ライフサイエンスコーパス: initially

1 ion changes for miR-155-5p with a range from initially 40 molecules/cell to 1600 molecules/cell upon

2 Initially, a conserved glutamate at the active site was

3 After P. falciparum initially acquired free cholesterol or inner erythrocyti

4 The enallene is initially activated by palladium and reacts with the all

5 Populations with severe TM defects initially adapted via mutations in the TM, but TM adapta

6 of the intermediates and products versus the initially added 6:2 FTS was close to 100% over the react

7 Even though parasites initially adhere to RBCs with a random orientation, they

8 HIV infection and COVID-19 death; they were initially adjusted for age and sex, then we added adjust

9 Initially, all cases were discussed via telemedicine, bu

10 longer differed significantly from patients initially allocated to clazakizumab.

11 monitoring, NO(2) removal efficiency was 96% initially and decreased to 61%; and BTEX removal efficie

12 of embryonic stem (ES) cells are most active initially and may gradually fade over time.

13 and Type 17 helper T (Th17) cells increased initially and promoted osteoclastogenesis.

14 rns observed in the experiments-the wrinkles initially appear either in the peripheral region and pro

15 y modular networks of orientation preference initially arise independent of visual experience, experi

16 -down) type, where alpha-synuclein pathology initially arises in the brain with secondary spreading t

17 e basic reproduction number of the virus was initially around 2.5, dropping by more than two-thirds f

18 ed with myocardial inflammation misdiagnosed initially as cardiac sarcoidosis or myocarditis.

19 encing of microbial communities, referred to initially as community genomics and subsequently as geno

20 Teeth initially assigned to a poorer prognosis category had a

21 At 1 year, patients initially assigned to monthly treatment were reassigned

22 xt-generation hormonal agent, those who were initially assigned to receive olaparib had a significant

23 suggest that genes such as SNX32, which was initially associated with increased risk of Alzheimer di

24 reak to a single patient rather than HCWs as initially assumed based on conventional epidemiology.

25 stence of greater genetic diversity than was initially assumed, splitting the PFGE-associated outbrea

26 ion enveloped posterior cortex when subjects initially became unconscious, but later encompassed both

27 cific influences on target networks than had initially been imagined.

28 x yet reversible shape transformations, from initially biconcave disks to elongated and folded geomet

29 However, kinetochores initially bind to microtubules indiscriminately, resulti

30 e attributed to the redistribution of water, initially bound by WU-AX, between the other flour consti

31 We show that the glial LDs initially buffer the cells against damage caused by glia

32 specific genotypes can be amplified, perhaps initially by cellular proliferation but further by limit

33 , but little is known of how they are shaped initially by patterns of breeding, selection, recombinat

34 Notably, these pDCs were initially capable of producing high levels of type I IFN

35 cCXCR5 T cells elicited by vaccination were initially CD38(+)ICOS(+)PD1(+), but then transitioned to

36 e action rates for general surgeons who were initially certified by the ABS from 1976 to 2005 and att

37 We initially characterized a yeast clone isolated for carry

38 Fibroblast growth factor 23 (FGF23) was initially characterized as an important regulator of pho

39 source of luciferin and SBF, we isolated and initially characterized these compounds.

40 Initially, children were thought to be spared from disea

41 egorization of 76% (47/62) of PVE/AAPI cases initially classified as "possible" to "definite" IE.

42 The previously unstudied variants were initially classified as likely benign (n = 2), likely pa

43 primary and promiscuous functions could have initially coexisted following I2 acquisition, paving the

44 Preoperative antibiotics were initially collected as first-generation cephalosporin, s

45 of the pelagic and profundal morphs in lakes initially colonized by the littoral morph.

46 noses in a large number of patients who were initially comatose, in whom the ultimate outcome is uncl

47 broad use of antibiotics can repeatedly lead initially commensal drug-susceptible bacteria to evolve

48 assical Norrish hydrogen atom abstraction as initially conceived.

