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1 nine kinase [8], as a putative novel anillin interactor.
2 L3MBTL3 (also known as MBT1) as a novel RBPJ interactor.
3 oprocessor component DROSHA as a novel DNMT1-interactor.
4 d DNA (ssDNA)-binding protein, as a novel G4 interactor.
5 th SR34 as bait and discovered SR45 as a new interactor.
6 ly receptor transmembrane activator and CAML interactor.
7 found that U1 snRNP is the most abundant FUS interactor.
8 atty acid (VLCFA) synthesis pathway and core interactor.
9 mass spectrometry to identify BIRC3 protein interactors.
10 ction of RPGR isoforms with their endogenous interactors.
11 subsequently validated many putative zDHHC17 interactors.
12 roteins, here we sought to identify new PP1c interactors.
13 sically linked to each other in vivo are LBC interactors.
14 y to the nucleus when coexpressed with these interactors.
15 ating RNAPII, while P-TEFb was not among the interactors.
16 affimer" reagents as high-affinity ubiquitin interactors.
17 independent experiments, to filter bona fide interactors.
18 ctions of PLEKHA7, we looked for new PLEKHA7 interactors.
19 echanism for bringing together their diverse interactors.
20 A target, with relevance to other TPR domain interactors.
21 cribed PPIs as well as to identify novel NS1 interactors.
22 G-protein signaling components and G-protein interactors.
23 complex with cullin 3 (CUL3), are novel IRS1 interactors.
24 vel function of Shank3 in recruiting Abelson interactor 1 (ABI1) and the WAVE complex to the post-syn
25 ing G protein-coupled receptor (GPCR) kinase interactor 1 (GIT1), which we found to play an unexpecte
26 or HAI1-interacting proteins identified HAI1-Interactor 1 (HIN1), a nuclear protein of unknown functi
27 identified mitofusin2 (MFN2) and Rab and Ras Interactor 1 (RIN1) as new Smad2 binding partners requir
30 protein 4)/TRIP10 (thyroid hormone receptor interactor 10) was identified as a new polyproline domai
31 anonical synaptic vesicle SNAREs Vps10p-tail-interactor-1a (vti1a) and vesicle-associated membrane pr
34 tantly, we determined that a subset of these interactors also modified hLRRK2(I2020T) induced dopamin
36 a tomato UspA, is, to our knowledge, a novel interactor and phosphorylation target of a member of the
37 re mimicked by downregulation of OSBP, a VAP interactor and PI4P transporter that participates in VAP
39 nctionally specific role of PFN2 as a stable interactor and regulator of the actin N-terminal acetylt
40 -S100A10 protein complex as a novel Munc13-4 interactor and show that AnxA2-S100A10 participates in r
41 ts, we identified C19ORF57/BRME1 as a strong interactor and stabilizer of HSF2BP and showed that the
43 tified several proteins including known BAK1 interactors and a previously uncharacterized LRR-RLP tha
45 f G-protein signaling (RGS) proteins are key interactors and critical modulators of the Galpha protei
46 sought to identify additional WW domain host interactors and demonstrate that the PPxY L domain motif
48 ckdowns of sixteen previously identified Tat interactors and found that a novel E3 ligase, PJA2, ubiq
51 rtin-like kinase 1 and 2 as bona fide KLHL15 interactors and mapped KLHL15 interaction regions to the
52 identified VCS and VARICOSE RELATED (VCR) as interactors and phosphorylation targets of SnRK2.5, SnRK
53 ge analysis revealed that although some HP1a interactors and regulators are broadly distributed withi
54 ority of the over four hundred putative HP1a interactors and regulators identified were previously un
55 performed a proteomic screen for novel HEG1 interactors and report that HEG1 binds directly to Rasip
56 conserved repression motifs present on REL2 interactors and showed that two of these, RLFGV- and DLN
57 oID provides a tool for identifying new mRNA interactors and studying the dynamic view of the interac
58 major differences in their autophagy-related interactors and their post-translational and transcripti
59 e are no methods to accurately predict Hsp90 interactors and there has been considerable network rewi
60 ACTOR) transcription factor family are DELLA interactors and, at the same time, that several GRF gene
61 E, to populate the network of its functional interactors and, in doing so, to uncover new cancer-asso
62 s, identified as a zDHHC20 S-acyltransferase interactor, and annotated as a potential thioesterase.
