ライフサイエンスコーパス: insight

1 black boxes with limited human-interpretable insight.

2 erspectives based on emerging techniques and insights.

3 l development, this study provides important insights.

4 es, can be used to generate novel biological insights.

5 generally expanding to incorporate these new insights.

6 ovel causal associations providing important insights about the cause of these diseases, which can he

7 Recent studies have provided exciting insights about the unique characteristics of skin-reside

8 diabetes is an important approach to gaining insight and suggest that an insulin sensitizer may allev

9 half-lives with (18)F-FDG, revealed biologic insight and supported the ability to track biologic proc

10 goals are to provide a means of deriving new insights and infection control strategies based on the d

11 copic monitoring techniques provide detailed insights and unexpected findings for the unique reaction

12 ensions of well-being-awareness, connection, insight, and purpose.

13 ve CYP3A5 inhibition, along with mechanistic insights, and highlight clobetasol as an important chemi

14 location-specific, the approach and overall insights are generalizable.

15 81's function as a molecular scaffold; these insights are relevant to CD81's varied roles in both hea

16 These mechanistic insights assisted the discovery of a new Ti(salen) catal

17 These insights contribute to the ongoing search for ultrastron

18 These valuable insights create enormous opportunities in diverse applic

19 These mechanistic insights delineate the scope and limitations of S1-chape

20 in silico investigation yielded mechanistic insights; e.g., through simulations, bepridil's more pro

21 this work demonstrates in-depth mechanistic insights employing electrochemistry, which suggests a st

22 The mechanistic insights enabled development of an electrochemically dri

23 This mechanistic insight, enabled by microsecond-timescale MD simulations

24 rationale for epitope conservation, provide insights for development of more universal SARS-like cor

25 Our findings will provide important insights for selecting fractionated regimens during radi

26 These results bring new insights for studies with venom compounds, PIs, and drug

27 e a protease's substrate recognition, giving insights for the potential prediction of novel substrate

28 king endogenous proteins, this work provides insights for understanding and manipulating inter-organe

29 In this review, we connect insights from cognitive neuroscience and psychiatry to s

30 Early insights from laboratory studies and research on related

31 Recently, researchers have begun to leverage insights from regenerating and metamorphosing organisms,

32 aisal of scientific literature; (2) clinical insights from the HAWK and HARRIER trials, postmarketing

33 spects for emerging methodologies to further insights gained from past climates.

34 Furthermore, mechanistic insights have been revealed by demonstrating that for AB

35 These findings resulted in a profound insight in in vitro gastric molecular lipolysis mechanis

36 onmodel systems promises to provide exciting insights in the years to come.

37 at the molecular level can provide valuable insights in understanding intrinsic reaction pathways, f

38 rizing these algorithms has led to important insights, including the discovery of guidance rules that

39 These insights indicate the outstanding promise of delocalized

40 Our result offer insight into a key step in substrate ubiquitination by a

41 In summary, this study provides novel insight into a possible mechanism for CBD interactions w

42 spectra obtained allowed us to gain further insight into accurate identification, concluding that th

43 ding into vaccine design and offer important insight into B cell fate decisions.

44 d neutrophil number or function, and provide insight into basic mechanisms of neutrophil biology.

45 These findings suggest that lower insight into bodily signals is linked to urges to move t

46 iatric symptoms to brain networks, providing insight into brain-behaviour relationships in patients w

47 IM) is a key technology that provides direct insight into cell metabolism, cell dynamics and protein

48 nts following MHV68 infection should provide insight into core elements of SINE regulation, as well a

49 ty, while offering an opportunity for better insight into CPA formation via the implementation of sem

50 ent a challenging but valuable model to gain insight into CTL biology.

51 Tape strips provide insight into disease pathomechanisms and cutaneous disea

52 Our study provides critical insight into drivers of key flowering phenophases and co

53 substrate-derived inhibitors, which provide insight into dynamic loop movements that occur on substr

54 a clinical setting and offer groundbreaking insight into future development of cellular immunotherap

55 these data not only provide new mechanistic insight into how a unique collagen fragment may regulate

56 r-independent Argonaute pathways and provide insight into how cells and viruses use a conserved RNA p

57 computational analysis provide unprecedented insight into how different DNA sequences select distinct

58 l culture and in vivo This work provides new insight into how flaviviruses control pathogenesis and m

59 Our work provides insight into how nuclei and spatial system dimensions ca

60 in the nutrient stress response and provide insight into how nutrient depletion might influence PDAC

61 trophils and S. aureus biofilms and provides insight into how S. aureus evades the neutrophil respons

