ライフサイエンスコーパス: injurious

1 ete development, whereas excess copper maybe injurious.

2 tory of severe hypoglycaemia is perhaps less injurious.

3 but conflicts can be time-consuming and even injurious.

4 of reperfusion, such as inflammation, may be injurious.

5 t renders the livers more susceptible to the injurious actions of other fibrotic stimuli.

6 = .04) across all suicide attempts and self-injurious acts combined.

7 tory response to adipokine visfatin, a major injurious adipokine during obesity.

8 auma or microbial invasion that destroys the injurious agent and the injured tissue.

9 otects organisms by removing or neutralizing injurious agents.

10 tudies may identify initial, and potentially injurious, altered processes.

11 Excretory pore plugs are injurious and hermaphrodite activity is compromised in p

12 ically increased in response to a variety of injurious and inflammatory insults.

13 The dependent variables were self-reported injurious and noninjurious violence during follow-up.

14 study entry, comprised participants' recent injurious and noninjurious violence, demographic and bac

15 Sciences-sponsored ND dataset comprising 905 injurious and property damage crash events, the magnitud

16 ng of Ngal-Luc2-mC mice and cells identified injurious and reparative agents that affect kidney damag

17 eurobehavioral abnormalities, including self-injurious and risk-taking behaviors, hyperactivity, and

18 spacing of brain cells and blood vessels, is injurious and triggers ischemia, gliosis, and cell death

19 e expected, inducing inflammatory, adaptive, injurious, and reparative processes.

20 relevant pharmacological strategy to reduce injurious angiopoietin-2 synthesis.

21 ApoE was not protective, but was injurious, as deletion of ApoE delayed the neurodegenera

22 Self-injurious behavior (SIB) is a complex condition that exh

23 Self-injurious behavior (SIB) is among the most dangerous con

24 autism spectrum disorder (ASD) display self-injurious behavior (SIB) ranging from head banging to se

25 ns endorse suicidality, and the rate of self-injurious behavior and suicide are markedly higher than

26 ty and elicited profound stereotypy and self-injurious behavior at 30 mg/kg.

27 nied by severe tantrums, aggression, or self-injurious behavior in children 5 to 17 years old.

28 e treatment of tantrums, aggression, or self-injurious behavior in children with autistic disorder.

29 The management of nonsuicidal self-injurious behavior is a common focus of clinical care, p

30 nd with recent and repeated suicidal or self-injurious behavior were compared in nine areas of functi

31 as triggers to impulsive, suicidal, and self-injurious behavior, affective reactivity, and angry outb

32 Tic severity, OCD, ADHD, self-injurious behavior, and exposure to a variety of prenata

33 of psychopathology such as aggression, self-injurious behavior, property destruction, and pica; and

34 al manifestations, including compulsive self-injurious behavior.

35 icit hyperactivity disorder (ADHD), and self-injurious behavior.

36 tic behavioral abnormalities, including self-injurious behaviors and sleep disturbance, and distinct

37 on measures of suicidal and nonsuicidal self-injurious behaviors, health care utilization, general sy

38 ain, including suicidal and nonsuicidal self-injurious behaviors.

39 activity, and increased risk-taking and self-injurious behaviors.

40 ayer-to-player contact and other potentially injurious behaviors.

41 includes mental retardation, recurrent self-injurious behaviour and motor disability.

42 review literature published in 2004 on self-injurious behaviour in individuals with intellectual dis

43 iewed published studies of relevance to self-injurious behaviour in people with intellectual disabili

44 demonstrate the multiple influences on self-injurious behaviour that must be taken into account in t

45 rum disorders, biological influences on self-injurious behaviour, behavioural assessment and psycholo

46 The review covers the prevalence of self-injurious behaviour, the characteristics of those showin

47 ized dystonia, cognitive disability and self-injurious behaviour.

48 Self-injurious behaviours (SIBs) are defined as deliberate, r

49 Though none exhibited self-injurious behaviours, many exhibited behaviours that wer

50 t mdx muscle fibres are depolarized after an injurious bout of eccentric contractions.

