ライフサイエンスコーパス: integrity

1 ting induction of genes that preserve skin's integrity.

2 ssing, a function vital to epidermal barrier integrity.

3 regulators of perineuronal net formation and integrity.

4 HSCs) remain quiescent to preserve long-term integrity.

5 occludin, key mechanisms underlying vascular integrity.

6 fully, and display no loss of outer membrane integrity.

7 ound no effect of field exposure on membrane integrity.

8 ognitive networks, as indexed by hippocampal integrity.

9 ests that cohesin is required for their full integrity.

10 ntial role of the TLR2-responses in vascular integrity.

11 ontrols mitotic morphogenesis and epithelial integrity.

12 types of lesions in DNA, threatening genomic integrity.

13 or imaging metrics of increased white matter integrity.

14 ses tumorigenesis by maintaining the genomic integrity.

15 isms that control gene expression and genome integrity.

16 agents, appears to protect epidermal barrier integrity.

17 ne components and its direct effects on cell integrity.

18 stream of RAC1 and depends on NCKAP1 for its integrity.

19 and neuroinflammation, impacting on PVI/PNN integrity.

20 the mitochondrion is essential for cellular integrity.

21 in order to preserve genetic and epigenetic integrity.

22 lates S phase progression to maintain genome integrity.

23 efficiently repair DSBs to preserve genomic integrity.

24 f a broader system for maintaining chromatin integrity.

25 deling of bone matrix to maintain structural integrity.

26 itiate defensive reflexes that ensure airway integrity.

27 urochemical concentrations, and white matter integrity.

28 nsactions vital to the maintenance of genome integrity.

29 components in those AVM cases affecting bone integrity.

30 to preserve redox homeostasis and stem cell integrity.

31 tion machineries, and hence threaten genomic integrity.

32 by reducing levels of LPS and outer membrane integrity.

33 e roles, from neuronal development to muscle integrity.

34 nmental stress and cell adhesion and barrier integrity.

35 icroenvironmental niche for surveying tissue integrity.

36 ment response through affecting white matter integrity.

37 n aneurysm patients with altered aortic wall integrity.

38 capture partly different aspects of network integrity.

39 es form at the PM and help maintain membrane integrity.

40 functions and how they help maintain genome integrity.

41 DNA methylation homeostasis to ensure genome integrity.

42 stress conditions, thereby maintaining cell integrity.

43 umes, and worse white matter microstructural integrity.

44 established role in safeguarding the genomic integrity.

45 tophagy must be inhibited to maintain genome integrity.

46 TrkC is essential for maintaining glomerular integrity.

47 metabolites, while retaining their membrane integrity.

48 esting a role for zinc in maintaining genome integrity.

49 son proliferation poses a threat to germline integrity.

50 e replication, as well as maintaining genome integrity.

51 haracterized by impaired blood-brain barrier integrity.

52 -R) conflicts are profound threats to genome integrity.

53 how greater apoptosis and decreased synaptic integrity.

54 A replication and the maintenance of genomic integrity.

55 plexity, data collection, and implementation integrity.

56 e differentiation and controlling epigenetic integrity.

57 in RNA/DNA processing and maintaining genome integrity.

58 or-suppressing mechanism that ensures tissue integrity.

59 pillary pericytes(15-19), which maintain BBB integrity(20-22).

60 The Chesapeake Basin-wide Index of Biotic Integrity, a benthic macroinvertebrate multimetric index

61 -time in 18 biomarkers tracking organ-system integrity across 12 years of follow-up in n = 954 member

62 nto conserved mechanisms that promote genome integrity across generations.

63 state, but also promotes blood brain barrier integrity, adaptive immunity, and activation of microgli

64 gut and has been used to confirm anastomotic integrity after pancreatic surgery.

65 rotease release, suggesting altered membrane integrity after the field exposure.

