ライフサイエンスコーパス: integral

1 tudes in 12 leads; as well as QRS and T wave integrals.

2 etween groups (crushed, 192 [132-245] versus integral, 227 [184-254], P<=0.01).

3 Our findings reveal 45 integral and 51 peripheral membrane proteins re-routed b

4 We report measurements of state-to-state integral and differential cross sections for inelastic N

5 ity, peak relaxation velocity, velocity-time integral, and TDI-derived maximal relaxation rate were a

6 g failure patients, except for velocity-time integral, as follows: peak contraction velocity, 1.35 +/

7 tylation and deposition of H2A.Z variant are integral aspects of active transcription.

8 Integral beta-barrel outer membrane proteins (OMPs) func

9 ce sustained health promotion effects (Salud Integral Colombia [SI!

10 Sex-specific estrogen action is an integral component for generating these sex differences.

11 crobial symbionts have been considered as an integral component in thermal adaptation due to their di

12 First, oral health care must be an integral component of a health care system's essential s

13 FICANCE STATEMENT Neurochemical ageing is an integral component of age-related cognitive decline.

14 Our data support ipsilaterality as an integral component of bilaterality and highlight a posit

15 -term MOUDs, regardless of selection, are an integral component of care in patients hospitalized with

16 Measurement of pH is an integral component of chemical studies and process contr

17 Cholesterol is an integral component of eukaryotic cell membranes and a ke

18 Blood vessels (BVs) are considered an integral component of neural stem cells (NSCs) niches.

19 letion and subsequent inhibition of BMI1, an integral component of polycomb-repressive complex 1 (PRC

20 Protists, an integral component of soil microbiome, are one of the ma

21 n mouse lupus B cells, shows that RAB7 is an integral component of the B cell NF-kappaB activation ma

22 Genomes are an integral component of the biological information about a

23 etric distribution of phosphatidylserine, an integral component of the cell membrane and 'eat-me' sig

24 e extracellular, ligand-binding domain is an integral component of the desensitization process.

25 Genetic testing has become an integral component of the diagnostic evaluation of patie

26 Our data emphasize that beta-Arr2 is an integral component of the GIT1/eNOS/NO signaling pathway

27 TF), implicated in fork reversal, are not an integral component of the ICL repair, pointing to a diff

28 Neurons are an integral component of the immune system that functions t

29 phosphatase 2 A (PP2A), is repurposed as an integral component of the intasome to mediate HTLV-1 int

30 Human leukocyte antigen-DM (HLA-DM) is an integral component of the major histocompatibility compl

31 Surgery remains an integral component of the management of patients with es

32 Astrocytes are an integral component of the neurovascular unit where they

33 This led to the adoption of VMMC as an integral component of the President's Emergency Plan for

34 USP1-associated factor 1 (UAF1) is an integral component of the RAD51-associated protein 1 (RA

35 protein function and should be considered an integral component of the sensing apparatus.

36 nd near the core-shell interface, forming an integral component to the co-assembly, as corroborated b

37 Polymers are integral components of ASDs, but mechanisms by which pol

38 ells (smooth muscle cells and pericytes) are integral components of brain blood vessels that play imp

39 Turtles and tortoises (chelonians) have been integral components of global ecosystems for about 220 m

40 t as synthetic models of natural systems and integral components of photodynamic therapy, but their u

41 ed in this study suggest that astrocytes are integral components of the brainstem mechanisms that pro

42 utonomous timing in the SCN, identifying the integral components of the clock.

43 cesses, ATP binding and ATPase activity, and integral components of the membrane.

44 First-principles path-integral computations are carried out, providing essenti

45 ol can outperform a traditional proportional integral controller with continuous control, when faced

46 g the physiological ventricular AP and their integrals covary in individual myocytes.

47 -Watson inactivation kinetic model, based on integral CT (ICT) dose, well fitted the inactivation of

48 integral of the PFA concentration over time (integral CT or ICT).

49 en option, in a domain for which conflict is integral: decisions involving risk.

