ライフサイエンスコーパス: insensitivity

1 onstrated that Rg1 attenuated UVB-induced GC insensitivity.

2 and also reversed CSE-induced corticosteroid insensitivity.

3 he presence of a water molecule which ensure insensitivity.

4 may, in turn, contribute to further steroid insensitivity.

5 ion being associated with relative abatacept insensitivity.

6 ing from neuropathic pain to congenital pain insensitivity.

7 that could be responsible for glucocorticoid insensitivity.

8 4%) and show glucose intolerance and insulin insensitivity.

9 fundamentally restricted due to its inherent insensitivity.

10 eus to cooperate with tubulin towards taxane insensitivity.

11 besity arises as a result of leptin receptor insensitivity.

12 eased HAT activity generating glucocorticoid insensitivity.

13 ring oxidative stress-induced glucocorticoid insensitivity.

14 ion mutation in PRLR, resulting in prolactin insensitivity.

15 , clinically characterized by glucocorticoid insensitivity.

16 ize type-B ARR proteins leading to cytokinin insensitivity.

17 s growth attenuation and growth hormone (GH) insensitivity.

18 ing to C. glabrata may be the reason for its insensitivity.

19 resistant pathways using our ASM model of GC insensitivity.

20 ds, and oxidative stress contributes to this insensitivity.

21 utation, R405S, that caused partial androgen insensitivity.

22 s of acute G(q) signaling and also of leptin insensitivity.

23 y cultivation as a result of its photoperiod insensitivity.

24 d for SSCs exhibit catabolism-independent RA insensitivity.

25 ed how Na(V)1.7 mutations lead to human pain insensitivity.

26 cellular Ca(2+) and inducing cellular Ca(2+) insensitivity.

27 ium channel Na(v)1.7, that accompany algogen insensitivity.

28 , sympathetic activation, and glucocorticoid insensitivity.

29 mbines tunability of the coupling with noise insensitivity.

30 -mediated inflammation and/or corticosteroid insensitivity.

31 ms of these DDTs was associated with insulin insensitivity (-0.38 Matsuda index, p = 0.001), increase

32 variation at CRY2 underlies this temperature insensitivity across several traits.

33 ese changes correlate with early temperature insensitivity and a later-onset decline in motor perform

34 Insulin insensitivity and adipokine abnormalities (the hallmarks

35 ouble mutant that exhibits complete ethylene insensitivity and confirms that these two genes act redu

36 activity, and noxy2-2, which shows oxylipin insensitivity and mitochondrial dysfunction.

37 levated p K(a) value (5.85) for affording pH-insensitivity and optimal contrast upon designed use.

38 for further investigative areas into insulin insensitivity and type 2 diabetes.

39 but important differences in signaling, drug insensitivity, and other key cellular processes amongst

40 The mechanisms of corticosteroid insensitivity are also determined.

41 nd the molecular mechanisms behind progestin insensitivity are poorly understood.

42 ure and the molecular basis of its rapamycin insensitivity are unknown.

43 ration movements, running vigor, and outcome insensitivity) are quite closely linked together.

44 ycemic clamp conditions, eliminating insulin insensitivity as a possible protective mechanism.

45 about the validity of structure sensitivity/insensitivity at the bottom of the catalyst size range.

46 bstruction, and the notion of corticosteroid insensitivity because potential targets for treatment ha

47 ly, lower BCR-ABL levels may indeed cause IM insensitivity, because primary murine bone marrow cells

48 HSAN V patients present with congenital pain insensitivity, but are cognitively normal.

49 four previously unknown instances of algogen-insensitivity by screening eight African rodent species

50 obiota induced greater adiposity and insulin insensitivity compared to T1.

51 n phytochrome A and additively increases ABA insensitivity conferred by the abi2, abi4, and abi5 muta

52 alpha-Amanitin insensitivity confirmed that overexpression of miR-4443

53 g, whereas TOC1 overexpression causes thermo insensitivity, demonstrating that TOC1 mediates the even

54 This insensitivity derives from compensatory changes to the p

55 This neurosteroid insensitivity did not primarily result from perturbation

56 By contrast, mutations that confer ABA insensitivity did not promote defense responses at high

57 comprehensive assessment of congenital pain insensitivity due to Na(V)1.7 loss of function.