66 es, and the development of biomarkers of BBB integrity along with systems biology approaches, should

67 is primarily the result of enhanced vascular integrity and accelerated apoptosis of infiltrated monoc

68 d data was manually curated to preserve data integrity and accuracy.

69 amework magnets while maintaining structural integrity and additional function.

70 n EB, encoding proteins influencing cellular integrity and adhesion.

71 Loss of gut mucosal integrity and an aberrant gut microbiota are proposed me

72 cteria, the role of these systems in genomic integrity and antibiotic lethality is not understood, in

73 nergy balance in IECs and thereby epithelial integrity and barrier function.

74 ssed samples preserve their architecture and integrity and can be paraffin-embedded for subsequent hi

75 ain (NP) synthesis is essential for proteome integrity and cellular health.

76 at CEN contributes to defects in kinetochore integrity and CIN.

77 ive damage to DNA is a threat to the genomic integrity and coding accuracy of the chromosomes of all

78 ntarctic blue carbon and maintain scientific integrity and conservation for the positive societal val

79 s altered lysosomal state protects host cell integrity and contributes to the containment of the path

80 the cytosol, supporting normal blood vessel integrity and development.

81 c-COF ZnPc-pz-I(2) maintains its structural integrity and displays enhanced conductivity by 3 orders

82 e disassembly, and led to defects in nuclear integrity and DNA damage.

83 ows optical control over microtubule network integrity and dynamics, cell division and survival, with

84 of palmitoyl-proteins is important for axon integrity and for axon-to-soma retrograde signaling, a p

85 f cell-cell communication at the NMJ for the integrity and full functionality of this synapse, the co

86 at play an essential role in maintaining the integrity and function of the glomerular filtration barr

87 and immunity-critically contribute to thymic integrity and function.

88 agement is no longer tenable to maintain the integrity and functionality of aquatic ecosystems.

89 r invasion, and (4) preserves the structural integrity and functionality of HUVEC-lined microfluidic

90 ic, we examined white matter microstructural integrity and gray matter cortical thickness/density dif

91 of light on the taxonomic composition, cell integrity and growth responses of microbial communities

92 sis as they relate to the loss of glycocalyx integrity and highlight the contribution of several prot

93 Human skin provides both physical integrity and immunological protection from the external

94 GS cells exhibited the loss of mitochondrial integrity and increased expression of the microtubule-as

95 y acids and bile acids, improved gut barrier integrity and increased intestinal T regulatory cells.

96 slational modifications of ACTN4 on podocyte integrity and kidney function is not known.

97 ecessary to maintain mitochondria functional integrity and localization to synapses.SIGNIFICANCE STAT

98 ulator of genome maintenance that ensures Xi integrity and may, more broadly, predict DNA repair outc

99 prominent disruptions in fiber orientation, integrity and myelination.

100 ion of key structural proteins alters tissue integrity and organ function.

101 all of which are precursors for impaired gut integrity and performance.

102 adelta T cell subsets is to maintain barrier integrity and prevent microorganisms from breaching the

103 CRT disassembly to maintain nuclear envelope integrity and proper ER architecture.

104 etail but also substantially improves sample integrity and protein distribution across the vitreous i

105 ssociated with poor brain WM microstructural integrity and reduced cerebral perfusion, likely due to

106 atment associates with intestinal epithelium integrity and reduced damage caused by diminished recrui

107 eration while faithfully maintaining genomic integrity and regenerative potential remains elusive.

108 cluding maintenance of protein and organelle integrity and regulation of metabolism(4).

109 sequence on the regulation of airway barrier integrity and S. pneumoniae disease.

110 When assessing the integrity and stability of large molecular complexes suc

111 anide polyMOF membrane exhibits not only the integrity and temperature sensing behaviour of the Ln-MO

112 sis and recycling to maintain its structural integrity and that impairment of the exocyst complex lea

113 intervention to limit the decline of barrier integrity and the resulting systemic inflammation that o

114 can be linked to p120-catenin in epithelial integrity and turnover, and additional phenotypes that s

115 bject recruitment while maintaining research integrity and without overburdening patients or staff.

