ライフサイエンスコーパス: informatics

1 ea of bioinformatics can be called 'bioimage informatics'.

2 osphorylation of Shp2 (Ptpn11 - Mouse Genome Informatics).

3 aterials science, biomaterials, and clinical informatics.

4 rs access to, and training in, proteogenomic informatics.

5 or a very important problem in translational informatics.

6 atment, and for extending the field of image informatics.

7 ased healthcare and genotype-meets-phenotype informatics.

8 nisms demonstrate the importance of bioimage informatics.

9 applications in drug discovery and molecular informatics.

10 gnancy and arrhythmias, quality of life, and informatics.

11 important component of clinical microbiology informatics.

12 Quantitative Insights Into Microbial Ecology informatics.

13 ignificance of these advances for biomedical informatics.

14 r a variety of technologies from medicine to informatics.

15 at can be applied across protein engineering informatics.

16 of growth in PSP are in disease and isoform informatics.

17 search is a defining challenge in biomedical informatics.

18 ironment, and eventually arriving in medical informatics.

19 n and 1-2 d for data analysis and downstream informatics.

20 New technological and informatics advancements in population genomics are bein

21 Recent technological and informatics advances have led to unprecedented volumes o

22 We sought to determine whether an informatics algorithm applied to the EHR could electroni

23 An informatics algorithm can successfully identify both kno

24 We developed an informatics algorithm to search the EHRs of patients age

25 rm effect on productive BKPyV infection, our informatics analyses indicate that the preferred target

26 Informatics analyses reported here show that RNA granule

27 Subsequent informatics analyses revealed a network of injury-respon

28 Using integrated informatics analyses, we constructed putative regulatory

29 ts with the prediction of vaccine targets by informatics analysis of genome sequences.

30 An unsupervised informatics analysis revealed that immune response and i

31 he development of experimental protocols and informatics analysis tools is helping to reduce sequenci

32 abilities, approaches, and tools of bioimage informatics and apply them to advance their own studies.

33 s as single-photon light sources for quantum informatics and biolabels for real-time monitoring of si

34 s, previous knowledge from proteomic pathway informatics and cell signaling models to delineate key t

35 Here we use mass spectrometry informatics and data visualization approaches(11-13) to

36 The workflow integrates group theory, informatics and density-functional theory to uncover des

37 he past decade, its application in molecular informatics and drug discovery is still limited.

38 of compounds have a long history in chemical informatics and drug discovery.

39 wing for deep characterization for molecular informatics and drug discovery.

40 s between entomology and disciplines such as informatics and electrical engineering.

41 This combined informatics and functional approach has allowed the char

42 Comprehensive informatics and functional studies revealed a compartmen

43 tegrated with the other data in Mouse Genome Informatics and interconnected with other databases, pla

44 als, the International Journal of Functional Informatics and Personalized Medicine and the Internatio

45 sign and International Journal of Functional Informatics and Personalized Medicine, IEEE 7th Bioinfor

46 ta may be leveraged with novel technologies, informatics and practical clinical paradigms to apply th

47 netic screens has created the need for clear informatics and statistical approaches to deal with the

48 Clinical informatics and structured accessible secure data captur

49 , EBI's Ontology Working Group, Mouse Genome Informatics and the Monarch Initiative among others, and

50 e for pipetting, non-trivial tasks for which informatics and visualization tools can prevent costly e

51 tervention combining professional education, informatics, and financial incentives reduced the rate o

52 d here is a framework for the unification of informatics- and physics-based data associated with DNA,

53 ecognition algorithms are useful in bioimage informatics applications such as quantifying cellular an

54 Here we present an informatics approach based on Boolean logic to identify

55 derived peptides were predicted by an immuno-informatics approach based on the HLA-A*02 binding motif

56 derived peptides were predicted by an immuno-informatics approach based on the HLA-A2 binding motif.

57 The informatics approach increased the number of products co

58 This new translational biomedical informatics approach supports not only detection of new

59 We introduce an informatics approach that uses publicly available data t

60 An informatics approach to evaluating combined chemical exp

61 To use an informatics approach to examine the association of ADT a

62 dy is to optimize an integrated experimental/informatics approach to more confidently characterize th

63 A lipid-mediator informatics approach was employed to systematically iden

64 Here, employing an informatics approach, we define novel families of T6S pe

65 88 individuals with prostate cancer using an informatics approach.

66 features it produces regulate the downstream informatics approach.

