ライフサイエンスコーパス: inner membrane

1 tes with the outer side of the mitochondrial inner membrane.

2 ripherally associated with the mitochondrial inner membrane.

3 orms an oligomer that is associated with the inner membrane.

4 the secreted proteins through the bacterial inner membrane.

5 cassette (ABC)-transporter in the bacterial inner membrane.

6 ant receptors (GRs) localized in the spore's inner membrane.

7 LptC, extracts lipopolysaccharide out of the inner membrane.

8 nnel complex resident within the organelle's inner membrane.

9 bunit on the intermembrane space side of the inner membrane.

10 is in the cytoplasm and secretion across the inner membrane.

11 rochemical gradient (DeltamuH(+)) across the inner membrane.

12 the proper architecture of the mitochondrial inner membrane.

13 ch as dipicolinic acid (DPA) and the spore's inner membrane.

14 iated with an ABC transporter complex in the inner membrane.

15 E domain-containing proteins localise to the inner membrane.

16 mbrane proteins can be concentrated near the inner membrane.

17 rial matrix, where it is associated with the inner membrane.

18 dary membrane, thereby ensuring a contiguous inner membrane.

19 e permeability transition pore (PTP), in the inner membrane.

20 across the energy-transducing mitochondrial inner membrane.

21 ace, allowing formation of PE by Psd1 in the inner membrane.

22 med during insertion of the protein into the inner membrane.

23 lex) inserts multispanning proteins into the inner membrane.

24 rm protein, docking protein 4 (DOK4), on the inner membrane.

25 nit prohibitin-2 (PHB2) at the mitochondrial inner membrane.

26 drive protons across the energy-transducing inner membrane.

27 g motif along the periplasmic leaflet of the inner membrane.

28 in that mediates mitochondrial fusion at the inner membrane.

29 that is attached to a motor embedded in the inner membrane.

30 by pumping protons across the mitochondrial inner membrane.

31 into AC interactions with the mitochondrial inner membrane.

32 proton transporter across the mitochondrial inner membrane.

33 ossibly mistargeting stalled porins into the inner membrane.

34 bution bands is echoed by the folding of the inner membrane.

35 ers are a conserved feature of mitochondrial inner membranes.

36 ciates with the translocase of mitochondrial inner membrane 23 (TIM23) complex, resulting in inhibiti

37 ly if the function of the translocase of the inner membrane 23 is compromised such as in temperature-

38 cation of PyoG is dependent on the conserved inner-membrane AAA+ ATPase/protease, FtsH.

39 The Znu system consists of an inner membrane ABC transporter and an outer membrane Ton

40 re, the proton-motive force (PMF) across the inner-membrane acts at distinct stages of protein secret

41 xchange ADP for ATP across the mitochondrial inner membrane, an activity that is essential for oxidat

42 a T2SS nanomachines requires the assembly of inner membrane-anchored fibres called pseudopili.

43 YME1L is an inner membrane-anchored hexameric protease with distinct

44 Inner membrane-anchored long forms of OPA1 (l-OPA1) are

45 Inner membrane-anchored long OPA1 (L-OPA1) undergoes pro

46 with the lipid composition of mitochondrial inner membrane and analyze its oligomeric state by elect

47 ns, and nucleotides across the mitochondrial inner membrane and are crucial for many cellular process

48 swelling of the organelle, disruption of the inner membrane and ATP synthesis, and cell death.

49 sis, leading to accumulation of hTMCM in the inner membrane and delaying its conversion to trehalose

50 AA+ enzyme that controls proteostasis at the inner membrane and intermembrane space of mitochondria.

51 coordinating the action of LptB(2)FG in the inner membrane and Lpt protein interactions in the perip

52 ndrial reactive oxygen species occurs in the inner membrane and matrix compartments as a consequence

53 ondrial matrix, leading to disruption of the inner membrane and necrotic cell death.

54 ransporter LptB(2) FGC extracts LPS from the inner membrane and places it onto a periplasmic protein

55 ne to drive protons across the mitochondrial inner membrane and power oxidative phosphorylation.

