ライフサイエンスコーパス: intensification

1 or disease worsening necessitating treatment intensification.

2 ith climate change under higher agricultural intensification.

3 matological distribution of tropical cyclone intensification.

4 s that governments can follow for ecological intensification.

5 ion could be 10 times stronger than the mean intensification.

6 and negatively correlated with agricultural intensification.

7 ent-day fish communities respond to land use intensification.

8 he radius of maximum wind dictated the rapid intensification.

9 tes and identify sustainable pathways toward intensification.

10 hydraulic continuum, jointly affect drought intensification.

11 A, antibody negative) followed by 4-drug ART intensification.

12 decline is habitat loss due to agricultural intensification.

13 e complex than its association with headache intensification.

14 ding treatment duration or through treatment intensification.

15 on treated patients would require medication intensification.

16 atients at the highest risk to guide therapy intensification.

17 1 but with higher asparaginase levels during intensification.

18 s some of the drag that limits intensity and intensification.

19 and this will lead to an overall event-wise intensification.

20 [50 mg/m(2) x 3 days per cycle]) followed by intensification 1 (high-dose cytarabine and etoposide),

21 During intensification 1, the patient developed Streptococcus v

22 diogram was not repeated before the start of intensification 1.

23 tion 1 (high-dose cytarabine and etoposide), intensification 2 (high-dose cytarabine and mitoxantrone

24 On day 3 of intensification 2, the patient developed afebrile tachyp

25 F, 53%; SF, 27%), and she subsequently began intensification 2.

26 mg/m(2)/dose daily; four total doses]), and intensification 3 (high-dose cytarabine and l-asparagina

27 During medium-risk intensification, 50% had increased ALT and 3% hyperbilir

28 D] age, 66.4 [12.2] years), before treatment intensification, 51.5% used statin monotherapy and 1.7%

29 ive monitoring group had received adalimumab intensification (87%) compared with 24 patients in the r

30 After treatment intensification, 99.3% could achieve an LDL-C level of l

31 sponse-based risk stratification and therapy intensification abrogates the poor prognosis of adult ET

32 Most current research on land-use intensification addresses its potential to either threat

33 hesised to be associated with initiation and intensification: age, sex, deprivation, glycated haemogl

34 Ecological intensification aims to increase crop productivity by en

35 tion cohort) that applied stepwise treatment intensification algorithms in those with LDL-C levels of

36 ctive barrier of high VWS inhibits hurricane intensification along the U.S.

37 y a high-risk subgroup requiring therapeutic intensification among patients with locally advanced cer

38 A/B compartments, followed by their gradual intensification and expansion.

39 provide essential pollination services, but intensification and globalization of honey bee managemen

40 physiological traits directly affect drought intensification and indicate that inclusion of plant hyd

41 function similar to a warm ocean surface) on intensification and it's modulation by land cover change

42 De-intensification and personalisation of treatment to limi

43 listic picture of the impact of agricultural intensification and provides useful information when dec

44 largely threatened worldwide by agricultural intensification and rural areas abandonment processes re

45 Through further sustainable intensification and trade, reduced food waste and more p

46 es in recent decades, including agricultural intensification and urban expansion, as well as changes

47 nclusion of episodes of outpatient treatment intensification (and ED visits) in a composite outcome a

48 iversity at sites facing land-use change and intensification, and assess whether bee responses to the

49 such as soil sealing, agricultural land-use intensification, and biological invasions resulting from

50 ed much greater variability in their rate of intensification, and were much more likely to intensify

51 cs, where recent deforestation, agricultural intensification, and/or exports of land N storage can cr

52 medication intensification, antihypertensive intensification, antihypertensive class, carotid stenosi

53 emic intensification, cholesterol medication intensification, antihypertensive intensification, antih

54 To address this problem, we develop the Intensification approach, which uses the modular structu

55 lyses suggest that investments in ecological intensification approaches could potentially contribute

56 her more complex and uncertain components of intensification are also needed, i.e., increasing croppi

57 Our findings support ecological intensification as a solution to pollinator declines, an

58 The erosion of this natural intensification barrier is especially large following th

59 smatches in perceived benefits of ecological intensification between scientists and farmers, which hi

60 -scale ocean warming can lead to not only TC intensification but also TC expansion.

