ライフサイエンスコーパス: infection

1 otspots (RACD events yielding >=1 additional infection).

2 ation and tissue repair in the resolution of infection.

3 pTh1 cell loss and exhaustion during malaria infection.

4 lymphomagenesis during chronic Helicobacter infection.

5 inished abilities to block host responses to infection.

6 rance in the spleen during a murine systemic infection.

7 mbled findings reported in patients with NiV infection.

8 d efficacy in a murine model of lethal HSV-2 infection.

9 bling the virus to successfully establish an infection.

10 d with the risk of contracting a bloodstream infection.

11 or negatively influence host survival during infection.

12 midine salvage during the earliest stages of infection.

13 onent of the innate immune response to viral infection.

14 PIV-mediated protection against C. burnetii infection.

15 al shortening were observed eight weeks post infection.

16 h the later development of secondary Candida infection.

17 of exhausted CD4(+) T-cell memory in chronic infection.

18 sponses than were seen with wild-type icPEDV infection.

19 ave rapidly evolved to resist or tolerate Bd infection.

20 induction and activation of Tregs during FV infection.

21 of PD-1 and TIGIT, within the first year of infection.

22 f seropositivity in patients with early Lyme infection.

23 animals euthanized on or before 15 days post infection.

24 tion on 94 patients with IEI with SARS-CoV-2 infection.

25 s, and CD11c(+) cells are susceptible to IAV infection.

26 ortant function of this protein in bacterial infection.

27 crophage activation in response to bacterial infection.

28 lowering bacterial load in a mouse model of infection.

29 ) T cells of patients at all stages of HIV-1 infection.

30 ing of the immune response induced after IDV infection.

31 transduced mammalian cells upon DENV-2/ZIKV infection.

32 her antibiotic use and rates of C. difficile infection.

33 uence GAS pathophysiology during soft tissue infection.

34 ited monocytes and other cells that controls infection.

35 ion occurring during the early stages of HIV infection.

36 approved therapies to treat or prevent CHIKV infection.

37 ulation size of infection N(e) for influenza infection.

38 nses in children and adults after SARS-CoV-2 infection.

39 ell or taste loss are indicative of COVID-19 infection.

40 their molecular drivers, and apply it to HIV infection.

41 fter virus entry and promote early stages of infection.

42 eed for early diagnosis and treatment of HIV infection.

43 for the innate immune response to S. aureus infection.

44 role in the survival of N2a cells upon prion infection.

45 nflammation preserve tissue integrity during infection.

46 spread locally to neighboring tissues during infection.

47 lity to and the natural course of SARS-CoV-2 infection.

48 of resistance lies in the entry step of MNV infection.

49 unds that act specifically to prevent fungal infection.

50 17-producing ILCS was not altered during SIV infection.

51 Serum IL-27 levels continued to rise during infection.

52 igate MuPyV-encephalopathy and control viral infection.

53 d AP-1/DNA-binding in response to S. mansoni infection.

54 ial treatment option for managing human SUDV infection.

55 h an intracellular destination that supports infection.

56 to a near depletion of KIF1A protein late in infection.

57 o global inhibition of mRNA translation upon infection.

58 ts had laboratory confirmation of SARS-CoV-2 infection.

59 rospective cohort demonstrated predictors of infection.

60 vel approaches for controlling P. aeruginosa infections.

61 ost effective way to prevent influenza virus infections.

62 gion policies have had on the growth rate of infections.

63 diagnostic test for asymptomatic low-density infections.

64 lular traps in helminth damage after primary infections.

65 fic hair shaft defects, atopy, and recurrent infections.

66 es and increases susceptibility to bacterial infections.

67 rtant for immune responses against microbial infections.

68 per-resistant to both bacterial and nematode infections.

69 pulmonary infections, including Aspergillus infections.

70 in 2018 for treating influenza A and B virus infections.

71 paid to submicroscopic Plasmodium falciparum infections.

72 patients in the adalimumab group had serious infections.

73 mbophilia; malignancy; critical illness; and infections.

74 ment strategy for children without recurrent infections.

75 per 100 000 persons for skin and soft tissue infections.

76 ions, whereas VVS/FCU missed 41 NG and 58 CT infections.

77 discrimination as a PBS >=4 in nonbacteremia infections.

78 ng antiretroviral therapy (ART) during acute infection, 2% of proviruses that persist on ART are gene

79 1) any further surgical procedure related to infection; (2) PJI-related death; or (3) use of long-ter

80 HIV infection (24.4%, 74/303) was not associated with other

81 identify symptoms (28.3%) or ways to prevent infection (30.2%).