56 ysaccharide from the external leaflet of the inner membrane and propels it along a filament that exte

57 UCP2 is located in the mitochondrial inner membrane and regulates production of reactive oxyg

58 el in which molecular reorganizations of the inner membrane and sequestration of outer membrane compo

59 ills E. coli by permeabilizing the bacterial inner membrane and subsequently binds the outer membrane

60 an apparatus for lipid export away from the inner membrane and suggest that the Mla pathway may have

61 anslocation of alpha-helical proteins across inner membrane and the assembly of outer membrane beta-b

62 LPS molecules are synthesized in the inner membrane and then transported to the cell surface

63 to permeabilize both the bacterial outer and inner membrane and thus kill a bacterium, MACs need to b

64 ds after their synthesis is completed at the inner membrane and transport them to the outer membrane.

65 produces OM constituents in the cytoplasm or inner membrane and transports these components across th

66 on density region, composed of the outer and inner membranes and the cristae cluster, which enclosed

67 binding is not sufficient for unclasping the inner-membrane and outer-membrane interactions of integr

68 hat connects the two membrane proteins CusA (inner membrane) and CusC (outer membrane).

69 exchanges ADP/ATP through the mitochondrial inner membrane, and Ant2 is the predominant isoform expr

70 swelling of the organelle, disruption of the inner membrane, and ATP synthesis, followed by cell deat

71 tribution of bioactives in pomegranate peel, inner membrane, and edible aril portion was investigated

72 abolites discriminated the pomegranate peel, inner membrane, and edible aril portion, as well as the

73 One arm lies in the inner membrane, and the other extends about 100 A into t

74 (Fe-S)(int) via the Atm1 transporter in the inner membrane, and we detected (Fe-S)(int) in active fo

75 nsducing proteins coupling the outer and the inner membranes, and inner membrane transporters.

76 This establishes a clear link between inner membrane architecture and functional decline.

77 m extended networks and exhibit an intricate inner membrane architecture.

78 t is cotranslationally translocated into the inner membrane are generally less highly translated than

79 pe, which comprises an outer membrane and an inner membrane, are an important and attractive system f

80 roteins, threaded through the channel in the inner membrane, are handed over to the import motor at t

81 l for lateral sorting of preprotein into the inner membrane, as well as maintaining mitochondrial mor

82 substrates that are laterally sorted to the inner membrane, as well as the mitochondrial matrix.

83 An inner membrane assembly platform and a cytoplasmic motor

84 The inner membrane assembly platform components PulC, PulE,

85 cleotide polymorphisms in mmpL3, encoding an inner membrane-associated mycolic acid flippase in M. tu

86 sfunction and cellular stresses activate the inner membrane-associated zinc metallopeptidase OMA1 tha

87 In mitochondria, CoQ lipids are built by an inner membrane-associated, multicomponent, biosynthetic

88 ers that are preferentially localized in the inner membrane at two opposing sides of the mitochondria

89 gnitude reduction in permeability across the inner membrane at weakly acidic pH and outer membrane at

90 transport into the cytoplasm via the cognate inner membrane ATP-binding cassette proteins.

91 SLC25A24 encodes a mitochondrial inner membrane ATP-Mg/Pi carrier.

92 a soluble periplasmic protein, MlaC, and the inner membrane ATPase, MlaFEDB complex.

93 s of cps-6 delays breakdown of mitochondrial inner membranes, autophagosome enclosure of paternal mit

94 embrane is composed of a double bilayer, the inner membrane being linked to the protein lamina networ

95 an either withdraw from or extend toward the inner membrane-bound PBP1A through peptidoglycan gaps an

96 signal peptides and are exported through the inner-membrane-bound Sec machinery to the periplasm, fol

97 tion requires the cleavage of both outer and inner membranes, but the mechanism of inner membrane cle

98 g cell stress, Bif-1 regulates mitochondrial inner membrane by interacting with prohibitin-2 to disru

99 inked O antigens are translocated across the inner membrane by the WzmWzt ABC transporter for ligatio

100 drial Ca(2+) uniporter complex (uniplex), an inner membrane Ca(2+) transporter and major pathway of m

101 tic ultrastructure with invaginations of the inner membrane called cristae that contain the protein c

102 the entropic and stretching energies of the inner membrane, cell wall, and outer membrane and that t

103 a 1.6-MDa hexameric nanomachine, forming an inner membrane channel for effectors to pass through.

104 ion of ComH with a periplasmic domain of the inner-membrane channel ComEC, which is known to mediate

105 er and inner membranes, but the mechanism of inner membrane cleavage is unclear.