67 Two informatics approaches (subtype categorization to define

68 al data that are amenable to analysis by new informatics approaches alongside conventional statistica

69 in high throughput omics workflows, and new informatics approaches are necessary for processing the

70 Thus, bioimage informatics approaches are needed to rapidly and objecti

71 genomics researchers utilize sequence-based informatics approaches or three-dimensional-structure-ba

72 This availability enables big data informatics approaches to be used to study the spread an

73 demiology, and toxicology communities to use informatics approaches to improve their research workflo

74 ch of the owner, using mass spectrometry and informatics approaches.

75 tions in vaccinology using computational and informatics approaches.

76 The growth of electronic publication and informatics archives makes it possible to harvest vast q

77 s in analytical chemistry, microbiology, and informatics are breaking down the barriers to a fuller a

78 cly available software packages for bioimage informatics are listed for further reference.

79 ontrols, reference materials, statistics and informatics are required for a robust measurement proces

80 individual genes permits the development of informatics-assisted methods for the selection of candid

81 We utilize an unbiased informatics based machine learning approach to classify

82 We used an informatics-based approach to develop a transcriptional

83 To address this issue, we have undertaken an informatics-based approach to understand the genetic and

84 grating data-processing software with larger informatics-based data management platforms.

85 We combine available experimental data with informatics-based immunological predictions to help desi

86 esent study, HITS data were compared with an informatics-based list of putative substrates of the per

87 r hope is to stimulate experimental tests of informatics-based predictions for TGFbeta signaling, as

88 thus impractical in high throughput studies, informatics-based statistical learning approaches can be

89 Comparative informatics between human and mouse data sets identified

90 entific workflows in bioinformatics, medical informatics, biomedical imaging and data analysis, there

91 eating entirely new possibilities for cancer informatics by enhancing data discovery and retrieval.

92 Additional informatics can conceivably be developed to mine and int

93 edicine, European Society of Medical Imaging Informatics, Canadian Association of Radiologists, and A

94 lysis, computational drug discovery, medical informatics, cancer genomics, and systems biology.

95 yside and Fife were identified by the Health Informatics Centre (HIC) and invited to take part in the

96 All data were anonymised according to Health Informatics Centre standard operating procedures.

97 provided by the University of Dundee Health Informatics Centre, who have access to health-related po

98 The increasing omics data present a daunting informatics challenge.

99 s paper provides an overview of the bioimage informatics challenges and approaches in image-based stu

100 types and huge data volume poses formidable informatics challenges for base calling, read alignment

101 One of the major informatics challenges is providing tools that link meta

102 his technique also poses many biological and informatics challenges to extracting meaningful biologic

103 ge data sets that analysis poses significant informatics challenges, particularly for research groups

104 scientific, infrastructural, logistical, and informatics challenges.

105 ddressing similarly complex data science and informatics challenges.

106 tute of Health Research Critical Care Health Informatics Collaborative was studied.

107 Research Centre, as part of the NIHR Health Informatics Collaborative.

108 The Medical Informatics Committee of the American College of Physici

109 A central challenge for the biodiversity informatics community is to provide the means to share a

110 l for biodiversity science, the biodiversity informatics community must address several critical chal

111 e present the recent efforts by the bioimage informatics community to tackle these challenges, and di

112 r has become a critical tool for the pathway informatics community, detecting thousands of errors and

113 ents and practicing radiologists outside the informatics community.

114 One goal of the informatics component of our project has been to generat

115 y dissipation in the memory and other binary informatics components are insignificant compared to the

116 to fundamental RNA-seq molecular biology and informatics concepts.

117 at established the International Arabidopsis Informatics Consortium (IAIC).

118 System (WheatIS) and the International Rice Informatics Consortium (IRIC) to establish Web-based sin

119 benefits include reduced infrastructure and informatics costs in managing and analyzing large sequen

120 lation hosted by the UIC Center for Research Informatics (CRI) at galaxy.cri.uic.edu.

121 es, parallel acquisition of large-scale drug-informatics data provides significant opportunities to i

122 tch up with an avalanche of freely available informatics data.

123 t cardiovascular disease care innovations in informatics, data uses, patient engagement, continuous l

124 ion of clinical approach with a more formal, informatics-derived approach to characterization and a B

125 which can be easily parsed due to accessible informatics-derived image analysis tools, can provide bo

126 with a speculative discussion of what future informatics developments may hold for cognitive neurosci

127 ional setting for teaching in the bio/health informatics disciplines.

