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1 y genes and a predominant M1-like macrophage infiltrate.
2 cantly negatively associated with the immune infiltrate.
3 the intratumoral localization of the immune infiltrate.
4 elial cells within a dense inflammatory cell infiltrate.
5 sociated with the tumour spheroids that they infiltrate.
6 ature and intensity of the inflammatory skin infiltrate.
7 tch1 mutant tumours have an increased immune infiltrate.
8 ose chest X-rays were obtained had bilateral infiltrates.
9 ial origin of fibroblasts within fibro-fatty infiltrates.
10 me did not require the presence of bilateral infiltrates.
11 y (CAV) is associated with intragraft B cell infiltrates.
12 clinical outcomes than those with bilateral infiltrates.
13 demonstrate an increase in neuroinflammatory infiltrates.
14 -IAB22M2C again was able to detect CD8 tumor infiltrates.
15 ortant to determine the significance of such infiltrates.
16 and fibroblasts were detected in fibro-fatty infiltrates.
17 nown as Quilty effect or nodular endocardial infiltrates.
18 dle-shaped cells with prominent neutrophilic infiltrates.
20 that vacant lands citywide may cumulatively infiltrate 51-54% additional annual rainfall volume as c
22 nance of polymorphonuclear cell inflammatory infiltrate and a reduced extent of fibrosis were observe
23 and MMPs, together with apparent mononuclear infiltrate and increased collagenolysis confirm that hyp
24 -RWE, as indicated by lung inflammatory cell infiltrate and mediators, mucus hypersecretion, and seru
26 ' was defined to quantify the in situ T cell infiltrate and was demonstrated to be superior to the AJ
27 Delta3A-infected tumors have elevated T cell infiltrates and decreased expression of the CLEC2D recep
28 atic steatosis, portal fibrosis, lymphocytic infiltrates and ductular proliferation, lobular cholesta
29 erns and spatial distribution of lymphocytic infiltrates and facilitate improved quantification of TI
30 ciated with favorable changes in immune cell infiltrates and gene expression profiles in both the gut
31 nvestigating the associations between immune infiltrates and genetic or clinical features, and four m
32 f eosinophils also exhibit robust CD8 T cell infiltrates and have a better prognosis than patients wi
33 e was similar to controls but chronic immune infiltrates and pro-inflammatory gene activation, includ
36 ained with this interface were examined with infiltrating and noninfiltrating tumors, and were compar
37 text of acute inflammation and discover both infiltrating and tissue-resident immune cells to be visi
39 lls promote a neutrophilic inflammatory cell infiltrate, and persistent arthritis, via GM-CSF product
40 were performed to test 1) whether bilateral infiltrates are associated with elevated interleukin-1 r
41 st or interleukin-8 and 2) whether bilateral infiltrates are associated with worse clinical outcomes.
43 LC) patients, and identify subtypes of tumor-infiltrated B cells and their diverse functions in the p
48 of the placenta revealed a dense macrophage infiltrate, but no evidence for the vasculopathy typical
49 caused them to form smaller tumors in mice, infiltrated by higher numbers of CD8(+) T cells that exp
54 sident CD11b/CD45(int)Ly6C(-) microglia, and infiltrating CD11b(+)/CD45(high) monocytes/macrophages c
58 depletion promoted GzmB expression by tumor-infiltrating CD4(+), and this was prevented by interleuk
59 ze was negatively associated with numbers of infiltrating CD4+ T cells, CD4+CD127+ T cells, and CD8+C
60 Carbon monoxide did not affect the number of infiltrating CD45(+) cells in the prostates of E. coli-
61 is often correlates with the number of tumor-infiltrating CD8 T cells, but many of these cells recogn
62 significantly increased the number of tumor-infiltrating CD8(+) T and natural killer cells, slowed t
64 s, a comparison of these cells with melanoma-infiltrating CD8(+) T cells revealed upregulated cytokin
68 roposed to explain how these multiple tumour-infiltrating cell types block the development of an effe