116 serve mitochondrial function, adipose tissue integrity, and beta-cell mass during obesity is a major

117 dly to manage cellular metabolism, organelle integrity, and cell fate.

118 ollagen, improving mechanical properties and integrity, and decreased the enzyme-mediated degradation

119 ids become highly permeable, lose structural integrity, and eventually burst, releasing their content

120 phospholipid trafficking and outer membrane integrity, and includes an ABC transporter, MlaFEDB.

121 syndrome, spared gut function and epithelial integrity, and spared cell death in crypt base columnar

122 ps includes characterizing the organization, integrity, and stability of the inserted DNA and evaluat

123 n identified, yet the maintenance of genomic integrity appears problematic.

124 ng the envelope properly and maintaining its integrity are matters of life and death for bacteria.

125 Here, we identify intestinal barrier integrity as an important checkpoint in translating auto

126 IMP3 transgenic mice showed compromised bone integrity as opposed to [-1A]TIMP3 mice.

127 h phagosomes to maintain phagosomal membrane integrity as the fungal pathogen Candida albicans expand

128 ional domains that play roles in UAF complex integrity, assembly, and biological function, and provid

129 visual fields (Carl Zeiss Meditech), macular integrity assessment perimetry, OCT, motion discriminati

130 ch we have characterized pathological tissue integrity, barrier function and metabolic stability over

131 nregulates CAR assembly in S. pombe when its integrity becomes compromised during cytoskeletal damage

132 ility to partition into and disrupt membrane integrity but with no known antiviral activity, were tes

133 plays a crucial role in maintaining genomic integrity by responding to a large spectrum of DNA damag

134 r Shrub in maintaining septate junction (SJ) integrity by transporting the claudin Megatrachea (Mega)

135 lerated degradation, but adequate mechanical integrity can be expected for Zn alloys when considering

136 production and environmental stress on grape integrity, can increase bacterial diversity and specific

137 re under robust molecular control, including integrity check and repair mechanisms.

138 reads from known genomes and evaluating the integrity, contiguity and accuracy of the assembly using

139 r goal to advance this research program with integrity despite the current incentives in science.

140 reasing the occurrence of age-related vulval integrity disorder.

141 he role of pro-survival genes in cancer cell integrity during clonal evolution in non-small cell lung

142 f a mechanism to protect 3D genome structure integrity during DNA damage repair.

143 Protecting replication fork integrity during DNA replication is essential for mainta

144 omembrane system maintain their identity and integrity during growth or stress conditions by homeosta

145 ic neutrophilic inflammation preserve tissue integrity during infection.

146 in removal and the maintenance of chromosome integrity during meiosis.

147 n of keratinocytes by maintaining centrosome integrity during mitosis through interacting with alpha-

148 e it is essential to guarantee the framework integrity during utilization.

149 with the neurological syndrome known as body integrity dysphoria express a desire to amputate seeming

150 y be useful in maintaining microbial profile integrity, especially for samples collected off-site and

151 ium and are critical for blood-brain-barrier integrity, express CD19.

152 Here, we assess ribosomal integrity following oxidative stress both in vitro and i

153 ily high rate of turnover that maintained JE integrity for 1.4 y in mice.

154 to water soaking, thus retaining structural integrity for easy collection of lead after damage.

155 , gray matter volume, and white matter tract integrity (fractional anisotropy, FA) within brain regio

156 s response, and maintenance of cell membrane integrity, further confirm this phenomenon.

157 to high standards of ethical and scientific integrity, given that human lives are at stake.

158 were characterized by largely intact genome integrity, high immune infiltration, and younger patient

159 , (i) fractional anisotropy as a measure for integrity; (ii) total number of fibres; and (iii) percen

160 their effects on keratinocytes, skin barrier integrity, immune activation, and microbial ecology.

