ライフサイエンスコーパス: innate immune mechanism

1 CD40 inhibits HCV replication by a novel, innate immune mechanism.

2 ated by both TLR2-dependent and -independent innate immune mechanisms.

3 ed in wound healing, angiogenesis, and other innate immune mechanisms.

4 le sclerosis, suggest a significant role for innate immune mechanisms.

5 ssion advantage through adaptation to resist innate immune mechanisms.

6 on by metazoans of bacterial cell-autonomous innate immune mechanisms.

7 CauEVs) activate murine phagocytes, boosting innate immune mechanisms.

8 ment is rigorously maintained by a number of innate immune mechanisms.

9 ion, energy metabolism, gene expression, and innate immune mechanisms.

10 om the adaptive immune response more towards innate immune mechanisms.

11 fter depletion of T lymphocytes, implicating innate immune mechanisms.

12 required for disease, little is known about innate immune mechanisms.

13 clearance of B. burgdorferi, presumably via innate immune mechanisms.

14 he graft is triggered by antigen-independent innate immune mechanisms.

15 of gamma interferon via antigen-specific and innate immune mechanisms.

16 tis, providing support for a model involving innate immune mechanisms.

17 e also able to control pathology mediated by innate immune mechanisms.

18 rather than by the activation of nonspecific innate immune mechanisms.

19 dothelial cells through the participation of innate immune mechanisms.

20 he effect of different H. pylori products on innate immune mechanisms.

21 ptors (TLRs), enriching our understanding of innate immune mechanisms across life forms and underscor

22 tudy reveals the gut complement system as an innate immune mechanism acting as a vigilant sentinel th

23 and type 1 interferon (T1-IFN) signaling are innate immune mechanisms activated upon viral infection.

24 Iron sequestration is a recognized innate immune mechanism against invading pathogens media

25 n of type I interferons (IFN-I) is a crucial innate immune mechanism against viral infections.

26 Although bacterial innate immune mechanisms against phage abound, the only

27 Innate immune mechanisms against Pneumocystis carinii, a

28 arva Aspergillus infection model to identify innate immune mechanisms altered by glucocorticoid treat

29 efine viral response proteinuria (VRP) as an innate immune mechanism and co-activation of podocyte in

30 asome in response to danger signals is a key innate immune mechanism and results in the production of

31 sponses suggests that early, cytokine-driven innate immune mechanisms and CD8(+) T cell-mediated resp

32 s in the regulation of hematopoiesis through innate immune mechanisms and illustrate the expansive ce

33 ve infection, HIV-1 must counteract cellular innate immune mechanisms and redirect cellular processes

34 ns directly to the cytosol of cells, inhibit innate immune mechanisms, and prevent bacterial clearanc

35 T3SS effectors target host innate immune mechanisms, and T3SS-defective mutants are

36 mmune responses, the effects of pathogens on innate immune mechanisms, and the potential impact of vi

37 Our results show that innate immune mechanisms are activated immediately after

38 Conversely, innate immune mechanisms are also central to noninflamma

39 Innate immune mechanisms are crucial in defense against

40 n is associated with depressive symptoms and innate immune mechanisms are likely causal in some cases

41 Innate immune mechanisms are not so effective against bi

42 Intrinsic innate immune mechanisms are the first line of defense a

43 Flagellin made L. pneumophila vulnerable to innate immune mechanisms because Naip5+ macrophages rest

44 mited numbers of autoreactive T cells, while innate immune mechanisms become sufficient to provoke di

45 These studies indicate that innate immune mechanisms bridge to and enhance the adapt

46 These studies define an innate immune mechanism by which pathogenic fungi regula

47 Pathogenic Yersinia species neutralize innate immune mechanisms by injecting type three secreti

48 The data also delineate innate immune mechanisms by which TLI/ATS/CTX conditioni

49 In addition to its established role in innate immune mechanisms, complement component C3 is als

50 ioxygenase (IDO) is believed to be the major innate immune mechanism controlling C. trachomatis infec

