ライフサイエンスコーパス: inhalation

1 ar lavage fluid 8 h after lipopolysaccharide inhalation.

2 n a mouse model of acute Alternaria allergen inhalation.

3 ning parameters did not change after aerosol inhalation.

4 e health outcomes associated with cyanotoxin inhalation.

5 ibution of delivered active components after inhalation.

6 ailed role of CXCR7 in a murine model of LPS inhalation.

7 sols and those produced for drug delivery by inhalation.

8 sibility was determined after bronchodilator inhalation.

9 roduction and mucus secretion after allergen inhalation.

10 e prevalence, where exposure is typically by inhalation.

11 o greater than 90% with once-daily dosing by inhalation.

12 ponsible for respiratory disorders following inhalation.

13 or asthma and provide bronchorelaxation upon inhalation.

14 ticles with tailored particle properties for inhalation.

15 able for targeted delivery to the airways by inhalation.

16 e data set was acquired after bronchodilator inhalation.

17 s the least understood exposure route is via inhalation.

18 oss neurons, but not the latency relative to inhalation.

19 nd air flow paths across the epithelium upon inhalation.

20 ble and concentrated polyplexes suitable for inhalation.

21 thma and may augment the effects of allergen inhalation.

22 ive to changes in response to bronchodilator inhalation (58%) than spirometry (33%).

23 Hypertonic saline inhalation acutely reduced non-cystic fibrosis bronchiec

24 monoxide in a pill." This should enable non-inhalation administration including oral and intravenous

25 one and Nrf2 agonist, for targeted pulmonary inhalation aerosol drug delivery.

26 id state chemical analysis of pharmaceutical inhalation aerosols at the individual particle level has

27 HDM inhalation also increased serum IL-4 and IL-17 levels an

28 nd approved treatment for poisoning by ricin inhalation, although there have been major improvements

29 Following lipopolysaccharide inhalation, alveolar macrophages strongly up-regulate cy

30 antibody fragments that can be delivered by inhalation and are amenable to relatively inexpensive la

31 and perfluorooctyl sulfonate (PFOS) through inhalation and biotransformation of PFAS precursors in a

32 several emerging flame retardants (EFRs) via inhalation and dust ingestion.

33 jected to chronic intermittent ethanol (CIE) inhalation and examined changes in local inhibitory cont

34 early detection of prions in blood following inhalation and has implications for horizontal prion tra

35 The potential for microplastic inhalation and how the source of drinking water may affe

36 d GI tract using XRF microscopy and link the inhalation and ingestion pathways for metal exposure ass

37 no tachycardia/PVCs in conscious SHs, while inhalation and injection of AITC caused similar bradypno

38 d the spontaneously hypertensive (SH) rat to inhalation and intravenous injection of the noxious stim

39 rough near-field exposure routes such as air inhalation and nondietary dust ingestion as well as far-

40 delivery both drugs directly to the lungs by inhalation and tested NLC loaded with drugs in vitro (no

41 dy showed that changes after beta(2) agonist inhalation and the correlation with the lung function pa

42 encountered by respiratory viruses following inhalation and the primary site of respiratory viral rep

43 marijuana in its variety of forms, including inhalation and vaping.

44 % (CI, 96% to 100%), respectively, when only inhalation anthrax cases or higher-quality case reports

45 Following inhalation, Aspergillus conidia deposit in the small air

46 LABA budesonide/formoterol (BUD/F) 200/6 one inhalation b.i.d.

47 halations b.i.d. (n = 31) or BUD/F 200/6 two inhalations b.i.d. (n = 29).

48 ment with either a high dose BDP/F 100/6 two inhalations b.i.d. (n = 31) or BUD/F 200/6 two inhalatio

49 9 control non-users, to determine if chronic inhalation-based exposure to marijuana was associated wi

50 Inhalation-based siRNA delivery designed for efficient,

51 The role of inhalation behaviors as predictors of nicotine uptake wa

52 The derived inhalation bioaccessibility in the PM(10) size fraction

53 When exposed to peanut flour by inhalation, both BALB/c and C57BL/6 mice developed peanu

54 After human inhalation, C. burnetii is engulfed by alveolar macropha

55 Allergen inhalation caused both an early (mean +/- SD, 38.2% +/-

56 s with OA ascertained by a positive specific inhalation challenge (SIC) with NRL gloves and in 25 sym

57 diagnosing OA defined as a positive specific inhalation challenge (SIC).