58 ucture sensitivity, in contrast to structure insensitivity found for larger particles.

59 gnaling has been connected to cancer, and GH insensitivity has been reported in cachexia patients.

60 corticosteroid (CS) therapy, and relative CS insensitivity has been shown in airway smooth muscle cel

61 the basal ganglia to the control of outcome insensitivity (i.e., habit) and behavioral vigor (i.e.,

62 ence of directional selection for glyphosate insensitivity in advance of reports of field resistance.

63 tion represents a novel mechanism driving GC insensitivity in ASM in severe asthma.

64 endotoxin might contribute to corticosteroid insensitivity in asthmatic patients.

65 endotoxin might contribute to corticosteroid insensitivity in asthmatic patients.

66 ntrations are associated with corticosteroid insensitivity in asthmatic patients.

67 egulation is thought to cause glucocorticoid insensitivity in COPD.

68 alpha and FOXM1 contributes to anti-estrogen insensitivity in ER(+) breast cancer.

69 tion mutation at alpha53, may lead to HLA-DM insensitivity in HLA-DQ2.5.

70 n this work, we have analyzed glucocorticoid insensitivity in human pulmonary artery endothelial cell

71 fied pAKT and pERK phospho-heterogeneity and insensitivity in individual leukemia cells treated with

72 The mechanisms driving glucocorticoid (GC) insensitivity in patients with severe asthma are still u

73 vity may contribute to both relative steroid insensitivity in patients with severe eosinophilic asthm

74 To uncover key mechanisms of docetaxel insensitivity in prostate cancer, we have established do

75 rotonus, linear integration, and directional insensitivity in STG neurons arise from their neurite ge

76 ite contributing little to cardiac glycoside-insensitivity in vitro, A119S, like substitutions at 111

77 al cortex activity to win may reflect reward insensitivity in youth with disruptive behavior disorder

78 Whilst cytokines can induce corticosteroid insensitivity in-vitro, how current and former smoking a

79 Structure insensitivity, inherent for specific cluster sizes, is i

80 We show that punishment insensitivity is a unique phenotype, unrelated to differ

81 rather than a single molecule, odor-specific insensitivity is averaged out, and the test accurately d

82 zyme from Agrobacterium strain CP4, in which insensitivity is conferred by an active site alanine.

83 This TNKSi insensitivity is conferred by beta-catenin's association

84 The latter properties and V7's oxygen insensitivity make V7 a very promising candidate to repl

85 These findings suggest that reward insensitivity may be a contributory mechanism to apathy

86 nnel subunits tested, suggesting target site insensitivity may not be important in our hop T. urticae

87 We hypothesized that this insensitivity may result from insufficient generation of

88 d in C. elegans in genetic screens for touch insensitivity (MEC-2(P134S)).

89 of phages and mechanisms of mutational phage insensitivity must be characterized for rational design

90 Increased body mass and insulin insensitivity occurred in response to HFD feeding irresp

91 remains unknown how metformin resistance or insensitivity occurs.

92 expression suppressed the brassinazole (BRZ) insensitivity of BIN2 triple mutant bin2 bil1 bil2, and

93 likely related to proteomic heterogeneity or insensitivity of cancer cells to DNA-repair inhibition.

94 Insensitivity of CCNE1-amplified tumors to platinum cros

95 These findings coupled with the known insensitivity of CD8(+) T cells to corticosteroids sugge

96 The insensitivity of cells to ISRIB during acute ISR may exp

97 been a longstanding challenge because of the insensitivity of conventional detection methods.

98 tral effects of inflammation are hindered by insensitivity of conventional structural magnetic resona

99 atin filament association and fosters Ca(2+) insensitivity of desmosomes in keratinocytes, presumably

100 may give rise to their damage tolerance and insensitivity of failure to the presence of flaws even w

101 The insensitivity of Fe(0) corrosion to proteinase K treatme

102 6 showed a modified immune response, and the insensitivity of g6pd6 mutant plants to PAMP-induced gro

103 rved in all CAT isoforms did not lead to NEM insensitivity of hCAT-2A.

104 Due to the insensitivity of human eyes to the polarization and phas

105 The apparent insensitivity of lambda N to crowding may also be due in

106 Given the relative insensitivity of line width to PEG size, we anticipate t

107 This insensitivity of local barrier crossing to solvent frict

108 tic center promises to overcome the inherent insensitivity of magnetic resonance.