51 Despite major efforts to minimize injurious but often life-saving postnatal interventions

52 receptor NR2B subunit in vivo in mice blocks injurious Ca(2+) influx through NMDA receptor channels a

53 onal intracellular Ca(2+)-homeostasis in the injurious cascade associated with axonal degeneration.

54 ered podocyte actin cytoskeleton, leading to injurious cellular biomechanics.

55 an initial insult that triggers a cascade of injurious cellular processes.

56 sue responses to many acute inflammatory and injurious challenges, whereas proinflammatory and cell s

57 m, sensitizes mice to acute inflammatory and injurious challenges.

58 Our study demonstrates a highly injurious combination of TLR4-mediated NFKB signalling,

59 s increased atherosclerotic risk because the injurious component of atherosclerosis exceeds the repai

60 e subjected to uniaxial, radially-unconfined injurious compression (50% strain; 100%/second strain ra

61 Injurious compression also caused increased release and

62 Injurious compression caused the release of intracellula

63 Injurious compression of articular cartilage induces an

64 Following injurious compression of the cartilage, matrix metallopr

65 les showed little change in expression after injurious compression, whereas MMP-3 increased approxima

66 sient response of surface-layer cartilage to injurious compression.

67 , and 24 hours after application of a single injurious compression.

68 he adult heart and is induced in response to injurious conditions that promote myocardial hypertrophy

69 matory responses within the CNS milieu under injurious conditions, involving CD200 ligand (CD200L) ex

70 of electrical stimulation, such as occurs in injurious conditions, on P2X receptor-mediated ATP respo

71 To determine the role of P2X receptors under injurious conditions, we examined ATP-evoked responses i

72 r the survival of kidney tubular cells under injurious conditions.

73 he P2X7R-P2Y1-P2X3R inhibitory control under injurious conditions.

74 in the sensitization of P2X receptors under injurious conditions.

75 is a hallmark of these pathologies and other injurious conditions.

76 sue results in oxidative stress with various injurious consequences such as inflammation and fibrosis

77 of cardiac allografts leads to production of injurious cytokines and expression of proinflammatory ad

78 s and/or macrophages that produce a storm of injurious cytokines.

79 the critical organ in determining the lowest injurious dose for (2)(1)(0)Po.

80 hanisms by which respiratory rate may become injurious during mechanical ventilation can be distingui

81 and high-risk underlying comorbidities, the injurious effect of COVID-19 on the liver, the inability

82 S1 transgenic mice are protected against the injurious effect of IFN-gamma.

83 ice, suggesting that CD4 T cells mediate the injurious effect of IL-33.

84 To determine whether microglial cells exert injurious effects after neonatal focal stroke, we select

85 line morphology or morphometry but truncated injurious effects in prevention and recovery rat models

86 Whether COX-2 induces cerebroprotective or injurious effects is probably dependent on which downstr

87 rovide evidence that hypoxia may amplify the injurious effects of anti-SSA/Ro antibodies.

88 Coactivating TLR2 reduced the injurious effects of dectin-1 activation.

89 the lung may be particularly susceptible to injurious effects of FRH.

90 mune functions of neutrophils but reduce the injurious effects of increased neutrophil longevity duri

91 shock with LeTx may be related to the direct injurious effects of lethal factor on endothelial cell f

92 on of the acinar cell is responsible for the injurious effects of low pHe on the exocrine pancreas.

93 iated increase in TAC uptake blunted the pro-injurious effects of LPS, suggesting a synergistic anti-

94 mitochondrial delivery may contribute to the injurious effects of neurotoxins.

95 otective effects of LSS while inhibiting the injurious effects of OSS.

96 odegenerative diseases and contribute to the injurious effects of other oxidative pathologies in the

97 protected to a much greater extent from the injurious effects of reduced-size liver ischemia and rep

98 of critical care physicians to the potential injurious effects of respiratory rate insensitivity to c

99 iet-induced hepatic UPR activation and other injurious effects of the MCD diet including hepatic chol

100 rier enhancement was sufficient to block the injurious effects of thrombin, TNF-alpha, and H2O2 in si

101 ritis model through prevention of the direct injurious effects of TWEAK on the filtration barrier and

102 rated by the respiratory muscles may lead to injurious effects on a regional level.

