ライフサイエンスコーパス: innate lymphocyte

1 l-specific phenotype did not extend to other innate lymphocytes.

2 lls (DCs) directed IFN-gamma production from innate lymphocytes.

3 that bear striking similarity to lineages of innate lymphocytes.

4 scapes of these modifications are unknown in innate lymphocytes.

5 on CD34(+) cell differentiation into CD56(+) innate lymphocytes.

6 developments in understanding the biology of innate lymphocytes.

7 viously considered to represent short-lived, innate lymphocytes.

8 ring the dynamic response of these cytolytic innate lymphocytes.

9 lved in the generation and survival of these innate lymphocytes.

10 uals and psoriasis patients are CD3-negative innate lymphocytes.

11 ining role of PLZF in the differentiation of innate lymphocytes.

12 velopment of other mucosal tissue-associated innate lymphocytes.

13 ation of gammadelta T cells and RORgammat(+) innate lymphocytes.

14 phenotypic and functional characteristics of innate lymphocytes.

15 However, the role of C5a in innate lymphocyte activation during sepsis remains elusi

16 h counts of neutrophils (innate), monocytes (innate), lymphocytes (adaptive), and the neutrophil-to-l

17 report that depletion of NK cells, a type of innate lymphocytes, alleviates neuroinflammation, stimul

18 We now appreciate that innate lymphocytes also possess memory properties akin t

19 re, our findings establish that RORgammat(+) innate lymphocytes and gammadelta T cells are necessary

20 et al. examines interactions between group 2 innate lymphocytes and gastric microbes that enhance IgA

21 is interaction in turn expands and activates innate lymphocytes and initiates adaptive T cell immunit

22 prewired responses involving myeloid cells, innate lymphocytes and innate-like adaptive lymphocytes

23 ancer immunity is either pre-wired, in which innate lymphocytes and innate-like T cells are directly

24 Expression of SLC11A1 in innate lymphocytes and its role in augmenting their acti

25 al skin is characterized by the expansion of innate lymphocytes and T cells expressing CD2, an essent

26 t trigger clonal or clonal-like expansion in innate lymphocytes, and highlight recent studies that sh

27 s, loss of antigen-presenting cells, loss of innate lymphocytes, and possible alterations to the comp

28 of effector function diversification in all innate lymphocytes, and the kinetics of immune responses

29 ge with characteristics of both adaptive and innate lymphocytes, and they recognize glycolipids prese

30 Fast innate lymphocytes are active within hours after infecti

31 gammadelta T cells are considered innate lymphocytes because of their non-MHC restricted a

32 yd T cells are considered innate lymphocytes because of their non-MHC restricted a

33 tomic analyses show that GPR25 is induced on innate lymphocytes before emigration to the periphery, a

34 Natural Killer (NK) cells are innate lymphocytes best known for their role against vir

35 Here, we review advances in understanding of innate lymphocyte biology with a focus on skin disease a

36 nate lymphoid cells (ILC1s) are heterogenous innate lymphocytes broadly defined in mice as Lin(-)NK1.

37 type 2 immune responses mediated not only by innate lymphocytes but also by myeloid-derived cells.

38 ls, including T-helper (Th) cell subsets and innate lymphocytes, but acts only on non-hematopoietic s

39 Natural killer (NK) cells are innate lymphocytes capable of "adaptive" responses after

40 NK cells are innate lymphocytes capable of eliciting an innate immune

41 NK cells are innate lymphocytes capable of generating "adaptive" resp

42 While NK cells are innate lymphocytes capable of recognizing injured cells,

43 es conventional CD8(+) thymocytes to acquire innate lymphocyte characteristics.

44 Type 1 innate lymphocytes comprise two developmentally divergen

45 results suggest that IL-2-dependent adaptive-innate lymphocyte cross talk tunes NK cell reactivity an

46 rstanding of regulatory mechanisms of thymic innate lymphocyte development.

47 rn, ensures on-demand production of IL-22 by innate lymphocytes directly regulating components of the

48 Transcriptomic analysis of innate lymphocytes during endotoxemia suggested that NKT

49 Although circulating adaptive and innate lymphocyte effector responses are required for ef

50 , the potential for an effective response by innate lymphocyte effectors such as NK and yd T cells th

51 ant NKT (iNKT) cells are glycolipid-specific innate lymphocytes emerging as critical players in the i

52 Innate lymphocytes encompass a diverse array of phenotyp

53 Natural killer (NK) cells, which are innate lymphocytes endowed with potent cytotoxic activit

54 by ILC production of IL-17A, indicating that innate lymphocytes engage in a positive-feedback loop wi

55 ngs provide a powerful resource for studying innate lymphocyte epigenetic regulation and decode the r

56 CD2(+) cells were mainly innate lymphocytes expressing the NK cell marker, CD56,

57 ma secretion by the strategically positioned innate lymphocytes, fostering antimicrobial resistance i

58 of pathogens as environmental cues to modify innate lymphocyte functionalities.

