ライフサイエンスコーパス: infectious agent

1 wing the toxins to move cell-to-cell like an infectious agent.

2 e community in preventing the spread of that infectious agent.

3 ongenital infection but in the absence of an infectious agent.

4 nal fluid (CSF) was performed to identify an infectious agent.

5 tailored and robust manner, inclusive of the infectious agent.

6 lls more individuals per year than any other infectious agent.

7 e misfolded proteins ("prions") are also the infectious agent.

8 Torque Teno virus (TTV) is a ubiquitous infectious agent.

9 ells expressing antibodies that can bind the infectious agent.

10 ins from blood without first identifying the infectious agent.

11 cause of mortality worldwide due to a single infectious agent.

12 nced the transmission characteristics of the infectious agent.

13 e similar, but not identical to the original infectious agent.

14 behavior differed markedly from that of the infectious agent.

15 s via multiple mechanisms depending upon the infectious agent.

16 or example, in innate immune cells facing an infectious agent.

17 ing worldwide cause of death due to a single infectious agent.

18 quent cause of death in humans from a single infectious agent.

19 tive agent of TB, is categorized as a highly infectious agent.

20 ed more people in 2017 than any other single infectious agent.

21 ed forecasting systems treat ILI as a single infectious agent.

22 therapeutics and vaccines for this emerging infectious agent.

23 analysis allows simple identification of the infectious agent.

24 tted through fomites: objects able to convey infectious agents.

25 nate might result in an impaired response to infectious agents.

26 esistance to the environment and immunity to infectious agents.

27 ation network is a common target for diverse infectious agents.

28 diate measurements for the identification of infectious agents.

29 cells and drives the pathogenesis of various infectious agents.

30 medicinal chemistry of these closely related infectious agents.

31 it direct contact between the epithelium and infectious agents.

32 imation, and biocrimes involving tracking of infectious agents.

33 against Mycobacterium tuberculosis and other infectious agents.

34 to hosts and can spread antigens as well as infectious agents.

35 responses to contain and limit the spread of infectious agents.

36 of genetic diseases and for the detection of infectious agents.

37 c, cytoplasmic, aggregate-prone proteins and infectious agents.

38 tivity needed for front-line defense against infectious agents.

39 n a manner distinct from rapidly replicating infectious agents.

40 cell type to control and eradicate specific infectious agents.

41 velopment of vaccination protocols for other infectious agents.

42 t responses against Y. pestis and many other infectious agents.

43 inhibitor of PCs to prevent PC activation of infectious agents.

44 also provide enhanced defense against other infectious agents.

45 disease when challenged with inflammatory or infectious agents.

46 or of intestinal epithelial defenses against infectious agents.

47 ave the potential to combat a broad range of infectious agents.

48 g the characteristics of immune responses to infectious agents.

49 genetic associations in the context of these infectious agents.

50 15% of all cancer cases are attributable to infectious agents.

51 it immune responses to occur against foreign infectious agents.

52 s of countermeasures against these dangerous infectious agents.

53 d asthma; whereas allergens can partly mimic infectious agents.

54 accines that induce protection against other infectious agents.

55 , represent a major frontier in the study of infectious agents.

56 use not only for cancer therapy but also for infectious agents.

57 in measuring response to other vaccines and infectious agents.

58 ) is a leading cause of birth defects due to infectious agents.

59 strategy by which mammalian hosts respond to infectious agents.

60 platform applicable across a broad range of infectious agents.

61 ide novel avenues for drug targeting against infectious agents.

62 of defense against exposure of the airway to infectious agents.

63 d water supply, environmental toxicants, and infectious agents.

64 ic processes often govern host contacts with infectious agents.

65 estimate time and extent of spread of these infectious agents.

66 al role in protecting the lungs from inhaled infectious agents.

67 s on mucosal immunity for protection against infectious agents.

68 e of skin cancer and the response to several infectious agents.

69 t in unconventional ways to remain viable as infectious agents.

70 suboptimal antibody responses against common infectious agents.

71 tance, both directly and indirectly, against infectious agents.

72 Vs) are the most common sexually transmitted infectious agents.

73 ich in the case of some pathogens act as the infectious agents.

74 l outbreaks is desirable to characterize the infectious agent and determine its evolutionary rate.

75 Many cases of mastitis involve no known infectious agent and may fundamentally be due to autoimm

76 with a focus on F. nucleatum as a mutualist, infectious agent and oncogenic microorganism.

