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1  on this finding, we characterized the Fab-6 insulator element.
2  CCTC-binding factor CTCF bound to the c-myc insulator element.
3 erized silencing activity we measured in the insulator element.
4 he beta-globin locus, including the upstream insulator element.
5 rom chromosomal position effects by flanking insulator elements.
6 s when the transcription unit was flanked by insulator elements.
7 s of H3 acetylation are present over the HS4 insulator elements.
8 ancer blocking activity, a characteristic of insulator elements.
9  of intergenic distance and configuration of insulator elements.
10  stem cells without the need for boundary or insulator elements.
11                The chicken beta-globin 5'HS4 insulator element acts as a barrier to the encroachment
12                                              Insulator elements affect gene expression by preventing
13                      Chromatin boundaries or insulator elements affect the interaction between enhanc
14 cent SIX5 regulatory region extends into the insulator element and is converted into 21 nucleotide (n
15  repeats are a component of a CTCF-dependent insulator element and that repeat expansion results in c
16 hromatin interactions, both between the CTCF insulator elements and between the LCR distal enhancer a
17 kb flanked by CTCF-binding enhancer-blocking insulator elements and is regulated by cell-type-specifi
18                                              Insulator elements and matrix attachment regions are ess
19               We compare Fab-7 to the su(Hw) insulator element, and show that Fab-7 enhancer blocking
20 is report we show that both CTCF and the HS4 insulator element are incorporated in the matrix; HS4 in
21                                  Boundary or insulator elements are emerging as key players in the es
22                Because transgenes flanked by insulator elements are shielded from position effects in
23                                          The insulator element at the 5' end of the chicken beta-glob
24 al role for CTG/CAG repeats as components of insulator elements at multiple sites in the human genome
25 The CCCTC-binding factor, CTCF, binds to the insulator elements at the 5' and 3' boundaries of the lo
26  sites that flank the CTG repeat and form an insulator element between DMPK and SIX5.
27  promoter sequence to interact with and that insulator elements block further tracking of enhancers.
28  to restrict enhancer action is a feature of insulator elements, but unlike previously described insu
29                                              Insulator elements can act as barriers to the spread of
30 it for two copies of the chicken beta-globin insulator element, (Ch beta GI)(2), in mice.
31 t not all CTCF sites genome-wide function as insulator elements, depending on cellular and genomic co
32 h an internal cellular promoter and flanking insulator elements did not activate the LMO2 gene.
33 of nearby endogenous genes reveals that CTCF insulator elements do not completely abrogate reporter e
34 ologous Drosophila melanogaster scs and scs' insulator elements do not require chromosomal context to
35 CTC-Binding Factor (CTCF) binding site on an insulator element downstream of the MMP8 gene (IE8) in t
36 ulatory element interactions with the MHC-II insulator elements, events that are required for maximal
37                              Addition of the insulator element from 5'HS4 of the chicken beta-globin
38                Transcriptional "border," or "insulator," elements have been implicated in mediating t
39 ding sites, RNA polymerase II regulation and insulator elements; however, comprehensive annotation of
40 ons, quite different from those of the gypsy insulator element in Drosophila, may generate similar lo
41 uggest that the maternal ICR functions as an insulator element in regulating mutually exclusive expre
42 n the chicken beta-globin hypersensitivity 4 insulator element in the vector generating truncated mRN
43 e functionally similar to chromatin boundary/insulator elements in metazoans that delimit functional
44 obal epigenetic alterations at enhancers and insulator elements in prostate and breast cancer cells u
45 ix attachment regions (MARs) can function as insulator elements in vivo.
46 ata indicate that human MARs can function as insulator elements in vivo.
47 irst example of chromatin domain boundary or insulator elements in yeast.
48 sv exhibits significant cobinding to class I insulator elements, indicating that it may also contribu
49 riginal LTR-GFP cassette with one flanked by insulator elements leading to a several fold reduction i
50  DNA methylation controls the activity of an insulator element located between the two linked genes b
51     We explored the clinical relevance of an insulator element located within the Chr11q22.2 locus, d
52 te receptor region, which suggests that this insulator element may harbor a high concentration of his
53                This region harbors the c-myc insulator element (MINE), which contains at least two ph
54                                     A single insulator element partially blocks enhancer-activated tr
55                                              Insulator elements play a role in gene regulation that i
56 n and chromatin interaction data to identify insulator elements potentially associated with MMP gene
57 ay be due to the incorporation of Drosophila insulator elements (SCS and SCS') into the transgenic ve
58 titutive focus of hyperacetylation at the 5' insulator element separating the globin locus from the f
59                                  Boundary or insulator elements set up independent territories of gen
60  map to DNA elements that resemble classical insulator elements: short genomic regions sensitive to D
61 ing (SIN) lentiviral vectors with or without insulator elements should provide a safe and effective t
62 he integrated reporter gene is surrounded by insulator elements, stably transformed cell lines displa
63 er communication in Abdominal-B by bypassing insulator elements such as Frontabdominal-7 and Frontabd
64 d by the tandem arrangement (pairing) of the insulator elements, suggesting that interactions between
65 foamy virus long terminal repeats contain an insulator element that binds CCCTC-binding factor and re
66      We propose that the RO is a specialized insulator element that organizes the tandem array of rRN
67 sy retrotransposon of Drosophila contains an insulator element that represses enhancer-promoter inter
68 and the transcripts do not spread across the insulator elements that delineate the iab regions.
69 moters, but their activity is constrained by insulator elements that prevent indiscriminate activatio
70  found to be associated with transcriptional insulators, elements that are associated with the organi
71 or elements, but unlike previously described insulator elements the RO does not block enhancer action
72 rom chromosomal position effects by flanking insulator elements, the suppressor Hairy-wing protein bi
73        The Drosophila Abdominal-B locus uses insulator elements to organize its large regulatory regi
74  genome complexity necessitates boundary and insulator elements to partition genomic content into dis
75 grated multigene vectors by incorporation of insulator elements to prevent promoter interference seen
76 K562 cell line confirmed the ability of cHS4 insulator elements to protect DsRed and IHK-beta-globin
77                To accomplish this, the gypsy insulator element was used to block bidirectional action
78           We determined that the presence of insulator elements was not required for reporter gene ex
79 elatively well studied, the full spectrum of insulator elements which bind the CCCTC binding factor (
80 sites [su(Hw)BSs] are potent transcriptional insulator elements which can block enhancer action, as w
81 rmethylation susceptibility of enhancers and insulator elements, which in turn may contribute to an a