ライフサイエンスコーパス: instruct

1 n poet Horace said poetry gives pleasure and instructs.

2 nd another in which attention was explicitly instructed.

3 een instructed and experienced versus merely instructed.

4 e people, rather than the specific images as instructed.

5 We instructed 73 examinees to malinger red/green blindness

6 ro in our developed device, is sufficient to instruct a functional metabolic zonation during the diff

7 such as ischemia, microenvironmental changes instruct a series of cellular responses that trigger car

8 er, we conclude that NeuroD2 is necessary to instruct a terminal differentiation program in basket ce

9 l blockade of Gsk3alpha/beta and Mek1/2 (2i) instructs a self-renewing ground state whose endogenous

10 These instructed actions were not fixed but rather were learne

11 at different periods while monkeys performed instructed and choice eye movement tasks, to determine t

12 between whether a CS-US contingency had been instructed and experienced versus merely instructed.

13 ng a category-independent neural response to instructed and experienced, but not merely instructed, C

14 while monkeys performed saccade tasks toward instructed and freely chosen targets.

15 ndings point to major roles for microglia in instructing and regulating the proper function of the ne

16 ng revealed a hierarchical organisation with instructing and responding roles: an inner, neural linea

17 lar helper T cells (Tfh) play critical roles instructing, and initiating T-cell dependent antibody re

18 primary auditory cortex (A1) participates in instructing animal behavior remains debated.

19 The function of central appetite neurons is instructing animals to ingest specific nutrient factors

20 pocampus, rapidly forms its memory and later instructs another region, called the neocortex, that sto

21 uitment and activation of immune cells, when instructed appropriately, offer a therapeutic strategy t

22 inuum of noncovalent filaments formed by the instructed assembly (iA) of a supramolecular phosphoglyc

23 Here we show the combination of enzyme-instructed assembly and disassembly to target downregula

24 ide assemblies, with an emphasis on approach-instructed assembly for spatiotemporal control of peptid

25 As the first example of intercellular instructed-assembly from homotypic precursors, this work

26 ortant questions remain about the mechanisms instructing astrocyte cell fate.

27 er activity for memory-guided vs. explicitly instructed attention.

28 lt, some journals, since at least 2013, have instructed authors to provide approximate Snellen equiva

29 October 2016, including 3 of 4 journals that instructed authors to provide Snellen equivalents for vi

30 Ligand receptor interactions instruct axon guidance during development.

31 al development, semaphorin-plexin signalling instructs axon guidance and neuronal morphogenesis.

32 cellular and microenvironmental signals that instruct B cell positioning, differentiation, and metabo

33 y information and how these cellular signals instruct behavioral output is a main goal in neuroscienc

34 cuits producing activity patterns capable of instructing behaviors.

35 phils in early CF pathogenesis, which should instruct biomarker development and antiinflammatory ther

36 the transformation of selfhood, not by being instructed but by people changing in their own ways.

37 rategy task in which two rhesus monkeys were instructed by a visual cue either to repeat or change th

38 plasma cells, and B1 differentiation can be instructed by BCR-mediated self-reactivity, in the absen

39 Cell division orientation is instructed by biochemical and mechanical signals from th

40 ion, inhibition, and intrinsic properties is instructed by distinct cues.

41 eproducible pattern of asymmetric divisions, instructed by divergent canonical Wnt/beta-catenin signa

42 Nervous system development is instructed by genetic programs and refined by distinct m

43 of unfolded protein response (UPR), which is instructed by multiple transcriptional regulatory cascad

44 nal cord can produce a backward pattern when instructed by sensory signals from the limbs.

45 ard alternative interhemispheric circuits as instructed by thalamic input.

46 y to relevant interaural time differences is instructed by the experience of sound localization cues.

47 .3%) did not use the device as frequently as instructed by the manufacturer (>=3 tests per week); 24.