82 Among participants with HIV infection, 36/108 (33%) had incidental findings compared

83 omes included: viral upper respiratory tract infection (47%), pharyngitis (18%), and allergy or asthm

84 ivir in a rhesus macaque model of SARS-CoV-2 infection(9).

85 iple brain regions through acute and chronic infection (90 days postinfection [dpi]) and quantified v

86 However, cases of Junin virus infection, a related virus, can be treated with convales

87 and acute bacterial skin and skin structure infection (ABSSSI) do not address treatment duration for

88 The CEACOV model tracks infections accrued by students and faculty, accounting f

89 is a major cause of acute lower respiratory infection (ALRI) in young children aged <5 years.

90 s of these case's households found prevalent infection among 57%, excluding first-reported cases 38%.

91 HPV33 and HPV51 tended to be involved in co-infection among both unvaccinated and vaccinated girls.

92 reaction (RT-PCR) are being used to rule out infection among high-risk persons, such as exposed inpat

93 the clinical characteristics and severity of infection among the individual PIV serotypes and between

94 We found substantial evidence of secondary infections among household contacts.

95 ak of new human immunodeficiency virus (HIV) infections among persons who inject drugs (PWID).

96 CMV-infection and -disease were successfully managed with le

97 ndrome (ARDS) secondary to influenza A(H1N1) infection and 10 age-matched, uninfected control lungs.

98 ssumed CMV vaccination would prevent primary infection and 2 models also assumed prevention of reinfe

99 -specific imprinting, which is essential for infection and autoimmunity.

100 This study investigated the effects of M.tb infection and BCG vaccination on B cell responses to het

101 ith PS to promote PS receptor-mediated virus infection and clearance of apoptotic cells.

102 ll-characterized iSLK.219 cell model of KSHV infection and established a new infection model of prima

103 der microglial cells susceptible to reovirus infection and expands current understanding of the recep

104 ent a novel therapeutic target against HIV-1 infection and HIV-associated neurological complications.

105 cess and exposure risk may be driving higher infection and mortality rates.

106 these data identify a role for TLR2 in DENV infection and provide insights into the complex interact

107 rategies that may shed light on this complex infection and provide insights into the future of microb

108 tions of patients with findings of pulmonary infection and those requiring further inpatient treatmen

109 es protective cellular response to microbial infection and tissue damage, but its aberrant activation

110 Thus, ferrets represent an infection and transmission animal model of COVID-19 that

111 t Escherichia coli strain, whereas recurrent infections and asymptomatic bacteriuria commonly result

112 omoting their ability to establish long-term infections and disease.

113 testing (RDT) for the improved detection of infections and for hotspots (RACD events yielding >=1 ad

114 nia and neutrophil dysfunction cause serious infections and inflammatory bowel disease in glycogen st

115 Bloodstream infections and invasive nontyphoidal Salmonellosis in pa

116 critical for limiting healthcare-associated infections and providing the best treatment for infected

117 impaired recruitment to localized bacterial infections and reduced survival that is, at least in par

118 Natural infections and vaccination with a pathogen typically sti

119 ostic imaging of obesity/diabetes, bacterial infection, and cancer.

120 skin in steady-state, psoriasis, dermatitis, infection, and malignant skin diseases.

121 proximately half the animals five weeks post-infection, and morphine/saline administration continued

122 led 323 women, of whom 234 had perinatal HIV infection, and reported age at sexual debut and history

123 -II-like cells) are permissive to SARS-CoV-2 infection, and showed robust induction of chemokines fol

124 ion (aOR, 2.2; 95% CI, 1.3-3.9), hepatitis C infection (aOR, 1.9; 95% CI, 1.1-3.4), black race (aOR,

125 estinal homeostasis.IMPORTANCE Enteric viral infections are a major cause of gastroenteritis worldwid

126 Post-KT infections are common and substantially impact mortality

127 te febrile illness, 5-20% progress to severe infection associated with significant morbidity and mort

128 BSSSI) do not address treatment duration for infections associated with bacteremia.

129 ble to potently inhibit authentic SARS-CoV-2 infection at a concentration as low as 0.007 micrograms

130 vices for timely identification of bacterial infections at the point-of-care and their usefulness in

131 Early diagnosis of an infection based on antibody detection might lead to less

132 Legionella pneumophila infection blocked xenophagic targeting of L. monocytogen

133 studies have been published and the true PeV infection burden is unknown.

