ライフサイエンスコーパス: infected individual

1 e population of viruses within a chronically infected individual.

2 tivity to a V3 antibody and to serum from an infected individual.

3 umber of secondary cases resulting from each infected individual.

4 and are preferential viral targets in HIV-2-infected individuals.

5 iagnostic testing capability for identifying infected individuals.

6 effective in reversing latency in cells from infected individuals.

7 nding effective treatments available for HIV-infected individuals.

8 c application, we isolated ten mAbs from WNV-infected individuals.

9 idence of DRMinV transmission among recently infected individuals.

10 alternative to daily oral therapy for HIV-1-infected individuals.

11 ted ADCC were frequently identified in HIV-2-infected individuals.

12 and post-exposure therapy with NiV- and HeV-infected individuals.

13 to disrupted host metabolite profiles in HIV-infected individuals.

14 l hepatitis occurs in a very small number of infected individuals.

15 nsity dependence and the role of chronically infected individuals.

16 and host metabolites have been noted in HIV-infected individuals.

17 ic analysis of single plasmablasts from DENV-infected individuals.

18 ng and monitoring for drug resistance in HIV-infected individuals.

19 nitive disorders prevail in 20-50 percent of infected individuals.

20 ght facilitate risk assessment of CHD in HIV-infected individuals.

21 through the CCR6-CCL20 axis in treated HIV-1-infected individuals.

22 rythrocytes to the vasculature or tissues of infected individuals.

23 crophages are the main producers of HIV-1 in infected individuals.

24 ility to suppress HIV-1 replication in HIV-1-infected individuals.

25 stocks and patient plasma samples from HIV-2-infected individuals.

26 herapies and insufficiencies in treating HIV-infected individuals.

27 NAs that target HIV across a large number of infected individuals.

28 as significantly associated with T2DM in HIV-infected individuals.

29 and inflammation to the onset of HAND in HIV-infected individuals.

30 , including parasites isolated directly from infected individuals.

31 udes equivalent to what is observed in HIV-1-infected individuals.

32 obtained by bronchoalveolar lavage of HIV-1-infected individuals.

33 and those undergoing treatment for HIV in co-infected individuals.

34 ther cell subsets in a cohort of 29 Thai HIV-infected individuals.

35 fore represent a major barrier to curing HIV-infected individuals.

36 nd lymph node CD4(+) T cells from five HIV-1-infected individuals.

37 ing the efficiency of viral control in HIV-1-infected individuals.

38 %) and DRMinVs in 84 (10.1%) of the recently infected individuals.

39 parasite mortality, and migratory culling of infected individuals.

40 hat these clones are both represented in HIV-infected individuals.

41 cial systems by active spreading behavior of infected individuals.

42 by Candida spp. in HIV-infected and non-HIV-infected individuals.

43 in monocytes from untreated and treated HIV-infected individuals.

44 ells were purified from the blood of 7 HIV-1-infected individuals.

45 -restricted cellular immune responses in HIV-infected individuals.

46 be large benefits to vaccinating previously infected individuals.

47 at Cx43 is dysregulated in the hearts of HIV-infected individuals.

48 M. tuberculosis-specific CD4 T cells in HIV-infected individuals.

49 lowing clearance of peripheral virus in ZIKV-infected individuals.

50 oint host/pathogen genetic data from 541 HIV infected individuals.

51 high rates of cardiovascular disease in HIV-infected individuals.

52 ic improvement in the efficiency of locating infected individuals.

53 ains and detection in cerebrospinal fluid of infected individuals.

54 flammation and neurological disorders in HIV-infected individuals.

55 h clinical outcomes of malaria in Plasmodium-infected individuals.

56 ent an opportunity to improve care for HIV-2-infected individuals.

57 d CD4+ T cells from virally suppressed HIV-1-infected individuals.

58 ecting probably no more than 1 in 1,000 such infected individuals.

59 y, revealing the presence of salivary IgA in infected individuals.

60 euroinflammatory environment observed in HIV-infected individuals.

61 ections and providing the best treatment for infected individuals.

62 terruption (ATI) in the vast majority of HIV-infected individuals.

63 the properties of EVs from the semen of HIV-infected individuals.

