ライフサイエンスコーパス: infiltrative

1 th populations were highly proliferative and infiltrative.

2 SRCCR tumor configuration was ulcerative and infiltrative.

3 atory scans was classified into four groups--infiltrative, airway, vascular, or mixed.

4 otal of 46 lesions were classified by MRI as infiltrative and 81 as nodular.

5 opy workflow was employed to investigate the infiltrative and degradative ability of Fusarium oxyspor

6 lly in the context of cancer immunotherapy), infiltrative and infectious disease, and traumatic brain

7 ve in terms of growth pattern (morphea form, infiltrative and micronodular features) as compared to n

8 rm in Tlx mutant mice, these tumors are less infiltrative and rarely associate with the adult neuroge

9 icularly evident for myocarditis, whereas in infiltrative and storage diseases, the histological abno

10 HIV-HCV patients (eight of eight tumors were infiltrative and two of 27 tumors were nodular) but none

11 able to characterize the differences between infiltrative and vasogenic peritumoral regions, paving t

12 to these tumors are that they can be locally infiltrative and/or impinge on critical organs, which le

13 eneity/homogeneity, borders (well-defined or infiltrative), and intensity of contrast enhancement on

14 Glioblastomas (GBMs) are highly aggressive, infiltrative, and heterogeneous brain tumors driven by c

15 conditions, including syndromic, metabolic, infiltrative, and neuromuscular diseases, may present wi

16 features that distinguish the most malignant infiltrative astrocytoma, glioblastoma (GBM), from those

17 cal cases were associated with an underlying infiltrative astrocytoma.

18 Infiltrative astrocytomas (IAs) represent a group of ast

19 tion of these different cells yielded benign infiltrative astrocytomas, malignant astrocytomas, or tu

20 p14ARF and p16Ink4a) deletions in pediatric infiltrative astrocytomas.

21 sal cell carcinomas (nBCCs), and 1 (3.4%) as infiltrative basal cell carcinoma (BCC).

22 poptotic cells in superficial multifocal and infiltrative basal cell carcinomas, and squamous cell ca

23 atients had locally advanced, biopsy-proven, infiltrative BCC that was not amenable to surgical resec

24 of reactivated tumor suppressors and reduced infiltrative behavior.

25 sed on tumor cells is critical when treating infiltrative brain tumors such as glioblastoma multiform

26 ed efficacy in treating refractory malignant infiltrative brain tumors, and survival benefit is, at b

27 n cancers, including highly vascularized and infiltrative brain tumors.

28 The first case is an infiltrative breast cancer with occult sonography findin

29 For infiltrative breast lesions; sonography might not always

30 ression reached beyond the tumor edge, where infiltrative cancer cells are found, only for the DNA-BP

31 e markedly upregulated in GBM and many other infiltrative cancers.

32 malignancies due to its high angiogenic and infiltrative capacities.

33 Some infiltrative cardiac diseases increase ventricular wall

34 Infiltrative cardiomyopathies are characterized by the d

35 Infiltrative cardiomyopathies are often diagnosed late o

36 Infiltrative cardiomyopathies comprise a broad spectrum

37 ificantly even within the different types of infiltrative cardiomyopathies on the basis of the type o

38 ole of contemporary multimodality imaging of infiltrative cardiomyopathies, including echocardiograph

39 ion criteria were acute AR, hypertrophic and infiltrative cardiomyopathies, prior cardiac surgery, an

40 RS complex is not a uniform finding with the infiltrative cardiomyopathies.

41 -voltage QRS complex was the sine qua non of infiltrative cardiomyopathy (i.e., cardiac amyloid).

42 valuation of diffuse myocardial fibrosis and infiltrative cardiomyopathy and for functional analysis

43 related cardiac amyloidosis is a progressive infiltrative cardiomyopathy that mimics hypertensive and

44 Cardiac sarcoidosis is an infiltrative cardiomyopathy that results from granulomat

45 Cardiac transthyretin amyloidosis is an infiltrative cardiomyopathy with high mortality.

46 rupt and marked evolution of a sarcomeric to infiltrative cardiomyopathy, leading to an ominous outco

47 ac amyloidosis is an underdiagnosed cause of infiltrative cardiomyopathy, leading to heart failure ac

48 neuropathy, cardiac conduction defects, and infiltrative cardiomyopathy.

49 itoneal versus subcutaneous placement of the infiltrative catheters.

50 and increased the abundance and activity of infiltrative CD4(+) and CD8(+) T cells in KPC tumors.

51 gliomas metastasize throughout the brain by infiltrative cell migration into peritumoral areas.

