ライフサイエンスコーパス: integrin receptor

1 through the interaction with the alphavbeta3 integrin receptor.

2 A (FLNa) and inactivation of the alpha5beta1 integrin receptor.

3 interaction between fibrinogen and its Mac-1 integrin receptor.

4 ity to detergent-solubilized alpha(v)beta(3) integrin receptor.

5 n, inhibits angiogenesis via the alpha2beta1-integrin receptor.

6 ns-activation of IGF-IR induced by the beta3 integrin receptor.

7 raction of endorepellin with the alpha2beta1 integrin receptor.

8 lization partially overlaps with the alpha7A integrin receptor.

9 tercellular adhesion molecule-3 grabbing non-integrin receptor.

10 lls attached to laminin-5 through the alpha3 integrin receptor.

11 ted by blocking antibodies against the beta1 integrin receptor.

12 nd lymphangiogenesis via activation of beta1-integrin receptor.

13 l docking sites of the RGD-4C ligand and its integrin receptor.

14 agent that is highly selective for a single integrin receptor.

15 C)-modified quantum dots via the alphavbeta3 integrin receptor.

16 y which signals are propagated in the intact integrin receptor.

17 s but also by inactivating their major beta1 integrin receptors.

18 and density of an immobilized ligand for the integrin receptors.

19 igration in part by interacting with beta(2) integrin receptors.

20 nteractions with alphavbeta3 and alphavbeta5 integrin receptors.

21 M) is facilitated by microvesicle-associated integrin receptors.

22 hance their accessibility to alpha(v)beta(3) integrin receptors.

23 migration through interactions with specific integrin receptors.

24 ind to human cancer cells expressing various integrin receptors.

25 es actin cytoskeleton, adaptor proteins, and integrin receptors.

26 cells, and adhesions formed by cadherin and integrin receptors.

27 and that binds with high affinity to certain integrin receptors.

28 h high affinity and improved selectivity for integrin receptors.

29 ersial, including the regulatory function of integrin receptors.

30 ifferent conformations can utilize different integrin receptors.

31 ed kinase (ILK) is a cytoplasmic effector of integrin receptors.

32 is known to contribute to the activation of integrin receptors.

33 ged by soluble fibrinogen that binds surface integrin receptors.

34 ish its matricellular mode of action through integrin receptors.

35 the RGD and PHSRN bind competitively to the integrin receptors.

36 duce cell migration through interaction with integrin receptors.

37 otein that directly links actin filaments to integrin receptors.

38 esses, which are independent of RGD-mediated integrin receptors.

39 development through beta1-subunit-containing integrin receptors.

40 on, in extracellular matrix proteins, and in integrin receptors.

41 by interactions between FN and cell surface integrin receptors.

42 D-containing peptides, which are ligands for integrin receptors.

43 ronectin and selectively bind to a subset of integrin receptors.

44 sembly of inhibitory nerve terminals through integrin receptors.

45 ng that modulates the signaling threshold of integrin receptors.

46 interaction with alphavbeta6- or alphavbeta8-integrin receptors.

47 trix interaction through various subtypes of integrin receptors.

48 imited by the need for certain RGD-dependent integrin receptors.

49 to alphavbeta3, alphavbeta5, and alpha5beta1 integrin receptors.

50 PB) of endothelial cells upon binding to its integrin receptors.

51 multimeric RGD compounds for alpha(v)beta(3) integrin receptor (ABIR) showed a remarkable increase re

52 t have recently emerged as key regulators of integrin receptor activation and signaling.

53 Comparatively, integrin receptor activation requires TM complex destabi

54 We conclude that LMN binding to beta(1)-integrin receptors acts via FAK/PI-(3)K/Akt to inhibit a

55 s clotting function, but lacks the leukocyte integrin receptor alpha(M)beta(2) binding motif (Fibgamm

56 nteraction of the protein with the leukocyte integrin receptor, alpha(M)beta(2).