50 source is controlled via a PID (proportional-integral-derivative) controller implemented on a microco

51 ven partial brain irradiation of 10 or 30 Gy integral dose using 100 MeV protons configured either as

52 bout social relationships that we observe is integral during person perception, to better help us int

53 Epithelia are structurally integral elements in the fabric of oral mucosa with sign

54 , these results indicate that astrocytes are integral elements of striatal A1R-mediated LTD.SIGNIFICA

55 ockets, and pores) are prevalent in membrane-integral enzymes, channels, transporters, and receptors,

56 The inputs for the three-dimensional Faddeev integral equation are the off-shell boost two-body t-mat

57 tivistic interactions by solving a nonlinear integral equation using an iterative scheme.

58 at the Hibiscus green spot virus BMB2 MP, an integral ER protein, induces constrictions of ER tubules

59 t a top-heavy above-ground biomass, but this integral feature poses a weight-induced challenge to tru

60 enomenon is a diagnostic signature linked to integral features of dough complexes formed by some whea

61 dispensable for epithelial branching, it is integral for building the tracheal architecture and prom

62 oastal Plain is a GBH where disturbances are integral for ecosystem maintenance.

63 le knowledge of highly structured regions is integral for mechanistic insights into the viral infecti

64 that contributions of the immune system are integral for NMJ reinnervation and functional muscle rec

65 reveal that not only cNav but nNav are also integral for preventing disease-induced failure in human

66 Genome-wide association studies (GWAS) are integral for studying genotype-phenotype relationships a

67 s work, we show how to use the Gauss linking integral (GLN) in the form of a matrix diagram-for a pai

68 .0% in the crushed group versus 32.7% in the integral group (odds ratio, 0.92 [95% CI, 0.65-1.30], P=

69 .9% in the crushed group versus 57.3% in the integral group (odds ratio, 1.11 [95% CI, 0.78-1.58], P=

70 n 0% in the crushed group versus 0.8% in the integral group, and in 0.3% in the crushed group versus

71 0.3% in the crushed group versus 1.1% in the integral group, respectively.

72 ion of incidence and recurrence rates, is of integral importance in cancer immunotherapy to inform ma

73 lammatory response, and they demonstrate the integral importance of SLs in the physiology of P. gingi

74 about the function of the BBSome, a complex integral in ciliary and intracellular trafficking, in ri

75 e approaches and detail how they have become integral in correlative microscopy workflows.

76 Aggregation Database (gnomAD)(4) have become integral in the interpretation of single-nucleotide vari

77 Remarkably, I(Kr) and I(NaL) integrals in each control myocyte were highly correlated

78 est that none of the complexes has a single, integral inner-sphere water that exchanges rapidly on th

79 These mechanisms are integral inputs into fine-tuning the responses to hypoxi

80 s, and tautomer signals are among the common integral interferences that are typically encountered.

81 Key to the tunability is the exchange integral (K(H,L)), which ideally is constant throughout

82 se overflow waters of the Nordic Seas are an integral link and important diagnostic for the stability

83 an, and prasugrel, administered as chewed or integral loading dose, on IPA in patients undergoing pri

84 The (13)C-satellite signals of adjacent integrals, low-level impurities, and tautomer signals ar

85 populations, cell-surface proteins are often integral markers of cellular function and serve as prima

86 ota, stimulated by secreted coumarins, is an integral mediator of plant adaptation to iron-limiting s

87 ty yet conserved interfaces, can function as integral members of large multimolecular assemblies, and

88 membrane drives clustering of retromer-bound integral membrane cargo prior to its packaging into a na

89 o-domain protein consisting of an N-terminal integral membrane domain and a C-terminal extracytoplasm

90 ses involved in lipid synthesis, such as the integral membrane enzyme diacylglycerol acyltransferase

91 an steroid 5alpha-reductase 2 (SRD5A2) is an integral membrane enzyme in steroid metabolism and catal

92 entapeptide translocase (MraY), an essential integral membrane enzyme that catalyzes the first commit

93 which is catalyzed by a family of eukaryotic integral membrane enzymes known as DHHC protein acyltran

94 Eukaryotic PLMTs are integral membrane enzymes located in the endoplasmic ret

95 llenges of predicting structural features of integral membrane enzymes.

