ライフサイエンスコーパス: infectious particle

1 leads to the production of spores (suspected infectious particles).

2 s the envelope proteins of HBV to produce an infectious particle.

3 tection of as little as one oligomeric PrPSc infectious particle.

4 eolytic cleavage of Gag results in a mature, infectious particle.

5 re form that differs from that of the mature infectious particle.

6 viruses (DENV) undergo maturation to become infectious particles.

7 tions in virus RNA synthesis and assembly of infectious particles.

8 us particles that are indistinguishable from infectious particles.

9 rane protein (prM), turning inert virus into infectious particles.

10 howed a fourfold reduction in the release of infectious particles.

11 e titers are not equivalent to the number of infectious particles.

12 s that sustain viral replication and produce infectious particles.

13 acellular plasma membrane domain to assemble infectious particles.

14 viral capsids and thus the formation of new infectious particles.

15 uman stool sample, and produced 10-fold-more infectious particles.

16 some biogenesis pathway for the formation of infectious particles.

17 consistent with the transmission of multiple infectious particles.

18 role for Cys87 and Cys207 in the assembly of infectious particles.

19 NA quantitative detection and the release of infectious particles.

20 uction of human immunodeficiency virus (HIV) infectious particles.

21 in plaque size and a sustained production of infectious particles.

22 tag, which are efficiently incorporated into infectious particles.

23 ing in misleading estimates of the number of infectious particles.

24 ections and were analyzed for APV genome and infectious particles.

25 assembly of foreign structural proteins into infectious particles.

26 omic RNA requires full-length Gag to produce infectious particles.

27 and VP5 are exposed on the outer surface of infectious particles.

28 generated about 1800-times fewer background infectious particles.

29 99 permits assembly, but blocks formation of infectious particles.

30 atant and an impairment in the production of infectious particles.

31 HIV-1 particle maturation and generation of infectious particles.

32 ed into a near-spherical nanochamber to form infectious particles.

33 ey were present in a 1:1 ratio in the mature infectious particles.

34 in failed packaging and assembly of only non-infectious particles.

35 uced phage replication and the generation of infectious particles.

36 specifically inhibit HCV by interacting with infectious particles.

37 y secreted glycoproteins not associated with infectious particles.

38 hannel activity, and, ultimately, release of infectious particles.

39 tion of DENV-2 genomic RNA and production of infectious particles.

40 onents, resulting in the formation of mature infectious particles.

41 are responsible for the production of 95% of infectious particles.

42 global structural rearrangements to produce infectious particles.

43 ncapsidated into viral complexes to generate infectious particles.

44 on, viral DNA replication, and production of infectious particles.

45 heir efficient encapsidation into phage-like infectious particles.

46 impacted infections initiated by one or many infectious particles.

47 is the main component of these proteinaceous infectious particles.

48 E (ApoE) was sufficient to permit release of infectious particles.

49 fRNA to compete with gRNA for packaging into infectious particles.

50 oproteins were efficiently incorporated into infectious particles.

51 six of the MSD mutants were able to produce infectious particles.

52 ect assembly, budding, and maturation of new infectious particles.

53 nd +2L mutants were not capable of producing infectious particles.

54 must incorporate viral glycoproteins to form infectious particles.

55 filter and incubating the filter to release infectious particles.

56 ration of immature vaccinia virus virions to infectious particles.

57 proper virus assembly and for the budding of infectious particles.

58 rticle assembly near the ER but fail to form infectious particles.

59 eins to the formation of SaPI-specific small infectious particles.

60 cdE2 restored NC assembly but not release of infectious particles.

61 ls, HCV replicated persistently and released infectious particles.

62 ease (PR) is essential for the production of infectious particles.

63 nd plays a critical role in the formation of infectious particles.

64 a source case of tuberculosis (2) generates infectious particles (3) that survive in the air and (4)

65 p-regulated expression of viral proteins and infectious particles after infection with pathogenic age

66 found that mouse cytomegalovirus can produce infectious particles albeit at a level that does not sus

67 Infectious particles also contain high levels of this pr

68 for the assembly of viral components into an infectious particle and that budding is delayed in Mmut

69 , the majority of E2 was not associated with infectious particles and failed to sediment on sucrose g

70 some biogenesis pathways both for assembling infectious particles and for establishing host permissiv

71 was necessary for assembly of VSV RNAs into infectious particles and that this signal was supplied b

72 l component for secretion of Dengue and Zika infectious particles and their corresponding virus like

73 the +3L Env glycoprotein was able to produce infectious particles and was constitutively fusogenic.