109 ty and early type 2 diabetes, as a result of insensitivity of metabolic tissues to the effects of ins

110 to find coding of modality is not driven by insensitivity of multivariate pattern analysis in these

111 The CAi insensitivity of NHE flux suggests that, in the native c

112 e differences that might underlie the proton insensitivity of nmrASIC3.

113 l mechanism that contributes to the relative insensitivity of non-image-forming behaviors at low ligh

114 the 18:1-synthesizing gene SUPPRESSOR OF SA INSENSITIVITY OF npr1-5 (SSI2) or exogenous application

115 The insensitivity of photosynthetic parameters to warming co

116 The insensitivity of primary production to temperature is sh

117 The main limitations of this study are the insensitivity of reservoir measurements, and the fact th

118 uld be due to a considerable placebo effect; insensitivity of scales to quantify stiffness, especiall

119 cotine status in HCS but not SCZ, suggesting insensitivity of SCZ to nicotine-derived performance ben

120 e 2 mechanisms cannot be clarified given the insensitivity of serum zinc to identify subclinical defi

121 aB-dependent gene promoters, may underlie CS insensitivity of severe asthma.

122 advantages over traditional SPR in terms of insensitivity of signal responses to pH and salinity, le

123 n various crystal symmetries, suggesting the insensitivity of skyrmions to the underlying crystal lat

124 tion between the radicals, rationalizing the insensitivity of the bonding interaction to substituents

125 An intriguing insensitivity of the droplet shape toward surface hetero

126 The relative insensitivity of the method to the instrumental complian

127 omplexity of these molecules, as well as the insensitivity of the method.

128 er decoupling is further demonstrated by the insensitivity of the optical absorption and Raman spectr

129 of Pt(111), in line with the known structure insensitivity of the reaction.

130 This result is in contrast to the insensitivity of the transition temperature to magnetic

131 However, intrinsic resistance (i.e., insensitivity of the tumors to therapy) remains a daunti

132 In all instances we demonstrate insensitivity of the whole-genome 3D reconstruction obta

133 rt-read sequencing is challenging due to the insensitivity of these platforms to transcripts isoforms

134 However, the relative insensitivity of this genotype to most protease inhibito

135 olding of a helix-containing protein, is the insensitivity of torsion angle isomerization to solvent

136 ith spirometry only because of the risks and insensitivity of transbronchial biopsy for detecting ACR

137 The relative temperature insensitivity of VEGF secretion and its Sar1 and Arf1 in

138 (PDF) studies have been used to overcome the insensitivity of X-ray diffraction data to different tra

139 The sensitivity, or insensitivity, of catalysed reactions to catalyst struct

140 s to increased demand for control, including insensitivities or lags in fully activating the cognitiv

141 annels, including disorders characterized by insensitivity or reduced sensitivity to pain and others

142 with these disorders exhibit glucocorticoid insensitivity or resistance.

143 -0.19 EU/mL], P = .042) unrelated to steroid insensitivity or serum cytokine concentrations.

144 In parallel, we showed that stomatal CO2-insensitivity phenotypes of a mutant cis (CO2-insensitiv

145 itivity, more open stomata, and stomatal CO2-insensitivity phenotypes of the Arabidopsis thaliana acc

146 ironments require varieties with photoperiod insensitivity (PI) that can flower in short days.

147 gus pathogenesis, which, by reversing Ca(2+) insensitivity, promotes Dsg3 depletion.

148 , sympathetic activation, and glucocorticoid insensitivity: respectively, nuclear factor kappa B (NF-

149 Target site insensitivity resulting from point mutations within the

150 Naturally occurring pheromone insensitivity results in part from previously described

151 o explore ENZ properties such as environment insensitivity, super-coupling, and surface avoidance.

152 905 androgen insensitivity syndrome (AIS)-associated loss-of-function

153 Moreover, AR mutants in complete androgen insensitivity syndrome (CAIS) tend to have a greater eff

154 cluding from patients with complete androgen insensitivity syndrome (CAIS).

155 Androgen insensitivity syndrome in its complete form is a disorde

156 ighlights a molecular mechanism for estrogen insensitivity syndrome involving mutations that perturb

157 identified in a female patient with estrogen insensitivity syndrome.