57 hils to delay NETosis; and blocking the beta integrin receptor, alpha(M)beta(2,) abolished fibrinogen

58 lagen signal that activates and recruits the integrin receptor alpha2beta1 to further amplify collage

59 a key extracellular matrix protein, and its integrin receptor alpha4beta1, expressed on leukocytes,

60 d that FN increased the expression of the FN integrin receptor alpha5beta1 in a dose- and time-depend

61 d that the RGD sequence in COMP/TSP5 and the integrin receptors alpha5beta1 and alphaVbeta3 on the ch

62 Delta5)) binding motif or the host leukocyte integrin receptor alphaMbeta2 (Fibgamma(390-396A)) bindi

63 inflammation in several diseases through the integrin receptor alphaMbeta2, we tested the hypothesis

64 otably upregulated the expression of its own integrin receptor alphavbeta3 (>200 times).

65 in-RGD itself for binding to three different integrin receptors (alphavbeta3, alphavbeta5, alpha5beta

66 The integrin receptor alphavbeta5 controls two independent f

67 In vitro, RPE cells use the integrin receptor alphavbeta5 for particle binding.

68 acids and glucosamine, binds strongly to the integrin receptor alphaXbeta2 (p150,95, CD11c/CD18).

69 a new mechanism of crosstalk between a beta1 integrin receptor and a G protein-coupled receptor.

70 n-induced adhesion is mediated through beta1 integrin receptor and is IGF-IR-independent.

71 omptly after light onset via the alphavbeta5 integrin receptor and its ligand MFG-E8, thus generating

72 production by CD4(+) T cells via the beta(3) integrin receptor and Opn inhibited IL-10 production via

73 ied the functional inhibition of alphavbeta3 integrin receptor and resulted in decreased alphavbeta3

74 ring the activation state of the alpha5beta1 integrin receptor and suggest that changes in integrin a

75 ealing, which is dependent on binding to the integrin receptor and the NF-kappaB signaling.

76 the synaptic Position Specific 2 (alphaPS2) integrin receptor and transmembrane tenascin ligand are

77 Clustered integrin receptors and activated paxillin (phosphorylate

78 ema7A enhancement of axon outgrowth requires integrin receptors and activation of MAPK signalling pat

79 pecialized regions of the cell surface where integrin receptors and associated proteins link the extr

80 oskeleton via adhesion complexes composed of integrin receptors and associated proteins.

81 sidue found in the cytoplasmic tails of some integrin receptors and C. albicans INT1.

82 ate CNS myelination by interacting with both integrin receptors and dystroglycan receptors, and that

83 ival, and differentiation through binding to integrin receptors and heparan sulfate proteoglycans.

84 closely related to it, can still infect via integrin receptors and induce and transmit the disease t

85 vities in vascular endothelial cells through integrin receptors and induces neovascularization in viv

86 ng to L-arginyl-glycyl-L-aspartate-dependent integrin receptors and prevented vasospasm after SAH.

87 us trophoblast (EVT) invades the decidua via integrin receptors and subsequently degrades extracellul

88 ix via concomitant engagement of alpha5beta1 integrin receptors and syndecan-4, a transmembrane prote

89 ng of the bacterial invasin protein to beta1 integrin receptors and the activation of the small GTPas

90 emonstrate an essential role for alphavbeta5 integrin receptors and their downstream signaling pathwa

91 es FN domains that mediate interactions with integrin receptors and with other FN molecules.

92 tracellular matrix [ECM] signaling by way of integrin receptors) and/or hepatic adaptations that ensu

93 Integrin receptors, and associated cytoplasmic proteins

94 from influenza A virus, potassium channels, integrin receptors, and bacterial kinases.

95 lines expressing different levels of GRP and integrin receptors, and their intracellular localization

96 An integrin receptor antagonist GRGDSP or mitogen-activated

97 binding of [(125)I]echistatin (a competitive integrin receptor antagonist) to integrin receptors with

98 Integrin receptors are dispensable for long-distance mig

99 Laminins and their integrin receptors are implicated in epithelial cell dif

100 cular, the interactions of ECM proteins with integrin receptors are key mediators of these cellular p

101 ing extracellular matrix (ECM) interactions, integrin receptors are likely to be involved.

102 vels of activated, but not wild-type, alpha2 integrin receptors are rapidly down-regulated during cel

103 plays an important role in cell biology, and integrin receptors are the primary molecules involved in

104 ticity are mediated through beta1-containing integrin receptors, are associated with integrin-depende

105 ophils from beta2 null mice identified beta2 integrin receptors as a master switch for NET induction.