134 nly in foamy macrophages in the lungs during infection but also accumulate in polymorphonuclear (PMN)

135 The pathogenic state investigated is infection by a human herpesvirus.

136 To identify host factors required for infection by SARS-CoV-2 and seasonal coronaviruses, we d

137 that this activity is required for efficient infection by SBV.

138 Viral infection can cause organ dysfunction, but its role in p

139 derlying susceptibility of host cells to MNV infection can lead to insights on the roles that specifi

140 Infection challenge with the common coccidian parasites

141 However, infection clearance does not happen once infection is es

142 cipants of the Copenhagen Comorbidity in HIV Infection (COCOMO) study.

143 he possible association between Blastocystis infection, colonic hypersensitivity (CHS), behavioral di

144 significantly elevated risk of M. genitalium infection compared to that for asymptomatic individuals

145 inked with the first few years of a national infection control campaign, but rates have since been st

146 provide a means of deriving new insights and infection control strategies based on the dynamics of th

147 essive drugs and antimicrobial approaches to infection control.

148 es in patients with diabetes might aggravate infection course.

149 Pre-existing Mtb infection creates an immunological environment that refl

150 roup A Streptococcus necrotizing soft tissue infections demonstrated a negative correlation between I

151 -/-) mice are highly susceptible to S aureus infections, demonstrating the relevance of CD163 for ant

152 History of infection during first year of life was not associated w

153 L-27 predispose neonatal mice to more severe infection during Gram-negative sepsis.

154 no more than one period at high risk of HIV infection during the follow-up period when not taking Pr

155 s can provide considerable advance notice of infection dynamics.

156 may manifest themselves in susceptibility to infection, early pathogenesis, innate viral control, ada

157 treat the acute lung injury after SARS-CoV-2 infection, especially for those with the ACE genotype as

158 genes, 2) defective leukocyte recruitment to infection foci, and 3) production of anti-inflammatory e

159 d reliably and rapidly distinguish bacterial infection from other, noninfectious causes of systemic i

160 lated with NV Lot 001-09NV and monitored for infection, gastroenteritis symptoms, and immune response

161 Relative control of HIV-1 infection has been linked to genetic and immune host fac

162 adult patients treated within 3 months after infection), HIV-1 diagnosis was not obtained in at least

163 racterized, immune-inducible gene Induced by Infection (IBIN) was diminished in osa knockdown flies.

164 Data on invasive mold infections (IMIs) after chimeric antigen receptor-modifi

165 hat lon-1 was highly expressed during animal infection, implying an important function of this protei

166 tum detection mean, being able to detect the infection in a latent phase, for the first time, in oliv

167 ted the role of the Kunjin virus helicase on infection in cell culture and in vivo This work provides

168 virus retinitis is an uncommon opportunistic infection in kidney transplant recipients.

169 MHV infection in mice provides an efficient cause-effect exp

170 to prevent or treat lethal viral respiratory infection in mice, with increased maturation of dendriti

171 on reducing immunity, reducing the burden of infection in mosquitoes, is a well-acknowledged but poor

172 Respiratory syncytial virus (RSV) infection in mouse and human lung is associated with oxi

173 gn of canonical vaccines aimed at disrupting infection in the host.

174 the most widely distributed tick-borne viral infection in the world.

175 ntry into host cells, but their relevance to infection in vivo is undefined.

176 s of IE in 92 PWID and 112 episodes of other infections in 107 PWID in whom IE was suspected but reje

177 is associated with the majority of zoonotic infections in 2018.

178 xacin (CIP) is extensively employed to treat infections in animal and human medicine.

179 n undetermined intermediate host, leading to infections in humans and other mammals.

180 es that have the potential to cause zoonotic infections in humans.

181 d in treating multi-drug resistant bacterial infections in humans.

182 Respiratory infections in the postacute phase of traumatic brain inj

183 s develop progressively in MAIT cells during infection, in parallel with TCR repertoire alterations.

184 lso involved in resistance to some bacterial infections, in anticancer immunity, and in anticancer th

185 the prevention of severe disease after virus infection include both a paucity of protective vaccines

186 regression analysis, risk factors for severe infection included pre-existing renal disease (odds rati

187 wide, with higher risks to develop pulmonary infections, including Aspergillus infections.

188 piratory syndrome-coronavirus-2 (SARS-CoV-2) infection increase the risk for acute nonischemic myocar

189 At the peak of C. rodentium infection, increased arginine concentration in the colon

190 te to maternal factors and early respiratory infections independent of atopy.

191 gamma stimulation and murine norovirus (MNV) infection induce GBP2 expression in murine macrophages.

