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1 pendent of its cyclin-dependent kinase (CDK) inhibitory action.
2 is widely thought to be essential for their inhibitory action.
3 nd (viii) dominant negative PP2A blocks cAMP-inhibitory action.
4 1) activation by specific siRNAs blocked OGF inhibitory action.
5 e association of golli was essential for its inhibitory action.
6 nd define the mechanism responsible for this inhibitory action.
7 yl may be beneficial for increased TNF-alpha inhibitory action.
8 owed us to probe novel aspects of indolmycin inhibitory action.
9 cellular glycine concentrations can exert an inhibitory action.
10 Co-application of NT and AID peptide negated inhibitory actions.
11 tivation also require PKA activity for their inhibitory actions.
12 wth is not simply the opposite of its growth inhibitory actions.
13 etylcholine agonist muscarine, evoked direct inhibitory actions.
14 of action selection rely on these pathways' inhibitory actions.
15 BA are complex involving both excitatory and inhibitory actions.
16 ioid receptor antagonists prevented morphine inhibitory actions.
17 derations its anti-inflammatory and thrombin-inhibitory actions, a bioavailable form of quercetin, li
20 do)benzenesulfonamides, showed low nanomolar inhibitory action against hCA II, being less effective a
21 (Rv1284, Rv3273, and Rv3588c), whereas their inhibitory action against hCA III, IV, VA, VB, VI, VII,
23 ing click chemistry and showed low nanomolar inhibitory action against the tumor-associated isoforms
24 report that papaverine, a vasodilator, shows inhibitory action against various strains of influenza v
25 ther cell type is sufficient to overcome the inhibitory action and promote differentiation and myelin
26 These effects are independent of its COX-2 inhibitory actions and may explain the differential risk
27 t degradation of s80(HER4) limits its growth-inhibitory action, and stabilization of s80(HER4) enhanc
28 identify a novel P2X7 variant with apoptosis-inhibitory actions, and demonstrate a distinct regulator
31 7SK-binding motif was essential for HEXIM1's inhibitory action, as the HEXIM1 mutants with this motif
32 MDA receptor channels but show that its main inhibitory action at pharmaceutically relevant concentra
34 These peptides are thought to exert their inhibitory action by disrupting the proper assembly of P
36 ns, it is now clear that Imatinib exerts its inhibitory action by stabilizing the inactive non ATP-bi
37 ragment was capable of selective competitive inhibitory action, disrupting endogenous F-actin-Syntaxi
38 te that A(2A) receptor activation has strong inhibitory actions during early developmental, as well a
39 , as well as a molecular explanation for its inhibitory action, emphasizing the oxidative metabolism
40 At the cellular level, we found that the inhibitory action exerted by KYNA in the PFC occurred pr
42 and PDK1, are not the target(s) of the cAMP inhibitory action; (ii) constitutively active Akt and ca
44 gated GABAergic activity and observed mainly inhibitory action in SCN neurons of mice exposed to a sh
48 ta suggest that BTLA and PD-1 exert distinct inhibitory actions in vivo, with the BTLA/herpesvirus en
52 its regulatory gamma-subunits (Pgamma) whose inhibitory action is released upon binding to the G-prot
54 ocytes, indicating that at least part of its inhibitory action is unrelated to its antiplatelet prope
57 ments highlight the importance of the potent inhibitory action mediated by parvalbumin cells in the h
60 tions confirm the proposed mechanism for the inhibitory action of 2-guanidinobenzimidazole (2GBI) der
62 ty evoked by 1-100 nm Ang II and blocked the inhibitory action of [Ca(2+)](i) on TRPC6 channel activi
63 m of light activation that initiates protein inhibitory action of a biologically inert Co(III) Schiff
64 gistic effect with paclitaxel against growth-inhibitory action of a patient-derived pancreatic adenoc
65 ligand exchange reaction is proposed for the inhibitory action of a tight-binding inhibitor possessin
66 Ca2+ via nAChRs, revealing that the apparent inhibitory action of Abeta1-42 was the result of an occl
67 us-mediated Fstl3 overexpression blocked the inhibitory action of activin A on hypertrophy and Smad2
68 GABAergic mechanisms may be involved in this inhibitory action of adenosine, via their A(2A) receptor
71 te the molecular mechanism(s) underlying the inhibitory action of AMX on the release of FGF-1, using
72 balance between estrogen stimulation and the inhibitory action of androgens on breast tissue prolifer
75 s), which counterbalance the nearly constant inhibitory action of ATP on the K(+) inwardly rectifying
78 lengths below 488 nm rapidly inactivates the inhibitory action of blebbistatin using the in vitro mot
82 chromatin is restricted to G1 phase through inhibitory action of Cdk1/2 kinases in other phases of t
83 endrocytes, contributes to the axonal growth inhibitory action of central myelin in growth cone colla
85 for the observed high affinity and enhanced inhibitory action of CIP when compared to either p25 or
86 h increasing CLE3 mRNA levels; however, this inhibitory action of CLE3 was abrogated in the clv1 muta
87 s of HO-1 activity may be attributable to an inhibitory action of CO on cardiac L-type Ca2+ channels.