106 small GTPases Rap1a and Rap1b, downstream of integrin receptors as miR149 targets, providing an expla

107 identified fibulin-5, a vascular ligand for integrin receptors, as a suppressor of lung cancer invas

108 icient livers had enhanced signaling via the integrin receptor at early times (0.5 to 1 hour) after F

109 ronectin binding to the purified alphaVbeta3 integrin receptor at low nanomolar concentration and sho

110 with the extracellular matrix (ECM) through integrin receptors at adhesion sites termed point contac

111 e that neuronal APP colocalizes with beta(1) integrin receptors at sites of focal adhesion, suggestin

112 athways, as well as a 20% reduction in beta1-integrin receptors at the cell surface and impaired fibr

113 types (types A and O) after interaction with integrin receptors at the cell surface.

114 of concept, we imaged the tension exerted by integrin receptors at the interface between living cells

115 owed that MerTK helps control POS binding of integrin receptors at the RPE cell surface as a negative

116 examined the hypothesis that an abnormal ECM-integrin receptor axis contributes to BM megakaryocytosi

117 ates hippocampal synaptic physiology through integrin receptors, because integrin function-blocking r

118 Integrin receptors bind to adhesion ligand (e.g. arginin

119 embly through its RGD motif, suggesting that integrin receptor binding does not mediate MAGP-2-induce

120 ue since in complementary experiments use of integrin receptor binding ligand, GRGDS peptide, offered

121 h may be of use to elucidate the kinetics of integrin receptor binding to ECM proteins for homeostati

122 and experiments to evaluate the kinetics of integrin receptor binding to hepatic ECM proteins.

123 interaction, and this stabilization required integrin receptor binding to its ECM ligand.

124 creases in intracellular pH (pHi) occur upon integrin receptor binding to matrix proteins and in tumo

125 peting with fibrinogen for alpha(IIb)beta(3) integrin receptor binding.

126 this study is to test if the addition of an integrin-receptor-binding arginine-glycine-aspartic acid

127 muscle degeneration in zebrafish with intact integrin receptors but does not improve motility.

128 duced inside-out activation of heterodimeric integrin receptors by a mechanism involving the recruitm

129 Activation of integrin receptors by adhesion to laminin-1 or Semaphori

130 nts (FRET), we determined that engagement of integrin receptors by invasin caused elevated levels of

131 Furthermore, force applied to these integrin receptors by magnetic beads activated TACE and

132 n hemostasis and the inactivation of beta(3) integrin receptors by pathogenic hantaviruses suggest th

133 A subset of integrin receptors can link to the adapter protein Shc a

134 A ligand of several integrin receptors, CCN1 acts through integrin alpha6bet

135 n binding motif recognized by the microglial integrin receptor CD11b/CD18 inhibits perivascular micro

136 The integrin receptor CD11b/CD18 is normally kept in a low a

137 ephrin's role in transmitting signals to the Integrin receptor complex, we conducted genetic studies

138 esized that Nephrin transmits signals to the Integrin receptor complex, which mediates podocyte adhes

139 that forms the alphaIIbbeta3 and alphavbeta3 integrin receptor complexes.

140 Integrin receptors, composed of transmembrane alpha and

141 nal force by Muller cells primarily involves integrin receptors containing alpha2 and beta1 subunits.

142 an inhibitor of alphavbeta3 and alphavbeta5 integrin receptors, demonstrated minimal toxicity and du

143 ated that an antibody to CD11/CD18 leukocyte integrin receptor did not reduce infarct size in patient

144 Surprisingly, we found that integrin receptors dissociate streptavidin-biotin tether

145 ward signaling mechanism wherein F-actin and integrin receptors drive contact formation between phago

146 rons modulate the functional distribution of integrin receptors during chemorepulsion induced by myel

147 recently shown that FMDV serotypes utilizing integrin receptors enter cells via a clathrin-mediated m

148 D 121974), which targets the alpha(v)beta(3) integrin receptor expressed on neovasculature, could inc

149 high affinity to the extracellular domain of integrin receptors expressed in dendritic shaft and spin

150 lude that reelin binds with high affinity to integrin receptors expressed in SNSs and thereby activat

151 type-IV collagen were shown to interact with integrin receptors expressed on the surface of endotheli

152 and inhibit the adhesion of alpha(v)beta(3) integrin receptor-expressing WM-115 melanoma cells.

