ライフサイエンスコーパス: inhibitory synaptic transmission

1 -1beta, IL-6, and TNFalpha on excitatory and inhibitory synaptic transmission.

2 atory synaptic transmission or by decreasing inhibitory synaptic transmission.

3 re generally known to suppress excitatory or inhibitory synaptic transmission.

4 s in seizure control likely through enhanced inhibitory synaptic transmission.

5 cally produces a long-lasting enhancement of inhibitory synaptic transmission.

6 t pulses were used to induce modification of inhibitory synaptic transmission.

7 butyric acidergic synapses and important for inhibitory synaptic transmission.

8 us systems, where they mediate rapid, mostly inhibitory synaptic transmission.

9 piking, as well as control of excitatory and inhibitory synaptic transmission.

10 eover, their occurrence and timing relied on inhibitory synaptic transmission.

11 tive splicing of a host of genes involved in inhibitory synaptic transmission.

12 aptic sites to alter GABAA receptor-mediated inhibitory synaptic transmission.

13 monstrate an absolute requirement for phasic inhibitory synaptic transmission.

14 tic sites to alter GABA(A) receptor-mediated inhibitory synaptic transmission.

15 cts are generally viewed in terms of altered inhibitory synaptic transmission.

16 uced after dark rearing and also by blocking inhibitory synaptic transmission.

17 antagonists to block all fast excitatory and inhibitory synaptic transmission.

18 brain resulted in postsynaptic impairment of inhibitory synaptic transmission.

19 ell-autonomous changes in excitatory but not inhibitory synaptic transmission.

20 eased action potential firing, and decreased inhibitory synaptic transmission.

21 ry and sufficient for Neurexin-3 function in inhibitory synaptic transmission.

22 cal conditions associated with dysfunctional inhibitory synaptic transmission.

23 d by altered balance of local excitatory and inhibitory synaptic transmission.

24 velopment by fine-tuning both excitatory and inhibitory synaptic transmission.

25 ard enabling the study of diseases affecting inhibitory synaptic transmission.

26 oteins, play a key role in the modulation of inhibitory synaptic transmission.

27 of epilepsy, probably due to impairments in inhibitory synaptic transmission.

28 that mice lacking IgSF21 exhibit deficits in inhibitory synaptic transmission.

29 but dispensable for both AMPAR-mediated and inhibitory synaptic transmission.

30 leads to increased excitatory and decreased inhibitory synaptic transmission.

31 e receptors (GlyRs), which both mediate fast inhibitory synaptic transmission.

32 thereby affect the polarity and efficacy of inhibitory synaptic transmission.

33 ontrast PGE2 affected neither excitatory nor inhibitory synaptic transmission.

34 citatory synapses produces minimal change in inhibitory synaptic transmission.

35 ns and is required for normal excitatory and inhibitory synaptic transmission.

36 glia did not detectably impair excitatory or inhibitory synaptic transmission.

37 HDAC2 KD reduced, whereas HDAC2 OE enhanced, inhibitory synaptic transmission.

38 neurons, leading to significant reduction of inhibitory synaptic transmission.

39 e recycling which impaired the efficiency of inhibitory synaptic transmission.

40 GABA(A) receptors mediate fast inhibitory synaptic transmission.

41 that ClC-2 reduces spiking independently of inhibitory synaptic transmission.

42 input patterns in the presence or absence of inhibitory synaptic transmission.

43 ion and major defects in excitatory, but not inhibitory, synaptic transmission.

44 Aging generally induces selective loss of inhibitory synaptic transmission along the entire audito

45 ) subunits underlies the variability of fast inhibitory synaptic transmission; alteration of specific

46 d that thyroid hormone alters excitatory and inhibitory synaptic transmission, an effect that require

47 stnatal day 7 display a lasting reduction in inhibitory synaptic transmission, an increase in excitat

48 prived region characterized by a decrease in inhibitory synaptic transmission and a normal hearing re

49 tus alter the balance between excitatory and inhibitory synaptic transmission and associated synaptic

50 erved, critical roles in both excitatory and inhibitory synaptic transmission and can be activated by

51 clamp recordings revealed that it tones down inhibitory synaptic transmission and causes increased ex

52 ate whether and how resveratrol alters basal inhibitory synaptic transmission and cocaine-induced inh

53 the VTA shifts the balance of excitatory and inhibitory synaptic transmission and decreases dopamine

54 This work extends our understanding of inhibitory synaptic transmission and demonstrates the po

55 Strikingly, inhibitory synaptic transmission and GABAergic cells wer

56 ic acid (GABA) type A receptors mediate fast inhibitory synaptic transmission and have been implicate

