ライフサイエンスコーパス: instillation

1 monary inflammation (LPS, cytokine, and acid instillation).

2 Anesthetized rats received one gastric fluid instillation.

3 med again approximately 16 h after endotoxin instillation.

4 alveolar lavage following lipopolysaccharide instillation.

5 n, and transport peaked at about 36 hr after instillation.

6 luid at baseline and 24 hours after allergen instillation.

7 animals for as long as 66 days after initial instillation.

8 ound in the lumbar lymph nodes at 36 hr post-instillation.

9 ge fluid at baseline and 24 h after allergen instillation.

10 s directly accessible by aerosol delivery or instillation.

11 % corneal swelling within 5 hours of topical instillation.

12 ion were quantified in rat models after lung instillation.

13 y than control PA01 2 hours of intratracheal instillation.

14 red with BLT1(+/+) BMDCs after intratracheal instillation.

15 d 30 seconds, 2 minutes, and 5 minutes after instillation.

16 Medical, Inc., Salt Lake City, UT) with each instillation.

17 r lubricant instillation and 20 minutes post-instillation.

18 mpathetic access was increased after timolol instillation.

19 cts with emmetropia before and after timolol instillation.

20 s in paratracheal LN after eosinophil airway instillation.

21 ere retained in the lung after intratracheal instillation.

22 detected in the lung 5 h after intratracheal instillation.

23 into the airways of mice after intratracheal instillation.

24 nificant improvement after phenylephrine 10% instillation.

25 cations of acute toxicity up to 7 days after instillation.

26 lmonary damage evoked by intravenous histone instillation.

27 kine release into the airways upon local LPS instillation.

28 iBALT formation, even long after particulate instillation.

29 rapeutically to rats after LPS intratracheal instillation.

30 rmal eyes up to 30 min after fluorescein dye instillation.

31 on subject reports of discomfort after drop instillation.

32 ial structures that contain plant-processing instillations.

33 ctant, but not air, for up to 24 hours after instillation (0.36 [0.11] vs 0.43 [0.18]; P < .005).

34 Unilateral pleural effusion instillation (13 mL/kg), intra-abdominal hypertension (1

35 Bacillus Calmette-Guerin instillation after removal of the tumor is the first lin

36 Artificial tear instillation alone or CC combined with ATs or EH signifi

37 HA instillation also improved the level of HA receptors (CD

38 However, HA instillation ameliorated bladder hyperactivity, lessened

39 s also conducted immediately after lubricant instillation and 20 minutes post-instillation.

40 on of a cisternal catheter allowed bacterial instillation and cerebrospinal fluid (CSF) sampling.

41 f interest placed over the area of endotoxin instillation and in an equivalent lung region on the lef

42 fter lower, but not upper, respiratory tract instillation and that this transfer of virus appears not

43 pulmonary fibrosis, intratracheal bleomycin instillation and thoracic irradiation, we find increased

44 re killed 2 weeks or 3 weeks after bleomycin instillation, and lung tissue, bronchoalveolar lavage (B

45 sport was evident at 4 hr after intravaginal instillation, and transport peaked at about 36 hr after

46 atory distress syndrome by hydrochloric acid instillation, animals underwent a decremental positive e

47 e Wistar rats to repeated lipopolysaccharide instillations, associated or not with a chronic hypoxia

48 rial infection after a single intra-tracheal instillation at a very low dosage of 0.1 mg/kg.

49 IOP was evaluated before and after morning instillation at months 2, 3, 5 and 6.

50 Docetaxel was administered as six weekly instillations at a starting dose of 5 mg, with a dose-es

51 Three days after instillation, bronchoalveolar lavage was performed and p

52 had a pars plana vitrectomy and silicone oil instillation combined with phacoemulsification for tract

53 d more neutrophils to the lung 4 hours after instillation (CXCL1: mTBI = 6.3 +/- 1.3 versus TT = 3.3

54 330 mug of Mn (MnCl(2) 30 mg/kg, intranasal instillation, daily) for 3 weeks.

55 th purified vitronectin before intratracheal instillation decreased efferocytosis in vivo.