103 physiological roles with both favourable and injurious effects on human health.

104 how environmental factors may influence the injurious effects on the brain of a neurotoxin such as l

105 PQ(2+)) is a prototypic toxin known to exert injurious effects through oxidative stress and bears a s

106 production of prostaglandins that have many injurious effects.

107 tered perioperatively to compensate for the "injurious" effects of anaesthesia.

108 nd P0.1vent to detect predefined potentially injurious effort was tested using derivation and validat

109 Tachycardia exacerbates injurious episodes of myocardial ischemia and significan

110 block was sufficient to prevent these acute injurious events in metabolically compromised neurons.

111 at muscularization represents one of several injurious events to the pulmonary artery that may collec

112 Injurious events were reduced by 70% (202 in controls co

113 ave the capacity to sensitise in response to injurious events, and their loss in ageing may predispos

114 therapeutic benefit against a wide array of injurious exposures.

115 production of biologically active and tissue injurious factors by the ischemic gut.

116 buried glands, especially when challenged by injurious factors, remains largely unknown.

117 icut, we matched 122 hospitalizations for an injurious fall (59 hip-fracture and 63 other fall-relate

118 tly increased the likelihood of incurring an injurious fall during the 3-year follow-up period.

119 nits) or in the number of patients who fell, injurious fall rates, or the number of patients physical

120 llow-up, 67 men and 194 women experienced an injurious fall, and over 10 years of follow up, 203 men

121 1 [95% CI, 0.98-2.04]), and 4.9% vs 5.5% for injurious falls (HR, 0.91 [95% CI, 0.65-1.29]).

122 NRICA, there was a tendency to lower risk of injurious falls among those consuming caffeinated coffee

123 Injurious falls and fall-related hospitalizations.

124 rventions were associated with lower risk of injurious falls compared with usual care.

125 le is known about the deleterious effects of injurious falls relative to those of other disabling con

126 in men than in women, its impact on risk of injurious falls seems to be greater in men.

127 offee consumption and the risk of >=1 falls, injurious falls, and falls with fracture in older people

128 may be associated with premature mortality, injurious falls, bone fracture, and disability.

129 associated with increased rates of low BMI, injurious falls, incontinence, and vision loss.

130 ere was no association of severe sepsis with injurious falls, incontinence, vision loss, hearing loss

131 ased risk of so-called geriatric conditions (injurious falls, low body mass index [BMI], incontinence

132 d acute kidney injury or failure, but not of injurious falls, were higher in the intensive-treatment

133 in the association between pain and incident injurious falls.

134 ual care, were associated with reductions in injurious falls: exercise (odds ratio [OR], 0.51 [95% CI

135 d to friendly signals, and to defend against injurious foes.

136 or one patient but inadequate or potentially injurious for another.

137 etes) and one individual who engaged in self-injurious head banging behaviour.

138 Haemonchus contortus is arguably the most injurious helminth parasite for small ruminants.

139 Anesthetized mice were ventilated with injurious high tidal volume ventilation for periods up t

140 Injurious home-cage aggression (fighting) in mice affect

141 o not damage tissues directly, but induce an injurious host inflammatory response at the infected sit

142 rs of DRB1*04 are protected from some of the injurious hyperglycemic effects related to nephropathy.

143 Neurons preconditioned with non-injurious hypoxia or the anesthetic isoflurane express d

144 lammasome complex, resulting in IL-1beta and injurious IL-17A production.

145 ession, leading to AVM formation and a rapid injurious impact on heart function.

146 The scavenger receptor CD36 is injurious in acute experimental focal stroke and neurode

147 aling through the C5a-C5aR axis thus appears injurious in the acute period but serves a protective an

148 paired adenosine-5'-triphosphate release was injurious in vivo, in part through increased red blood c

149 Flunarizine was also able to block the injurious increase of Angpt-2 in murine endotoxemia in v

150 f T cell-mediated immune regulation to limit injurious inflammation during chronic infection.