61 of the fuel for tropical cyclones and their intensification, but also provides some of the drag that

62 astal Alaskan precipitation and Aleutian Low intensification, but are of insufficient length to accur

63 Burst Intensification by Singularity Emitting Radiation (BISER

64 of the practices that constitute ecological intensification can contribute to mitigating the drivers

65 In streams, drought intensification can cross thresholds of habitat loss, wh

66 Land-use intensification can increase provisioning ecosystem serv

67 rent from zero, suggesting even conventional intensification can result in yield increases without co

68 These outcomes might guide treatment intensification choices.

69 in thrombosis prophylaxis, oral hypoglycemic intensification, cholesterol medication intensification,

70 ived a new classifier, Adjuvant Radiotherapy Intensification Classifier (ARTIC), comprising 27 genes

71 ministration, dose-dense consolidation, late intensification, CNS prophylaxis, and a 2-year maintenan

72 Hypertriglyceridemia occurred less in intensification compared with ALL-10 (37% v 47%), which

73 Further, metabolic intensification corroborated well with higher expression

74 Furthermore, the extreme intensification could be 10 times stronger than the mean

75 thotrexate, and prednisone (POMP), with four intensification courses (high-dose methotrexate plus L-a

76 ted in fewer patients reaching the treatment intensification criterion during 104 weeks versus IGlar

77 in the second induction cycle instead of the intensification cycle, and 1 of 4 daunorubicin-containin

78 Purpose Delayed intensification (DI) is an integral part of treatment of

79 The mass-transfer intensification does not increase monotonously with the

80 t that, in many cases, conventional land-use intensification drives a trade-off between species richn

81 Early rituximab intensification during R-CHOP-14 does not improve outcom

82 randomized trial assessed whether rituximab intensification during the first 4 cycles of R-CHOP coul

83 Poleward SWW intensification during the Late Holocene could then have

84 tural ecosystems while conventional land-use intensification (e.g. industrial management of large-sca

85 hough initially used primarily for treatment intensification following documented LQTS-associated bre

86 tions and electrochemically mediated process intensification for environmental remediation.

87 ts with GDMT medication initiations and dose intensifications from immediately preceding the cardiolo

88 office visit frequency, clinician treatment intensification given uncontrolled blood pressure, and c

89 of GO once during induction and once during intensification (GO arm, n = 408) as per the Children's

90 nt-pollinator networks along an agricultural intensification gradient to explore changes in network s

91 iming of undetectable MRD (after induction v intensification) had no impact on patient survival.

92 Agricultural landscape intensification has enabled food production to meet grow

93 Policies to promote ecological intensification have emerged in different countries, but

94 Growing populations and agricultural intensification have led to raised riverine nitrogen (N)

95 ime from randomisation to need for treatment intensification (HbA(1c) >=7.0% [53 mmol/mol] at two con

96 nt responses to soil properties and land use intensification; however, it is unclear whether this ext

97 re prescribed more ASNase because of therapy intensification (HR, 1.7; 95% CI, 1.1 to 2.7; P = .03).

98 uction regimens and treatment-to-target dose intensification improve outcomes.

99 vity, and achieving sustainable agricultural intensification in Latin America, requires policy interv

100 s raises numerous concerns and has led to an intensification in plastic monitoring and research.

101 We also identify seasonal intensification in rogue waves with increased rogue wave

102 oceanic environments unfavorable for typhoon intensification in SCS, which therefore serves as a natu

103 Primary outcomes were treatment intensification in the hypertension, diabetes, and chron

104 a decrease in salinity, which can lead to an intensification in the stratification of shallow nearsho

105 l patterns before and after the agricultural intensification, in the context of land-use change in ma

106 er 5-year EFS rate (88%, SE 2%) with therapy intensification (including 30 weeks of asparaginase expo

107 Previously, a time-dependent intensification (incubation) of cue-induced cocaine crav

108 Agricultural intensification is a leading cause of global biodiversit

109 re than 1200 wild plants, we ask if land use intensification is causing plant reproduction to be poll

110 e North American continent and Eurasia, this intensification is likely to involve overwhelming increa

111 sis of trends across Africa reveals that MCS intensification is limited to a narrow band south of the

112 This remote volcanic forcing-induced intensification is mainly through circulation change rat

113 If intensification is not successful and massive cropland l

114 ion systems and species groups, conventional intensification is successful in increasing yield (grand

115 hange, such as deforestation or agricultural intensification, is a key driver of biodiversity change.