106 Their highly convoluted contiguous inner membrane compartmentalizes the organelle, which is

107 The Toxoplasma gondii inner membrane complex (IMC) is an important organelle i

108 ructural scaffold of daughter parasites, the inner membrane complex (IMC), fails to form in this aggl

109 roteinaceous network, and referred to as the inner membrane complex (IMC).

110 rates of PfCDPK1, which includes proteins of Inner Membrane Complex and glideosome-actomyosin motor a

111 In the yeast Saccharomyces cerevisiae, this inner membrane complex is composed of 11 protein subunit

112 between the parasite plasma membrane and the inner membrane complex.

113 ntermediate filament cytoskeleton called the inner-membrane complex (IMC).

114 e two crystal structures of a five-component inner-membrane complex that contains all the proteins re

115 MotA and MotB form an inner-membrane complex that does not conduct protons and

116 structure is composed of distinct outer and inner membrane complexes and a connecting cylinder that

117 sted the connectivity of the cytoplasmic and inner membrane components of the type IVa pilus machiner

118 The inner-membrane components of the protein bridge comprise

119 ed a FUNDC1 interactome at the mitochondrial inner membrane, comprising the AAA+ protease, LonP1, and

120 The mitochondrial inner membrane consists of the inner boundary membrane a

121 outer membrane, before transport across the inner membrane, could have potentially useful biological

122 ne and active efflux via efflux pumps in the inner membrane creates a permeability barrier.

123 Furthermore, unfolding of inner membrane cristae is coupled to changes in the supr

124 ssemble into long ribbons at the rims of the inner membrane cristae.

125 synthase dimers indicate how they shape the inner membrane cristae.

126 rane curvature closely resemble those in the inner membrane cristae.

127 acterial cell-wall precursor lipid II on the inner membrane, disrupting the proton motive force.

128 tudy thus reveals that the morphology of the inner membrane does not influence the subcompartmental p

129 ensures correct nuclear placement toward the inner membrane domain.

130 at the substrate-binding protein DppA of the inner membrane Dpp transporter is required for heme and

131 In particular, OPA1, regulating inner membrane dynamics, cristae remodelling, oxidative

132 lyze recently solved structures of bacterial inner membrane efflux pumps as to how they bind and tran

133 lia of approximately 50 x 0.2 mum, devoid of inner membranes embedded in a mucus layer.

134 Biochemical studies revealed that MltG is an inner membrane enzyme with endolytic transglycosylase ac

135 the envelope-associated needle complex, the inner membrane export apparatus, and a large cytoplasmic

136 in precursor within the lipid bilayer of the inner membrane, followed by cleavage by the inner membra

137 ndrial cytochrome c oxidase assembles in the inner membrane from subunits of dual genetic origin.

138 During envelope stress, critical inner-membrane functions are preserved by the phage-shoc

139 rial membrane and functions in mitochondrial inner membrane fusion and cristae maintenance.

140 complex and proteolytic inactivation of the inner membrane fusion protein OPA1.

141 anges in the expression of the mitochondrial inner membrane fusion protein optic atrophy type 1, and

142 mtDNA) by deletion of mitochondrial outer or inner membrane fusion proteins (Fzo1p or Mgm1p) leads to

143 e describe a mechanism for how mitochondrial inner-membrane fusion is regulated by the ratio of two f

144 with type 1 diabetes exhibited mitochondrial inner-membrane hyperpolarization (MHP).

145 distinct mechanism related to mitochondrial inner-membrane hyperpolarization.

146 ate a hollow scaffold spanning the bacterial inner membrane (IM) (24-mer ring-forming proteins PrgH a

147 eukaryotes, one occurs in the mitochondrial inner membrane (IM) and is executed by phosphatidylserin

148 zes these toward distinct spatial locations, inner membrane (IM) and outer membrane (OM), thus formin

149 The inner membrane (IM) of mitochondria displays an intricat

150 negative bacteria are either retained in the inner membrane (IM) or transferred to the inner leaflet

151 ing to the proton motive force (PMF) via the inner membrane (IM) protein TonB1.

152 mbrane protein Large 3 (MmpL3), an essential inner membrane (IM) protein, is implicated in MA transpo

153 sts of an OMP, designated TamA, and a single inner membrane (IM) protein, TamB.