153 Expression of HGK mutants modulated integrin receptor expression and had a striking effect o

154 R-2 and that lineage-specific differences of integrin receptor expression contribute to the distinct

155 in the GC was inhibited, thus its associated integrin receptors failed to translocate to the cell sur

156 n of the activation state of the alpha5beta1 integrin receptor for fibronectin.

157 As a major integrin receptor for the organs, we compared CD103 expr

158 Integrin receptors for cell adhesion to extracellular ma

159 Integrin receptors for extracellular matrix are critical

160 Integrin receptors for the extracellular matrix and rece

161 CM) adhesion molecules and the expression of integrin receptors for these molecules (termed ECM remod

162 ins specific laminins, and RPE cells express integrin receptors for those laminins.

163 Analysis of the integrin receptors for VCAM-1 showed that in beta7 integ

164 Among synaptic CAMs, the integrins, receptors for extracellular matrix proteins a

165 e applied both types of tPAINT probes to map integrin receptor forces in live human platelets and mou

166 A unique aspect of integrin receptor function is the transmission of bidire

167 ency of plastin thus separates the classical integrin receptor functions of adhesion and spreading fr

168 MDV) mediates cell entry by attachment to an integrin receptor, generally alphavbeta6, via a conserve

169 The alphavbeta6 integrin receptor has been shown to be overexpressed on

170 The heterodimeric transmembrane alphav integrin receptors have recently emerged as potential ta

171 fferentiation, in particular laminin and its integrin receptors, have been identified using mammary e

172 . elegans, we have previously shown that the integrin receptor heterodimer INA-1/PAT-3 promotes netri

173 In this report, we explored how integrins, receptors important for monocyte migration to

174 strate a functional role for the alpha7beta1 integrin receptor in CNS neurons.

175 hat functional modulation of the alphavbeta3 integrin receptor in prostate cancer cells is required f

176 te role for a structural ECM protein and its integrin receptor in the development of the left-right a

177 The role of integrin receptors in cell engraftment was analyzed with

178 The alpha(v)beta(3) integrin receptors in colon cancer cells are successfull

179 lphav integrin subunits, we downregulate all integrin receptors in hepatocytes.

180 copy to investigate the pN forces exerted by integrin receptors in living cells.

181 teraction of nanotopographical features with integrin receptors in the cells' focal adhesions alters

182 s point out a novel role of collagen-binding integrin receptors in the control of growth hormone/IGF-

183 The presented strategy of targeting integrin receptors in the retina could be of utmost valu

184 verned by multiple signal cascades including integrin receptors, in particular integrin alphaVbeta3.

185 n response to signals from laminin-activated integrin receptors; in the absence of myosin II activity

186 eins talin and its cofactor, kindlin, to the integrin receptors induces integrin activation and clust

187 ling mechanisms can be initiated by a single integrin receptor interacting with the same ligand when

188 e binding of fibrinogen to its alphaIIbbeta3 integrin receptor, internalization of the alphaIIbbeta3

189 incorporating the structures of selectin and integrin receptors into a conceptual framework based on

190 The alpha(v)beta(3) integrin receptor is an important cancer target due to i

191 The alpha(5)beta(1) integrin receptor is believed to be involved in tumor me

192 The integrin receptor is near the Arg-Gly-Asp (RGD) recognit

193 The alphaIIb/beta3-integrin receptor is present at high levels only in mega

194 The turnover of integrin receptors is critical for cell migration and ad

195 ting the gastrin-releasing peptide (GRP) and integrin receptors is reported.

196 Cell adhesion via integrin receptors is well known to trigger FAK signalin

197 c-Raf/MEK1/2/p38/ERK1 MAPK pathway in alpha1 integrin receptor knockout ECs.

198 in vivo but failed to do the same in alpha1 integrin receptor knockout mice.

199 al parameters such as matrix ligand and cell integrin receptor levels are held constant, maximal cell

200 ects, were collected to assess chemokine and integrin receptor levels on monocytes.

