ライフサイエンスコーパス: intercellular junction

1 actin polymerization complex at the podocyte intercellular junction.

2 -mediated feedback is a global effect on the intercellular junction.

3 tern of receptor proteins (a synapse) in the intercellular junction.

4 integration of ER tubules with an epithelial intercellular junction.

5 is a major component of the endothelial cell intercellular junction.

6 with IL-4, suggesting that IL-4 modifies the intercellular junction.

7 in and actin filaments are enriched near the intercellular junction.

8 lationally modify pre-existing components of intercellular junctions.

9 transition, leading to transient opening of intercellular junctions.

10 otes localized accumulation of E-cadherin at intercellular junctions.

11 adhesive plasma membrane structures known as intercellular junctions.

12 mple, CD46 and Her2/neu, that are trapped in intercellular junctions.

13 lear how ATP reaches the plasma membrane and intercellular junctions.

14 s an important early step in the assembly of intercellular junctions.

15 ted remodeling of the actin cytoskeleton and intercellular junctions.

16 mediated redistribution of occludin from the intercellular junctions.

17 ity complexes participate in the assembly of intercellular junctions.

18 diate adhesion and signaling at a variety of intercellular junctions.

19 with host membrane protrusions located near intercellular junctions.

20 ) are a family of adhesion proteins found in intercellular junctions.

21 hat Src and Cas associate with each other at intercellular junctions.

22 protein-tagged UNC-9 was localized to muscle intercellular junctions.

23 d vesicles and the consequent disassembly of intercellular junctions.

24 ll contacts and facilitated the formation of intercellular junctions.

25 pitates with ZO-1 and partially localizes to intercellular junctions.

26 sed throughout the nephron, predominantly at intercellular junctions.

27 al inoculation was overcome by disruption of intercellular junctions.

28 olocalized with cadherins and connexin 43 in intercellular junctions.

29 having inclusion bodies now, retained normal intercellular junctions.

30 from the intracellular compartment into the intercellular junctions.

31 ctivation, thus changing the organization of intercellular junctions.

32 ar overlap, catalyzing new sites for nascent intercellular junctions.

33 expression of p0071 could displace p120 from intercellular junctions.

34 to the membrane ruffles and the loosening of intercellular junctions.

35 unction proteins occludin and claudin-2 from intercellular junctions.

36 ested by membrane ruffling and disruption of intercellular junctions.

37 last- (NRK-49F) or epithelial-like (NRK-52E) intercellular junctions.

38 ranuclear speckles, and unexpectedly also in intercellular junctions.

39 ons and recruited by the cadherin complex to intercellular junctions.

40 elial cell monolayers, prior to formation of intercellular junctions.

41 sphorylated Cx43 signal occurred at sites of intercellular junctions.

42 d localization of cadherin and connexin43 at intercellular junctions.

43 nd with a putative role in the disruption of intercellular junctions.

44 an emphasis on regulation of the specialized intercellular junctions.

45 diate adhesion and signaling at a variety of intercellular junctions.

46 luminal surfaces; alpha(v) and VLA-1 were on intercellular junctions.

47 ssary to stabilize the receptors at sites of intercellular junctions.

48 43 phosphorylation and the loss of Cx43 from intercellular junctions.

49 ns/hour, indicating no appreciable damage to intercellular junctions.

50 cell proliferation, signaling pathways, and intercellular junctions.

51 ed the coupling coefficient (KC), across the intercellular junctions.

52 uding a lacunar system and multiple types of intercellular junctions.

53 a-catenin epitope a-18, as well as disrupted intercellular junctions.

54 tal networks in epithelial sheets to support intercellular junctions.

55 the primary tumor, which requires changes to intercellular junctions.

56 um relies on a threshold level of tension at intercellular junctions.

57 etween stalk and terminal cell with multiple intercellular junctions.

58 cells, using voltage-gated ion channels and intercellular junctions.

59 oskeleton and proper positioning/assembly of intercellular junctions.

60 r barrier and the re-establishment of apical intercellular junctions.

61 ractions on the organization and function of intercellular junctions.

62 -1 forms during assembly of endothelial cell intercellular junctions.

63 ls and as clusters of cells held together by intercellular junctions.

64 e, exceptionally reinforced, E-cadherin-rich intercellular junctions.