57 PARs, resulting in a homeostatic decrease in inhibitory synaptic transmission and increased intrinsic

58 t prior predator odor stress exposure blunts inhibitory synaptic transmission and increases synaptic

59 by rapid GABA transients present during fast inhibitory synaptic transmission and is critical to unde

60 naptic densities of neurons, but its role in inhibitory synaptic transmission and plasticity is unkno

61 dance behavior, and demonstrated that intact inhibitory synaptic transmission and proper E/I balance

62 recordings uncovered enhanced excitatory and inhibitory synaptic transmission and reduced firing rate

63 These changes are associated with enhanced inhibitory synaptic transmission and reduced intrinsic n

64 ing evidence indicates that GABA acts beyond inhibitory synaptic transmission and regulates the devel

65 lex, reversed the changes in translation and inhibitory synaptic transmission and rescued the synapti

66 synapse numbers, enhances excitatory but not inhibitory synaptic transmission, and augments NMDAR-med

67 pregulated Na(v)1.1 in PV neurons, increased inhibitory synaptic transmission, and decreased seizures

68 innervation by basket interneurons, enhanced inhibitory synaptic transmission, and earlier onset of o

69 ribute to the balance between excitatory and inhibitory synaptic transmission, and electrical activit

70 did not significantly enhance GABAA-mediated inhibitory synaptic transmission, and GABA receptor anta

71 accompanied by alterations in excitatory and inhibitory synaptic transmission, and intrinsic excitabi

72 accompanied by alterations in excitatory and inhibitory synaptic transmission, and intrinsic excitabi

73 In the CeA, membrane properties, inhibitory synaptic transmission, and responses to CRF b

74 dopamine signaling-dependent potentiation of inhibitory synaptic transmission, and that reduction of

75 (SynII) gene deletion produces a deficit in inhibitory synaptic transmission, and this defect is tho

76 e mechanisms of depression of excitatory and inhibitory synaptic transmission appear to be different.

77 ity-dependent bidirectional modifications of inhibitory synaptic transmission are attributable to bid

78 d this idea by measuring changes to cortical inhibitory synaptic transmission as adult gerbils progre

79 We also find alterations in inhibitory synaptic transmission as miniature IPSC (mIPS

80 caused analgesia and reversed alterations of inhibitory synaptic transmission associated with chronic

81 TPMPA reduced inhibitory synaptic transmission at interneurone-Purkinj

82 out how endogenous NO affects excitatory and inhibitory synaptic transmission at the spinal level.

83 Indeed, the differences in inhibitory synaptic transmission between Fmr1 KO and wil

84 on was still dependent, at least in part, on inhibitory synaptic transmission, but spatiotemporal asp

85 erneurones could contribute to depression of inhibitory synaptic transmission by activation of GABAB

86 acitance recordings to unravel mechanisms of inhibitory synaptic transmission by AIIs.

87 neuronal Cl(-), which is essential for fast inhibitory synaptic transmission by GABA and glycine in

88 We found no increase in spontaneous inhibitory synaptic transmission by hCSF, indicating a d

89 trocytes modulate spontaneous excitatory and inhibitory synaptic transmission by increasing the proba

90 n (MLI)-PC pairs, we investigated changes in inhibitory synaptic transmission caused by dystrophin de

91 de evidence that resveratrol modulates basal inhibitory synaptic transmission, cocaine-induced synapt

92 inhibitory synapses, together with enhanced inhibitory synaptic transmission due to reduced GABA(A)R

93 revealed that the balance of excitatory and inhibitory synaptic transmission (E/I ratio) is importan

94 nstem slices, OXT perfusion had no effect on inhibitory synaptic transmission; following exposure to

95 These significant differences in inhibitory synaptic transmission form an important basis

96 A week of visual deprivation reduced inhibitory synaptic transmission from the thalamic retic

97 present study dissected fast excitatory and inhibitory synaptic transmission from the VTA to NAc MSN

98 Abnormalities in inhibitory synaptic transmission have been associated wi

99 cannabinoid-mediated long-term depression of inhibitory synaptic transmission (I-LTD) in the ventral

100 obutyric acid (GABA(A)) receptor and enhance inhibitory synaptic transmission in a manner similar to

101 that Ca2+-permeable AMPARs and CaN regulate inhibitory synaptic transmission in a novel plasticity p

102 this issue, we have assessed excitatory and inhibitory synaptic transmission in acute hippocampal sl

103 f this subunit alone is sufficient to rescue inhibitory synaptic transmission in beta1-beta3 triple k

104 Excitatory and inhibitory synaptic transmission in CA1 neurons was stud

105 rate significant physiological impairment in inhibitory synaptic transmission in experimental cortica

106 TA-associated inhibitory synaptic transmission in Fmr1 KO mice was als

107 antly reduces GABAergic synaptic density and inhibitory synaptic transmission in hippocampal CA1 neur

108 Here, we show that E2 rapidly suppresses inhibitory synaptic transmission in hippocampal CA1.

109 trocytes in activity-dependent modulation of inhibitory synaptic transmission in hippocampal slices.