59 Innate lymphocytes (gammadelta T cells, natural killer c

60 thology of demyelinating diseases.IMPORTANCE Innate lymphocytes have plasticity and can change functi

61 e findings highlight the adaptive control of innate lymphocyte homeostasis.

62 1A (Tnfsf15) costimulates T cells and type 2 innate lymphocytes (ILC2) through its receptor DR3 (Tnfr

63 Group 2 innate lymphocytes (ILC2s) are prevalent in small intest

64 Here, we describe type 2 innate lymphocytes (ILC2s) as a novel cell type resident

65 Pulmonary type 2 innate lymphocytes (ILC2s) show sex dimorphism in number

66 n innate immune response dominated by type 2 innate lymphocytes (ILC2s).

67 All type 1 innate lymphocytes (ILCs) express the transcription fact

68 function of human natural killer (NK) cells, innate lymphocytes important for anti-viral and tumor im

69 Natural killer (NK) cells are innate lymphocytes important for early host defense agai

70 NK cells are innate lymphocytes important for host defense against vi

71 ay account for inconsistencies in studies of innate lymphocytes in different animal models.

72 e a unique IL-17 signature and activation of innate lymphocytes in FPIES.

73 Impaired thymic development of PLZF(+) innate lymphocytes in germ-free (GF) neonatal mice is re

74 ing that MAIT cells play a unique role among innate lymphocytes in protective immunity against bacter

75 ere used to explore the role of adaptive and innate lymphocytes in the flaky skin phenotype.

76 ocation-specific features, shared with other innate lymphocytes in the lung, possibly consistent with

77 Innate lymphocytes, including both natural killer cells

78 al mechanisms controlling the development of innate lymphocytes, including natural killer cells and t

79 explore the key features of immune memory in innate lymphocytes, including quantity, quality, and loc

80 resistance of C3H/HeJ or CBA mice through an innate, lymphocyte-independent mechanism, but it had no

81 We investigated the contribution of innate lymphocytes, innate lymphoid cells (ILCs), and na

82 prompted a provisional classification of all innate lymphocytes into groups 1, 2 and 3 solely on the

83 landscape and the noncoding genome of these innate lymphocytes is allowing us to better understand t

84 Natural killer (NK) cells are innate lymphocytes known for their ability to kill infec

85 tudy was to investigate gamma/delta T cells, innate lymphocytes known to be involved in tissue repair

86 A role for T reg cells in the homeostasis of innate lymphocyte lineages remained unknown.

87 programs during the development of multiple innate lymphocyte lineages, including natural killer T c

88 discovery of an unprecedented complexity in innate lymphocyte lineages, now collectively referred to

89 oadest immunomodulation, inducing changes in innate lymphocytes, macrophages, and RORgamma(+) regulat

90 Innate lymphocytes maintain tissue homeostasis at mucosa

91 Recent studies have shown that innate lymphocytes--natural killer (NK), natural killer

92 growing evidence for the clonal expansion of innate lymphocytes, particularly in the context of patho

93 ction and support the possibility that these innate lymphocytes play a role in controlling the malign

94 Here we describe an innate lymphocyte population, iCD8alpha cells, character

95 lymphocytes, which softens the margins with innate lymphocyte populations and allows investigation o

96 In contrast, oligoclonal innate lymphocyte populations are efficiently expanded t

97 Innate lymphocyte populations are emerging as key effect

98 erm glycan-induced protection is mediated by innate lymphocyte populations including TCR-gammadelta+

99 Innate lymphocyte populations play a central role in con

100 has been implicated in the function of novel innate lymphocyte populations that regulate both protect

101 m of protective trained immunity mediated by innate lymphocyte populations.

102 cells (glycolipid-specific, CD1d-restricted innate lymphocytes) provide both cognate (direct) and no

103 we explore emerging evidence that activated innate lymphocytes relocate and establish themselves in

104 ndent negative regulatory factor that shapes innate lymphocyte responses to alarmins and neuropeptide

105 ranscription responsible for differentiating innate lymphocyte responses towards a memory fate.