158 isrupting AR function in males with androgen insensitivity syndrome.

159 izing mutations associated with the androgen insensitivity syndrome: Pro767Ala, Phe765Leu, Met743Val

160 highlighting a molecular switch for chloride insensitivity that is transduced through an arginine fli

161 of neutrophilic airway inflammation, steroid insensitivity, the epithelial cell profile, and airway r

162 Thus, we hypothesized that FGF21 causes GH insensitivity through regulation of LEPROT and/or LEPROT

163 f hippocampal CA1 neurons and anhedonic-like insensitivity to a sucrose solution also persisted despi

164 and drought stress in addition to conferring insensitivity to ABA.

165 tebrate to show physiological and behavioral insensitivity to acid pain in the skin.

166 High thermal stability and insensitivity to aggregation-induced luminescence quench

167 he reaction features a high substrate scope, insensitivity to air, and excellent product yielding.

168 as the reference electrode, because of their insensitivity to air, when compared to lithium.

169 These transgenic mice also show selective insensitivity to alcohol-aversion and increased novelty-

170 Further, the insensitivity to alcohol-aversion exhibited by male mice

171 Insensitivity to antagonist addition in a real-time, lab

172 has been proposed to contribute to acquired insensitivity to anti-epileptic drugs exhibited by Nav c

173 nd has been implicated in the development of insensitivity to anti-estrogen therapy.

174 iation of ATP responses by ginsenosides, and insensitivity to ATP(-) or ATP(+) ginsenoside-induced ce

175 ndrial membrane potential (Deltapsi(m)), and insensitivity to bax-gene deletion, (2) underwent excito

176 rangement, speed of measurement and relative insensitivity to beam movements.

177 ism also exhibits high linearity, as well as insensitivity to bending and twisting deformations-featu

178 by applying magnetic fields, and pronounced insensitivity to both particle chemistry and harsh proce

179 ss (varphif =14.4 % at 150 mM of K(+) ), and insensitivity to both pH in the range 5.5-9.0 and other

180 he gain-of-function mutant, bin2-1, exhibits insensitivity to BR-induced de-greening and reduced numb

181 Target site insensitivity to cardenolides is a prime candidate for s

182 he path conferred resistance and target-site insensitivity to cardiac glycosides(16), culminating in

183 Despite its insensitivity to changes in functional residual capacity

184 ential injurious effects of respiratory rate insensitivity to chemical feedback during assisted venti

185 Chemoresistance, i.e., tumor insensitivity to chemotherapy, shortens life expectancy

186 In addition, its relative insensitivity to cholesterol depletion suggests that the

187 , a lengthened and delayed circadian rhythm, insensitivity to clock-resetting morning light, and heig

188 Despite its insensitivity to cold, TRPV1 enhances membrane potential

189 d might be inherently inefficient due to its insensitivity to context-dependent effects.

190 ortex,which in turn predicted the behavioral insensitivity to contingency change.

191 onse associations, or a compulsion driven by insensitivity to costs imposed on drug seeking.

192 he association with economic demand) than by insensitivity to costs.

193 Disruption of the CRFs results in partially insensitivity to cytokinin in a root elongation assay an

194 ed d-Amphetamine-induced locomotor activity, insensitivity to d-Amphetamine potentiation of ICSS thre

195 A potential reason for gamma-conglutin insensitivity to digestion may be related to the fact th

196 e verified as true NP binding sites based on insensitivity to DNA antisense oligonucleotide-mediated

197 ng at double notches, despite their apparent insensitivity to DW chirality.

198 ideology, in engendering Americans' relative insensitivity to economic inequality.

199 Cells with acquired insensitivity to either folate or cAMP remain fully resp

200 function may therefore result in epithelial insensitivity to electric fields and contribute to KS di

201 Insensitivity to endocytosis inhibitors and classical st

202 subpopulation of C4-2B cells that developed insensitivity to ENZA after sustained exposure in cultur

203 ECTA-LIKE1 (ERL1) signaling confers specific insensitivity to EPF2 and EPF1, respectively.

204 lopment and defects in BIG or ARF1 result in insensitivity to ethylene.

