ライフサイエンスコーパス: inner leaflet

1 ral to the pore that faces the lipid bilayer inner leaflet.

2 drug pathway at the level of the membrane's inner leaflet.

3 eracts with negatively charged lipids in the inner leaflet.

4 outer leaflet and phospholipids (PLs) at the inner leaflet.

5 leoyl-phosphatidylethanolamine (POPE) in the inner leaflet.

6 PSs are needed for lo phase induction in the inner leaflet.

7 eaflet, pyranine detects its movement to the inner leaflet.

8 outer leaflet and phospholipids (PLs) in the inner leaflet.

9 d composition similar to the plasma membrane inner leaflet.

10 lipid mixture mimicking the plasma membrane inner leaflet.

11 1with the phospholipids of the cell membrane inner leaflet.

12 with phosphatidylserine (PS) confined to the inner leaflet.

13 ating the composition of the plasma membrane inner leaflet.

14 the lipid bilayer, which is confined to its inner leaflet.

15 phosphocholine alone has been imaged on the inner leaflet.

16 et packing but also on the properties of the inner leaflet.

17 atidylserine (PS) exclusively present in the inner leaflet.

18 stablishes a peripheral association with the inner leaflet.

19 ch was passively distributed with 80% in the inner leaflet.

20 ibrate across SV to approximately 20% in the inner leaflet.

21 ion that interacts with the membrane bilayer inner leaflet.

22 y to anionic phospholipids in the membrane's inner leaflet.

23 n and the negatively charged plasma membrane inner leaflet.

24 n the outer leaflet and phospholipids in the inner leaflet.

25 n the outer leaflet and phospholipids in the inner leaflet.

26 n and oligomerization on the plasma membrane inner leaflet.

27 s, whereas PS is typically found only on the inner leaflet.

28 ositides show preferential clustering in the inner leaflet.

29 tidylinositol 4,5-bisphophate (PIP2), in the inner leaflet.

30 ed different lipid mixtures in its outer and inner leaflets.

31 nto proximity, and then fuse their outer and inner leaflets.

32 ) in their outer leaflets, and DOPC in their inner leaflets.

33 sphingomyelin (SM) with cholesterol and the inner leaflet a mixture of stearoyl-oleoyl-phosphatidyls

34 different number of lipids in the outer and inner leaflet, a difference in transmembrane headgroup h

35 ) sequential molecular interactions with the inner leaflet along with Tec kinase-dependent tyrosine p

36 cyte ghosts; membrane fusion is inhibited by inner-leaflet amphiphiles of positive intrinsic curvatur

37 ng sites were identified on UraA: two in the inner leaflet and a single site in the outer leaflet.

38 4,5)P(2)-mediated recruitment of FGF2 at the inner leaflet and heparan sulfates capturing FGF2 at the

39 The first arises from the inner leaflet and is coordinated by hydrophobic residues

40 uter membrane (OM) with phospholipids in its inner leaflet and lipopolysaccharides (LPS) in its outer

41 bacteria is composed of phospholipids in the inner leaflet and lipopolysaccharides (LPS) in the outer

42 asymmetry, with phospholipids comprising the inner leaflet and lipopolysaccharides comprising the out

43 ymmetric bilayer having phospholipids in the inner leaflet and lipopolysaccharides in the outer leafl

44 living cell membranes, communication between inner leaflet and outer leaflet, membrane adhesion, and

45 h a 5 A-wide lateral opening in the membrane inner leaflet and physically blocks ion passage.

46 s containing phosphatidylcholine (PC) in the inner leaflet and sphingomyelin (SM) in the outer leafle

47 bilayer structure with phospholipids in the inner leaflet and the complex glycolipid lipopolysacchar

48 o peptide bonds are hydrolyzed: one near the inner leaflet and the other in the middle of the transme

49 tidylserine (restricted to the cell membrane inner leaflet) and cardiolipin (present in the inner and

50 hosphatidylinositol-4,5-bisphosphate) in the inner leaflet, and GM3 (monosialodihexosylganglioside) i

51 rdinarily sequestered in the plasma membrane inner leaflet, appears in the outer leaflet during apopt

52 leaflets of the bilayers are mixed, but the inner leaflets are not.

