ライフサイエンスコーパス: insufficient

1 .08]; P = .49; 2 studies; 175 patients; SOE, insufficient).

2 .39]; P = .15; 9 studies; 833 patients; SOE, insufficient).

3 nderstanding of these dynamics is frequently insufficient.

4 veness and harms of screening for anxiety is insufficient.

5 Across 26 trials, the evidence was largely insufficient.

6 because financial resources and capacity are insufficient.

7 , meaning that blood-based monitoring may be insufficient.

8 Here model calibration was insufficient.

9 his collective action problem, but is likely insufficient.

10 KD) are often 25(OH)D(3) and 1,25(OH)(2)D(3) insufficient.

11 Evidence was mostly insufficient about prescription drugs for BPSD and about

12 s grown in the Mediterranean basin reveal an insufficient accumulation of anthocyanins and thus a sca

13 Current literature suggests insufficient accuracy of endoscopic biopsies, EUS, and 1

14 mbinations of cycling myosin that contribute insufficient activation energy delay deactivation.

15 imary cause for the observed defects causing insufficient alignment of the OF margins in Nf2 mutants

16 recombination rate estimation are limited by insufficient amounts of informative genetic data or by h

17 ondition in which the thyroid gland provides insufficient amounts of thyroid hormone for the needs of

18 developmental stages and between tissues and insufficient amounts of total Pol III in vivo.

19 There were insufficient analyzable data for gadodiamide, gadoverset

20 y's mental (ill)health and the prevalence of insufficient and disrupted sleep.

21 We consider biases that can lead to both insufficient and excessive information-seeking.

22 However, these algorithms are limited by insufficient and incomplete annotation.

23 key populations and geographical regions is insufficient and research on intersectional stigma (ie,

24 ) containing unreacted PbI(2) has been still insufficient and, therefore, needs to be clarified for b

25 of endogenous revascularization after MI is insufficient, and MI can often result in ventricular rem

26 quality, the evidence on quality of life was insufficient, and the analyses for some outcomes were ba

27 parasite-derived nucleic acids are therefore insufficient as diagnostic tools or as biomarkers of tre

28 pace with resource phenology, they may prove insufficient, as evidenced by population declines in man

29 thods for photon recuperation are limited by insufficient bandwidth or parasitic absorption, resultin

30 Counting CPE or CPOs is better but still insufficient, because different carbapenemases have diff

31 Human islet isolates with insufficient beta-cell mass for implantation within 72 h

32 ndard treatment when volitional breathing is insufficient, but drawbacks include muscle atrophy, alve

33 ancing implemented in the United States, are insufficient by themselves in protecting the public.

34 andard raw sequence data pre-processing, and insufficient capabilities for integration with distribut

35 Insufficient capacity of cellular degradative systems, c

36 energy harvesting and conversion, but their insufficient charge transfer and rapid charge recombinat

37 Proteotoxicity from insufficient clearance of misfolded/damaged proteins und

38 early apoptosis leads to cell depletion and insufficient compensatory proliferation.

39 oil in low-salinity water is found to be an insufficient condition for wettability alteration in car

40 clinical care and public health service, and insufficient continuity of care throughout the entire he

41 Decades of insufficient control have resulted in unprecedented spre

42 o cause major epidemics and for which no, or insufficient countermeasures exist.

43 But, it gives insufficient credit to the possibility that the process

44 lth and low-resource settings is hampered by insufficient data diversity, nontransparent AI algorithm

45 Insufficient data exist in regard to gastrointestinal hi

46 with refractory cardiac arrest but there is insufficient data on the frequency of different types of

47 There was insufficient data to analyze other markers of neonatal m

48 g AMLs with macroscopic fat and studies with insufficient data were excluded.

49 Over 80% of patients remained VD insufficient/deficient.

50 er therapy but are sometimes associated with insufficient delivery resulting in sub-cytotoxic amounts

51 n, recent evidence indicates that this is an insufficient depiction of the risks and reservoirs.

