ライフサイエンスコーパス: inflict

1 r protect their tissues from the damage they inflict.

2 and deformity that scoliosis can insidiously inflict.

3 n during the insult that an injury was being inflicted.

4 lative to rFVIII after tail vein transection inflicted 24 hours after dosing.

5 ost needlestick or sharps injuries were self inflicted (711 [87%] of 817) and involved a hollow-bore

6 blic goods are equally accessible to all but inflict a fitness cost on individual producers is a long

7 sume that moderately destabilizing mutations inflict a fitness penalty proportional to the reduction

8 udies whereby people can pay a small cost to inflict a heavy loss on a punished individual.

9 d particularly their different combinations, inflict a heavy toll on crop productivity worldwide.

10 raction whereby both cell types co-exist and inflict a minimal degree of harm on each other.

11 can adapt to poultry and mammalian species, inflicting a great socioeconomic burden on farming and h

12 plant viruses that infect many field crops, inflicting a heavy global economic burden.

13 y tract in the majority of patients, without inflicting a high radiation dose on the patient.

14 ethods commonly isolate and sacrifice cells, inflicting a perturbed state and preventing complementar

15 We suggest that IL-23 inflicts a repurposing of the adaptive cytotoxic effecto

16 Respiratory syncytial virus (RSV) inflicts a significant toll on human life.

17 us influenzae, and Streptococcus pneumoniae, inflicts a substantial burden of disease worldwide.

18 derstanding about how children present after inflicted abdominal or skeletal trauma.

19 ulfate sodium (DSS), and the severity of the inflicted acute colitis was determined.

20 Here, we find that inflicting acute lung injury (ALI) to mice doubles their

21 live pathogen often impairs DC function and inflicts additional damage on the host.

22 CD4 and CD8 T cells do have the capacity to inflict adjacent tissue damage and that this injury is g

23 ich secretes AMPs, can remain immune to self-inflicted AMP-induced apoptosis.

24 nt to M. haemolytica-caused pneumonia, which inflicts an economic loss of over $1 billion to the US c

25 Malaria inflicts an enormous burden on global human health.

26 ichia coli (ETEC), an E. coli pathotype that inflicts an enormous global disease burden.

27 ion in FRH was driven by a reduction in self-inflicted and undetermined injuries.

28 s slides, a 3-mm-wide wound was mechanically inflicted, and wound fill on days 4, 6, and 9 was report

29 r (Tfh) cells, whose excessive responses can inflict antibody-mediated autoimmunity.

30 In accordance, HlyA was unable to inflict any [Ca(2+)]i oscillations in 132-1N1 cells, whi

31 ed films can be accurately evaluated without inflicting any damage to the films.

32 tial studies are the result of cycloheximide-inflicted artifacts.

33 We conclude that cerebellar damage inflicted at a young age is not necessarily better compe

34 ) T cells, and inhibit tumour growth without inflicting autoimmunity.

35 e to acceleration of beta amyloidosis in HIV-inflicted brains, and modulation of macrophages may be a

36 and there is much interest in how such self-inflicted breaks are effectively managed.

37 infection in a 21-year-old male after a self-inflicted burn injury.

38 mably to fine-tune activity and limit damage inflicted by activated RPS4 protein.

39 ut protect the opposite pole from the damage inflicted by another, immediate application of SW.

40 mmunosuppression protocols, allograft damage inflicted by antibody specific for donor organs continue

41 Clonal loss-of-function, inflicted by blastomere transplantation or gene-transfer

42 ed differences in the transcriptomic changes inflicted by both pathogens as a first step to character

43 ling molecule able to amplify the cell lysis inflicted by certain bacterial toxins including the two

44 w perspective for the potential health risks inflicted by endogenous formaldehyde and may inform impr

45 and predicting the biological perturbations inflicted by exposure to nanoparticles (NPs).

46 The renal injury inflicted by expression of the folding mutants was marke

47 The moderate and mild traumatic injury was inflicted by focal laser lesion and by mild photo-damage

48 ems to build a science of repairing the harm inflicted by humans on natural environment.

49 ation, thus exclusively counteracting damage inflicted by immune responses.

50 t regulators to protect the self from damage inflicted by inadequate complement activation.

51 Specifically, leaf damage inflicted by insect herbivory or mechanical wounding at

52 -strand breaks (DSB), the most lethal lesion inflicted by IR.

