ライフサイエンスコーパス: install

1 those that are synthetically challenging to install.

2 line interfaces only and can be difficult to install.

3 Primary and secondary alkyl groups can be installed.

4 It can be launched on any system that has R installed.

5 ent functional groups were postsynthetically installed.

6 metal corrugated culvert pipes are sometimes installed.

7 c), different patterns of O-sulfation can be installed.

8 c substitution (S(N)Ar) is routinely used to install (19)F(-) and (18)F(-) in aromatic molecules, but

9 f N-H bonds by [Ni(IMes)(2)] is essential to install a Bpin moiety at the N-position as a traceless d

10 d for their synthesis, methods that directly install a free amine group into C(sp(3))-H bonds remain

11 ul drugs and to provide synthetic methods to install a gem-dimethyl group.

12 of carcinogenic chloromethyl methyl ether to install a protecting group late in the synthesis, and an

13 s disease (requiring a deletion in HEXA); to install a protective transversion in PRNP; and to insert

14 Imine bond formation is employed to install a pyridyl to the alkene trans-cinnamaldehyde whi

15 Asymmetric catalysis is used to install a transient chiral auxiliary starting from achir

16 We have installed a custom-fabricated PET insert into our small-

17 METHODS AND Participants aged >/=18 years installed a mobile application programmed to geofence al

18 We installed a photolabile structural cage on the hydroxy g

19 Five hospitals in three European countries installed a remote wireless vital signs monitoring syste

20 Here, we show that installing a canonical Met ligand in lieu of the Tyr fou

21 Compared to the previous approach of installing a complex U-shaped template to achieve a mole

22 Conversely, installing a kinetic barrier that blocks sliding allows

23 nitrosopyridine leads to a stable conjugate, installing a label at N6-methyl-adenosine.

24 We functionalized the scaffold by installing a metal-binding site consisting of four gluta

25 timized for intravital two-photon imaging by installing a red fluorophore.

26 ite-selective fluorination of peptides, thus installing a specific probe to study peptide-protein int

27 The polymer ligands were synthesized by installing a stoichiometric mixture of amine-modified su

28 Here we show that, by installing a sufficiently reactive handle (e.g., a C-Br

29 a nonheme diiron monooxygenase, PtmU3, that installs a C-5 beta-hydroxyl group in the unified biosyn

30 al S-adenosyl-l-methionine (SAM) enzyme that installs a catalytically essential glycyl radical on pyr

31 We demonstrate that IpoC installs a cysteine-derived thiazoline, whereas PurCD al

32 etabolite and a solid-phase azide resin that installs a diagnostic moiety for MS/MS-based identificat

33 Base editing installs a precise nucleotide change in specific gene lo

34 dentified METTL1 as a methyltransferase that installs a subset of m(7)G within mRNA and showed that i

35 After installing acidic auxiliary groups, the complexes become

36 tude and is a function of both coal rank and installed air pollution control devices.

37 ons with estimates of TE partitioning within installed air pollution control processes.

38 Results show the installed Al-C(aryl) bonds are more prone to decompositi

39 minocarbonylation is a standard approach for installing amide functionality in chemical synthesis.

40 ng programs, Vina requires users to download/install an executable file and to run that file from a c

41 ase domains but confirm its indirect role in installing an alkali-labile moiety as the imprint.

42 ansformation offers an effective approach to installing an amide and an azide from two diffenent amin

43 2% of the maintenance energy budget and that installing an energy-efficient alternative pathway could

44 one such RiPP gene cluster and find that it installs an aliphatic ether cross-link at an unactivated

45 of one of these RaS enzymes and find that it installs an intramolecular beta-thioether bond onto its

46 ee, browser-based, one click, cross-platform install and better navigation interfaces.

47 on off-the-shelf parts, provides an easy to install and maintain platform, offering an out-of-box ex

48 commonly used, making it straightforward to install and maintain.