63 rane activator and calcium modulating ligand interactor, and B cell maturation antigen, at a stoichio
64 Ag (BCMA), transmembrane activator and CAML interactor, and BAFF receptor, in sorted human immune ce
65 GB1 is a huntingtin N17/PY-NLS ROS-dependent interactor, and this protein bridging is essential for r
66 ceptor-associated factor 6 (TRAF6) as a SOD1 interactor, and we determined that exposure of the SOD1
67 cription, longer canonical transcripts, more interactors, and a higher number and more types of post-
68 on, we purified Drosophila melanogaster HP1a interactors, and performed a genome-wide RNAi screen to
69 ion vector to allow paired-end sequencing of interactors, and the use of protein fragments rather tha
72 ns) cells, the overwhelming majority of EBP1 interactors are part of ribonucleoprotein complexes regu
74 identified a specific role for ATL3, and its interactor ARF4, in vesicle trafficking and virion matur
76 ork are discussed, with the most significant interactors being responses to hypoxia, regulation of ce
77 ence) of hnf4 and its predicted gene pathway interactors beta-catenin and hh Interestingly, the model
78 the affinity of RAB11B to a series of binary interactors, both effectors and guanine nucleotide excha
80 ort, we identified additional host WW-domain interactors by screening for potential interactions betw
81 , providing high-certainty identification of interactors by their direct access during cycling infect
85 , we show that Dyrk2 kinase, a reported UBR5 interactor, cooperates with UBR5 in mediating MOAP-1 ubi
86 the interaction between carboxyltransferase interactors (CTIs) and alpha-CT, which in turn attenuate
90 Our results demonstrate that NFS1 and its interactor FH are involved not only in nonhost resistanc
91 sues and reproducibly retrieved at least one interactor for 81.4 % of the baits screened for in callu
93 ctrometry to map the glycan and glycoprotein interactors for galectin-3 in live human hepatic stellat
94 y, our TAP protocol enables the discovery of interactors for low abundance proteins in rice and opens
95 roposed as a therapeutic strategy, druggable interactors for rescue of ATP7B mutants remain elusive.
97 the NITROGEN FIXATION S-LIKE1 (NFS1) and its interactor FRATAXIN (FH), when silenced in Nicotiana ben
99 c protein partners were identified, with the interactors functioning mainly in DNA maintenance and mi
103 x protein CHD4, and the repressive chromatin interactor HP1BP3, by co-immunoprecipitation combined wi
104 es, we further focused on bona fide ribosome interactors (i.e. SEC61) and ER proteins (ribophorin I,
106 predicted components and identify additional interactors implicated in histone acetylation and chroma
112 ity to detect proximal proteins and putative interactors in intact tissues, and to quantify changes c
114 tools for the discovery of Ub chain-specific interactors in proteomic studies, but their structural d
116 ealed several TCR adaptor proteins acting as interactors in stimulated cells, of which LAT and Trat1
123 others have previously identified novel eNOS interactors, including G protein-coupled receptor (GPCR)
124 tively charged motif in a subset of PP2A:B56 interactors, including KIF4A, to facilitate B56 binding
125 otif determinants uncovered unanticipated CN interactors, including NOTCH1, which we establish as a C
126 nt (MT) H-, K-, and N-Ras, identifying known interactors, including Raf and PI3K, as well as a common
127 pectrometry (MS), we identified several eNOS interactors, including the protein plasminogen activator
128 on screen identified numerous potential host interactors, including the Rho GTPases Rac1 and Cdc42.
131 of DOPr and revealed several endogenous DOPr interactors involved in protein folding, trafficking, an
132 thus able to discover a number of novel Rif1 interactors, involved in chromatin metabolism and phosph
135 A list of non-specific and false positive interactors is presented, based on re-occurrence over mo
136 As these small, globular proteins have many interactors, it has been difficult to ensure that method
137 identified a novel and functional EBOV VP40 interactor, ITCH, that regulates VP40-mediated egress.