58 the most accurate investigation is specific inhalation challenge in an experienced centre, this is a

59 ones and also in the cough response to SO(2) inhalation challenge in awake mice.

60 en-driven airway allergic inflammation after inhalation challenge in epicutaneously sensitized mice.

61 t not IL-22, blockade at the time of antigen inhalation challenge inhibited airway inflammation in ep

62 Pharmacological blockade of CysLT2R prior to inhalation challenge of Ptges(-/-) mice with aspirin blo

63 f subjects with OA ascertained by a positive inhalation challenge response to HMW (n = 544) and LMW (

64 r exposure to LMW and HMW agents by specific inhalation challenge test (SIC).

65 chamber followed immediately by an allergen inhalation challenge.

66 of bronchopulmonary C-fibres in response to inhalation challenges of SO(2) (500-1500 p.p.m., 10 brea

67 ologic response to subsequent lysine-aspirin inhalation challenges, as well as increases in levels of

68 mmation in response to repetitive Alternaria inhalation challenges.

69 lfur dioxide (SO2; 5.6 ppm), in a whole-body inhalation chamber.

70 gic airway inflammation following dry powder inhalation combined with a moderate systemic GR-effect,

71 previously demonstrated that carbon dioxide inhalation could induce panic anxiety in a group of rare

72 Thus, microplastic exposure via diet or inhalation could occur, the human health effects of whic

73 itis (EP) in the presence of cigarette smoke inhalation (CSI).

74 Based on our extensive experience in inhalation delivering of drugs by different nanocarriers

75 formulated into a dry powder product for the inhalation delivery of proteins, with no significant lun

76 ention and treatment, especially as portable inhalation devices in high-risk, resource-poor settings.

77 nfusion of acetazolamide with sodium nitrite inhalation did not further increase exhaled NO concentra

78 Human terpene exposure can come from inhalation, diet, smoking, and more recently, using e-ci

79 efficiency for the carrier based dry powder inhalation (DPI).

80 investigate the effects of short-term ozone inhalation during implantation on fetal growth outcomes

81 sis that cigarette smoking-relevant nicotine inhalation during pregnancy impairs cardiovascular funct

82 In addition to neutrophil influx, O3 inhalation elicited the appearance of eosinophils and IL

83 (17)O(2) gas inhalation enabled dynamic measurement of the cerebral m

84 Direct mucosal exposure to HBCD during HDM inhalation enhanced IL-4 or IL-17A production, depending

85 AITC inhalation evoked atropine-sensitive bradycardia in cons

86 Cigarette smoke inhalation exposes the respiratory system to thousands o

87 at the brooches could be used to approximate inhalation exposure and other exposures related to air c

88 In this report, we present a comprehensive inhalation exposure assessment of indoor microenvironmen

89 However, the inhalation exposure assessment points to a minimum risk

90 ll, and CYP2A13/2F1-humanized mice following inhalation exposure at an occupationally relevant dose (

91 oses (0.5-100 mug/mL) corresponding to human inhalation exposure durations at the consumer level of 8

92 resses, and provides first approximation for inhalation exposure during sleep, based on measured emis

93 mechanisms of adverse health effects through inhalation exposure is critical to mitigating its potent

94 ic analysis to show that some children's PCB inhalation exposure may be equal to or higher than their

95 h to surpass the reference concentration for inhalation exposure of 1 mg/m(3) according to the EPA's

96 In this study, we performed inhalation exposure of mice fed normal chow or a high-fa

97 Our studies demonstrated that inhalation exposure of mice fed normal chow to concentra

98 als gained notoriety in the early 2000s when inhalation exposure of the flavoring chemical diacetyl w

99 This presents a plausible inhalation exposure pathway, should microplastics occur

100 biokinetics in rats during Study 1: two-year inhalation exposure to 50 mg/m(3) BaSO(4) NP aerosols, a

101 Inhalation exposure to airborne respirable crystalline s

102 racterizing in vitro pathway-based risks via inhalation exposure to ambient PAHs.

