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1 r DNA molecules (they can 'turnover', albeit inefficiently).
2 that in vitro activated PPO hydroxylates Tyr inefficiently.
3 w levels of occupancy use hospital resources inefficiently.
4 mediate the ELL2-P-TEFb interaction, albeit inefficiently.
5 he signal recognition particle were exported inefficiently.
6 approximately 50% of EBV genes are expressed inefficiently.
7 which is not made by C. albipes) was cleaved inefficiently.
8 sed, many existing algorithms perform rather inefficiently.
9 pha2-6 binding virus (NY18) that transmitted inefficiently.
10 Both LigD proteins seal DNA nicks, albeit inefficiently.
11 ispairs, which Polzeta4 alone made extremely inefficiently.
12 , whereas the F strain and R7910 reactivated inefficiently.
13 86D alteration was imported into the nucleus inefficiently.
14 ntly they initiate productive infection very inefficiently.
15 ment proteins enter and localize to the axon inefficiently.
16 overs transcripts with low expression levels inefficiently.
17 NA replication in met30 mutants, albeit very inefficiently.
18 reas poorly cytokinergic (PC) IgEs can do so inefficiently.
19 pathic (cp) BVDV induces IFN-alpha/beta very inefficiently.
20 methods typically require 24h and use target inefficiently.
21 oorly cytokinergic IgEs induce these effects inefficiently.
22 xpress much less CD1a molecules and function inefficiently.
23 and gp15 component glycopolypeptides, albeit inefficiently.
24 G1 (IgG1), D1-Fc, bound and neutralized HAV inefficiently.
25 eplication of this mutant RNA, although very inefficiently.
26 for the gp120-gp41 cleavage site but cleaved inefficiently.
27 mation and the catalytic machinery functions inefficiently.
28 es a sample classification algorithm working inefficiently.
29 traditional dimension reduction methods work inefficiently.
30 conditions, we found that TatE replaces TatA inefficiently.
31 er GPI proteins to cell wall beta1,6-glucans inefficiently.
32 le anionic and neutral cargoes are delivered inefficiently.
33 adjacent letters in a word, and combine them inefficiently.
34 ferric forms of Ent while IroE catalysed Ent inefficiently.
35 CCR5 conformation that the virus recognizes inefficiently.
36 st bNAbs neutralize 10-50% of HIV-1 isolates inefficiently (80% inhibitory concentration (IC80) > 5 m
38 ted by intestinal luminal compounds that are inefficiently absorbed and naturally present in foods.
39 ions in UL133-UL138(NULL) virus-infected ECs inefficiently acquired the virion tegument and secondary
42 activated in response to collagen or CRP and inefficiently adhere to and form thrombi on immobilized
46 with controls, DBA fibroblasts formed iPSCs inefficiently, although we obtained 1 stable clone from
48 like its cellular counterpart, secreted very inefficiently and can signal via vIL-6(2):gp130(2) signa
50 other IL-6 cytokines, vIL-6 is secreted very inefficiently and localizes in the endoplasmic reticulum
52 , unlike cellular IL-6 proteins, is secreted inefficiently and sequestered mainly in the endoplasmic
53 n cells (SCs) proliferate poorly, sort axons inefficiently, and cannot myelinate peripheral nerves.