161 ation and transcription and maintains genome integrity in a Top1-dependent manner.

162 Mobile genetic elements threaten genome integrity in all organisms.

163 e measurement implicate cell wall metabolism/integrity in betaCA3-mediated basal immunity under both

164 fine the role of E2F2 in maintaining genomic integrity in breast cancer.

165 screen identified mutations that promote NE integrity in cmp7Delta cells.

166 ding our biophysical understanding of genome integrity in health and disease.

167 re, we show that kindlin-2 maintains spindle integrity in mitotic human cells.

168 uctural network had a reduced efficiency and integrity in multiple sclerosis relative to healthy cont

169 its own mechanical state to maintain genome integrity in response to deformation.

170 t relationship between H3K27me3 and telomere integrity in stem cell lineage commitment that may have

171 al property of cells, essential for cellular integrity in the face of osmotic challenges.

172 , whereby it promotes and maintains vascular integrity in the tumor microenvironment by contributing

173 2A), were used to study hippocampal synaptic integrity in vivo in an equal number (n = 12) of subject

174 hannel lifetimes without disrupting membrane integrity, in a manner consistent with changes in membra

175 umorigenesis in mice by reducing gut barrier integrity, increasing tumor bacterial load, promoting ex

176 physical discontinuities and restore tissue integrity is a fundamental process in normal development

177 tests, revealed 19 new cases of genes whose integrity is regulated by IGEs (including dut, eccCa1, g

178 Endothelial integrity is vital for homeostasis and adjusted to tissu

179 ells caused impairment of epithelial barrier integrity, leading to high susceptibility to DSS-induced

180 or desirable, as it can damage the polymer's integrity, leading to loss of function and properties.

181 posite measures of biological age and system integrity: Levine Method, homeostatic dysregulation, Kle

182 gh-quality microbiome research relies on the integrity, management and quality of supporting data.

183 We also assessed white matter integrity measured by fractional anisotropy (FA) and mea

184 The relationship between gut integrity, microbial translocation, and inflammation in

185 Cellular integrity, migration, and genome-wide gene expression ch

186 nce of preserving both the global structural integrity of antigens and local conformational flexibili

187 al Na(+) channel clusters and the structural integrity of axons.

188 nd free hemin, which are known to damage the integrity of blood vessel walls.

189 odent touchscreen tasks to assess functional integrity of brain circuits and multiple cognitive domai

190 Here we report that the integrity of CA activity in the brain is necessary for t

191 vestment risk and ensuring the environmental integrity of carbon emission offsets.

192 We investigated the integrity of cardiac beta-receptor responsiveness, an im

193 To shed light on the integrity of clinical trial results, this paper systemat

194 e-dimensional (1D) GC to GCxGC, ensuring the integrity of data as conversion is made.

195 factor D (VEGFD) is required for structural integrity of dendrites and cognitive abilities.

196 derstanding of how EMC enables insertion and integrity of diverse clients, from tail-anchored to poly

197 lusion: These findings suggest that impaired integrity of dopaminergic nigrostriatal nerve terminals

198 tance for both animal welfare and scientific integrity of effective welfare assessment in non-human p

199 lastic carbon shell maintains the structural integrity of electrode material.

200 hybridization raise concerns on the genetic integrity of endangered species.

201 Thus, we explored the integrity of forebrain mitochondria in Fmr1 knockout mic

202 ally depend on the structural and functional integrity of frontoparietal networks.

203 e stability is essential for the cell as the integrity of genomic information guaranties reproduction

204 We conclude that the integrity of Golgi-dependent copper homeostasis mechanis

205 uced a rapid drop in the endothelial barrier integrity of HLMVECs.