69 med an unbiased examination of diverse islet-infiltrating cells during autoimmune diabetes in the non
70 e-cell analysis of intrinsic renal cells and infiltrating cells from patients with LN is a new approa
72 mitigation of the inflammatory status of the infiltrating cells, improved electrophysiologic visual f
75 the first time complete regression of a non-infiltrating ciliary body medulloepithelioma with seedin
76 yzed by immunohistochemistry for immune cell infiltrate composition, by in situ RT-PCR and quantitati
78 the extent of connective tissue inflammatory infiltrate (CTII) using the following markers (CD4, CD5,
81 3), the most common histologic subtypes were infiltrating ductal carcinoma (IDC, 84.9%) and luminal A
85 lammatory cytokines (e.g., IL1B) from immune infiltrates, ELF3 in tumor cells was upregulated to trig
88 culating human memory T cells preferentially infiltrated ES and showed diverse functional profiles of
89 stric biopsies showed a small-sized lymphoid infiltrate, expanding the lamina propria, with a non-des
90 f deleted genes while those with high immune infiltrate expressed higher levels of adaptive resistanc
91 characterized by a lack of prominent T cell infiltrates, extensive intratumoral heterogeneity, poor
95 containing protein 3 (TIM-3) expressed by TG infiltrating gB-specific CD8(+) T cells from the HSV-1 0
96 sy-proven patient data identified as diffuse infiltrating glioma patients whose disease progressed/re
97 ignificant challenge in follow-up of diffuse infiltrating gliomas, particularly high grade, which lea
99 cell infiltration and the migratory path of infiltrating H3K27M DMG cells into other midline structu
104 umber of comorbidities (HR 5.41, P = 0.004), infiltrates (HR 3.08, P = 0.032), and neutropenia (HR 1.
106 aring BDCA-2+CD123int DC subset that rapidly infiltrates human skin wounds and comprises a major DC p
107 Finally, a higher proportion of bone marrow-infiltrating ICOShigh/PD-1- Treg cells is a highly signi
110 nd late DUX4 target genes, therefore, muscle-infiltrated immune cells may contribute the molecular la
111 nalysis of genomic, transcriptomic and tumor-infiltrating immune cell profiles demonstrated alignment
113 e tumor microenvironment (TME) that prevents infiltrating immune cells from performing their anticanc
115 examined steroid hormone receptors and tumor-infiltrating immune cells in metastatic lesions with or
119 an interferon signature in the skin without infiltrating immune cells, but with interferon-kappa pro
120 onally, by modulating the reuptake of tissue-infiltrating immune cells, lymphatics regulate immune re
121 s evaluated by immunohistochemistry in tumor infiltrating immune cells, while PD-L1 expression in the
126 ty, increased perfusion and reduced cellular infiltrate in the allograft, when compared with conventi
127 stricturing by day 16, with an inflammatory infiltrate in the neuromuscular layers including eosinop
128 epicardial thickening and dense fibro-fatty infiltrates in atrial tissue sections from patients aged
129 ajority of cells comprising the inflammatory infiltrates in kidney allografts undergoing acute and/or
131 erum proinflammatory cytokines, inflammatory infiltrates in various organs, and amyloid deposits in t
132 juvenile mice displayed a sustained myeloid infiltrate (including monocytes and neutrophils) with in
133 t the quality of the tumor-associated T-cell infiltrate informs patient prognosis in primary Merkel c
136 that this flow causes inert microspheres to infiltrate into tumour spheroids via advection from the
139 as a reduction in the number of immune cells infiltrating into the brain, mitigation of the inflammat
140 ver, 0.4% and 2.0% ripasudil reduced CD45(+)-infiltrated leukocyte frequency, Cd11b and Cd11c mRNA le
141 3 d after CMH started), apoptotic removal of infiltrated leukocytes during the remission phase was ma
142 e antigen-4 (CTLA-4), respectively, on tumor-infiltrating leukocytes eliciting immunosuppression.