49 ADDO is customizable and convenient to install and provides extensive analytics and visualizati

50 a diverse collection of enzyme catalysts to install and remove halogens from organic scaffolds has e

51 We introduce a general strategy to install and remove surface groups by performing substitu

52 HUNER comes in containers, making it easy to install and use, and it can be applied off-the-shelf to

53 er the MIT license, enabling institutions to install and users to expand and modify the application f

54 gists who may not have programming skills to install and utilize Simbiotics, we present in this appli

55 developed a sulfonate tag that can easily be installed and enables highly efficient solid phase extra

56 mained at baseline levels while inflammation installed and endured.

57 (6)-methyladenosine (m(6)A) RNA modification installed and erased by N(6)-methyltransferases and deme

58 nd rkt frameworks, that allow software to be installed and executed under an isolated and controlled

59 onstrate that glyoxal modification is easily installed and potently disrupts nucleic acid structure a

60 All prostheses were successfully installed and stabilized intraoperatively.

61 The XyCAM RI was installed and used in two different settings to obtain v

62 The device was successfully installed and used to develop clinical DS.

63 an inexpensive, scalable, and easy means of installing and expressing genes directly from the yeast

64 The application installs and runs on all major platforms and does not re

65 Polycomb repressive complex 2 (PRC2) installs and spreads repressive histone methylation mark

66 nstallability test, 51% were deemed "easy to install," and 28% of the tools failed to be installed at

67 o biological information without the need of installing any local database.

68 o stealthin C reveals a distinct approach to install aromatic amino groups in metabolites and raises

69 op a methyltransferase (writer) variant that installs aryllysine moiety on histones that can only be

70 encode unusual metalloenzymes, as these may install as yet unknown alterations.

71 which could be sustained by the B currently installed as CFI for >10 years.

72 ost GNSS is an accurate monitoring tool when installed as custom-made, short-baseline networks.

73 ABEMUS is cross-platform and can be installed as R package.

74 Furthermore, the auxiliaries were installed as S- and R-stereoisomers.

75 of the biggest AWL-reactor to date that was installed at a coal-fired power plant in Germany.

76 install," and 28% of the tools failed to be installed at all because of problems in the implementati

77 ld be significantly reduced when solar PV is installed at high elevations.

78 g a single diverging terpyridine (tpy) group installed at its upper rim.

79 ble expression cassettes, i.e. landing pads, installed at known safe-harbor sites in the yeast genome

80 stem occupies a small volume, can be readily installed at other light sources.

81 d independently on two Discovery MI scanners installed at Stanford University and Uppsala University,

82 e precursors, allowing the heteroatoms to be installed at the 1-position or 1- and 12-positions of th

83 ed a set of heterocyclic phosphines that are installed at the 4-position of pyridines as phosphonium

84 When installed at the beta-position, aminomethyl substituents

85 A diverse range of amides are successfully installed at the branched position of terminal alkenes i

86 nctional groups to be tested were separately installed at the interface of two interacting proteins i

87 n even wider variety of functionality can be installed at the quaternary carbon by using 1,2-disubsti

88 ion PET/CT system (Siemens Healthineers) was installed at the University Medical Center Groningen.

89 2018, the Biograph Vision PET/CT system was installed at the University Medical Center Groningen.

90 We designed a three-step approach for installing authentic posttranslational modifications in

91 ss to firearms, poisons, and medications and installing barriers to prevent jumping from lethal heigh

92 This cell was installed between the ion mobility and time-of-flight re

93 , UV/vis detector, and a Rheodyne valve were installed between the zone eluting interface (after norm

94 ontainers allows labs of all sizes to easily install bioinformatics software, maintain multiple versi

95 TCR gene transfer installed BOB1 specificity and reactivity onto recipient

96 nd arylation, deprotection, and amidation to install broad molecular diversity in short order.

97 The installed Bu(3)Sn groups serve as chemical handles for f

98 The indenylidene ligand can be reliably installed, but to date yields much less reactive catalys

99 the most prominent mRNA modification, and is installed by a large methyltransferase complex (the m(6)

100 is reaction marks the first ether cross-link installed by a RaS enzyme.