103 Inhalation exposure to nanoparticles from toner-based la

104 Further investigation revealed that inhalation exposure to PM2.5 induced hepatic autophagy i

105 igated the complex effects and mechanisms of inhalation exposure to PM2.5 on hepatic steatosis, a pre

106 Inhalation exposure to the microbial and allergenic cont

107 occurs from handling camping tents and that inhalation exposure will likely occur while inside a ten

108 In relation to inhalation exposure, dust ingestion appears to be the ma

109 exhaled air concentrations resulting from an inhalation exposure.

110 s by high-resolution TEM following 12 months inhalation exposure.

111 This study evaluates infant and adult inhalation exposures and respiratory tract deposited dos

112 s that dietary exposure is comparable to PCB inhalation exposures reported for the same study populat

113 highlight the potentially high occupational inhalation exposures to nanoparticles with complex compo

114 th risks from ED operations due to increased inhalation exposures to PCBs and fine particulate matter

115 nanomaterials (ENMs), little is known about inhalation exposures to these nanoparticles and work pra

116 nerability in the face of acute severe toxic inhalation exposures.

117 omalizumab to regular inhaled corticosteroid inhalation failed to relieve symptoms.

118 matching placebo three times a day via oral inhalation for 2 weeks, followed by a 2 week washout, an

119 when combined with postoperative 50% oxygen inhalation for 3 days, a number comparable to that requi

120 , naive mice were exposed to peanut flour by inhalation for up to 4 weeks.

121 hysicochemical properties, selected drug and inhalation format can greatly influence the pharmacokine

122 To develop an inhalation formulation, the protein complexes were spray

123 l MCs responded differentially to changes in inhalation frequency, whereas sTC responses were more un

124 d activation of MTCs while precisely varying inhalation frequency.

125 Methods: Brain uptake of nicotine following inhalation from E-cigs was directly assessed in 17 E-cig

126 and 8 women), brain uptake of nicotine after inhalation from E-cigs was directly assessed using (11)C

127 ee treatment groups: albuterol (100 mug, two inhalations from a pressurized metered-dose inhaler as n

128 Oxygen inhalation generated lung signal enhancement of 19% +/-

129 significantly in response to bronchodilator inhalation, globally and regionally, and the ventilation

130 e delivery of drugs directly to the lungs by inhalation has a potential to enhance the efficacy of th

131 rs of palytoxin, a highly potent toxin whose inhalation hazard is however unknown.

132 roperties and thus may pose an asbestos-like inhalation hazard.

133 lacenta during normal pregnancy and maternal inhalation hypoxia.

134 ndings challenge the safety of pure nicotine inhalation, i.e., E-cigarettes.

135 cally high levels in the United States, with inhalation (ie, smoking and vaping) being one of the mos

136 ional ventilation response to bronchodilator inhalation in a cohort of patients with asthma.

137 oagulation effects of thermal burn and smoke inhalation in cats.

138 regulation of shelterin complex after silica inhalation in rats, and how this pathway may lead to the

139 Our data suggest that AITC inhalation in SH rats evokes de novo adrenergic reflexes

140 an occupational exposure (e.g., welding fume inhalation) in combination with diet, age, and strain, t

141 osure, plus airway Lipopolysaccharides (LPS) inhalation, in building our COPD mouse model.

142 Repeated HDM inhalation induced a mixed IL-13/IL-17A response and acc

143 Using an acid inhalation-induced lung injury model, we explored the me

144 n B. pseudomallei survival in vivo following inhalation infection and the antibacterial signaling net

145 by PA, MAP, and TSP in the <10 mum fraction (inhalation-ingestion bioaccessibility assay).

146 gender, total body surface area burned, and inhalation injury (hazard ratio, 1.73; 95% CI, 1.18-2.54

147 The 3-variable model with %TBSA, inhalation injury, and von Willebrand factor could be us

148 idate models, a 3-variable model with %TBSA, inhalation injury, and von Willebrand factor-A2 had comp

149 of 113 patients with isolated burn injury or inhalation injury.

150 ore TBSA burn similar in age, TBSA burn, and inhalation injury.

151 cal studies of patients with burns and smoke inhalation injury.

152 ptake has been shown to be comparable to the inhalation intake for compounds with certain chemical pr

153 surviving in the external environment before inhalation into a new potential host-steps influenced by

154 Noninvasive aerosol inhalation is an established method of drug delivery to

155 Maternal smoking with obligatory nicotine inhalation is associated with preterm delivery, low birt

156 estimates increase to 74000 and 121000 when inhalation is considered.