62 of free hydroxyl groups in cutin and provide insight into how the mutations affect the esterification

63 rol disease in livestock, but we have little insight into how this impacts antimicrobial resistance (

64 es in at-risk populations that have provided insight into immune responses during acute infection, in

65 - are found particularly useful in providing insight into inter-decadal GDP variability over this per

66 t human neutrophils from injury and provides insight into its mode of action beyond a basic antibioti

67 ing these processes, we can start to provide insight into manipulation of these regulatory pathways t

68 cell level in humans and rodents provide new insight into microglia-astrocyte communication in homeos

69 This approach provides greater insight into multifunctional sutures with inherent sensi

70 TM accumulation in obese AT, lending further insight into obesity-related comorbidities in humans.

71 an exercise and clock interaction, providing insight into potential mechanisms of exercise-induced ph

72 Our study provides a mechanistic insight into saliva-aided viral transmission and could o

73 These data provide unprecedented insight into some of the processes by which cognition ev

74 This study offers new insight into supramolecular polymers composed of custom-

75 These findings provide insight into the affinity maturation process and potenti

76 The obtained insight into the Ag species dispersion will benefit futu

77 Our work provides insight into the assembly mechanism of these bacterial o

78 Despite the diversity in function, basic insight into the assembly of well-defined amphiphilic po

79 Biophysical insight into the binding interaction between the major w

80 etic resonance spectroscopy that may provide insight into the biological behaviour of various bone tu

81 ry sequences, but they have provided limited insight into the biology of regulatory elements due to t

82 oth nonimmune and alloimmune, to gain better insight into the causes of graft failure.

83 Together, these findings provide insight into the cellular basis of islet development.

84 rate widespread pleiotropy and offer further insight into the complex genetic architecture of cross-c

85 functional materials, providing fundamental insight into the deformation process of the involved mat

86 etabolic and phenotypic variation, providing insight into the difficulties in choosing the correct co

87 Collectively, our findings provide insight into the disease mechanism of Wolfram syndrome a

88 Furthermore, our results provide further insight into the effect of guanidine hydrochloride (GdnH

89 etworks from data, but also provide a unique insight into the elusive functional and structural drive

90 studies on triglyceride metabolism, to gain insight into the genes and physiological mechanisms that

91 cterize the natural history of DCM, provides insight into the host immunologic response, and has dire

92 orated the experimental results and provided insight into the host-guest binding mode.

93 To get a deeper insight into the imine bond dynamics of covalent organic

94 This study provides an in-depth insight into the impact of sugar reduction reformulation

95 Improved insight into the inheritance patterns, arrhythmic risks,

96 igatus Together, these data provide critical insight into the initial epithelial host response to Asp

97 Several studies provide insight into the landscape of breast cancer genomics wit

98 s from 1,738 young healthy adults, providing insight into the lifetime impact of SVD genetic risk.

99 Molecular dynamics provide atomic-level insight into the loop configurations.

100 om reward delivery to cue onset, and provide insight into the maladaptive nature of memory.

101 t difference in current magnitude, providing insight into the mechanism that produces rhythmic action

102 heir sensory and motor properties, providing insight into the mechanisms underlying enhanced sensory

103 This study provides a new insight into the metabolism of IVD cells under nutrient

104 urates and steroid anesthetics have provided insight into the modes of action of these drugs on the G

105 is study provides for the first time a novel insight into the molecular basis of sinonasal mucociliar

106 Our results provide insight into the molecular mechanism of drug export and

107 To gain insight into the molecular mechanisms and determinants o

108 lved in SCD pathogenesis and provide further insight into the multifaceted effects of HU treatment.

109 This study provides insight into the neural dynamics producing vestibulocoll

110 Our results offer new insight into the normal function of PC2 as a ubiquitous

111 These findings provide mechanistic insight into the opposing functional effects produced by

112 relatives of vertebrates, tunicates promise insight into the organization and evolution of vertebrat

113 nd characterize enset landraces while giving insight into the organization of the genome.

114 summarized in a far-IR map, in order to gain insight into the origin of the far-IR localized and delo

115 These results offer insight into the pathogenesis of scarlet fever-causing G

116 ce of energy homeostasis, thus providing new insight into the pathophysiology of metabolic disease.

117 stability of p53/DNA complexes, and provide insight into the pathways by which those complexes assem

118 lve a long-standing problem, providing a new insight into the physics of magnon Bose-Einstein condens

119 Access to this information provides insight into the physiological responses that result fro

120 ent approaches, which has provided important insight into the population dynamics of TEs.