56 rophylactic) or 24 h after (therapeutic) LPS instillation decreased neutrophil trafficking to the lun

57 nly 2 of 4 monkeys given the vaccine by oral instillation developed detectable neutralizing antibodie

58 emented chow beginning on day 1 of bleomycin instillation (early treatment, study of antiinflammatory

59 erleukin-10 were administered by intrarectal instillation, either once or twice following an ethanol

60 as retained in the alveolar space after lung instillation even after LPS stimulation, whereas the MHC

61 n was established by intratracheal bacterial instillation followed by proper inhalation, while keepin

62 Interestingly, in such mice, topical OVA instillation following engraftment of exogenous CD11b+ D

63 vin in hydroxylpropyl methylcellulose (HPMC) instillation for 10 minutes followed by 10 minutes of ul

64 C57BL/6J mice received IL-4 by intratracheal instillation for 7 days.

65 a useful alternative to rapid intratracheal instillation for the delivery of exogenous surfactant in

66 e room in which other patients underwent BCG instillations for bladder cancer without required biolog

67 ed through intubation-assisted intratracheal instillation (IAIS) into the lung exhibited improved pha

68 ion and oxidative stress caused by caspase-3 instillation in a mouse model of apoptosis-dependent emp

69 el by up to 100-fold following intratracheal instillation in healthy mice.

70 and elimination pathways after intratracheal instillation in mice.

71 risingly short retention after intratracheal instillation in rat lungs, and incorporation of Ba withi

72 entation of lung ceramides via intratracheal instillation in rats significantly decreased the engulfm

73 dependent feed-forward loop, since caspase-3 instillation in the lung markedly increased EMAPII expre

74 stablished a mouse model with intranasal LPS instillation in the presence or absence of BI (15% of bo

75 tion to baseline was increased after timolol instillation in the subjects with myopia only.

76 Pb from indoor dust following a single dose instillation into C57BL/6 mice.

77 Following intratracheal instillation into naive mice, PS50G were preferentially

78 Mice vaccinated via instillation into the bladder developed protective respo

79 SAA instillation into the lungs elicits robust TLR2-, MyD88-

80 wever, urethral catheterization and contrast instillation is still necessary.

81 Intratracheal instillation (IT) of the aqueous extracts induced a 24 h

82 sher 344 (F344) rats following intratracheal instillation (IT).

83 After intratracheal instillation, labeled apoptotic cells were observed in m

84 tory effect) or on day 8 following bleomycin instillation (late treatment, study of antifibrotic effe

85 This dose and volume of transoral instillation led to a greater penetrance of silicosis in

86 Results: Intratracheal lipopolysaccharide instillation led to an acute inflammatory response in th

87 Pseudomonas aeruginosa tracheal instillation led to an acute pneumonia with a rapid decr

88 alate eye drops administered through topical instillation limits its therapeutic efficacy and poses a

89 However, exposure to acrolein after LPS instillation markedly diminished the LPS-induced product

90 ccus faecalis, we used a mouse transurethral instillation model to address the hypothesis that an inn

91 The direct-instillation nasal allergen challenge (NAC) and the envi

92 An initial recording was made after instillation of 1 muL 0.1% fluorescein followed by furth

93 atients by micropipette, the WO sample after instillation of 10 muL saline.

94 ameter disc of epithelium; immediately after instillation of 2 drops of riboflavin 0.1%-dextran T 500

95 roups in which fecal peritonitis (peritoneal instillation of 2 g/kg autologous feces) was induced, an

96 nic inflammation was induced by intracolonic instillation of 2,4,6-trinitrobenzene sulfonic acid (TNB

97 , i.e., 4 sets of 12 breaths of room air and instillation of 30 mL normal saline.

98 After instillation of 5 muL2% fluorescein, subjects were asked

99 measured in anesthetized, ventilated mice by instillation of 5% bovine serum albumin into the depende

100 Importantly, intratracheal instillation of 8-pCPT-cGMP in BALB/c mice increased ami

101 Instillation of a CFTR inhibitor (CFTR(inh-172)) attenua

102 On intranasal instillation of a fully virulent strain, Yersinia pestis

103 Intratracheal instillation of a lethal dose of ricin (20 microg/100 g

104 urfactant replacement therapy (SRT) involves instillation of a liquid-surfactant mixture directly int

105 nt Replacement Therapy (SRT), which involves instillation of a liquid-surfactant mixture directly int

106 symptomatic management was achieved with the instillation of a sclerosant agent into the pleural spac

107 anti-tumor efficacy following intratracheal instillation of a single dose in a Lewis lung carcinoma

108 The instillation of a single dose of Fab into the lungs of m

109 trophils and demonstrated that intratracheal instillation of a TAT-conjugated PKCdelta inhibitory pep

110 lone and combined with CC in random order or instillation of a volume-matched saline control.

