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1 y, an antiparallel microtubule bundle at the intercellular bridge.
2 e germline founder cell and to stabilize the intercellular bridge.
3 ession, resulting in the formation of a thin intercellular bridge.
4 that arise from high membrane tension at the intercellular bridge.
5 o the midbody and direct the severing of the intercellular bridge.
6 scission until chromatin is cleared from the intercellular bridge.
7 roposed to attach the cleavage furrow to the intercellular bridge.
8 body structure, located at the center of the intercellular bridge.
9 r abscission to an integral component of the intercellular bridge.
10 e of the midbody matrix in the middle of the intercellular bridge.
11 nd keeps the daughter cells connected via an intercellular bridge.
12 into separate cells or formation of a stable intercellular bridge.
13 rce subsequently mediates cytofission of the intercellular bridge.
14 ase, staining shifted to the midbody and the intercellular bridge.
15 ), which pass products to the oocyte through intercellular bridges.
16 identifying molecular mechanisms regulating intercellular bridges.
17 anillin and non-muscle myosin II (NMM-II) to intercellular bridges.
18 erring stability and elasticity to germ cell intercellular bridges.
19 to a shared cytoplasm core (the rachis) via intercellular bridges.
20 gether to prevent abscission and form stable intercellular bridges.
21 ls that are interconnected by TEX14-positive intercellular bridges.
22 a novel protein that localizes to germ cell intercellular bridges.
23 whereby cells remain interconnected by long intercellular bridges.
24 d throughout the group by spread through the intercellular bridges.
25 regulatory molecules cannot occur via these intercellular bridges.
27 subsequently nucleate the assembly of stable intercellular bridges,(15)(,)(16)(,)(17)(,)(18) structur
28 resulting in a cluster of cells connected by intercellular bridges.(6)(,)(7)(,)(8)(,)(9)(,)(10) In ad
29 chinery that promotes the degradation of the intercellular bridge, a transient protein structure conn
30 s are held together by a combination of fine intercellular bridges, a shared extracellular matrix, an
31 asma membrane at the cleavage furrow and the intercellular bridge, accompanied by a depletion and unf
32 Germ cells in most animals are connected by intercellular bridges, actin-based rings that form stabl
33 nillin RNAi caused gradual disruption of the intercellular bridge after furrowing; citron-kinase RNAi
34 e we utilized a Tex14 hypomorph with reduced intercellular bridges along with Tex14-null mice that co
35 al properties have been shown to localize to intercellular bridges (also called midbody) connecting t
36 rovides both structural support for a narrow intercellular bridge and a platform that orchestrates th
38 that CEP55 becomes a stable component of the intercellular bridge and that an evolutionarily conserve
39 nd ANI-2 loss resulted in destabilization of intercellular bridges and germ cell multinucleation defe
40 abscission leading to the formation of long intercellular bridges and multinucleated cells, which mi
41 ve information about the morphology of these intercellular bridges and the extent of their distributi
42 apoptosis during cytokinesis with unresolved intercellular bridges, and rescue experiments show that
45 Although these findings demonstrate that intercellular bridges are essential for spermatogenesis,
49 force propels the fission complex along the intercellular bridge away from the midbody until it reac
50 ial core of the Stan system is an asymmetric intercellular bridge between Stan in one cell and Stan a
51 The midbody is an organelle assembled at the intercellular bridge between the two daughter cells at t
52 es not complete abscission, leaving a stable intercellular bridge between the two daughter cells.
55 llenge, particularly given the complexity of intercellular bridging between T cells and tumor cells.
56 rst 52 amino acids (CHMP6-N), arrives at the intercellular bridge, blocks abscission, and subsequentl
57 N does not interfere with its arrival at the intercellular bridge but almost completely abolishes the
58 show that LZTS2 enriches not only at midbody/intercellular bridges but also at apical adhering juncti
59 itosis, centralspindlin is maintained at the intercellular bridge by anillin, and CYK-4 is localized
60 ms an arrested cleavage furrow into a stable intercellular bridge by the addition of several proteins
65 during germ cell division to produce stable intercellular bridges, called "ring canals," is poorly u
66 hile mitosis is completed within 15 min, the intercellular bridge can persist for hours, maintaining
70 germ cell cytokinesis results in a permanent intercellular bridge connecting the daughter cells throu
71 cellular communication facilitated by stable intercellular bridges connecting developing germ cells.
72 chemoreceptor arrays, and that they can form intercellular bridges connecting two to three cells with
73 e cytokinesis, a network forms in which each intercellular bridge corresponds to a past mitotic event
75 of CaBP7 with lysosomes that cluster at the intercellular bridge during cytokinesis in HeLa cells.