48 In one task, sequential movements were instructed by visual cues, whereas in the other task, mo

49 emergency dispatch centers should offer and instruct bystanders in cardiopulmonary resuscitation dur

50 Antigen (Ag)-presenting cells (APC) instruct CD4+ helper T (Th) cell responses, but it is un

51 ieu present at the time of antigen encounter instructs CD4(+) T cells to differentiate into interfero

52 attributable to a MA delivered AdHu5 vaccine instructing CD8(+) T cell expression of CXCR3(+), CD103(

53 rategies; however, it remains challenging to instruct cell differentiation within a scaffold to produ

54 orylation events that define the context and instruct cell movement.

55 ty (PCP) proteins localize asymmetrically to instruct cell polarity within the tissue plane, with def

56 ng initiated by all three receptors directly instructs cell fate and developmental progression.

57 s chemical, mechanical, or electrical, which instruct cells in which direction to move.

58 gels as proper extracellular matrix that can instruct cellular behaviors are presented.

59 Chromatin remodeling complexes instruct cellular differentiation and lineage specific t

60 uited to an activated enhancer repertoire to instruct changes in chromatin folding, nuclear architect

61 e according to a supervised learning rule to instruct changes in motor output by signaling the occurr

62 must elicit information, calm and reassure, instruct, check procedures, ask for and give opinions,ag

63 After adjusting for potential confounders, instructing CHWs to provide free and convenient distribu

64 firmed, they are going to be a milestone for instructing computational models of brain function.

65 echanical properties of the microenvironment instruct crosstalk between different tissues to control

66 perienced CS-US contingencies than to merely instructed CS-US contingencies.

67 o instructed and experienced, but not merely instructed, CS presentations in the human right amygdala

68 ion through increased expression of the TH17-instructing cytokines IL-1beta, IL-6, and IL-23, whereas

69 indicate that sialic acid-modified antigens instruct DCs in an antigen-specific tolerogenic programm

70 tex (PMd) during the preparatory stage of an instructed-delay center-out reaching task with dense tar

71 cicularis monkeys were trained to perform an instructed-delay reach-to-grasp task in the dark and in

72 Here, we report a new mechanism instructing dendrites to branch versus extend.

73 able to bypass IL-4 upstream signalling and instruct dendritic-cell-specific functional DNA methylat

74 re, we identify a radial signaling axis that instructs developing islet cells to disperse throughout

75 plex signaling network by which RALF ligands instruct different signaling proteins using distinct tar

76 he mouse anterior lateral motor cortex (ALM) instructs directional movements, often seconds before mo

77 Mechanisms instructing disease severity are not completely understo

78 brillator use and high-performance CPR), and instructing dispatch centers on recognition of cardiac a

79 remains unclear how distinct TCR signalling instructs distinct developmental outcomes.

80 ts associated PIWI-interacting RNAs (piRNAs) instruct DNA methylation of transposable elements(3,5).

81 ts associated PIWI-interacting RNAs (piRNAs) instruct DNA methylation of young active transposable el

82 licit and nonmedical (use in ways other than instructed) drug use is common in adolescents and young

83 We show that aggregation method instructs EB lineage bias, with faster aggregation promo

84 substrates for growth and survival, but also instruct effector functions, differentiation, and gene e

85 Subjects were instructed either to not intervene with the imposed pert

86 , Notch regulates its direct target genes by instructing enhancer repositioning.

87 urons, particularly from local interneurons, instructs ensheathing glia to wrap each glomerulus.

88 nate and adaptive antiviral responses and by instructing epithelial cells and dendritic cells of hous

89 r the kidney's urine-concentrating function, instructs epithelial cells to produce chemokines that lo

90 d insulin-like growth factor 1 (IGF1), which instructed expansion and maturation of pulmonary ILC pre

91 se results show that learned versus socially instructed expectations modulate pain via partially diff

92 (24 placebo, 22 tyrosine) was measured in an instructed fear task.

93 Correspondingly, cervical cancer-instructed fibroblasts increased IL23 production in cocu

94 air WNT5A-RYK acts as a navigation system to instruct filopodial pathfinding, a process that is cruci

95 ding training and feedback on new guidelines instructing for explicit targets for arterial oxygen ten

96 igated the role of 3D genome architecture in instructing functional properties of glioblastoma stem c

97 r cortex (ALM) show persistent activity that instructs future actions.

98 n to have selective persistent activity that instructs future actions.