154 in which anterograde PL transport causes the inner membrane (IM) to shrink and eventually rupture; ch

155 substances and must be transported from the inner membrane (IM) to the outer membrane (OM) through a

156 rane (OM), a peptidoglycan (PG) layer and an inner membrane (IM)(1).

157 ter leaflet of the OM and return them to the inner membrane (IM).

158 tigates various problems that could increase inner-membrane (IM) permeability.

159 rphological alterations of the mitochondrial inner-membrane (IMM) have not been clearly elucidated.

160 chemical discontinuity among segments of the inner membrane, implying that individual cristae may ope

161 rial growth by causing depolarisation of the inner membrane in intoxicated cells, together with incre

162 small proton gradient was detected over the inner membrane in wild type or cristae-lacking cells.

163 he present study, we show that mitochondrial inner membranes in leg muscles of endurance-trained athl

164 rotein import gate, the TOM complex, and the inner membrane insertion of metabolite carriers.

165 to the four subcompartments: outer membrane, inner membrane, intermembrane space, or matrix.

166 he polymerization of the protein MreB at the inner membrane into a sturdy cytoskeleton capable of tra

167 ynthesized in the cytoplasmic leaflet of the inner membrane is flipped to the periplasmic leaflet by

168 for MltG, which revealed that access to the inner membrane is important for its in vivo activity.

169 ing force for their translocation across the inner membrane is provided by the presequence translocas

170 stems, the respirasome, in the mitochondrial inner membrane is reported in this issue of Cell.

171 aments, the monomeric pilin reservoir in the inner membrane is sensed by the 17-amino acid transmembr

172 for proper architecture of the mitochondrial inner membrane, is localized primarily at crista junctio

173 dient via ATP synthase located on the folded inner membrane, known as cristae.

174 dient via ATP synthase located on the folded inner membrane, known as cristae.

175 protein, Lpp, at the periplasmic face of the inner membrane leads to lethal inner membrane-peptidogly

176 on, and DHA-lysoPC is transported across the inner membrane leaflet of the BBB via the major facilita

177 main is positioned in close proximity to the inner membrane leaflet, enabling the reduction of membra

178 on, PIP2 occupies a site on KCNQ1 within the inner membrane leaflet, which triggers a large conformat

179 ative zinc catalytic site are exposed to the inner membrane leaflet.

180 in-cholesterol interactions in the outer and inner membrane leaflets.

181 of the Fmr1(-/y) mouse have a mitochondrial inner membrane leak contributing to a "leak metabolism."

182 ose synthase subunit G (BcsG) is a predicted inner membrane-localized metalloenzyme that has been pro

183 nt studies suggest how gliding motors in the inner membrane may transduce force to the cell surface.

184 ransporters, and the structure of the entire inner-membrane MlaFEDB complex remains unknown.

185 o form of MlaC, we provide evidence that the inner-membrane MlaFEDB machinery exports phospholipids t

186 ave lower intramitochondrial levels, whereas inner membrane multispan proteins that are imported via

187 ty to selectively disrupt the OM but not the inner membrane of E. coli.

188 insertion into and translocation across the inner membrane of E. coli.

189 ed overexpression of functional PfVIT in the inner membrane of Escherichia coli which, in turn, confe

190 SecA secretion motor for insertion into the inner membrane of Escherichia coli.

191 e synthesized at the periplasmic side of the inner membrane of Gram-negative bacteria and are then ex

192 or magainin 2 to membranes representing the inner membrane of Gram-negative bacteria, comprising a m

193 ated GTPase M (IRGM) in human locates at the inner membrane of mitochondria and is best known for its

194 sicles, and lipid monolayers) that mimic the inner membrane of P. aeruginosa The study demonstrated t

195 egrity of the cell envelope by depleting the inner membrane of phospholipids.

196 rchitecture that extends above and below the inner membrane of the bacterium.

197 ith COX2 to promote translocation across the inner membrane of the COX2 C-tail that contains the apo-

198 ubtilis, germinant receptors assemble in the inner membrane of the developing spore.

199 e permeability transition pore (PTP), in the inner membranes of mitochondria can be triggered by calc

200 consequence, a loss of impermeability of the inner membranes of spores, accompanied by a decrease in

201 OPH is targeted to the inner membrane ofBrevundimonas diminutain a pre-folded c

202 s are assembled on the cytosolic side of the inner membrane on a lipid anchor and reoriented to the p

203 bout 50% of mitochondria from old flies, the inner membrane organization breaks down.

