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1 tive, a channel that is otherwise anesthetic insensitive.
2 e calcium-sensing RCK domain are practically insensitive.
3 )-OT response in mOTR and hOTR cells was PTX insensitive.
4 e level of initial release, i.e. are release insensitive.
5 tients with hereditary UC susceptibility are insensitive.
6 he best-studied receptors is BRASSINOSTEROID INSENSITIVE 1 (BRI1) in Arabidopsis (Arabidopsis thalian
8 r FLAGELLIN SENSING 2 (FLS2)-BRASSINOSTEROID INSENSITIVE 1-ASSOCIATED KINASE 1 (BAK1) complex, and in
9 on the plant protein kinase brassinosteroid insensitive 1-associated kinase 1 (BAK1) conformational
10 munity, Arabidopsis thaliana BRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 1 (BAK1) and so
11 activity of GSK3-like kinase BRASSINOSTEROID-INSENSITIVE 2 (BIN2), a key repressor of brassinosteroid
12 nknown biochemical activity, called ethylene-insensitive 2 (EIN2); and transcription factors such as
13 alpha/beta-fold hydrolase receptor KARRIKIN INSENSITIVE 2 (KAI2) and the F-box protein MORE AXILLARY
14 sion of an ethylene signaling gene, ETHYLENE INSENSITIVE 2 (ZmEIN2), co-segregated with a decreased s
15 w, winter-long upregulation of VERNALIZATION INSENSITIVE 3 (VIN3)(5-7), a PHD protein that functions
16 master transcriptionactivator EIN3 (Ethylene Insensitive 3)-mediated transcriptional activation plays
17 LEAFY COTYLEDON 1/2 (LEC1/2), ABSCISIC ACID INSENSITIVE 3, FUSCA 3 and WRINKLED 1 is upregulated in
20 responsive genes and the accumulation of ABA Insensitive 5 (ABI5), causing mutant plants with ABA-ins
21 educed transcript abundance of ABSCISIC ACID-INSENSITIVE 5 (ABI5), which encodes an activator of FLC
23 anescens) lines: wild type and abscisic acid-insensitive (abi1) with functionally impaired stomata.
25 ender a metalens achromatic and polarization-insensitive across nearly the entire visible spectrum fr
26 ding effect on the treatment of chemotherapy-insensitive aggressive B-cell non-Hodgkin lymphoma (B-NH
28 rridden in plants that contain a photoperiod-insensitive allele of Ppd-1, which hastens the completio
31 iagnosing bloodstream infections (BSIs), are insensitive and limited by prolonged time to results.
32 d bone scintigraphy, are recognized as being insensitive and nonspecific for response monitoring in a
33 strained heptamethine cyanine is temperature-insensitive and significantly extended at moderately ele
35 elf-adhesive, breathable, flexible, moisture-insensitive, and able to maintain their accuracy under s
39 s to compare the performance of arrival-time-insensitive (ATI) and arrival-time-sensitive (ATS) compu
41 (2+) chelation or overexpression of a Ca(2+)-insensitive CaM mutant, reduced coupling, which is consi
42 hibitory receptor expression, and interferon-insensitive CAR T cells enable combinatorial therapy wit
43 -complete responders of CC patients and CDDP-insensitive CC cell lines with CDDP-sensitive group.
44 f a T cell and show that checkpoint blockade-insensitive CD8 T cells can be induced to respond to che
46 ondary targeted approach to render otherwise insensitive cells, sensitive to a targeted therapeutic.