49 Initially conceptualized as a respiratory disease, COVID

50 ary, PsychInfo, Google Scholar, Delphis) was initially conducted in May 2017 (repeated August 2018).

51 A search using Ovid MEDLINE and Embase was initially conducted to identify studies on severe Plasmo

52 No nurses declined to participate after initially consenting.

53 <17 mm was noticed in both patients managed initially conservatively (adjusted HR, 1.46 [95% CI, 1.2

54 bstantial child health benefits beyond those initially considered.

55 In chronically infected animals with viremia initially controlled by combination antiretroviral thera

56 Initially, corrosion etch pits are formed, which reflect

57 We initially cover the biodegradation of graphene family ma

58 ncluded patients who had cCR after nCRT, who initially declined surgery, and who subsequently underwe

59 disease in 46% of patients with DCM who were initially deemed nonfamilial by history.

60 We initially demonstrated that nsp8 and nsp12 form an activ

61 ited studies with the V- and Fe-nitrogenases initially demonstrated that these enzymes were analogous

62 shear and membrane surface properties on the initially deposited anaerobes.

63 Initially described in 1978, recognition of these disord

64 Though the SN was initially described in humans, identification of a roden

65 aggressive neuroendocrine derivatives - was initially described in lung cancers harbouring an EGFR m

66 PEDF) is a multifunctional protein which was initially described in the retina, although it is also p

67 biological functions that go far beyond its initially described role as a simple information carrier

68 osis, which appears to be more frequent than initially described.

69 reserved skulls of a fossil hominin, and was initially designated as the type specimen of Homo rhodes

70 Initially designed to assess the nation's progress in co

71 Peaks in a modulated chromatogram were initially detected by conventional chromatographic integ

72 to 2017; EsVan2: October 2017 to 2019) were initially developed and subsequently implemented for cli

73 Although initially developed as a theranostic ligand for metastas

74 tively weighted Fisher's method (AW-Fisher), initially developed for omics applications but applicabl

75 orting the concept that PI3Kdelta inhibitors initially developed for oncology have immune regulatory

76 human keratinocytes and fibroblasts and was initially devoid of skin-resident immune cells.

77 xia, dysphagia and unintentional weight loss initially diagnosed as achalasia.

78 There were 165 (89.7%) infants initially diagnosed by a non-ophthalmology care provider

79 nd (5) recurrent HZ identified from a cohort initially diagnosed with HZ in 2007-2008 and followed th

80 In 3-year follow-up study of individuals initially diagnosed with PTSD (N = 26), changes in PTSD

81 ents, but a substantial fraction of patients initially diagnosed with sepsis have noninfectious condi

82 ylinder on a reversible commitment requiring initially disabling indoor chulhas.

83 n 3E (Sema3E) is a secreted protein that was initially discovered as a neuronal guidance cue.

84 Initially discovered in Drosophila, the Hippo pathway ha

85 Hence, in this piece of work, we have initially discussed the global statistics of neurologica

86 in rewinding of the 2 turns of DNA that were initially disrupted.

87 Our study reveals that the initially distributed wrinkles tend to coalesce to form

88 drugs daunorubicin and verapamil, which were initially docked into the ABC transporter, get transloca

89 g 5S rRNA, rpL5, rpL11, Rpf2 and Rrs1, which initially docks onto the flexible domain V of rRNA at ea

90 n of approximately 50% of the genes that are initially downregulated by PRMT5 inhibition, suggesting

91 l lymphoma (MCL) is a mature B-cell neoplasm initially driven by CCND1 rearrangement with 2 molecular

92 While initially effective, the cancer almost always recurs as

93 Our study initially employed point-of-care testing methods but thi

94 ity, while producing clean catholyte into an initially empty cathode chamber through the process of e

95 nd on processes that unfold after events are initially encoded into memory.