96 min K epoxide reductases (VKOR), a family of integral membrane enzymes.

97 nal design of pharmaceutical drugs targeting integral membrane G protein-coupled receptors (GPCR) req

98 The integral membrane M2 protein is a 97-residue membrane pr

99 transcription factor that, together with its integral membrane periplasmic binding partner ToxS, is c

100 the assembly factor vacuolar ATPase assembly integral membrane protein (VMA21), whose X-linked mutati

101 We then apply the strategy to an integral membrane protein by comparing the shapes of a p

102 The integral membrane protein Lit (lipoprotein intramolecula

103 ontext for localizations of SpmX, a low-copy integral membrane protein sequestered by PopZ as part of

104 The human integral membrane protein SERINC5 potently restricts HIV

105 terior reaction chamber" is unprecedented in integral membrane protein structures.

106 ial antigen of the prostate 1 (STEAP1) is an integral membrane protein that is highly up-regulated on

107 and lymphocyte protein (MAL) is a tetraspan integral membrane protein that resides in detergent-inso

108 , TaiP prevents ATG16L1 interaction with the integral membrane protein TMEM59 and allows the reroutin

109 Synaptotagmin 1 (Syt1) is an integral membrane protein whose phospholipid-binding tan

110 Ste24, an integral membrane protein zinc metalloprotease, is found

111 we report a strong rheostat position in the integral membrane protein, Na(+)/taurocholate (TCA) cotr

112 ide-ranging effects on the phenotype of this integral membrane protein.

113 ain important low-resolution information for integral membrane proteins (IMPs), challenging targets f

114 Translocation of secretory and integral membrane proteins across or into the ER membran

115 f membrane insertion for numerous eukaryotic integral membrane proteins and tail-anchored proteins.

116 Integral membrane proteins are encoded by approximately

117 Integral membrane proteins are exposed to a complex and

118 Alpha-helical integral membrane proteins contain conserved sequence mo

119 mer orchestrates the selection and export of integral membrane proteins from the endosome via retrogr

120 Sorting of integral membrane proteins from the trans-Golgi network

121 The internal motions of integral membrane proteins have largely eluded comprehen

122 transmembrane helix (TMH) of many multi-pass integral membrane proteins into the ER membrane, and it

123 receptors (GPCRs) comprise a large class of integral membrane proteins involved in the regulation of

124 The latter contains integral membrane proteins of three sizes, collectively

125 pled receptors (GPCRs) are a large family of integral membrane proteins responsible for cellular sign

126 proximately 25% of eukaryotic genes code for integral membrane proteins that are assembled at the end

127 encoding these proteins is controlled by two integral membrane proteins, BlaR1 and MecR1, which both

128 the identification of 188 and 124 endogenous integral membrane proteins, respectively, some with as m

129 n Azo-aided bottom-up method for analysis of integral membrane proteins, which are key drug targets a

130 However, lipidated polypeptides and integral membrane proteins-an important class of biomole

131 luding the correct folding and expression of integral membrane proteins.

132 ns are a key element of the function of many integral membrane proteins.

133 act as solvents and functional cofactors for integral membrane proteins.

134 They define the largest family of integral membrane receptors at the surface of the cells

135 They consist of an integral membrane S-component (that binds substrate) and

136 cal structural insights into the function of integral membrane steroid reductases and may facilitate

137 d inhibition for SRD5A2 and other eukaryotic integral membrane steroid reductases remain elusive due

138 inities (low nanomolar to millimolar) for an integral membrane transport protein in both detergent-so

139 Integral membrane transporters can present a challenging

140 (1) subcomplexes and assists reassembly with integral membrane V(o) complexes.

141 our data define cholesterol metabolism as an integral metabolic pathway for the optimal functioning o

142 ate 1:1 subrandomization to chewed (n=21) or integral (n=21) tablets administration.

143 pe III interference accumulated deletions of integral number of codons in an essential gene and much

144 ients affected by FSHD carry deletions of an integral number of tandem 3.3 kilobase repeats, termed D

145 ation in water bodies, DGT provided a better integral of loadings and exposure than grab sampling.