64 tistically with the disturbed microbiomes of infected individuals.

65 -B alleles, HLA-B*52:01, present in 22.5% of infected individuals.

66 ponses to SARS-CoV-2 can be detected in most infected individuals 10-15 d after the onset of COVID-19

67 We identified 13 infected individuals (4.2% of those genotyped) responsib

68 potency of neutralization observed in these infected individuals, a combination of three subtype B E

69 studied human immunodeficiency virus (HIV)-1-infected individuals aged at least 15 years and prospect

70 tes to loss of immune control of LTBI in HIV-infected individuals, although the precise mechanisms wh

71 ted RSV genomic variation within and between infected individuals and assessed its potential utility

72 he existence of both acutely and chronically infected individuals and by seasonally changing transmis

73 n peripheral blood of virally-suppressed HIV-infected individuals and healthy controls stratified by

74 gical information, and genomic analyses from infected individuals and hundreds of ancient human sampl

75 ) memory T cells from virally suppressed HIV-infected individuals and in an in vitro primary cell mod

76 active disease occurs in only a fraction of infected individuals and is predicted by an elevated typ

77 ights the persistent defects in MBC from HIV-infected individuals and points to the PI3K signaling pa

78 valent in human immunodeficiency virus (HIV)-infected individuals and sexually active populations at

79 ervoir could have great implications for HIV-infected individuals and should be taken into considerat

80 examples of a phenomenon that is seen in all infected individuals and that is a major barrier to curi

81 tanding the pattern of integration events in infected individuals and therefore bears important clini

82 stinguish between disease states in HIV-1 co-infected individuals, and combinations of biomarkers are

83 lain and quantify diversity within and among infected individuals, and discuss advances that can be o

84 those, IL-18 is found highly upregulated in infected individuals, and its expression correlates with

85 ockdowns, tracking, tracing and isolation of infected individuals, and social distancing measures.

86 h the fecal-oral route, shed in the stool of infected individuals, and spread either by direct contac

87 presence of baseline RASs among genotype 1a-infected individuals, and the treatment phase was accomp

88 nti-HIV-1 gp120 mAbs have been isolated from infected individuals, and there is considerable interest

89 Although over 90% of infected individuals are asymptomatic or manifest noncri

90 Human immunodeficiency virus (HIV)-infected individuals are at increased risk of chronic ki

91 Human immunodeficiency virus (HIV)-infected individuals are at increased risk of cirrhosis

92 Many bnAbs isolated from HIV-1-infected individuals are encoded by immunoglobulin gene

93 We find that 2.9% of infected individuals are hospitalized and 0.5% of those

94 for plasma biomarkers to predict which HIV-1-infected individuals are likely to progress to active di

95 Specific antiviral medical treatments for infected individuals are not available.

96 age of the outbreak, i.e., a small number of infected individuals are responsible for large numbers o

97 ble at population-level (i.e., the number of infected individuals at a finite set of discrete times o

98 his approach in a longitudinal cohort of HIV-infected individuals before and during ART, we demonstra

99 In Fiebig stages II/III and in chronically infected individuals, beta7high cells were enriched in i

100 es aiming for malaria elimination, travel of infected individuals between endemic areas undermines lo

101 In some HIV-1-infected individuals, bnAbs evolved from precursor antib

102 munity is protective in the vast majority of infected individuals but can become detrimental if not f

103 py (ART) suppresses viral replication in HIV-infected individuals but does not eliminate the reservoi

104 (TAF) improves renal tubular markers in HIV-infected individuals but the impact on estimated glomeru

105 heat pulses enhanced thermal tolerance among infected individuals, but the magnitude of the parasitis

106 int prevalence of ART coverage among all HIV-infected individuals by age, sex, and year.

107 rP(Sc)) that self-propagates in the brain of infected individuals by converting the normal prion prot

108 from acutely (Fiebig I-III) and chronically infected individuals by sorting memory CD4+ T-cell subse

109 Most co-infected individuals can achieve a sustained HCV virolog

110 Recent research suggests that SARS-CoV-2-infected individuals can be highly infectious while asym

111 ity to acute viral infections in chronically infected individuals can be partly due to poor T-cell re

112 ger incubation periods, such as Ebola, where infected individuals can travel farther before becoming

113 or identifying antigen-specific MBC from HIV-infected individuals compared to healthy controls.