52 anifestations in 901 patients, but many have insufficient detail, reflecting the challenge of studyin

53 suffer from methodological issues and report insufficient details to assess appropriateness of prescr

54 Insufficient dexterity, visual impairment, and cognitive

55 However, in the past, insufficient differentiation between cellular and cell-f

56 While at 12 months there was insufficient DNA for sequencing, by 24 months and 36 mon

57 ellular striatal dopamine levels rather than insufficient dopamine D2 receptor occupancy.

58 ity; (2) frequent antibiotic misuse; and (3) insufficient drinking water, drainage and sanitation inf

59 extended periods remains challenging due to insufficient drug loading capacity and drug-device inter

60 However, current approaches show insufficient drug-loading capacity and inefficient drug

61 ascular or open revascularization in case of insufficient effect.

62 electrodes in optoelectronic devices, their insufficient electrical conductivity, low work function,

63 Our data suggest that this is due to insufficient electron flux to the V-nitrogenase isoform

64 s currently under investigation in patients, insufficient emphasis has been placed on formulation cha

65 ing points of convergence but also points of insufficient emphasis.

66 n suggests a key pathophysiological role for insufficient energy delivery, it is unclear how the netw

67 ncluding the absence of ERBB2 amplification, insufficient ERBB2 activity for therapeutic sensitivity

68 There was also insufficient evidence about the impact of most anaphylax

69 g has been decreasing in many countries, but insufficient evidence exists on the adult hazards of hav

70 However, at present, insufficient evidence exists showing that SLNB improves

71 d components on clinical outcomes in RA, but insufficient evidence exists to provide specific dietary

72 Insufficient evidence exists to support the management o

73 uated interventions either had no benefit or insufficient evidence of benefit to draw conclusions on

74 ity-adjusted life year (QALY), but there was insufficient evidence of effect on other primary endpoin

75 this type of fracture has increased, despite insufficient evidence of improved outcomes over non-surg

76 There is insufficient evidence to conclude on the safety profile

77 We argue that there is currently insufficient evidence to establish meaningful ASD specif

78 Recent guidelines note insufficient evidence to quantify its natural history or

79 There is insufficient evidence to recommend for or against screen

80 There is insufficient evidence to recommend one particular trepon

81 At interim analysis, there was insufficient evidence to support continued accrual, and

82 The findings of insufficient evidence to support gene-disease associatio

83 BEST PRACTICE ADVICE 3: There is insufficient evidence to support the use of inflammatory

84 Although there is insufficient evidence to support the use of most approac

85 At this time, there is insufficient evidence to warrant inflammation adjustment

86 A putative mechanism is insufficient exposure to beneficial microbes early in li

87 and dogs from Tbilisi is probably caused by insufficient exposure to sand fly bites.

88 sion to endothelial cells as a necessary but insufficient first step for development of blinatumomab-

89 he import of water-intensive goods to offset insufficient food production driven by socioeconomic and

90 loped, but the resulting sensitivity remains insufficient for achieving in-depth coverage of proteomi

91 ug overdose epidemic will be beneficial, but insufficient for achieving pre-2010 pace of life expecta

92 standard treatments for DIC but are gravely insufficient for any of the TMA disorders that involve d

93 Because current evidence is insufficient for assessing the role of these tests in st

94 al Baltimore and Seattle diagnostic criteria insufficient for children.

95 chromosome, an organisation predicted to be insufficient for complete genome duplication within S ph

96 plying that high sequence identity alone was insufficient for cross-reactivity among the M peptides.

97 diation, the generated UV-C light fluence is insufficient for disinfection.

98 Thus, the quantum of evidence is insufficient for endorsing TAVR as the preferred interve

99 ch extent virgin material is substituted, is insufficient for evaluating the transition toward circul

100 Overall, the database is insufficient for FDA approval of any psychedelic compoun

101 ntial for GSIS; an increase in ATP alone was insufficient for GSIS.

102 is suggests that instantaneous optic flow is insufficient for heading perception in the presence of r

103 ut targeted to individuals are necessary but insufficient for lasting change.