201 Precise documentation of integrin receptor levels will allow appropriate selectio

202 To understand how variations of the integrin receptor ligation may alter cytolytic activity

203 like receptors, G-protein-coupled receptors, integrins, receptor-like kinases, and caspases have emer

204 attachment to the extracellular matrix where integrin receptors link extracellular matrix to the acti

205 -ECM contact area and enhances engagement of integrin receptors, locally amplifying ECM input to inte

206 lateral mobility, and microclustering of the integrin receptor lymphocyte function-associated antigen

207 Binding of LtxA to its beta2 integrin receptor (lymphocyte function-associated antige

208 interaction of fibrinogen with the microglia integrin receptor Mac-1 (alpha(M)beta(2), CD11b/CD18) is

209 respect to several proteins, especially the integrin receptor Mac-1, the Fc-gamma receptor I (Fcgamm

210 termediates for growth factor, cytokine, and integrin receptors, many of which have been implicated i

211 Integrin receptors mediate adhesive events that are crit

212 -CSNP-RGD system showed increased uptake via integrin receptor mediated endocytosis, triggered enhanc

213 died examples, ECM promotes survival through integrin receptor-mediated activation of focal adhesion

214 We tested the strength of the integrin receptor-mediated linkages to the cytoskeleton

215 tion of fibronectin with beta3 but not beta1 integrin receptors mediates the survival pathway.

216 hav antagonist (compound 39, 4-40 nM for the integrin receptors named above) possessing excellent ora

217 rin alpha7beta1 is the major laminin binding integrin receptor of muscle cells.

218 These data indicate that Mfge8 binding to integrin receptors on ASM opposes the effect of allergic

219 alpha(M)beta(2) integrin receptors on myeloid cells mediate the adhesion

220 oping epithelial duct, and binds to alpha(v) integrin receptors on myoepithelial cells leading to MAP

221 s by binding to various molecules, primarily integrin receptors on the cells.

222 of the glycoprotein IIb/IIIa (alphaIIb/beta3 integrin) receptor on the surface of activated platelets

223 ity (1.4 to >3 logs) for the alpha(v)beta(6) integrin receptor over the other alpha(v) integrins as d

224 sequence have high affinity for alphavbeta3 integrin receptors overexpressed in tumor cells.

225 y, such as disconnections within the antigen/integrin receptor pathway and increased negative regulat

226 ent evidence of a functional interplay among integrin receptors, PKCepsilon, and protein kinase B (PK

227 The alpha2beta1 integrin receptor plays a key role in angiogenesis.

228 Integrin receptor plays key roles in mediating both insi

229 Thus, the interaction between KSHV and its integrin receptors plays a key role in regulating rapid

230 indicate that partial activation of EGFR by integrin receptors plays an important role in mediating

231 tracellular matrix (ECM) signaling by way of integrin receptors, plays an important role in regulatin

232 ubspecialization of T3 and T4 binding to the integrin receptor pocket.

233 ptidergic targets, such as peptide GPCRs and integrin receptors, possess significantly higher median

234 means by which hantavirus binding to beta(3) integrin receptors prevents platelet activation.

235 The RGDFC peptide interaction with the integrin receptor provides a bright and fluctuating SERS

236 eurons that, acting through pyramidal neuron integrin receptors, provides a signal for dendritic spin

237 ments and cell migration and invasion at the integrin receptor-proximal region.

238 1b/CD18 (Mac-1 [macrophage-1 Ag]), a surface integrin receptor, recognized extracellular dsRNA and in

239 Integrin receptors regulate normal cellular processes su

240 ro, consistent with its putative function in integrin receptor regulation.

241 tes (OLs) to fibronectin via alpha(v)beta(3) integrin receptors rendered the cells more resistant to

242 e genital tract have been characterized, the integrin receptor required for Chlamydia-specific CD4(+)

243 tin (FN) through alpha3beta1 and alpha5beta1 integrin receptors, respectively.

244 r targeting of nanochains to the alphavbeta3 integrin receptor resulted in a 18.6-fold greater drug d

245 enhance interactions with the Met and beta1-integrin receptors, resulting in Met/beta1-integrin co-i

246 tors that remodel RPE basement membrane, and integrin receptors sense these changes triggering Rho GT

247 ited to and activated specifically in alpha6 integrin receptor signaling complexes in the lens equato

248 orks, and it is this activity, combined with integrin receptor signaling, that controls neuronal surv

249 tivity to promote synapse remodeling through integrin receptor signaling.SIGNIFICANCE STATEMENT The a

250 sion-independent manner and are comprised of integrin receptors, signaling, and cytoskeletal-associat

251 identified several chemokines and members of integrin receptor-signaling pathways, including CCL3, CC

252 Integrin receptor signals are costimulatory for mitogene

253 Herein, we report the integrin receptor specificity of novel peptide-dye conju

254 The integrin receptor specificity of this radiotracer was de

255 es of mice lacking platelets or the platelet integrin receptor subunit alphaIIb established that the

256 Integrin alpha(3) is a transmembrane integrin receptor subunit that mediates signals between

257 Because we detected reelin, alpha3-integrin receptor subunits, and disabled-1 immunoreactiv

258 esion is regulated through the modulation of integrin receptors such as alpha(V)beta(3).