52 The epigenetic encoding of these infiltrative cells mirrors that of uncommitted oligodend

53 ow here that intraocular inflammation causes infiltrative cells of the innate immune system to secret

54 opulation of genetically unstable and highly infiltrative cells that are resistant to chemotherapy.

55 m IRE increases the area and accumulation of infiltrative cells that is associated with a higher seru

56 of NgR1 expression is associated with highly infiltrative characteristics and poor survival.

57 such as tumors, hemorrhage, inflammatory or infiltrative conditions (eg, hypophysitis, sarcoidosis,

58 SEM] expression, 3.01 [0.54]; P = .005), and infiltrative cSCC (mean [SD] expression, 2.01 [0.30]; P

59 Because these tumours are highly infiltrative, current treatments that rely on targeting

60 ts can result in structural, functional, and infiltrative deficiencies of the heart muscle.

61 81% (21 of 26) to 89% (23 of 26) in cases of infiltrative disease and from 84% (16 of 19) to 100% (19

62 We demonstrate a role for EMB in suspected infiltrative disease and in the management of rare clini

63 therapies for HF caused by hypertrophic and infiltrative disease are emerging rapidly.

64 distinguishing myositis, dacryoadenitis, and infiltrative disease has workup and differential diagnos

65 iac amyloidosis is a serious and progressive infiltrative disease that is caused by the deposition of

66 Likewise, infiltrative disease that presents with a dilated left v

67 Cardiac amyloidosis is an infiltrative disease with diastolic and systolic dysfunc

68 to identify nonischemic causes (myocarditis, infiltrative disease).

69 lassified as (a) ground-glass opacity due to infiltrative disease, (b) mosaic perfusion due to airway

70 None had known infiltrative disease, hypertension of >5 years' duration

71 d tumorigenesis and increased penetrance and infiltrative disease.

72 patients may have had a primary eosinophilic infiltrative disorder that had been clinically recognize

73 lly related to an underlying inflammatory or infiltrative disorder.

74 Two women demonstrated infiltrative ductal carcinoma, and the third had prolife

75 he clinical course was the observation of an infiltrative EAE lesion in GFAP-/- mice.

76 ng of vasogenic versus the latter containing infiltrative edema, to extract a voxel-wise deep learnin

77 eurosphere cultures that enrich cells of the infiltrative edge of the tumor.

78 tcome was compared between women with deeply infiltrative endometriosis undergoing CO2 laser ablative

79 of endometrioma, as well as excision of deep infiltrative endometriosis.

80 nd death, while post-natal induction induces infiltrative epithelioid tumors, that morphologically an

81 havioral factors are associated with corneal infiltrative events (CIEs) during continuous wear of sil

82 15 years was associated with a lower risk of infiltrative events compared with teens and young adults

83 The effect of combined gene therapy on the infiltrative Fas+ CD8+ T-cell population is much less th

84 ze and morphologic structure (circumscribed, infiltrative), focality (solitary oligonodular, multinod

85 ic heterogeneity in GBM and to visualize the infiltrative front of GBM.

86 e and uncommitted developmental potential of infiltrative GBM cells.

87 ement of tumor cells and targeted therapy of infiltrative glioblastoma cells after CED.

88 In contrast, infiltrative glioblastoma growth in the absence of blood

89 could have a significant impact against the infiltrative glioma cells that are a major source of rec

90 alignant brain tumor characterized by highly infiltrative glioma cells.

91 operative pathologic confirmation of diffuse infiltrative glioma guides the decision to pursue defini

92 ehavior, response to therapy, and outcome of infiltrative glioma is challenging.

93 RH detects residual microscopic tumor at the infiltrative glioma margin and may be a promising tool t

94 nknown whether SRH of tissues taken from the infiltrative glioma margin will identify microscopic res

95 p strategies for in vivo characterization of infiltrative glioma, in order to improve disease stratif

96 who had resective surgery for supratentorial infiltrative glioma, with or without ISM.

97 Surgery for infiltrative gliomas aims to balance tumor removal with

98 practice, histology-based grading of diffuse infiltrative gliomas is the best predictor of patient su

99 C analysis in an adult cohort comprising 750 infiltrative gliomas.

100 es an aberrant and unstable IIp45 isoform in infiltrative gliomas.

101 analysis can be difficult in low-cellularity infiltrative gliomas.

102 <.003), multiple nerve involvement (P<.001), infiltrative growth (P=.01), or lymphovascular invasion

103 seful biomarkers reflecting tumor burden and infiltrative growth are available.

