ライフサイエンスコーパス: insulin-secreting cell

1 t and human intestinal epithelial cells into insulin-secreting cells.

2 of cyclic adenosine monophosphate (cAMP) in insulin-secreting cells.

3 ing intestinal cells into glucose-responsive insulin-secreting cells.

4 re competent to generate glucose-responsive, insulin-secreting cells.

5 echanism to a specific perinuclear region of insulin-secreting cells.

6 ) channels in human beta cells and rat INS-1 insulin-secreting cells.

7 fferentiate the acinar-like AR42J cells into insulin-secreting cells.

8 Ca(2+)-activated K(+) (SK) channel genes in insulin-secreting cells.

9 We tested the methods with glucagon- and insulin-secreting cells.

10 endent K+ current (IK(Ca)) in mouse betaTC-3 insulin-secreting cells.

11 y intracellular beta-NAD+, present in CRI-G1 insulin-secreting cells.

12 hat leptin (0.3-10 nm) hyperpolarizes CRI-G1 insulin-secreting cells.

13 olbutamide-sensitive KATP channels in CRI-G1 insulin-secreting cells.

14 and stimulate insulin secretion from CRI-G1 insulin-secreting cells.

15 ed propensity for conversion into functional insulin-secreting cells.

16 In insulin secreting cells a surprisingly large fraction of

17 entiation of human embryonic stem cells into insulin-secreting cells, achieving an elusive goal for r

18 -cells, and overexpression of CTSH protected insulin-secreting cells against cytokine-induced apoptos

19 d IK1 (SK4) are expressed in islet cells and insulin-secreting cells and are able to influence glucos

20 lation, protein expression, and stability in insulin-secreting cells and isolated rodent islets of La

21 s establish novel actions for NA and G(z) in insulin-secreting cells and possibly other cell types.

22 ties but also notable differences between S7 insulin-secreting cells and primary human beta cells.

23 s possible to convert adult fibroblasts into insulin-secreting cells, avoiding both a stable pluripot

24 ntration of free ADP in betaHC9 hyperplastic insulin-secreting cells based on the cell diameter and o

25 pithelial cells could be differentiated into insulin-secreting cells by exposing them to GLP-1.

26 In insulin-secreting cells, catechol estrogens produced rap

27 ively low endogenous Spl expression level in insulin-secreting cells contributes to their extraordina

28 Transplantation of pancreatic progenitors or insulin-secreting cells derived from human embryonic ste

29 ating the mitochondrial apoptotic pathway in insulin-secreting cells during ER stress.

30 Overexpression of SOX4 in the human insulin-secreting cell EndoC-betaH2 interfered with gran

31 In insulin-secreting cells, expression of NADPH oxidase (NO

32 regulated methylation-demethylation cycle in insulin-secreting cells, findings that may imply an impo

33 provides hope for self-renewal of functional insulin-secreting cells following beta-cell failure, a h

34 ategies to provide a replenishable supply of insulin-secreting cells for the treatment of diabetes me

35 ntify a ROCKII inhibitor H1152 as increasing insulin secreting cells from hPSCs and improving beta-ce

36 We show here that insulin-secreting cells from a homogeneous group of five

37 e miR-29 binding site on Mcl1 mRNA protected insulin-secreting cells from apoptosis triggered by miR-

38 en possible to generate abundant and durable insulin-secreting cells from human gut tissues to evalua

39 We show that silencing of DIMT1 in insulin-secreting cells impacted mitochondrial function,

40 ve beta-like cells similar to the endogenous insulin-secreting cells in mice.

41 ypeptide, which is implicated in the loss of insulin-secreting cells in type II diabetics.

42 ore active than the upstream promoter (A) in insulin-secreting cells (INS-1) and HeLa cells.

43 brane permeability of 8-pCPT-2'-O-Me-cAMP in insulin-secreting cells is so low as to limit its biolog

44 ion ([Ca2+]i) in apoptosis in MIN6 cells, an insulin secreting cell line, and in mouse islets.

45 ne prior study of human beta-cells and a rat insulin-secreting cell line (INS-1 cells) in which it wa

46 or genetic ablation of beta-arrestin 2 in an insulin-secreting cell line and mouse pancreatic islets,

47 e electrofusion-derived, glucose-responsive, insulin-secreting cell line BRIN-BD11 using patch-clamp

48 cells (GLUTag) and in vivo in mice using the insulin-secreting cell line INS-1 832/13 as reference.

49 ion efficiency as wild type channels, in the insulin-secreting cell line INS-1.

50 ic reticulum Ca2+ stores was assessed in the insulin-secreting cell line INS-1.

51 Using the insulin-secreting cell line INS-1E, we found that glucos

52 K(ATP) channels in BRIN-BD11 cells, a novel insulin-secreting cell line produced by electrofusion te

53 NES2Y is a proliferating human insulin-secreting cell line that we have derived from a

54 COX-1 and COX-2 mRNAs in MIN6 cells, a mouse insulin-secreting cell line, and in primary mouse and hu

55 (beta-NAD+)-activated ion channel in the rat insulin-secreting cell line, CRI-G1.

56 either bovine chromaffin cells or the INS-1 insulin-secreting cell line.

57 l alpha1-subunit derived from INS-1, the rat insulin-secreting cell line.

58 -stimulated insulin secretion (GSIS) in both insulin-secreting cell lines (INS-1 and MIN6) and mouse

59 The effect was observed in two different insulin-secreting cell lines and in rat pancreatic islet

60 Insulin-secreting cell lines encapsulated in alginate-ba

61 tudies in our group are directed at creating insulin-secreting cell lines that simulate the performan

62 es have been studied using rodent islets and insulin-secreting cell lines, but very little is known a

63 sults from the autoimmune destruction of the insulin-secreting cells of the pancreas.

64 The encapsulation of insulin-secreting cells offers a promising strategy for

65 In insulin-secreting cells, rescue of both mutant channels

66 tups aiming at developing glucose-responsive insulin-secreting cells, such as pluripotent stem-cell d

67 cts in human pancreatic beta-cells and INS-1 insulin-secreting cells to mobilize Ca(2+) from intracel

68 duce pancreatic beta-cells; the loss of this insulin-secreting cell type underlies type 1 diabetes.

69 + (KATP) channels was examined in rat CRI-G1 insulin-secreting cells using patch clamp and fluorescen

70 on mesenchyme give rise to glucose-sensing, insulin-secreting cells when transplanted in vivo.

71 the use of hydrogels in the encapsulation of insulin secreting cells with a special emphasis on hydro

72 Treatment of insulin-secreting cells with unloaded DIANAs did not imp

73 rboxyl methylation of CDC42 in five types of insulin-secreting cells, without blocking GTPgammaS-indu