77 er pylori is the single leading carcinogenic infectious agent and the main cause of stomach cancer.

78 o the study of the unorthodox nature of this infectious agent and the molecular mechanism by which th

79 eculated to trigger the syndrome, a specific infectious agent and underlying pathophysiological mecha

80 to various contaminations including toxins, infectious agents and chemical contaminants.

81 ar the body of undesirable particles such as infectious agents and debris.

82 proach for the diagnosis of genetic defects, infectious agents and diseases.

83 (CHIMs) have become available for a range of infectious agents and have proved invaluable for underst

84 low-titer antibodies for detection of other infectious agents and host proteins.

85 n orchestrating innate responses to distinct infectious agents and in maintaining inflammatory respon

86 oop contributes to pathological responses to infectious agents and is therefore tightly regulated.

87 vaccines have been developed by cultivating infectious agents and isolating the inactivated whole pa

88 initial lymph node metastases, as well as by infectious agents and parasites.

89 Tests for infectious agents and pesticides were negative.

90 entify commonality in non-human sequences by infectious agents and putative contamination events, we

91 acteristics, including their ability to bind infectious agents and secrete many immunomodulatory cyto

92 The periodic emergence of new infectious agents and the genetic and antigenic evolutio

93 er, identifying associations between defined infectious agents and the initiation of chronic disease

94 f conserved microbial structures to identify infectious agents and the use of supramolecular organizi

95 can substantially impact immune responses to infectious agents and their products.

96 pport annotation of disease processes due to infectious agents and to mutation.

97 ular organisms are exposed to a diversity of infectious agents and to the emergence and proliferation

98 c cells in these models to impact control of infectious agents and tumor growth.

99 tors are being developed as vaccines against infectious agents and tumour-associated antigens, becaus

100 likely relevant for other viruses (and other infectious agents) and for remote signaling of other pro

101 s the world's leading cause of death from an infectious agent, and is a serious health problem in Pap

102 ferentiation in accord with the nature of an infectious agent, and the contingency of differentiation

103 li, including toxins, venoms, allergens, and infectious agents, and play critical roles in resistance

104 icroglia are crucial for the phagocytosis of infectious agents, apoptotic cells and synapses.

105 y that the host immune reactions against the infectious agent are very decisive for acuteness and dur

106 Infectious agents are often considered potential trigger

107 the diversity and geographic distribution of infectious agents are only starting to be investigated.

108 e standard diagnostic approach when specific infectious agents are sought in a clinic specimen.

109 Infectious agents are the third highest human cancer ris

110 Ubiquitin E3 ligases encoded by infectious agents are well known, as are a variety of vi

111 decreased exposure at a young age to certain infectious agents as a result of improved hygiene, incre

112 ble to fully understand all aspects of these infectious agents as well as for surveillance of viral p

113 ophylactic vaccines that provoke immunity to infectious agents, as in allergy the patient is presensi

114 In an attempt to explore infectious agents associated with nasopharyngeal carcino

115 Case incidence and infectious agent association.

116 Ample evidence exists for the presence of infectious agents at the maternal-fetal interface, often

117 they can be used to measure connectivity of infectious agents between sites, test hypotheses regardi

118 Most FDA-approved adjuvants for infectious agents boost humoral but not cellular immunit

119 ms such as myalgias and fever, suggesting an infectious agent, but the majority have no identifiable

120 ve drugs as mycophenolic acid (MPA) and anti-infectious agents, but some PTN remain unexplained.

121 y a critical role in immune defenses against infectious agents, but there have been no reports about

122 atory response results in the elimination of infectious agents by neutrophils and monocytes, followed

123 Creutzfeldt-Jakob disease agent and that the infectious agent can be present in the spleen without CN

124 is (Mtb) and provided original proof that an infectious agent can cause human disease.

125 osis and antibiotics targeting this emerging infectious agent can eradicate the infection and prevent

126 hic models coupled with biological models of infectious agents can characterize dispersal networks of

127 Such transmission of infectious agents can occur within the hospital, clinic,

128 e with humans, cross-species transmission of infectious agents can occur.

129 Viruses and other infectious agents cause more than 15% of human cancer ca

130 lesser extent, the airborne transmission of infectious agents caused by the misuse of respiratory pr

131 Staphylococcus aureus is the most common infectious agent causing pyogenic spondylodiscitis.

132 The distributions of most infectious agents causing disease in humans are poorly r

133 ophagous flies could be used to identify the infectious agents circulating in wild vertebrates.