116 obial composition; however, by allowing dose intensification, it dramatically improves irinotecan's e

117 scular magnetic resonance measures, diuretic intensification, Kansas City Cardiomyopathy Questionnair

118 Early treatment intensification leading to sustained good glycaemic cont

119 We found that agricultural intensification led to declines in modularity but increa

120 of the last deglaciation, and indicates this intensification led to increases in precipitation and in

121 uctivity and sustainability at two different intensification levels (average-yielding and high-yieldi

122 At both stages of treatment intensification, nonwhite groups had fewer HbA1c measure

123 Observations are complemented by intensification of absorbance peaks in FTIR spectra and

124 winter haze episodes in recent years due to intensification of aerosol pollution.

125 ising P fertiliser use is key to sustainable intensification of agricultural systems.

126 ronmental pollution are related to continued intensification of agriculture and super-shedder cattle.

127 a simplified representation of the potential intensification of agriculture based on expert elicitati

128 to ecosystem service delivery and ecological intensification of agriculture in the future.

129 Ecological intensification of agriculture represents a strategic al

130 plantings are promoted to foster ecological intensification of agriculture through provisioning of e

131 bout the environmental costs of conventional intensification of agriculture.

132 ng to precision N management for sustainable intensification of agriculture.

133 Advances in farming technology and intensification of animal agriculture increase the cost-

134 eral strategies to minimise thrombotic risk, intensification of anticoagulation, addition of an antip

135 women and men derive comparable benefit from intensification of antiplatelet therapy remains uncertai

136 The global intensification of antiretroviral therapy (ART) can lead

137 Intensification of antithrombotic therapy with more pote

138 gnificantly higher incidence of pathological intensification of anxiety as a constant trait.

139 These findings are consistent with an intensification of AR predicted by future projections.

140 re transport due to, among other factors, an intensification of atmospheric rivers (ARs) activity, wh

141 ork, we propose a possible mechanism for the intensification of aversive feelings after withdrawal th

142 Rescue medication, defined as intensification of background antidiabetic treatment or

143 This methodology also enables the intensification of biocatalysis as demonstrated in high

144 oss in the capsulated mixed infection and to intensification of bone loss in the non-capsulated mixed

145 (cardiovascular) mortality calls for further intensification of cardiovascular risk management, and a

146 eather events is applied to the 21st-century intensification of Central Pacific trade winds, emergenc

147 The intensification of color was correlated with the E. coli

148 Despite intensification of control efforts, MiP remains high at

149 % and overall emissions by 2.5% showing that intensification of dairy in a low-income country can inc

150 nitiatives to improve timely and appropriate intensification of diabetes treatment are key to reducin

151 Ethnic differences in time to initiation and intensification of diabetes treatment were estimated at

152 patients in the empagliflozin group reported intensification of diuretics (297 versus 414 [HR, 0.67;

153 Such improved performance is attributed to intensification of dominant microbial population in sepa

154 ing caused by CO2 rise generally suggest the intensification of dry conditions over these subtropical

155 Our study indicates that an intensification of ENSO will have negative effects on so

156 Rapid intensification of environmental disturbances has sparke

157 tegies: off-setting natural habitats through intensification of existing farmland (land sparing), or

158 Climate change is generating an intensification of extreme environmental conditions, inc

159 regions would expand given the human-induced intensification of flash drought risk.

160 isruption and native population decline, and intensification of forest use during the later 19th cent

161 In contrast, potential intensification of future El Nino events could negativel

162 a cardiology clinic visit improved clinician intensification of GDMT.

163 ferences in the timeliness of initiation and intensification of glucose-lowering therapy in individua

164 Timely and appropriate initiation and intensification of glucose-lowering therapy is key to re

165 had an ED visit without previous outpatient intensification of HF therapy or a subsequent event with

166 , 361 of 8399 patients (4.3%) had outpatient intensification of HF therapy without a subsequent event

167 over the past century is attributable to the intensification of human activities.

168 how that positive skew reduces with temporal intensification of human impacts in the lake and surroun

169 h the early Miocene onset and middle Miocene intensification of hyperarid conditions along the centra

170 ogical basis to expect temperature-dependent intensification of impacts on hosts.