101 hydrobutyrine, which are posttranslationally installed by class I lanthipeptide dehydratases (LanBs)

102 ible post-translational modification that is installed by the DHHC family of palmitoyltransferases an

103 s the most abundant mRNA modification and is installed by the METTL3-METTL14-WTAP methyltransferase c

104 N(6)-methyladenosine (m(6)A), installed by the Mettl3/Mettl14 methyltransferase comple

105 cular lysine-tryptophan cross-link, which is installed by the radical S-adenosylmethionine (SAM) enzy

106 ccurs in the context of CpG dinucleotide, is installed by two denovo DNA methyltransferases, DNMT3A a

107 RTXI is easy to install, can be used with an extensive range of external

108 Under the scenario of quadrupled installed capacity there is a small decrease in system-w

109 scales does not increase with increasing WT installed capacity.

110 rganic framework (COF), COF-616, bearing pre-installed carboxyl groups.

111 t a number of methods have been reported for installing CH(2) F and CHF(2) groups, they are mainly li

112 y high surface area materials with precisely installed chemical features, which provide new opportuni

113 chain-propagation process and is capable of installing chlorine atoms at primary, secondary, and ter

114 lerometers that collected activity data, and installed climate loggers in each individual's home rang

115 ure (high deposition velocity), which can be installed curbside, proximal to the emitting vehicular s

116 nd substantial effort reading documentation, installing dependencies and moving between analysis and

117 fer protocol can efficiently and selectively install deuterium (D) and tritium (T) at alpha-amino sp(

118 bonds and aliphatic alkynes using an in situ-installed directing group.

119 We use RDN to install disease-associated point mutations in HEK293T ce

120 current Cas9 nuclease-based method, and can install disease-correcting or disease-suppressing mutati

121 A novel DNA strand-specific 'imprint', installed during DNA replication at the mating-type locu

122 d TF chromatin access, respectively, thereby installing ectopic erythroid potential.

123 This change was achieved by installing EEC meters in each apartment.

124 It can be used to install ethyleneamine groups by exploiting its terminal

125 which can be used to bias sex determination, install exogenous information, or remove endogenous DNA

126 rein, this problem is resolved by chemically installing extended pai-rich alternating carbon-carbon l

127 n of electron-donating ligands to active MOF-installed Fe-porphyrins dramatically alters their electr

128 8 +/- 1.2 dB in a link comprised of 90 km of installed fiber with additional optical attenuation intr

129 s of birefringence introduced by 18.23 km of installed fiber.

130 ce against polarisation fluctuations over an installed fibre network.

131 ive for cancer researchers and can be easily installed for either personal use or deployed on servers

132 e followed by a molecular rearrangement that installs four new bonds.

133 qDiff function in R package Tnseq and can be installed from the Comprehensive R Archive Network, CRAN

134 ling framework (version 1.4.0), which can be installed from the Python Package Index (PyPI) using a P

135 r is cross-platform, BSD-licensed and can be installed from the Python package index or the bioconda

136 ondary, and tertiary radicals can be used to install functional groups in a convergent manner, which

137 Chemical transformations that install heteroatoms into C-H bonds are of significant in

138 activation, as well as the stability of the installed histone modification.

139 One plastic product and a carpet were installed horizontally to investigate the direct transfe

140 , owes its stability to post-translationally installed hydroxyl groups at position 4 of prolyl residu

141 om simulations = 45-48%, while net CF for WT installed in 2016 = 42.5%).

142 Four diverse aryl groups are installed in a chemo-selective fashion providing a gener

143 nt conditions, specifically the sensors were installed in a historical iron bridge.

144 an SID device was designed and successfully installed in a hybrid FT-ICR instrument in place of the

145 assured by a gasket, and all components are installed in a polylactic acid holder.

146 A vinyl ether moiety was installed in a range of molecules, including amino acids

147 allows quaternary and tertiary centers to be installed in a singular, chemoselective olefin difunctio

148 Global Positioning System (GPS) stations installed in and around the epicenter of the Lushan eart

149 animal MRI systems, the insert can easily be installed in any appropriate MRI scanner or used as a st

150 n membrane and a pH-ISFET, and can be easily installed in barrels.