99 In contrast, tissue-specific factors that instruct G proteins during analogous processes in verteb

100 In invertebrates, specific GPCRs instruct G proteins to promote collective apical cell co

101 MJD3 partner to alter the cardiac epigenome, instructing gene expression changes that drive cardiac d

102 The metabolic state of an organism instructs gene expression modalities, leading to changes

103 Transcriptome-instructed genetic analyses revealed that (1) one broadl

104 dings reveal a novel transcription mechanism instructing HSC fate by pausing-mediated differential re

105 The T cell-instructed IL-1beta resulted in systemic inflammation, w

106 AT5 as a central node in the TF network that instructs ILC development, homeostasis, and function and

107 onents interfere with the immune control and instruct immune cells to support, rather than counteract

108 Participants were instructed in advance about the nature of the visual per

109 A proteome-instructed in vivo screen identified 20 cell-surface mol

110 cally by enabling the ad-hoc coding of newly instructed individual rule identities during their first

111 rough the canonical BMP signaling cascade to instruct inflammatory-type LCs and to promote psoriatic

112 BMP7/BMPR signaling in keratinocytes, which instructs inflammatory DCs to gain enhanced Treg-cell-st

113 y reward-seeking, in particular dopamine, to instruct information-seeking.

114 hibiting HDACs to reinforce Notch signaling, instructing ISC self-renewal and lineage decisions.

115 Yet, since infants cannot be instructed, it remains unclear to what extent theta osci

116 promote auditory sensory differentiation and instruct its graded pattern are largely unknown.

117 to the cerebellum encode error signals that instruct learning.

118 store information about rewarded stimuli to instruct long-term changes in excitatory connectivity in

119 emonstrates that a high collagen density can instruct macrophages to acquire an immunosuppressive phe

120 We instructed male rhesus macaque monkeys to initiate sacca

121 Cocultures of cervical cancer-instructed mDCs and cervical fibroblasts led to potent p

122 e Th1-polarizing cytokine IL12 in the cancer-instructed mDCs was strongly reduced.

123 L23 production in cocultured cervical cancer-instructed mDCs, which mediated subsequent Th17 cell exp

124 the IL12 subunit IL12p35 in cervical cancer-instructed mDCs.

125 ue the adhesive capacity of the surfaces and instruct mesenchymal stem cell (MSC) response.

126 ligands, while IFNgamma produced by NK cells instructs microglia toward an inflammatory phenotype, an

127 We find that neuronal IL-33 instructs microglial engulfment of the extracellular mat

128 -resident cardiac macrophages differentially instruct monocyte fate specification.

129 tes in cutaneous psoriatic lesions, and BMP7 instructs monocytic cells to acquire characteristics of

130 PCs) including dendritic cells and monocytes instruct naive T cells to differentiate into various eff

131 Microvascular ECs instruct neighboring cells in their organ-specific vascu

132 radient-independent role of Wnt signaling in instructing neurite pruning.

133 environmental cues in the germinal zone (GZ) instructing neuron polarization and their coupling durin

134 dynamics whereby ingression of pioneer cells instructs neuronal specification.

135 to the integrity of microtubules in order to instruct neuroregeneration.

136 lla, suggesting that medullary signals might instruct NKT2 cells to produce IL-4.

137 S cell- and adult progenitor-derived, GM-CSF-instructed, nonconventional DC subsets.

138 during the trials in which participants were instructed not to encode the presented stimulus.

139 Each participant was instructed not to speak for 2 minutes, simulating a "no-

140 She was instructed not to use a moldy humidifier and not to go t

141 Before the search tasks, a cue instructed observers which item to look for first (curre

142 Our data can instruct on pharmacophore properties to assist the futur

143 as knowing, rather than reckless, even when instructed on the relevant legal criteria.

144 th the management of patients with ELVO were instructed on the use of the following protocol for pati

145 g pathways can detect the order of events to instruct opposing forms of synaptic and behavioral plast

146 articles can serve as carriers or sensors to instruct or characterize tissue biology.

147 movement of whiskers, a behavior that is not instructed or necessary in the task, can inform an obser

148 lls adopt tissue-specific characteristics to instruct organ development and regeneration(1,2).