128 rt 1 of this review on the basics of imaging informatics discussed the elements that make up a pictur

129 chers unprecedented opportunities for health informatics, disease-risk prediction, actionable clinica

130 Here we review the increasingly large role informatics-driven approaches are playing in such effort

131 Decades of informatics-driven research have relied on expert-design

132 Rapid developments in informatics, emphases on large sample collection for gen

133 comparative questions is an early version of informatics-enabled CER familiar to oncologists.

134 An updated version of informatics-enabled CER relies on EHR-derived structured

135 ChemBank is a public, web-based informatics environment developed through a collaboratio

136 atory networks (GRNs) and thereby provide an informatics environment to study the effects of interven

137 ons on potential solutions based on bioimage informatics, especially automated image computing.

138 allowing biomedical scientists with minimal informatics expertise to remotely call, view, and furthe

139 lp readers, including those without bioimage informatics expertise, understand the capabilities, appr

140 by individuals or groups that lack clinical informatics expertise.

141 erstanding of the mammalian genome thanks to informatics, expression profiling and sequencing of the

142 ll status of available software for bioimage informatics, focusing on open-source options.

143 In the paradigm of materials informatics for accelerated materials discovery, the cho

144 The i2b2 Center (Informatics for Integrating Biology and the Bedside) has

145 fragment mapping based on the Protein-Ligand Informatics force field (PLIff).

146 This paper introduces the protein-ligand informatics "force field", PLIff, which begins to addres

147 The entire biomedical imaging informatics framework consists of cell detection, segmen

148 developed a statistical-thermodynamics-based informatics framework, which allows us to probe for the

149 The cancer Biomedical Informatics Grid (caBIG(R)) Life Science BAM (LS BAM) pr

150 ctor Machine (PUGSVM) is a cancer Biomedical Informatics Grid (caBIG) analytical tool for multiclass

151 l-scale effort, called the cancer Biomedical Informatics Grid (caBIGtrade mark), to develop a federat

152 twork (DDN) is a caBIG(R) (cancer Biomedical Informatics Grid) analytical tool for detecting and visu

153 Here we develop an informatics-guided ab initio approach to accelerate the

154 f metabolite databases, and progress in (bio)informatics has made agnostic approaches more attractive

155 ng-based analyses, other areas of biological informatics have not yet adopted them.

156 Advances in DNA sequencing and informatics have revolutionised biology over the past fo

157 ncluded GeneWeaver, String, and Mouse Genome Informatics identified a total of nine additional candid

158 gnosis (CAD), Computer Applications-General (Informatics), Image Postprocessing, Informatics, Neural

159 of North America and the Society for Imaging Informatics in Medicine conferences (November 2016-June

160 iety of Radiology, RSNA, Society for Imaging Informatics in Medicine, European Society of Medical Ima

161 ter-based image analysis system (Imaging and Informatics in ROP [i-ROP]) was developed using a set of

162 Part 2 will focus on the impact of informatics in the radiology reading room and on recent

163 control the activity of the enhancers using informatics, in vivo occupancy by TFs that regulate cort

164 In summary, this novel web server (cancer.informatics.indiana.edu/mmia) will provide life science

165 The development of biological informatics infrastructure capable of supporting growing

166 it is accompanied by an equal investment in informatics infrastructure.

167 ped, many with clinical decision support and informatics interoperability, but few access patient inf

168 evaluate the impact of incorporating health informatics into the management of SAB via a pharmacist-

169 Informatics is a broad field encompassing artificial int

170 Imaging informatics is a distinct subspecialty of radiology that

171 Biodiversity informatics is an emerging field that applies informatio

172 Computational vaccinology or vaccine informatics is an interdisciplinary field that addresses

173 A major challenge facing biodiversity informatics is integrating data stored in widely distrib

174 Clinical pathway informatics is regarded as an efficient way to solve a s

175 ents in the field and relevant topics (e.g., informatics, laboratory science, emerging topics) to mai

176 We have devised a chemocentric informatics methodology for drug discovery integrating i

177 We survey a broad range of informatics methods and tools that are available to the

178 Further, informatics methods are presented to confidently filter

179 vey emerging computational and translational informatics methods capable of constructing a single sub

180 egration with the other data in Mouse Genome Informatics (MGI) and interconnections with other databa

181 genetic and phenotypic data in Mouse Genome Informatics (MGI) and made readily accessible to many ty

182 GD) is a major component of the Mouse Genome Informatics (MGI) database resource and serves as the pr

183 Integration with the other Mouse Genome Informatics (MGI) databases places the gene expression i

184 are formally represented in the Mouse Genome Informatics (MGI) resource.

