ライフサイエンスコーパス: inocula

1 rial genomes/mouse, respectively) ehrlichial inocula.

2 L vials using environmental water samples as inocula.

3 Growth detection was better with larger inocula.

4 ning, suppresses virulence even at very high inocula.

5 were highest in mice given the larger virus inocula.

6 to determine IL-10 production with variable inocula.

7 to growth detection was shorter with larger inocula.

8 s of pharyngeal flora (PF) were added to the inocula.

9 sed, along with incremental amounts of PRRSV inocula.

10 ocyte responses with both nonfatal and fatal inocula.

11 s, and the necessity for using high starting inocula.

12 inoculation and by different types of viral inocula.

13 m DbpA hyperimmune mice, compared with input inocula.

14 d mice revealed no ospC variation from input inocula.

15 may confer protective immunity by lysing the inocula.

16 ver a wide range of infectivity of the virus inocula.

17 n microbial colonies present in the spoilage inocula.

18 sing fecal samples from three infants as the inocula.

19 pattern of sulfate reduction with different inocula.

20 ding fermentation pathways compared to other inocula.

21 to positive detection of the growth of small inocula.

22 at low inocula but lethal at 2.5-fold higher inocula.

23 gradable in aerobic microcosms with all soil inocula.

24 rtional to the parasite concentration in the inocula.

25 lti-strain consortia than with single-strain inocula.

26 n 10(4) and 10(5) inocula or 10(4) and 10(6) inocula.

27 fected with either the clonal or the diverse inocula.

28 , and spleen of mice that received sublethal inocula.

29 strains, prepared from both liquid and solid inocula.

30 between mice injected with the different RML inocula.

31 or sCJD(VV2) prion strains and were used for inocula.

32 st VS-mediated inocula compared to cell-free inocula.

33 n be lost rapidly after exposure to low-dose inocula.

34 as corrected by adding inorganic iron to the inocula.

35 from both exponential- and stationary-phase inocula.

36 6 g/liter casein using 0.5 and 2.0 McFarland inocula.

37 represented the full genetic spectra of the inocula.

38 on of PCho+ variants compared to that in the inocula.

39 Following sublethal inocula (1 x 10(7) CFU), the intra-abscess burdens of vi

40 14, 18c, 19f, and 23f were used as challenge inocula (1-1500 cfu) in a model of pulmonary infection t

41 me equivalents [GE] per animal) and low-dose inocula (10 degrees GE per animal) primed the CD4 T-cell

42 iation between the two processes at low dose inocula (10(-6)-10(-8) diluted brain material).

43 tly different viral kinetics, both high-dose inocula (10(10) genome equivalents [GE] per animal) and

44 Smaller inocula (10(2)) survived for shorter times but still gen

45 lence in the IE model across three challenge inocula (10(4) to 10(6) CFU) in terms of achievable intr

46 Two different inocula (10(8) and 10(7) CFU) were compared for optimiza

47 Here, we combine distinct community inocula (a biotic factor) with different temperature and

48 eks and 72 to 76 weeks) were infected with 2 inocula: a survivable dose of 50 PFU and a lethal dose o

49 At inocula above 10(5) pfu the course and severity of corne

50 Whether the yield benefits of such inocula allow modified nutrient and water management con

51 erved dechlorination of 1,2,3,4-TeCDD by all inocula, although to different extents.

52 Standardized inocula and 5 ml of blood were added to each bottle.

53 strains that were lethal at low intravenous inocula and achieved very high early, and persistent, bl

54 We evaluated the soil microbiome in the inocula and after chrysanthemum growth, as well as plant

55 ted these six species individually with soil inocula and exposed them to two watering treatments (wel

56 This effect was most pronounced at lower inocula and imaging correlated well with qPCR data.

57 cultured monocytes by using identical viral inocula and indicator systems.

58 We show that inocula and inoculated soil in which a focal plant had g

59 n Ab doses after i.p. infection with defined inocula and promoted phagocytosis, agglutination, and th

60 thematical analysis of infections with mixed inocula and segregative plasmid experiments.