121 This review also provides an insight into the prevailing trends and the future of env

122 nscriptomic analyses of the shoot apex yield insight into the processes of stem-cell function and cel

123 ations at various levels of theory to obtain insight into the properties of molecular nitric acid at

124 n during sorghum internode growth, providing insight into the regulation of monocot stem development.

125 ework combined with multiscale data gives us insight into the relative roles of variation from differ

126 tion between adversarial neighbors, offering insight into the role that mutually beneficial behaviors

127 These studies provide new insight into the sequence requirements for developing no

128 understanding of protein functions requires insight into the structural and reaction dynamics.

129 These data provide insight into the vaccine design and evaluation of immuno

130 tissue microenvironment can provide valuable insight into their function.

131 interactions for the double mutant, provides insight into their roles and a quantitative measure of t

132 control subjects can potentially provide new insight into these issues.

133 DFT calculations provide insight into this enhancement deriving it from the favor

134 verall, this paper not only provides a novel insight into time-series ACRHP data mining based on time

135 ensity functional theory calculations, first insights into a long-lived excitonic state are gained an

136 Taken together, our observations provide new insights into A3 enzyme target site selection and how A3

137 These new insights into adipocyte-driven IR may assist development

138 ur studies provide structural and functional insights into an essential protein that is required for

139 These data provide novel insights into beta-PE biosynthesis and advance our under

140 ground-state molecules, the results provide insights into both the electronic and nuclear dynamics o

141 athobiology of this disease and provided new insights into brain angiogenesis by showing uncoupling o

142 Global insights into cellular organization and genome function

143 It can provide clonal-level insights into cellular proliferation, development, diffe

144 a lipid membrane environment provide unique insights into channel activation and inactivation mechan

145 This model provides new insights into charge-ordering phenomena in transition-me

146 This observation offers insights into charge-symmetry-breaking forces acting in

147 sibly) auxiliary information, and we provide insights into choosing an appropriate target association

148 hting the ability of our approach to deliver insights into chromatin organization of great biological

149 MD) simulations seek to provide atomic-level insights into conformationally dynamic biological system

150 sis of these data, enable new, systems-level insights into disease pathogenesis.

151 ion of the lysimeter study with CSIA enabled insights into DPC transformation in the field that are s

152 on profiling provides additional mechanistic insights into full-length kinase functions by reporting

153 rity, and invasiveness, but it also provides insights into fundamental processes such as dispersal an

154 making it a powerful tool for gaining novel insights into genome evolution.

155 comparative genomic analysis provides unique insights into glioma etiology and the chronology of glio

156 iochemical data, we attempt to summarize new insights into hERG-specific function and articulate impo

157 ctrophysiology and ISH, provides mechanistic insights into how both chronic alcohol exposure and prot

158 These findings provide mechanistic insights into how CHRNA3 risk alleles can increase the r

159 Taken together, our results provide insights into how FOXA1 mutations perturb its function t

160 These findings provide insights into how GLI1 controls gene expression in cance

161 ed complex formation and provide mechanistic insights into how SARAH domain-mediated interactions inf

162 Exciting recent data have provided novel insights into how these ABO effects are modulated and ha

163 In this Review, we discuss recent insights into how these important cellular events are pe

164 We also provide mechanistic insights into how these novel cyclotides interact with a

165 and genome-wide RALY-binding pattern reveal insights into its cooperative interactions and mode of a

166 he 2NS translocation that provided excellent insights into its frequency over years and indicated its

167 this molecule, which will provide important insights into its function as well.

168 ein family, and provide detailed mechanistic insights into its inhibitory function.

169 ve disease-modelling strategy may reveal new insights into mechanisms of cardiac disease and serve as

170 her complementary techniques, we provide new insights into mitochondrial structure and function in al

171 Our results provide detailed insights into Na(v)1.5 structure, pharmacology, activati

172 perando conditions that will enable profound insights into nanoscale catalytic mechanisms.

173 ll as associated pathways in nACD, providing insights into pathophysiology with the potential to unra

174 The methodology promises new insights into phosphorus as well as other structurally c

175 tion of these mechanical forces will provide insights into physiology and pathophysiology that more c

176 cies adapted to varying rainfall can provide insights into plant habitat distribution and drought ada

177 ssue of Blood, Noubouossie et al provide new insights into potential mechanisms for thromboinflammato

178 Discoveries in this field provided insights into primary immunodeficiencies, inherited auto

179 Insights into pyrin regulation have come from studies of

180 This work affords new insights into realizing a stable Li metal anode for high

181 The findings provide novel mechanistic insights into receptor-operated TRPC4 activation by coin

182 These findings provide novel insights into reduced flexible behavior in relation to c

183 Structural insights into setron-binding poses and their inhibitory

184 n of techniques allows us to obtain valuable insights into structural, electronic, and dynamic inform

185 Fundamental insights into structure-property relationships of 6FDA-b

186 roteostatic pathway of mHTT, providing novel insights into such pathological activities.