151 tors, and pathways implicated in this tissue-injurious inflammation.

152 is is essential for clearance of potentially injurious inflammatory cells and subsequent efficient re

153 culatory system, triggering a vigorous, self-injurious inflammatory host response.

154 tive host defense mechanisms and potentially injurious inflammatory processes must be maintained.

155 cent and only poised to initiate potentially injurious inflammatory reactions via immune complex form

156 torm is an intensified, dysregulated, tissue-injurious inflammatory response driven by cytokine and i

157 avage of PLTP by cathepsin G may enhance the injurious inflammatory responses that occur in COPD.

158 rohibit or more closely regulate potentially injurious ingredients and thus promote public safety.

159 The confident identification of injurious ingredients within HDS will require strategic

160 ess respiratory drive and detect potentially injurious inspiratory effort.

161 ng axis over the sustained JNK-elevation and injurious insulin resistance in CHIP(-/-)-livers apparen

162 esophageal epithelium when it is faced with injurious insults.

163 Injurious ischaemia induced upregulation of gene express

164 By contrast, preconditioning followed by injurious ischaemia resulted in pronounced downregulatio

165 artery for 15 min (preconditioning), 60 min (injurious ischaemia), or preconditioning followed 72 h l

166 with little overlap among the conditions of injurious ischaemia, ischaemic preconditioning, or both.

167 ), or preconditioning followed 72 h later by injurious ischaemia.

168 a produces resilience to subsequent normally injurious ischemia.

169 ischemia applied at a remote site during an injurious ischemic event (remote postconditioning [RPost

170 2) the ability of P0.1 to detect potentially injurious levels of effort, and 3) how P0.1vent displaye

171 mechanosensitive ion channels functioning at injurious levels of strain.

172 tured in the arterial wall, activates tissue-injurious macrophages.

173 s indicate that disodium cromoglycate blocks injurious mast cell degranulation specifically without a

174 3 days, groups of samples were subjected to injurious mechanical compression (single uniaxial unconf

175 This study was undertaken to determine if injurious mechanical compression of cartilage explants r

176 proteoglycan (PG) degradation after in vitro injurious mechanical compression, including up-regulatio

177 as induced by saline lung lavage followed by injurious mechanical ventilation in 14 anesthetized pigs

178 Exposure to a combination of hyperoxia and injurious mechanical ventilation resulted in further mor

179 th decreased patient exposure to potentially injurious mechanical ventilation settings.

180 s induced by lung lavages and 210 minutes of injurious mechanical ventilation using low positive end-

181 We hypothesized that injurious mechanical ventilation will increase circulati

182 ung injury (surfactant depletion followed by injurious mechanical ventilation) group and ventilated w

183 brane disruptions during another modality of injurious mechanical ventilation, i.e., mechanical venti

184 ial treatment, hospital-acquired aspiration, injurious mechanical ventilation, transfusion, and fluid

185 induced by the combination of hyperoxia and injurious mechanical ventilation.

186 s and lung parenchyma depends on the type of injurious mechanical ventilation.

187 ome was induced by repeated lung lavages and injurious mechanical ventilation.

188 s induced combining saline lung lavages with injurious mechanical ventilation.

189 e intratracheal LPS treatment is followed by injurious mechanical ventilation.

190 de the ability to rest the lungs by avoiding injurious mechanical ventilator settings and the potenti

191 uppresses proinflammatory mediators and cell injurious mechanisms in the developing brain, and postin

192 that are either antiproteinuric or may block injurious mechanisms of proteinuria.

193 nd accumulate free cholesterol, which causes injurious membrane effects.

194 ver, are periodically exposed to potentially injurious microbes and/or microbial products.

195 ocytes displayed a greater susceptibility to injurious morphologic findings induced by neutrophil gra

196 Eighty-nine adolescents who were not self-injurious (N=36) or had recently engaged in nonsuicidal

197 the excessive intracellular accumulation of injurious Na(+) and Ca(2+) and is over-expressed in acut

198 present clear examples of the protective and injurious nature of NO. therapy in I-R.