61 ficant correlation between the viral load of inocula and the ability of HIV-1 to pervade the squamous

62 nt) strains were nonlethal at 20-fold higher inocula and were efficiently cleared by early time point

63 erimental anaerobically stressed Aspergillus inocula, and 10,062 consecutive clinical specimens.

64 d not produce cytolytic injury, even at high inocula, and exhibited decreased cellular invasion.

65 IgG1, IgG2a, IgG2b, and IgG3 dose, infective inocula, and protection was investigated in a mouse mode

66 imilar to that seen with those given control inocula, and there was no difference in disease developm

67 This effect is prevented when inocula are grown in an excess of glucose, but not in an

68 CVD 1207 was remarkably well-tolerated at inocula as high as 10(8) CFU.

69 e of S. aureus, and they were colonized with inocula as low as 10(5) CFU.

70 strains tested and killed caterpillars with inocula as low as 20 CFU/caterpillar.

71 limited susceptibility to certain of the CWD inocula, as evidenced by incomplete attack rates and lon

72 inoculum followed over time and with varying inocula assayed at a single time point.

73 vercame this problem by collecting microbial inocula at subfreezing conditions under eCO(2) and warmi

74 Virulent strains were nonlethal at low inocula but lethal at 2.5-fold higher inocula.

75 tality had no effect on the abundance of EMF inocula, but led to altered EMF community composition in

76 with a suction pen previously used with high inocula, but rinsed in ethanol and stored dry (6 months)

77 In the kidney, conversely, wild-type inocula causing no or low mortality induced type 1 respo

78 e strains at various intratracheal challenge inocula (CI).

79 te equivalent endotoxin contents between the inocula, CO99-infected animals had a median survival of

80 72-fold reduced efficacy against VS-mediated inocula compared to cell-free inocula.

81 The susceptibility to classical scrapie inocula could be assessed in Drosophila transgenic for p

82 In the current study, more modest low dose inocula delivered by the aerosol route grew identically

83 Previous studies using high inocula demonstrated that environmental V. fischeri cell

84 to otherwise nonfatal gram-negative bacteria inocula, demonstrating the pivotal role played by these

85 Inocula derived from late-stationary-phase cultures, des

86 r findings were consistent between microbial inocula derived from two municipal wastewater treatment

87 or CD8(+) T(BM), recipients of donor HSC+FC inocula did not exhibit significant clinical or histolog

88 iffusion testing (dDD) using nonstandardized inocula directly from blood cultures could facilitate ea

89 method can be performed accurately by taking inocula directly from CHROMagar.

90 removed lethal doses (99.98%) of prions from inocula, effectively preventing disease in the mice.

91 eron in the presence of glucose explains the inocula effects.

92 Animals treated with high inocula failed to clear bacteria from the lungs, had sev

93 nsidered in the rational design of microbial inocula, followed by a scrutiny of the method of microbi

94 atory clavulanate effects were seen for both inocula for all ESBL-producing strains with all antimicr

95 to simplify the accurate standardisation of inocula for experiments.

96 robes and improving stress-adapted microbial inocula for human use.

97 ted or ungerminated conidia could be used as inocula for in vitro susceptibility studies of A. fumiga

98 Conidia are used as inocula for the in vitro susceptibility testing of Asper

99 We confirmed that the inocula for these experiments were grown under condition

100 For the PCR scheme, inocula for van gene detection were taken directly from

101 months, L-GLDA was ready biodegradable using inocula from 12 WWTPs.

102 Additional studies using inocula from 96GG deer showed no transmission to 96SS Pr

103 We used inocula from a Northern river (2.7 C) and a Central Euro

104 , 2,5-, and 2,3-DCNB) was investigated using inocula from an industrial site in the northeast of Braz

105 In the glasshouse, soil inocula from beyond-range tended to increase plant growt

106 enerally preserved inoculum composition, and inocula from different subjects yielded source-specific

107 The community shift of the inocula from four donors in response to 1 % (w/v) disacc

108 Here we analyse the inocula from Leishmania mexicana-infected Lutzomyia long

109 Cells were infected with inocula from multiple prion strains and in different bio

110 Producing rhinovirus (RV) inocula from nasal secretions has required prolonged obs

111 PBC separator produces McFarland equivalent inocula from positive blood cultures within 1 h, facilit

112 a particular assay to initially standardize inocula from virus stocks.