185 MGD is a major component of the Mouse Genome Informatics (MGI) resource.

186 through integration with other Mouse Genome Informatics (MGI) resources and interconnections with ma

187 ase and three data types from Mouse Genomics Informatics (MGI).

188 r applications to bioinformatics and medical informatics, namely covariate adjustments.

189 to biologist and therapist to get real time informatics needed to evaluate death process, diseases p

190 tool for AD management program to obtain bio-informatics needed to optimize therapeutics for neurodeg

191 f the challenges in genomics derive from the informatics needed to store and analyze the raw sequenci

192 General (Informatics), Image Postprocessing, Informatics, Neural Networks, Neuro-Oncology, Oncology,

193 Thus, a core question in the informatics of drug design is what type of molecular sim

194 ntent super-resolution nanoscopy and imaging informatics of the nuclear organization of epi-marks.

195 nalytical framework-the Disease Surveillance Informatics Optimization and Simulation (DIOS) framework

196 hardware, expensive apparatus, and advanced informatics or can only be used in single experimental m

197 ed to explore the role of healthcare system, informatics, organizational and practice-related factors

198 A number of informatics packages have been developed for this purpos

199 em, focusing on 4 major domains: science and informatics, patient-clinician partnerships, incentives,

200 ication of NGS-based genetic testing from an informatics perspective.

201 enes, which were processed with an automated informatics pipeline and manually annotated.

202 d as a robust component in a high throughput informatics pipeline for large-scale brain mapping proje

203 e light sheet instrumentation and an imaging informatics pipeline of five steps to achieve mapping of

204 tilizing an in-house assembly and analytical informatics pipeline.

205 ughput whole brain imaging, and an automated informatics pipeline.

206 of 334,652 SNVs that were consistent between informatics pipelines yet inconsistent with haplotype tr

207 also developed and benchmarked optimized PDX informatics pipelines, and these yielded robust assessme

208 mechanism, not currently factored by genomic informatics pipelines, is relevant to diagnosis and prec

209 uestionnaires on atopy were acquired through informatics platform (AllergyCARD).

210 Pathology Image Informatics Platform (PIIP) is an NCI/NIH sponsored proj

211 Using our informatics platform pHinder, we identified a triad of b

212 s the most comprehensive data repository and informatics platform related to the laboratory rat, one

213 rain Institute with access to Brain-CODE, an informatics platform that hosts a multitude of biologica

214 r advanced imaging tools and clinical trials informatics platforms.

215 Understanding informatics principles is important because these princi

216 of time series is beneficial for biomedical informatics problems such including, but not limited to,

217 resource created by the Genetic Resource and Informatics Program at the Oregon National Primate Resea

218 is is a first report, using our MotifModeler informatics program, to simultaneously identify transcri

219 blended Master's degree module for a Health Informatics programme and a fully online distance learni

220 unity effort that combines modern bioimaging informatics, recent leaps in labeling and microscopy, an

221 While mainstream biomedical informatics research focuses on developing more accurate

222 d noncoding RNAs absent from The Arabidopsis Informatics Resource 10 build.

223 vidual investigator's laboratories and major informatics resource centers such as Ensembl, UniProt an

224 vidual investigator's laboratories and major informatics resource centers, such as Ensembl, UniProt a

225 idual investigators and downloads from major informatics resource centers.

226 are driving the development of shared online informatics resources by gaining access to data where it

227 Web 2.0 and advanced informatics resources will be part of physician lifelong

228 on and sustainability of international mouse informatics resources), with a remit to assess the techn

229 Based on the informatics results, we analyzed the respiratory functio

230 Genomics is a sequence-based informatics science and a three-dimensional-structure-ba

231 experimental miRNA researchers, but also for informatics scientists developing the next-generation mi

232 hly curated, community-oriented database and informatics service to researchers focused on the crop p

233 Structural informatics shows that the designed packing motif recurs

234 Although the procedure assumes basic informatics skills, these tools assume little to no back

235 chromatographic data increasingly relies on informatics solutions that attempt to predict an analyte

236 ation studies, there is currently a need for informatics solutions that facilitate the integration of

237 wn vision for future development of bioimage informatics solutions.

238 sciplinary CI team consisting of clinicians, informatics specialists, and analysts spent 6 weeks asse

239 re supporting data sharing, data management, informatics, statistical methodology, and research ethic

240 In recent years, informatics studies have predicted several new ways in w

241 Informatics studies suggest that related catalytic domai

242 LIMITATION: This was a 1-year informatics study conducted at a single hospital subspec

243 to invest significant resources into custom informatics support for genome sequencing projects remai

244 Sipros/ProRata is a versatile informatics system that enables identification and quant

245 computational challenge, requiring powerful informatics systems and bioinformatics expertise.