96 A total of 45 patients were initially enrolled in the study, of whom 43 received an

97 mechanism is that chromatin decompaction is initially established during embryogenesis and maintaine

98 gent Biology and Medicine (ICIBM), which was initially established in 2012.

99 The patient's liver metastasis was initially established subcutaneously in nude mice and th

100 Phenotype and function of cT(FH) cells were initially evaluated in the grass pollen-allergic (GPA) g

101 After initially evaluating the reproducibility of StatDns acro

102 In the current study, we initially examined differences in the quantity, diversit

103 We initially extracted fifty SNPs associated with UNa at si

104 CR-2 producer remained, as the isolates with initially faintly positive results were negative.

105 biomes, consistent with biotic interactions initially favouring the accumulation of diversity (as pr

106 Female Dahl salt-sensitive rats were initially fed with either low salt (LS) or high salt (HS

107 Expanding biofilms are initially flat but later undergo a mechanical instabilit

108 tial and temporal shape evolution within the initially flat shell.

109 Initially focused on neurons alone, the field has follow

110 We initially focused our attention on generalized pustular

111 tic studies showed the binding of POT1 to an initially folded 24 nt G-quadruplex structure is four or

112 GFP11 and PBG98-VP1-TC viruses, discrete VFs initially formed from each input virus that subsequently

113 Discrete VFs initially formed from each virus that subsequently coale

114 ronments and the facile overoxidation of the initially formed hydroxylation product.

115 pearing capable of rapid aggregation, albeit initially forming smaller, weakly self-associated, acute

116 Together, we initially found that RGFP966 alleviated the inflammatory

117 -assembling glutamine amide derivative 1 was initially found to catalyze a model aldol reaction betwe

118 ved from case-control studies or populations initially free of disease.

119 Both haematological and solid cancers initially gain chromosome arms, while only solid cancers

120 The six-species hybrids initially grow slowly, but they rapidly regain fitness a

121 These corals initially had heat-sensitive algal symbiont communities,

122 colorectal, lung, and prostate cancer among initially healthy individuals.

123 whether it also determines cancer risk among initially healthy individuals.

124 specially because of plant diversity loss in initially high diversity communities.

125 y receptors compared with CD8+ T cells, with initially high expression levels of PD-1 and CTLA-4 that

126 Mice with initially high titers of HBV and knockdown of HBV antige

127 Furthermore, subjective cure rates, although initially high, also deteriorate over time.

128 In hermaphrodites, neuronal expression is initially highly restricted and then increases variably

129 We initially identified 37 patients with Shwachman-Diamond

130 rome and Sequential Organ Failure Assessment initially identified distinct populations.

131 kinase 3 (MLK3), also known as MAP3K11, was initially identified in a megakaryocytic cell line and i

132 It was initially identified in pig leukocytes with a broad-spec

133 We initially identified Ser-359 phosphorylation by MS analy

134 From 18 initially identified surface proteins, only SPy_2191 is

135 amed by the distinct regions where they were initially identified, have been defined.

136 tion in a first-of-its-kind biphasic manner, initially impeded and then facilitated with increasing Z

137 se large B-cell lymphoma (DLBCL) may present initially in bone marrow, liver and spleen without any l

138 search was conducted in the PubMed database initially in January 2018 and updated in July 2019 to id

139 form of non-Hodgkin lymphoma that manifests initially in the skin and disseminates systemically as t

140 Other benefits initially included attenuation correction of SPECT recon

141 even of the approximately 100 serotypes were initially included in the pneumococcal polysaccharide co

142 in diagnosis is common with 55% of patients initially incorrectly diagnosed with chronic inflammator

143 c materials have in many cases been found to initially increase with increasing thermal disorder and

144 nivolumab in WT mice, even though nivolumab initially increased mechanical and thermal pain.