113 Etest using 0.5 and 2.0 McF inocula gave sensitivities and specificities of 82 and 9

114 , the non-native biomass increased with soil inocula generated by different non-native diversity.

115 he non-native biomass did not depend on soil inocula generated by non-native diversity.

116 Enterobacterales were comparable to 0.5 McF inocula generated from bacterial colonies in both CFU/ml

117 EC pairs were comparable with both media and inocula (geometric mean ranges of MECs and MICs, respect

118 nd glasshouse, one of the two range interior inocula had a positive effect on plant fitness.

119 Representative inocula had high titers of infectious virus (approximate

120 Animals treated with low inocula had systemic changes consistent with systemic in

121 ures and original, unamended sediment as the inocula in a secondary experiment with 2,3,7,8-tetrachlo

122 s and the highest similarity to the clinical inocula in both health and disease.

123 t artificial dosing with different microbial inocula in early life alters not only the RE transcripto

124 terial mutants, strains and species in mixed inocula in the host, rhizosphere and soil environments.

125 that of wild-type C. muridarum Nigg in mixed inocula in vitro and in vivo.

126 responses of mice of both ages and with both inocula included in the data (95% accurate for younger m

127 C57BL/6 mice injected with P. berghei inocula incubated with supraphysiological doses of NO (<

128 lity induced type 1 responses and 100% fatal inocula induced type 2 or interleukin-10 (IL-10)-dominan

129 At all virus inocula, inhibition by antibody was enhanced when target

130 ctions and improve the ability of biological inocula involving AM fungi and bacteria to enhance the s

131 virions and provirions) typically present in inocula is responsible for the normally asynchronous nat

132 To achieve bacteremia with low inocula, it was necessary to passage the isolates in rat

133 Two other inocula known to catalyze anaerobic hydrocarbon metaboli

134 oducible isolation of H. pylori, even at low inocula (< or =10(2) CFU/ml of saliva), despite the pres

135 ents and suggest that the cervid-derived CWD inocula may have contained or diverged into at least two

136 Viral inocula obtained from cells recovered after cytopathic i

137 ins and to the avirulent rad52/rad52 null at inocula of 1 x 10(6) and 1.5 x 10(6) cells.

138 saline: even under refrigerated conditions, inocula of 10(2) and 10(3) CFU/ml exhibited growth at 21

139 Inocula of 10(3) to 10(6) bacteria/5 micro L were used,

140 -lactamases gave consistent MIC results with inocula of 10(5) and 10(6) CFU/ml.

141 screened for vancomycin resistance by using inocula of 10(5) or 10(6) CFU dispensed by pipet and by

142 failed to form colonies on agar media while inocula of 10(5)-10(6) cells per plate formed a lawn.

143 Detection rates improved with inocula of 100 and 1,000 CFU S. agalactiae, with the maj

144 With low inocula of 130 isolates of CPE, the sensitivities of the

145 Groups of mice received tumor cell inocula of 2 x 10(5), 4 x 10(5), or 8 x 10(5) B16F10 cel

146 t subcutaneous and intraperitoneal challenge inocula of 3 x 10(2) and 3.2 x 10(1) CFU, respectively,

147 In the murine abscess model using equal inocula of a DeltasfaA or DeltasbnD mutant and the wild-

148 ody (mAb), by immunizing mice with sublethal inocula of a hypervirulent XDR clinical isolate.

149 In competition experiments using equal inocula of a norB or tet38 mutant and parent strain MW2,

150 Conidial inocula of an optical density at 530 nm (OD(530)) of 0.1

151 ontemporaneous exposure to a large amount of inocula of Aspergillus within 30 days of receiving high

152 e first step, regardless whether the initial inocula of B. burgdorferi expressed either all (cultured

153 Infection with high inocula of BCG-TNF resulted in bacterial clearance, but

154 the results from the mice infected with high inocula of BCG-vector.