74 ion of larger syncytia, higher production of infectious particles, and a more potent cytopathic effec

75 enic after intracranial infection with 10(5) infectious particles, and BNSP-Gag produced a 50%-reduce

76 ts proteolytic processing, the generation of infectious particles, and cell entry.

77 y inactivating both extra- and intracellular infectious particles, and it is nontoxic in vitro and in

78 expression, genome replication, assembly of infectious particles, and spread to other cells.

79 HV structural protein expression, release of infectious particles, and syncytium formation, and endog

80 acting element for the assembly of RNAs into infectious particles, and they delineate RNA sequences t

81 The E2 that was incorporated into infectious particles appeared as a triplet of diffuse ba

82 The RNA genomes in both immature and infectious particles are dimers, and interactions betwee

83 y, HCV RNA, and viral antigens suggests that infectious particles are likely to be present in the lar

84 n ER signal sequence, spikes do not form and infectious particles are not assembled, suggesting an ad

85 In this report, we demonstrate that infectious particles are present both within the infecte

86 n packaged in the released virions, but some infectious particles are still released, presumably as R

87 vered nematode viruses are incorporated into infectious particles as protruding fibers covalently lin

88 gly, "prion" was defined as a "proteinaceous infectious particle." As the concept has expanded to inc

89 nes to acquire the outer capsid proteins for infectious particle assembly.

90 tein, plays a critical, but unknown, role in infectious particle assembly.

91 hich in turn promote HCV RNA replication and infectious-particle assembly, respectively.

92 S2 to fine tune both HCV RNA replication and infectious-particle assembly.IMPORTANCE Chronic infectio

93 also identified the precise sequence of the infectious particle-associated ORF2 capsid protein.

94 a noninteracting, passive scalar-a proxy for infectious particles-being advected and diffused by turb

95 nal 29 nucleotides of Tr allowed assembly of infectious particles but that the 5' terminal 22 nucleot

96 ved ORF2) forms that are not associated with infectious particles, but are the major antigens in HEV-

97 a subclinical phase with constant levels of infectious particles, but the mechanisms underlying this

98 bacmid DNA into Sf9 cells does not generate infectious particles, but this defect was rescued by int

99 ellow fever virus (YFV) replicon into pseudo-infectious particles by supplying the YFV structural pro

100 protein genes for production of single-round infectious particles by way of trans-complementation.

101 or through contaminated water or food by an infectious particle called a spore or oocyst.

102 Small proteinaceous infectious particles called prions cause certain neurode

103 prion strains, wherein chemically identical infectious particles cause distinct phenotypes.

104 ng that the overall architecture of the SPP1 infectious particle coevolved toward high robustness.

105 n model, prions are defined as proteinaceous infectious particles composed solely of this abnormal is

106 Despite normal structural region processing, infectious particles containing genome RNA and capsid pr

107 this method allows the facile generation of infectious particles containing wild-type, mutant, or ch

108 The risk to pick up infectious particles could be increased within this rang

109 tic effects were inhibited and production of infectious particles decreased by >1,000-fold in the non

110 al process of the emission and inhalation of infectious particles, deriving the result that that the

111 e for 46 nucleotides, was unable to assemble infectious particles, despite efficient replication.

112 ng late-cycle development yet is secreted by infectious particles during the invasion process.

113 substitution at this position, L172T, yields infectious particles following transfection at 37 degree

114 Even though conidia are the predominant infectious particle for H. capsulatum and are the first

115 ivirus structural proteins and assemble into infectious particles for presentation of lentivirus immu

116 resulting in delays in genome synthesis and infectious particle formation as well as reduced viral s

117 cleaved intracellularly to yield the mature infectious particles, formed by two polypeptides, VP33 t

118 ectivity, that the clearance of physical and infectious particles from a primary, dual-tropic virus i

119 Nevertheless, J10 failed to generate infectious particles from cells in a plasmid-based influ

120 ology became more distorted and the yield of infectious particles from inclusions declined as medium

121 standing the structure and function of these infectious particles helps elucidate the mechanism by wh

122 (infectious ORF2) which is the component of infectious particles, (ii) the secreted ORF2g (glycosyla

123 e of an L. pneumophila-infected amoeba as an infectious particle in replicative L. pneumophila lung i

124 ng that subgenomic het DNA was packaged into infectious particles in a concatemeric configuration.