146 by the absence of increase in velocity-time integral of the left ventricular outflow tract greater t

147 riod commands retain their dependence on the integral of the move period commands.

148 exposure of microorganisms to PFA, i.e., the integral of the PFA concentration over time (integral CT

149 The band-limited integral of the transmission coefficient averaged for bo

150 ocal contributions utilizing the Biot-Savart integral of vorticity in a sphere of radius R.

151 eV, large intermolecular electronic coupling integrals of 12.1-37.9 meV rationalizing the 3D electron

152 s out the foundation for cryo-EM analysis of integral or peripheral MPs whose functions are affected

153 e challenging as they involve Brillouin zone integrals over two crystal momenta and depend critically

154 Endothelial cells are an integral part in lung fibrosis.

155 e cooperation of Multiplexin and Eater as an integral part of a homing mechanism that specifies and m

156 e lifestyle and risk factor management as an integral part of AF management may help in the preventio

157 Force exertion is an integral part of cellular behavior.

158 One-carbon metabolism (OCM), an integral part of cellular intermediary metabolism, produ

159 Perisynaptic astrocytic processes are an integral part of central nervous system synapses(1,2); h

160 Visual speech carried by lip movements is an integral part of communication.

161 Lymphatic vasculature is an integral part of digestive, immune and circulatory syste

162 ine-communication applications has become an integral part of everyday life, some individuals suffer

163 h (pyroptosis, apoptosis, necroptosis) is an integral part of host defense against pathogens.

164 nature of society, shift work has become an integral part of many industries.

165 Milk oxidases are an integral part of milk immune system, and good indicators

166 communicating with providers online) are an integral part of modern healthcare delivery.

167 ents to sub-physiological temperatures is an integral part of modern medicine.

168 Energy storage is an integral part of modern society.

169 deployable viral genome sequencing can be an integral part of outbreak response and epidemiological i

170 Sexual health is an integral part of overall health in older age.

171 communities, suggesting that wildfire is an integral part of peatland ecology rather than an anomaly

172 Cell fate maintenance is an integral part of plant cell differentiation and the prod

173 The chloroplast genome is an integral part of plant genomes in a species along with n

174 eds to be brought close to communities as an integral part of primary health care to reach more peopl

175 Interdisciplinarity is an integral part of Prof. Stupp's research philosophy, and,

176 oordinated water molecules are frequently an integral part of protein-protein and protein-ligand inte

177 Empathy is an integral part of socioemotional well-being, but recent r

178 Simulation has become integral part of surgical training but there are a numbe

179 Neurofilaments light chain (Nf-L), an integral part of the axonal structure, has emerged as a

180 now becomes clear that cell metabolism is an integral part of the complex landscape of regulatory mec

181 not surprising that our community is now an integral part of the current renaissance in metabolic re

182 of G-protein signaling (RGS) proteins are an integral part of the G-protein networks; however, these

183 l, as well as within subgroups, served as an integral part of the guideline development.

184 k base pair with a uridine, thus becoming an integral part of the helical structure.

185 ansyl chromophore which functions as both an integral part of the ligand and a fluorescent reporter.

186 Big Data will be an integral part of the next generation of technological de

187 Latency is an integral part of the pathogenic strategies of microbes t

188 s must be captured and shared publicly as an integral part of the scientific process.

189 l prefrontal hand-related areas and thus are integral part of the so-called "lateral grasping network

190 cate that geosmin and 2-MIB production is an integral part of the sporulation process, completing the

191 he PIMT-mediated protein repair system is an integral part of the stress-tolerance mechanism in plant

192 coccus xanthus and form a complex that is an integral part of the T4aPM.

193 Autophagy, an integral part of the waste recycling process, plays an i

194 a delay of acute starvation, rather than an integral part of thymineless death.

195 ty datasets, machine learning is becoming an integral part of understanding and engineering living sy

196 However, telehealth will continue to be an integral part of urology after the pandemic and our fiel

197 metallo-borospherenes, where metal atoms are integral parts of the cage surface.

