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1 iV-1) and the other (AurliV-2) a chromosomal integrant.
2 arent; the other parent does not contain the integrant.
3 printed lines had a single 15.7-kb transgene integrant.
4 panned four orders of magnitude among clonal integrants.
5 els is increased 86-fold within +/-150 kb of integrants.
6 levels is increased 86-fold within 150 kb of integrants.
7 onal envelope proteins are supplied from HBV integrants.
8 rces and can be stably maintained as genomic integrants.
9 n sites was developed and used to clone 1029 integrants.
10 cB gene that allows for the resolution of co-integrants.
11  no influence on promoter activity in stable integrants.
12 sgene rearrangement in single-copy transgene integrants.
13 RNA gene, permitting biological selection of integrants.
14 ndomized position in sequenced concerted DNA integrants, although in some instances there were prefer
15 s method relied on in vivo selection of rAAV integrants and could be employed for the liver but not f
16 owever, the relationship between initial RIG integrants and how these evolve in patients over time ar
17 eramplification is enriched 16-fold near HPV integrants, and the extent of focal host genomic instabi
18                                        These integrants appear to be maintained by cellular prolifera
19                     Transcriptionally active integrants are characterized by unmethylated regions in
20                               Moreover, many integrants are defective, and new studies are required t
21 king it sometimes difficult to discern which integrants are exogenous and likely more clinically rele
22                                   Individual integrants are isolated from bacteria containing drug-re
23                      High yields of targeted integrants are obtained, even in a recA background.
24 anded breaks (DSB) but the resulting nuclear integrants are often immediately unstable.
25                                              Integrants are selected as antibiotic-resistant transfor
26                       Following integration, integrants are stably maintained in the absence of antib
27  L. monocytogenes, forms stable, single-copy integrants at a frequency of approximately 10(-4) per do
28 modest effect on expression of some proviral integrants at late times post-transduction.
29  which can be used as a marker for selecting integrants at mutant ade2 loci commonly present in labor
30                            The markedly more integrant BBB in neonatal brain than in adult brain afte
31 SV and TVCV, one of the parents contains the integrant but is has not been seen to be activated in th
32 lines, Hep3B and PLC/PRF/5, that contain HBV integrants but do not produce HBV virions and have no si
33 or contains the KanMX selectable marker, and integrants can be selected by resistance to G418.
34 or contains the hisG-URA3-hisG cassette, and integrants can be selected by uracil prototrophy.
35 s rendering them non-functional, more recent integrants can maintain the capacity for full viral prod
36  integration junctions using high-throughput integrant capture sequencing of infected human cells.
37                                        Using integrant capture sequencing, more than 600,000 AAV-5 in
38      Using a novel high-throughput approach, integrant capture sequencing, nearly 12 million AAV junc
39                                          New integrants carry all structural characteristics typical
40 ne transcription is disrupted via intragenic integrants, chimeric transcription, outlier expression,
41 dy, the expression phenotypes of hundreds of integrant clones were analyzed to identify factors contr
42 Molecular characterization of the mutant ITR integrants confirmed the presence of the trs mutation in
43               Moreover, the number of random integrants decreased by over 54-fold resulting in a 1:3
44     Over time, phenotypic analysis of clonal integrants demonstrated that SB undergoes additional pos
45                   IMPORTANCE The presence of integrant-derived RNAs (id-RNAs) and 5'-human-HBV-3' tra
46 ted HBV DNA, including 5'-HBV-human-3' RNAs (integrant-derived RNAs [id-RNAs]) and 5'-human-HBV-3' tr
47                                              Integrant-derived transcripts showed vast diversity in t
48  is limited to genes within 200 kb of an HPV integrant, dysregulation of the human epigenome in the f
49                                   The double integrant efficiently incorporates 3H-thymidine into nuc
50 ral DNA, we hypothesized we could show these integrants exhibit sequence differences from their exoge
51                All characterized chloroplast integrants exist apart from native mitochondrial genes,
52         Whole-genome sequencing revealed HPV integrants flanking and bridging extensive host genomic
53 h-throughput creation of libraries of random integrants for purposes including gene knock-out librari
54                                      Indeed, integrants for three of the segments were not obtained i
55                                          DNA integrant frequencies were stable over time (<4-fold dif
56 esult in significant reductions in recovered integrants from bacteria, due to increases in one-ended
57                          Among the recovered integrants from reactions with mutated U5 but not U3 IN
58         The viral early gene promoter in one integrant gave rise to an unspliced fusion transcript co
59    Five site-specific adeno-associated virus integrants generated in a model system with an Epstein-B
60             The functional properties of the integrant-generated HBsAgs were examined using two human
61                                         Many integrants have been sequenced, and have all of the hall
62                      Among the site-specific integrants, however, a third experienced gene silencing.
63 tal ADA enzyme activity and ADA activity per integrant in the transduced cells demonstrated that the
64 t is not remobilized producing stable clonal integrants in all daughter cells.
65  The results show the absence of EAV and ALV integrants in DNA prepared from MVVE-inoculated human ce
66 omoter activity induced by culture of stable integrants in high glucose.