171 Intensification of in-clinic/remote evaluations and invo

172 t crop, supporting optimization of yield via intensification of insect pollination, and highlights th

173 poral trends demonstrated that the onset and intensification of lacustrine hypoxia were more strongly

174 Urbanization and agricultural intensification of landscapes are important drivers of g

175 Growing evidence suggests that ecological intensification of mainstream farming can safeguard food

176 ional capabilities, predicting intensity and intensification of major tropical cyclones remains a cha

177 surface magnetic field is twisted; and (iii) intensification of Maxwell stresses in the corona above

178 cally Delivered, Patient-Activation Tool for Intensification of Medications for Chronic Heart Failure

179 We find that the intensification of metallic layered phenomena above thun

180 ing stratification of the Southern Ocean and intensification of mid-latitude westerly winds today, su

181 Despite an intensification of NAO- events, reflected by more preval

182 l phase is observed followed by a subsequent intensification of neutral Na number density with an inc

183 Further intensification of nonspecific therapy is unlikely to of

184 The intensification of Northern Hemisphere Glaciation is the

185 sumes no LLT intolerance and full adherence, intensification of oral LLT could achieve an LDL-C level

186 Sustainable intensification of pasture is most promising for local d

187 Intensification of platinum agents in the S2 and S3 tria

188 d for wholesome and nutritious food leads to intensification of production, which in turn can have a

189 Intensification of rainfall cycles, ranging from frequen

190 This study assessed how the intensification of RI helped strengthen service delivery

191 -14 with (RR-CHOP-14) or without (R-CHOP-14) intensification of rituximab in the first 4 cycles.

192 The remarkably rapid intensification of Sahelian MCSs since the 1980s sheds n

193 reased vertical shear is consistent with the intensification of shear-driven clear-air turbulence exp

194 Intensification of SOF treatment with LDV reduced the em

195 rventions and consideration of initiation or intensification of statin therapy for primary prevention

196 imate change: acidification, sea-level rise, intensification of storms, shifts in species distributio

197 We estimate that intensification of the 8-12% of global croplands overlyi

198 opening of the Drake Passage and associated intensification of the Antarctic Circumpolar Current (AC

199 kely driven jointly by mountain building and intensification of the Asian monsoon.

200 pite most forest plots having experienced an intensification of the dry season.

201 t evidence indicates that climate change and intensification of the El Nino Southern Oscillation (ENS

202 Intensification of the global hydrological cycle, rangin

203 ed likelihood of extreme rainfall events and intensification of the hydrologic cycle.

204 Ongoing intensification of the hydrological cycle is altering ra

205 Our record is consistent with intensification of the Pacific winter storm track in res

206 The intensification of the poultry industry in the last deca

207 The intensification of the process in a continuous-flow reac

208 This was amplified by the intensification of the snow accumulation (+50% at Dasuop

209 e uncertainties by 45% and indicate a robust intensification of the WNPSH due to suppressed warming i

210 The intensification of the WNPSH implies more future monsoon

211 in the control experienced an initiation or intensification of their GDMT (P=0.001).

212 Despite progress in intensification of therapy, outcomes for patients with m

213 sk of early mortality is a priority to guide intensification of therapy.

214 computer models were unable to predict rapid intensification of these storms.

215 Here we show that the simplification and intensification of these systems and their growing conne

216 ture is an important factor facilitating the intensification of these, and likely other, HABs and thu

217 in dosing intervals may be a consequence of intensification of treatment due to year-on-year VA loss

218 and sea-level rise will lead to significant intensification of trematode parasitism, suppressed fecu

219 higher dosage of PEG-asparaginase and early intensification of triple intrathecal therapy would impr

220 t converting them into open water can impede intensification of tropical systems that affect the area

221 r ecosystem service schemes, and sustainable intensification of under-yielding farmland, as well as g

222 increasingly restricted by the expansion and intensification of urban and agricultural lands.

223 Impact of the "Intensification of Vaporization by Decompression to the

224 research areas to accelerate the sustainable intensification of vertical farming using aeroponic syst

225 or Neoproterozoic 'greening of the land' and intensification of weathering c. 0.85-0.54 Ga is current

226 Our results suggest that two independent intensifications of the East Asian summer monsoon (EASM)

227 Land-use intensification on arable land is expanding and posing a

228 e is known about the simultaneous effects of intensification on biodiversity and yield.

229 ctive effects of climate change and land-use intensification on body size, density, and biomass of so

230 e the strong negative effect of agricultural intensification on pintail productivity across nearly al

231 The contribution of agricultural intensification on the deceleration of SCA at MLO was el

232 e required to identify promising sustainable intensification options in high-yielding cereal systems.

233 pray, with consequences for tropical cyclone intensification or decline, particularly in areas of alg

234 ients in the IDegLira group needed treatment intensification over 104 weeks than those in the IGlar U

235 displaying substantial climate change-driven intensification over the last century.

236 ative of patients eligible for basal insulin intensification (overall mean diabetes duration 10 years

237 including 2 interim maintenance and delayed intensification phases.