88 -molecule approaches require blockade of the inhibitory action of cocaine on a diverse array of monoa
89 oliferation and migration correlated with an inhibitory action of cortistatin on the neointimal forma
92 uculline and picrotoxin, suggesting that the inhibitory action of D2 receptors on NMDA-induced respon
96 ct is intriguing in that it does not require inhibitory action of either presynaptic muscarinic recep
97 n adequately addressed is whether the direct inhibitory action of erlotinib on the HER2 kinase might
100 ation serves a role in removing the inherent inhibitory action of flavonoids on an MTI signaling bran
101 restingly, the expression of aP2 escapes the inhibitory action of FoxC2 under conditions that promote
104 repetitive postsynaptic spiking reduces the inhibitory action of GABA through a Ca2+-dependent downr
105 rine cells, and picrotoxin, which blocks the inhibitory action of GABA, only slightly reduced the sur
106 ibition, which has a general implication for inhibitory action of general anesthetics on pLGICs.
108 er, it remains to be determined whether this inhibitory action of GH is due to direct regulation of h
109 prostate shrinkage is induced by the direct inhibitory action of GHRH and of LHRH antagonists exerte
110 we provide evidence for the existence of an inhibitory action of Gi3 on Gs that is under the control
111 signal transduction pathway that conveys the inhibitory action of GnIH in GnRH neurons by using the G
112 odulators strongly demonstrated the specific inhibitory action of GnIH on the adenylate cyclase/cAMP/
117 and experimental approach, we found that the inhibitory action of I(h) was caused by its interaction
118 acid (15(S)-HETE) production, indicating an inhibitory action of I3MO on 12/15-LO and consequently o
119 hanism of hIAPP amyloid fiber formation, the inhibitory action of IAPP variants, and the competition
120 that differ in their ability to support the inhibitory action of IFN-alpha at early steps of the HIV
129 metamorphosis on a normal schedule, and the inhibitory action of juvenile hormone on this checkpoint
132 ectly show the predicted dual fast- and slow-inhibitory action of LNs, which was predicted to be key
140 down in POSH function were refractory to the inhibitory action of Nogo66, indicating that a POSH-depe
141 rolytic conformations able to antagonize the inhibitory action of nucleotide binding at the Kir6.2 po
142 reveal that the target of cell proliferative inhibitory action of OGF in human HNSCC is a cyclin-depe
144 that phosphorylation by Src impairs the Cdk2 inhibitory action of p27 and reduces its steady-state bi
151 conditions when most GABAA Rs were open, an inhibitory action of R-mTFD-MPPB was revealed that had a
153 a T cell function is directly related to the inhibitory action of rapamycin on mammalian target of ra
154 nregulation of Bcl-xL was caused by the mTOR inhibitory action of rapamycin, which prevented cap-depe
160 stabilized by S-S bonds is required for the inhibitory action of S1b on prolactin-induced LF-mediate
163 This particular conformation explains the inhibitory action of sordarin and suggests that eEF2 is
165 eous mucin accumulation, consistent with the inhibitory action of Syt2 at resting cytoplasmic Ca(2+)
168 berates their protein kinase domain from the inhibitory action of the amino-terminal photosensory por
172 Both MRN and SOSS1 also act to mitigate the inhibitory action of the Ku70/80 heterodimer on Exo1 act
174 ein (BBX19), as a molecular link between the inhibitory action of the phytohormone abscisic acid (ABA
178 oledronic acid (ZOL) in order to enhance the inhibitory action of this miRNA on its canonical targets
186 own to have a role in the development of the inhibitory actions of amine transmitters, whereas KCC3 a
188 finding has significant implications for the inhibitory actions of annexin A1 on exocytosis in other
189 ivo, as exemplified by the weak and/or short inhibitory actions of antagonists JV-1-65 and MZ-J-7-72
192 of CIS-R107K for blocking the GHR signaling inhibitory actions of CIS, but not those of other SOCS/C
193 ected COLO-357 cells and enhanced the growth inhibitory actions of cis-diamminedichloroplatinum(II) (
195 kinase (ERK) pathways mediated the sustained inhibitory actions of endogenous opioids and DOPr agonis
197 nel activity, thereby demonstrating that the inhibitory actions of ESCAs reported here are unlikely t
201 could contribute towards the stimulatory and inhibitory actions of FFAs on pancreatic beta-cell funct
207 FP, vGluT2-GFP and GAD67-GFP mice, we report inhibitory actions of GnIH/RFRP-3 on kisspeptin-activate
208 ivator CREB-binding protein/p300 reduced the inhibitory actions of IFN-gamma on the Abca1 promoter, s
209 show that the apoptosis-promoting and growth-inhibitory actions of IGFBP-3 are completely abrogated i
212 y RLR signaling platforms controlled through inhibitory actions of LGP2 binding to MAVS wherein LGP2
215 ase property of the MIF molecule, mimics the inhibitory actions of MIF on Ang II-stimulated neuronal
219 LR-MSCs also demonstrated resistance to the inhibitory actions of PGE2 in association with a reducti
220 on system, and the steady-state kinetics and inhibitory actions of phenothiazines were characterized.