53 el factors required for repair of DNA damage inflicted by IR.

54 By contrast, after chronic injury inflicted by iterative hepatotoxin (carbon tetrachloride

55 ted deaths (i.e., fatalities due to injuries inflicted by law enforcement officers) undercount these

56 tosis in response to injuries, such as those inflicted by macrophage-produced TNF alpha and NO.

57 e therapeutics to counter the high mortality inflicted by malaria.

58 Funnel-web envenomations are mostly inflicted by male spiders that wander from their burrow

59 hat helps tumor cells survive the DNA damage inflicted by many chemotherapy agents.

60 the same time repairing the vascular damage inflicted by neutrophil activation, thereby maintaining

61 impact injury, and rats with vascular injury inflicted by photothrombosis.

62 etected in model systems of lysosomal damage inflicted by proteopathic tau and during phagosome paras

63 hat aging is largely due to molecular damage inflicted by reactive oxygen species, electrophiles, and

64 Lung injuries inflicted by recurring infection and excessive inflammat

65 n loss in three non-coding nucleic acids was inflicted by replacement of a duplex stem with unstructu

66 lling, and RNA repair neutralizes the damage inflicted by ribotoxins for cell survival.

67 rrier defect aggravated by mechanical injury inflicted by scratching, a T(H)2 cell-dominated immune r

68 Collectively, data suggests that DSBs inflicted by SecA2 secretome of Mtb provides survival ni

69 tRNA anticodon damage inflicted by secreted ribotoxins such as fungal gamma-to

70 Their ability to promptly respond to insults inflicted by stress-causing microbes strongly suggests t

71 Damage inflicted by such sPLA(2)s (beta-ntx) on neuronal mitoch

72 ention for reversal of impaired neurogenesis inflicted by Tat and cocaine.

73 tRNA damage inflicted by the Escherichia coli anticodon nuclease Prr

74 y influenza virus, mirroring the destruction inflicted by the highly pathogenic 1918 'Spanish' influe

75 DNA repair systems to repair the DNA damage inflicted by the host during infection, but the role of

76 e-enhancing response to bacterial DNA damage inflicted by the host immune system.

77 DNA repair pathways to resist genomic damage inflicted by the host.

78 CSC-treated pigs, indicating that the damage inflicted by the infarct in the 2 groups was similar; 1

79 haracteristics, but neither explained damage inflicted by the other.

80 susceptible to endolysosomal membrane damage inflicted by the pathogens and noxious particles they in

81 of physical, emotional, and sexual violence inflicted by their spouses.

82 nd-organ targeting Abs, the extent of damage inflicted by these Abs may be heavily dependent on cues

83 ceptibility to grazers, but allocation costs inflicted by this plastic morphological defense are poor

84 Importantly, when administered to mice inflicted by TLR2, but not TLR4-driven lethal inflammati

85 this study, we examined the types of injury inflicted by tropilaelaps mites on different stages of h

86 lored and thus the tremendous disease burden inflicted by type 2 diabetes alleviated.

87 ole in preventing autoimmunity and pathology inflicted by uncontrolled immune responses to infections

88 o reveal and analyze gene expression changes inflicted by various physical and chemical environmental

89 can reduce the amount of punishment actually inflicted, by "tipping" a situation from its high-violat

90 luenza infection, reduces tissue repair, and inflicts caspase-dependent disease pathology.

91 of H(2)O(2) reactive oxygen species (ROS) to inflict cell death in MDA-MB-231 cells, demonstrating th

92 of prosurvival factors restrained infection-inflicted cell death and that exacerbated cell death pro

93 duce apoptosis as a secondary consequence of inflicting cell damage.

94 Like wild type, stv1Delta was able to inflict cellular damage in Caco-2 and macrophage cells,

95 ARs trigger multiple deleterious cascades to inflict cellular damage on both neurons and glia during

96 en to form reactive oxygen species (ROS) and inflict cellular damage, the biogenesis of Fe-S clusters

97 damaging macrophage functions, they directly inflict cellular injury within the arterial wall.

98 activity of both fusion partners and without inflicting chemical damage on the proteins to be joined.