192 Dengue infection induces a spectrum of clinical symptoms, rangi

193 that persistent Helicobacter pylori gastric infection influences immune responses to oral enteric va

194 Besides viral infections, IRF3 is also involved in resistance to some

195 Chronic HBV infection is a major cause of liver disease and cancer w

196 Campylobacter infection is common in this cohort and associated with c

197 er, infection clearance does not happen once infection is established, and this may be because of the

198 which remain first-line antibiotics for many infections, is an important part of efforts to address a

199 its of lung function improvement in SARS-CoV infections, it has been hypothesized that the benefits o

200 Chronic cytomegalovirus (CMV) infection leads to long-term maintenance of extraordinar

201 Infection led to a 3-fold depletion of ILC3 in the colon

202 unity to establish and maintain a persistent infection may lead to the development of new therapeutic

203 erebrovascular disease in patients with dual infection merits further investigation.

204 Employing a quasivirus infection model and selection for G418 resistant genomes

205 odel of KSHV infection and established a new infection model of primary lymphatic endothelial cells (

206 dated the results in a murine Leishmania ear infection model.

207 in biosynthesis inhibitors in standard mouse infection models.

208 , estimating an effective population size of infection N(e) for influenza infection.

209 and in heathy control subjects with neither infection (n = 10).

210 Here, we found that when phage infections occur on solid media, a high proportion of th

211 Large decreases in ICU-acquired infections occurred across the UK ICU network linked wit

212 We demonstrate that lytic MHV68 infection of B cells, macrophages, and fibroblasts leads

213 inolytic protease, as important for parasite infection of host macrophages and a potential therapeuti

214 Infection of HPCs with an HCMVDeltamiR-US5-2 mutant resu

215 avian and animal hosts for commensalism and infection of humans for diarrheal disease.

216 Interestingly, PRV infection of neuronal cells leads not only to a nonspeci

217 eity in pathogen prevalence and intensity of infection of the chytrid fungus Batrachochytrium dendrob

218 yngeal candidiasis (OPC) is an opportunistic infection of the oral mucosa caused by the commensal fun

219 hiPSCs and showed that productive SARS-CoV-2 infection of these organoids is associated with increase

220 was threshold-based, which led to the fewest infections of all strategies tested (9,900; [IQR: 8,720-

221 in animals alongside successful experimental infections of pets, such as cats, ferrets and dogs, rais

222 family of viruses that can cause respiratory infections of varying severity.

223 In our population, the effect of Adv36 infection on lipid profile varied between healthy indivi

224 We evaluated the impact of maternal HIV infection on the burden of RSV among mothers and their i

225 s also necessary for an effective control of infections on the other hand.

226 [ABCs]) is increased in mice and humans with infections or autoimmune diseases.

227 EBV/KSHV co-infection (OR = 5.71(1.58-7.12)), HIV positivity (OR = 2

228 tomatic controls with presence of rhinovirus infection (OR:4.23; 95%CI 1.16-14.22, p<0.05).

229 ace of stressors as different as starvation, infection, or protein misfolding.

230 hat complement function modulates SARS-CoV-2 infection outcome, the data point to putative transcript

231 Upon infection, paramyxoviruses cause a second type of membra

232 ty T cell clones declined during the chronic infection phase, likely due to cellular senescence.

233 ical importance, little is known about their infection phenotypes.

234 iego investigated an outbreak of hepatitis A infections primarily among people experiencing homelessn

235 to promote vector exposure neither predicted infection probability nor parasite diversity.

236 usion, this robust cell culture model of HEV infection provides a powerful tool for studying viral-ho

237 eases including human immunodeficiency virus infection, psoriasis, rheumatoid arthritis, and systemic

238 Rapid Diagnostics in Categorizing Acute Lung Infections (RADICAL) study.

239 mortality) of 1.5, 2.0, and 3.0 at differing infection rate scenarios, including full suppression (0.

240 pite these interventions, confirmed COVID-19 infection rates have been high in the United Kingdom.

241 ially constrains Leucocytozoon diversity and infection rates, landscape features, such as vegetation

242 With sharply rising infection rates, patient groups characterized by an enha

243 ta here suggest a critical infusion time for infection reduction (24.6 min before incision).

244 vestigated the long-term prognosis following infection-related hospitalization.

245 Current mouse models of CCHFV infection reliably succumb to virus challenge but vary i

246 plant immunity against hemibiotrophic fungal infection remains poorly understood.

247 order (OUD) who are hospitalized for serious infections requiring prolonged intravenous antibiotics m

248 tion of many ISGs, which confers broad viral infection resistance.