114 increase in plasma levels of CCL18 in HIV-1-infected individuals compared to uninfected controls (p

115 lizing antibody titers against DENV2 in ZIKV-infected individuals compared with uninfected controls a

116 fic CD4 T cells was markedly impaired in HIV-infected individuals, compared with HIV-uninfected indiv

117 Samples from 30 untreated, HIV-1-infected individuals demonstrated robust HIV Ag/Ab Combo

118 ate are relatively ineffective in cells from infected individuals despite activity in model systems.

119 human immunodeficiency virus type 1 (HIV-1)-infected individuals despite sustained antiretroviral th

120 tality in human immunodeficiency virus (HIV)-infected individuals despite treatment with antiretrovir

121 viruses persist in the CD4(+) T cells of HIV-infected individuals despite years of combination antire

122 to HIV envelope antigens, a minority of HIV-infected individuals develop a cognate polyclonal humora

123 A small number of HIV-1-infected individuals develop broadly neutralizing antibo

124 H. pylori to understand how only a subset of infected individuals develop cancer.

125 nfection rates, only a fraction of H. pylori-infected individuals develop gastric cancer.

126 HIV-infected individuals developing cryptococcal meningitis

127 parasites is a key determinant of whether an infected individual develops fever.

128 A subset of HIV-infected individuals develops such antibodies, but it is

129 lmost invariably leads to rebound viremia in infected individuals due to a long-lived latent reservoi

130 lls that can be found in lymphoid tissues in infected individuals during ART.

131 hat defective proviruses that persist in HIV-infected individuals during suppressive cART are transla

132 shows that a slowdown in the number of newly infected individuals during the expansion phase allows o

133 T cells isolated from virally suppressed HIV-infected individuals enable obtaining large numbers of c

134 ty to isolate unstimulated latent cells from infected individuals enables previously impossible studi

135 sequencing virus populations from naturally infected individuals enrolled in a prospective, communit

136 Despite these hurdles, a subset of HIV-infected individuals eventually develop broadly neutrali

137 ing analysis revealed that EV fractions from infected individuals exhibit a broader and more diverse

138 ether, our data suggest that SP EVs from HIV-infected individuals exhibit unique miRNA signatures and

139 rthermore, it is estimated that up to 80% of infected individuals experience mild symptoms or are asy

140 Most infected individuals experience mildly symptomatic coron

141 Interestingly, dysfunctional Tfh from HIV infected-individual fail to regulate the ADA pathway.

142 mumps virus whole genome sequences from 201 infected individuals, focusing on Massachusetts universi

143 We screened a plasma sample set of infected individuals followed up at four, 12 and 21 mont

144 We included 714 HIV-1 infected individuals, followed up at the University Hosp

145 l tracked human immunodeficiency virus (HIV)-infected individuals for 10 years following ART initiati

146 ZIKV RNA is detectable in blood and semen of infected individuals for weeks or months, during which s

147 We considered 313 HIV-infected individuals for whom reliable estimates of infe

148 CDRH2 that was isolated from the chronically-infected individual from whom the bent CDRH3 bNAbs were

149 ribe a cohort with a majority of HIV C-clade-infected individuals from Delhi, India, where HLA-B*52:0

150 escence-based detection of seroconversion in infected individuals from less than 1 ul of blood, and a

151 s collected from 70 virally suppressed HIV-1-infected individuals from Rakai District, Uganda, who ha

152 In infected individuals, G614 is associated with lower RT-P

153 ath among human immunodeficiency virus (HIV)-infected individuals globally.

154 HIV-infected individuals had a higher proportion of total at

155 he time at which the growth in the number of infected individuals halts and starts decreasing cannot

156 ological sex on disease progression in HIV-1-infected individuals has been focused on the chronic sta

157 HIV-infected individuals have excess congestive heart failur

158 Asymptomatically infected individuals have lower parasite densities on av

159 ection and enhance existing immunity in HCMV-infected individuals (HCMV+).