99 ctivated while minimizing their potential to inflict collateral damage to the adjacent lung tissue an

100 nt that antisocial children often grow up to inflict considerable damage on others at a high cost, an

101 humans unnoticed for years or even decades, inflicting continuous damage that can culminate later in

102 ently developed a device that can be used to inflict controlled head injury to flies, resulting in ph

103 Individuals with enhanced abilities to inflict costs (e.g., stronger individuals) or to confer

104 It involves inflicting costs on defectors; and though the costs for

105 rpersonal negotiating tactics (conditionally inflicting costs or conditionally withholding benefits)

106 This finding suggests that inflicting costs without generating benefits does not re

107 These then inflict cytotoxicity through downstream activation of th

108 ey invade, and they use neurotransmitters to inflict damage and create room for growth.

109 rop: a nearby supernova explosion that could inflict damage by accelerating cosmic rays that can deli

110 We report here that viruses that do not inflict damage on beta cells provided protection from T1

111 y, ischemia can also induce this pathway and inflict damage on native cells.

112 ructure closely related to ceramide, did not inflict damage.

113 ey protect themselves from GrB-mediated self-inflicted damage are unknown.

114 fitness by protecting symbiosis against host-inflicted damage during development and by controlling p

115 ionary adaptation allowing DHP to avoid self-inflicted damage in the oxidative environment.

116 w such trade-offs impact sub-lethal pathogen-inflicted damage, and whether these trade-offs even occu

117 from progenitors that are refractory to self-inflicted damage, rather than derived from fully differe

118 ttle is known about how bacteria escape HOCl-inflicted damage.

119 opper in reaching vital destinations without inflicting damage or becoming trapped in adventitious bi

120 zed reaction under native conditions without inflicting damage to the target membrane or cell.

121 e been recognized to participate in the self-inflicted damaging immune responses that characterize au

122 the dramatic increase in the number of self-inflicted deaths from suicide, alcohol-related liver dis

123 period characterised by a sharp rise in self-inflicted deaths.

124 se of malaria outside sub-Saharan Africa and inflicts debilitating morbidity and consequent economic

125 These results indicate that the tumor-inflicted deficits of TILs are reversible.

126 Modern war ballistics and blast injuries inflict devastating extremity injuries, violating soft t

127 ite manages to infect, invade and ultimately inflict devastating tissue destruction.

128 hly malignant paediatric brain tumour, often inflicting devastating consequences on the developing ch

129 riggers harmful inflammatory responses as it inflicts direct tissue damage.

130 sm rupture and subarachnoid hemorrhage (SAH) inflict disability and death on thousands of individuals

131 factors and hijacks the rice BR machinery to inflict disease.

132 and peroxynitrite close to the cell nucleus, inflicting DNA damage, but the source of reactive oxygen

133 rn impairs proper chromosome segregation and inflicts DNA damage on the daughter cells.

134 iate homolog segregation and arise from self-inflicted double-strand breaks (DSBs).

135 discharge following adversity-related (self-inflicted, drug-related or alcohol-related, or violent i

136 sion with adversity-related injury (ie, self-inflicted, drug-related or alcohol-related, or violent i

137 suggest that the animal models tested do not inflict DSBs on the mycobacterial chromosome, that other

138 d showed that other predominant immune cells inflicted during A. hydrophila infections, such as murin

139 breaks with 2',3'-cyclic-PO4 and 5'-OH ends inflicted during tRNA splicing and non-canonical mRNA sp

140 Imaginal disc damage inflicted early in larval development triggers developme

141 ouse colitis model, we found that Salmonella-inflicted enteropathy elicits parallel blooms of the pat

142 However, it is difficult to assess damage inflicted exclusively by DSAs when alloreactive T cell a

143 tment condition where peer punishment can be inflicted exclusively on members of the same generation

144 Urinary tract infections (UTIs) inflict extreme pain and discomfort to those affected an

145 Although these dose rates are estimated to inflict fewer than a single DNA double-strand break (DSB

146 More specifically, we assume that mutations inflict fitness penalties proportional to the extent tha

147 es the intracompartmental pressure of CS but inflicts further tissue damage.

148 squamous cell carcinoma (SCC) genesis should inflict genomic alterations not only on the epithelium b

149 erties of automotive engines, where bearings inflict greater forces on the crankshaft when operated u

150 ily attacked unfamiliar B6 female intruders, inflicting >40 bites in a 5-minute encounter.