249 %) lower susceptibility to influenza A(H3N2) infection, respectively.

250 n ivermectin against hepatic and blood stage infections, respectively.

251 .), although both wild-type and DUBmut virus infections resulted in similar liver pathology.

252 ldren with unexplained recurrent respiratory infections, revealing age-dependent variation and sugges

253 , monitoring, and reduction of any potential infection risk associated with FcRn inhibition, in addit

254 patient groups characterized by an enhanced infection risk will be challenged by the virus.

255 We find that most SARS-CoV-2 infections sampled during this time derive from a single

256 induction of these elements following MHV68 infection should provide insight into core elements of S

257 mbda airway secretion; (b) subjects with RSV infection showed the highest IFN-lambda airway levels; a

258 induction of chemokines following SARS-CoV-2 infection, similar to what is seen in patients with COVI

259 their co-existence in hostile polymicrobial infection sites.

260 immune mechanisms underpinning the parasitic infections, some of which are parasite-specific, opens u

261 immunological environment that reflects Mtb infection status and influences the susceptibility of CD

262 Demographic data, TBM severity grade, HIV co-infection status, and clinical endpoints by 3 months wer

263 6J CD300LF made the cells permissible to MNV infection, suggesting that the cause of resistance lies

264 lls derived from individuals with latent Mtb infection supported more efficient HIV-1 transcription,

265 were: P: age, gender and ACLF type; I: drug, infection, surgery, and variceal bleeding; R: systemic i

266 oids as a platform to investigate SARS-CoV-2 infection susceptibility of brain cells, mechanisms of v

267 females had a lower incidence of SARS-CoV-2 infection than adolescents or adults and males.

268 fected [HEU]) are more susceptible to severe infection than HIV-unexposed, uninfected (HUU) children,

269 vivo enables selective ISG expression during infection that confers antiviral protection but minimize

270 Hepatitis A virus (HAV) is a common infection that is transmitted through the fecal-oral rou

271 an altered Th2 immune response following RSV infection that leads to more severe immunopathology.

272 ract infections (UTIs) are common, recurrent infections that can be mild to life-threatening.

273 o accomplish the remarkable task of lifelong infection, the Epstein-Barr virus (EBV) switches between

274 s cumulative and aberrant as, after multiple infections, the epithelium was markedly thickened and bl

275 man cytomegalovirus (HCMV) causes a lifelong infection through establishment of latency.

276 effective device, comprehensibly mitigating infection transmission globally.

277 recovery and variable cell susceptibility to infection), using our software modules and publicly-avai

278 uidelines for pneumonia (PNA), urinary tract infection (UTI), and acute bacterial skin and skin struc

279 Urinary tract infections (UTIs) are common, recurrent infections that

280 this miRNA specifically inhibits Salmonella infection via modulation of endolysosomal trafficking an

281 Severe COVID-19 infection was noted in 74 (37.6%) patients, requiring in

282 ced by numerous influenza virus vaccines and infections, we found mAbs targeting conserved neutralizi

283 2 to the molecular pathogenesis of T. gondii infection were examined in vitro and in vivo.

284 Independent predictors of infection were injection drug use as a risk factor for H

285 Pooled specimens missed 2 NG and 11 CT infections, whereas VVS/FCU missed 41 NG and 58 CT infec

286 s was also detected following C. trachomatis infection, which was reversed by blocking LOS synthesis.

287 rotype ayw)-either from a transgene or after infection with an adeno-associated virus that transferre

288 inically silent in this patient until lethal infection with CMV.

289 s a broad capacity to neutralize and prevent infection with contemporary H3N2 strains.

290 s indicated a graded increase in the risk of infection with higher levels of FGF23 (HR, 1.51; 95% CI,

291 Infection with laboratory-adapted Mtb H37Rv resulted in

292 ers in the spleen were observed during acute infection with myeloid-restricted ZIKV that precluded th

293 NV-32, protected ferrets in lethal models of infection with NiV Bangladesh 3 days after exposure.

294 hypothesized that elevated stool toxins and infection with ribotype 027 associate with severe diseas

295 Although the diagnosis of infection with SARS-CoV-2 is microbiological, imaging te

296 A key unanswered question is whether infection with SARS-CoV-2 results in protective immunity

297 al contact carries some risk for exposure to infection with severe acute respiratory syndrome coronav

298 les exhibited spontaneous neonatal bacterial infections with robust mucoinflammatory features, includ

299 en to express foreign virulence genes during infection without the need to evolve binding sites for a

300 ya, are responsible for more than 50 million infections worldwide every year, with an overall increas