67 ands of endogenous retrovirus (ERV) germline integrants in highly divergent, previously unsequenced m
68 Determining the diversity of host genes with integrants in HIV-infected cells that persist for prolon
69 ent methods, we were unable to identify rAAV integrants in mouse muscle.
70 ite analysis revealed common proviral vector integrants in NOD/SCID repopulating cells and in the bab
71 rge pool of individually barcoded lentiviral integrants in the presence and absence of a perturbation
72  of DSB formation in a single-copy minilocus integrant indicates that efficient DSB formation at the
73                         The structure of the integrants is complex, and it is thought that episomal v
74                                         Each integrant line chosen for analysis harbors a single copy
75                                The number of integrant loci is low for BSV and PVCV and high in TVCV.
76 We present a model of "looping" by which HPV integrant-mediated DNA replication and recombination may
77 by mouse mammary tumor virus (MMTV) proviral integrant Mtv-1, we have analyzed these regions in T cel
78 eletion of chromosomal DNA, and another DHBV integrant occurred in a telomeric repeat sequence.
79     In five lines of mice carrying multicopy integrants of constructs that either lacked Edelta or ca
80 tains a significant amount of NUMTs (nuclear integrants of mitochondrial DNA) and NUPTs (nuclear inte
81 nts of mitochondrial DNA) and NUPTs (nuclear integrants of plastid DNA) that are continuously acquire
82               Resulting targeted single-copy integrants of the p53-CAT reporter show strong genotoxic
83                                              Integrants of three pararetroviruses, Banana streak viru
84 omoter, allowing identification of potential integrants on the basis of phenotype.
85      HIV-1 provirus, either as a chromosomal integrant or as an episomal plasmid in HeLa cells, forms
86 expressed in R. rubrum either as single-copy integrants or on multiple-copy plasmids, these variants
87  with gene-trap virus produced from a single-integrant packaging cell line that allowed us to quantit
88  Germinal center (GC) formation, which is an integrant part of humoral immunity, involves energy-cons
89 s maintained a relatively constant HIV-1 DNA integrant pool that was genetically stable during long-t
90                                Both of these integrants provide further evidence that concerted integ
91  underpin clonal selection of one particular integrant remain poorly understood.
92 tion of the products is consistent with most integrants representing a concerted integration in which
93  expanses of the genome, irrespective of the integrant's transcriptional status.
94 id was random except that the orientation of integrants selected was apparently influenced by supF tr
95                                      Plasmid integrants selected with mevinolin were resolved with 5-
96                                   All of the integrants sequenced were inserted into different sites
97                            In 2 of 14 mutant integrants sequenced, deoxynucleotides were deleted from
98                      In a striking number of integrants, short identical sequences were shared betwee
99        Sequence analyses of individual HIV-1 integrants showed loss of 2 bp from the ends of the dono
100      An analysis of numerous clonal proviral integrants showed that mutation of CpGs in both clusters
101 he target cassette, we were able to identify integrants simply by the loss of mini-white eye color.
102                           Subsequently, this integrant strain is transformed with a plasmid expressin
103 extant Tf2, and silence and immobilize a Tf1 integrant that becomes sequestered into Tf bodies.
104 of CpGs in both clusters eliminated proviral integrants that were completely silenced.
105 iently increased promoter activity in stable integrants, the increase was not sustained (6 h).
106                       There are two forms of integrant, those that can form episomal viral infections
107 ed study of the biogenesis and properties of integrant-transcribed 5'-human-HBV-3' and 5'-HBV-human-3
108 uable model systems for detailed analysis of integrant-transcribed HBV RNAs, spliced HBV RNAs, and me
109 h HBV contained both replication-derived and integrant-transcribed HBV RNAs.
110     However, our knowledge of the cccDNA and integrant transcriptomes is confounded by overlapping vi
111                                     One DHBV integrant was associated with a small deletion of chromo
112                                          The integrant was unable to process the trnD transcript at t
113     GFP expression from transposase-mediated integrants was Mendelian through the eighth generation.
114 gration sites, and GFP expression from these integrants was stable over time.
115 alactosidase expression of a pyr-lacZ fusion-integrant were isolated as blue colonies on X-Gal (5-bro
116  truncated L1s, as over 52% (27/51) of total integrants were <1/3 the length of a full-length element
117 ntegrated AAV indicated that essentially all integrants were AAVS1 site specific.
118  several positions randomized, the concerted integrants were examined for statistically significant r
119                            Forty-two de novo integrants were recovered that faithfully mimic many asp
120 onjugal transfer into P. aeruginosa, plasmid integrants were selected, and deletion of unwanted DNA s
121  cellular DNA segments that flanked proviral integrants were sequenced to confirm identity.
122 s well as individual clones harboring single integrants--were analyzed for reporter expression during
123 onstruct targeting DNMT1 and isolated stable integrants with different levels of protein.
124 differential promoter activity in cccDNA and integrants, with implications for the efficacy of epigen
125 s the first detailed analysis of baculovirus integrants within mammalian cells.
126                                 In contrast, integrants without evidence of expression lack consisten
127  Mu; target-primed replication of the linear integrant would subsequently break the chromosome.
128                      One of the seven intein integrants yielded I-TevI of high activity.

 
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