104 prion-like domains, such characteristics are insufficient for making accurate predictions; thus, a pr

105 ary vein isolation (PVI) alone is considered insufficient for many patients with persistent AF.

106 Standard human reference viruses were insufficient for mapping diverse influenza samples in si

107 helps to explain why S-RNase alone could be insufficient for pollen rejection.

108 For MCC, one immune escape mechanism is insufficient for recognition by T cells owing to the dow

109 ancers, BRD4 D1 inhibition in MM.1S cells is insufficient for stopping Myc expression and may lead to

110 gested genomic cluster definitions alone are insufficient for targeted response.

111 Unfortunately, clinical suspicion is insufficient for the accurate diagnosis of group A strep

112 We also studied mice haplo-insufficient for the Na(+) channel Na(v)1.5 (Na(v)1.5(+/

113 of costimulatory molecules, is necessary but insufficient for this process.

114 tment-refractory, yet RAS mutation itself is insufficient for tumorigenesis, due in part to profound

115 We argue that the evidence remains insufficient for use of intraoperative radiotherapy (IOR

116 ion supporting that ageing is necessary, but insufficient, for AD occurrence.

117 .25-136.75) for an unadjusted UAS model with insufficient geographical coverage, and $34.09 (95% CI 2

118 se is a lysosomal storage disorder caused by insufficient glucocerebrosidase activity.

119 There is insufficient good-quality evidence to support current re

120 Currently, there is insufficient guidance for policymakers charged with esta

121 photochemistry of Hg(I) and Hg(II) leads to insufficient Hg oxidation globally.

122 These C-TMDs with insufficient hydrophobicity are post-translationally rec

123 main ineligible for hepatic resection due to insufficient hypertrophy of the FLR.

124 d mucosal immune dysfunction play a role for insufficient immune reconstitution in HIV infection inde

125 nderwater environment remains elusive due to insufficient impedance mismatch of state-of-the-art meta

126 urrent anti-inflammatory therapies are often insufficient in preventing or reversing these complicati

127 lected pathogens is often challenging due to insufficient information and absence of genetic tools.

128 Hence, in view of the insufficient information and contrasting results obtaine

129 BS delivered insufficient information in over one fourth of patients,

130 PET exam was requested, because BS provided insufficient information.

131 either beta-cell mass or function can cause insufficient insulin levels and, as a result, hyperglyce

132 Likewise, there is insufficient knowledge about the role of TLR4 in diabete

133 ty of teixobactin require modifications, yet insufficient knowledge on its binding mode impedes the h

134 xonomic and nomenclature problems related to insufficient knowledge on the spirochetes and their vect

135 g the science, including inadequate funding, insufficient knowledge to develop appropriate assays, an

136 f C-mannosyltransferase activity leads to an insufficient level of additional proteins.

137 While insufficient loading of TRF2 at shortened telomeres cont

138 r, for almost all bird populations, there is insufficient long-term monitoring to understand baseline

139 phatics undergo significant remodeling, with insufficient lymphatic function and/or lymphangiogenesis

140 We proposed that insufficient melatonin levels impair mitochondrial homeo

141 ng nucleosomes are low-fidelity replication, insufficient mismatch repair and increased double-strand

142 and species richness was greatly affected by insufficient monitoring, and could lead to incorrect con

143 ication, which can be perturbed by excess or insufficient Mov10.

144 pert Ultra has improved sensitivity, but has insufficient negative predictive value to exclude TBM.

145 or several prespecified moderators due to an insufficient number of studies.

146 Diabetes results from insufficient numbers of functional pancreatic beta-cells

147 It is now recognized that insufficient O(2) is not the primary basis for lactataem

148 d models concurrently in areas where we have insufficient observational data.

149 Evidence was mostly insufficient on drug treatment of BPSD and on supplement

150 mpatible protospacer adjacent motifs (PAMs), insufficient on-target activity and off-target effects.

151 ion, desorption, and diffusion processes are insufficient or in the wrong direction to produce the ob

152 Insufficient or low strength of evidence and applicabili

153 evidence reported in trials was judged to be insufficient or of low certainty for most harm outcomes.