151 The FF-XRC is very compact and can be installed in different experimental setups.

152 Progressively, the first X-ray machines were installed in hospitals during this period, and the first

153 date, no organic qubit candidates have been installed in MOFs despite their structural variability a

154 RNA extraction and RT-qPCR platform has been installed in NHS diagnostic labs, increasing testing cap

155 When Dha is chemically installed in proteins, the addition of a wide-range N-nu

156 d SVOCs (eight phthalates and adipates) were installed in residential indoor environments.

157 rived from samples, and the Color Picker APP installed in smartphone continued to read out the Red, G

158 work of four active site residues, which was installed in the late stages of laboratory evolution, ap

159 ening of the sulfamate ring once it has been installed in the polymer.

160 The SID device was designed to be installed in the Q Exactive series of Orbitrap mass spec

161 D and E ring of the natural product could be installed in three additional steps.

162 in stored rainwater in 36 polyethylene tanks installed in two rural communities of the semiarid of Ba

163 onversions after all of the carbon atoms are installed (including a Sandmeyer halogenation), use of c

164 The QKD system was installed into a 45 km link of a metropolitan telecom ne

165 s where an intact N-N bond is conservatively installed into a pyrazole precursor fragment.

166 A pilot-scale plasma reactor installed into an 8 x 20 ft(2) mobile trailer was used t

167 g CN(-) -responsive linker were sequentially installed into the lattice of PCN-700.

168 Inspired by earlier work, we installed into tobacco chloroplasts synthetic glycolate

169 ssibility of a direct role of Mcm10/Cdc23 in installing it in cooperation with Polalpha and Swi1.

170 herein some conceptual design strategies for installing light sensitivities into the immune signaling

171 source and can be run from our web server or installed locally.

172 thesis of a protein with a site-specifically installed lysine acylation.

173 biological roles of m(6)A, the inability to install m(6)A site specifically in individual transcript

174 CTD phosphorylation code wherein previously installed modifications direct the identity and abundanc

175 of the pore structure, which is achieved by installing modulator groups on the framework linkers, im

176 over time emphasizing the reliability of the installed monitoring system.

177 idly selects for reverse transcriptases that install mutations at sites of a given type of RNA modifi

178 we greatly reduce off-target base editing by installing mutations into our third-generation base edit

179 TRMT10A installs N (1)-methylguanosine (m(1)G) in tRNA, and FTO

180 Finally, we show that ABE8e can efficiently install natural mutations that upregulate fetal hemoglob

181 Methods for installing natural and unnatural amino acids and their m

182 xposed inhabitants lowered their exposure by installing new wells to tap intermediate (45-90 m) aquif

183 tinct synthetic pathways are rationalized to install nitride ligands into targeted positions of W-Fe-

184 of natural glycans and, more importantly, to install non-natural monosaccharides into glycoconjugates

185 ering could enhance therapeutic efficacy and install novel cellular functions.

186 We aimed to evaluate the effect of installing novel passive chlorination devices at shared

187 The sensitivity is readily enhanced by installing numerous matrices that facilitate higher sens

188 on of tyrosyl protein sulfotransferase 1, we installed O-sulfated tyrosine in CDR H3 of both bNAbs.

189 Using specific inhibitors of the enzyme that installs O-GlcNAc (O-GlcNAc transferase, or OGT) and the

190 with fluidics and microdetection that can be installed on a commercial NMR spectrometer.

191 lized in the aperture of a full-sized window installed on a mockup room.

192 internet, an optimized computational kernel installed on a remote computer cluster.

193 y a RGB (red, green and blue) analytical app installed on a smartphone.