104 static UM corresponded to stage I histologic infiltrative growth in the sinusoidal spaces, whereas MR

105 messenger to adjacent cells and mediate the infiltrative growth of MFS, providing new insights into

106 relatively large renal mass which shows very infiltrative growth pattern on CT and MR imaging and str

107 HAE by virtue of its infiltrative growth pattern with a tendency to involve b

108 These lesions typically present infiltrative growth pattern with local invasion of adjac

109 behavior of LAM cells with respect to their infiltrative growth pattern, metastatic potential, and a

110 of different types of cancer, such as tumour infiltrative growth patterns (INF).

111 logically demonstrated stage II or stage III infiltrative growth patterns and 1 histologically demons

112 fferentiated clusters (PDCs) are features of infiltrative growth patterns and powerful independent pr

113 Magnetic resonance imaging of hepatic infiltrative growth patterns of metastatic UM correspond

114 Solid, mixed or infiltrative growth patterns were seen in grade II and g

115 erns corresponded to stage II/III histologic infiltrative growth that replaced the hepatic lobule or

116 III tumours with or without 1p/19q loss, but infiltrative growth was more common in tumours with inta

117 DH wild-type glioblastoma, display diffusely infiltrative growth, which impedes complete surgical res

118 dge-derived cells show a higher capacity for infiltrative growth, while core cells demonstrate core l

119 rance of mesenteric edema varies from a mild infiltrative haze to a severe masslike sheath that engul

120 Infiltrative HCC was found in eight HIV-HCV patients wit

121 CT revealed heterogeneous density infiltrative hepatic mass with no contrast enhancement i

122 Quantitative assessment of infiltrative heterogeneity in the peritumoral region, th

123 based markers to capture distinct aspects of infiltrative heterogeneity.

124 The biophysical mapping of infiltrative HGG potentially enables the clinical recogn

125 ied as infiltrative on MRI exhibited stage I infiltrative histologic growth patterns; of the remainin

126 Most notably, an "infiltrative" imaging phenotype was identified that pred

127 ally, mAbs could be used to target the tumor infiltrative immune cells locally, thereby eliciting a s

128 in 47 (68%) and diffuse in 22 (32%), purely infiltrative in 60 (87%) and infiltrative with superimpo

129 esentation was myositis, dacryoadenitis, and infiltrative in 67, 73, and 32 patients (39.0%, 43.0%, 1

130 Therapies for infiltrative inflammation in multiple sclerosis (MS) hav

131 lieu that may be causative and predictive of infiltrative injury and amenable to therapeutic interven

132 Their lungs developed infiltrative interstitial lesions that obliterated air s

133 Diffuse infiltrative invasion is a major cause for the dismal pr

134 Aggressive and infiltrative invasion is one of the hallmarks of gliobla

135 ute to genotoxic therapy resistance, diffuse infiltrative invasion, and immunosuppression, which are

136 he MT6-MMP-expressing tumors demonstrated an infiltrative leading edge in contrast to a rounded leadi

137 Infiltrative lesions that were hypointense on T2-weighte

138 the optimal treatment strategy for diffusely infiltrative LGGs, and the clinical management of LGGs i

139 rum or urine, distinguishing this from other infiltrative liver processes.

140 oligodendrogliomas, and class III represents infiltrative low-grade gliomas.

141 tics in plasma and CSF, neurologic function, infiltrative lung disease and systemic disease parameter

142 indings of 6 patients with CVID with nodular/infiltrative lung disease who had biopsy specimens demon

143 terstitial lung disease (also called diffuse infiltrative lung disease) encompasses a heterogeneous g

144 support the diagnosis of a different chronic infiltrative lung disease.

145 atible with the diagnosis of another chronic infiltrative lung disease.

146 manifest as fluid-filled cysts or extensive infiltrative lymphatic vessel overgrowth, often associat

147 tter disease-free survival (DFS), high tumor infiltrative lymphocyte, microsatellite instability, BRA

148 cantly among cell types, such that length in infiltrative lymphocytes > CAFs > cancer cells.

149 lls, carcinoma-associated fibroblasts (CAF), infiltrative lymphocytes, and adjacent normal epithelial

150 cytic host response to HIV-1, termed diffuse infiltrative lymphocytosis syndrome (DILS), which resemb

151 prevalence of spondyloarthritis and Diffuse Infiltrative Lymphocytosis Syndrome has decreased, where

152 studied in HIV-infected persons with diffuse infiltrative lymphocytosis syndrome, a disease in which

153 robably another manifestation of the diffuse infiltrative lymphocytosis syndrome, usually associated

154 Six patients had concomitant diffuse infiltrative lymphocytosis syndrome.

155 nias, and other complications resulting from infiltrative lymphoproliferation and autoimmunity are pr

156 mor, the profiling of somatic mutations from infiltrative malignant cells within this critical, unres

157 intrinsic pontine gliomas (DIPGs) are highly infiltrative malignant glial neoplasms of the ventral po

158 below the estimated level of the tumor in an infiltrative manner, versus injections just on top of an

159 en pathological plasticity in neurons at the infiltrative margin of glioma and suggest new strategies

160 e identification and removal of tumor at the infiltrative margin remains a central challenge.