51 However, the innate immune mechanisms controlling sunburn development

52 The mammalian host has a number of innate immune mechanisms designed to limit the spread of

53 lled mononuclear phagocyte activity, yet the innate immune mechanisms driving HLH pathogenesis remain

54 ammation have been observed, but fundamental innate immune mechanisms driving pathology during pathog

55 such inflammatory disease, and the specific innate immune mechanisms driving pathology in this conte

56 adenitis suppurativa is complex and includes innate immune mechanisms (eg, macrophages, neutrophils,

57 stablish a granzyme- and granulysin-mediated innate immune mechanism exerted by gammadelta T cells to

58 lthy volunteers, demonstrating that impaired innate immune mechanisms following DEP exposure are also

59 l, these findings identify a cell-autonomous innate immune mechanism for autophagy activation to clea

60 Local inflammation is a major innate immune mechanism for containing and destroying mi

61 d effective neutrophil function are critical innate immune mechanisms for bacterial clearance.

62 Because of this long history, innate immune mechanisms found in modern eukaryotic orga

63 nsects and other arthropods, which have only innate immune mechanisms, four main immune-specific modu

64 Here, we report a novel innate immune mechanism functioning against respiratory

65 Innate immune mechanisms further perpetuate liver injury

66 ghlight how a comprehensive understanding of innate immune mechanisms has been crucial in the fight a

67 Genes involved in both adaptive and innate immune mechanisms have been identified, notably i

68 o and counteract these elements, a number of innate immune mechanisms have evolved that can lead to l

69 ive immunity captured most of the attention, innate immune mechanisms have now become central to our

70 Recent findings highlight the importance of innate immune mechanisms in disease pathogenesis.

71 on and Toll pathway activation are essential innate immune mechanisms in insects, which result in the

72 e hydroxylase (Th) homeostasis and activates innate immune mechanisms in the brain and provide eviden

73 ivates CARD4/NOD1 transcription and regulate innate immune mechanisms in the condition of intestinal

74 for the first time identify a major role for innate immune mechanisms in the induction and persistenc

75 article focuses on the role of adaptive and innate immune mechanisms in the pathogenesis of celiac d

76 re is increasing evidence for involvement of innate immune mechanisms in the pathogenesis of idiopath

77 he investigation of evolutionarily conserved innate immune mechanisms, including NF-kappaB-dependent

78 a new dimension to our understanding of the innate immune mechanisms involved in controlling intrama

79 from this study provide more details on the innate immune mechanisms involved in DNA vaccination and

80 ghts into the interplay between adaptive and innate immune mechanisms involved in HIV-1 immunity and

81 A detailed understanding of the innate immune mechanisms involved in restricting SARS-Co

82 Indirect evidence suggests that innate immune mechanisms involving alveolar macrophages

83 fully develop or be greatly enhanced through innate immune mechanisms involving IL-33, natural helper

84 Signaling via innate immune mechanisms is considered pivotal for T cel

85 ng the balance between positive and negative innate immune mechanisms is crucial for maintaining home

86 Innate immune mechanisms leading to liver injury subsequ

87 Stimulation of multiple innate immune mechanisms may prove a generalizable prope

88 and postulates that CS therapy, by reducing innate immune mechanisms, may promote C. albicans coloni

89 The findings establish a candidate innate immune mechanism of action for a human autoimmuni

90 ment system not only represents an effective innate immune mechanism of host defense to eradicate mic

91 nt mice, revealing a previously unrecognized innate immune mechanism of intestinal tissue protection.

92 The innate immune mechanisms of host cells are diverse in na

93 Although most attention has been focused on innate immune mechanisms of inflammatory carcinogenesis,

94 This review focuses on molecular and innate immune mechanisms of ischemia-reperfusion injury

95 In this review, we focus on innate immune mechanisms of platelet activation, platele

96 at styelin D plays a significant role in the innate immune mechanisms of S. clava.