204 the outer membrane and returning them to the inner membrane), others have asserted the opposite.

205 rmed time-lapse imaging of the mitochondrial inner membrane over 50 min (3.9 s per frame, with 71.5 s

206 Alternative oxidase (AOX) is a mitochondrial inner-membrane oxidase that accepts electrons directly f

207 inner membrane, followed by cleavage by the inner membrane peptidase.

208 c face of the inner membrane leads to lethal inner membrane-peptidoglycan linkages.

209 ing, confocal live imaging for mitochondrial inner membrane polarity, and immunohistochemistry.

210 and the absence of exogenous substrates upon inner membrane pore formation by alamethicin or Ca(2+)-i

211 olated rabbit cardiac mitochondria following inner membrane pore formation induced by either alamethi

212 bacterial cytoplasm to the periplasm via an inner-membrane pore complex (TraC and TraG) with homolog

213 Surprisingly, a high mitochondrial inner membrane potential was maintained in MitoPark SNc

214 s is counterbalanced by a high mitochondrial inner membrane potential, even under conditions of sever

215 iated Ca(2+) uptake is driven by the sizable inner-membrane potential generated by the electron-trans

216 mitochondrial calcium uniporter expression, inner membrane potentials, or the mitochondrial permeabi

217 ase and thereby maintains quality control of inner membrane preproteins sorting.

218 A mitochondrial inner-membrane protease, PARL, removes an autoinhibitory

219 r the regulated processing of YME1L by other inner membrane proteases such as OMA1.

220 ed cooperative and sequential actions of two inner membrane proteases, Oma1p and Yme1p.

221 orescently labeled TcpP, but not for another inner membrane protein (TatA).

222 nsporters import nutrients by coupling to an inner membrane protein complex called the Ton complex.

223 of outer membrane, periplasmic adaptor, and inner membrane protein components.

224 in the cell envelope: OmpA competes with the inner membrane protein IgaA, the downstream Rcs componen

225 Here we characterize the inner membrane protein PbgA and report that its depletio

226 Typhimurium (S Typhimurium) relies upon the inner membrane protein PbgA to enhance outer membrane (O

227 ink between mitochondrial protein import and inner membrane protein quality control.

228 e mechanism is analogous to that used by the inner membrane protein TonB to dislodge the plug domains

229 How the inner membrane protein YejM with its periplasmic domain

230 ationally recognizes the nascent chain of an inner membrane protein, RodZ, with high affinity and spe

231 Smt1p is an intrinsic inner membrane protein, which, based on its sedimentatio

232 However, the detailed mechanism of how the inner-membrane protein TonB connects to the transporters

233 the periplasm in a process dependent on the inner-membrane protein TonB.

234 equencing revealed that degradation rates of inner-membrane-protein mRNAs are on average greater that

235 s and that this selective destabilization of inner-membrane-protein mRNAs is abolished by dissociatin

236 matrix proteins and a considerable number of inner membrane proteins carry a positively charged, N-te

237 gs identify a new route for the targeting of inner membrane proteins in bacteria and highlight the di

238 lized for the synthesis of several essential inner membrane proteins of the respiratory chain.

239 ted in the bacterial cell, mRNAs that encode inner-membrane proteins can be concentrated near the inn

240 ism of targeting, insertion, and assembly of inner-membrane proteins exist.

241 e of the SecYEG translocon consists of three inner-membrane proteins, SecY, SecE, and SecG, which, to

242 enormous variety of different secretory and inner-membrane proteins.

243 ty of MmpL3 rather than by inhibition of the inner membrane proton motive force, significantly advanc

244 ry focus on the assembly and function of the inner membrane pumps.

245 inor coat protein named pIII and a bacterial inner-membrane receptor, TolA, which is part of the cons

246 ct interactions between PilA and PilS in the inner membrane reduce pilA transcription when PilA level

247 family, mediates fusion of the mitochondrial inner membranes, regulates cristae morphology, and maint

248 n of preproteins across the Escherichia coli inner membrane requires anionic lipids by virtue of thei

249 mplex II (site IIf); (b) pore opening in the inner membrane resulting in rapid efflux of succinate/fu

250 g., 16 Leu) are stably incorporated into the inner membrane, resulting in a C-terminal anchored membr

251 ds interface with the 24-fold symmetric SctD inner membrane ring (IR) via an adaptor protein (SctK).