143 onclusion: (18)F-FAC PET can visualize brain-infiltrating leukocytes in a mouse MS model and can moni
145 itated the targeted gene expression in tumor-infiltrating leukocytes, including antigen-presenting de
152 odel, the frequency of PD-1-expressing tumor-infiltrating LSD1-deficient CD8 T cells was greater than
155 esolution subgroup significantly depended on infiltrating lymphocyte counts, with patients who showed
156 tions between functional hypoxia imaging and infiltrating lymphocyte levels as a potential predictor
158 vestigation, we explored the effect of tumor-infiltrating lymphocyte subpopulations on lung cancer bi
159 nodal status (N0 vs rest), number of tumour-infiltrating lymphocytes (continuous variable), subtype
161 Here, we show that P2X7 activity in tumor-infiltrating lymphocytes (TIL) induces cellular senescen
162 DAC led to increased CD4(+) and CD8(+) tumor-infiltrating lymphocytes (TIL), PD1 expression, and tumo
163 en-specific, activated effector CD8(+) tumor-infiltrating lymphocytes (TILs) after interaction with t
164 d the role of CD226 in the function of tumor-infiltrating lymphocytes (TILs) and resistance to immuno
165 latory microenvironment harboring more tumor infiltrating lymphocytes (TILs) and up-regulation of inf
167 ACT) using ex vivo-expanded autologous tumor-infiltrating lymphocytes (TILs) can mediate complete reg
168 enhances the expansion and function of tumor-infiltrating lymphocytes (TILs) for treating cancer pati
169 ultifunctionality of CD8 + splenic and tumor-infiltrating lymphocytes (TILs) was impaired and associa
172 d a higher response of patient-matched tumor infiltrating lymphocytes against antigens diferentially
174 at MHC class II (MHCII) expression and tumor infiltrating lymphocytes are important prognostic factor
177 n the presence of Wnt5A-depleted MDSC, tumor-infiltrating lymphocytes expressed decreased PD-1 and LA
178 FK_pY416 staining was also observed in tumor-infiltrating lymphocytes in a subset of TNBCs with high
179 y of this tool by using it to classify tumor-infiltrating lymphocytes in breast carcinoma and cutaneo
180 ssion is increased in keratinocytes and skin-infiltrating lymphocytes of psoriatic lesions in human s
181 omeostatic myeloid cells were outnumbered by infiltrating lymphocytes which modulated the local cell-
182 clinical-pathological data on stromal tumour-infiltrating lymphocytes, PAM50 subtypes, and expression
183 18 (IL-18) pathway are upregulated on tumour-infiltrating lymphocytes, suggesting that IL-18 therapy
184 -L1 expression in both tumor cells and tumor-infiltrating lymphocytes, suggesting that immune checkpo
185 and immunohistochemical stainings for tumor-infiltrating lymphocytes, tissue-based hypoxia, and micr
188 Conditional knockout of TAK1 in microglial/infiltrated macrophages and neuronal lineages sensitizes
189 persistent DNA damage accumulation in tissue-infiltrating macrophages carrying an ERCC1-XPF DNA repai
197 ddition, our investigation showed that tumor-infiltrating MDSCs from 6 GAC patients consisted of >35%
200 onal abundance of tissue-resident microglia, infiltrating monocyte-derived macrophages, neutrophils,
202 s, including neurons, astrocytes, microglia, infiltrating monocytes/macrophages, lymphocytes, and oth
203 Here, we report that STAT3 is activated in infiltrating monocytic cells near active MS lesions and
207 phenotypic profile resembling that of tumor infiltrating myeloid and lymphoid populations, but with
208 th resulted in significantly decreased brain-infiltrating myeloid cells as well as attenuated cachexi
209 s cytometry revealed a wide heterogeneity of infiltrating myeloid cells with increased infiltration o
210 Understanding the migratory patterns of CP-infiltrating myeloid cells with intact and disrupted CX3
211 re splaying of muscle fibers by inflammatory infiltrates (n = 9) and mild fibrosis (n = 8) in the end
212 s well as the number and functions of tumour-infiltrating natural-killer and CD8(+) T lymphocytes.
214 is currently known about the origin of tumor-infiltrating nerves, how they may be recruited to tumors