157 location, and health-related impacts of AgNP inhalation is limited.

158 The conventional method of Xe delivery by inhalation is not feasible on a chronic basis.

159 Particle deposition in the lung during inhalation is of interest to a wide range of biomedical

160 fficacy and safety of liposomal amikacin for inhalation (LAI) in treatment-refractory pulmonary nontu

161 e to each other (synchrony) and the onset of inhalation (latency).

162 uorescence with only a slight enhancement of inhalation-linked responses to odorant.

163 and standard surgical defect creation under inhalation/local anesthesia.

164 onic cigarette-type technology to facilitate inhalation, male Wistar rats were exposed to vaporized m

165 HDM inhalation markedly increased airway goblet cell numbers

166 imple control measures to reduce particulate inhalation might reduce the incidence of invasive bacter

167 ame sequence type was analyzed using a mouse inhalation model of cryptococcosis.

168 ortality rates, demonstrating that the mouse inhalation model recapitulates human infection.

169 ng inflammatory injury in an aerosolized LPS inhalation mouse model of acute lung injury (ALI).

170 This clinically relevant nicotine aerosol inhalation (NAI) induced transient reduction and irregul

171 , including subcutaneous, transdermal, oral, inhalation, nasal and buccal routes.

172 Effects of inhalation of 5% or 10% CO(2) on arteriolar diameter wer

173 randomized across five sites to twice-daily inhalation of 6% HS (n = 21) or 0.9% IS (n = 21) for 52

174 ums of the inspiratory flow before and after inhalation of a beta(2) stimulant were analyzed.

175 sets of baseline images were acquired before inhalation of a bronchodilating agent (salbutamol 400 mu

176 igate the airway effects in humans caused by inhalation of a known concentration of a single phthalat

177 ath-hold (19)F gas wash-in MR imaging during inhalation of a normoxic fluorinated gas mixture (perflu

178 Results: After inhalation of a single puff of E-cig vapor, brain nicoti

179 tis (HP) is a complex syndrome caused by the inhalation of a variety of antigens in susceptible and s

180 of endothelial function in nonsmokers after inhalation of aerosol from nicotine-free e-cigarettes.

181 onic tularemia in humans typically occurs by inhalation of aerosolized bacteria, the rat model has re

182 E Humans acquire hantavirus infection by the inhalation of aerosolized excreta of infected rodent hos

183 We show that inhalation of aerosolized H5N1 influenza virus in cynomo

184 These data establish inhalation of aerosolized virus as a critical source of

185 In allergic asthma, inhalation of airborne allergens such as the house dust

186 llergic immune responses were induced by the inhalation of antigen during IL-1alpha release and iBALT

187 inhaled antigen alone but were augmented by inhalation of antigen together with HDE.

188 However, whether the inhalation of bacteria triggers ASL secretion and whethe

189 is a concern over health risks presented by inhalation of carbon nanotube (CNT) aerosol in workplace

190 -negative bacterium transmitted to humans by inhalation of contaminated aerosols.

191 eptor-mediated ASL secretory response to the inhalation of cystic fibrosis relevant bacteria.

192 In the mouse olfactory bulb, inhalation of different odors leads to changes in the se

193 and the pulmonary health effects induced by inhalation of DMSe-derived SOA remain largely unknown.

194 We find that inhalation of dry air impairs mucociliary clearance, inn

195 unotoxicological outcomes following repeated inhalation of dry Aspergillus fumigatus spores aerosoliz

196 velocity.Conclusions: Our findings show that inhalation of e-cig vapor causes airway mucociliary dysf

197 Epidemiological studies associate inhalation of fine-sized particulate matter (PM2.5) duri

198 Inhalation of Francisella tularensis causes pneumonic tu

199 Repeated inhalation of fungal aerosols resulted in significant pu

200 entially hazardous to the airways because of inhalation of house dust.

201 .2 ng g(-1) of luciferase protein 24 h after inhalation of hPBAE polyplexes.