138 aging, we identified the Kif1B motor and its interactor Kif1 binding protein (KBP) as critical for SC
139 ases, we also examined ATP1A3 and all of its interactors known to be expressed in the brain to establ
141 By mass spectrometry, we detected a RIT1 interactor, leucine zipper-like transcription regulator
142 and identity of component species, as strong interactors like foundation species have the potential t
147 e possibility that targeting NRP1 or its NCD interactors may be a useful therapeutic strategy in neov
148 ural response appeared not influenced in the interactor mutants katA and acnB in steady-state behavio
150 Es) directing their wiring within the "ncRNA interactor networks" through the emergence of secondary
153 ALG-2 interacting protein X (Alix/AIP1), an interactor of apoptosis-linked gene protein 2 (ALG-2).
155 identify a protein named TSSC1 as a specific interactor of both GARP and EARP and as a novel componen
156 at ROP INTERACTIVE PARTNER b (RIPb; synonym: INTERACTOR OF CONSTITUTIVE ACTIVE ROP b) directly intera
161 Subsequently, we identified Sp110 as a novel interactor of HBx and found this association to be essen
166 vealed that FRS7 and FRS12 recruit the NOVEL INTERACTOR OF JAZ (NINJA) to assemble a transcriptional
168 at NS5A protein represents the most probable interactor of M3R or that this viral protein could elici
169 ults altogether demonstrate that LCBK1 is an interactor of MEA that positively regulates PTI-induced
171 dentifies mitochondrial protein ATAD3A as an interactor of mitochondrial fission GTPase, Drp1, in HD.
174 posed natural ligand, CXXC repeat-containing interactor of PDZ3 domain (CRIPT), and results from prev
175 main-containing protein 11 (PDZD11) as a new interactor of PLEKHA7 by yeast two-hybrid screening and
176 ent, PROLINE-TRYPTOPHANE-TRYPTOPHANE-PROLINE INTERACTOR OF POLYCOMBS1, in Arabidopsis (Arabidopsis th
177 dentified cortactin as a novel substrate and interactor of proline-rich tyrosine kinase 2 (Pyk2).
181 on experiments established DGCR8 as a direct interactor of Tcf7l1 mRNA, a core component of the pluri
184 ly, we identify the small GTPase RAB11 as an interactor of the guanine nucleotide exchange factor DEF
185 h-mobility group box 1 (HMGB1) protein as an interactor of the intervening sequence within the PY-NLS
186 a2+-dependent modulator of ICR1 (CMI1) as an interactor of the Rho of plants (ROP) effector interacto
187 alling and identify Axin1 as a novel protein interactor of the widely-expressed gamma-Pcdh-C3 isoform
188 like (Mid1ip1l), previously identified as an interactor of the X-linked Opitz G/BBB syndrome gene pro
190 vered the leucine-zipper protein LUZP1 as an interactor of truncated SALL1, a dominantly-acting prote
193 Green Fluorescent Protein (GFP) to identify interactors of a GFP-tagged protein of interest by high-
194 mass spectrometry analysis for brain-derived interactors of ArPIKfyve-Sac3 and unraveled the alpha-sy
195 mass spectrometry analysis to detect in vivo interactors of AtGET1 and identified a membrane protein
197 mplementary screens for genetic and physical interactors of BRD4, which converge on the folate pathwa
199 ggest that IQGAP proteins are not functional interactors of H-, K-, or N-Ras and challenge the ration
200 mary tissue as well as the identification of interactors of insoluble proteins that form higher-order
201 wo-hybrid assay, we discovered several novel interactors of MAFR-1 that are expressed in a sperm- and
202 therapeutic targets, we searched for unique interactors of mTOR complexes through proteomics analyse
203 Functional analyses of meiosis-specific interactors of MutLgamma-Exo1 identified Rtk1, Caf120, a
206 hermore, transposon mutagenesis of oxa-23 or interactors of Oxa-23 demonstrates changes in meropenem
210 finity-purification and mass spectrometry of interactors of the centrosomal and ciliopathy protein, C
214 pressed genes showed enrichment for putative interactors of the first three identified COPD GWAS gene
215 e KHD1 and SPEN3 proteins were identified as interactors of the HUB1 and HUB2 proteins with in vitro
216 e tool to reconstruct networks and query for interactors of the kinetochore complex as well as conser
219 we found differential expression of putative interactors of these genes, and we replicated previous h
220 domain-containing proteins and ALKBH5, known interactors of this modification, we find that FMR1 and
221 s identified with FAMA-TurboID include known interactors of this stomatal transcription factor and no
225 xpressing AMLs, that Hoxa genes and selected interactors or downstream targets are required for survi
227 ckers and/or SE-lockers that will change the interactor partners' spectrum of proteins, RNAs, DNAs, o
229 -3 (RGA) inhibits RGA binding to four of its interactors-PHYTOCHROME-INTERACTING FACTOR3 (PIF3), PIF4
230 h diverse proteins, and its most predominant interactors play important roles in postsynaptic recepto
231 oteins are epigenetic repressors and lamin A interactors, primarily involved in the maintenance of ce
232 terminal beta-strand shapes the broader ATG8 interactor profiles, defining interaction specificity wi
234 ly the second structure of a 14-3-3 mode III interactor, provides further insight into this less-well
236 ed that caveolin 1 (CAV1), a well-known eNOS interactor, regulates eNOS activity in sinusoidal endoth
237 mutants did not depend on the SHR functional interactor SCARECROW and the sugar signaling component A
239 alysis of Arabidopsis homologs of BjNRAMP4.1 interactors showed enrichment of many protein components
240 F-dependent transmembrane activator and CAML interactor signals in atherosclerosis pathogenesis, of p
241 s spectrometric identification of the OTULIN interactor SNX27 (sorting nexin 27), an adaptor of the e
244 ding the transcriptional repressor and MeCP2 interactor switch-insensitive 3 family member A (SIN3A;
246 gen (BCMA), transmembrane activator and CAML interactor (TACI) but not to the BAFF receptor (BAFFR).