134 Established infectious agents continue to be a major cause of human

135 a variety of laboratory methods to identify infectious agents contributing to deaths of children <5

136 eterioration remains elusive and no specific infectious agents could be discerned.

137 The infectious agents covered in this assessment include ade

138 Prevention strategies against infectious agents demand rapid and accurate detection an

139 h the potential to recognize the universe of infectious agents depends on proper regulation of TCR si

140 Infectious agents develop intricate mechanisms to intera

141 he use of metagenomics for identification of infectious agents directly from patient samples, to aid

142 ss able to resist and/or eliminate secondary infectious agents due the effect of PRRSV on the thymus,

143 source of prions long before exposure to the infectious agent during and after the birthing process o

144 Infectious agents, especially bacteria and their compone

145 immunity may be a general mechanism by which infectious agents exacerbate symptoms associated with ot

146 ic antibodies that can be protective against infectious agents exhibiting the same carbohydrate modif

147 elicobacter pylori is one of the most common infectious agents found in the human stomach.

148 diverse of these receptors as it recognises infectious agents from a range of pathogenic groups.

149 d to enhanced between-group contact after an infectious agent has been introduced.

150 nal definition, the designation of prions as infectious agents has become problematic.

151 In mammals, chronic diseases resulting from infectious agents have been associated with functional T

152 Infectious agents have been identified as a major cause

153 , in which cancer cells themselves act as an infectious agent, have been identified in Tasmanian devi

154 approach, which should be applicable to many infectious agents, holds promise for the construction of

155 ered which have the potential to act as anti-infectious agents; however, the proteins are toxic and n

156 Arthropods transmit diverse infectious agents; however, the ways microbes influence

157 tract represents a portal of entry for many infectious agents; however, to date specific strategies

158 ants that would be most likely to encounter infectious agents (i.e. foragers) using integrated socia

159 s secreted at increased rates in response to infectious agents, implying that mucins exert a protecti

160 id diagnostics that enable identification of infectious agents improve patient outcomes, antimicrobia

161 mic influenza virus was the most devastating infectious agent in human history, causing fatal pneumon

162 egative staphylococci are a highly prominent infectious agent in peritonitis, and suggest caution aga

163 (HK) is the leading cause of blindness by an infectious agent in the developed world.

164 blood profiling using RNASeq to discriminate infectious agents in adults with microbiologically defin

165 GS simultaneously assays for a wide range of infectious agents in an unbiased manner, it can identify

166 hypothesis proposes that reduced exposure to infectious agents in early life would explain the increa

167 gens that are among the eight most prevalent infectious agents in hospitals.

168 olecular characterization of known and novel infectious agents in human disease.

169 Their emergence as infectious agents in humans coincided with changes in th

170 eroviruses (EVs) are among the most frequent infectious agents in humans worldwide and represent the

171 management of persistent diarrhea caused by infectious agents in immunocompetent individuals worldwi

172 nfections and an efficient approach to study infectious agents in large cohorts.

173 m mounts a response against RSV and specific infectious agents in nasal microbiota.

174 onsidered, it is important to test for other infectious agents in parallel, as cross-reactivity can o

175 as a chronic inflammatory disease caused by infectious agents in RA seems biologically plausible.

176 ICV) as part of its routine surveillance for infectious agents in specimens collected from patients p

177 literature that supports the involvement of infectious agents in the aetiology of type 1 diabetes in

178 The idea that infectious agents in the brain have a role in the pathog

179 Prions are the infectious agents in the class of fatal neurodegenerativ

180 e been established as ecologically important infectious agents in the oceans; however, viral infectio

181 Interest is growing in the role of infectious agents in the pathogenesis of dementia, but c

182 he understanding of the contribution of some infectious agents in the progression of cancers.

183 can result in productive replication of the infectious agents in the recipient cell.

184 Our PCR assays detected DNAs of various infectious agents in tumor specimens, especially HHV6, H

185 ethods for early detection and monitoring of infectious agents in wildlife.

186 osure to infection and the properties of the infectious agent, in addition to the genetic susceptibil

187 They also face pressure from infectious agents, including elephant endotheliotropic h

188 so needs to understand broader categories of infectious agents, including pathogenic amoebae and fung

189 ic cell receptor DC-SIGN by numerous chronic infectious agents, including Porphyromonas gingivalis, i

190 ude habitat degradation, climate change, and infectious agents, including viruses.