111 ial oxidant activity, responses to pulmonary instillation of A. fumigatus conidia were examined.

112 Co-instillation of AAV9 vector with neuraminidase into mous

113 dary challenge was replaced by intratracheal instillation of allergen-pulsed bone marrow-derived dend

114 Instillation of an emulsion eye drop significantly incre

115 g and lipid layer thickness before and after instillation of an emulsion eye drop.

116 Intraductal instillation of an RCAS vector carrying the polyoma midd

117 Intratracheal instillation of anti-MHC class I Abs, but not isotype co

118 Direct bladder instillation of antibiotics has proved disappointing in

119 se mechanisms, we also found that intranasal instillation of antibiotics or an inhibitor of reactive

120 tory center on the day of surgery before the instillation of any ophthalmic medications.

121 Intratracheal instillation of apoptotic cells enhances resolution of e

122 D-null mice were exposed to an intratracheal instillation of asbestos or bleomycin.

123 inflammatory reaction, such as intravesical instillation of Bacillus Calmette-Guerin.

124 Intravesical instillation of bacterial lipopolysaccharides (LPS) (Esc

125 Airway instillation of bacterial LPS, a known complement activa

126 there was an increase in lung barium post-IT instillation of BaSO(4) NPs while barium from BaCl(2) wa

127 st group of mice were infected by intranasal instillation of bioluminescent strain 536 and received 5

128 lmonary fibrosis induced by an intratracheal instillation of bleomycin (control mice were instilled w

129 nvestigate this issue, we used intratracheal instillation of bleomycin as a model of acute lung injur

130 emale C57BL/6 mice by a single intratracheal instillation of bleomycin.

131 f pulmonary fibrosis after the intratracheal instillation of bleomycin.

132 nt increase in measurement variability after instillation of both low-viscosity and high-viscosity ey

133 Analgesia for breast surgery including instillation of bupivicaine, paravertebral block, and co

134 Rats were colonized by intratracheal instillation of Candida albicans.

135 inistration of live E. coli or intratracheal instillation of carrageenan plus myeloperoxidase via fac

136 The single intratracheal instillation of caspase-3 siRNA not only attenuated lung

137 th transurethral resection and perioperative instillation of chemotherapy for most patients.

138 h transurethral resection with perioperative instillation of chemotherapy recommended for most patien

139 flammasome reporter mice, we showed that the instillation of CLCs into the lungs promoted the assembl

140 We developed a mouse model in which instillation of ClO(-) before ovalbumin (OVA) induces AH

141 urethrogram but detectable during positional instillation of contrast cystography.

142 Acquisition of iso-volumetric data sets with instillation of contrast into the fistula delineates the

143 bits acute exacerbation after intrapulmonary instillation of corisin or after lung infection with cor

144 nse to crocidolite asbestos was addressed by instillation of crocidolite asbestos in a series of wild

145 vaccine Ags was far superior to intravaginal instillation of CXCR3 chemokine receptor ligands or TLR

146 experimental allergic asthma, the intranasal instillation of dust extracts from Amish but not Hutteri

147 yndrome was induced in rats by intratracheal instillation of E. coli (1.5-2 x 10 CFU/kg).

148 lator-associated pneumonia via endobronchial instillation of either Escherichia coli group (n = 11) o

149 tive baseline keratometries were followed by instillation of either high- or low-viscosity eye drops.

150 Intratracheal instillation of either lipid caused substantial neutroph

151 Here we show that instillation of either long CNTs or long asbestos fibers

152 Intra-bronchial instillation of endotoxin into the distal airspaces resu

153 Intratracheal instillation of endotoxin-free HA (25 mug) enhances the

154 Intratracheal instillation of endotoxin-free low molecular weight hyal

155 Intranasal instillation of eotaxin-2/CCL24 before allergen challeng

156 d-type (WT) and mCAT mice with intratracheal instillation of Escherichia coli LPS and found that mCAT

157 in the untreated hosts, were activated upon instillation of exogenous autoantigen.