125 e site is not required for the production of infectious particles in a single round of infection, but

126 ly, we observed more efficient production of infectious particles in cells expressing vesicular stoma

127 ly, we observed more efficient production of infectious particles in cells expressing vesicular stoma

128 SEOV RNA and infectious particles in culture media were detected in b

129 e DeltaUS17 mutant virus produced numbers of infectious particles in fibroblasts equal to the numbers

130 cues viral RNA replication and production of infectious particles in HSD17B12 depleted cells, support

131 CPB produced fewer infectious particles in mammalian cells than in mosquito

132 ues, we show that attenuated accumulation of infectious particles in presymptomatic disease is preced

133 ate that L. pneumophila-infected amoebae are infectious particles in replicative L. pneumophila infec

134 e plasmid in chlamydial differentiation into infectious particles in small intestine.

135 could be used as a readout of the number of infectious particles in the inoculum.

136 Sizing experiments indicated that infectious particles in vitro and in vivo were >20 nm in

137 itis C virus (HCV) permits the production of infectious particles in vitro.

138 ntration of pIII is increased, the number of infectious particles increases, and their average length

139 an previous estimates of approximately 1,000 infectious particles/infected individual.

140 e spore form of the bacterium represents the infectious particle introduced into a host.

141 In conclusion, the interior of an adenovirus infectious particle is a strongly confined and dense pha

142 ed at a high multiplicity, the production of infectious particles is largely independent of the numbe

143 ntly of the host cell genome and produces no infectious particles, is required for long-term virus pe

144 rom spherical immature forms to brick-shaped infectious particles lacking helical or icosahedral symm

145 nt plays a role for entry of in vivo derived infectious particles likely via usage of apolipoprotein

146 ctures of its RNA polymerase cofactor u2 and infectious particle, limits understanding of molecular i

147 proteins were supplied in trans, >2 x 10(6) infectious particles/ml were produced.

148 dotyped HIV-1 particles reached almost 10(6) infectious particles/ml.

149 n microscopy, the infection is weaker (fewer infectious particles), more transitory, and involves a s

150 s (MIFs) of L. pneumophila are considered as infectious particles most likely capable to cause human

151 the viral and cellular proteins that compose infectious particles of a large complex virus.

152 The endospores of Bacillus anthracis are the infectious particles of anthrax.

153 d, TNcc) replicated efficiently and released infectious particles of approximately 5 log(10) focus-fo

154 The total volume of infectious particles on the occupant's clothing immediat

155 nal SARS-CoV-2 mutant ( S-VRP) that produces infectious particles only in cells expressing a viral en

156 SARS-CoV-2 mutant (DeltaS-VRP) that produces infectious particles only in cells expressing a viral en

157 The extracellular chlamydial infectious particle, or elementary body (EB), is envelop

158 s the concentration of viral stocks to 10(9) infectious particles per milliliter or more.

159 This system produced nearly 10(3) infectious particles per ml of supernatant, equivalent t

160 This system, which produced more than 10(4) infectious particles per ml of supernatant, would be use

161 -1 envelope generate titers of less than 200 infectious particles per ml.

162 icted virus titers and increased physical to infectious particle (PFU) ratios, with additional data s

163 f a single maturation cleavage site for both infectious particle production and cell entry and emphas

164 Treatment with Quercetin reduced infectious particle production at nontoxic concentration

165 eriments to quantify viral RNA, protein, and infectious particle production during acute infection.

166 uctural genes improve genome replication and infectious particle production in mosquito cells.

167 NH-12, significantly reduces replication and infectious particle production of HCV as well as dengue

168 dification pathway, UFMylation, in promoting infectious particle production of ZIKV and DENV.

169 terminally deleted CVB3 RNAs, a decrease in infectious particle production was observed.

170 inhibition of adenoviral genome replication, infectious particle production, and cytotoxicity/oncolys

171 artha U(L)21 gene confer defects that affect infectious particle production, causing a delay in sprea

172 gy factors Atg5 or Atg7 had no effect on WNV infectious particle production, indicating that WNV does

173 viral transcription as the critical step for infectious particle production, making it a potential ta

174 haracterize the basis for this difference in infectious particle production, we constructed chimeric

175 l protein-protein interactions important for infectious particle production.