191 Attenuated acute infectious agents induce strong CD8(+) T cell immunity,

192 sed on a stochastic model of a population of infectious agents inside one host cell, extending the bi

193 Immunity to infectious agents involves a coordinated response of inn

194 Additionally, timely detection of infectious agents is critical in early diagnosis and tre

195 Timely detection of infectious agents is critical in early diagnosis and tre

196 tion of high-affinity Abs in response to Ags/infectious agents is essential for developing long-lasti

197 oRNAs, but their role in the transmission of infectious agents is less established.

198 erstanding the genetics of susceptibility to infectious agents is of great importance to our ability

199 CD8(+) T cells are essential for eliminating infectious agents, it is crucial to understand why they

200 y being a first layer in our defense against infectious agents, it is essential for our ability to de

201 The protein-only infectious agents known as prions exist within cellular

202 he influenza virus is one of the most deadly infectious agents known to man and has been responsible

203 ancisella tularensis (Ft) is one of the most infectious agents known.

204 The discovery of the first non-cellular infectious agent, later determined to be tobacco mosaic

205 (IFN) is an early host response to different infectious agents leading to the induction of hundreds o

206 immune response, triggered in most cases by infectious agents, leads to severe hyperinflammation.

207 iologic, and pathologic evidence supports an infectious agent, likely entering through the lung.

208 cida, mouse cytomegalovirus and DNA, and the infectious agents Listeria monocytogenes and Aspergillus

209 epidemiologic data suggest that exposure to infectious agents may be associated with increased MS ri

210 hypothesis suggests that higher exposure to infectious agents may be one reason for regional differe

211 and exposure to the external world, in which infectious agents may play a role.

212 lation or activation of oncogenes from these infectious agents might be involved in the pathogenesis

213 s should be 'non-self antigens' accompanying infectious agents, might disrupt control of the adaptive

214 he prototypical vaccinia virus, the emerging infectious agent monkeypox virus, and the potential biot

215 Infectious agents must be quickly and efficiently contro

216 the leading cause of mortality from a single infectious agent, Mycobacterium tuberculosis Relevant im

217 The prevalence of these infectious agents necessitates rapid, point-of-care sens

218 the most effective prophylaxis against these infectious agents, no single vaccine simultaneously prov

219 is an emerging pathogen and is the causative infectious agent of Kaposi sarcoma and two malignancies

220 Prions, the infectious agent of scrapie, chronic wasting disease and

221 The infectious agent of the disease anthrax is the spore of

222 obacterium tuberculosis (Mtb), the causative infectious agent of tuberculosis (TB), kills more indivi

223 ected with Salmonella and Eimeria, two major infectious agents of gastrointestinal diseases of poultr

224 nteroviruses are among the most common viral infectious agents of humans and are primarily transmitte

225 atory reagent contaminants and not bona fide infectious agents of humans underscores the rigorous app

226 and 2 (HSV-1 and HSV-2) are the most common infectious agents of humans.

227 ines consist of nongenetic components of the infectious agent or disease-related epitope.

228 Despite the absence of infectious agents or an autoimmune trigger, induction of

229 ppressing local or systemic immunity against infectious agents or cancer.

230 stronaut's ability to prevent acquisition of infectious agents or reactivation of latent infection.

231 on sequencing data could be used to identify infectious agents or structural variants, but there has

232 e metabolic adaptation, mediate responses to infectious agents, orchestrate fibrosis in a yin-yang in

233 is minireview attempts to cover the scope of infectious agents potentially implicated in CSA, specime

234 The inactivation of infectious agents present in diagnostic samples is criti

235 ulating that misfolded protein seeds act as "infectious agents" propagating aggregation of nominally

236 ion for MHC molecules that effectively clear infectious agents provides an advantage to humans.

237 t-encoded prion protein (PrP), act as lethal infectious agents, PrP amyloid fibrils produced in vitro

238 is the leading cause of death from a single infectious agent, requiring at least 6 months of multidr

239 may have resulted from the yet undetermined infectious agent responsible for encephalitis lethargica

240 Prions are proteinaceous infectious agents responsible for the transmission of pr

241 Prions, the infectious agents responsible for transmissible spongifo

242 miological information with knowledge of the infectious agent(s).

243 These results suggest that exposure to infectious agents should be an important consideration i

244 m (e.g. from clinical samples with suspected infectious agents), shows promise for the rapid phylogen

245 test their safety by ensuring the absence of infectious agents; specifically prions, which are highly

246 Hence, depending on the infectious agent, strong recall of mCTLs during secondar

247 ) that are conserved across broad classes of infectious agents such as bacteria and viruses.