47 Heterologous expression of unc-7 in touch-insensitive chemosensory neurons confers ectopic touch s
48 n-sensitive rat TRPV1 (rTRPV1) and capsaicin-insensitive chicken TRPV1 (cTRPV1) exposed to a series o
50 specifically disrupted by deleting rapamycin-insensitive companion of target of rapamycin (Rictor), e
51 ion (TG) that includes Rictor, the rapamycin-insensitive complex-2 of mTOR (mTORC2), and genes involv
52 human mucosal epithelial cell types: insulin-insensitive corneal epithelial cells and insulin-sensiti
53 ht the possibility of developing photoperiod-insensitive crops by adjusting the allelic combination o
55 in-coated gelation films also show thickness-insensitive deep-blue emission with respect to the refer
56 ature or shade reduced the stability of a GA-insensitive DELLA allele in Arabidopsis thaliana Further
57 P1 enhanced the degradation of normal and GA-insensitive DELLA alleles when coexpressed in Nicotiana
63 a target of gibberellin receptor GIBBERELLIN INSENSITIVE DWARF1 (GID1)-promoted proteasomal destructi
68 d dosage responses than do putatively dosage-insensitive gene groups, suggesting that constraints on
73 , because spontaneous release becomes Ca(2+)-insensitive in Syb1(lew/lew)Syb2 (-/-) NMJs, our finding
74 res and soil moisture levels were remarkably insensitive in terms of their J(max25 degrees C) and V(c
75 Both receptors induced pertussis-toxin (PTX) insensitive inhibition of cyclic AMP (cAMP) levels in ma
77 me encodes three BEN-solo proteins including Insensitive (Insv), Elba1 and Elba2 that possess activit
78 mics: the charge relaxation time as a strain-insensitive intrinsic variable to measure absolute tempe
82 es, and that these neurons present direction-insensitive, linear voltage integration, suggesting they
83 ted inflorescence development of photoperiod-insensitive lines is promoted by advanced seasonal expre
84 chemical genetics screening to identify DFPM-insensitive loci by monitoring the activity of ABA-induc
86 cyte studies using the ubiquitous amantadine-insensitive M2 S31N variant, the current block showed fa
87 ly and affected the organization of estrogen-insensitive MCF10A cells in 3D collagen matrix by influe
88 l tissues, the corneal epithelium is insulin insensitive, meaning it does not require insulin for glu
91 ic airways disease (AAD) model and a steroid-insensitive model combining ovalbumin-induced AAD with C
93 ,5-triazine (RDX) have been updated with the insensitive munition (IM) 2,4-dinitroanisole (DNAN).
95 of 2,4-dinitroanisole (DNAN), a component of insensitive munitions formulations, by mineral-bound Fe(
96 (NTO) is one of the main ingredients of many insensitive munitions, which are being used as replaceme
97 AF2ER is an AF-2 disrupted estradiol (E2)-insensitive mutant ERalpha, but AF-1-dependent transcrip
98 ytes expressing wild-type SERCA2b or a redox-insensitive mutant in which C674 is replaced by serine (
104 Ion substitutions revealed that amiloride-insensitive NaCl responses depended on Cl(-) rather than
106 y polarization transfer (DEPT) and refocused insensitive nuclei enhanced by polarization transfer (RI
107 of these axons do not need to be temperature-insensitive or highly restricted, but coordinating the t
108 ated signaling pathways for survival and are insensitive, or rapidly evolve resistance, to selective
109 e presence of IL-4 to become potent, steroid-insensitive, pathogenic effector cells in asthmatic pati
111 cue the PIF4 level in addition to the thermo-insensitive phenotype of spaQ, suggesting that the SPA1
112 efore defining PGA as a potentially "steroid-insensitive" phenotype that requires exploration of alte
113 ive 5 (ABI5), causing mutant plants with ABA-insensitive phenotypes during seed germination and seedl
117 unders were minimized by using an arrhythmia-insensitive-rapid (AIR) cardiac T1 mapping pulse sequenc
118 receptor signaling but involves the CLAVATA3 INSENSITIVE RECEPTOR KINASE (CIK) family co-receptors, w
119 d an AAV vector that uses mutant "cross-over insensitive" recognition sites combined with an "ATG-out
121 sed mammalian or snake TRP channels in light-insensitive retinal cones in a mouse model of retinal de
122 ), a peptide ligand, and its receptors, RGF1 INSENSITIVEs (RGIs), a clade of five leucine-rich-repeat
123 zed by Na(+)-sensitive eticlopride and Na(+)-insensitive risperidone correspond to different degrees
125 erminant of taste transduction for amiloride-insensitive salt taste.SIGNIFICANCE STATEMENT Sodium and
126 KRAS(G12C) is maintained in its active, drug-insensitive state by epidermal growth factor receptor an
127 morphology and converts them into a nutrient insensitive state that is coupled to endoplasmic reticul
128 d also efficiently ablate the growth of drug-insensitive stem-like cells as well as therapy resistant
130 e bradycardia and AV block, but the atropine-insensitive tachycardia and PVCs were abolished by the b
132 ith the production of cold-induced and light-insensitive TIM isoforms facilitate EYA accumulation in
133 f stool remains the gold standard but can be insensitive, time-consuming, and difficult to maintain c
134 he potentiometric response of the MC3-ISM is insensitive to [Formula: see text] or changes in pH.