55 latently infected trigeminal ganglia, albeit inefficiently, and most viruses that reactivated had a u
57 ts deficient in restriction were endocytosed inefficiently, and the levels of these mutants on the ce
58 een shown to catalyze processing, they do so inefficiently, and the oligomeric requirement for proces
59 cause RTEs may transduce homeostatic signals inefficiently, and their ability to survive is enhanced
60 -160 amino acids use the SRP pathway, albeit inefficiently, and therefore rely on Sec62 for efficient
63 th tandem repeats of the MREs are maintained inefficiently, as shown by both their decreased abilitie
64 These mRNAs were either not associated or inefficiently associated with polysomes in oocytes, and
65 that if Glu(441) is mutated, ADAMTS5 cleaves inefficiently at a proximate upstream site but normally
66 s, motor axons were error prone and wandered inefficiently at choice points within embryos, but parad
68 recursors are unstable and predicted to fold inefficiently at physiological pH and temperature, as ev
69 recent data suggest that Nfo protein cleaves inefficiently at some clusters, we tested whether polyam
74 The nucleoside triphosphate, 1-me-dATP, was inefficiently but actively demethylated by AlkB; a react
77 s to why incorrect dNTPs are incorporated so inefficiently by wt RB69 pol: (i) steric clashes with si
78 do show that the CGG-RNA is digested, albeit inefficiently, by the human Dicer enzyme, a step central
79 ted revelations: 1) Many RNA populations are inefficiently capped at steady state (~30 to 50%), and e
81 bsence of an ER export signal, molecules are inefficiently captured into coat protein complex II (COP
82 led the sup70-65 tRNA(Gln)(CUG) is unstable, inefficiently charged, and 80% reduced in its effective
83 cleotide triphosphate form, Fapy*dGTP, it is inefficiently cleansed from the nucleotide pool by the r
86 hus, the C-terminal-truncated apoE4 fragment inefficiently clears Abeta peptides and acts in concert
87 sulin and insulin, preproinsulin-A(SP24)D is inefficiently cleaved at an improper site, producing two
90 pyrimidinic endonuclease 1 (APE1) binds, but inefficiently cleaves, the AP for activation of vascular
91 ed here process small glucuronide substrates inefficiently compared to previously characterized L1 GU
92 nome-positive cells reactivated from latency inefficiently compared to wild-type and marker rescue vi
95 (Fe 2 (III/III)) form but is then only very inefficiently converted from the met to the active (Fe 2
96 , we observed that whole poxvirions are very inefficiently converted into MHC-II-binding peptides by
97 in darkness confirmed that the substrate is inefficiently converted to 14CO2, but both wild-type and
98 Further cleavage between R(200) and A(204) inefficiently converts the 76-kDa polypeptide to the mat
102 s studies have shown that nominal peptide is inefficiently cross-presented and that proteins and larg
106 s the presence of introns downstream of this inefficiently decoded UGA which confer the potential for
108 differentiation, leading to accumulation of inefficiently differentiated adipocytes with blunted exp
110 discriminate accumulators of carotenoids but inefficiently distribute them to some tissues and organs
112 items than are low capacity individuals, who inefficiently encode and maintain information about the
114 nd in the mouse silver mutant (hPmel17si) is inefficiently exported from the endoplasmic reticulum (E
115 elements in their 3' untranslated region are inefficiently exported to the cytoplasm and retained in
118 on with REF proteins, allowing the otherwise inefficiently exported viral mRNAs to access the TAP-med
119 s lacking functional splice sites, which are inefficiently exported, do not associate with nuclear sp
120 t to enhance RNA abundance from an otherwise inefficiently expressed intronless beta-globin construct
122 hat the error-prone DNA polymerase IV (Dpo4) inefficiently extended past the larger Peri:O(6)-BnG bas
123 lting proteasomes appear normal but assemble inefficiently, facilitating identification of assembly i
124 ylation, we found that genotype 3 HDAg-L was inefficiently farnesylated when expressed in the absence
125 heightened attention when the agent reached inefficiently for a goal object; in contrast, infants wh
129 e absence of ICP0, n212 and 7134 reactivated inefficiently from latently infected TG cells during cul
131 l models, a gE-null mutant infection spreads inefficiently from presynaptic neurons to postsynaptic n
133 urthermore, c-Myb-deficient progenitor cells inefficiently generate CD19(+) B-lineage cells during st
136 de processing assays suggested that TW10 was inefficiently generated after translocation to Nef, comp
138 pike genes of early human strains replicated inefficiently, HCoV-NL63 replicated for multiple passage
140 targeting signal (Delta 1,2 pre-F(1)beta) is inefficiently imported into mitochondria because it rapi
142 est that the twin arginine pathway functions inefficiently in BC202, likely due to the altered levels
143 bacteria, their natural hosts, they function inefficiently in eukaryotes, where lower free Mg(2+) con
146 enza A viruses (FluPolA) replicate viral RNA inefficiently in human cells because of species-specific