160 In our cohort of HIV-infected individuals HCV/HIV co-infection, older age, al

161 n is naturally achieved in less than 0.5% of infected individuals (here termed 'elite controllers'),

162 or blood plasma samples collected from HIV-2-infected individuals.IMPORTANCE An accurate picture of v

163 ber of secondary infections generated by one infected individual in a community in which everyone is

164 The odds ratio for identifying an infected individual in a household at a predicted high r

165 ating antigen concentration distributions in infected individuals in a population in which malaria is

166 unity considerably because the proportion of infected individuals in groups with the highest contact

167 CoV-2 in China, we generated 53 genomes from infected individuals in Guangdong using a combination of

168 ve therapy (IPT) reduces mortality among HIV-infected individuals in high-burden settings, but has re

169 irus from a large population-based sample of infected individuals in Rakai District, Uganda, reconstr

170 s always a large percentage of subclinically infected individuals in the population who will eventual

171 a cluster of neurosyphilis cases among HIV-1-infected individuals in Vermont in 2017-2018.

172 that recapitulates the symptoms observed in infected individuals, including bloody diarrhea.

173 resent immunodominant T cell epitopes in HIV-infected individuals, indicating the importance of furth

174 Semen EV fractions from acutely infected individuals induced a more proinflammatory sign

175 In cells from infected individuals, inhibition of HSF1 attenuated late

176 Multidimensional scaling separated HIV-infected individuals into 2 microbiome clusters, dominat

177 terferon for Treatment of Acute HCV in HIV-1 Infected Individuals is an open-label, 2-cohort, Phase 1

178 viral therapy (ART) discontinuation in HIV-1-infected individuals is believed to originate from a sma

179 antiretroviral therapy (ART)-suppressed HIV-infected individuals is critical for characterizing the

180 f population-wide restrictions, isolation of infected individuals is key to curtailing transmission.

181 Increased infectiousness of HIV-infected individuals is likely not an important driver o

182 se of hospitalization among Plasmodium vivax-infected individuals, leading to life-threatening anemia

183 sma-derived EVs from both uninfected and HIV-infected individuals, little is known about the properti

184 flow virometry to identify, in plasma of HIV-infected individuals, macrophage- and T-cell-derived HIV

185 ted from extracellular vesicles in sera from infected individuals may provide a new tool for diagnosi

186 entitled "Obesity and Fat Metabolism in HIV-infected Individuals." Mechanisms relating to adipose dy

187 evelopment of an adaptive immune response in infected individuals.METHODSWe studied 509 patients conf

188 at could compromise the health status of HIV-infected individuals might not be ethically warranted.

189 sis (MTB), with the overwhelming majority of infected individuals not developing disease (latent TB i

190 and affordable diagnostic tests to identify infected individuals, not all of whom are symptomatic.

191 opy numbers, and six key cytokines in 41 HIV-infected individuals off combination anti-retroviral the

192 telomere erosion, and cell apoptosis in HIV-infected individuals on antiretroviral therapy (ART).

193 -characterized clinical specimens from HIV-1-infected individuals on antiretroviral therapy (ART).

194 y in which 15 virologically suppressed HIV-1-infected individuals on antiretroviral therapy received

195 he inducible reservoir found in blood of HIV-infected individuals on antiretroviral therapy.

196 tration of immune checkpoint blockers to HIV-infected individuals on ART may facilitate latency disru

197 Five HIV-1-infected individuals on ART were studied, four of whom p

198 Chronically infected individuals on ART with no detectable plasma HI

199 NA in resting CD4+ T cells isolated from HIV-infected individuals on ART, demonstrating the potential

200 r contributors to the viral reservoir in HIV-infected individuals on ART.

201 We recruited 68 influenza-infected individuals on average 3.5 days after the onset

202 Human immunodeficiency virus-infected individuals on cART (predominantly containing t

203 t macrophages are a viral reservoir in HIV-1-infected individuals on effective ART and that M-tropic

204 l trial that randomly included 42 HIV type 1-infected individuals on effective cART: 20 who switched

205 emory (TCM) CD4+ T cells isolated from HIV-1-infected individuals on suppressive therapy.

206 nt phagocytosis assays use IE collected from infected individuals or from in vitro cultures of P. fal

207 rcoma (KS), an AIDS-defining cancer in HIV-1-infected individuals or immune-suppressed transplant pat

208 veloped using sequences from chronically HIV-infected individuals or uncommon HIV subtypes or were op

209 ibodies (bnAbs) develop in a subset of HIV-1 infected individuals over 2-3 years of infection.

