month symptom severity.

272 tical next step is to establish whether this inefficiency predicts transition to stimulant dependence

273 that evolution might have worked around the inefficiency problem by fashioning a system capable of t

274 stence of different sources of metacognitive inefficiency provides an alternative explanation for beh

275 ical dyssynchrony associated with mechanical inefficiency, regional dysfunction, and RV dilatation is

276 fuel, but land-use requirements and process inefficiencies represent hurdles for large-scale deploym

277 Apart from the case with heterogeneity, inefficiencies result from the presence of strategic int

278 gene is inefficiently transcribed, and this inefficiency results from lack of a specific sequence wi

279 t understanding the sources of metacognitive inefficiency should be a primary goal of the science of

280 ypes using this approach is often plagued by inefficiency, slow conversion, and an inability to produ

281 bending or stretching processes, leading to inefficiency strain transfer.

282 dependently from other sources of perceptual inefficiency, such as the ability to filter out external

283 This relative inefficiency suggests a decreased ventilatory reserve an

284 Siblings and patients showed greater DLPFC "inefficiency" than controls.

285 sociated with physician rounding can produce inefficiencies that decrease time for essential activiti

286 sociated with physician rounding can produce inefficiencies that decrease time for essential activiti

287 ment is susceptible to design and procedural inefficiencies that hinder recruitment and to personnel

288 biodiversity, payment schemes must trade-off inefficiencies that result from over-simplified policies

289 ine deficient, probably by causing metabolic inefficiencies that should be detectable even while inge

290 o administer, taps an information processing inefficiency that is a central feature of the cognitive

291 Reduced mechanical inefficiency (the ratio of rate-pressure product to MVO(

292 explanation for the often-observed "frontal inefficiency," the failure to recruit prefrontal system

293 verse TCR repertoire by overcoming Vbeta RSS inefficiency to promote Vbeta recombination and alphabet

294 these results suggest induction of metabolic inefficiency under conditions of energy surfeit likely c

295 e serious drawbacks, such as safety hazards, inefficiency under in vivo-like conditions, and expensiv

296 We explored the impact of two potential 'inefficiencies': uneven net distribution among household

297 oxygen consumption decreased and ventilatory inefficiency (VE/VCO2 slope) increased with increasing s

298 text]e/[Formula: see text]co2), ventilatory inefficiency was closely related to PcCO2 (r values from

299 l compensation, capacity limitations, neural inefficiency) were examined in relation to working memor

300 flecting limbic interference with and neural inefficiency within the frontoparietal network.