110 ability in female CeA neurons, and increased inhibitory synaptic transmission in male CeA neurons.

111 GABAA receptor (GABAAR)-mediated current and inhibitory synaptic transmission in medium spiny neurons

112 that is caused by a long-term depression of inhibitory synaptic transmission in mice.

113 cterize the effects of N2O on excitatory and inhibitory synaptic transmission in microcultures of rat

114 ceptor activation suppresses the efficacy of inhibitory synaptic transmission in NAc by increasing th

115 rovide a novel and powerful form of feedback inhibitory synaptic transmission in one class of cortica

116 123 despite a nearly complete suppression of inhibitory synaptic transmission in Purkinje cells by th

117 Our results show that inhibitory synaptic transmission in Purkinje cells is ne

118 n, serotonin, and dopamine of excitatory and inhibitory synaptic transmission in specific brain regio

119 mutation (S346A) in GlyR alpha3 subunits on inhibitory synaptic transmission in superficial spinal d

120 d-gated ion channel superfamily that mediate inhibitory synaptic transmission in the adult central ne

121 d the hypotheses that acute EtOH facilitates inhibitory synaptic transmission in the BLA by activatin

122 Glycine receptors (GlyRs) contribute to fast inhibitory synaptic transmission in the brain stem and s

123 cid type A receptors (GABAA-Rs) mediate fast inhibitory synaptic transmission in the brain.

124 he GluR5 subunit have been shown to modulate inhibitory synaptic transmission in the CA1 region of th

125 found that at KOR signaling robustly reduced inhibitory synaptic transmission in the CeA to BNST path

126 protein-coupled receptors that mediate slow inhibitory synaptic transmission in the central nervous

127 ptors (GABA(A)-Rs) mediate the bulk of rapid inhibitory synaptic transmission in the central nervous

128 The GABRB2 mediates the fastest inhibitory synaptic transmission in the central nervous

129 opic GABA(B) receptors is essential for slow inhibitory synaptic transmission in the CNS, and disrupt

130 ulness as a novel drug target for modulating inhibitory synaptic transmission in the CNS.

131 (KACh) channels are key determinants of the inhibitory synaptic transmission in the heart.

132 MicroRNA 138-5p (miR-138-5p) controls inhibitory synaptic transmission in the hippocampus and

133 Inhibitory synaptic transmission in the hippocampus in m

134 at cause a selective presynaptic increase in inhibitory synaptic transmission in the hippocampus that

135 eceptor agonists have been shown to modulate inhibitory synaptic transmission in the hippocampus, but

136 for the synaptic localization of GABAARs and inhibitory synaptic transmission in the hippocampus.

137 ABAARs) are the principal mediators of rapid inhibitory synaptic transmission in the human brain.

138 OXT and AVP signaling promoted inhibitory synaptic transmission in the LS, which failur

139 is essential for Cl(-) homeostasis and fast inhibitory synaptic transmission in the mature CNS.

140 lity and in the modulation of excitatory and inhibitory synaptic transmission in the medulla oblongat

141 ioids recruit parvalbumin inputs to suppress inhibitory synaptic transmission in the mOFC.

142 8-5p as a regulator of short-term memory and inhibitory synaptic transmission in the mouse hippocampu

143 ort the discovery of long-term depression of inhibitory synaptic transmission in the mouse nucleus ac

144 and amphetamine depress both excitatory and inhibitory synaptic transmission in the NAc by a presyna

145 Thus, DA appears to depress inhibitory synaptic transmission in the NAc by reducing

146 ermine if KA receptor activation could alter inhibitory synaptic transmission in the NAcc as it has b

147 xcitatory synaptic transmission and suppress inhibitory synaptic transmission in the pain circuits.

