ライフサイエンスコーパス: integrin beta subunit

1 ectly binding to the cytoplasmic tail of the integrin beta subunit.

2 tensile force takes when applied through the integrin beta-subunit.

3 xY motif within the cytoplasmic tail of most integrin beta subunits.

4 n(s) may be quite distinct from those of the integrin beta subunits.

5 s that act on the short cytoplasmic tails of integrin beta subunits.

6 s that act on the short cytoplasmic tails of integrin beta subunits.

7 r proteins involved in cell adhesion such as integrin beta subunits (all Metazoa).

8 he study point to the similarity between the integrin beta subunits and the MIDAS motif at two of thr

9 in the association of alpha-actinin with the integrin beta subunit, and that PtdIns (3,4,5)-P(3) coul

10 cysteine-rich repeats in the stalk region of integrin beta subunits appear to convey signals impingin

11 Thus, the integrin beta subunits appear to present a MIDAS-like mo

12 Two integrin beta subunits are encoded in the Drosophila gen

13 her antigenic residues in beta2 and in other integrin beta subunits are present on the front.

14 Homologous residues in other integrin beta subunits are similarly critical for ligand

15 mic tail but not with tails from three other integrin beta subunits (beta2, beta3, and beta5) or from

16 el gene product that is highly homologous to integrin beta subunits but lacks associating alpha subun

17 ene and gene product related to those of the integrin beta subunits but whose function(s) may be quit

18 ferent than in beta3 integrins, showing that integrin beta subunits can be specialized to assume diff

19 rupting the C-terminal cytoplasmic domain of integrin beta subunits can have dominant negative effect

20 of the components of CR3 and CR4: the common integrin beta subunit CD18 and the alpha subunits CD11b

21 achieved by targeting the leukocyte beta(2)-integrin beta-subunit CD18 was required to reduce neoint

22 Monoclonal antibodies to beta1 integrins beta-subunit (CD29) also strongly induced tumo

23 Integrin beta subunits contain a highly conserved I-like

24 Integrin beta subunits contain four cysteine-rich repeat

25 The A-domains within integrin beta subunits contain three metal sites termed

26 The ligand-binding head region of integrin beta subunits contains a von Willebrand factor

27 The ligand-binding region of integrin beta subunits contains a von Willebrand factor

28 the extracellular and cytoplasmic domains of integrin beta subunits contribute to these differences.

29 We report an interaction between integrin beta subunit cytoplasmic domain and Rack1, a Tr

30 alin phosphotyrosine-binding (PTB) domain to integrin beta subunit cytoplasmic domains (tails) causes

31 protein, physically associates with certain integrin beta subunit cytoplasmic domains (tails) via it

32 The integrin beta subunit cytoplasmic domains are important

33 Kindlins directly bind integrin beta subunit cytoplasmic domains at a site dist

34 to the sequences in talin that interact with integrin beta subunit cytoplasmic domains.

35 n activation is usually mediated through the integrin beta subunit cytoplasmic tail and can be regula

36 binding of the cytoskeletal protein talin to integrin beta subunit cytoplasmic tails leads to the con

37 The talin FERM F3 subdomain binds both the integrin beta-subunit cytoplasmic domain and PIPK1gamma,

38 n contrast to ligand, talin, which links the integrin beta-subunit cytoplasmic domain to the actin cy

39 ated via the binding of talin and kindlin to integrin beta-subunit cytoplasmic tails.

40 and is dependent on interactions between the integrin beta subunit-cytoplasmic tail and the cytoskele

41 at the SDL is responsible for the defects in integrin beta subunit expression and folding in the abse

42 have determined the genomic structure of an integrin beta-subunit gene from the coral, Acropora mill

43 gnificantly more than have been found in any integrin beta-subunit genes from higher animals.

44 nce of an I domain-like structure within the integrin beta subunit has been proposed based on the sim

45 en shown that a conformational change of the integrin beta-subunit headpiece (i.e. the beta I domain

46 e conformations, it is controversial whether integrin beta subunit I-like domains undergo structurall

47 directional signaling pathways controlled by integrin beta subunits in platelets and describe a high-

48 In this study we identify the domain of the integrin beta subunit involved in determining ligand bin

49 The amino-terminal domain of each integrin beta subunit is hypothesized to contain an ion

50 SCF-derived cells and encodes a novel murine integrin beta subunit-like molecule, dubbed Pactolus-1 (

51 suggest that tyrosine phosphorylation of an integrin beta subunit may be important in initiating out

52 Given the similarity among all integrin beta subunits, our results may help us to under

53 s that potentially reduce interaction of the integrin beta subunit plexin-semaphorin-integrin (PSI) a

54 s on how the inserted (I)-like domain in the integrin beta-subunit regulates ligand binding by the ne

55 of mutants, including swaps among different integrin beta-subunits, show that C1-C2 loop lengths of

56 s small domain is highly divergent among the integrin beta subunits, suggesting that it may play a ro

57 d non-integrin proteins, and possibly in all integrin beta subunits, these two loop segments may repr

58 ntegrin, we fused the cytoplasmic domains of integrin beta subunits to an N-terminal sequence contain

59 e length of this loop may have evolved among integrin beta-subunits to adjust the equilibrium between

60 A wide array of integrin beta subunits was detected in betaTC3 and NIT-1

61 eras of beta3 and beta5, the most homologous integrin beta subunits, were expressed with alphav on th