106 the concerted and nonredundant action of two innate lymphocyte subpopulations, conventional natural k

107 ive temporally controlled fate mapping of an innate lymphocyte subset with notable nuances as compare

108 ly to MCMV defense, revealing that these two innate lymphocyte subsets function together to fine-tune

109 e in the function and development of several innate lymphocyte subsets, is also important for the mye

110 They more closely resemble other lineages of innate lymphocytes such as B-1 B cells, gammadelta T cel

111 of immune cells, particularly enriched with innate lymphocytes such as NK cells, NKT cells, and gamm

112 In contrast, innate lymphocytes, such as natural killer (NK) cells, a

113 ells, to include NH cells as another type of innate lymphocyte that derives from bone marrow lymphoid

114 infections, resulting in an expanded pool of innate lymphocytes that are able to participate in early

115 Natural killer (NK) cells are innate lymphocytes that are considered central players i

116 nown role in activation of a large subset of innate lymphocytes that are critical sources of IFN-gamm

117 (NKT) cells are distinct glycolipid reactive innate lymphocytes that are implicated in the resistance

118 Natural killer (NK) cells are innate lymphocytes that are thought to kill cells that d

119 NK cells are short-lived innate lymphocytes that can mediate antigen-independent

120 Natural killer (NK) cells are innate lymphocytes that can regulate adaptive immune res

121 Group 2 innate lymphoid cells (ILC2) are innate lymphocytes that confer protective type 2 immunit

122 Natural killer T (NKT) cells are innate lymphocytes that differentiate into NKT1, NKT2, a

123 Natural killer (NK) cells are innate lymphocytes that eliminate virus-infected and can

124 Natural killer (NK) cells are innate lymphocytes that exhibit adaptive features, such

125 Natural killer (NK) cells are innate lymphocytes that exhibit adaptive traits particul

126 Natural killer (NK) cells are innate lymphocytes that exhibit many features of adaptiv

127 crosstalk between inflammatory monocytes and innate lymphocytes that is mediated by TNF and IL-17A.

128 NK cells are innate lymphocytes that mediate early host defense again

129 gammadelta T cells (gammadeltaT17 cells) are innate lymphocytes that participate in type 3 immune res

130 Natural killer (NK) cells are innate lymphocytes that play a critical role in host def

131 Natural killer (NK) cells are innate lymphocytes that play an important role against v

132 ells are CD1d-restricted glycolipid reactive innate lymphocytes that play an important role in protec

133 NK cells are innate lymphocytes that play an integral role in tumor r

134 Natural killer cells are innate lymphocytes that play vital roles in a diverse ra

135 Natural killer (NK) cells are innate lymphocytes that possess traits of adaptive immun

136 Natural killer (NK) cells are innate lymphocytes that possess traits of adaptive immun

137 Natural killer (NK) cells are innate lymphocytes that provide critical host defense ag

138 Natural killer (NK) cells are innate lymphocytes that provide cytokines critical for e

139 Natural killer (NK) cells are innate lymphocytes that provide early host defense again

140 inducer (LTi)-like cells are tissue resident innate lymphocytes that rapidly secrete cytokines that p

141 Natural killer (NK) cells are innate lymphocytes that recognize and lyse virally infec

142 Invariant NKT cells (iNKT cells) are innate lymphocytes that recognize lipid-derived Ags pres

143 Invariant NKT (iNKT) cells are innate lymphocytes that respond to glycolipids presented

144 Natural killer (NK) cells are innate lymphocytes that target virus-infected and tumor

145 Here, we have identified a population of innate lymphocytes that we term tissue-resident memory-l

146 focuses on the response of myeloid cells and innate lymphocytes to dietary cues, their cross-regulato

147 f mucosal immunity, integrating signals from innate lymphocytes to induce optimal epithelial Stat3 ac

148 of numerous genes, including genes encoding innate lymphocyte transcription factors, specifically in

149 te previously unknown migratory behaviors of innate lymphocytes undergoing lineage differentiation re

150 h clonally expressed antigen receptors, from innate lymphocytes, which carry out more rapid responses

151 ration of fetal antigen presenting cells and innate lymphocytes, which could have implications for gl

152 mmarize the evidence for clonal expansion in innate lymphocytes, which has primarily been observed in

153 ypic cell-to-cell communication among mobile innate lymphocytes, which promotes functional synergy wi

154 ediated by RAG endow developing adaptive and innate lymphocytes with a cellular "fitness" that safegu

155 l killer (NK) cells are highly heterogeneous innate lymphocytes with a diverse repertoire of phenotyp

156 Natural Killer cells are innate lymphocytes with central roles in immunosurveilla

157 NK cells are a heterogenous population of innate lymphocytes with diverse functional attributes cr

158 ) cells are cytotoxic and cytokine-producing innate lymphocytes with established roles in antiviral a

159 Natural killer (NK) cells are cytotoxic innate lymphocytes with key roles in host protection aga

160 Natural killer (NK) cells are innate lymphocytes with notable activity against a broad

161 Natural killer (NK) cells are innate lymphocytes with potent cytotoxic activity.

162 NK cells are innate lymphocytes with protective functions against vir