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1 t cell migration on fibronectin requires the integrin alpha5beta1.
2 re regulated by adhesion proteins, including integrin alpha5beta1.
3 man Fn, and the epithelial cell Fn receptor, integrin alpha5beta1.
4 as a molecular bridge between M1 protein and integrin alpha5beta1.
5  by antibodies to the endogenously expressed integrin alpha5beta1.
6 as labeled by antibodies to the RGDS-binding integrin alpha5beta1.
7 h follow ligation of Fn to its receptor, the integrin alpha5beta1.
8 orming a liquid-liquid phase separation with integrin alpha5beta1.
9 rolled by fibronectin (FN) and its receptor, integrin alpha5beta1.
10 sion to fibronectin, the canonical ligand of integrin alpha5beta1.
11 reas it cooperates with talin for activating integrin alpha5beta1.
12  recently in haptotaxis via interaction with integrin alpha5beta1.
13  Fibronectin (FN) depends on the FN receptor Integrin alpha5beta1.
14 eir survival to fibronectin by up-regulating integrin alpha5beta1.
15 (68)Ga-aquibeprin shows high selectivity for integrin alpha5beta1 (50% inhibition concentration [IC50
16 conjugated to a cyclic peptide that binds to integrin alpha5beta1, a factor that promotes osteogenesi
17                               Antagonists of integrin alpha5beta1 activate PKA, which then leads to t
18 slocation of YAP in ECs that is dependent on integrin alpha5beta1 activation.
19 ion and metastasis through direct binding to integrin alpha5beta1, alphavbeta1, and epidermal growth
20 he related integrin alphavbeta8, but not the integrins alpha5beta1, alphavbeta3, alphavbeta5 and alph
21 ed PEAK1 as an interactor of the RGD-binding integrins alpha5beta1, alphaVbeta3, and alphaVbeta5 in f
22 70C) markedly inhibited adhesion mediated by integrins alpha5beta1, alphavbeta5, and alphavbeta6, par
23  that M4 increases expression of "migratory" integrins alpha5beta1, alphaVbeta5, and alphaVbeta6, whe
24  an antibody against the fibronectin-binding integrin alpha5beta1 also blocked the p70S6K phosphoryla
25                                              Integrin alpha5beta1 and alphavbeta3 affinities were det
26                     We show that endothelial integrin alpha5beta1 and alphavbeta3 interactions with f
27 erm control and FGR pregnancies, we assessed integrin alpha5beta1 and alphavbeta3 regulation during c
28                                GT1b binds to integrin alpha5beta1 and blocks the integrin-fibronectin
29 oprecipitation, while direct binding between integrin alpha5beta1 and CCN2 was confirmed in cell-free
30                                              Integrin alpha5beta1 and CD40 simultaneously bind to CD4
31             Previously, we demonstrated that integrin alpha5beta1 and Fn1 (fibronectin) expressed in
32           Cell-ECM interactions regulated by integrin alpha5beta1 and Fn1 play essential roles at eac
33  to investigate cellular mechanisms by which integrin alpha5beta1 and Fn1 regulate aortic arch artery
34 CCN2 regulates PSC function via cell surface integrin alpha5beta1 and heparan sulfate proteoglycan re
35 to galectin-3, blocking its interaction with integrin alpha5beta1 and impairing angiogenesis.
36  D3 coordinately regulates the expression of integrin alpha5beta1 and integrin alphavbeta3 during ang
37            Evidence is now provided that the integrin alpha5beta1 and its ligand fibronectin are coor
38  serves as a mechanism for the activation of integrin alpha5beta1 and the atherogenic phenotype of EC
39 tect and differentiate between two different integrins (alpha5beta1 and alphavbeta3) bound to RGD-con
40            CHO cells express two RGD-binding integrins (alpha5beta1 and alphavbeta5) that, although n
41       Affinity chromatography identified the integrins alpha5beta1 and alpha(v)beta3 as surface recep
42                      The fibronectin binding integrins alpha5beta1 and alpha4beta1 generate signals p
43                                              Integrins alpha5beta1 and alphavbeta3 also localized to
44 e recommendable for complementary mapping of integrins alpha5beta1 and alphavbeta3 by PET, allowing f
45  xenografts (human melanoma, expressing both integrins alpha5beta1 and alphavbeta3) were used.
46 itional evidence of "cross-talk" between the integrins alpha5beta1 and alphavbeta3, and support the i
47     Alternatively spliced forms of CD97 bind integrins alpha5beta1 and alphavbeta3, decay acceleratin
48 are tracers for selective in vivo mapping of integrins alpha5beta1 and alphavbeta3, respectively, by
49 t adhesion response to selective ligands for integrins alpha5beta1 and alphavbeta3, which are both re
50 ich high activity toward fibronectin binding integrins alpha5beta1 and alphavbeta6 and not on vitrone
51 bronectin, whereas other fibronectin-binding integrins, alpha5beta1 and alphaVbeta3, were resident at
52 (via integrin alpha2beta1), fibronectin (via integrin alpha5beta1), and fibrinogen (via integrin alph
53 and angiogenesis via binding to its receptor integrin alpha5beta1, and enhances downstream focal adhe
54 independent manner by complexing with active integrin alpha5beta1, and mediating beta-arrestin2-depen