247 How mutant transmembrane activator and CAML interactor (TACI) influences wild-type TACI function is
248 brane activator and calcium modulator ligand interactor (TACI) is important for T-independent antibod
250 ro of CD86, transmembrane activator and CAML interactor (TACI), and CD23 activation markers after TLR
253 unconventional prefoldin, RNA polymerase II interactor that functions as a transcriptional repressor
254 calpain 1 (CAPN1) as an exclusive rPhe508del interactor that prevents active EZR recruitment, impairs
256 volved in known BIRC3 functions, we detected interactors that bind only to BIRC3 protein encoded from
259 e of which are potential stage-specific mRNA interactors that likely reflect the dynamics of RNA-prot
261 es, we identified novel high-confidence CTCF interactors that provide a still unexplored biochemical
262 viability, we uncovered a novel role for its interactor, the ESCRT-I protein TSG101: it directly part
264 velopment to this technique, allowing CENP-A interactors to be characterized within only a few minute
265 oinformatic analysis linked ER-E3s and their interactors to multiple homeostatic, regulatory, and met
267 P, we sought to identify direct IRF6 protein interactors using a combination of yeast 2-hybrid screen
269 tome of PAX3-FOXO1 and screened 60 candidate interactors using siRNA-mediated depletion to identify c
270 AF patients, with CSDA and PDE5A being novel interactors validated by bioinformatics, immunocytochemi
272 ins, including several highly specific ACTN4 interactors, was globally decreased in the patient-deriv
277 From a screen for functionally relevant ERG interactors, we identify the arginine methyltransferase
278 modules consisting of driver genes and their interactors, we show that these interactions are associa
283 ore proteins ABC1K3, PES1, and CCD4 as PGM48 interactors, whereas several other PG-localized proteins
284 structure of a complex containing a mode III interactor, which is defined as a 14-3-3 interaction wit
285 pathway and cell adhesion molecule, as a CK5 interactor, which we confirmed by co-immunoprecipitation
286 howed that H2A.Z.1 and H2A.Z.2 have specific interactors, which can mediate their functional antagoni
287 rification allowed copurifying PSBS with its interactors, which were identified by mass spectrometry
290 g protein DJ-1 and non-muscle myosins as Tau interactors whose binding to Tau was profoundly influenc
291 g approaches, we demonstrate that the N-WASP-interactors WIP and WICH/WIRE play non-redundant roles i
292 analysis identified annexinA2 as a potential interactor with the extracellular domains of PLA2R.
293 ting Protein 1 (Cnrip1) was discovered as an interactor with the intracellular region of Cannabinoid
294 ow that Scribble PDZ1 and PDZ3 are the major interactors with beta-PIX and reveal a distinct binding
295 lated protein (Hip1R) are mutually exclusive interactors with CLCa, and suggest a model for the seque
296 and cyclophilin, were found to be consistent interactors with G(N) These newly discovered thrips prot
298 d 69 negative and 82 positive common genetic interactors, with functions related to cellular growth a
300 DGFRA), as well as novel RNA-binding protein interactors ZC3H14 (zinc finger CCCH-type containing 14)