158 Topical instillation of eye drops remains the most common and ea

159 an 5 minutes should be allowed to pass after instillation of eye drops.

160 In contrast, airway instillation of fluorescent Ag revealed a significantly

161 to the olfactory bulbs following intranasal instillation of H1N1 in Rag knockout mice.

162 uals with allergic asthma and the intranasal instillation of HDM in mice resulted in increased OPN le

163 ronan induces AHR dependent on CD44, whereas instillation of high molecular weight hyaluronan protect

164 cationic protein (ECP)] induced by bronchial instillation of house dust mite (HDM) in patients with a

165 Anesthetized CD-1 mice underwent orotracheal instillation of hydrochloric acid.

166 Intranasal instillation of IFN-gamma-neutralizing antibody partiall

167 arinii-infected mice were treated with local instillation of IL-12 and gene transfer of the IL-12 gen

168 Intranasal instillation of IL-22 with TNF-alpha, but not IL-17A, el

169 Airway instillation of IL-25 induced IL-4 and IL-13 production

170 In addition, intratracheal instillation of IL-36alpha enhanced mRNA expression of i

171 sols, and Study 2: single intratracheal (IT) instillation of increasing doses of BaSO(4) NPs or BaCl(

172 , some of the animals received intratracheal instillation of Klebsiella pneumoniae and were subsequen

173 Intratracheal instillation of L-selectin-deficient (L-Sel(-/-)) mice w

174 Intratracheal instillation of leptin at a dose that was observed in th

175 r tlr4 mice were challenged by intratracheal instillation of lipopolysaccharide (0.3 mg/kg) for 2 hrs

176 Moreover, intratracheal instillation of lipopolysaccharide induced more severe l

177 f luminal monocyte/macrophages by intranasal instillation of liposomal clodronate diminished pneumoco

178 ophage depletion by repetitive intratracheal instillation of liposomal clodronate.

179 One h after intratracheal instillation of liposomal fasudil, mean pulmonary arteri

180 methasone sodium phosphate and preperitoneal instillation of local anesthetic (PILA) with dexamethaso

181 Direct instillation of long and short CNTs into the pleural cav

182 Intratracheal instillation of low concentrations of adenosine (< or =1

183 lung CXCL5 expression depended on RelA after instillation of LPS but not pneumococcus.

184 Ethanol mice given a tracheal instillation of LPS demonstrated early lung fluid cleara

185 isolated from mice showed that intratracheal instillation of LPS induced ROCK activation in lung ECs

186 However, intratracheal instillation of LPS resulted in accelerated recruitment

187 e lung injury (ALI) in mice featuring airway instillation of LPS, ALI was dependent on availability o

188 thmatic, and atopic asthmatic) 4 hours after instillation of LPS, house dust mite antigen, and saline

189 After intratracheal instillation of LPS, ROS generation was impaired in p47(

190 sing Activin-A or treated with intratracheal instillation of LPS.

191 expression of Activin-A or by intratracheal instillation of LPS.

192 In contrast, i.t. instillation of LT-HDM-pulsed DCs induced a similar airw

193 reased on insertion of contact lenses and on instillation of lubricants.

194 Instillation of MHV-CXCL10 into the CNS of CXCL10-defici

195 experimental and modeling data suggest that instillation of microvolumes of liquid into a ventilated

196 After intranasal instillation of MS-WF, mice were infected with Streptoco

197 scales to report discomfort sensations after instillation of NaCl and sucrose hyperosmolar drops (300

198 Intratracheal instillation of neuraminidase (NA) 30 min prior to intra

199 ure were measured, before, and after topical instillation of nicotine in 43 White-Leghorn chickens th

200 nsport was greatly enhanced by prior vaginal instillation of Nonoxynol-9.