202 Measurements and Main Results: Inhalation of HS and IS was generally well tolerated by

203 Finally, inhalation of hydrogen gas in adolescence significantly

204 The results showed that repeated inhalation of hydrogen-oxygen mixed gas [67%:33% (V/V)]

205 ELISA analyses showed that inhalation of hydrogen-oxygen mixed gas blocked CMS-indu

206 ienced anaphylactic reactions just after the inhalation of Inavir (Laninamivir Octanoate Hydrate) to

207 rtition coefficient K(OW) < 10(11)), whereas inhalation of indoor air dominates human exposure to vol

208 nd can transmit cryptococcosis to humans via inhalation of inoculated bird excreta.

209 The reaction can be mimicked by inhalation of mannitol, but it has paradoxically previou

210 Whether inhalation of metabolites of environmental bacteria cont

211 TB) is a significant human disease caused by inhalation of Mycobacterium tuberculosis.

212 Inhalation of noxious irritants/pollutants activates air

213 izing radiation from natural sources through inhalation of particles.

214 Inhalation of phosphatidylserine coated liposome loaded

215 ROS are introduced to the body via inhalation of PM with these species present on and/or wi

216 d through direct or airborne transmission by inhalation of respiratory droplets.

217 neal injection of propofol and maintained by inhalation of sevoflurane for 1 hr.

218 Inhalation of silica particles can induce inflammatory l

219 In addition, inhalation of SO(2) consistently evoked coughs in awake

220 Brief inhalation of SO(2) of concentration >500 p.p.m. trigger

221 Inhalation of SO(2) reproducibly induced a pronounced an

222 In mice inhalation of SplD without adjuvant induced lung inflamm

223 Inhalation of sulfur dioxide (SO(2) ) triggers coughs an

224 Inhalation of the ambient air pollutant ozone causes lun

225 We hypothesized that inhalation of the anti-viral cytokine, interferon (IFN)-

226 Inhalation of the bacterium Yersinia pestis results in p

227 g dynamic (19)F gas washout MR imaging after inhalation of the gas mixture was finished for a total o

228 ly inhibited respiratory responses evoked by inhalation of the nociceptor stimulant capsaicin.

229 ring ambient air breathing (Amb) and a 6 min inhalation of the vasodilator nitric oxide (iNO; 40 ppm

230 Inhalation of these contaminants significantly suppresse

231 tion to a civilian or military population by inhalation of toxic bioaerosol.

232 his study was to assess the effect of silica inhalation on telomere length and the regulation of RTEL

233 ions twice daily plus tiotropium 2.5 mug two inhalations once daily.

234 can use information occurring <100 ms after inhalation onset to identify odors.

235 Dust inhalation or exposure to high temperatures promoted pro

236 Inhalation or ingestion of ricin may even lead to death.

237 on insect allergy induced via stings, bites, inhalation or ingestion, and compare reactions in compan

238 In particular, WF inhalation over an extended period carries an increased

239 Airway collapse can occur when the forces of inhalation overpower the strength of the nasal lining fl

240 Flow Volume after 240s of hypertonic saline inhalation; p = 4.81*10(-4)) and CD14 rs2569190 was asso

241 sphate and iron amendments via ingestion and inhalation pathways using in vitro and in vivo assays, i

242 raction) were observed via the ingestion and inhalation pathways, respectively.

243 , which may not accurately reflect realistic inhalation patterns, since atmospheric aerosols are most

244 After a 2-week run-in period receiving one inhalation per day via single-dose dry-powder inhaler of

245 of an albuterol rescue inhaler (2.8 and 3.0 inhalations per week, respectively; P=0.69), unscheduled

246 f CVT-301, a self-administered levodopa oral inhalation powder, for the treatment of patients with Pa

247 delivery of lipid-based nanotherapeutics by inhalation presents an advantageous alternative to oral

248 For lung-related indications, inhalation provides localized delivery in order to enhan

249 ferences in physical human attributes (e.g., inhalation rate).