55                          JSM6427, a specific integrin alpha5beta1 antagonist, significantly inhibited
56         As Hox D3, integrin alphavbeta3, and integrin alpha5beta1 are expressed on tumor blood vessel
57          Fibronectin and its major receptor, integrin alpha5beta1 are required for embryogenesis.
58                            Here, we identify integrin alpha5beta1 as the endothelial cell-surface bin
59                      These findings identify integrin alpha5beta1 as the molecular target of Vi media
60             Notably, the HGR motif activates integrin alpha5beta1, as reflected by an increase in end
61                  P4G11 induces clustering of integrin alpha5beta1 at lateral, intercellular surfaces.
62 vity of FN was mediated by the activation of integrin alpha5beta1 at Tensin1-positive fibrillar adhes
63 tion of fibronectin and acute disruptions of integrin alpha5beta1 binding to fibronectin increases th
64                            In the absence of integrin alpha5beta1 binding to fibronectin, convergence
65                                              Integrin alpha5beta1 binds to an Arg-Gly-Asp (RGD) motif
66                  These findings suggest that integrin alpha5beta1 binds to monomeric CD40L through th
67 peptide, and novel nonpeptide antagonists of integrin alpha5beta1 blocked angiogenesis induced by sev
68 Cs blunted the anti-atheroprone effect of an integrin alpha5beta1-blocking peptide (ATN161) in Apoe-/
69  that cyclic forces applied to a fibronectin-integrin alpha5beta1 bond switch the bond from a short-l
70 al reinforcement strengthens the fibronectin-integrin alpha5beta1 bond through the RGD binding site o
71  recruitment of paxillin to sites of lateral integrin alpha5beta1 clustering and is followed by tight
72 structure of the ligand-binding headpiece of integrin alpha5beta1 complexed with fragments of its phy
73  and monoclonal antibody reporters, to image integrin alpha5beta1 conformation.
74                              CCN2 stimulated integrin alpha5beta1-dependent adhesion, migration, and
75 lantoic membrane enhanced angiogenesis in an integrin alpha5beta1-dependent manner.
76              Zyxin silencing led to elevated integrin alpha5beta1-dependent single cell motility.
77  An analysis of HUASMC fibronectin receptor (integrin alpha5beta1) distribution revealed that III1-C
78        Our studies indicate that ligation of integrin alpha5beta1 during angiogenesis suppresses an a
79 -stain electron microscopy, we show that the integrin alpha5beta1 ectodomain adopts extended-closed a
80 nals in an NC cell-autonomous manner through integrin alpha5beta1 expressed by the NC, leading to act
81                                              Integrin alpha5beta1 expression by FACS and Western blot
82        Subsequent analysis revealed elevated integrin alpha5beta1 expression on tumor-infiltrating mo
83           By regulating cell-cell junctions, integrin alpha5beta1 expression, and cell-extracellular
84 d agrees with the experimental CMR effect of integrin alpha5beta1-fibronectin interaction.
85 tween the ECM component fibronectin (fn) and integrin alpha5beta1 forms a complex with ZO-1 in cells
86                                          The integrin alpha5beta1 has been previously implicated in t
87 show that the three conformational states of integrin alpha5beta1 have discrete free energies and def
88                   To investigate the role of integrin alpha5beta1 in cardiovascular development, we u
89 determine the expression and localization of integrin alpha5beta1 in human retinal pigment epithelium
90  remodeling stem from the role of mesodermal integrin alpha5beta1 in neural crest proliferation and d
91 ate proteoglycans functioned as a partner of integrin alpha5beta1 in regulating adhesion of PSCs to C
92             Thus we propose a novel role for integrin alpha5beta1 in regulating epithelial morphogene
93  demonstrate a requisite role for mesodermal integrin alpha5beta1 in signaling between the mesoderm a
94                                Activation of integrin alpha5beta1 induced tyrosine, but not serine, p
95 s showed that c-Abl inhibitor attenuated the integrin alpha5beta1-induced YAP tyrosine phosphorylatio
96 ted against the epithelial cell Fn receptor, integrin alpha5beta1, inhibited Fn and FBS-mediated inva
97  by soluble endoglin, RGD peptides, the anti-integrin alpha5beta1 inhibitory antibody LIA1/2 and the
98  The complex of GM3 with tetraspanin CD9 and integrin alpha5beta1 inhibits motility and invasiveness.
99 study clarifies the binding of galectin-3 to integrin alpha5beta1, instead of advanced glycation end-
100 ix proteins such as FN and the corresponding integrins, alpha5beta1 integrin in particular.