97 Together, our work identifies innate immune mechanisms of vector sensing in the CNS th

98 Rather, innate immune mechanisms or an intact epithelial barrier

99 emonstrate that flagellin induces additional innate immune mechanisms over those induced by VSV alone

100 m where it has to avoid being killed by host innate immune mechanisms, particularly the complement sy

101 Both adaptive and innate immune mechanisms provide protection from infecti

102 n, indicating restraint of infection through innate immune mechanisms rather than entry.

103 ghts enhance our understanding of Drosophila innate immune mechanisms, reflecting the evolutionary co

104 plex interactions between the microbiota and innate immune mechanisms, such as the inflammasome-media

105 These findings highlight a key innate immune mechanism that contributes to control of a

106 IDO1 is a lung-specific innate immune mechanism that controls pulmonary Francise

107 In summary, we identified an innate immune mechanism that impairs the activity of a c

108 opolysaccharide (LPS)-induced chemotaxis, an innate immune mechanism that is particularly crucial whe

109 The findings demonstrate a highly regulated innate immune mechanism that potentially rapidly tackles

110 largely unknown.Objectives: To identify the innate immune mechanism that promotes platelet-neutrophi

111 Complement is an essential innate immune mechanism that recognizes and eradicates m

112 s, it remains essential to better understand innate immune mechanisms that can inhibit the virus.

113 clear, however, whether host species possess innate immune mechanisms that can neutralize pore-formin

114 Deciphering the role of innate immune mechanisms that confer tolerance to ischem

115 Our work uncovers vector-induced innate immune mechanisms that contribute to cell death.

116 position regulates colitis severity, yet the innate immune mechanisms that control commensal communit

117 nd uncover an intricate relationship between innate immune mechanisms that control response to self a

118 As such, understanding the innate immune mechanisms that enable this T cell respons

119 In this review, we discuss multiple innate immune mechanisms that have evolved to modify the

120 We discuss the acquired and innate immune mechanisms that may be behind the associat

121 To define the innate immune mechanisms that mediate control of RRV inf

122 Understanding the early innate immune mechanisms that participate in the develop

123 However, the innate immune mechanisms that promote natural antitumor

124 t studies have advanced our understanding of innate immune mechanisms that protect the airways and ma

125 a vascular watershed following activation of innate immune mechanisms that provoke hypoxia, and super

126 ction and epithelial barrier repair, yet the innate immune mechanisms that selectively drive GC funct

127 Here, we discuss the innate immune mechanisms that sense coronaviruses, with

128 hese diseases, we discuss recent advances in innate-immune mechanisms that have been demonstrated to

129 cGAS-STING pathway constitutes a widespread innate immune mechanism to monitor cellular damage and m

130 (piRNAs) act in an evolutionarily conserved innate immune mechanism to provide essential protection

131 cell-mediated immune responses can regulate innate immune mechanisms to defend against microbial pat

132 anatomic sites of the body employ different innate immune mechanisms to defend against potential inf

133 discuss how SARS-CoV-2 evades key protective innate immune mechanisms to enhance its virulence and pa

134 ow the system integrates with more primitive innate immune mechanisms to maintain immune homeostasis,

135 analysis of the transition from reliance on innate immune mechanisms to the appearance of adaptive i

136 of this review is to highlight the multiple innate immune mechanisms triggered by protease allergens

137 Defining the innate immune mechanisms underlying the establishment of

138 epresent a new resource in understanding the innate immune mechanisms underlying the link between COP

139 ntrast, lactoferrin, an effector molecule of innate immune mechanisms, was unable to prevent fungal b

140 Rather, HD6 possesses a unique innate immune mechanism whereby it self-assembles into o

141 These data indicate that an innate immune mechanism which is present from birth i.e.

142 Little is known about innate immune mechanisms within the cardiac myocyte that

143 hile simultaneously inhibiting apoptosis and innate immune mechanisms within the macrophage, permitti