149 obtrusively presented a cue that was used to instruct participant to avoid committing the locations o

150 o test voluntary, goal-directed attention we instructed participants to listen to a short story comin

151 item-based directed-forgetting procedure and instructed participants to memorize the location of some

152 It is suggested that we should instruct patients to inhaler DPI based on inspiratory re

153 Studies 2 and 3 show that instructing people to avoid the exponential growth bias

154 l markers, indicating that the CNS niche may instruct peripheral myeloid cells to gain the phenotype

155 hat localized MP expression is sufficient to instruct PIN1 polarity directions non-cell autonomously,

156 ed stimulus must act as a teaching signal to instruct plasticity of the conditioned stimulus represen

157 ive in generating salient signals useful for instructing plasticity and learning.

158 w lineage-specific transcription factor that instructs PN dendrite targeting.

159 in the cell cycle, whereas centrosomal AIR-1 instructs polarity initiation thereafter.

160 BMP7 instructs precursor cells to differentiate into LCs that

161 es and suggest that central amygdala neurons instruct predatory hunting across jawed vertebrates.

162 bly is that peripheral, target-derived, cues instruct pSN identities and patterns of intraspinal conn

163 published in the 2D and 3D radiotherapy era instructed radiation oncologists to avoid dose inhomogen

164 athogens by innate and adaptive immune cells instructs rapid alterations of cellular processes to pro

165 h dose of LPS, exposure to a low dose of LPS instructed recruited neutrophils to upregulate their exp

166 kin with antigen-presenting cells capable of instructing recruited cells to elicit their effector fun

167 Moreover, a large fraction of Notch-instructed regulatory loops form highly interacting enha

168 we found that learning rates were reduced in instructed, relative to free, choices.

169 essings were applied by nursing staff (or by instructed relatives for some outpatients).

170 ich disease-associated environmental signals instruct resident and recruited macrophages to acquire d

171 al acidic sorting motifs in AATs and thereby instructs Rsp5 to ubiquitinate proximal lysine residues.

172 In a fifth data-set using instructed rules, this bias was strong enough to counter

173 for conditions requiring the memorization of instructed S-R rules for correct performance.

174 ccadic reaction times, depending on the task-instructed saccade, while rostral stimulations of 8Av/45

175 Enzyme-instructed self-assembly (EISA) represents a dynamic con

176 Occurring between HS-5 cells, such an enzyme-instructed self-assembly enables a sheet of the HS-5 cel

177 As the first example of the enzyme-instructed self-assembly of a synthetic peptide for traf

178 How OFC encodes decision variables and instructs sensory areas to guide adaptive behaviour are

179 ng molecules CCL9 and IL-23 as the principal instructing signals for stromal reprogramming.

180 gering food choices even when not explicitly instructed.SIGNIFICANCE STATEMENT The expectation of tas

181 geting and polymer chemistry, we genetically instructed specific living neurons to guide chemical syn

182 Descending command neurons instruct spinal networks to execute basic locomotor func

183 findings, and revealed that both pooled and instructed spot sputum collections were similarly effect

184 y brought their beta oscillatory power to an instructed state and subsequently executed an arm reach.

185 nment, triggering production of signals that instruct stem cell fate choices.

186 However, the signaling cues that instruct stereotyped neurite pruning are yet to be fully

187 Here we show that Wnt morphogen instructs stereotyped neurite pruning for proper neurite

188 Attention was manipulated by instructing subjects to attend to tones in one ear only,

189 the onset of food allergies in offspring by instructing T reg formation via neonatal Fc receptor (Fc

190 Although the mechanisms by which they instruct TH2 differentiation are still poorly understood

191 hich PKC-theta drives innate immune cells to instruct TH2 responses in patients with allergic lung in

192 We tested whether Purkinje cells instruct the assembly of inhibitory projections into zon

193 DNA (or potentially a simplified genome) to instruct the cell to carry out novel, specific tasks.

194 ion of the forelimb initiation gene Tbx5 and instruct the definitive position of the forelimb.