101 nment along AC processes, suggesting that FN-integrin alpha5beta1 interaction is involved in filopodi
102                                       Strong integrin alpha5beta1 interactions with CD97 have been id
103                    Here, we demonstrate that integrin alpha5beta1 interacts directly with Cx43 and th
104                                              Integrin alpha5beta1 is among the proteins overexpressed
105                                              Integrin alpha5beta1 is essential for vascular developme
106  the basis of our results, we suggested that integrin alpha5beta1 is involved in BK-induced signaling
107       These data indicate that a signal from integrin alpha5beta1 is necessary for integrin alphavbet
108                                              Integrin alpha5beta1 is overexpressed in tumor-associate
109                                              Integrin alpha5beta1 is poorly expressed on normal quies
110                                              Integrin alpha5beta1 is the first high-affinity cellular
111 r epithelial and A549 cells, suggesting that integrin alpha5beta1 is the major Fn receptor expressed
112                       Our findings show that integrin alpha5beta1 is upregulated in CD11b+Ly6Chi mono
113 e that a major cell surface receptor for FN, integrin alpha5beta1, is also required for the developme
114  stress-induced conformational activation of integrin alpha5beta1 leading to the opening of the HC.
115 gnetic beads or conformational activation of integrin alpha5beta1 leads to the opening of the Cx43 HC
116 eted cells displayed significantly increased integrin alpha5beta1 levels, accompanied by enhanced adh
117             To determine the requirement for integrin alpha5beta1 ligation in order for integrin alph
118                        Thus, fibronectin and integrin alpha5beta1, like integrin alphavbeta3, contrib
119 metry modulates cell shape, adhesion through integrin alpha5beta1, MAPK and STAT activity, and initia
120 aining peptide or antibodies recognizing the integrin alpha5beta1 markedly reduced invasion, suggesti
121 ata indicate that insulin potently activates integrin alpha5beta1 mediated CHO-T cell adhesion, while
122                                          The integrin alpha5beta1 mediated the effects of FN because
123                                              Integrin alpha5beta1 mediates cell adhesion to the extra
124 gatus CalA is an invasin that interacts with integrin alpha5beta1 on host cells, induces endocytosis
125 uces endocytosis in part by interacting with integrin alpha5beta1 on host cells.
126                      Conditional ablation of integrin alpha5beta1 or Fn1 in the Isl1 lineages showed
127 on of this fibronectin-containing matrix via integrins alpha5beta1 or alphaVbeta3 can transfer stress
128                 Major contribution of FnbpAB-integrin alpha5beta1 pathway to internalization was conf
129                      One of these receptors, integrin alpha5beta1, plays a critical role in tumor- an
130                Likewise, an antibody against integrin alpha5beta1 prevented the antiangiogenic activi
131                                              Integrin alpha5beta1 production by PSCs was verified by
132                        Here we show that the integrin alpha5beta1 promotes endothelial cell survival
133 harmacological inhibition of the endothelial integrin alpha5beta1 recapitulated adipocyte-specific An
134 s study indicates that FN, by binding to the integrin alpha5beta1 receptor, stimulates the expression
135 ion of III13 and III7-11 (which contains the integrin alpha5beta1 recognition site), either as a sing
136          In this report, we demonstrate that integrin alpha5beta1 serves as an alternative coreceptor
137    Here, we identify angiopoietin-2 (Angpt2)-integrin alpha5beta1 signaling as an inducer of fat upta
138 ngs demonstrate the critical roles of Angpt2-integrin alpha5beta1 signaling in SAT endothelium in reg
139            Mechanistically, Angpt2 activated integrin alpha5beta1 signaling in the endothelium and tr
140 ha5beta1 mediated CHO-T cell adhesion, while integrin alpha5beta1 signaling in turn enhances insulin
141 ecreased with age, while binding to CD36 and integrin alpha5beta1 significantly increased with age.
142 w molecular weight, nonpeptide antagonist of integrin alpha5beta1, SJ755, can inhibit internalization
143  these established catch-bond formers is the integrin alpha5beta1, the primary receptor for fibronect
144                           TbetaRIII-mediated integrin alpha5beta1 trafficking regulates cell adhesion
145 Purified M1 protein failed to associate with integrin alpha5beta1 unless the integrin had been prebou
146 ndothelial endoglin interacts with leukocyte integrin alpha5beta1 via its RGD motif, and this adhesio
147 ed with enhanced adhesion to fibronectin via integrin alpha5beta1 (VLA-5), but not alpha4beta1 (VLA-4
148                                              Integrin alpha5beta1 was detected in native adult and fe
149                     Binding between CCN2 and integrin alpha5beta1 was determined in cell-free systems
150                                Expression of integrin alpha5beta1 was examined by immunoprecipitation
151 beta1 are cell type specific and differ from integrin alpha5beta1 when the two integrins are coexpres
152 ne expressing a single fibronectin receptor, integrin alpha5beta1, which was uniformly activated with
153 n between VEGF receptor-2 (Flk-1) and the FN integrin, alpha5beta1, which required intact FN because
154 ipitation of matrix metal-loproteinase-9 and integrin alpha5beta1, while endogenous accumulation of G
155 reduced IE binding to the receptors CD36 and integrin alpha5beta1, while hemoglobin AS did not modify
156 he extracellular domain of broadly expressed integrin alpha5beta1 with an affinity comparable to that
157                                  Blockage of integrin alpha5beta1 with ATN161 abolished the phosphory
158             The high affinity interaction of integrin alpha5beta1 with the central cell binding domai

 
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