53 a more compact E. coli MscL at the membrane inner-leaflet, as a consequence of a rotated TM2 helix.

54 and other lipids normally sequestered to the inner leaflet become exposed at the cell surface.

55 l chains capable of interdigitating into the inner leaflet, both outer- and inner-leaflet Lo domains

56 udinal diffusion of TMPs and the IMPs of the inner leaflet but not of the IMPs of the outer leaflet.

57 ne (P-C6-NBD-PC) to approximately 50% in the inner leaflet by a protein-mediated process.

58 , and RcsF was thought to be tethered to the inner leaflet by its lipidated N terminus, raising the q

59 Therefore, spontaneous curvature of inner leaflets can affect formation and enlargement of f

60 d by selective reacylation of lyso-PE in the inner leaflet, can account for the compositional and arc

61 OS is unique as it achieves nearly universal inner leaflet cellular activity to enable the exit of pa

62 phase domains are induced in all quaternary inner leaflet combinations composed of PCs, PEs, PSs, an

63 used to examine co-redistributions of these inner leaflet components with IgE-Fc(epsilon)RI and oute

64 do not detectably coredistribute with these inner leaflet components.

65 bilayer covering the cell surface, with its inner leaflet composed mainly of the aforementioned none

66 ymmetric vesicles was not destabilized by an inner leaflet composed of DOPE and POPS.

67 similar number of hydrocarbon chains as the inner leaflet composed of mycolic acids covalently linke

68 had little effect upon lateral diffusion in inner leaflets composed of dioleoyl PC (i.e., diffusion

69 cyl chains, also greatly reduce diffusion of inner leaflets composed of dioleoyl PC, indicative of st

70 but did greatly reduce lateral diffusion in inner leaflets composed of PC with one saturated and one

71 ions of PS that are representative of the PM inner leaflet content.

72 hemifusion of the outer leaflet followed by inner leaflet (core) fusion.

73 mount of galactosylceramide localized in the inner leaflet decreased from 70% in pure 1-palmitoyl-2-o

74 40A away, and suggest how lipids and bilayer inner leaflet deformations may gate the channel.

75 transverse diffusion of TMPs and IMPs of the inner leaflet, depending on the strength of the associat

76 s unknown but may be due to the induction of inner leaflet domains by the outer leaflet.

77 ribution of total mass from the outer to the inner leaflet during the fusion process could be detecte

78 which the outer leaflets are fused while the inner leaflets engage in a hemifusion diaphragm (HD).

79 is asymmetry, the net-negative charge at the inner leaflet exceeds that at the outer leaflet.

80 difies the diffusion of TMPs and IMPs of the inner leaflet from normal to confined-hop diffusion.

81 en the hardened outer leaflet and the softer inner leaflet generates bending stresses in the bilayer,

82 s PtdSer increases the charge density of the inner leaflet, generating foci of enhanced charge and cu

83 ot reflected in increased lipid order in the inner leaflet, i.e., there was no detectable coupling be

84 g helix (TM) and another that penetrates the inner leaflet (IM).

85 holipids were translocated from the outer to inner leaflet in a matter of minutes and reached an equi

86 A5 retains negatively charged lipids in the inner leaflet in an injured cell.

87 between the physical states of the outer and inner leaflets in these asymmetric LUVs becomes very wea

88 dues are located either in the region of the inner leaflet, in the center, as well as in the periplas

89 The inner leaflet is composed predominantly of zwitterionic

90 Critical concentrations at which the inner leaflet is disrupted were determined for each olig

91 composed of lipopolysaccharide (LPS) and the inner leaflet is formed by glycerophospholipid (GPL).