201 Instillation of NU14 DeltaampG or NU14 DeltawaaL increas

202 The nasal instillation of only the KLK5-treated virus resulted in

203 In wild-type mice, endonasal instillation of OVA+SEB induced a pulmonary inflammation

204 Using local lung instillation of P. aeruginosa suspended in agar beads we

205 s were isolated 24 hours after intratracheal instillation of PBS or S. pneumoniae, and differentially

206 Transurethral resection and instillation of perioperative chemotherapy remains the t

207 Similarly, intratracheal instillation of PGD(2) enhanced removal of Pseudomonas f

208 Instillation of PGD2 in the nose of sensitized mice toge

209 The intra-tracheal instillation of plasmid encoding for GFP encapsulated in

210 Intratracheal instillation of PLY into C57BL6 mice causes pulmonary al

211 Twenty-four hours after the intratracheal instillation of PM(2.5), wild-type mice showed increased

212 We also show that intrarectal instillation of propionate is sufficient to reproduce th

213 rved that pneumonia induced by intratracheal instillation of Pseudomonas aeruginosa (PA) in mice incr

214 d cotton smoke inhalation injury followed by instillation of Pseudomonas aeruginosa into the lungs.

215 by 48 breaths of cotton smoke and subsequent instillation of Pseudomonas aeruginosa into the lungs.

216 Instillation of ragweed pollen extract, but not of the m

217 Intratracheal instillation of recombinant mouse IL-36alpha induced neu

218 Colonic instillation of recombinant RELMbeta by enema into GC-C(

219 an airway epithelial cultures and intranasal instillation of recombinant sialidase in murine airways

220 %-dextran T 500 20% solution; after repeated instillation of riboflavin 0.1%-dextran T 500 20% soluti

221 e (WT) mice were studied at 6 and 24 h after instillation of S. pneumoniae or PBS.

222 llected foam nasal swabs (NS) obtained after instillation of saline spray were compared with nasal wa

223 Instillation of shuttle peptides combined with SpCas9 or

224 Instillation of silica into the lungs of rodents results

225 Mice received a single intranasal instillation of silica particles and were treated with i

226 as validated in mouse lungs by oropharyngeal instillation of six randomly selected MeONPs.

227 Intravesical instillation of small interfering RNA-containing liposom

228 Vaginal instillation of small-interfering RNA (siRNA) using lipo

229 e bowel syndrome was induced by intracolonic instillation of sodium butyrate.

230 nous and arterial sites before and 4 h after instillation of Streptococcus pneumoniae or Escherichia

231 OP increase (P < 0.001) when assessed before instillation of study treatment.

232 roduction with a maximal effect 7 days after instillation of the adenovirus.

233 enge than WT counterparts because intranasal instillation of the allergen induced markedly reduced le

234 Immediately after the instillation of the lubricant at 4 hours, meniscus varia

235 ritoneal delivery of AAL-R nor intratracheal instillation of the non-phosphorylatable stereoisomer AA

236 Intrabiliary instillation of the transposon-transposase complex was c

237 Nasal instillation of these formulations also evoked antigen-s

238 In vivo analysis indicated that after instillation of thioglycollate to cause aseptic inflamma

239 In the present study, intratracheal instillation of this PKCdelta inhibitor resulted in pept

240 Instillation of thrombin and XeC into adjacent restricte

241 Intracatheter instillation of thrombolytics was more frequent in patie

242 in both eyes while upright (sitting), after instillation of topical anesthetic, with either the Icar

243 swab cultures of the conjunctiva both before instillation of topical antisepsis and 10 minutes after

244 (BrdU) pulse-chase analysis, and intranasal instillation of tracers indicated that instead of contri

245 colitis was induced in mice by intra-colonic instillation of Trinitrobenzene Sulfonate (TNBS).

246 Treatment of mice with intratracheal instillation of TSG6 prevented LPS-induced lung injury a

247 d activity of a non-surgical treatment using instillation of UGN-101, a mitomycin-containing reverse

248 ia the ileostomy and postoperative antegrade instillation of vancomycin flushes via the ileostomy.