145 The mechanical performance initially increased with MCF and then decreased.

146 The ACC strength initially increases due to changes in the wind stress, t

147 s underwent at least one additional CT scan (initially indeterminate).

148 hough laparoscopic liver resection (LLR) was initially indicated for small benign and peripheral tumo

149 n broiler flock even if only one chicken was initially infected.

150 he control (1.2) indicating that stimulation initially inhibited growth but resulted in eventual adap

151 This drives an initially inhomogeneous interfacial water coordination l

152 Each animal was initially injected intravenously with unlabeled antibody

153 These initially innate behaviors depend critically upon coordi

154 When phenylene bridges are initially inserted between a CdSe nanocrystal donor and

155 Phytoene overproduction initially interferes with photosynthesis, acting as a me

156 actinides (An, from Ac to Lr), Ti, and Zr is initially introduced.

157 The coverage is structured by initially introducing the basic features of these method

158 ance to its close relative from which it was initially invented, namely Principal Component Analysis

159 Both pathways initially involve the release of free arachidonic acid a

160 Initially, JQ1 enhanced motor performance in NT mice.

161 r mutants have similar growth defects, which initially led to the assumption that the signaling pathw

162 While SFG studies were initially limited to simple model peptides, the past dec

163 Initially lipid-rich, pathogen thalli become increasingl

164 H2A.Z initially localizes downstream of the transcription star

165 vagal and sacral neural crest cells that are initially located at the border of the neural tube.

166 cGAS was initially located in the cytosolic compartment of pDCs a

167 very following stroke were based only on the initially lost motor function, at least for a specific f

168 s models, inflammatory cell infiltration was initially lower in knockout mice but later increased, le

169 ement, defined as the proportion of patients initially managed nonoperatively who did not undergo app

170 clones were inferred to have originated and initially matured in the thymus before emigration from t

171 illance programs for invading pathogens must initially meet challenges that include low rates of occu

172 Overall, fluorosis severity, which was initially mild to moderate, tended to decline during ado

173 Ninety percent of our cases were initially misdiagnosed as PAX6-related phenotype or ocul

174 Although initially more dissolved As was detected in the acetate/

175 3 from key bivalent genes, while H3K27me3 is initially more stable but lost following extended cultur

176 in part by accelerated nitrification on the initially more-fertile soils.

177 cells were infected with HCV, suggests that initially most secreted HCV RNA derives from intracellul

178 results in a reverse epitaxial process where initially nanocrystalline Au films gain texture, crystal

179 After 14 weeks, 116 of 445 (26.1%) initially negative contacts were IGRA converters; 317 (7

180 Initially negative tests typically remained negative, wh

181 ests (which can be minimized when re-testing initially negative tests).

182 all initial tests, initially positive tests, initially negative tests, or no re-testing.

183 playing to ensure their propagation, so that initially nonessential processes secure a genetic herita

184 Spontaneous digging behaviour was initially normal and only declined in mutants in the sec

185 iously unreported molecular type (ST-13578), initially observed in Israel in 2014.

186 a model where C(4) evolution in Neurachninae initially occurred via an increase in organelle and GLDP

187 iloted a rapid WGS (rWGS) workflow, focusing initially on estimating power for a feasibility study of

188 maintains melanosome neutralization that is initially orchestrated by transient OCA2 activity to sup

189 nclude a recurrent splicing variant that was initially overlooked due to its deep-intronic location.

190 Initially overlooked in favor of T cell-mediated rejecti

191 naling causes the cell to polarize even when initially overstimulated.

192 This review initially overviews the complex structural features of m

193 Initially, PCR methods targeted the 35-fold repetitive B

194 ial complex, translocated into the nuclei of initially penetrated and surrounding cells, and reprogra

195 structure analysis and in vitro binding data initially pointed towards a simple competition mechanism

196 The finding that the spin of the initially populated FC excited state differs from that o

197 He initially posited that nonnative species closely related

198 least 12 weeks later in 77%, 45%, and 41% of initially positive LA, aCL, and aGP1, respectively.