147 ts a restricted host range, replicating very inefficiently in many cell types, including human fibrob
148 e lambda Red recombination proteins function inefficiently in mycobacteria, illustrating the utility
149 eated by editing, but the C target is edited inefficiently in roots, and no NDH-D protein could be de
151 solar value, and show that stars formed very inefficiently in seven star-forming clumps in these gala
152 trimeric protein complex folds and assembles inefficiently in the endoplasmic reticulum (ER), which r
154 42 knockout melanoblasts migrated slowly and inefficiently in the epidermis, with nearly static pseud
157 thylthymine residues in DNA will be repaired inefficiently in vivo and therefore may occur at a low s
159 with PTCH1 and GAS1, but the variants do so inefficiently, in a manner that parallels their activity
160 latory target of Wnts and Igfs, GSK3beta, is inefficiently inactivated in male fin regenerates compar
163 importance, oligomerization-defective Hh is inefficiently incorporated into exovesicles due to its p
166 itions that involve plastid proteome changes inefficiently, indicating a requirement for reorganizati
168 of viral RNA at early times of infection and inefficiently induced SGs, suggesting the possibility th
174 ered to Ly6C(hi) monocytes, a cell type that inefficiently internalized L. monocytogenes With bone ma
176 Importantly, although LpdA is translocated inefficiently into cultured cells, an L. pneumophila Del
177 ERp29, a mutant ERp29 (D42A) that dimerizes inefficiently is unable to unfold polyomavirus or stimul
181 expressing the Pit1 receptor but could only inefficiently mediate infection of cells expressing the
182 ish that Stx5 is an autophagy target that is inefficiently membrane-targeted by alternative pathways.
183 in nutrient handling between efficiently and inefficiently metastasizing melanomas, with circulating
187 Collagen triple helices fold slowly and inefficiently, often requiring adjacent globular domains
188 apable of recognizing MVC-bound CCR5, albeit inefficiently on cells expressing physiologic levels of
190 For example, children who observe an adult inefficiently operating a novel object frequently engage
191 e-N2-dG and 1,N6-ethenoadenine adducts, very inefficiently opposite an acetylaminofluorene-adducted g
192 trates, such as the prion protein (PrP), are inefficiently or improperly translocated using only thes
194 wo familial AD (FAD)-linked PS1 variants are inefficiently packaged into transport vesicles generated
196 We demonstrate here that whereas RNase G inefficiently participates in the degradation of mRNAs a
197 y 1100delC and delE161 are both unstable and inefficiently phosphorylated at Thr68 in response to DNA
198 ral different cyclin-Cdk forms, but they are inefficiently phosphorylated in vivo without a cyclin-sp
199 eleased from the cell into the media and are inefficiently polymerized, resulting in fewer and misloc
202 horter (C(32)) alkyl chains are rapidly, but inefficiently, presented by cell surface CD1b proteins.
205 In addition, the Spt23pDeltaLPKY mutant is inefficiently processed and is defective at up-regulatin
206 ereas those potentially directed against the inefficiently processed and presented (cryptic) self epi
208 BCG-derived antigenic peptides are thus inefficiently processed by APCs, and we investigated alt
210 esize, and unlike longer RNAs, they are only inefficiently produced by in vitro transcription, especi
212 spliced and full-length viral mRNAs are very inefficiently recognized by the splicing machinery of th
213 Live imaging reveals that CMT2B proteins are inefficiently recruited to endosomes, but do not impair
214 lthough adoptively transferred Th2 cells are inefficiently recruited to the lung in response to Ag, c
216 refore whether corepressor is efficiently or inefficiently recruited to the resulting receptor-DNA co
217 nfected guinea pigs, HSV2-LAT-E1 reactivated inefficiently relative to the efficiency of its rescuant
222 ed DNA double-strand breaks (DSB), which are inefficiently repaired in PTEN-deficient astrocytes and
223 her find that only mutations that arise from inefficiently repaired lesions will accrue according to
224 esulting from replication fork collapse were inefficiently repaired, causing persistent DNA damage si
227 e silencing of PRC2-repressed genes that are inefficiently repressed at the level of chromatin, by ei
228 ADAMTS9 catalytic domain, and secretion was inefficiently restored by expression of the propeptide i
229 nnosidase were normal, although lvsB mutants inefficiently retained alpha-mannosidase, as well as two
230 nduction of reactive oxygen species that are inefficiently scavenged in K-ras mutant cells, leading t
232 expansion states: efficiently self-renewing, inefficiently self-renewing limited by apoptosis, exclus
234 BDNF(Val).BDNF(Met) heterodimers, which are inefficiently sorted into secretory granules resulting i
235 lated leader of P(R2)-derived transcripts is inefficiently spliced and apparently suppresses the outp
236 show that incompletely capped pre-mRNAs are inefficiently spliced at all introns, a fact that contra
237 ncreased splicing defects in mature RNAs are inefficiently spliced at the co-transcriptional level.