205 THIK1, including inhibition by halothane and insensitivity to extracellular pH variations.

206 ice show altered beta1-integrin activity and insensitivity to Fgf2.

207 Evolved HPPD enzymes showed insensitivity to five inhibitor herbicides.

208 f activation, a reduced current density, and insensitivity to gating modulation by Ca(2+)-CaM.

209 binding sites in the amygdala and behavioral insensitivity to ghrelin receptor agonism.

210 EPSPSs with high catalytic efficiency and insensitivity to glyphosate are of microbial origin, inc

211 Basal increases in cytosolic Ca(2+) and insensitivity to H2O2-mediated Ca(2+) entry in DeltakatG

212 s exhibit an inherent and severe ventilatory insensitivity to hypercapnia but also exhibit relatively

213 e tested the hypothesis that the ventilatory insensitivity to hypercapnia in BN rats is due to altere

214 Although they are associated with insensitivity to ibrutinib, lesions in the alternative N

215 fects on Treg sensitivity versus CD8(+) Teff insensitivity to idelalisib could still potentially be e

216 ow BCR-ABL expression that may explain their insensitivity to IM and their low propensity to develop

217 d with inhaled steroids, suggesting relative insensitivity to inhibition by corticosteroids.

218 immaturity was due to spatial limitations or insensitivity to interocular correlation, highly suprath

219 1%) of 41 studied noxy mutants have an added insensitivity to isoxaben, an herbicide inhibiting cellu

220 k of response to interferon gamma, including insensitivity to its antiproliferative effects on cancer

221 We argue that perceptual insensitivity to large moving stimuli effectively implem

222 bit unrealistic oscillatory behavior and SOC insensitivity to long-term changes in C inputs.

223 limits of traditional strategies and exhibit insensitivity to lossy tissue environments.

224 Insensitivity to low SMN emerged abruptly at postnatal d

225 r1 knockout mice consume more MA and exhibit insensitivity to MA-induced CTA and hypothermia, compare

226 lective fluctuations, and the simplicity and insensitivity to material details of the 'normal' state

227 ighly metastatic population shows a relative insensitivity to matrix stiffness suggesting adoption of

228 deficits were not caused by perseveration or insensitivity to negative feedback though.

229 These findings indicate that insensitivity to negative information may be a key compo

230 ical power to model rare taxa and/or species insensitivity to neighbours.

231 to excessive production of ADCY1 protein and insensitivity to neuronal stimulation.

232 Insensitivity to NLP cytolysins of monocot plants may be

233 utosomal recessive disorder characterized by insensitivity to noxious stimuli and variable intellectu

234 Congenital insensitivity to pain (CIP) or congenital analgesia is a

235 from studies of individuals with congenital insensitivity to pain (CIP).

236 ns in SCN9A are known to underlie congenital insensitivity to pain (CIP).

237 n SCN9A have been reported in (1) congenital insensitivity to pain (CIP); (2) primary erythromelalgia

238 ction mutations in Na(V)1.7 cause congenital insensitivity to pain (CIP); this voltage-gated sodium c

239 gated sodium channel Nav1.7 cause congenital insensitivity to pain in humans and mice.

240 w that JNJ63955918 induces a pharmacological insensitivity to pain that closely recapitulates key fea

241 Congenital insensitivity to pain with anhidrosis (CIPA) is a rare a

242 Congenital insensitivity to pain with anhidrosis (CIPA) is caused b

243 cessive disorder characterized by congenital insensitivity to pain, inability to feel touch, and cogn

244 ted with episodic extreme pain disorders and insensitivity to pain, respectively.

245 ead to small-fibre neuropathy and congenital insensitivity to pain, respectively.

246 , which encodes Nav1.7, result in congenital insensitivity to pain, whereas gain-of-function mutation

247 of function mutations results in congenital insensitivity to pain.

248 underlies a human disorder characterized by insensitivity to pain.

249 .9 mutation (L1302F) that is associated with insensitivity to pain.

250 e depolarizations cause hypoexcitability and insensitivity to pain.

251 n, survival or proliferation, yet timing and insensitivity to park mutation suggest that preferential

252 h dynamic range, good signal-to-noise ratio, insensitivity to pH and Mg(2+), tunable Ca(2+) affinity,

253 cross sections (150 GM) at nearly 720 nm and insensitivity to pH within the biologically relevant pH

254 horetic mobility (EPM) of GONPs indicated an insensitivity to pH, although IS did play a role.