250 We found that OT inhalation selectively reduced a selection bias against

251 Additionally, CO gas inhalation significantly alleviated APAP-induced liver d

252 Using an inhalation simulator we measured peak inhaled flow (PIF)

253 blets, and chloride in soy sauces and saline inhalation solutions was performed as examples of the ap

254 In summary, this model provides insight into inhalation strategies for targeted drug delivery.

255 el enables fast computation of how different inhalation strategies, called flow policies, determine t

256 Few in vivo inhalation studies have explored the toxicity of environ

257 Amikacin liposome inhalation suspension is recommended for treatment-refra

258 y 12 h for 10 days via the same synchronised inhalation system, and given alongside standard-of-care

259 In a macaque model of inhalation TB, suppression of IDO activity reduced bacte

260 er, extra equipment is needed to perform gas inhalation techniques, and this equipment is not availab

261 from reduced repeatability compared with gas inhalation techniques; however, extra equipment is neede

262 osure, nose-only CS exposure, and airway LPS inhalation testing.

263 appropriate, and in selected cases specific inhalation tests.

264 Protonated nicotine is less aversive upon inhalation than free-base nicotine, and many ECIG manufa

265 ion and a greater response to bronchodilator inhalation than the proximal lung.

266 nical model of opioid self-administration by inhalation that does not require surgery and reliably pr

267 Before beta(2) agonist inhalation, the area under the entire curve (A(T)) and 9

268 ations are incompletely prevented by maximal inhalation therapy in patients with severe chronic obstr

269 l treatment proved to be beneficial, as were inhalation therapy, chest physiotherapy, and exercise.

270 oplets and aerosol particles, thus posing an inhalation threat even at considerable distance.

271 g of budesonide and 6 mug of formoterol, one inhalation through a Turbuhaler as needed) (budesonide-f

272 (albuterol group); budesonide (200 mug, one inhalation through a Turbuhaler twice daily) plus as-nee

273 and stimulate the olfactory epithelium upon inhalation through the nares (orthonasal olfaction).

274 k and 19-month-old male rats were exposed by inhalation to 10 mg/m(3) of TiO2 nano-aerosol (6 hrs/day

275 ive B6C3F1/N mice were exposed via nose-only inhalation to A. fumigatus viable conidia, heat-inactiva

276 Thus, we show oxygen inhalation to be a simple and promising approach to succ

277 Here we use lipopolysaccharide inhalation to induce acute inflammation in healthy volun

278 Male Fisher 344 rats were exposed by inhalation to Min-U-Sil 5 silica for 3, 6, or 12 wk at a

279 Coupling CO2 inhalation to retrieval increased activation of amygdala

280 ecretome (LSC-Sec) and exosomes (LSC-Exo) by inhalation to treat different models of lung injury and

281 We showed that an inhalation treatment of secretome and exosome exhibited

282 -label BDP/FF (200 mug BDP and 6 mug FF) two inhalations twice daily plus tiotropium 2.5 mug two inha

283 ) or BDP/FF (200 BDP and 6 mug FF), both two inhalations twice daily, or open-label BDP/FF (200 mug B

284 G) or BDP/FF (100 mug BDP and 6 mug FF), two inhalations twice daily.

285 e burn and 48 breaths of cooled cotton smoke inhalation under deep anesthesia and analgesia.

286 es (i.e. reference concentrations [RfCs] and inhalation unit risks [IURs]) available from the USEPA n

287 in a dorso-ventral (D-V) sequence upon odor inhalation, unlike the anterio-posterior (A-P) activity

288 ction of cross-sectional area with simulated inhalation was 87.74% in the control group, 82.76% (IHCC

289 lung sound parameters after beta(2) agonist inhalation was clearer at an inspiratory flow around 1.0

290 ation increase in response to bronchodilator inhalation was greater in the peripheral lung than in th

291 The calculated exposure due to air inhalation was substantially lower when the stationary a

292 volume resuscitation, and salbutamol sulfate inhalation, which resulted in an improvement of the symp

293 Conclusions: Preventive inhalation with HS initiated in the first months of life

294 sibility, safety, and efficacy of preventive inhalation with hypertonic saline (HS) compared with iso

295 iratory Flow after 240s of hypertonic saline inhalation with respect to the age- and ancestry-matched

296 ques.Methods: Sixteen NHPs were infected via inhalation with ~10 cfu of Mtb CDC1551, after which asym

297 logy is also affected by e-cigarette aerosol inhalation, with increased airway reactivity, airway obs

298 BALB/c mice were exposed to peanut flour by inhalation without any exogenous adjuvants.

299 Early after inhalation, Yersinia pestis replicates to high numbers i

300 PCB inhalation yielded mug/g E(209) PCB levels in tissues.