221 tion was used to evoke dopamine release, and inhibitory actions of quinpirole on this release were ex
226 ioral adaptation to both the stimulatory and inhibitory actions of the neurotransmitter, indicating t
227 t stress, while CRF(2) receptors mediate the inhibitory actions of these peptides on gastric transit.
229 ts with transfected cells confirmed that the inhibitory actions of thrombin and Rho kinase on P-selec
232 gly, ectopic expression of IRF9 reverses the inhibitory actions of TSA, suggesting that IRF9 function
234 arguing against the possibility that the PKC inhibitory actions of UCN-01 are responsible for synergi
238 charges suggesting dual, both excitatory and inhibitory, actions of GABA in the immature hippocampal
240 cytes might be the combination of its direct inhibitory action on astrocyte MMP2 expression and the s
241 on with the plasma membrane and reversed its inhibitory action on Ca2+ influx, indicating that membra
242 These results suggest that ethanol via the inhibitory action on D2S receptor activity suppresses Gi
243 whose phosphorylation by mTORC1 reverses its inhibitory action on eIF4E, resulting in the promotion o
245 , 3b and 3f (IC50 approximately 84 nM), lack inhibitory action on ENPP6 and ENPP7 but possess weak an
250 ct of fingolimod in vivo may result from its inhibitory action on key astrocyte activation steps.
252 onal receptor complex that mediates myelin's inhibitory action on nerve fiber regeneration has at las
254 t suppression of NF-kappaB depended on HGF's inhibitory action on NF-kappaB and IkappaB phosphorylati
257 minescence assay was employed to study their inhibitory action on protein synthesis, which identified
261 ductance of the neurons, consistent with its inhibitory action on spike rate, whereas serotonin decre
263 y demonstrating that PACAP exerts a powerful inhibitory action on the induction, growth or survival o
265 atin A, an HDAC inhibitor, prevents IFNgamma inhibitory action on TNFalpha-induced gene expression.
267 ata suggest that catecholamines evoke strong inhibitory actions on hypocretin neurons and suggest neg
268 well as the course of the disease because of inhibitory actions on Kv and ASIC channels, respectively
270 phai1, localization to dendritic spines, and inhibitory actions on LTP induction, while variant RQ ex
271 t suppresses the gastric mill rhythm via its inhibitory actions on MCN1 and CPN2, to inhibit the GPR-
272 ults indicate that rapamycin exerts variable inhibitory actions on mTOR signaling functions and sugge
273 is agent does not have additional downstream inhibitory actions on this activated NF-kappaB subunit.
278 a marked (although not complete) decrease in inhibitory action, suggesting a role of Mad2 in MCC for
280 ivation could be caused by the removal of an inhibitory action that CFs exert on the intrinsic pacema
281 ides a mechanism for switching on or off the inhibitory action that Gbetagamma proteins exert on TRPM
282 explains several effects associated with its inhibitory action: the negative shift in heme c(n) midpo
283 e same binding region; rather, it exerts its inhibitory action through an allosteric mechanism, preve
285 ctive inhibitor rofecoxib, owe part of their inhibitory actions to effects on oxidation state of cycl
286 the smaller fragments and demonstrate their inhibitory action toward the Na(+)-K(+)-2Cl(-) cotranspo
287 n IL-33 activated signaling pathways in such inhibitory actions using RNA interference-mediated knock
288 gon action at the GluR, while having minimal inhibitory action versus glucagon or GLP-1 at the GLP-1R
289 9 and dominant negative Epac 279E block cAMP-inhibitory action; (vi) Epac associates in a complex wit
292 ts were seen in 32D cells arguing the growth inhibitory action was not because of the blockade of aut
293 de shift and GABA switch, from excitatory to inhibitory action, was accelerated by REST inhibition an
295 hereas resolvin E1 and 10,17S-docosatriene's inhibitory actions were maximal at 12 h (30-80% inhibiti
296 ta revealed the molecular basis of this dual inhibitory action, which, in our opinion, will aid in th
297 CC neurons, and examined the effects of this inhibitory action with the attention-based five-choice s
298 creasing carbonic anhydrase (CA, EC 4.2.1.1) inhibitory action with the increase of the number of sul
299 esensitization is an unexplored mechanism of inhibitory action with the potential to endow drugs with
300 nstituent possessing potent aldose reductase inhibitory action, with an IC50 value of 3.8mug/ml.