187 , infants, and children can provide valuable insights into the adaptation of T cell subsets.

188 Our results provide new insights into the basic biology of adjuvant-elicited cel

189 These insights into the biological responses of tumors to ICI

190 ry epithelial cell cultures that can provide insights into the biology of the intestinal epithelium a

191 crystal structures of AaTPS and FgGS provide insights into the catalytic mechanism of this cryptic fu

192 of lysosomal organelles for egress provides insights into the cellular and immunological abnormaliti

193 ghlight the potential of SSCE-MRI to provide insights into the cerebral microvasculature post-TBI.

194 Insights into the characteristics and behaviors related

195 nterrogate SV contents will facilitate novel insights into the chemical basis of neurotransmission.

196 Molecular modeling studies provided new insights into the chemical features required for optimal

197 To gain insights into the coevolution of this interkingdom preda

198 sponses measured by the antennograms offered insights into the comparative olfactory physiology of th

199 role for TLR2 in DENV infection and provide insights into the complex interaction between the virus

200 ouse genomic regions, are providing valuable insights into the contribution of triplicated genes or g

201 These data give insights into the development and selection of humanized

202 Our findings provide new insights into the development of NKTCL by showing the im

203 ory receptors may play a role, providing new insights into the developmental evolution of complex che

204 Taken together, our data provide new insights into the differentiation of transposons and the

205 vailable datasets might help to gain further insights into the disease process.

206 and theoretical investigations that provide insights into the diverse pathways to access triplet exc

207 Altogether, these findings provide insights into the dual roles of tumor-associated senesce

208 ith widely used approaches and provide novel insights into the dynamics of viral mutation and evoluti

209 Detailed insights into the effect of excitonic coupling dynamics

210 scale GWAS in a Japanese population provides insights into the etiology of complex diseases and highl

211 ization in prokaryotic chromosomes and yield insights into the evolution of eukaryotic chromosome con

212 unstable globins and red cell lysis and also insights into the factors governing hemoglobin assembly

213 nding groups for WT and mutant KSIs provided insights into the forces and interactions that allow and

214 amics simulations provide useful mechanistic insights into the free energy of interaction between the

215 le oncogenic transcription factors, provides insights into the functions of protein ADP-ribosylation,

216 Our study provides novel insights into the fusogenicity of MuV and its influence

217 light on this complex infection and provide insights into the future of microbiota-based therapeutic

218 Our study provides insights into the genomic properties of structural varia

219 ting biomolecules in real time could provide insights into the health status of patients and their re

220 with response to GS-9688 treatment provides insights into the immune mechanisms that mediate this an

221 Si/inner-SEI/outer-SEI), thus offering novel insights into the impact of SEI homogeneities on the str

222 16, and MCF7 human cancer cell lines provide insights into the impact of structural features on poten

223 Our study provides novel insights into the influences of biogeochemical water typ

224 al approaches to build a model that provides insights into the limited activity of HDACi in clinical

225 on-rich substituents at C4, giving important insights into the mechanism of the photolysis reaction.

226 r, these data provide physiological EV-based insights into the mechanisms of human malaria pathology

227 or SAR1B in lipoprotein secretion, providing insights into the mechanisms of large cargo secretion th

228 Therefore, this work not only supplies insights into the mechanisms of methane coupling reactio

229 1 binds CENP-A/H4 and CENP-C, we provide key insights into the minimalistic principles underlying cen

230 nd within the NER bubble, provide structural insights into the molecular basis for malfunction of dis

231 conjugated polymers, thus also providing new insights into the molecular design guidelines for the ne

232 lecular omics data can provide comprehensive insights into the molecular footprints of cells.

233 Our results provide insights into the molecular mechanism of HSF2BP-S167L in

234 s recent work that has revealed exciting new insights into the molecular mechanisms that allow cells

235 This work provides critical insights into the nanoparticle growth process and precur

236 n increasingly important means to gain novel insights into the natural world.

237 Overall, these studies provide novel insights into the nature and function of human B-cell co

238 These outcomes provide insights into the neural mechanisms underlying memory en

239 Drawing on recent insights into the neurocomputational properties of the m

240 Together, our research provides molecular insights into the nucleosome-based recognition and histo

241 Insights into the operating mechanism are presented.

242 Our findings provide insights into the origin and evolution of redox regulati

243 ted negative-sense RNA viruses have provided insights into the overall NC architecture.