199 e tests typically remained negative, whereas initially positive tests mostly remained positive until

200 ng scenarios of repeating all initial tests, initially positive tests, initially negative tests, or n

201 peripheral input, suggesting that the AL is initially pre-patterned and later refined in an OSN-depe

202 s (ethane, propane, butane, and pentane) are initially produced by irreversible cracking chemistry, b

203 Initially, progress in the nascent field of synthetic bi

204 Specifically, Pbx4 initially promotes the partitioning of the SHF into ante

205 Hyperbolic metamaterials were initially proposed in optics to boost radiation efficien

206 The majority of the initially proposed methods for gene regulatory network d

207 ne T cells in atherosclerosis and suggest an initially protective autoimmune response against apoB wi

208 Of 169 patients (age range, 4-17 years) initially randomized in the 4-month VErnal Keratoconjunc

209 The patients were initially randomized to nonoperative treatment with anti

210 Of these, 28 patients were initially randomly assigned to receive a low (5 x 10(7))

211 iotracer clearance from blood and plasma was initially rapid (blood half-time, 1.31 +/- 0.81 min; pla

212 s having significant fitness advantages when initially rare.

213 ions support a mechanism whereby the borepin initially rearranges to a boranorcaradiene by a thermal

214 ants whose eyes were assigned to aflibercept initially received 4 monthly injections.

215 ed treatment, 104 underwent ablation, and 99 initially received drug therapy.

216 ho initiated ocrelizumab early than in those initially receiving placebo for most of the measures of

217 However, it is not clear how RNA polymerase initially recognizes such sequences.

218 predictor of memory decline in participants initially recruited in ADNI as healthy adults.

219 While speciation should initially reduce genetic variation in daughter versus pa

220 rgeting the coding region of some mRNAs that initially reduce target mRNAs can surprisingly increase

221 lly, we found that 1) social distancing must initially reduce the transmission rate to within a narro

222 The AMOC strength is initially reduced and then undergoes a slow and partial

223 inducing the enhancement is explained by the initially reparable pores generated by LEEFT that cannot

224 ce the number of genes with APA changes than initially reported.

225 In the insect olfactory system, odors are initially represented in the periphery as a combinatoria

226 ated by heat-tolerant symbionts, and despite initially resisting bleaching, these corals had no survi

227 Although many ccRCC patients initially respond to antiangiogenic therapies, virtually

228 advanced-stage prostate cancer patients will initially respond to the androgen deprivation, the disea

229 Most patients initially responded to SLT, but the majority failed with

230 Despite initially responding to FLT3 inhibitors, most patients e

231 Advanced prostate cancer initially responds to hormonal treatment, but ultimately

232 While initially restricted to clinical settings, drug resistan

233 nce demonstrates that senescent cells, while initially restricting tumorigenesis, can induce tumor pr

234 fibromin-deficient ER(+) breast cancer cells initially retain sensitivity to selective ER degraders (

235 ach time DNA replicates, PRC2-deficient ISCs initially retain sufficient H3K27me3 to avoid gene derep

236 of PLHIV with presumptive TB in whom TB was initially ruled out.

237 We initially screened a library with a large structural var

238 ored how interactions between Acr phages and initially sensitive bacteria evolve, both in the presenc

239 nrolled from 2015 to 2018, including 75 with initially shockable rhythms.

240 myosin heads to an ordered resting state was initially slower, then became more rapid than in WT musc

241 Tracheids in the post-scarring wood are initially smaller, and then become larger than average f

242 The anchor cell is initially specified in a stochastic cell fate decision m

243 Initially, steric clashes of the Mtf1 C-tail with short

244 feedback mechanism whereby transcribed RNAs initially stimulate but then ultimately arrest the proce

245 sion suggested that sunlight exposure of DOM initially stimulated microbial growth by (i) replacing t

246 AA subjects (n = 270) were initially studied between 1994 and 2006 and standardized

247 Our QTL results initially suggested that differences in male mate choice

248 S limitation through TIGAR has been shown to initially support cancer development but to later become

249 -induced increase in ENSO variability(29) is initially suppressed by internal variability, future ENS

250 f moderate to strong spatial correlation was initially surprising because secondary aerosol contribut

251 -term mortality and morbidity among children initially surviving sepsis, is unknown.