195 city and drug delivery assessment, which may instruct the design of safe nanomaterials and more effec

196 oxygen gradient generated in our device can instruct the establishment of a functional metabolic zon

197 al brain sections from patients with SLE may instruct the evaluation of ongoing clinical trials of an

198 , while cytokine signaling has been shown to instruct the fate of progenitor cells.

199 Our studies reveal that Act-A-iTreg cells instruct the generation of a highly effective immunoregu

200 l reveal that the adaptive immune system can instruct the innate response to adenovirus infection.

201 M) development, has been shown to be able to instruct the lineage choice of uncommitted granulocyte M

202 on silencing; namely, how RNAs are chosen to instruct the piRNA machinery in the nature of its silenc

203 orrelation-based plasticity mechanisms could instruct the precise spatiotemporal selectivity that und

204 Which cues instruct the refinement of excitatory inputs, calcium si

205 tivation and might be necessary for ILC2s to instruct the TH2 response.

206 is until the emergence of patterned activity instructing the earliest spontaneous motor behavior.

207 ion refines and maintains row identity, thus instructing the form of the bundle.

208 Our results show how E-cadherin instructs the assembly of the LGN/NuMA complex at cell-c

209 enger complex (CPC) and centralspindlin that instructs the cleavage furrow.

210 Thus, IL-33 instructs the development of RPMs as a response to physi

211 d suggest a model whereby the dominant input instructs the development of the weaker input.

212 in with a single immunoglobulin (Ig) domain, instructs the distinct, neuron-type-specific elaboration

213 ts that neural activity during fear learning instructs the formation of new myelin, which in turn sup

214 Here, we show that the cytokine activin-A instructs the generation of CD4(+) T cells that express

215 was hypothesised that DBN protein abundance instructs the integrity and function of synapses.

216 providing evidence that innate connectivity instructs the later refinement of cortex.

217 d that the diameter of the source epithelium instructs the morphology of growing tumours.

218 Together, these data suggest that LKB1 instructs the timing and location of connectivity in the

219 ion of the Nrp2 gene in MCs is sufficient to instruct their circuit formation from the PV MOB to the

220 HPV-transformed cells actively instruct their microenvironment, promoting chronic infla

221 way impinges upon various organ primordia to instruct their side-specific development.

222 ular milieus where they receive signals that instruct them to invade their target tissues.

223 with a smartwatch (Apple Watch Series 0) and instructed them to wear it daily, which measured their h

224 o a mindfulness instruction (MT) group or an instructed thinking (IT) group.

225 rse wing genes are functionally required for instructing this process; and that, in the absence of Ho

226 cated that the transfer of observational and instructed threat learning involved different computatio

227 system in which basement membrane stiffness instructs three-dimensional tissue morphogenesis.

228 n and unique mechanisms by which macrophages instruct tissue repair in the liver, nervous system, hea

229 fness gradient in the Drosophila egg chamber instructs tissue elongation.

230 ergy with tumor-redirected lymphocytes, they instructed TNFalpha expression, endothelial cell activat

231 ms after the green LED; participations were instructed to abort the button release on these trials.

232 Twelve participants (instructed to act in three prescribed ways) manually con

233 During 2 wk, the participants were instructed to adhere to a controlled diet based on ITF-r

234 igraph at home and in the hospital, and were instructed to adhere to their regular sleep schedule.

235 Participants undergoing fMRI were instructed to appraise how much they liked a set of prod

236 aining 1450 ppm fluoride (control), and were instructed to brush with the assigned toothpaste twice/d

237 Participants were instructed to close their eyes during the experiment for

238 The institutions were instructed to collect data on 6-hour bundle compliance a

239 art of the experiment, amputee subjects were instructed to communicate verbally with one prosthetist

240 74% were instructed to consult an allergologist for adequate diag

241 Participants were instructed to consume >=2 servings/d of Plant compared w

242 ive or negative news to camera, but were not instructed to deliberately or artificially pose any spec

243 During retrieval, subjects were instructed to differentiate among new, old, and altered

244 Participants were instructed to discriminate between the standard and oddb

245 Participants were instructed to doff PPE as they would in routine practice

246 Patients were instructed to dose at home within 4 h of onset of migrai

247 nt advances on how cell bodies and axons are instructed to either cross or respect this boundary, and