151 Self-inflicted gunshot wounds (SIGSWs) are a common method of

152 -old woman with a history of repetitive self-inflicted handheld laser exposure was found to have bila

153 er retinal streaks were associated with self-inflicted handheld laser injury.

154 is generally defined as incurring a cost to inflict harm on a wrong-doer.

155 o challenge the perceived power of voices to inflict harm on the voice hearer if commands are not fol

156 ionary trade-off between amounts of pathogen-inflicted harm and how effectively viruses position them

157 sively satisfied retributive motives by only inflicting harm on the transgressor, or additionally sat

158 p's intrinsic capabilities and resources for inflicting harm.

159 ncluding sexual abuse, physical child abuse, inflicted head trauma, and child abuse prevention.

160 eter-related bloodstream infections (CRBSIs) inflict health impairment and high costs.This study inve

161 he Plasmodium falciparum malaria parasite to inflict high morbidity and mortality on human population

162 However, Nva mistranslation inflicted higher toxicity than Val, in agreement with Il

163 tentially limiting the propensity of HOCl to inflict host tissue damage that can lead to inflammatory

164 rogresses with self-propagating cancer cells inflicting host-tissue damage.

165 membrane oxidation and enters the cytoplasm inflicting hydroxyl radical attack on intracellular prot

166 expensive monoclonal antibodies, which often inflict immune-related adverse events.

167 n, we show that an environmental disturbance inflicted in early gestation can induce subtle cytoarchi

168 mergency departments were attributed to self inflicted injuries among children (26,045 males and 51,3

169 cy department visits (ED) attributed to self inflicted injuries and attempted suicides among children

170 y potential methods of such intentional self inflicted injuries and attempted suicides.

171 Self inflicted injuries by poisoning were the most frequently

172 to 2013 with the admitting diagnosis of self-inflicted injuries via firearms.

173 an External Cause of Injury for any of self inflicted injuries were selected.

174 cide were current and past diagnoses of self-inflicted injuries, major depression, bipolar disorder,

175 Limitation: Exclusion of self-inflicted injuries, misclassification of intent, and asc

176 r proportion of ED visits attributed to self inflicted injuries.

177 notin compounds, and is known to selectively inflict injury to specific regions of the brain.

178 causes of death were overdose (57.9%), self-inflicted injury (13.2%), trauma/accidents (10.5%), and

179 sks of suicide were increased following self-inflicted injury (adjusted subhazard ratio 5.11 [95% CI

180 larly after any drug/alcohol-related or self-inflicted injury (i.e., with/without violent injury), fo

181 of the immune system can also result in self-inflicted injury culminating in autoimmune and allergic

182 n for violent, drug/alcohol-related, or self-inflicted injury have increased risks of subsequent harm

183 s also paid to the importance of considering inflicted injury in the differential diagnosis of every

184 eir supporting functions while avoiding self-inflicted injury is poorly understood.

185 practice to reduce risks of harm after self-inflicted injury should be extended to drug-related or a

186 jury (violent, drug/alcohol-related, or self-inflicted injury) has been described as a "teachable mom

187 s of violent, drug/alcohol-related, and self-inflicted injury, but particularly after any drug/alcoho

188 Once considered a self-inflicted injury, pancreatitis is now recognized as a co

189 anzyme B (GrB), Spi6 protects CTLs from self-inflicted injury.

190 jury (violent, drug/alcohol-related, or self-inflicted injury; n = 333,009) or for accident-related i

191 the protective pain pathway of predators by inflicting intensely painful stings.

192 f age and among those with unintentional and inflicted (intentional) injuries also showed no differen

193 se the midgut via an intracellular route and inflict irreversible damage to the invaded cells.

194 their activity or, when released in excess, inflict irreversible damage.

195 at photobleaching is a necessary step toward inflicting irreversible biological damage.

196 ns open pathways for neighboring networks to inflict large cascades.

197 ty to metabolites and/or drug molecules, and inflicts large-scale changes in metabolism.

198 In contrast, accidental and peer-inflicted laser injuries were found to result in focal f

199 d loss on spectral-domain OCT following peer-inflicted laser injury.

200 especially in livers exposed to agents that inflict lasting mutagenic DNA damage.