161 tive cell numbers separately for tumor area, infiltrative margin, and distant liver stroma.

162 gy of tumors and the microenvironment at the infiltrative margin.

163 uption may be exploited for drug delivery to infiltrative margins following H-FIRE ablation.

164 to molecular and cellular composition of the infiltrative margins of GBM.

165 itary, noninvasive mass (n = 10); a dominant infiltrative mass with associated lymphadenopathy (n = 8

166 y, well-circumscribed mediastinal mass or an infiltrative mass with associated lymphadenopathy on CT

167 enforcing high levels of Wnt5a activated an infiltrative, mesenchymal-like program in classical glio

168 ut not Raf or P13 kinase, formed aggressive, infiltrative metastasis.

169 al tail-like patterns, characteristic of the infiltrative MFS.

170 m) in 1 year for BCCs containing at least an infiltrative/micronodular component and 1.06 mm (80% pre

171 erent LSF categories at univariate analysis; infiltrative morphologic structure, tumor burden greater

172 ong segment colonic stenosis and ulcerative/ infiltrative mucosa but endoscopic biopsy failed to iden

173 carditis (111), ischemic heart disease (91), infiltrative myocardial disease (59), hypertension (49),

174 mong the patients with cardiomyopathy due to infiltrative myocardial disease (adjusted hazard ratio,

175 Patients with cardiomyopathy due to infiltrative myocardial diseases, HIV infection, or doxo

176 = 12, p < 0.01), heterogeneous (n = 10), and infiltrative (n = 9).

177 The location and infiltrative nature of DMG prevents surgical resection a

178 The infiltrative nature of GBM makes complete surgical resec

179 increases in survival, likely limited by the infiltrative nature of the tumor.

180 ain the constitutive vascular remodeling and infiltrative nature of these lesions.

181 n cancers, principally because of the highly infiltrative nature of these neoplasms.

182 ghly subjective due to the heterogeneity and infiltrative nature of these tumors and depend on the sk

183 appropriate (regardless of stage) due to the infiltrative nature of thymic carcinomas.

184 oxia, metabolism, angiogenesis, invasive and infiltrative nature of tumors and potential molecular ta

185 providing new insights into the mechanism of infiltrative nature via crosstalk between tumor cells an

186 ifficult to treat, in part due to its highly infiltrative nature which contributes to the malignant p

187 approach should take into consideration the infiltrative nature, difficulty in obtaining wide margin

188 ies for gliomas fail to address their highly infiltrative nature.

189 A hallmark of astrocytic tumors is their infiltrative nature.

190 allenging brain tumors to treat due to their infiltrative nature.

191 Infiltrative NE tumor is alternatively enriched with tum

192 If an infiltrative neoplasm is highly suspected, nonenhanced a

193 genic tumor (SOT) is a rare, benign, locally infiltrative neoplasm of the jaws that appears to origin

194 rve tumors in the orbit or by metastatic and infiltrative neoplasms.

195 f these 9 lesions, 3 that were classified as infiltrative on MRI exhibited stage I infiltrative histo

196 .9%) (1 retinal vasculitis, 3 papilledema, 2 infiltrative optic neuropathy).

197 , and HMB45, and classified as exhibiting an infiltrative or nodular growth pattern.

198 Cardiac amyloid deposition leads to an infiltrative or restrictive cardiomyopathy and is the ma

199 elping distinguish HCM from phenocopies like infiltrative or storage diseases and detecting myocardia

200 be identified and treated, such as valvular, infiltrative, or pericardial disease.

201 s for surgical treatment included non-deeply infiltrative oropharynx tumors, minimal soft palate invo

202 However, the infiltrative pattern of invasion of oral squamous cell c

203 ts had a larger volume, showed more often an infiltrative pattern, and was detected outside specific

204 sters in a perivascular and subpial cellular infiltrative pattern, geographic necrosis and infiltrati

205 airpin RNA dramatically blocked the cellular infiltrative pattern, hypervascularity, and cell prolife

206 lt to diagnose because of its subtle elusive infiltrative pattern.