210 of E. histolytica is the cyst, with a single infected individual passing up to 45 million cysts per d

211 ilities, a map that showed the number of HIV-infected individuals per km(2), and an impedance map.

212 ronically human immunodeficiency virus (HIV)-infected individuals, perturbations in memory CD4 T cell

213 In HIV-1-infected individuals, plasma viral loads were monitored

214 ses are often associated with high number of infected individuals (prevalence) and high pathogen load

215 The unhealthy ecostates of infected individuals progress towards the healthy ecosta

216 Serial specimens from a trial of HIV-infected individuals receiving antiretroviral treatment

217 MD) reduction in a population of Ugandan HIV-infected individuals receiving long-term antiretroviral

218 etroviral therapy in recently identified HIV-infected individuals reduces viral replication and decre

219 ution with antiretroviral therapy (ART), HIV-infected individuals remain highly susceptible to tuberc

220 Lung cancer incidence in HIV-infected individuals remained elevated >5 years after sm

221 Elimination of HIV DNA from infected individuals remains a challenge in medicine.

222 Infected individuals report a range of symptoms from hea

223 2 and 0.81 to 0.85 in HIV-uninfected and HIV-infected individuals, respectively.

224 in SARS-CoV-2 spread, with between 2-10% of infected individuals resulting in 80% of secondary infec

225 Lymph node cells from untreated HIV-infected individuals revealed that TFR cells harbored th

226 alizing antibodies (bNAbs) isolated from HCV-infected individuals, revealed a disulfide bond-containi

227 unique spectrum of disease depending on the infected individual's age and immunity.

228 + T lymphocytes and viral load (only for HIV-infected individuals), salivary cytokines (interleukin,

229 to promote transmission of the organism, as infected individuals shed many litres of diarrhoeal flui

230 Although most herpes simplex virus 1 (HSV-1)-infected individuals shed the virus in their body fluids

231 Persons living with ZIKV-infected individuals should be a focus of public health

232 The L. wallacei-infected individuals showed reduced lifespan and morphol

233 ver, it is estimated that up to 50% of HIV-1 infected individuals still develop HIV-1 associated neur

234 /Tc9 cells in S. stercoralis infection in 15 infected individuals stimulated with parasite antigen fo

235 tudies in human immunodeficiency virus (HIV)-infected individuals suggest excess weight gain with int

236 terferon for treatment of acute HCV in HIV-1 infected individuals (SWIFT-C) is an open-label, 2-cohor

237 One difficulty is that P. knowlesi infected individuals tend to present with low parasitaem

238 ia parasites is understudied, partly because infected individuals tend to present with low parasite d

239 A subset of HIV-infected individuals termed elite controllers (ECs) main

240 A CN declined significantly faster among HIV-infected individuals than among HIV-uninfected persons (

241 A CN declines significantly faster among all infected individuals than among HIV-uninfected persons.

242 HIV-1-infected individuals that develop exceptionally strong b

243 T cells isolated from virally suppressed HIV-infected individuals that recapitulates HIV-1 latency an

244 tuberculosis (TB) is a risk factor in HIV-1-infected individuals, the mechanisms by which Mycobacter

245 In a subset of HIV-1C-infected individuals, the tetrapeptide insertion PYxE ha

246 ell-matched mucosal antibodies in previously-infected individuals, there can exist protection against

247 Since NK cells were from non-HIV-infected individuals, they model the consequences of hea

248 ) and infectivity (i.e. the propensity of an infected individual to transmit disease).

249 ipitously from ~3.5 secondary infections per infected individual to ~1 at present.

250 e from healthy unexposed and previously MARV-infected individuals to assess if naive repertoires cont

251 ss of these immune cells, therefore allowing infected individuals to better fight the infection.

252 nding of antibodies within plasma from HIV-1-infected individuals to early-stage infected cells expre

253 nhancing care and treatment among HCV/HIV co-infected individuals to Eliminate Hepatitis C transmissi

254 ufficient amounts of CD4(+) T cells from HIV-infected individuals to interrogate the HIV reservoir in

255 suppresses HIV-1 replication and enables HIV-infected individuals to live long, productive lives.