248 lso be useful to detect biomarkers for other infectious agents such as Ebola, HIV, and Zika.

249 of omic profiles measuring host response to infectious agents such as influenza viruses at multiple

250 in the cultivation and management of highly infectious agents, such as acid-fast bacilli and systemi

251 how our microbiome influences the impact of infectious agents, such as C. difficile; how our microbi

252 es the complications associated with certain infectious agents, such as pelvic inflammatory disease,

253 These findings reveal that systemic infectious agents, such as T. gondii, can induce long-te

254 Intriguingly, several infectious agents, such as Toxoplasma, Legionella, and C

255 This interaction might apply to other infectious agents, such as viruses, that elicit cognitiv

256 public health, as the deliberate release of infectious agents, such smallpox or a related virus, mon

257 s were submitted to the state laboratory for infectious agent testing.

258 Norovirus is a highly transmissible infectious agent that causes epidemic gastroenteritis in

259 ssed the special challenges in combatting an infectious agent that causes sporadic outbreaks in resou

260 Prion or PrP(Sc) is a proteinaceous infectious agent that consists of a misfolded and aggreg

261 e of hypermutable mechanisms have evolved in infectious agents that allow for rapid generation of gen

262 Prions are notorious protein-only infectious agents that cause invariably fatal brain dise

263 Prions are infectious agents that cause lethal brain diseases; they

264 Prions are infectious agents that cause neurodegenerative diseases

265 It is notable however that one of the main infectious agents that causes periodontal disease is an

266 Identification of the infectious agents that circulate within wild animal rese

267 Prions or PrP(Sc) are proteinaceous infectious agents that consist of misfolded, self-replic

268 Prions or PrP(Sc) are proteinaceous infectious agents that consist of misfolded, self-replic

269 limited in identification and implication of infectious agents that pose threats to human health and

270 tive-strand (+)RNA viruses are intracellular infectious agents that reorganize subcellular membranes

271 Prions are unique infectious agents that replicate without a genome and ca

272 on protein (PrP) were first characterized as infectious agents that transmit pathology between indivi

273 These results imply that for control of an infectious agent, the time between the distant exposure

274 ot be sufficient to understand the spread of infectious agents, their susceptibility to vaccine thera

275 In creating vaccines against infectious agents, there is often a desire to direct an

276 Prions are lethal infectious agents thought to consist of multi-chain form

277 ion of the route of transmission taken by an infectious agent through a host population is critical t

278 of intrauterine infection and the commonest infectious agent to affect allograft recipients, yet the

279 Some studies link exposure to infectious agents to development of brain disorders; oth

280 hways, but also may exert protection against infectious agents to facilitate recovery from acute infl

281 proteins are incorporated directly into the infectious agents, to investigate how proteins interact

282 xposure to air and traffic pollution, fungi, infectious agents, tobacco smoke, and other early-life a

283 of animal models to experimentally study how infectious agents transmit between hosts limits our unde

284 The cancer cell is the 'infectious' agent transmitted as an allograft by biting.

285 ted with the classic transfusion-transmitted infectious agents (TTIs; hepatitis B virus [HBV], HIV, h

286 rganisms are potential pathogens that can be infectious agents under some circumstances, and developm

287 Stool specimens were tested for 37 infectious agents using TaqMan Array technology.

288 mucosal sites is critical for the control of infectious agents using these routes to enter the body.

289 provide protective humoral immunity against infectious agents, vaccines that elicit potent CD8 T cel

290 Among the major infectious agents, viruses most frequently enter the bra

291 Phylogenetic analyses revealed that this infectious agent was affiliated with the Perkinsea: a pa

292 ry network driving host response to multiple infectious agents, we integrated host transcriptomes and

293 The most frequently identified infectious agents were respiratory viruses, accounting f

294 detection in the BALF by PCR, whereas other infectious agents were undetectable.

295 Prions are infectious agents which cause rapidly lethal neurodegene

296 e autophagy machinery controls the burden of infectious agents while simultaneously limiting inflamma

297 Satellite RNAs are the smallest infectious agents whose replication is thought to be com

298 standing the causal associations of specific infectious agents with certain B-cell lymphomas has allo

299 mmune response leads to rapid elimination of infectious agents, with seemingly little long-term impai

300 how that honeybee EIDs are indeed widespread infectious agents within the pollinator assemblage.