92 cognize membrane rafts, if they exist in the inner leaflet, is unknown.

93 Specifically, inner leaflet lateral mobility of globular actin-support

94 However, inner leaflet lipid markers are able to diffuse through

95 rs with apposed leaflets composed of typical inner leaflet lipid mixtures.

96 xchange into the outer leaflet increased the inner leaflet lipid order, suggesting significant interl

97 hosphatydic acid (DOPA), was employed as the inner leaflet lipid to coat the nano-size CaP cores, whi

98 synaptobrevin C-terminus from the vesicle's inner-leaflet lipid headgroups and pulled it deeper into

99 ntent release and dequenching coincides with inner-leaflet lipid mixing within 10 ms.

100 ecific interaction between an amino acid and inner-leaflet lipid that governs the gating transformati

101 recovery after photobleaching indicated that inner leaflet lipids are able to move through DC-SIGN mi

102 that in vesicles containing either only the inner leaflet lipids from the asymmetric vesicles or onl

103 from those in the bulk membrane, whereas the inner leaflet lipids were quite similar to those found i

104 ting into the inner leaflet, both outer- and inner-leaflet Lo domains were depleted, to a similar ext

105 aturated fluorescent lipid (NBD-DPPE), while inner-leaflet Lo domains were not.

106 Simultaneously, at the inner leaflet, long acyl-chain-containing phosphatidylse

107 a fusion-committed second intermediate; (4) inner leaflet mixing on a time scale of ca. 150 s; and (

108 Inner leaflet mixing, which has never before been shown

109 ays that monitor both total lipid mixing and inner leaflet mixing.

110 Evidently, at the instant of inner-leaflet mixing, flattening of the vesicle increase

111 It appears that the phase behavior of the inner leaflet mixtures is dominated by the intrinsic cha

112 rol (Chol), which were selected to mimic the inner leaflet of a eukaryotic plasma membrane.

113 interactions of PIP(2) molecules within the inner leaflet of a lipid bilayer membrane with possible

114 verts during transport between the outer and inner leaflet of a membrane.

115 ylethanolamine and phosphatidylserine in the inner leaflet of asymmetric vesicles stabilized the form

116 outer membrane leaflet and subsequently the inner leaflet of Bacillus vesicles.

117 hospholipid that is normally confined to the inner leaflet of cell membrane bilayer, gets exteriorize

118 of lipids characteristically present in the inner leaflet of cell membranes (phosphatidylserine, pho

119 hatidylserine (PS) normally localizes to the inner leaflet of cell membranes but becomes exposed in a

120 ontaining phosphatidylserine, a lipid of the inner leaflet of cell membranes that is exposed in damag

121 o engineer hybrid structures comprised of an inner leaflet of diblock copolymer and an independent li

122 e utilized photoaffinity probes to label the inner leaflet of erythrocytes.

123 -PIP(2) into cells, and we measured D on the inner leaflet of fibroblasts and epithelial cells by usi

124 s (LPS) or lipooligosaccharides (LOS) and an inner leaflet of glycerophospholipids (GPL).

125 omponent of lipopolysaccharide (LPS), and an inner leaflet of glycerophospholipids (GPLs).

126 plying Mn (2+) ions on the outer but not the inner leaflet of lipid bilayers, the sidedness of protei

127 directly demonstrated FGF2 oligomers at the inner leaflet of living cells with a FGF2 dimer being th

128 6-(13)C]galactosylceramide prefers (70%) the inner leaflet of phosphatidylcholine vesicles.

129 er membrane is an asymmetric bilayer with an inner leaflet of phospholipids and an outer leaflet of l

130 ATP8B1 maintains PIP2 at the inner leaflet of plasma membrane (PM).

131 ociate more strongly with the outer than the inner leaflet of plasma membrane bilayers based on the r

132 acilitates association of the protein to the inner leaflet of plasma membrane, enhances migratory phe

133 P1A1 is a recruitment factor for FGF2 at the inner leaflet of plasma membranes that may control phosp

134 hosphatidic acid commonly present within the inner leaflet of plasma membranes, and potently disrupts

135 ate (PIP2) is a minority phospholipid of the inner leaflet of plasma membranes.