238 of the insertion: (i) the S.pombe intron is inefficiently spliced in S.cerevisiae due to the short d
240 rds an object or arched over an obstacle) or inefficiently (straight towards obstacle or arched over
242 gen delivery directly to skin DCs, which are inefficiently targeted by more conventional immunization
243 an intrinsic transcriptional terminator that inefficiently terminates HasS, permitting read-through t
245 t both Cys(82) and Cys(139) of CpeA but very inefficiently; the yield of PEB ligated at Cys(82) was m
248 ve that SHIP(-/-) stem/progenitor cells home inefficiently to bone marrow (BM), and consistent with t
249 n is that unmodified 'weak' tRNAs decode too inefficiently to compete against cognate tRNAs that norm
250 BLAST jobs that hitherto failed or slogged inefficiently to completion now finish with speeds that
256 of DI genomes as MDA5-deficient DCs respond inefficiently to Sendai virus stocks containing DI parti
257 ed (monomorphic) trypanosome strains respond inefficiently to SIF but can generate forms with stumpy
258 ch that their differentiated progeny respond inefficiently to signals to accumulate at sites of infla
259 udoreversion mutants were shown to bind very inefficiently to standard glycan microarrays containing
260 substrates, we found that RAG1 was recruited inefficiently to substrates lacking an RSS or containing
262 gastrulae, the cardiac precursors converged inefficiently to the heart fields and showed ectopic dis
264 i-targeting sequence, which cause FKRP to be inefficiently trafficked to the Golgi apparatus, did not
265 st common CF mutant is deltaF508-CFTR, which inefficiently traffics to the surfaces of most cells.
267 U6 promoter with a defective SPH element is inefficiently transcribed when injected into embryos.
268 event renders both alleles capable of being inefficiently transcribed; a second, less frequent event
269 trast, CD4+ T(CM) (CD45RO+ CCR7+ CD62L+) are inefficiently transferred and do not mediate EC injury.
271 w abundance when dietary MACs are scarce are inefficiently transferred to the next generation, and ar
272 y, while other nucleotides were not (or very inefficiently) transferred to the 3' ends of single-stra
273 most translation regulation is dedicated to inefficiently translated AU-rich mRNAs, whereas control
274 enomic replicon was subsequently found to be inefficiently translated in Huh7 cells compared to a typ
281 of control, suggesting that these lipids are inefficiently transported to droplets where the hydrolas
282 that the mitochondrial replicative helicase inefficiently unwinds well characterized intermolecular
284 have recently shown that canonical pathogens inefficiently use these host glycoproteins as a growth s
286 etable oils as PUFA sources that contain the inefficiently used C18 PUFAs rather than the operative C
288 defect in W349A could be trans-complemented inefficiently using BHK-REP cells (a cell line containin
293 that HtrA1 cleaves the WT FAS1-4 domain only inefficiently, whereas the amyloidogenic FAS1-4 mutation
294 Their predicted germline forms (gl) bind Env inefficiently, which may explain why they are not elicit
295 31, pHPV31-E6SD, -E6SA, and -E6IS replicated inefficiently while pHPV31-E6ID replicated at an interme
296 The full-length Spike protein functioned inefficiently with all three systems but was enhanced ov
298 re wild-type MHV-4 spike and associated only inefficiently with liposomes following incubation with s
299 vated from latently infected ganglia, albeit inefficiently, with the reactivating viruses having reve
300 osinase acquires copper only transiently and inefficiently within the trans-Golgi network of mouse me