238 survival and overall survival, assessed from intensification randomisation to data cutoff, analysed b

239 28, 2016, 583 patients were enrolled to the intensification randomisation, representing 48% of the 1

240 ature (1-week return visit interval, 20%-44% intensification rate, and 76% adherence rate).

241 ow significant increases in tropical cyclone intensification rates in the Atlantic basin that are hig

242 Increasing treatment intensification rates to 62% of office visits with an un

243 ts suggest a detectable increase of Atlantic intensification rates with a positive contribution from

244 e observed upward trends in tropical cyclone intensification rates.

245 nce may become more probable as agricultural intensification reduces the availability of refuges and

246 evaluated prior to considering treatment de-intensification regimens for HPV-associated oropharyngea

247 changes following heart failure (HF) therapy intensification relative to the goal NT-proBNP value of

248 all approaches for upconversion luminescence intensification require stringent controls over numerous

249 We make available the Intensification results as an online resource and illust

250 ions of LDL-C levels under various treatment intensification scenarios.

251 Therefore, intensification should produce more food while reducing

252 erests in chemical manufacturing and process intensification, simple, inexpensive, and reliable ceram

253 he Intertropical Convergence Zone (ITCZ) and intensification/slowdown of Walker circulation.

254 Treatment intensification, step-up in hospital care, and mortality

255 n atorvastatin, 20 mg, and the following LLT intensification steps were applied: uptitration to atorv

256 For example, small intensification steps within low intensity systems did n

257 Treatment intensification strategies with LLT.

258 y the implementation of early response-based intensification strategies.

259 Ecological intensification such as organic farming and cover croppi

260 olume index, LV ejection fraction), diuretic intensification, symptoms (Kansas City Cardiomyopathy Qu

261 Conclusion: When considering treatment intensification, the currently used Deauville score cuto

262 driven these advances including asparaginase intensification, the use of induction dexamethasone, and

263 ted of 4 cycles of induction and 2 cycles of intensification therapy based on the treatment schema of

264 Process intensification through continuous flow reactions has in

265 PALN involvement, thus allowing therapeutic intensification to be proposed.

266 77.4% for standard ABVD + INRT to 90.6% for intensification to BEACOPPesc + INRT (hazard ratio [HR],

267 Intensification to insulin therapy was slower again for

268 ation to noninsulin combination therapy, and intensification to insulin therapy) using multivariable

269 oints (initiation of noninsulin monotherapy, intensification to noninsulin combination therapy, and i

270 tion by transplantation eligibility status); intensification treatment (allocation by response to ind

271 ortezomib, and dexamethasone (CVD) versus no intensification treatment in patients with newly diagnos

272 Intensification treatment with CVD significantly improve

273 We aimed to assess response-adapted intensification treatment with cyclophosphamide, bortezo

274 n, and stratified by allocated induction and intensification treatment, and centre.

275 misations in the study: induction treatment, intensification treatment, and maintenance treatment.

276 odulatory induction therapy compared with no intensification treatment, but did not improve overall s

277 For the intensification treatment, patients were randomly assign

278 e report the results of the randomisation to intensification treatment.

279 ically needed given the expected disturbance intensification under a warming climate.

280 Paclitaxel dose intensification was achieved with weekly treatment (medi

281 Intensification was defined by the addition of a new ant

282 eraction between pond count and agricultural intensification was insufficient to overcome the strong

283 Dose intensification was needed in 29.5% of the patients.

284 ra group had significantly longer time until intensification was needed than those in the IGlar U100

285 T1-weighted MRI signal intensification was not observed.

286 f species richness and yield to conventional intensification, we conducted a global meta-analysis syn

287 of monsoon cycles correspond closely to the intensification/weakening of human activity and the flou

288 As responses to drought intensification were both linear and nonlinear, generali

289 ADA development, low TL and need for dose intensification were frequent during adalimumab therapy

290 Agricultural expansion and intensification were primary drivers of declining fire a

291 increases in cropland area and agricultural intensification will likely impact vast portions of Asia

292 model large ensemble experiments, event-wise intensification will significantly increase globally for

293 iling appear to benefit from early treatment intensification with autologous transplantation, as indi

294 Intensification with insulin had the greatest risk of mo

295 come of patients with metastatic RMS by dose intensification with interval compression, use of the mo

296 Intensification with noninsulin combination therapy was

297 ith TF defined as the composite of treatment intensification with systemic corticosteroids and/or ant

298 However, treatment effects of intensification with the medications on the risk of seve

299 Conventional intensification within medium intensity systems revealed

300 refer to a type of droughts that have rapid intensification without sufficient early warning.