76 ed the spatiotemporal characteristics of the intercellular bridge during early zebrafish development.
77 es required to maintain RhoA activity at the intercellular bridge during late cytokinesis and thus fa
78 is fundamental for development, the role of intercellular bridges during embryogenesis has not been
80 nuation in Tex14 hypomorphs, indicating that intercellular bridges enable cytoplasmic exchange betwee
81 to other germ cell proteins to form a stable intercellular bridge essential for male reproduction.
82 e of Drosophila melanogaster is required for intercellular bridge formation during cytokinesis in mal
83 o proteins essential for mammalian germ cell intercellular bridge formation have been identified.
84 to the conceptus through persistence of the intercellular bridge formed during its abstriction, and
85 sequentially recruited to the center of the intercellular bridge, forming a series of cortical rings
86 family scaffold protein ANI-2 is enriched at intercellular bridges from the onset of germ cell specif
87 vity exhibit two distinct defects: disrupted intercellular bridges (fusomes) and premature centriole
88 report that in males deficient for TEX14 and intercellular bridges, germ cells fail to complete meiot
89 ntial components of the vertebrate germ cell intercellular bridge have until now not been described.
91 t signal of TEX14, an essential component of intercellular bridges (ICB) between developing germ cell
95 mutation at T(1847) had significantly longer intercellular bridges, implying that Aurora-B-mediated p
96 es to the spindle midzone and the subsequent intercellular bridge in mammalian cells and is also enri
97 zation and function at a stable, postmitotic intercellular bridge in the Caenorhabditis elegans gonad
98 own that targeted deletion of TEX14 disrupts intercellular bridges in all germ cells and causes male
99 lts, negative regulators of NMM-II stabilize intercellular bridges in the Drosophila egg chamber [10,
100 find that mouse germ cells are connected by intercellular bridges in the ovaries of 11.5 to 17.5 day
102 ring spermatogenesis, proposed roles for the intercellular bridge include germ cell communication, sy
103 n-cell-intrinsic and inform a model in which intercellular bridges influence critical meiotic events
104 sis concludes with the formation of a stable intercellular bridge interconnecting daughter cells in a
105 and these studies provide evidence that the intercellular bridge is essential for spermatogenesis an
106 We have shown that the stability of the intercellular bridge is essential for successful cytokin
108 duces lysosome mislocalization, extension of intercellular bridge lifetime, and cytokinesis failure.
111 SCRT-III subunits constrict membranes of the intercellular bridge midbody to the abscission point.
113 ing body and thinning of microtubules in the intercellular bridge of cells depleted of LARG is consis
114 with each other during gametogenesis through intercellular bridges, often called ring canals (RCs), t
116 y, which drives abscission, were enriched at intercellular bridges post-MBT and, interfering with ESC
117 s isolated, coincident with formation of the intercellular bridge; proper progression through this st
120 M-3, a known binding partner [9], to promote intercellular bridge stability and limit localization of
122 that germ cells die as clones independent of intercellular bridges, suggesting that shared intrinsic
123 t with the localization of NMHC II-C1 to the intercellular bridge that attaches the two dividing cell
124 We show that each PGC possesses a stable intercellular bridge that connects it to a common pool o
125 stem body, a structure in the middle of the intercellular bridge that forms between two dividing cel
126 ncytium in which each germ cell possesses an intercellular bridge that is maintained by a stable acto
127 mmunication is facilitated by plasmodesmata: intercellular bridges that allow the direct (cytoplasm-t
128 conserved mechanism for the stabilization of intercellular bridges that can occur by diverse molecula
129 Instead, daughter cells remain connected by intercellular bridges that contain bundled microtubules
130 served groups of oogonial cells connected by intercellular bridges that develop as nurse cells as wel
131 blast) to generate sister cells connected by intercellular bridges that facilitate the exchange of ma
132 ntain the compacted microtubule state at the intercellular bridge, thereby dampening acetylation.
133 the extent and distribution of follicle cell intercellular bridges to be confined to arrays of no mor
135 Using TEX14 as a marker for the germ cell intercellular bridge, we show that TEX14 co-localizes wi
136 g a biochemical enrichment of male germ cell intercellular bridges, we identified additional bridge p
137 t tension contributes to the severing of the intercellular bridge when cytokinesis is completed.
138 ed to the spindle midzone and the subsequent intercellular bridge, where it plays an essential role i
139 , a transient structure in the middle of the intercellular bridge, where they recruit CUL4 and MDM2 u
141 ds until the formation of a microtubule-rich intercellular bridge with the midbody at its centre.