148 PVI function, and changes in excitatory and inhibitory synaptic transmission in the PFC.

149 Corticosterone application attenuated inhibitory synaptic transmission in the PL via cannabino

150 inoid-dependent effects of corticosterone on inhibitory synaptic transmission in the rat PL were dete

151 e-sensitive glycine receptor (GlyR) mediates inhibitory synaptic transmission in the spinal cord and

152 recently-described nicotinic enhancement of inhibitory synaptic transmission in the spinal cord dors

153 These results suggest that opioids inhibit inhibitory synaptic transmission in the STN through the

154 n of the normal developmental progression of inhibitory synaptic transmission in Ts65Dn mice at a cri

155 and is known to reduce excitatory (but also inhibitory) synaptic transmission in many CNS areas, lea

156 With inhibitory synaptic transmission intact, the maximum fir

157 Because inhibitory synaptic transmission is a major mechanism of

158 The novel, late, NPY-mediated increase of inhibitory synaptic transmission is caused by modulation

159 Furthermore, gain modulation by inhibitory synaptic transmission is disabled in both aud

160 rated that this long-lasting decrease in the inhibitory synaptic transmission is evoked by astrocytic

161 Inhibitory synaptic transmission is known to play an imp

162 ed mTOR alters the balance of excitatory and inhibitory synaptic transmission, leading to hippocampal

163 Inhibitors of excitatory and inhibitory synaptic transmission made spike discharges m

164 These data suggest that increased inhibitory synaptic transmission may contribute to human

165 at changes in VTA-to-NAc fast excitatory and inhibitory synaptic transmissions may contribute to coca

166 nnels in modulating the action of ethanol on inhibitory synaptic transmission mediated via GABAA rece

167 profound alterations to both excitatory and inhibitory synaptic transmission onto deep layer project

168 unted dopamine response was due to increased inhibitory synaptic transmission onto dopamine neurons.

169 Patch-clamp recordings revealed increased inhibitory synaptic transmission onto IL projection neur

170 as lasting changes on firing, tonic GABA and inhibitory synaptic transmission onto lOFC neurons.

171 opioids induce a long-lasting suppression of inhibitory synaptic transmission onto OFC pyramidal neur

172 HDAC5 significantly increased inhibitory synaptic transmission onto PrL deep-layer pyr

173 unctionally drives GABA release and enhances inhibitory synaptic transmission onto proximal interneur

174 deficits in working memory and increases in inhibitory synaptic transmission onto pyramidal neurons

175 in postnatal development does not rejuvenate inhibitory synaptic transmission or facilitate rapid ocu

176 not accompanied by lasting changes in either inhibitory synaptic transmission or somatic excitability

177 t BDNF expression controls the plasticity of inhibitory synaptic transmission particularly when recov

178 Inhibitory synaptic transmission plays an important role

179 IPSCs, or disinhibition, in that blockade of inhibitory synaptic transmission prevents the effect of

180 europeptide Substance P, but not blockade of inhibitory synaptic transmission, reduced opioidergic ef

181 However, whether BDNF modulates inhibitory synaptic transmission remains to be firmly es

182 midal cells but does not alter excitatory or inhibitory synaptic transmission, responses thought to b

183 onse to dark exposure is the rejuvenation of inhibitory synaptic transmission, resulting in a decreas

184 ich could be important for the regulation of inhibitory synaptic transmission.SIGNIFICANCE STATEMENT

185 ppressed binge alcohol drinking by enhancing inhibitory synaptic transmission specifically in CRF neu

186 pposite effects to their parent molecules on inhibitory synaptic transmission, suggest that alteratio

187 This imbalance reflects a deficit in inhibitory synaptic transmission that appears to be seco

188 Despite unaltered inhibitory synaptic transmission, the disynaptic feedbac

189 y visual cortex enhances both excitatory and inhibitory synaptic transmission, through the activation

190 llowing a neuron to modulate the strength of inhibitory synaptic transmission to its changing require

191 o-photon glutamate uncaging, which preserves inhibitory synaptic transmission, to demonstrate that so

192 shifting the balance between excitatory and inhibitory synaptic transmission toward inhibition.

193 encoded the strength of synaptic input when inhibitory synaptic transmission was blocked.

194 Inhibitory synaptic transmission was increased in D2-MSN

195 synaptic transmission, because no change in inhibitory synaptic transmission was observed in the hip

196 oundly affected in these neurons, as well as inhibitory synaptic transmission, we found little pertur

197 Furthermore, inhibitory synaptic transmission, which gates experience

198 Instead, stimulation produced GABA-mediated inhibitory synaptic transmission, which suppressed the f

199 -deficient mice are ameliorated by enhancing inhibitory synaptic transmission with a GABAAR agonist.

200 l changes were accompanied by an increase in inhibitory synaptic transmission with no apparent effect

201 ese data support the hypothesis that reduced inhibitory synaptic transmission within the NAc plays a

202 ATP activates presynaptic P2X2Rs to regulate inhibitory synaptic transmission within the SCN and that

203 tissue damage induces long-term deficits in inhibitory synaptic transmission within the spinal super