259 esion is regulated through the modulation of integrin receptors such as alpha(v)beta(3).

260 Further experiments suggested that beta2 integrin receptors such as complement receptor 3 (CR3) a

261 -Asp through which it interacts with several integrin receptors, such as the alpha(V)beta(3)-integrin

262 Signaling pathways activated by integrin receptors suppress anoikis.

263 e data provide direct evidence that uPAR and integrin receptors synergistically regulate the levels o

264 f integrin beta1, a major constituent of the integrin receptors targeted by decidual laminins, also i

265 spreading is regulated by signaling from the integrin receptors that activate intracellular signaling

266 ic RGD peptide selectively binds to alpha(v) integrin receptors that are highly expressed in metastat

267 affinity ( approximately 10 to 30 nmol/L) to integrin receptors that are overexpressed on the surface

268 ecular imaging agents to detect cell surface integrin receptors that are present in human cancers.

269 ) is a PET tracer binding to alpha(v)beta(3) integrin receptors that are upregulated after myocardial

270 ation of CD11b, which is a CD18 subfamily of integrin receptors that is highly expressed on APCs, abo

271 s present in the oligosaccharidic portion of integrins, receptors that interact with extracellular ma

272 After in vivo blocking of integrin receptors, the imaging signal after the adminis

273 or, uPAR, can form functional complexes with integrin receptors thereby modulating integrin activity.

274 udies have examined the contribution of this integrin receptor to cancer progression and they have re

275 e number of cells adhering via their beta(1) integrin receptor to collagen type II or chondroadherin

276 high-affinity "OA02" peptide against alpha-3 integrin receptor to improve the tumor-targeting specifi

277 s is mediated by the binding of cell-surface integrin receptors to peptide ligands from the extracell

278 odeling or by signaling through cell-surface integrin receptors to promote cell adhesion, migration,

279 We hypothesized that IECs use integrin receptors to recognize pathogens and initiate i

280 teins that interact with each other and with integrin receptors to regulate cell growth and movement.

281 affinity of a cell-adhesive peptide to cell integrin receptors to study dynamic cell adhesion and ce

282 se (Ilk) is a scaffold and kinase that links integrin receptors to the actin cytoskeleton and to sign

283 rin-linked kinase and is involved in linking integrin receptors to the cytoskeleton.

284 regulated by the ligand-binding activity of integrin receptors, transmembrane proteins that bind to

285 the associated transmembrane receptors (e.g. integrins, receptor-type tyrosine kinases).

286 ell as NC1 domain binding to alpha(V)beta(3) integrin receptor via modification of critical arginine

287 rus (FMDV) initiates infection by binding to integrin receptors via an Arg-Gly-Asp (RGD) sequence fou

288 that the binding of gB via its RGD motif to integrin receptors was not responsible for the observed

289 ity to adhere to the surrounding ECM through integrin receptors, we examined the hypothesis that an a

290 l expression and the involvement of specific integrin receptors were assessed by immunodetection, RT-

291 Loss of activity of the beta1-integrin receptor, which controls adhesion to collagen,

292 d, retargeting the virus to the alphav beta3 integrin receptors, which are overexpressed in tumor vas

293 he alphavbeta3, alphavbeta5, and alpha5beta1 integrin receptors, which play important roles in human

294 t activation and binding of additional beta1 integrin receptors, which promotes cytoskeletal remodeli

295 competitive integrin receptor antagonist) to integrin receptors with a K(i) of 22 pM and with a Hill

296 t of the binding affinity to alpha(v)beta(3) integrin receptors with respect to the monovalent RGD pe

297 Engagement of integrin receptors with the extracellular matrix induces

298 Stimulating integrin receptors with the RGD ligand liberated by MMP

299 The linkage of heterodimeric (alpha/beta) integrin receptors with their extracellular matrix ligan

300 membranes, and visualize the arrangement of integrin receptors within endoplasmic reticulum and adhe