207 ne cells in particular often display complex infiltrative patterns, however, there is a lack of quant

208 nic acid (MAL-PDT) and the tumors acquire an infiltrative phenotype and became histologically more ag

209 The infiltrative phenotype did not accumulate (11)C-MET and

210 insufficient for early detection due to the infiltrative phenotype of diffuse-type cancers.

211 ls, histologic sections of lung demonstrated infiltrative pneumonia and lung homogenate cultures grew

212 of <15 months, primarily as a result of high infiltrative potential and development of resistance to

213 ortant role for a tumor's aggressiveness and infiltrative potential.

214 ct in the middle esophagus concerning for an infiltrative process with full thickness tear.

215 group of rare conditions characterized by an infiltrative process, abnormal gas exchange, and restric

216 renal ultrasonography, strongly suggested an infiltrative process.

217 g remodeling associated with inflammatory or infiltrative processes results in displacement, destruct

218 The diffusely infiltrative properties of GBM result in residual tumor

219 ains largely incurable because of its highly-infiltrative properties.

220 al regulation and in the determination of MG infiltrative properties.

221 ts were delivered in periresectional (tumour-infiltrative) regions, on any of the first 3 days of a 2

222 atment and chemotherapy, MG cells are highly infiltrative, rendering focal therapies ineffective.

223 respiratory symptoms, eosinophil count, and infiltrative shadow diminished.

224 ory symptoms and eosinophil count, while the infiltrative shadow remained.

225 pped, the eosinophil count increased and the infiltrative shadow returned.

226 ome of any rheumatological, inflammatory, or infiltrative skin condition occurred in 123 vs 384180 bi

227 oad set of rheumatological, inflammatory, or infiltrative skin conditions and for stillbirth or neona

228 der set of rheumatological, inflammatory, or infiltrative skin conditions from birth were identified.

229 and their receptors during T-cell autoimmune infiltrative skin diseases.

230 tent, biopsy-proven Riedel's thyroiditis and infiltrative soft tissue along the right atrial wall and

231 s were identified as nodular, plaquelike, or infiltrative soft-tissue lesions in the peritoneal fat o

232 c examination revealed a higher incidence of infiltrative subtype in the exenterated group (P = .0001

233 excision, or pathologic analysis reveals an infiltrative subtype.

234 ater differences between vasogenic edema and infiltrative tissue and training a convolutional neural

235 G glioma) was the stiffest, whereas the most infiltrative tumor (MDA-MB-231 metastatic breast carcino

236 1: OR, 5.10; 95% CI, 2.30-11.27), increased infiltrative tumor border (OR, 1.03; 95% CI, 1.01-1.04),

237 rup-Makinen inflammatory score, desmoplasia, infiltrative tumor border, tumor necrosis, and tumor-to-

238 Infiltrative tumor growth into adjacent soft tissues is

239 umor thickness, increasing mitotic rate, and infiltrative tumor growth pattern were significantly ass

240 t glioma phenotypes, including the diffusely infiltrative tumor margin and angiogenic core.

241 even higher amounts deposited in regions of infiltrative tumor, resulting in useful T(1) contrast la

242 menting the routine microscopic diagnosis of infiltrative tumors and both can be used in paraffin sec

243 The extent of the infiltrative tumors could be observed by MRI but with lo

244 Anaplastic gliomas are infiltrative tumors, and their ability to migrate throug

245 i-positive gastric MALT lymphomas, including infiltrative tumors, may respond to antibiotics.

246 ole in the invasiveness of gliomas and other infiltrative tumors.

247 e molecules, which would result in increased infiltrative tumour growth along the blood vessels.

248 17 xenografts which demonstrated a diffusely infiltrative tumour growth pattern similar to human DIPG

249 ch may putatively be associated with the GBM infiltrative tumour margin.

250 Growth patterns (solid : mixed : infiltrative), tumour-margin transitions in cellularity

251 re mainly multilobulated, heterogeneous, and infiltrative tumours.

252 quently present at radiologic diagnosis with infiltrative-type HCC and portal-obstructing tumors, whi

253 robabilities of death at 12 months of 87% in infiltrative-type HCC, 32% in multiple-nodule type, and

254 al aneurysms and dissection, telangiectasia, infiltrative vascular disease, and inherited tumors and

255 ement, necrosis, contrast-to-necrosis ratio, infiltrative versus edematous T2 abnormality, mass effec

256 Two tumor phenotypes (angiogenic and infiltrative) were obtained.

257 2 (32%), purely infiltrative in 60 (87%) and infiltrative with superimposed masslike nodules in nine