136 bilization, we found that cholesterol in the inner leaflet of PM plays an essential role in ligand-de

137 ATP8B1 maintains PIP2 at the inner leaflet of PM.

138 GalCer and localizing preferentially to the inner leaflet of POPC vesicles, dimyristoylphosphatidyle

139 while the same species incorporated into the inner leaflet of stomatocytic erythrocytes was highly di

140 w how the dimeric protein interacts with the inner leaflet of the bacterial outer membrane and that t

141 0.8 microg/mL of 1 is found, above which the inner leaflet of the bilayer is significantly perturbed.

142 atively charged phospholipids located in the inner leaflet of the bilayer membrane.

143 Substrate binding from the inner leaflet of the bilayer releases the protons and tr

144 ace of the cholesterol-ordered lipids in the inner leaflet of the bilayer; also, the TM helices in th

145 CADs are known to accumulate in the inner leaflet of the cell membrane where they bind to an

146 e membranes by interacting directly with the inner leaflet of the cell membrane.

147 ions where the PS content mimics that in the inner leaflet of the cell plasma membrane, the interacti

148 cteria, phospholipids are synthesized on the inner leaflet of the cytoplasmic membrane and must trans

149 sor for PG biogenesis, is synthesized in the inner leaflet of the cytoplasmic membrane and then trans

150 diacylglycerol from the outer leaflet to the inner leaflet of the cytoplasmic membrane where DAGK's a

151 DivIVA/GpsB proteins associate with the inner leaflet of the cytosolic membrane and act as scaff

152 Injected CagA localizes to the inner leaflet of the host cell membrane, where it hijack

153 assembly and budding of new virions from the inner leaflet of the host cell plasma membrane (PM).

154 in 1 (M1) is to form a polymeric coat on the inner leaflet of the host membrane that ultimately provi

155 nantly localized in reticulate bodies on the inner leaflet of the inclusion membrane.

156 to potentially sense lateral tension on the inner leaflet of the lipid bilayer caused by changes in

157 s have portals open to the cytoplasm and the inner leaflet of the lipid bilayer for drug entry.

158 rane phospholipid normally restricted to the inner leaflet of the lipid bilayer.

159 the first nucleotide binding domain near the inner leaflet of the lipid bilayer.

160 YidC.ribosome nascent chain complexes at the inner leaflet of the lipid bilayer.

161 a hydrophilic groove that is embedded in the inner leaflet of the lipid bilayer.

162 nsive lateral gate, which is open toward the inner leaflet of the membrane but closes upon drug bindi

163 he hydrophilic groove of YidC located in the inner leaflet of the membrane until it is translocated t

164 s how phospholipid can be recruited from the inner leaflet of the membrane without flipping its orien

165 )P(2) can flip from the outer leaflet to the inner leaflet of the membrane.

166 /acyl-acyl carrier protein synthetase on the inner leaflet of the membrane.

167 orming a 20-A-thick doughnut embedded in the inner leaflet of the OM with a central, amphipathic pore

168 he inner membrane (IM) or transferred to the inner leaflet of the outer membrane (OM).

169 The inner leaflet of the outer membrane contains phospholipi

170 luble enzyme with the former anchored to the inner leaflet of the outer membrane.