135 ome and demonstrate how dendritic spines are insensitive to a brief period of novel sensory experienc
136 nterestingly, jazD and jazD phyB plants were insensitive to a chemical inhibitor of Trp biosynthesis,
138 , we observe that certain capsid mutants are insensitive to a Nup62-mediated nuclear pore complex blo
139 d that myoblasts from the D2 background were insensitive to a specific small molecule inhibitor of DU
141 )] (i) Because catalytically-inactive BTK is insensitive to active-site BTK inhibitors, the mechanism
144 unctional in mood and anxiety disorders, are insensitive to alterations in area 14 activity as is the
145 1N) in the influenza A M2 channel renders it insensitive to amantadine (AMT) and rimantadine (RMT) bl
146 s arginine residue rendered mTORC1 signaling insensitive to amino acid starvation and are found frequ
147 e arousal-induced memory boosting effect was insensitive to amisulpride but was sensitive to proprano
149 orms constitutively active channels that are insensitive to ATP or the antagonist suramin, suggesting
156 ation site specific activity that is largely insensitive to changes in NMDA receptor-mediated neurotr
157 r to reversion for this adduct is relatively insensitive to changes in solvent while the adduct forme
158 emission rate (86 +/- 8 mug m(-2) h(-1)) was insensitive to changes in the ACH because its large indo
159 iscal characteristics of this MOF family are insensitive to changes in the metal cation, which enable
160 f cancers arise due to p53 mutations and are insensitive to chemotherapeutic treatments that activate
163 whereas ACC inhibition renders waiting times insensitive to confidence-modulating attributes of visua
164 +) release from an intracellular compartment insensitive to CPA; (iii) only Thg is able to activate C
165 f TYROSYL-DNA PHOSPHODIESTERASE 1 (TDP1) are insensitive to CPT, and only the wss1A tdp1 double mutan
166 formed at the top surface, which is not only insensitive to depth-dependent inhomogeneities but also
169 h superoxide (O(2) (*-)) production, must be insensitive to deuteration, and yields a predicted (16)O
172 udies suggest that viral genome packaging is insensitive to DNA sequence and fluctuations in packagin
175 of clinical rating scales; these scales are insensitive to early degenerative changes that underlie
176 -forming organic reactivity, were relatively insensitive to early drought conditions but decreased by
177 rs evolved (genetically or culturally) to be insensitive to efficacy because people tend not to rewar
178 that these variants render the eIF2B complex insensitive to eIF2 phosphorylation, which occurs under
179 -scales prior to burial in sediments and are insensitive to elevated (14)C concentrations following n
180 pressed functional KI GlyRs that were rather insensitive to ethanol when compared with WT GlyRs.
182 nd nuclear transitions(7), which are largely insensitive to external perturbations and reach waveleng
184 in HsSAS-6, whose substitutions rendered it insensitive to FBXW7-mediated degradation and control of
185 n addition, the ATN framework was relatively insensitive to frontotemporal lobar degeneration, and th
189 omosome-integrated native lac is shown to be insensitive to Gyrase overexpression, even at critically
190 as opposed to its pattern and amplitude, is insensitive to hydrogeological and nucleation parameters
192 thermophotovoltaic efficiency becomes nearly insensitive to increasing cell bandgap or decreasing emi
197 he membrane orientation of Ras is relatively insensitive to its bound guanine nucleotide and activati
201 iers: those for which the carrier density is insensitive to Li adsorption, and those whose density de
203 ol intoxication and reduced anxiety, and are insensitive to local manipulations of signaling in the B
205 In contrast, Lhb expression was relatively insensitive to loss of endogenous GnRH and continuous tr
206 rom the fou2 mutant, harboring TPC1 channels insensitive to luminal Ca(2+), can be excited fully by e
208 al and spin transitions that are first-order insensitive to magnetic field fluctuations, enabling opt
215 y on large and uncertain corrections and are insensitive to most of the Universe's volume and probabl
217 ASE4 (DGK4) grow slower and become partially insensitive to NO-dependent growth inhibition and re-ori
223 e compounds, in contrast to pyridomycin, are insensitive to overexpression of InhA in Mycobacterium t
224 stomatal reopening, and TARK1 OE plants were insensitive to P syringae pathovar tomato strain DC3118
225 that persons lacking functional Na(V)1.7 are insensitive to pain, has spurred considerable effort to
227 n is, unusually for RiPP biogenesis, largely insensitive to perturbations of the leader portion of th
231 three allelic pic30 mutants are selectively insensitive to picolinate herbicides, while pic30-3 is a
232 , we show that a memory selectivity bias was insensitive to propranolol but sensitive to amisulpride,
236 that the second phase of RhoA activation is insensitive to rapid turning off of the receptor and is
237 adrenergic receptors, respectively, and were insensitive to reverse-mode NCX blockade (KB-R7943).