155 Sublethal inocula of BG2 (1 x 10(8) or 1 x 10(7) CFU) caused perit

156 Mice infected with massive inocula of C. difficile spores were treated with differe

157 Survival of rats with large intrastriatal inocula of C6trkA cells was significantly longer than fo

158 le additions of 5 nM CFTR peptide 103-117 to inocula of either cytotoxic (exoU+) or noncytotoxic P. a

159 RNA sequences in animals given the identical inocula of HIV-2287.

160 hanisms by which antibodies neutralize large inocula of human immunodeficiency virus type 1 (HIV-1) o

161 ination disclosed that gC was present in the inocula of infected cells, but no new gC biosynthesis oc

162 Furthermore, DRrejTs rejected follow-up inocula of lymphoma cells, demonstrating that DRrejTs pe

163 d Nlrc4(-/-) mice using sublethal intranasal inocula of P. aeruginosa strain CHA expressing or not a

164 tor-deficient mice challenged with sublethal inocula of Pseudomonas become superinfected with seconda

165 s model of intrapulmonary infection uses low inocula of S. pneumoniae and results in bacteremia, meni

166 IM, we propose that human-derived high-titer inocula of several viral genotypes with extensive virolo

167 replication in macaques receiving identical inocula of SIV.

168 nal infection of infant rats with increasing inocula of Streptococcus pneumoniae resulted in a dose-d

169 Inocula of the 10 S. pneumoniae serotypes producing bact

170 In contrast, equal inocula of the hemolytic E. coli strain produced signifi

171 ective against a secondary challenge by high inocula of the homologous type I or a distinct type II T

172 ive mice, in challenge infections with mixed inocula of the immunizing (homologous) strain and a hete

173 ered supernatants of 24-h cultures for small inocula of the same strain to multiply to ca. 10(9) CFU/

174 mpare and optimize the efficacy of microbial inocula of varying diversities, structures, and provenan

175 hieve therapeutic benefit in patients, large inocula of virus will likely be necessary to establish t

176 red by comparing the performance of the same inocula on different host populations, individuals and t

177 ather than as growth responses of more dense inocula on MTZ-containing medium.

178 ures to evaluate the effect of various viral inocula on the development of vaccinia keratitis in rabb

179 With higher bacteria inocula, only W/Wv mice died (80%).

180 sizes were observed between 10(4) and 10(5) inocula or 10(4) and 10(6) inocula.

181 remia were identical to viruses found in the inocula or differed from them by only one or a few nucle

182 <26 days) compared to bioreactors with other inocula or substrates.

183 , acetate, formate and H2 from two different inocula over 3 years.

184 y, when competed against its parent in mixed inocula, PMF8 became the predominant symbiont present in

185 of-of-concept study demonstrates that eQUANT inocula prepared from clinically significant species of

186 BD ozone generator for treatment of spoilage inocula prepared from combinations of spoiled green bean

187 The results for inocula prepared from CWD-positive deer with or without

188 contrast, intermediate (10(7) and 10(4) GE) inocula primed the T-cell response before detectable log

189 pernatants from apoptotic cells to bacterial inocula prior to infection of naive cells increased the

190 Penile exposure to more concentrated virus inocula produced similar rates of infection in all anima

191 ivity against primary R5 strains of HIV-1 at inocula ranging from 100 to 20,000 50% tissue culture in

192 e inoculated Abeta polymers, and thus, these inocula represent distinct synthetic Abeta prion strains

193 Inocula representing physiologically relevant infecting

194 covered CFU and histopathology; however, the inocula required for identical frequency and magnitude o

195 itutive expression of bcl-2 in the expanding inocula restored recall responses to HY at a substantial

196 ge of multiplicity of infection, but smaller inocula resulted in delayed detection of apoptosis.

197 -11-month-old mACE2(H353K) mice, a 10(4) PFU inocula resulted in diffuse alveolar disease manifested

198 adily identified as escape flares from mixed inocula seeded on agar.

199 These inocula should first be tested in human volunteers in a

200 Microcosms constructed using field inocula show that sediment microbial communities are res

201 posed to classical or atypical scrapie prion inocula showed a faster decrease in locomotor activity t

202 Initially all sludge inocula showed limited biodegradation ability, but as ma

203 mmaRIIb-deficient mice challenged with large inocula showed reduced survival.