154 or gene prioritization remains inconsistent, insufficient, or absent.

155 t PI3K activation for which immunotherapy is insufficient, or patients who are unsuitable for immunot

156 Mammalian cells respond to insufficient oxygen through transcriptional regulators c

157 mortality among older Mexican Americans with insufficient PA levels.

158 in either T(4)NDI or T(4)PE(2)NDI due to an insufficient PE(n) bridge length.

159 oblastoma multiforme (GBM) is constrained by insufficient penetration across the blood-brain barrier

160 nment because of high metabolic activity and insufficient perfusion.

161 ranscriptase inhibitors is often hampered by insufficient phosphorylation.

162 ave been used to identify these species, but insufficient phylogenetic signal was available.

163 While insufficient Plk1 levels lead to the formation of shorte

164 There are insufficient population-level data on the effects of pri

165 trate the inner decision-making process; the insufficient power of classical computing; and the negle

166 bgroups (e.g., LAA), which could have led to insufficient power to detect significant trends.

167 interpretation is subjective and can render insufficient precision, making it difficult to apply a t

168 an appropriate balance between excessive and insufficient procedural safeguards.

169 activity loss in CO(2) reforming processes, insufficient product selectivity in thermocatalytic CO(2

170 equate records, unsatisfactory curation, and insufficient public knowledge of relevant collections; 2

171 ty of influent chemical contaminants and the insufficient rejection of low-molecular-weight neutral o

172 Risk of bias and insufficient reporting present challenges to the reprodu

173 itive to shallow (<5 km) storage and/or have insufficient resolution at these depths.

174 mmHg to 14.0 +/- 1.6 mmHg for patients with insufficient response to 360 degrees SLT treatment (p =

175 thium-ion batteries (LIBs), limited by their insufficient reversible capacity, short cyclability, and

176 ground (n = 5), high RNA background (n = 1), insufficient RNA read depth (n = 3), or quality control

177 ting working memory, and (3) demonstrate how insufficient sample size and task duration reduce the li

178 , did not improve these estimates because of insufficient sample size or selection biases.

179 ion to recommendations for further research, insufficient sample size was the most predominant method

180 However, their insufficient selectivity and activity remain grand chall

181 any years; however, these methods often have insufficient selectivity for practical application.

182 mines core moderators (e.g., uncertainty and insufficient self-correction) and mediators (e.g., exter

183 Skin snip evaluation for onchocerciasis has insufficient sensitivity when skin microfilarial (mf) de

184 ell behavior, but it is currently limited by insufficient sensitivity.

185 In the long-term, chronic insufficient sleep and circadian rhythm disorders have b

186 ular, and cognitive health often result from insufficient sleep and/or circadian misalignment.

187 , lack of exercise, psychosocial stress, and insufficient sleep are increasingly prevalent modifiable

188 ntia have also been associated with chronic, insufficient sleep.

189 tomography or ultrasound is limited by their insufficient spatial resolution.

190 flexibility have been demonstrated but show insufficient stability in air and moist environments due

191 e to high sequence conservation, toxicity or insufficient stability of the target protein.

192 The 45 studies had insufficient statistical power to compare the techniques

193 receiving cholinesterase inhibitors, low- to insufficient-strength evidence suggested that, compared

194 e services were often overlooked or provided insufficient support when accessed by survivors.

195 ed by interior hypoxia and cell death due to insufficient surface diffusion, preventing generation of

196 as diabetes, hypertension, and obesity, and insufficient surveillance on and coordination of our foo

197 s remaining in the field of drug delivery is insufficient targeting of diseased tissues or cells.

198 used for this task have been developed with insufficient thoughtfulness into the datasets on which t

199 ese clinical applications are limited due to insufficient tissue compatible donors, side effects of e

200 n only recent observations will therefore be insufficient to accurately characterise flood hazard ris

201 tions, although behavioral methods alone are insufficient to accurately identify what kind of sleep i

202 g low carbon steelmaking technology alone is insufficient to achieve the emissions cut; conversely, r

203 the degree of reservoir clearance was still insufficient to achieve viral control.