246 ta may be kept securely under governance and informatics systems that are fit-for-purpose and appropr

247 hat an opportunity exists to employ hospital informatics systems to improve the prescription of antib

248 odology and the development of interoperable informatics systems, which has been recognized by the Na

249 and improve patient safety and quality, and informatics systems.

250 e range of topics in bioinformatics, medical informatics, systems biology and intelligent computing.

251 metabolomics, lipidomics and phenomics with informatics techniques to provide new insights into card

252 in public health toward a focus on including informatics, technologic innovation, molecular epidemiol

253 l modelling, diagnostic, communications, and informatics technologies can identify and report hithert

254 addressed is how human-machine interface and informatics technologies could combine to transform the

255 With current informatics technology and machine learning algorithms,

256 entary and potentially transformative health informatics technology for research and patient care.

257 Advances in image acquisition and informatics technology have led to organism-scale spatio

258 nalysis, the use of social media and medical informatics that will further advance clinical medicine

259 Modern biomedical informatics theory and practice has demonstrated the dis

260 systems (PACS) are a major focus of imaging informatics, there are many other ways in which technolo

261 In addition, the advancement of informatics to allow the intersection of multiple comple

262 These findings were shown by informatics to be relevant to the head morphogenesis of

263 ervention comprising professional education, informatics to facilitate review, and financial incentiv

264 Here, we call for a more formal waste informatics to organize and standardize waste management

265 ecades, chemoinformatics, the application of informatics to solve problems in chemistry, has increasi

266 ssical mechanics simulations, and structural informatics to understand this aspect of ion partitionin

267 After validation, the informatics toolkit was used to populate an exposure rep

268 New informatics tools are needed to model the experimental a

269 ccurred despite a lag in the capabilities of informatics tools available to process the complex data

270 Antibody informatics tools can help improve our understanding of

271 Advanced informatics tools can identify phenotypically relevant d

272 nts Toolkit (CRAVAT) is an evolving suite of informatics tools for mutation interpretation that inclu

273 resources, but there is a critical need for informatics tools in individual laboratories to help man

274 DDAP has advantages compared to previous informatics tools in several aspects: (i) it does not re

275 ir interplay break inversion symmetry, while informatics tools learn from available data to select ca

276 While existing informatics tools provide efficient bulk variant annotat

277 nstrate the need for advanced cancer imaging informatics tools that can help ensure protocol-complian

278 ubstantial efforts have been made to develop informatics tools to alleviate MS data interpretation.

279 Thus, there is a growing demand for informatics tools to analyze FT-MS data that will aid in

280 We used cell-based reporter methods and informatics tools to efficiently screen a large collecti

281 sed functional signatures with complementary informatics tools to examine drug combinations.

282 hput screening (qHTS) approach combined with informatics tools to screen the Tox21 library of 10,000

283 The current generation of these informatics tools was developed for Illumina data, evolv

284 free text concepts identified using clinical informatics tools, disease labels can be assigned with a

285 seeking to ensure that there are appropriate informatics tools, systems and databases available to ma

286 Here, using newly developed informatics tools, we tracked changes in DNA copy number

287 s therefore a central step toward developing informatics tools, which can support the clinician in th

288 pertise and familiarity with a wide range of informatics tools.

289 les, partly due to the large availability of informatics tools.

290 digital image archives by using open-source informatics tools.

291 functionally validated data set to calibrate informatics tools.

292 sis in life sciences, as researchers without informatics training attempt to perform computation-depe

293 NG, AND PARTICIPANTS: The randomized Genetic Informatics Trial (GIFT) of Warfarin to Prevent Deep Vei

294 The randomized clinical Genetic Informatics Trial (GIFT) of Warfarin to Prevent Deep Vei

295 ers) from the Scottish Primary Care Clinical Informatics Unit Research (PCCIU-R) database were descri

296 g of the nature and clinical significance of informatics variability and adopting strategies to reduc

297 ining nanoscopy with epi-mark textural image informatics, we developed a novel approach, termed EDICT

298 MTB is accessed via the Mouse Genome Informatics web site.

299 Shotgun proteomics and informatics were used to identify the LSEC mediator that

300 To construct the optimization informatics workflow, a number of critical components ha