248 vidual yawning and, in separate blocks, were instructed to either resist yawning or allow themselves

249 y; thus, program directors were specifically instructed to exclude any preliminary residents in their

250 experimental conditions where subjects were instructed to expect the same CS-US contingencies while

251 Observers were instructed to fixate a visual target while gaze directio

252 Participants were instructed to flex their elbow to 90 degrees while tensi

253 5 targets of varying size and value and were instructed to harvest as much reward as possible by eith

254 Subjects with chronic insomnia were instructed to hold the device in each hand for 8 mins fo

255 d that clothing cues are non-informative and instructed to ignore the clothes (in one study, with con

256 rd, punishment, or control feedback and were instructed to ignore the presence of the sequence, i.e.,

257 lowed the same design, but participants were instructed to intentionally learn the sequence.

258 DMT and (separately) placebo (saline) while instructed to keep their eyes closed.

259 When instructed to lead the interaction, high and low EPT lea

260 ehavioural performance when participants are instructed to learn in a goal-directed fashion (i.e. int

261 A wait-list control group was instructed to maintain their usual activities during the

262 rdized self-tonometry training and were then instructed to measure their own IOP under observation.

263 of "syllables." We found that when birds are instructed to modify a syllable in one sequential contex

264 ents with drug-resistant focal epilepsy were instructed to overtly explain, in a sentence, 'what is i

265 The CD group was instructed to perform exercises 5 times per week or more

266 intermediate phalanges; only one finger was instructed to produce force at a time.

267 Even though instructed to rate the specific images, not the people,

268 dulated by the target to which subjects were instructed to reach (target effect).

269 Participants were instructed to react as quickly and accurately as possibl

270 Participants were instructed to release a button following a green LED fla

271 cipants viewed a series of pictures and were instructed to remember or forget each one.

272 Subjects were instructed to remember short lists of sequentially prese

273 After 21 days, patients were instructed to resume proper home oral hygiene procedures

274 Patients initiated on ART were instructed to return at 6 and 12 months post-initiation

275 Patients referred to pre-ART care were instructed to return every 6 months for CD4 monitoring.

276 Patients were instructed to return to clinic for routine follow-up at

277 All individuals were instructed to rinse with their respective mouthwash twic

278 man participants (both male and female) were instructed to saccade toward a face or a house that, on

279 lower in upper layers when the animals were instructed to suppress a saccade toward a peripheral sti

280 ade available to each patient, and they were instructed to take it as necessary.

281 e lymphoblastic leukemia (ALL) are generally instructed to take mercaptopurine (6-MP) in the evening

282 enhanced when the participant was explicitly instructed to take the other person's perspective, but r

283 Patients were instructed to take the product orally twice daily for si

284 ontrolled by a stochastic decision in R7 and instructed to the underlying R8.

285 orally disintegrating tablet) or placebo and instructed to treat a single migraine attack of moderate

286 LT, patients randomized into each group were instructed to use an unmarked drop 4 times daily startin

287 Each subject was instructed to use the fingertip of their dominant hand's

288 Patients were instructed to use the study drug as needed for off perio

289 ly participants in the intervention arm were instructed to weigh themselves daily and told that they

290 tor the external environment, and in health, instruct tolerance to innocuous inhaled particles while

291 The genetic information that instructs transcription and other cellular functions is

292 On instructed trials, the reach goal was determined by a se

293 rsal-learning task, with intermixed free and instructed trials.

294 Thus, environmental cues instruct TRMs to express CRIg, which functions as an imm

295 We further show that pericyte derived Cyr61 instructs tumour cells to elevate expression of the proa

296 n the strategy task, we used a visual cue to instruct two male rhesus monkeys either to repeat their

297 xternal cues forms the basis for how tissues instruct type 2 immunity.

298 Two rhesus monkeys conducted instructed walk-and-reach movements towards targets flex

299 lus task epoch in which the animals had been instructed which of these two tasks to perform but befor

300 talk between the BMEC niche and HSPCs, which instructs young HSPCs to behave as aged HSPCs.