198 ting evidence that astrocytes are active and integral players in synaptic communication, and that neu

199 sons), which did not provide higher IPA over integral prasugrel (6.3+/-11.4; P=0.47), despite yieldin

200 riority of chewed prasugrel as compared with integral prasugrel, each with alpha=0.016 for the primar

201 centration but not greater IPA compared with integral prasugrel.

202 etween parental chromosomes in meiosis is an integral process for the creation of gametes.

203 These data were used to parameterise integral projection models quantifying the effect of the

204 When we incorporate this asymmetry into integral projection models, the predicted size structure

205 , known as microglia, and their receptors as integral regulators of both the initiation and propagati

206 hondrial inter-organelle communication is an integral regulatory component of functional MOMP executi

207 Our study uncovers MaIL1 as an integral RNA component of the TLR4-TRIF pathway and pred

208 nt a theoretical model that demonstrates the integral role chromosome organization and structural mec

209 Our data highlight an integral role for CaMKII in neuronal TRPV4-associated Ca

210 Here, we demonstrate an integral role for H1 linker histones in silencing repeti

211 Their integral role in coordinating metabolism has led to thei

212 Peter Medawar played an integral role in developing the concepts of immunologic

213 Hedonic processing plays an integral role in directing appropriate behavior, but dis

214 D51-associated protein 1 (RAD51AP1) plays an integral role in homologous recombination by activating

215 Communication plays an integral role in human social dynamics and is impaired i

216 Our data suggest that primary cilia play an integral role in maintaining the function of PCs in the

217 e ubiquitin proteasome system (UPS), have an integral role in maintaining this balance.

218 light how mitochondrial activity may play an integral role in modulating PVI-mediated cognitive proce

219 is clear that the lymphatic system plays an integral role in physiology, and in pathological setting

220 ein architecture of the kinetochore plays an integral role in specifying the mechanisms underlying it

221 where the cellular polarity program plays an integral role in the ability of IECs to partially tolera

222 Occupational therapists have an integral role in the multidisciplinary management of peo

223 se results suggest that expectations play an integral role in the neural computations underlying perc

224 nsory processing at early stages, playing an integral role in the perceptual process.

225 x (ECM) that is rich in hyaluronan, plays an integral role in this immune evasion.

226 s and cell proliferation, consistent with an integral role of BMP9 in vessel maturation.

227 Due to the integral role of OGG1 in maintaining cellular homeostasi

228 These results support integral roles for PFC astrocytes in the behavioral acti

229 monstrated that bacterial K(+) channels have integral roles in electrical signaling, information prop

230 tors, and signaling molecules appear to play integral roles in protective immunity to liver-stage mal

231 TRIM family proteins play integral roles in the innate immune response to virus in

232 lusters, where the templating anion plays an integral structure-defining role.

233 patients were assigned to either crushed or integral tablets of prasugrel loading dose.

234 ading dose of prasugrel either as crushed or integral tablets.

235 dies suggest that proinsulin is an early and integral target autoantigen in T1D.

236 These relations led us to propose an integral-threshold model in which the cell cycle is cont

237 idic Type I Signal Peptidase 1 (Plsp1) is an integral thylakoid membrane signal peptidase that requir

238 tronic health record (EHR) provider notes is integral to advancing precision medicine.

239 transformations are of utmost importance and integral to advancing this area of synthesis.

240 interferon-stimulated genes [ISGs]) that are integral to antiviral host defense.

241 Protein dynamics are integral to biological function, yet few techniques are

242 Ectomycorrhizal (ECM) fungi are integral to boreal and temperate forest ecosystem functi

243 Integral to cancer staging is "metastasis," defined as t

244 In mammalian systems, uridylation is integral to cell cycle control of histone mRNA levels.

245 scriptional regulator of chaperones(1,2), is integral to cell-fate decisions underlying survival or d

246 Mechanical forces are integral to cellular migration, differentiation and tiss

247 ydrolases (GH45) are endoglucanases that are integral to cellulolytic secretomes, and their ability t

248 em enables capture and analysis of molecules integral to chemical communication that would otherwise

249 Navigating conflict is integral to decision-making, serving a central role both

250 Clustering patient omic data is integral to developing precision medicine because it all

251 Mechanical forces are integral to development-from the earliest stages of embr

252 hiral environment of the phosphate anion are integral to enantiocontrol in the transition state.