171 This requires Fe(3+) loading of Fbp at the inner leaflet of the outer membrane.

172 encoded Gag polyproteins are targeted to the inner leaflet of the plasma membrane (PM) for assembly,

173 HIV-1 assembly occurs at the inner leaflet of the plasma membrane (PM) in highly orde

174 G proteins largely function at the inner leaflet of the plasma membrane (PM) using covalent

175 c domains of the T cell receptor bind to the inner leaflet of the plasma membrane (PM), and a previou

176 troviral structural protein Gag binds to the inner leaflet of the plasma membrane (PM), and many cell

177 Within infected cells VP40 localizes at the inner leaflet of the plasma membrane (PM), binds lipids,

178 g of virally encoded Gag polyproteins to the inner leaflet of the plasma membrane (PM).

179 hospholipid, is predominantly located in the inner leaflet of the plasma membrane and has been propos

180 terminal domain (GSDMD(NT)) assembles on the inner leaflet of the plasma membrane and induces the for

181 VP40 interactions with lipid vesicles or the inner leaflet of the plasma membrane are electrostatic b

182 mally, phosphatidylserine is confined to the inner leaflet of the plasma membrane by an aminophosphol

183 ytosol, Ras proteins must be targeted to the inner leaflet of the plasma membrane for biological acti

184 own for targeting the Gag polyprotein to the inner leaflet of the plasma membrane for virus budding,

185 y of clathrin and many other proteins on the inner leaflet of the plasma membrane into clathrin-coate

186 Our data indicate that the inner leaflet of the plasma membrane is most negative, w

187 sion of proteins residing exclusively on the inner leaflet of the plasma membrane is regulated has be

188 Surface charges at the inner leaflet of the plasma membrane may contribute to r

189 Ebola virus assembles and buds from the inner leaflet of the plasma membrane of mammalian cells,

190 ns of Igalpha/Igbeta that is targeted to the inner leaflet of the plasma membrane of primary pro-B ce

191 phospholipid that resides exclusively on the inner leaflet of the plasma membrane of resting mammalia

192 nolamine (PE) are usually sequestered to the inner leaflet of the plasma membrane of the healthy euka

193 regulation of negative surface charge on the inner leaflet of the plasma membrane plays an integrativ

194 yn kinase and other proteins anchored to the inner leaflet of the plasma membrane redistribute select

195 Ras proteins on the inner leaflet of the plasma membrane signal from transie

196 roviral Gag polyproteins are targeted to the inner leaflet of the plasma membrane through their N-ter

197 etrovirus assembly, Gag proteins bind to the inner leaflet of the plasma membrane to initiate the bud

198 nus of podocin/MEC-2 has to be placed at the inner leaflet of the plasma membrane to mediate choleste

199 (MARCKS) sequesters phosphoinositides at the inner leaflet of the plasma membrane until MARCKS dissoc

200 K-Ras attaches to the inner leaflet of the plasma membrane via a farnesylated

201 ues and acidic phospholipids enriched in the inner leaflet of the plasma membrane were required for b

202 3) (or PIP(3)) is generated primarily in the inner leaflet of the plasma membrane where it is believe

203 basic JMD also binds to acidic lipids in the inner leaflet of the plasma membrane, and this interacti

204 from the site of protein translation to the inner leaflet of the plasma membrane, are poorly underst

205 umerous but the organization of PIP 2 in the inner leaflet of the plasma membrane, as well as the fac

206 yotic cells, an actin-based cortex lines the inner leaflet of the plasma membrane, endowing the cells

207 ospholipids are critical constituents of the inner leaflet of the plasma membrane, ensuring appropria

208 Several proteins expressed at the inner leaflet of the plasma membrane, including alpha-ac

209 Ras, a small GTPase found primarily on the inner leaflet of the plasma membrane, is an important si

210 erine (PS), a lipid normally confined to the inner leaflet of the plasma membrane, is exported to the

211 tidylserine (PS), normally restricted to the inner leaflet of the plasma membrane, is exposed on the

212 lserine, which is normally restricted to the inner leaflet of the plasma membrane, is exposed on the

213 aM; this suggests that they also bind to the inner leaflet of the plasma membrane, reducing its negat

214 containing lipids typically enriched in the inner leaflet of the plasma membrane, such as phosphatid

215 olipids that are normally sequestered to the inner leaflet of the plasma membrane, suggesting a role

216 elp to explain the behavior of PIP(2) on the inner leaflet of the plasma membrane, where it is involv

217 osphate (PIP(3)) are normally located in the inner leaflet of the plasma membrane, where these anioni

218 its major matrix protein to assemble at the inner leaflet of the plasma membrane.