238 activation of RagC and RagD GTPases, but is insensitive to RHEB activity induced by growth factors.
239 rom infant mice were predominantly immature, insensitive to RORgamma-inducing bacterial cues and to I
244 the histone H4 tail and appeared relatively insensitive to sequence differences on either side of th
246 ganoids lacking p53 mutation and p53 LOH are insensitive to SOAT1 loss, indicating a potential therap
247 e mechanism; it renders autoreactive B cells insensitive to stimulation by self-antigen, whereas Toll
248 e mass spectrometry, makes the gates largely insensitive to stoichiometric imbalances in the inputs,
252 after binding the poly(A) tail, PABP became insensitive to suppression by PAIPs and efficiently acti
253 ed integrated emissivity (epsilon(int) ), is insensitive to temperature (|depsilon(int) /dT| ~ 10(-4)
256 ope peak, which is a robust measure of mass, insensitive to the aforementioned natural and technical
259 entional imaging methods are destructive and insensitive to the buried device geometries, preventing
261 endogenous phosp27-CDK4-CycD1 complexes were insensitive to the CDK4-targeting drug palbociclib.
264 concentration of an active CaM-binding TF is insensitive to the concentration of any other CaM-bindin
265 r is a fundamental physical feature which is insensitive to the details of the network generation.
266 ults of biodiversity experiments are largely insensitive to the exclusion of unrealistic communities
268 vels than the peripheral rate-place code and insensitive to the harmonic relationships among frequenc
269 377V/V388I mutant or SALL4 G416A mutant were insensitive to the inhibitory effects of thalidomide, le
270 text] This energy partition is approximately insensitive to the ion-to-electron temperature ratio [Fo
271 h autobiographical recall periods (which are insensitive to the moment-to-moment content of retrieval
272 GAT107, and B-973B responses were relatively insensitive to the noncompetitive antagonist mecamylamin
273 d that accuracy and precision are relatively insensitive to the number of replicated assignments for
274 from mice of either sex, an effect that was insensitive to the PKA inhibitors (H-89, KT270) but that
279 show that most polyspermy-derived seeds are insensitive to the triploid block suppressor admetos.
280 a small safe operating space exists that is insensitive to the type of policy implementation, while
282 ar features, malignant clones are frequently insensitive to traditional AML chemotherapeutic agents.
284 Whereas the behavior of CYP 19A1 was rather insensitive to truncation of the TM-helix, mutations in
285 tosol avoid inflammasomes(1-6) and are often insensitive to type I interferons (IFN-I), but are restr
290 erence ligand and produces a ranking that is insensitive to variations in the concentration of indivi
291 are able to maneuver through narrow spaces, insensitive to wall-targeting antibiotics, and capable o
292 However, this intramembrane enzyme becomes insensitive to warfarin inhibition in vitro, preventing
293 it is information-rich, minimally invasive, insensitive to water background and requires little to n
294 mixed with wild-type tumor cells, IFN-gamma-insensitive tumor cells indeed grow out, which depends u
295 erefore mediated by the MCRC but becomes RAP-insensitive under DFO treatment, with concomitantly decr
296 , GPR65, and GPR68 pH sensing and provide pH-insensitive variants that should be valuable for assessi
297 requires diacylglycerol (DAG) but is Ca(2+) -insensitive, which are characteristics of the novel grou
298 found that Phi6 RdRp is largely temperature insensitive, while PV and HRV-C RdRps replication kineti
300 thyl ether); and (5) the reaction is largely insensitive with respect to common hydrosilane reductant