199 Adenosine, released by cells in an injurious or hypoxic environment, possesses potent anti-

200 In response to injurious or infectious agents caspase-1 activating mult

201 can trigger diverse signaling pathways with injurious or pro-survival consequences.

202 that can be slippery, abrasive or otherwise injurious or uncomfortable.

203 able it to react with and detoxify otherwise injurious oxidants.

204 ent, thereby shifting the balance toward the injurious pathway.

205 This exaggerated injurious phenotype was absent in Cfh(-/-) mice deficien

206 barrier repair and facilitates formation of injurious platelet-neutrophil aggregates, contributing t

207 The injurious potential of inflammatory mediators might have

208 esponse to infection, which is a progressive injurious process that falls under the generalized term

209 gical importance of oxidative stress-induced injurious processes in chagasic heart dysfunction.

210 frequent presence and overlap of concomitant injurious processes, including hepatitis C virus and hep

211 tion is a cause, or merely a consequence, of injurious processes.

212 in mitochondrial DNA, a proinflammatory and injurious product of cellular necrosis, in cell-free bro

213 topoietic stem cells, mediated by both their injurious renal and systemic actions.

214 mice with Shank3 gene deletions exhibit self-injurious repetitive grooming and deficits in social int

215 and dendritic cells) promote immune-mediated injurious responses in the failing heart and retain this

216 T1) deacetylase during lung inflammatory and injurious responses.

217 gulation of CS-induced lung inflammatory and injurious responses.

218 s responsible for dysregulated repair during injurious responses.

219 of lung function, enhanced emphysematous and injurious responses.

220 t genetic studies have strongly supported an injurious role for complement in a wide array of human i

221 Having recently described the injurious role of caspase-1-mediated production of the p

222 increased hepatic warm IR injury, suggesting injurious roles of DC infusion.

223 e convergence of Ca(2+)- and Zn(2+)-mediated injurious signaling pathways, providing a potentially un

224 Ischemic stroke results in multiple injurious signals within a cell including dysregulation

225 ive potential of the acinar cell to mitigate injurious states such as pancreatitis.

226 ghts into how the kidney responds to various injurious stimuli and allow evaluation of new therapeuti

227 ndothelial cells in response to a variety of injurious stimuli and recently have been shown to be inc

228 The biochemical pathways activated by these injurious stimuli are described herein and will serve as

229 fluence the sensitivity of neuronal cells to injurious stimuli by modulating calcium-dependent apopto

230 ng system is a point of convergence at which injurious stimuli can trigger and amplify both acute inf

231 Sublethal injurious stimuli in neurons induce transient increases

232 phagocytosing macrophage (Mphis) that clear injurious stimuli leading to resolution and tissue homeo

233 pass (CP/CPB) subjects myocardium to complex injurious stimuli that can result in cardiomyocyte and v

234 ith cystic fibrosis with hypersensitivity to injurious stimuli, biofilm PsaDM activated p38alpha MAPK

235 ng the BSCB and/or removing the BSCB-derived injurious stimuli, we now identify that accumulation of

236 ndothelial cell (EC) hyperpermeability after injurious stimuli.

237 ithelial response to ligands, pathogens, and injurious stimuli.

238 nsmigration, and enhance resistance to local injurious stimuli.

239 of neuronal apoptosis following a variety of injurious stimuli.

240 rticipate in morphogenesis and to respond to injurious stimuli.

241 as an adaptive response to a wide variety of injurious stimuli.

242 to penetrating microbes, noxious agents, and injurious stimuli.

243 roprotective phenomenon by which a sublethal injurious stimulus renders the brain resistant to a subs

244 foundly shift the host response to a defined injurious stimulus, in part by augmenting delivery of ne

245 in critically ill patients in response to an injurious stimulus.

246 zo-mediated cartilage mechanotransduction of injurious strains.

247 in kinase p38 mediates cellular responses to injurious stress and immune signaling.