219 re might be different pools of PIP(2) on the inner leaflet of the plasma membrane.

220 yrosine kinase Lyn, which is anchored to the inner leaflet of the plasma membrane.

221 tion occurs was found to be localized at the inner leaflet of the plasma membrane.

222 slocation of additional FA from the outer to inner leaflet of the plasma membrane.

223 re concentrated near the surface zone of the inner leaflet of the plasma membrane.

224 to simulate the presentation of cdE2 on the inner leaflet of the plasma membrane.

225 cells or anchored (via LynB protein) to the inner leaflet of the plasma membrane.

226 ids interact with the transporter within the inner leaflet of the plasma membrane.

227 e phospholipids, is normally confined to the inner leaflet of the plasma membrane.

228 tment of cytosolic signaling proteins to the inner leaflet of the plasma membrane.

229 , which forms a dense protein lattice on the inner leaflet of the plasma membrane.

230 noglycerophospholipids from the outer to the inner leaflet of the plasma membrane.

231 f an endogenous actin cortex attached to the inner leaflet of the plasma membrane.

232 ading to net transport from the outer to the inner leaflet of the plasma membrane.

233 ylinositol 3,4,5-trisphosphate (PIP3) in the inner leaflet of the plasma membrane.

234 e charges facing the lipid phosphates of the inner leaflet of the plasma membrane.

235 well established that VP40 assembles on the inner leaflet of the plasma membrane; however, the mecha

236 well established that VP40 assembles on the inner leaflet of the plasma membrane; however, the mecha

237 ds electrostatically to acidic lipids on the inner leaflet of the plasma membrane; interaction with C

238 ipid is restricted almost exclusively to the inner leaflet of the plasmalemma.

239 ost abundant negatively charged lipid on the inner leaflet of the PM and makes a major contribution t

240 In a typical mammalian cell, the inner leaflet of the PM is enriched in phosphatidylserin

241 uses an increased cholesterol content on the inner leaflet of the PM, associated with increased Rac1

242 thy cells, PS is actively sequestered to the inner leaflet of the PM, but PS redistributes to the out

243 sic Gag MA domain and the negatively charged inner leaflet of the PM.

244 l and envelope proteins while binding to the inner leaflet of the PM.

245 udies and simulated its interaction with the inner leaflet of the T cell plasma membrane.

246 53, the only lipoprotein associated with the inner leaflet of the Tp OM.

247 arcoplasmic reticulum (JSR) membrane and the inner leaflet of the transverse tubular ("T") sarcolemma

248 lindrical matrix protein layer linked to the inner leaflet of the viral envelope and with local order

249 wo interior layers of density apposed to the inner leaflet of the viral lipid bilayer were assigned a

250 he MA tyrosine kinase is associated with the inner leaflet of the viral membrane, while the tyrosine-

251 enhanced YFP that was incorporated into the inner leaflet of the viral membrane.

252 RV matrix protein VP40 (mVP40) underlies the inner leaflet of the virus and regulates budding from th

253 iffusion coefficient for other lipids on the inner leaflet of these cell membranes.

254 e show that PS is normally restricted to the inner leaflet of these cells.

255 at approximately two thirds of the PIP(2) on inner leaflet of these plasma membranes is bound reversi

256 The inner leaflet of this membrane likely is composed nearly

257 of fluorescent phospholipid in the outer and inner leaflets of Bacillus vesicles at the completion of

258 ms of domain induction between the outer and inner leaflets of cell plasma membranes do not necessari

259 nching of AOFA fluorescence in the outer and inner leaflets of the bilayer allows flip-flop to be sep

260 metrically distributed between the outer and inner leaflets of the plasma membrane in eukaryotic cell

261 ion by EM revealed immunoreactivity with the inner leaflets of the plasma membrane.