206 the HIV-1 reservoir, focusing on the genetic integrity of individual proviruses independent of transc

207 nal MRI (fMRI) studies have reported altered integrity of large-scale neurocognitive networks (NCNs)

208 crucial role in the maintenance and genetic integrity of Lgr5(+)ISC under physiological and stress c

209 We discovered that the mechanical integrity of LiF is easily compromised during plating, m

210 n, neuromelanin-sensitive MRI to measure the integrity of locus coeruleus pigmented neurons, and 18F-

211 n addition to contributing to the structural integrity of membranes, sphingolipid metabolites, such a

212 information, such as cellular stress, to the integrity of microtubules in order to instruct neurorege

213 microarchitecture and the cellular/molecular integrity of mini pig hard tissues, then demonstrated th

214 of a progressive deterioration of functional integrity of mitochondria that establishes a historic re

215 DNA expression acts as a stress test for the integrity of mitochondrial genomes and sets the stage fo

216 ays that potentially affect the function and integrity of multiple tissues, impacting both ongoing im

217 stasis at the axon-myelin interface, and the integrity of myelinated axons.

218 cts in microstructural gray and white matter integrity of optic tract, and somatosensory and visual c

219 tic elements, such as LINE-1, to protect the integrity of our genome.

220 use gas emissions; monitoring the mechanical integrity of reservoir formations is essential for effec

221 es learning, suggesting preserved functional integrity of supporting brain circuits.

222 The organizational integrity of the adaptive immune system is determined by

223 eir contribution, we examined the structural integrity of the alveolar-capillary barrier in archival

224 a mouse model of colitis by maintaining the integrity of the apical junctional complex and its assoc

225 in maintaining the structure, functions and integrity of the aquatic ecosystem.

226 Tumours are known to compromise the integrity of the BBB, resulting in a vasculature known a

227 y's immune cells, frequently compromises the integrity of the blood-brain barrier (BBB), and infects

228 Furthermore, we demonstrate that the integrity of the CCHC motifs in the Gag NC domain is dis

229 ivates bacteria by physically disrupting the integrity of the cell membrane.

230 The structural and functional integrity of the cell wall needs to be constantly monito

231 conserved alpha-helix 30 interferes with the integrity of the cell wall, disrupts cell division, cell

232 trol of these contractions, gray matter (GM) integrity of the cerebellum, and disease severity using

233 production of collagens, loss of structural integrity of the cuticle, and impaired barrier function.

234 we show that Sac1 is required for structural integrity of the Drosophila retinal floor.

235 ring antireflux procedures to the functional integrity of the EGJ.

236 tions to treat reflux attempt to restore the integrity of the EGJ.

237 esilience in the mother, suggesting that the integrity of the embryo is monitored by the vulva to det

238 t of rapamycin complex 1 (TORC1) control the integrity of the endolysosomal homeostasis and cellular

239 is able to control structural and functional integrity of the epidermal layer in developing Xenopus e

240 aust, nanoparticles, and microplastic on the integrity of the epithelial barriers in the context of e

241 l development of zebrafish by supporting the integrity of the EVL, likely by mediating cell adhesion

242 In Group 2, the integrity of the external limiting membrane at 3 months

243 of NCSTN to its mature form and impairs the integrity of the gamma-secretase complex as well as its

244 uction of viable gametes and maintaining the integrity of the genomes they carry, it remains controve

245 Eukaryotic cells must accurately monitor the integrity of the mitochondrial network to overcome envir

246 us-evoked fluctuations without affecting the integrity of the network.

247 mprove both neurotransmission and structural integrity of the NMJ in a mouse model of DOK7-CMS.

248 Comparisons of shape and integrity of the nuclear envelope and its resistance to

249 ation plays a pivotal role in sustaining the integrity of the ocular surface.

250 Some virulence factors serve to maintain the integrity of the outer membrane, including DolP (formerl

251 he mechanism while confirming the structural integrity of the polyolefin-polar blocks.

252 experiments was essential in confirming the integrity of the POM, the catalyst, and the MOF after ca

253 The integrity of the restoration is constantly challenged by

254 A entry-exit site in broadly maintaining the integrity of the transcriptome.

255 n the ventral prefrontal tract, although the integrity of the uncinate fasciculus remained unchanged.