194 h-precision diet estimates from nest cameras installed on a subset of nests in lieu of a controlled f

195 yl cysteine amino acid was site-specifically installed on apoptosis protein biomarkers and was furthe

196 Notably, Bdan and Bpin are installed on the alpha- and beta-carbon atoms, respectiv

197 use the self-developed RGB analysis software installed on the cell-phone to obtain the SBA concentrat

198 The cranial window can be simply installed on the mouse skull according to previously est

199 The triazene group precisely installed on the synthesized aryl and pyridyl ring is a

200 required software and databases are locally installed on the system, significantly reducing the depe

201 ctionality including azides and alkynes were installed on tri-N-acetylglucosamine (NAG)3, a PG mimic,

202 tructurally, but the enzymes responsible for installing one m6A residue on each subunit of human ribo

203 The sliding clamp needs to be opened and installed onto DNA by a clamp loader ATPase of the AAA+

204 sferases that can elaborate a glucose primer installed onto protein targets by an N-glycosyltransfera

205 zation of many protecting groups that can be installed or deprotected without affecting other functio

206 to utilize the phenol moiety as a handle to install phosphinites as a recyclable directing group.

207 re readily, two approaches were developed to install phosphorus bonds directly: 1) the synthesis of m

208 ontaining H2B-Ub bearing a site-specifically installed photocrosslinker, here we report an interactio

209 delivery of sgRNA-encoding vectors, we could install point mutations with high efficiency in one or m

210 tically impaired CRISPR protein to precisely install point mutations.

211 al. describes a gene editing tool capable of installing point mutations in mtDNA, and it does not inv

212 We installed polyvinyl chloride plastic bars which have bee

213 sights into how radical SAM (AdoMet) enzymes install posttranslational modifications in RiPPs.

214 c thioether bridge (sactionine bond) that is installed posttranslationally and is absolutely required

215 Alternatively, the C-C bond can be installed prior to the C-N bond via initial C-radical ad

216 he room and the surfaces of the horizontally installed products.

217 Bacteria have the natural ability to install protective postsynthetic modifications onto its

218 protein function and reactivity are used to install radical precursors for homolytic on-protein radi

219 ed hydrazine and dihydrazides can be used to install reactive hydrazide handles onto the side chain o

220 Recent strategies for installing reactive carbonyl groups and alpha-nucleophil

221 (m(6)A), and identification of proteins that install, recognize, and remove this and other marks have

222 The use of an easily installed/removed Si-based auxiliary enables selective I

223 commended to have the financial resources to install sanitary collection and distribution infrastruct

224 We distinguish impacts from newly installed sanitation systems (to achieve universal cover

225 d nutrient and electricity use through newly installed sanitation systems.

226 iversal coverage (referred to here as "newly-installed sanitation").

227 acetylation and lysine succinylation can be installed selectively in ubiquitin and synthesized histo

228 aration software; and/or require the user to install separate programs or plugins.

229 Installing simple plate handling automation allowed us t

230 s-permeable walls, but in the absence of any installed source of gas.

231 One key strategy is to install stations that record signals from Global Navigat

232 Although base editors are widely used to install targeted point mutations, the factors that deter

233 s borono-Mannich reaction of crotylboronates installs tertiary methyl-bearing stereocenters in good y

234 ollowed by a MgI(2)-induced fragmentation to install the 2-oxabicyclo[3.3.1]nonane core of the natura

235 lin ring, and carbonylative lactonization to install the alpha-alkylidene-beta-hydroxy-gamma-butyrola

236 as demonstrated using a SNAP-tag approach to install the boronic acid reagent onto the extracellular

237 A scalable procedure was developed to install the C-3 amido group.

238 rm the C9-C10 bond, and Evans methylation to install the C-8 center.

239 nthesis followed by an O-N acyl migration to install the C-terminal amino alcohol, a different strate

240 mandelic acid, involving the RCM reaction to install the C18-C19 ring junction, was successful in ass

241 is strategy relies on two aldol reactions to install the chiral centers at C3/C4 and C3'/C4', a lithi

242 serves as a preactivated coupling partner to install the ester side chain.

243 r Diels-Alder furan (IMDAF) cycloaddition to install the indole.

244 aerial oxygen played a role of an oxidant to install the keto-oxygen functionality.

245 s known biochemical function, Polalpha might install the mat1 imprint during lagging strand synthesis

246 catalyzed methylation method was employed to install the methyl group on the benzene ring.