248 Labeling after removal of injurious stress revealed significantly fewer injured ce

249 es acute inflammation in the adult lung, and injurious styles of mechanical ventilation can result in

250 defects, hearing loss and autistic and self-injurious tendencies also frequently occur.

251 nic inflammation that is characterized by an injurious Th2 immune response.

252 and chronic hyperglycaemia appear to be more injurious than previously suspected, whereas a history o

253 ors examined a new method that measures self-injurious thoughts by using individuals' reaction times

254 The assessment of self-injurious thoughts has been limited by a reliance on wha

255 Test as a performance-based measure of self-injurious thoughts.

256 crobial therapy, mechanical ventilation with injurious tidal volumes, hospital-acquired aspiration, a

257 eyes, although useless, could be in any way injurious to animals living in darkness, I attribute the

258 ndicating that upregulated COX-2 activity is injurious to neurons.

259 iolence; fighting and fleeing actions can be injurious to patients as well as bed partners.

260 patic accumulation; NSAIDs may be especially injurious to patients with alpha(1)-AT deficiency, possi

261 PF may be difficult and potentially injurious to the donor kidney, especially in grafts with

262 controlled secretion of neutrophil cargos is injurious to the host and should be closely regulated.

263 Anti-OVA IgG is not directly injurious to the islets but rather enhances cross-presen

264 Mechanical ventilation is injurious to the lung.

265 ical ventilation with large tidal volumes is injurious to the lung.

266 ence that poor ventilatory technique that is injurious to the lungs can propagate the systemic inflam

267 hanisms that can diminish lapses in research injurious to the public's trust.

268 protective against infection, these NETs are injurious to tissue.

269 the with large tidal volumes and potentially injurious transpulmonary pressure swings.

270 responses throughout the body, resulting in injurious vascular leakage and organ inflammation.

271 The exposure to potentially injurious ventilation decreased after the intervention f

272 lung injury induced by whole-lung lavage and injurious ventilation in four rabbits.

273 Prone positioning was protective against injurious ventilation in rats.

274 induced with saline lung lavage followed by injurious ventilation in supine position.

275 Injurious ventilation induces MAPK in an MKP-1-dependent

276 nd transient, whereas in lungs labeled after injurious ventilation propidium iodide fluorescence iden

277 ially serves as a basis upon which minimally injurious ventilation strategies might be developed.

278 In lungs labeled during injurious ventilation, propidium iodide fluorescence ide

279 ere perfused ex vivo, either during or after injurious ventilation, with a solution containing the me

280 al target for modulating regional effects of injurious ventilation.

281 m iodide was perfused either during or after injurious ventilation.

282 peated saline lavages followed by 2 hours of injurious ventilation.

283 ated patients accurately detects potentially injurious ventilator settings and is able to influence b

284 e text paging notification about potentially injurious ventilator settings.

285 ation of bedside providers about potentially injurious ventilator settings.

286 Both injurious ventilatory protocols developed comparable lev

287 Biotrauma due to injurious ventilatory strategies can lead to the release

288 In the multivariable analysis, baseline injurious violence (hazard ratio=4.02), recent violent v

289 aled simultaneous strong effects of baseline injurious violence and recent violent victimization on f

290 For participants with no history of injurious violence at study entry, baseline noninjurious

291 ts and, separately, for participants with no injurious violence at study entry.

292 ven participants (5.4%) reported engaging in injurious violence during follow-up, and 119 (8.3%) repo

293 inal multivariable analysis of predictors of injurious violence in a large cohort of patients with sc

294 he strength of their association with future injurious violence were similar to those for all partici

295 Proportional hazards models of time to first injurious violence were used to generate bivariable and

296 hosis or depression, significantly predicted injurious violence.

297 zard ratio=1.39) were associated with future injurious violence.

298 e and recent violent victimization on future injurious violent behavior.

299 ATP levels were maintained during hypoxia to injurious when reoxygenation followed glucose and ATP de

300 ervice listed 201 species of salamanders as "injurious wildlife" under the Lacey Act (18 U.S.C. secti