201 especially in livers exposed to agents that inflict lasting mutagenic DNA damage.Oncogene advance on

202 nd radioembolization with use of yttrium 90, inflict lethal insult to tumors while preserving normal

203 al cancer therapy is a promising new tool to inflict localized and irreversible damage to tumor tissu

204 n of lung injury from a form of patient self-inflicted lung injury.

205 ibitor, had increased susceptibility to self-inflicted lysis because of increased NE activity.

206 that could be used in a bioterror attack to inflict mass casualties.

207 be virulent parasites with the potential to inflict mass mortalities on hosts, causing e.g. changes

208 loid cells, DRP1 or MMP12 suppression in ALI-inflicted mice repress arterial stress and brake MMP12 r

209 stant obese db/db mice or lipopolysaccharide-inflicted mice were associated with increased FoxO1 prod

210 ntly decreased Th but increased Tregs in EAE-inflicted mice, without apparent global immune suppressi

211 The Drosophila TBI (dTBI) device inflicts mild, moderate, or severe brain trauma by preci

212 , a neurodegenerative movement disorder that inflicts millions worldwide.

213 ly deadly, this form of malaria continues to inflict misery on the millions of sufferers who have bee

214 (o)ortho - G(o)H or G(o)ortho - G(o)para) by inflicting molecular strain and consequently weakening t

215 glycolipid agonist of iNKT cells reduced SEB-inflicted morbidity/mortality.

216 sly generated as by-products of respiration, inflict more damage on the mitochondrial (mt) than on th

217 pathological inflammatory responses that can inflict more harm than the infection itself.

218 n indicates that neither high levels of lion-inflicted mortality nor behavioural avoidance inflict su

219 s in which the top predator is a generalist, inflicting mortality upon the focal prey species, but it

220 Reactive oxygen species (ROS) inflict multiple types of lesions in DNA, threatening ge

221 Despite our ability to experimentally inflict mutations at will, it remains difficult to link

222 ent therapeutic strategies for these disease-inflicting mutations.

223 umer satisfaction, intensive meat production inflicts negative externalities on public health, the en

224 omarkers may be used as a screening tool for inflicted neurotrauma.

225 Collapsing structures and swirling debris inflict numerous crush injuries, fractures, and serious

226 e examined what damage Th17 cell lines could inflict on allogeneic skin grafts in the absence of othe

227 ns from modifications the virulence proteins inflict on host target proteins.

228 se of the devastating diseases these viruses inflict on humans, animals, and plants.

229 of cells to damage that environmental forces inflict on macromolecules.

230 rld are much more than the collateral damage inflicted on civilians, infrastructure, environment, and

231 he frequency of extreme R(onset), calamities inflicted on coral reefs by the warming oceans may exten

232 The injuries inflicted on different developing honey bee stages were

233 Continuous oxidative damage inflicted on DNA produces 7,8-dihydro-8-oxoguanine (8-ox

234 lenging due in part to the continuous damage inflicted on DNA, which results from its contact with re

235 amines may repair some of the damage that is inflicted on protein amines by HOCl.

236 reaction is identical whether the injury is inflicted on skin and muscle or also involves a bone def

237 ortant issues regarding the potential damage inflicted on the analyzed samples.

238 investigated in excisional wounds that were inflicted on the back skin of control and mice lacking i

239 mical difference may be attributed to damage inflicted on the central pattern generator of locomotion

240 ity of data on the extent of molecular scars inflicted on the mouse genome.

241 The damage inflicted on the myocardium during acute myocardial infa

242 mechanical properties by healing the damage inflicted on them have great potential for applications

243 Surprisingly, elevated temperatures inflict opposite effects on phyB's functions in the hypo

244 n these circumstances is not attributable to inflicted or accidental trauma.

245 a lipopeptide-like sequence (C10OOc12O) that inflicted outer membrane damage at a low micromolar rang

246 rious stimuli, but if left unchecked, it can inflict oxidative damage on all types of biological macr

247 rous acid (HOCl) at sites of inflammation to inflict oxidative damage upon invading pathogens.

248 rms reactive chlorinating species capable of inflicting oxidative stress and altering protein functio

249 dopamine precursor levodopa on decisions to inflict pain on oneself and others for financial gain.

250 dowed with an ability to chase, capture, and inflict pain.

251 that most people show a greater aversion to inflicting pain on others than themselves.