255 ive to reproductive growth, as well as their insensitivity to photoperiod, establish a dual role for

256 nfirmed sensor oxidation by H(2) O(2) , show insensitivity to physiological pH changes, and demonstra

257 er ions (e.g., Mg(2+), Ca(2+), K(+)) and its insensitivity to potential changes in pH, this sensor is

258 our results from excessive focus on rewards, insensitivity to punishment, or to dysfunction in a part

259 ith indolent behavior, local recurrence, and insensitivity to radiotherapy and chemotherapy.

260 g of RALF to FERONIA and reduced binding and insensitivity to RALF-induced growth inhibition in feron

261 tation to changes in natural visual input or insensitivity to rapid changes in visual drive.

262 lysis, slowed-down forward translocation and insensitivity to regulatory pauses.

263 on partially ameliorating dependence-related insensitivity to reinforcing outcomes/'liking', but havi

264 Here we investigated if insensitivity to reward might be a contributory factor a

265 However, the molecular basis of SCN CC insensitivity to RF and its possible pathological conseq

266 Rather than revealing insensitivity to rising inequality, the results suggest

267 ants with NRB4 null alleles express profound insensitivity to SA, even more than npr1.

268 P6, and ZFP7 zinc finger factors confers ABA insensitivity to seed germination, while the zfp3 zfp4 d

269 l tracking involves repeated refractoriness (insensitivity to sensory information for a certain durat

270 incurs substantial, serial, refractoriness (insensitivity to sensory information of 350 and 550 ms f

271 bility to identify poor performers, relative insensitivity to severity adjustment, and the ability to

272 ia has been thought to arise from alpha-cell insensitivity to suppressive effects of glucose and insu

273 Further, our approach can inherit insensitivity to system preparation and measurement erro

274 failed for nearly half of the species due to insensitivity to temperature change at To .

275 alcohol-drinking, which reflects a selective insensitivity to the aversive properties of alcohol into

276 nd that the Elongator (ELP) complex mediates insensitivity to the EGFR inhibitor erlotinib in TNBC ce

277 teins recycle constitutively and demonstrate insensitivity to the endocytic effects of AMPH and PKC (

278 autism spectrum disorders (ASDs) often show insensitivity to the human voice, a deficit that is thou

279 zation, extremely long depolarization times, insensitivity to the in vivo environment or particle tum

280 displayed very low activities and a dramatic insensitivity to the lipid substrate.

281 looking in autism is consistent with passive insensitivity to the social signals in others' eyes.

282 t advantage of the proposed technique is its insensitivity to the thermal interfacial impedance and i

283 This new technique has great advantages of insensitivity to thermal effects, the bias current, and

284 However, insensitivity to these chemotherapeutic agents including

285 study's aim was to examine potential neural insensitivity to these effects of hunger in anorexia ner

286 The lack of moving parts and insensitivity to vibration allow for lower noise and imp

287 vity of GABA-evoked currents to diazepam and insensitivity to Zn(2+), together with the weak direct a

288 mind (modularity, reflexiveness, and context-insensitivity) to argue cognition does not fundamentally

289 Thanks to the penetrating properties and the insensitivity toward the electric conduction properties

290 hage (phiCr30), and the loss of HvyA confers insensitivity towards phiCr30.

291 with second-line treatments targeting innate insensitivity, up to 100% of mice that would have otherw

292 This action drives GC insensitivity via protein phosphatase 5-dependent impair

293 mata opening, enhanced leaf cooling, and ABA insensitivity was conserved with OsRZFP34 expression.

294 Glucocorticosteroid insensitivity was selective for proinflammatory cytokine

295 inked to either cold-aggravated pain or pain insensitivity, we propose a model in which the physiolog

296 r tests to identify patterns of response and insensitivity were performed when tissue was available.

297 e the development of age-dependent quercetin insensitivity when continued supplementation fails to dr

298 , a consequence of del(8p), results in TRAIL insensitivity, which may contribute to ibrutinib resista

299 sociated with increased appetite and insulin insensitivity, while chronically sleep-deprived individu

300 -gated sodium channel Na(v)1.7 leads to pain insensitivity without deficits in the central nervous sy