244 ty, and the transition metal L-edges to gain insights into the oxidation/reduction processes of posit

245 Finally, further insights into the pathogenesis of EoE have revealed seve

246 ed a systems biology approach to gain deeper insights into the PCSK6 role in normal and diseased vess

247 Our results provide critical insights into the phase separation of cellular membranes

248 ne in aging populations may provide critical insights into the precursors of late-life dementias.

249 bolic modelling has the potential to provide insights into the processes that underpin osmolyte synth

250 tact dynamics as guidance cues may yield new insights into the regulation of innate immunity.

251 clear phosphoinositide signals, and provides insights into the regulation of rice uniformity via a la

252 h applications, where the aim is to generate insights into the relations between a set of covariates

253 nts within the cradle of humanity may reveal insights into the relationship between early hominins an

254 of Blood, Zhen et al provide novel molecular insights into the requirement for Runx1 in a mouse model

255 al properties of lncRNA genes, revealing new insights into the RNA structure-function relationship, d

256 Our results provide new insights into the role of 3D niche biomechanics in regul

257 rward an alternate mechanism, drawing on new insights into the role of the medial temporal lobe in au

258 ut from a complex tissue and provides unique insights into the roles of Piezo in invasive cell behavi

259 Overall, these data provide novel insights into the signalling molecules and mechanisms re

260 hs (Acinonyx jubatus) to demonstrate how new insights into the socio-spatial organization of this spe

261 To gain insights into the structure and assembly of Abeta oligom

262 This finding provides key insights into the thermodynamic mechanism for the nuclea

263 We provide new insights into the tissue-specific functions of VDRs in m

264 d under permissive conditions, mTPP provided insights into the underlying protein stability changes t

265 ructured regions is integral for mechanistic insights into the viral infection cycle, very little is

266 , called BionoiScores, to provide meaningful insights into their interactions with ligand molecules.

267 To consolidate insights into their sensorimotor functions, this review

268 current research into TPCs, including recent insights into their structures, functional roles, mechan

269 Our study provides novel insights into these key intermediates, their relevance f

270 olutionary history of P. xylostella provides insights into transoceanic movements that have enabled i

271 rful neutrophilic oxidants may provide novel insights into treatment options that potentially comprom

272 glycolysis, respectively, which may provide insights into understanding miRNA signaling underlying c

273 This study provides new insights into YAP as a broad transcriptional repressor o

274 iciency can be thermally controlled, and new insight is gained for the spintronic applications of spi

275 is preclinical setting establish fundamental insights, laying the framework for optimization in cell-

276 aptable as an educational tool, and provides insight on the possible coevolutionary origins of aesthe

277 ctional myocardial imaging has offered novel insights on its pathophysiology and prognosis, but its u

278 rprints constitute a valuable tool to obtain insights on the impact of each brewing step on the final

279 s initiated from Rosetta predictions to gain insights on the interplay of amino acid composition, str

280 strong community collaboration, provides new insights on the potential locations of reservoirs of HIV

281 y of host cells to MNV infection can lead to insights on the roles that specific cell types play duri

282 hylation in TAFs and provide new mechanistic insights on the selective poor response of SCC-TAFs to n

283 We review insights on their domestication from new phylogenies, ar

284 To gain mechanistic insights on this unknown, a dynamic root-hydraulic model

285 ork of the healthy cell of origin, a key new insight paving the road to new therapeutic strategies.

286 Together, these new insights provide compelling support for the proposed bud

287 These findings provide novel insight regarding (2R,6R)-HNK's acute mechanism of actio

288 fficient to carry us to a place of truly new insight regarding consciousness.

289 an and animal studies is beginning to expand insights regarding neurobiological systems associated wi

290 Our study provides novel insights regarding the contribution of genetics, in comb

291 SB infants of mothers participating in the INSIGHT study were enrolled into the observation-only an

292 tart Infant Growing on Healthy Trajectories (INSIGHT) study's responsive parenting (RP) intervention,

293 However, new insights suggest that non-haemodynamic tubulo-toxic fact

294 y of expression data provide new mechanistic insights that are consistent with a compensatory/scarrin

295 ce trigger cross-beta fibril formation, with insights that have direct implications for deducing the

296 This model generates mechanistic insights that help in further experiments and modeling.

297 health research communities with predictive insights that may help study and battle this novel 2019-

298 What has emerged are insights they may serve as a framework for understanding

299 l fill a gap in our understanding, providing insights through quantitative exploration of fatty acid

300 On the basis of these insights, we created trametiglue, which limits adaptive