253 nterplay between GluN and mGluR5 pathways as integral to glutamatergic dysregulation and suggest prot

254 st2, encodes a carbohydrate sulfotransferase integral to glycosaminoglycan sulfation.

255 or more commonly red blood cells (RBCs), is integral to health care systems worldwide but requires c

256 Intrinsic complement C3 activity is integral to human T helper type 1 (Th1) and cytotoxic T

257 It is, therefore, integral to identify patients who may benefit from biven

258 rasutterella excrementihominis appears to be integral to inflammatory and metabolic dysregulation dur

259 The inflammasome is integral to innate immune responses but over-activation

260 Cardiovascular regulation is integral to life.

261 by all three factors are enriched for genes integral to mammary gland development as well as epithel

262 Magnetic proximity effects are integral to manipulating spintronic(1,2), superconductin

263 ntified influence of a process that has been integral to many TBMs for decades, highlighting the valu

264 ng in living cells have advanced and are now integral to medicinal chemistry workflows.

265 nse by ~30%, indicating that nitric oxide is integral to neurovascular coupling in humans.

266 Nitric oxide signalling is integral to NVC in humans, providing a new direction for

267 regation may be a common amyloid feature and integral to pathology.

268 The EHR has become integral to perioperative care.

269 Compassion is integral to professional nursing practice worldwide and

270 Medicaid is integral to public health because it insures one in five

271 ally in susceptible populations, nicotine is integral to risk of health effects, but overall e-cigare

272 HGSOC cell lines demonstrated that MRCKA was integral to signaling that regulated the cell cycle chec

273 se results indicate that the CCT2 subunit is integral to the activity of the chaperonin and is needed

274 expose regulation of global RNAPII levels as integral to the cellular DNA-damage response and open th

275 ), (ii) use of anomalous scattering elements integral to the crystallization buffer (extrinsic cobalt

276 S) is of global importance and within Europe integral to the EU IAS regulation.

277 Schwann cells (SCs) are integral to the formation and function of the peripheral

278 factor B (FB) is a key node in the AP and is integral to the formation of C3 and C5 convertase.

279 arbor diverse microbial communities that are integral to the functioning of the host.

280 olecular motors of the ATP synthase class is integral to the metabolism of cells.

281 nt receptor potential 3 (TRPC3) channels are integral to the propagation of seizures in SE, and vascu

282 Activity-dependent gene expression is integral to the synaptic plasticity underlying learning

283 transition and that nucleolar recruitment is integral to their mechanism of action.

284 Integral to their success is the infused lubricant layer

285 Integral to these processes is the tip-link protein comp

286 Ribs and vertebrae are integral to this locomotor mode, but 3D motion of the ax

287 concentrations of adenosine nucleotides are integral to this regulation, with ATP and ADP closing th

288 ow data donation, and subsequent sharing, is integral to this.

289 vlPAG) and neighboring dorsal raphe (DR) are integral to threat prediction, and are responsive to acu

290 ith decreased mRNA encoding Dgat2, an enzyme integral to triglyceride synthesis.

291 se hubs have prognostic value and are likely integral to tumor metabolism and breast cancer.

292 Host cell factors are integral to viral replication.

293 etween the two genotypes revealed higher and integral tolerance in C-76 through activation of key gen

294 tein from influenza A virus is a tetrameric, integral transmembrane (TM) protein that plays a vital r

295 bedding shell and the occluded Asp act as an integral until which minimally rearranges even as the bu

296 constituents was evaluated, looking for the integral valorization of this resource towards the zero-

297 or SARS-CoV-2 viruses and thus increases the integral viral load.

298 Aortic ejection time(AET) and velocity time integral(VTI) were increased, and (4) Aortic acceleratio

299 Velocity-time integral was measured by transthoracic echocardiography.

300 Central venous pressure and velocity-time integral were measured before and during passive leg rai