252 m interactome and interactions with the T3SA inner membrane ring (IR).

253 -particle cryo-electron microscopy, with the inner-membrane-ring and outer-membrane-ring oligomers de

254 is dependent on its interaction with nuclear inner membrane Sad1/UNC-84 (SUN) domain proteins SUN1 an

255 r environmental signals to the cytoplasm via inner-membrane sigma regulators.

256 ers transport protons from the mitochondrial inner membrane space into the mitochondrial matrix indep

257 levels of cardiolipin (CL), a mitochondrial inner membrane-specific lipid.

258 a ROMO1 knockout cell line revealed aberrant inner membrane structure and altered processing of the G

259 ediates of the assembly process including an inner-membrane sub-complex consisting of the C-ring, MS-

260 mation of cristae creates more mitochondrial inner membrane surface area and thus more protonic capac

261 However, increasing the mitochondrial inner membrane surface comprises an alternative mechanis

262 in biochemical coupling at the mitochondrial inner membrane that enhance O2 efficiency.

263 ds to fragmented mitochondria with disrupted inner membranes that are unable to maintain a proton gra

264 self-assembling GTPase that forms, below the inner membrane, the mid-cell Z-ring guiding bacterial di

265 is a complex structure that consists of the inner membrane, the periplasm, peptidoglycan and the out

266 x is usually present but disengaged from the inner membrane, the T2SS has a much longer periplasmic v

267 sence of a reduced form of the translocon of inner membrane, they failed to identify any outer-membra

268 teins (OMPs) - are first secreted across the inner-membrane through the Sec-translocon for delivery t

269 translocons on the outer membrane (TOM) and inner membrane (TIM).

270 the mitochondrial matrix are targeted to the inner membrane Tim17/23 translocon by their presequences

271 er the electrochemical gradient across their inner membrane to allow ATP synthesis while maintaining

272 The permeability of the mitochondrial inner membrane to HNO2, but not to NO2(-), combined with

273 nt protein complex and ATP hydrolysis at the inner membrane to promote GPL export to the OM.

274 tes transport of lipopolysaccharide from the inner membrane to the cell surface(1).

275 ulence factors from the outer leaflet of the inner membrane to the periplasm.

276 xbD, and uses the proton motive force at the inner membrane to transduce energy to the outer membrane

277 ded translocation of IRAK2 into mitochondria inner membranes, to suppress oxidative phosphorylation a

278 Moreover, the inner membrane transglycosylase protein P26 could have a

279 Inner-membrane translocation of PyoG is dependent on the

280 A into the periplasm and its delivery to the inner membrane translocator ComEC.

281 Our findings explain how the inner-membrane transport complex controls efficient unid

282 omain protein MlaD is known to be part of an inner membrane transporter that is important for mainten

283 analysis suggested that PEG344 serves as an inner membrane transporter.

284 pling the outer and the inner membranes, and inner membrane transporters.

285 two sites by passing along the mitochondrial inner membrane using the hydrophobic nature of the acyl

286 Both complexes build in the mitochondrial inner membrane various supramolecular assemblies.

287 reconstituting them in vitro using inverted inner membrane vesicles.

288 proton-motive force-linked Tol system in the inner membrane via porins after first binding an outer m

289 insertion into and translocation across the inner membrane, were unaffected.

290 eading to its activation and transfer to the inner membrane, where it dephosphorylates P-Y419Src (act

291 nslocator (ANT) located in the mitochondrial inner membrane, which leads to a high cytosolic ATP/ADP

292 tein insertion from the matrix side into the inner membrane while Cytochrome c oxidase assembly prote

293 the proton motive force generated across the inner membrane with energy-dependent pyocin translocatio

294 protein is integrated into the mitochondrial inner membrane with it's C-terminus exposed to the inter

295 ed for the flagellar motor starting from the inner membrane, with the addition of each new component

296 ocation of trehalose monomycolate across the inner membrane without altering the proton motive force.

297 coccoids to be identified, targets H. pylori inner membrane without disrupting it, as visualized by c

298 nslocate substrates across the mitochondrial inner membrane without previous unfolding.

299 outer membrane rather than between wall and inner-membrane, yet still obtain nutrients from the prey

300 the absence of ROMO1, mitochondria lose the inner membrane YME1L protease, which participates in OPA