204 Low or transient force was insufficient to activate these pathological changes, whe

205 SPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms

206 SPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms

207 SPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms

208 dults are uncertain and that the evidence is insufficient to assess the balance of benefits and harms

209 SPSTF concludes that the current evidence is insufficient to assess the balance of benefits and harms

210 Population immunity appears to be insufficient to avoid a second wave if all control measu

211 ities reported by others, bond formation was insufficient to balance drag forces on an early thrombus

212 n incidence and the fact that virus alone is insufficient to cause disease, suggests other co-factors

213 Intriguingly, low levels of endotoxin, insufficient to cause donor lung injury, promoted TRAM-d

214 ccur early in pre-neoplastic lesions but are insufficient to cause PDA.

215 study demonstrates that diffraction alone is insufficient to characterize the phase composition of MA

216 rations with 25 mg once daily appeared to be insufficient to completely inhibit FAAH activity which m

217 ident in time with mainshock energy alone is insufficient to conclude that dynamic triggering occurre

218 omplexes (averaging 3 per cohort), which are insufficient to confer cohesion but can bind to individu

219 nents of the metabolic syndrome appear to be insufficient to control cancer development in subjects w

220 n provide control for proximal joints, it is insufficient to control either hand or coordinated shoul

221 However, such broad-scale alterations are insufficient to define the minimal requirements for doma

222 ver, expression of the RPS28B 3'UTR alone is insufficient to drive PB assembly.

223 of social interaction found in Drosophila is insufficient to drive population-level behavioral asymme

224 ndicating that MALT1 scaffolding activity is insufficient to drive the cytokine response and that MAL

225 ung and pancreatic cancer, oncogenic KRAS is insufficient to drive tumorigenesis, while addition of m

226 The isradipine dose may have been insufficient to engage the target calcium channels assoc

227 shown that JAK or PI3K pathway inhibition is insufficient to eradicate the most common cytokine recep

228 ography, CT and MRI, as biomarkers alone are insufficient to establish a diagnosis despite their role

229 Pharmacokinetic monitoring is insufficient to estimate the intensity of immunosuppress

230 has demonstrated that parametric models are insufficient to explain and predict microbial response u

231 erefore, inhibition of Jak-STAT signaling is insufficient to explain inhibition of IFN-beta promoter

232 suggests that Na+ channel effects alone are insufficient to explain the efficacy of flecainide.

233 for choosers suggests that 'good genes' are insufficient to explain the evolution of mate choice or

234 apid adjustment and surface mean warming are insufficient to explain the time evolution of the hydro-

235 These effects were however insufficient to facilitate significant recovery in algal

236 hat mammalian SRP and SRP receptors (SR) are insufficient to generate the biologically required speci

237 Available biomarkers are insufficient to guide individual patient prognosis or th

238 Current guidelines and literature are insufficient to guide physicians regarding the initiatio

239 hat gene-expression analysis in isolation is insufficient to identify neuron types and have important

240 rRNA. However, a heterozygous Bccip loss was insufficient to impair 60S biogenesis in mouse embryo fi

241 compared to unimplanted probes, but this was insufficient to impair future single-unit recordings.

242 , haploinsufficiency of c-Cbl(+/-) alone was insufficient to induce tumorigenesis regardless of an in

243 Moreover, loss of membrane integrity is insufficient to induce type I IFN production.

244 , pharmacological inhibition of OTR alone is insufficient to induce vigilance in unstressed mice, sug

245 Sensitivity in asymptomatic individuals was insufficient to justify its use as a first-line screenin

246 s of climate change, predator plasticity was insufficient to keep pace with prey phenology.

247 s evidence that current interventions remain insufficient to keep virus transmission under control in

248 Evidence is insufficient to make evidence-based recommendations abou

249 However, grid decarbonization will be insufficient to meet the 80% emissions reduction target

250 ive levels of Nrf2 in the premature lung are insufficient to mitigate hyperoxia-induced hypoalveolari

251 stewater-derived CECs, but dilution alone is insufficient to mitigate risks of localized inputs.