249 eased interest in the use of intraperitoneal instillation of various tumoricidals in order to reduce

250 By using a rat model of single orotracheal instillation of whole gastric contents, we studied the t

251 igh mortality, was markedly abrogated by the instillation of wild-type mBMSCs but not of mutant, GJC-

252 Instillation of wild-type PLY but not inactive derivativ

253 Intranasal instillations of exogenous nucleotidase restored the abi

254 us score >40) were registered to receive six instillations of once-weekly UGN-101 (mitomycin 4 mg per

255 Mice were sensitized by means of airway instillations of ovalbumin together with low levels of L

256 ezolid-treated animals were given intranasal instillations of rIFN-gamma before challenge with S. pne

257 Repeated instillations of the two fumes at doses that mimic appro

258 anthracis spore challenge using either nasal instillation or aerosol challenge techniques.

259 ted pulmonary injury evoked by intratracheal instillation or i.p. administration of live E. coli or i

260 ion via liquid suspension through intranasal instillation or intravenous injection.

261 ction have primarily relied on intratracheal instillation or small particle aerosolization of NiV.

262 s of ALI induced by hydrochloric acid, Tween instillation, or in antibody-mediated transfusion-relate

263 We found that upon intratracheal instillation, particulates such as aluminum salts and si

264 PbB was observed between 0.25 and 4 h after instillation, peaking at 8 h and slowly declining during

265 At different times after instillation, PET/CT with (18)F-FDG- or (18)F-4-fluorobe

266 Surprisingly, via intranasal instillation (pneumonic plague model), we saw a differen

267 We also observed that H4R agonist instillation resulted in accumulation of FoxP3(+) T cell

268 A significant increase was found in eye drop instillation self-efficacy from an average score of 2.6

269 rop bottle contamination, increased eye drop instillation self-efficacy, and demonstrated an insignif

270 In C57Bl/6 mice, poly(I:C) instillation significantly increased accumulation of ver

271 SAR 1118 5.0% showed increased instillation site adverse events relative to placebo but

272 w-dose patients, respectively, most commonly instillation site pain (13.9% and 7.1%, respectively).

273 orted ocular AEs were transient intermittent instillation site symptoms (irritation, discomfort) prim

274 nistered by cloud aerosol than by intranasal instillation, suggesting method-dependent differences in

275 outcome was change in participants' eye drop instillation technique as measured by (1) accuracy of an

276 ng session, which included teaching eye drop instillation techniques using a motivational interviewin

277 recent advances of DDS applicable by topical instillation, that have shown better performance in in v

278 eplicated in the monkeys after intratracheal instillation, the first demonstration of replication of

279 Four or 8 h after bacterial instillation, the mice were euthanized, and either bronc

280 Forty minutes after drug instillation, the NITM measurement procedure was repeate

281 When infected by intranasal instillation, these rats rapidly developed fatal pneumon

282 t one week, one month, and three months post-instillation to assess the impact of SPARC on multiple s

283 Hyaluronan (hyaluronic acid; HA) instillation to the bladder has been used to treat KIC.

284 renal pelvis and calyces, maximum 60 mg per instillation) via retrograde catheter to the renal pelvi

285 We recommend that 3 mL be the standard instillation volume for IAP measurement by the intravesi

286 ndings underscore the critical importance of instillation volume on the induction, severity, and type

287 ter epithelial removal and before riboflavin instillation was 373.92 +/- 22.92 mum (range 340-399 mum

288 ministration of E229K thrombin after the C5a instillation was ineffective in reducing alveolitis in W

289 lied for 30 minutes, during which riboflavin instillation was repeated every 3 minutes.

290 Intranasal instillation was used to achieve pulmonary delivery dail

291 the small intestine following intraduodenal instillation,we observed that, in both sexes, the geomet

292 ection who had not received intravesical BCG instillation were selected and the source of infection w

293 longitudinal study, we took advantage of BCG instillations, which increase local immune infiltration,

294 After instillation with drops of Rf solution in distilled wate

295 spergillus fumigatus and challenged via i.t. instillation with live A. fumigatus conidia.

296 ent tumor despite intravesical immunotherapy instillation with the bacillus Calmette-Guerin (BCG) vac

297 inal cord within 1 wk following intracranial instillation with the neurotropic JHM strain of mouse he

298 ndomly assigned for 16 adjuvant intravesical instillations with KLH after preimmunization, and 270 pa

299 ndomly assigned for 11 adjuvant intravesical instillations with MM.

300 -FDG PET/CT scans from day 7 to day 24 after instillation, with a peak of activity measured at day 14