262 ded complex, including helix 8 burial in the inner leaflet, ordered lysine and arginine side chains i

263 This suggests the inner-leaflet-ordered domains were depleted in unsaturat

264 acterize how outer-leaflet Lo domains induce inner-leaflet-ordered domains, i.e., interleaflet coupli

265 BD-DOPE) was depleted in both the outer- and inner-leaflet-ordered domains.

266 en SM-rich outer-leaflet-ordered domains and inner-leaflet-ordered domains.

267 an asymmetric lipid bilayer that consists of inner leaflet phospholipids and outer leaflet lipopolysa

268 This architecture prevents access of inner leaflet phospholipids to the pore, but allows oute

269 is dynamically regulated by multiple anionic inner leaflet phospholipids.

270 te plasma membrane and results in sorting of inner leaflet phospholipids.

271 In contrast, when incorporated into inner leaflets, positive curvature agents led to full fu

272 n to have merged outer leaflets and distinct inner leaflets prior to formation of fusion pores.

273 tion sites on Lyn, was compared with another inner leaflet probe, EGFP-GG, which contains a prenylati

274 sibility that PE and PS could participate in inner-leaflet raft formation or stabilization.

275 eaflets of two bilayers are combined and the inner leaflets remain intact; however, hemifusion has be

276 egative countercharges within the membrane's inner leaflet remains intact in the closed conformation.

277 tively charged fluorescent lipids, while the inner leaflet remains unaffected.

278 s may have on the lipids and proteins of the inner leaflet remains unknown.

279 eptor laden exterior membrane leaflet to the inner leaflet, representing a potential mechanism for li

280 phospholipids (PLs) occupying the outer and inner leaflets, respectively.

281 Two long loops extend into the inner leaflet side of the cell membrane.

282 noglycerophospholipids from the outer to the inner leaflet, stimulated via phosphorylation by cortica

283 utside/PC inside vesicles, the PC-containing inner leaflet tended to destabilize ordered domain forma

284 symmetric plasma membrane has a destabilized inner leaflet that facilitates membrane fusion upon bind

285 with net positive curvature is formed by the inner leaflets that compose a hemifusion diaphragm.

286 when the Arg(694) side chain snorkels to the inner leaflet, the MSD peptide assumes a metastable conf

287 events the translocation of tetramers to the inner leaflet, thereby forestalling the formation of com

288 vely unfolded, it could anchor gravin to the inner leaflet through hydrophobic insertion of its N-ter

289 addition of Mg2+ increased the amount on the inner leaflet to approximately 30% by an unknown mechani

290 The two pairs of helices converge at the inner leaflet to create an intramembrane pocket with add

291 s a matrix layer beneath the plasma membrane inner leaflet to facilitate budding from the host cell.

292 pers, which scan the plasma membrane and its inner leaflet to flip lipophilic substrates to the outer

293 r stroke for movement of drug substrate from inner leaflet to outer leaflet of lipid bilayer.

294 erine (PS) is moved from the plasma membrane inner leaflet to the outer leaflet where it triggers rec

295 creased, whereas that in the DOPC-containing inner leaflet was largely unchanged, confirming asymmetr

296 Depletion of PS in the inner leaflet weakens actin cortex-plasma membrane attac

297 usion, lower concentrations of amphipaths in inner leaflets were required to promote transfer of aque

298 in specifically binds to the plasma membrane inner leaflet where it recognizes the target lipids phos

299 e majority of cholesterol was located on the inner leaflet, whereas on upregulation of transporters b

300 tricts the diffusion of TMPs and IMPs of the inner leaflet within the membrane skeleton corrals.