252 ntigen induces high-antibody titers that are insufficient to neutralize diverse HCV isolates.

253 y of a single secondary structure element is insufficient to obtain high binding affinities.

254 However, restoration often remains insufficient to offset that loss.

255 The data were insufficient to pool the results for waist-to-hip ratio

256 ealed that the presence of Ras mutations was insufficient to predict sensitivity to Ras inhibition, s

257 Although VRC01 levels were insufficient to prevent a resurgent infection, knowledge

258 t level of herd immunity in livestock may be insufficient to prevent another large outbreak, should s

259 , the reduction in AEC appeared to have been insufficient to prevent post-treatment AEs.

260 These pervasive mechanisms are insufficient to prevent viral inhibition completely but

261 of rare ophthalmic conditions, but alone are insufficient to provide evidence for changing clinical p

262 endogenous concentrations of haptoglobin are insufficient to provide protection against Hb-driven dis

263 tilators if the supply of these resources is insufficient to provide them to all patients considered

264 Data are insufficient to recommend PARP inhibitor use in the earl

265 ogical health and crop N response to date is insufficient to reliably drive conservation policy and i

266 We concluded that existing tools are insufficient to reliably predict post-intensive care syn

267 of emissions, absent of individual PCFs, is insufficient to reliably quantify carbon emissions, and

268 The inhibition of caspases was insufficient to rescue cell viability of autophagy-repre

269 arisons of treated and untreated samples are insufficient to resolve the effects of disrupting two or

270 rmeability and retention (EPR) effect remain insufficient to satisfy the clinical need, and the chall

271 for genotype-by-environment interactions is insufficient to support a strong inference of decanaliza

272 indicating that RAS binding to p110gamma is insufficient to support GPCR activation in this cell typ

273 g E3 to membranes in the absence of WIPI2 is insufficient to support LC3 lipidation, demonstrating th

274 phagocytes and suggest that proliferation is insufficient to sustain generations of macrophages durin

275 suggest that plant NUE responses are likely insufficient to sustain observed greening trends in NGP

276 threshold by ~15%, an effect size which was insufficient to systematically decrease OSA severity as

277 However, current methods are insufficient to test hypotheses that concern physical pr

278 Pulmonary vein isolation is insufficient to treat all patients with persistent atria

279 Current applications of lactose are insufficient to use the recovered lactose from manufactu

280 ant step to solve the fundamental problem of insufficient training data in deep learning.

281 ing (MTL) approach for predicting spectra of insufficient training samples, which allows our model to

282 K9me3 spreading over bdH3K4me3, resulting in insufficient transcriptional activation of genes, endoge

283 Shortened telomeres recruit insufficient TRF1 and as a consequence inadequate tankyr

284 However, insufficient understanding and investigation of key fact

285 matory bowel disease (IBD), due, in part, to insufficient understanding of disease-site, protein-leve

286 ive drug combinations is limited, in part by insufficient understanding of how the transcriptional re

287 However, insufficient understanding of intra-cell-wall diffusion

288 Nevertheless, an insufficient understanding of structure-activity relatio

289 ontrol is yet to be fully realized due to an insufficient understanding of the governing nucleation a

290 gs which may, in part, be attributable to an insufficient understanding of the relationship between f

291 precision is highly demanding, mostly due to insufficient understanding of the self-assembly process

292 ecause of the limited synthesis approach and insufficient understanding of the structure-property rel

293 s still as high as 50%, which stems from our insufficient understanding of the underlying mechanisms

294 ve limitations, particularly APT, because of insufficient understanding of void imaging.

295 Insufficient vaccine doses and the lack of therapeutic a

296 ng process is accelerated, and the factor of insufficient vacuum in FT ICR mass spectrometers with an

297 however, can be metabolically hostile due to insufficient vascular exchange and cancer cell metabolis

298 als, or it can make a model appear generally insufficient while it actually works well in specific su

299 owever, standard immunization strategies are insufficient with increasing age due to immunological im

300 tion that has conventionally been impeded by insufficient yield and low enantiomeric excess.