256 r to maximize the transmission of virus from infected individuals to uninfected individuals.IMPORTANC

257 Among drug-naive HIV-infected individuals treated with InSTI-based regimens,

258 The existence of HIV reservoirs in infected individuals under combined antiretroviral thera

259 re, we show, using penile tissues from HIV-1-infected individuals under suppressive combination antir

260 f intact and defective proviruses in 3 HIV-1-infected individuals undergoing long-term antiretroviral

261 resting CD4(+)T cells isolated from aviremic infected individuals upon cell stimulation with latency

262 and potency of NAb responses in 98 CRF07_BC-infected individuals using a large, multi-subtype panel

263 proteome arrays from chronic untreated HIV-1-infected individuals using the classificatory random for

264 Here, we evaluate genetic similarity between infected individuals using three indices: sharing of par

265 the calculation of transmission links among infected individuals using threshold-based methods.

266 Among the C-clade-infected individuals, we show that HLA-B*52:01 is the mo

267 Using CD4(+) T cells from HIV-infected individuals, we show that the engagement of PD-

268 ntaining CDRH3 is specific to particular HCV-infected individuals, we solved a crystal structure of t

269 e individuals and one from a previously MARV-infected individual were selected for testing as HCDR3 l

270 Viral sequences from infected individuals were grouped into 3 distinct cluste

271 collected from highly microfilaremic Loa loa-infected individuals were largely misidentified as Oncho

272 was followed by intervention (i.e., culling infected individuals), whereas current methods of molecu

273 tibodies (MAbs) from B cells of a single HCV-infected individual who cleared one genotype 1a infectio

274 plored in human immunodeficiency virus (HIV)-infected individuals who began antiretroviral therapy (A

275 ment of hepatitis C in majority of currently infected individuals who can be easily cured and optimiz

276 HIV-infected individuals who had lower CD4+ T-cell counts (P

277 een participants who were uninfected and HIV-infected individuals who had well-controlled HIV levels.

278 ca where Chagas disease is endemic and among infected individuals who have migrated to nonendemic are

279 V RNA-derived nef clones from 30 acute/early-infected individuals who participated in a clinical tria

280 Superspreaders, infected individuals who result in an outsized number of

281 To reach 90% coverage, many HIV-infected individuals (who have yet to initiate treatment

282 nt of coronavirus disease 2019 (COVID-19) in infected individuals, who can either exhibit mild sympto

283 influenza vaccination being impaired in HIV-infected individuals with a CD4+ T-cell count of <200 ce

284 Genotype 1a-infected individuals with baseline RASs and genotype 4-i

285 y-chain repertoires in a large cohort of HIV-infected individuals with bNAb responses or no neutraliz

286 We analyzed gut microbiota in 30 HIV-infected individuals with CHD (CHD+) and 30 without CHD

287 (ART) in human immunodeficiency virus (HIV)-infected individuals with cryptococcal meningitis places

288 Studies treating HIV-1-infected individuals with latency reactivation agents to

289 is recommended for TB diagnosis among HIV co-infected individuals with low CD4 T-cell counts.

290 rk City, we report that the vast majority of infected individuals with mild-to-moderate COVID-19 expe

291 ndividuals with baseline RASs and genotype 4-infected individuals with prior failure of HCV treatment

292 al blood mononuclear cells isolated from HIV-infected individuals with suppressed infection.

293 ears of age, mtDNA CN is similar between HIV-infected individuals with well-controlled HIV and uninfe

294 6 units of change/year; P = .04), even among infected individuals with well-controlled HIV.

295 rom Mycobacterium tuberculosis-infected (Mtb-infected) individuals with and without HIV coinfection.

296 types that differ 100-fold in viral titer in infected individuals, with similar differences observed

297 dependent t-tests were used to compare HIV-1-infected individuals within or outside an identified clu

298 trolled immunologically in a small subset of infected individuals without antiretroviral therapy (ART

299 health problem with 257 million chronically infected individuals worldwide, of whom approximately 20

300 sting coverage of 70%, and the time that HIV-infected individuals would need to spend travelling in o