252 rated into human conflict, with the goals of inflicting pain, destroying food, and transmitting patho

253 der in which sexual pleasure is derived from inflicting pain, suffering, or humiliation on others.

254 eptor 1 ligands suppress all features of flu-inflicted pathological inflammation and place the endoth

255 ated proteins may be a general mechanism for inflicting pathological conditions in various diseases.

256 uctural variants that can fuel evolution and inflict pathology.

257 ly used broad-spectrum antibiotics, but they inflict permanent hearing loss in up to ~50% of patients

258 the adaptations that allow scolopendrids to inflict physical damage on prey and predators.

259 When wound-inflicted prepupae metamorphosed to white-eyed pupae, al

260 Our data showed that ISO administration inflicts pro-oxidative changes in heart by stimulating p

261 strates the ability of tropilaelaps mites to inflict profound damage on A. mellifera hosts.

262 honor patient autonomy against a concern of inflicting psychological harm.

263 ition of this beta-emitting scout dose could inflict radiation damage, the extent of which we aimed t

264 bris and promotes tissue repair, but it also inflicts secondary injury from inflammatory responses.

265 hils eliminate pathogens efficiently but can inflict severe damage to the host if they over-activate

266 In field experiments, elephants inflicted severe damage on whistling-thorn trees from wh

267 ltiple arms of the host immune response, and inflicting severe damage to mucosal barriers, resulting

268 ally significant invasive species capable of inflicting severe feeding damage on many important tree

269 inity (NaCl) stress impairs plant growth and inflicts severe crop losses.

270 , or cocaine exclusively, or repeatedly self-inflict shocks.

271 jority of pediatric respiratory diseases and inflict significant economic loss, health care costs, an

272 s) are prevalent among diabetic patients and inflict significant morbidity and mortality.

273 Psoriasis and psoriatic arthritis inflict significant morbidity.

274 Qualitative evidence suggests that hirsutism inflicts significant negative impacts on quality of life

275 Mice lacking Bhlhb5 develop self-inflicted skin lesions and show significantly enhanced s

276 ct on the S-phase of T. brucei cell cycle by inflicting specific damage on the kinetoplast.

277 ions in which nature provides restoration or inflicts stress, and transactions that are more mutual,

278 enal gland, and its degradation products can inflict substantial protein damage via formation of adva

279 To address this issue, we inflicted substantial DG-specific damage in mice of eith

280 nflicted mortality nor behavioural avoidance inflict sufficient demographic consequences to translate

281 situation where participants freely chose to inflict the same harms.

282 e mechanism(s) by which oxidative DNA damage inflicts the genome.

283 ens and indirectly limit immune inflammation-inflicted tissue damage by employing multiple mechanisms

284 We find that massive damage inflicted to the posterior or the dorsal compartment of

285 een modeled in Drosophila using devices that inflict trauma on multiple parts of the fly body, includ

286 ith firearms (OR = 9.15, p < 0.001) and self-inflicted trauma (0.7%) also with firearms (OR = 44.66,

287 01) and TBI (OR = 1.54, p = 0.048) from self-inflicted trauma and mortality (OR = 2.08, p < 0.001) fr

288 tional trauma in the youngest group and self-inflicted trauma in the oldest group.

289 6) years and assault 12.3(8.1) years to self-inflicted trauma, 17(3.4) years.

290 he evaluation of unexpected infant death and inflicted traumatic brain injury are ongoing.

291 atment, including physical and sexual abuse, inflicted traumatic brain injury, and child neglect.

292 misconduct and consequential harms have been inflicted upon American Indian/Alaska Native communities

293 e burden of disease, death and economic loss inflicted upon the tropical world by this parasite.

294 nse of myeloid cells to inflammatory stress, inflicted via intraperitoneal administration of sodium c

295 hrough the damage that these large parasites inflict when migrating through host tissues.

296 Closed head TBI was inflicted with a mechanical device that subjects flies t

297 s, South Africa afford being thrown so as to inflict worthwhile damage to a medium-sized animal over

298 sharply decrease at the margins of a freshly inflicted wound to increase again as healing begins.

299 igin of postoperative pain is the surgically inflicted wound, there is appeal to localized applicatio

300 t such breaks may explain the puzzling 'self-inflicted wounds' at the ends of the Mos1 transposon in