252 ial picture of the outbreak by 1) ruling out initially suspected cases, 2) defining likely independen

253 She was initially suspected of having flu, and she completed a c

254 She was initially suspected of having flu, and she completed a c

255 He was initially suspected to have concurrent gallstone cholang

256 uctive isolation of nascent species that are initially sympatric with one or both parents.

257 Initially, tensile specimens of a Co-added stainless ste

258 Initially tested with model systems with solid conductiv

259 Initially, the addition of equimolar SnSe and SnS in the

260 Initially, the different compositions of ZnO nanorods (N

261 Initially, the global burden of CVDs and the standard of

262 Initially, the molecule binds to a lattice O(2)(-) ion t

263 Initially, the NP sublimation rates were ~400 times fast

264 Initially, the predominant view of cohesin was as a ring

265 Initially, these cells are seeded as a proliferative mon

266 Initially, these outflows contain only protons and neutr

267 Initially, these transcription factors function independ

268 evealing the process to be more complex than initially thought, especially with respect to the role o

269 namic receptor complexes that vary more than initially thought.

270 er range of critical roles in cells than was initially thought.

271 mplemented a new drug class and have used it initially to annotate drugs relevant to cardiovascular d

272 55, cooperativity is abolished and p53 binds initially to cognate DNA sites as a dimer.

273 g/V initially tracks the current, increasing ~15-fold from t

274 otal of 234 patients with exudative AMD were initially treated with 3 monthly IAI and thereafter as-n

275 The patient was initially treated with benralizumab, which resulted in m

276 with laser therapy compared with 19 infants initially treated with bevacizumab at 24 hours (40% vs.

277 Of patients initially treated with broad-spectrum antibiotics, most

278 significantly less common among 119 infants initially treated with laser therapy compared with 19 in

279 developed new bilateral lower extremity rash initially treated with levofloxacin for presumed celluli

280 Acute graft-versus-host disease (GVHD) is initially triggered by alloreactive T cells, which damag

281 Although initially uncommon, reports of the African clade in the

282 Intrachromosomal amplifications that formed initially under low-level drug selection underwent conti

283 ADP-evoked fibrinogen binding was initially uniform over the cell periphery but subsequent

284 epithelial surfaces within the centre of an initially unpolarised, solid organ.

285 generalised state equation, we show that an initially unstable system can be rendered stable via a r

286 data suggest that a MLCT state is generated initially upon excitation but decays to a long-lived sta

287 Although initially used primarily for treatment intensification f

288 It was initially used to boost immune responses in patients wit

289 management strategies regardless of which is initially used.

290 Initially viewed as receptors whose signaling via G prot

291 tional on the baseline climate, such that in initially warmer locations richness increase is more pro

292 Initially water decorates the metal channels, hydrogen b

293 Initially, we consulted with community advisory boards a

294 Initially, we demonstrate the power of CSP to rationaliz

295 Initially, we focused on identifying spontaneous adenosi

296 Initially, we used many consensus tools of SIFT, PROVEAN

297 Results Consensus on reference values was initially weak for 232 of 302 features (76.8%) at phase

298 ength PfCSP, denoted PfCSP4/38, was produced initially with a histidine tag and purified by a simple

299 dults with biopsy-proven B-cell PTLD treated initially with R-Mono or Rituximab plus CHOP (R-CHOP).

300 Animals treated initially with tacrolimus and converted to PRCL-02 monot