215 We demonstrated in a recent study that tumor-infiltrating neutrophil density correlated with TC size.
216 rface CD62L and upregulation of Cxcr4, heart infiltrating neutrophils acquired a unique SiglecF(hi) s
221 syndrome oxygenation criteria with bilateral infiltrates on chest radiograph experience a more intens
222 days before symptom onset and had pulmonary infiltrates on imaging and whose illnesses were not attr
224 al healing at 3 days, 3 weeks, and 3 months, infiltrate or scar size at 3 weeks and 3 months, 3-day s
226 ging specific characteristics of immune cell infiltrates or aspects of the tumor microenvironment tha
227 , 95% confidence interval 1.09-2.52); >=2 mm infiltrate (OR 4.74, 2.68-8.40); and <=3 mm from corneal
228 (body temperature >38 degrees C), pulmonary infiltrates, or the need for supplemental oxygen in orde
229 mmation (glomerulitis, peritubular capillary infiltrates; p-values <=0.001) and segmental glomerulosc
231 (+) and CX(3)CR1(+) macrophages in the tumor infiltrate, paralleled by expansion of myeloid subsets e
232 ttractant pathway markedly reduced monocytic infiltrates, perineuronal nets, and autistic-like behavi
234 , including their interaction with allograft-infiltrating recipient immune cells and potential therap
235 nfiltration coincide with G1 arrest in tumor infiltrated Siah2(-/-) Tregs in vivo or following T cell
237 covered a significant heterogeneity of tumor-infiltrating slan(+) -cells, including a macrophage-like
238 d features to explain the robust lymphocytic infiltrate, such as loss of mismatch repair protein expr
239 ression correlated with varying tumor immune infiltrates suggesting that the interaction between tumo
240 mation, which is reflected by high levels of infiltrating T cells and interferon-gamma (IFNgamma) sig
242 omise in a variety of cancers, but how tumor-infiltrating T cells are activated remains unclear.
243 s the expression of CTLA-4 molecule on tumor-infiltrating T cells by siRNA-loaded chitosan-lactate (C
249 onment, including increased numbers of tumor-infiltrating T cells, elevated IFN signaling, and immune
250 ed to the downregulation of CTLA-4 on tumor -infiltrating T cells, which was associated with tumor re
254 hared antigenic epitopes recognized by tumor-infiltrating T lymphocytes (TILs) from eight melanoma pa
259 ted the involvement of virus-specific, joint-infiltrating Th1 cells as one of the main pathogenic med
260 oxygen species generation, and neutrophilic infiltrate that characterize the severe asthmatic phenot
262 In this context, the B cell phenotypes that infiltrate the central nervous system during human immun
264 uenced by virus-specific CD8(+) T cells that infiltrate the ganglia at the onset of latency and contr
265 In type1 diabetes (T1D) autoreactive T-cells infiltrate the islets of Langerhans, depleting insulin-s
268 monstrated that in steady state, neutrophils infiltrated the mouse liver following a circadian patter
269 ed by a concurrent wild-type flank infection infiltrated the TG and were retained long term, suggesti
271 subset bias was observed among GC Tfh cells infiltrating the pancreas of NOD mice, which was enhance
272 main trajectory of human slan(+) -monocytes infiltrating the tonsil tissue is toward a macrophage-li
273 nal form of EB have significantly more cells infiltrating their wounds compared with patients with re
274 ttle is known as to how comparably large NCs infiltrate this vital intracellular barrier to enter the
275 argeted elimination of ALT cancer cells that infiltrate tissues and organs to become devastating tumo
276 erculosis (ATB), and IL-35-producing B cells infiltrated to tuberculous granuloma of patients with AT
277 , comparing histological features and immune infiltrates to previously published data on human neurob
278 decreased mucus production, reduced cellular infiltrates to the lung (especially ILC2s), and decrease
281 de (Cy) transiently control tumor growth but infiltrate tumors poorly and lose function, similar to w
282 cells respond rapidly during infection, and infiltrate tumors, where they express high amounts of PD
284 somal losses of 9p21.3, as compared with non-infiltrated tumors, demonstrating how the potential inte
285 The pathology revealed diffusely and deeply infiltrating tumour cells extending through the dermis,
286 ilt and fine sand, while the particles might infiltrate up to 13 cm into sediment consisting of coars
287 the detection of intratumoral CD8(+) T-cell infiltrates upon either single or combination treatment
290 of oxygenation defect, presence of bilateral infiltrates was associated with longer duration of mecha
291 eration, necrosis, and mononuclear leukocyte infiltrates, was observed in the dorsal root, autonomic,
292 -induced lung inflammation, focal neutrophil infiltrates were increased in CGD compared with WT mice
294 olent liver metastasis from a class 1B UM is infiltrated with clonally expanded plasma cells, indicat
296 's syndrome (pSS) the exocrine glands become infiltrated with lymphocytes instigating severe damage t
297 ase symptoms was observed in silenced plants infiltrated with Pseudomonas syringae pv. tabaci express
298 tory distress syndrome but without bilateral infiltrates would have different inflammatory biomarker
300 ls are major inflammatory cells that rapidly infiltrate wounds to provide antimicrobial functions.