176 ortance of its C-terminal leucine residue in infectious particle production.

177 ith a dual role in viral RNA replication and infectious particle production.

178 ith a dual role in viral RNA replication and infectious particle production.

179 mal signal peptide did not enhance or reduce infectious particle production.

180 rescued dimer association, E1 transport, and infectious particle production.

181 difications D614G and R682Q further enhanced infectious particle production.

182 for protein transport, cell-cell fusion, and infectious-particle production.

183 have the ability to decrease the density of infectious particles, reducing the force of infection an

184 permissive human hepatoma cells, and minimal infectious particle release was observed.

185 nfection, suggesting that it is required for infectious particle release.

186 HCV) infections may be initiated by multiple infectious particles, resulting in a genetically heterog

187 riant differences in timing and magnitude of infectious particle shedding from index mice, both of wh

188 with asparagine abolished the production of infectious particles, suggesting that P78 may be involve

189 Each of the E2 Cys mutants produced fewer infectious particles than wild-type virus.

190 urfold-fewer particles but >1,000-fold-fewer infectious particles than wild-type virus.

191 They bind to phage tails to build infectious particles that are stored in warehouse compar

192 ls, a process required for the production of infectious particles that can lead to heritable transpos

193 t continuously phagocytose environmental and infectious particles that invade the alveolar space.

194 Prions are proteinaceous infectious particles that replicate by structural conver

195 on mechanism dominates, which results in non-infectious particles that still retain their packaged DN

196 rein virus replicates in one cell, producing infectious particles that transmit to the next cell via

197 irus (EBV) strain P3HR-1 generate subgenomic infectious particles that, unlike defective interfering

198 found that cell-free HIV-1 crosses PGECs as infectious particles, the efficiency of transcytosis is

199 say CP-delta is covalently incorporated into infectious particles, the first example of any attached

200 ential for genome packaging and formation of infectious particles, the minimal requirements of the di

201 with hepatitis B virus (HBV), in addition to infectious particles, there is an excess (typically 1,00

202 an incorporate foreign glycoproteins to form infectious particles through a process known as pseudoty

203 owing the three-dimensional structure of the infectious particle to be visualized for the first time.

204 ire 10- to 100-fold higher concentrations of infectious particles to achieve levels of gene transfer

205 believed to act as "Trojan horses" carrying infectious particles to be released on cell necrosis or

206 When a cell was infected by only a single infectious particle, variation in the kinetics of the in

207 ble in that the sizes and composition of the infectious particles vary enormously.

208 ed bacteriophages and herpesviruses assemble infectious particles via an empty precursor capsid (or '

209 cur, an infected individual needs to release infectious particles via respiratory symptoms.

210 We infected mice with spores, that is, the infectious particle, via the pulmonary route and studied

211 ss virion structure, life cycle to reproduce infectious particles, viral protein's nuclear import sig

212 cells to build a factory for assembling new infectious particles (virions), the cytoplasmic virion a

213 Infectious particles were analyzed by transmission elect

214 C. psittaci 6BC infectious particles were electroporated with various co

215 ss all of the HBV proteins and produce fully infectious particles were immunized with a mixture of li

216 tomatitis virus (VSV) ribonucleocapsids into infectious particles were investigated.

217 TNV, the levels of viral RNAs, proteins, and infectious particles were measured for 3 days posttreatm

218 cy of viral gene expression or production of infectious particles were observed.

219 rted 51 nucleotides from the 5' end of 3'CB, infectious particles were produced.

220 cant niche for viral replication, given that infectious particles were successfully isolated from ren

221 The ORF2i protein associated with infectious particles, whereas the ORF2g and ORF2c protei

222 Persistently infected mice produce de novo infectious particles, which can be inhibited with direct

223 We show here that these infectious particles, which we call propagating replicon

224 ells suppressed substantially the release of infectious particles while preserving uninfected cells.

225 r orthopoxviruses depends on the wrapping of infectious particles with a double membrane that enables

226 ulted in rapid accumulation of intracellular infectious particles with release into extracellular flu

227 from distinct serotypes can be mixed to form infectious particles with unique phenotypes.

228 DNA combined with the cell-free synthesis of infectious particles yielded virus whose mouse neuroviru