256 olution diffusion imaging, we quantified the integrity of the uncinate fasciculus using generalized f

257 ogical prediction is that differences in the integrity of the white matter tracts that connect these

258 alytical tools to monitor the conformational integrity of therapeutic-proteins during manufacture and

259 Integrity of this network, which includes the hippocampu

260 ve stress in Caco-2 cells, and preserved the integrity of tight junctions.

261 y an essential role in organogenesis and the integrity of tissue architecture and function.

262 3D) chromatin architecture can influence the integrity of topologically associating domains (TADs) an

263 barrier function, small molecule uptake, and integrity of transcription and translation.

264 chaperome genes and assessed the structural integrity of two crucial HSR regulators - Heat Shock Fac

265 ts exhibit sensitivity to the conformational integrity of various forms of rHuEPO and as such represe

266 s an important role in maintaining cell wall integrity of xylem vessels, physiological and molecular

267 ts were associated with altered white matter integrity (p = 2.5x10-7) in brain images from 1,738 youn

268 ets are blood cells responsible for vascular integrity preservation.

269 ed that heating disrupted the bean cell wall integrity, protein matrix and starch granules more sever

270 processing, translation, metabolism, nuclear integrity, protein trafficking, and cytoskeletal-microtu

271 omponent loadings reflecting connectome-wide integrity (|r(nodes)| = .420; |r(edges)| = .583), sugges

272 endrocyte entities was termed as neuron-glia integrity recently.

273 The accompanied loss of tissue integrity, recognition by cellular immunity, and cell de

274 unction of the NEIL3 Zf-GRF repeat in genome integrity remains unknown.

275 al role in preserving the maternal epigenome integrity required for proper zygotic genome activation

276 development, bone deposition, and mechanical integrity, respectively.

277 The list of regulated gene integrity (RGI) cases has been slow-growing because IGEs

278 gical processes ranging from cell structural integrity, signaling, and cell proliferation to cell dea

279 to disrupt cell cycle progression and genome integrity, so it is highly likely that cells require a n

280 d generated monolayers with enhanced barrier integrity, so that directional (basal or apical) 5HT sec

281 Clinical restoration of tooth integrity, sometimes involving physical and chemical ste

282 crosstalk in maintaining epithelial barrier integrity, suggesting that angiogenin may serve as a new

283 u-Sn intermetallic shows terrific mechanical integrity that resists the plastic deformation during th

284 his pathway is critical for fungal cell wall integrity, the hexosamine biosynthesis enzymes represent

285 cial stress alters blood-brain barrier (BBB) integrity through loss of tight junction protein claudin

286 otentially compromises the reservoir storage integrity through pore fluid pressure build-up.

287 ome of replication stress in terms of genome integrity, tumorigenesis, and response to chemotherapy.

288 portant fork protector that preserves genome integrity under replication perturbation.

289 reducing ends were exposed and cell membrane integrity was compromised.

290 Incomplete endothelial integrity was confirmed as a key factor of neointimal fo

291 Postoperative EZ integrity was restored in 52 eyes (60%), ELM integrity w

292 integrity was restored in 52 eyes (60%), ELM integrity was restored in 54 eyes (62%), and cystoid spa

293 Indices of network integrity were calculated for each subject, network, and

294 ates that blood function and thus blood cell integrity were maintained throughout oxygenation.

295 f inflammation and blood-brain barrier (BBB) integrity were measured preoperatively and up to 48 hour

296 cibility of microbiome data depend on sample integrity, which can be affected by storage methods.

297 a critical regulator of DNA replication fork integrity, which, when compromised, may predispose to th

298 Desmosomes govern epidermal integrity while GJs facilitate small molecule transfer a

299 brain structure, function, and white matter integrity, with one of the subtypes showing poorer funct

300 ybe cells without compromising their overall integrity would be a very valuable tool to study functio