204 n vitro susceptibility testing with standard inocula showed that all five AmpC-producing strains were

205 of blastomycosis with either yeast or spore inocula showed that the bys1-silenced strains were as vi

206 so observed in microcosms that received both inocula simultaneously.

207 The effect of Mycobacterium tuberculosis inocula size on T cell priming in the lymph node and eff

208 munodeficiency virus type 1 (HIV-1)-infected inocula, such as genital secretions, breast milk, and bl

209 In parallel infections using inocula supplemented with an inducing 2 microM concentra

210 om the kidneys of monoinfected mice at the 4 inocula tested (P=.015 to P=.049), and 50% infective dos

211 All seven soil inocula tested were able to readily reduce NTO to 3-amin

212 stance is obtained more rapidly and at lower inocula than wild-type parasites.

213 ected from oral infections with C. rodentium inocula that infected the majority of Cnlp-/- mice.

214 predominate in settings with lower bacterial inocula that more closely mimic what initially occurs in

215 Despite use of identical inocula, the CFU per eye were greater for the parent tha

216 n a requirement for relatively high conidial inocula to achieve 100% mortality in both BALB/c and C57

217 , Culturette EZ allowed < 1% of the original inocula to be recovered after 24 h.

218 ted mice, strains required 10(5)-fold-higher inocula to cause an identical disease process as with ir

219 rom cannulated cattle and sheep were used as inocula to examine in vitro the effect of 20:5n-3 (EPA),

220 ed cultures of this strain and allowed small inocula to initiate growth in liquid culture.

221 logy, we administered S alvi and/or L passim inocula to newly emerged worker bees from four genetic b

222 out diarrhea may reflect recent ingestion of inocula too small to cause disease in otherwise suscepti

223 Compared with the broth-grown inocula, transcription of the H. ducreyi ulaABCD operon,

224 One of eight cervid brain inocula transmitted disease to Tg(MoPrP)4053 mice overex

225 lution, Etest at 0.5 and 2.0 McFarland (McF) inocula, two agar screening methods, and population stud

226 e in a mouse peritonitis model, and, at high inocula, TX10100 was either not lethal or was much less

227 established with a wide range of C. albicans inocula under supraphysiologic and near-physiologic (at

228 In mock-infected mice, by contrast, >95% of inocula up to 50-fold higher was efficiently cleared.

229 The inocula used in the rechallenge studies induced typical

230 lig4/lig4/rad52/rad52, was avirulent at all inocula used.

231 depending on both the Ab dose and infective inocula used.

232 The hemoglobin level in the inocula was about 8 muM; the hemoglobin was mainly oxyhe

233 nontransgenic population are used as T cell inocula, we noted decreased CD4 expansion when Class II

234 When opsonized inocula were adjusted so that they adhered to macrophage

235 rm, low-titer colonization whereas high-dose inocula were associated with acute bacterial replication

236 Low-dose inocula were associated with short-term, low-titer colon

237 gly, several woodchuck hepatitis virus (WHV) inocula were characterized.

238 Inocula were limited to specimens that appeared unimicro

239 ure cysts of Acanthamoeba not evident in the inocula were observed in sparse numbers in all dried sol

240 Standardized inocula were placed on the debrided corneal surface of o

241 In that report, low inocula were sufficient to cause infection in 18 and ill

242 ethods were significantly reduced when lower inocula were used with a prolonged incubation time.

243 When sublethal inocula were used, however, the Deltaplb1-2 mutant was a

244 arthritis; even in cases of larger challenge inocula, which allow their persistence in joints at a le

245 experiments performed with different faecal inocula, while nine other Firmicutes OTUs showed > 5-fol

246 Standardized inocula will enable the study of mechanisms that initiat

247 These results indicate that inocula with different concentrations of parasites gener

248 Only treatment of inocula with NO doses nearing saturation (> or =1.2 mM)

249 he microbial composition of the experimental inocula with that of the communities we detected associa

250 s expressing beta-lactamases were studied at inocula within 0.5 log unit of the standard inoculum, us

251 st whether infection with higher aerosolized inocula would lead to increased priming of M. tuberculos

252 ish a lethal infection from relatively small inocula, yet the effect of infectious dose upon CD4 T ce