247 ces H(2)O(2) at its nonheme-iron cofactor to install the oxirane "warhead" of the antibiotic fosfomyc

248 To install the package type: devtools::install_github("Dohe

249 To install the phosphocholine unit, a highly effective phos

250 byproduct, ethyl 2-picolinate can be used to install the picolinamide DG in a direct or indirect mann

251 n confined in the finite nuclear space could install the picture of a particularly dense organelle su

252 dium-catalyzed decarboxylative allylation to install the quaternary bridgehead center.

253 mploying either a late stage ring closure to install the required 3,6-anhydro-bridge or a suitable 3,

254 de precursor undergoes a cascade reaction to install the requisite tetracyclic ring system.

255 on followed by Rh-catalysed fragmentation to install the seven-membered ring and vicinal quaternary s

256 reaction partners, as well as the ability to install the stereocentres remotely from pre-existing fun

257 scaffold and gold-promoted glycosylations to install the synthetically challenging alpha- and beta-gl

258 ot require a separate anion exchange step to install the trifluoroacetate group.

259 peptide synthetase Sln9 in constructing and installing the distinctive acylglycine "basket handle" o

260 hod, a near-IR push-pull sensor was prepared installing the electron-donating and -withdrawing groups

261 it is now possible to build such systems by installing the necessary genetic parts directly into an

262 sis time increases further when building and installing the run programs required for these analyses.

263 ly accessible starting materials and rapidly installs the C1/C4/C5 polar functional groups.

264 nd 2-(oxo)glutarate-dependent oxygenase that installs the endoperoxide of verruculogen by adding O(2)

265 Once the Dha is installed, the introduction of the desired functionality

266 odifications and the enzymes responsible for installing them is constantly expanding.

267 core pathways from different organisms that install these complex and highly variable structures.

268 substrate specificities of the enzymes that install these modifications can provide powerful tools t

269 Too often, however, the difficulty of installing these fragments surpasses the challenges pose

270 However, installing this group using the standard protocol, which

271 as led to numerous innovative strategies for installing this unique functional group.

272 It is even possible to install three contiguous all-carbon quaternary centers u

273 We installed three of these 4 m deep HR-MLWs in the riparia

274 y, and the challenging trans-diol moiety was installed through a selective nucleophilic addition to a

275 d dextran, and hydrophobic acetal groups are installed through direct covalent modification of the de

276 ed during therapy resistance and could be re-installed through the direct use of epigenetic therapies

277 from sanitation systems that will need to be installed to achieve universal coverage (referred to her

278 Point-of-entry filters were installed to capture sporadic release of particulate lea

279 riendly system presented here can be readily installed to reliably and accurately measure physiologic

280 g cytosine and adenine base editors can only install transition mutations.

281 estimate air emission damages from currently installed treatment processes at U.S. drinking water fac

282 an ethyl cuprate and an unusual strategy to install two additional ethyl groups that makes use of a

283 The Johns Hopkins Hospital (JHH) installed two pass-through autoclaves in its biocontainm

284 By installing two different photolabile protecting groups,

285 distributions by using a network of properly-installed ultrasonic transducers that can be controlled

286 g tools, new biosynthetic enzymes capable of installing unusual structural features are continuously

287 ithout any a priori knowledge or the need to install, update, and maintain software or databases.

288 ocumentation and examples, and can be easily installed using conda.

289 Their pyridine ring was efficiently installed using the Ciufolini method.

290 Logomaker can be installed using the pip package manager and is compatibl

291 We installed various functionalities onto proteins and atta

292 Two plastic products were installed vertically to investigate substance transfer d

293 ategy wherein trans-dialkyl substituents are installed very early and carried through to completion,

294 It can be easily installed via Bioconda (Gruning et al., 2018).

295 boxybetaine, and oligo(ethylene glycol) were installed via postpolymerization thiol-ene reactions.

296 ng annular nozzles for aerosol injection and installing windows above and below the culture, the cell

297 The three stereocenters were installed with an AD-mix-beta dihydroxylation step follo

298 constructed with printed circuit boards and installed within a single superconducting magnet and vac

299 ries of ITOs in which functional groups were installed within the cation and anion components of the

300 ll number of cleavable bonds are selectively installed within the strands of thermosets using a comon