65 ation and proper organization of VE-cadherin intercellular junctions.

66 in cadherin-specific mechanotransduction at intercellular junctions.

67 RNA miR-199a-5p as an important regulator of intercellular junctions.

68 TC-dextran leakage, indicating disruption of intercellular junctions.

69 At P30, staining was localized to intercellular junctions.

70 in length before failing through rupture of intercellular junctions.

71 ocyanate-dextran flux; P < .05) and impaired intercellular junctions.

72 how ECM affects the spatial organization of intercellular junctions.

73 rentially spread from cell-to-cell at unique intercellular junctions.

74 ocated the chief sites of insulin release to intercellular junctions.

75 ))-beta(1) co-precipitation and strengthened intercellular junctions.

76 function is the integrity of the monolayer's intercellular junctions.

77 ture can regulate stability and tightness of intercellular junctions.

78 "leaky" tight junction protein claudin-2 at intercellular junctions.

79 ntemporaneous with the development of stable intercellular junctions [1].

80 absence of cytoskeletal cross-linking, major intercellular junctions (adherens junctions and DSMs) ar

81 e endoplasmic reticulum (ER) stress-mediated intercellular junction alterations accompanied by visual

82 ymphatic endothelial cell quiescence through intercellular junction and cytoskeleton stabilization an

83 and Connexin 30 from epidermal keratinocyte intercellular junctions and accumulation in cytoplasm.

84 ed at high concentration at endothelial cell intercellular junctions and at moderate density on the s

85 ial monolayers also developed focal adherens intercellular junctions and became more permeable when c

86 ical role because it controls cadherin-based intercellular junctions and cell polarity in many specie

87 ers by controlling assembly and functions of intercellular junctions and cell-matrix adhesions.

88 present at dermal microvascular endothelial intercellular junctions and colocalizes with VE-cadherin

89 thereby increasing pore size of endothelial intercellular junctions and enhancing movement across th

90 or "edge" cells, as the hepatocytes acquire intercellular junctions and form islands with time in cu

91 rgans, where cadherins may be engaged within intercellular junctions and hence inaccessible for antib

92 ionships between assembly and maintenance of intercellular junctions and highlight unappreciated role

93 e encodes a CDM family member that regulates intercellular junctions and is disrupted during tumorige

94 otifs responsible for ZO-1's localization to intercellular junctions and its newly demonstrated local

95 c protein alpha-catenin from E-cadherin-rich intercellular junctions and loss of adhesion.

96 s in regulating the formation of endocardial intercellular junctions and maintaining endocardial iden

97 odeling, interconversion of autocellular and intercellular junctions and migration over a luminal ext

98 PKPs localize to the cytoplasmic plaque of intercellular junctions and participate in linking the i

99 porting cell processes with normal-appearing intercellular junctions and portions of extruded hair ce

100 eraction of the GAS capsule with CD44 opened intercellular junctions and promoted tissue penetration

101 et formation, a polarized network of nascent intercellular junctions and radial actin cables assemble

102 VCAM-1 increased cortical actin filaments at intercellular junctions and reduced stress fibers across

103 VE)-cadherin, a key regulator of endothelial intercellular junctions and survival.

104 s play an important role in the formation of intercellular junctions and the control of intermembrane

105 n, branching, anastomosis, and maturation of intercellular junctions and the surrounding basement mem

106 ve mutant, disrupted the formation of apical intercellular junctions and their reassembly, impaired t

107 -1 was important for Scribble recruitment to intercellular junctions and TJ reassembly.

108 reduction in the capacity to maintain tight intercellular junctions and to actively reabsorb sodium.

109 agA appears to target H. pylori to host cell intercellular junctions and to disrupt junction-mediated

110 other tube; the two cells adhere and form an intercellular junction, and they become doughnut-shaped

111 s of neighboring cells maintain integrity of intercellular junctions, and alterations in the beta(1)

112 arrier, including keratinocyte cytoskeleton, intercellular junctions, and cell adhesion.

113 bin-induced hyperpermeability, disruption of intercellular junctions, and formation of stress fibers

114 revealed colocalization of Rap1 with JAM1 at intercellular junctions, and knockdown of JAM1 resulted

115 epithelial cells with prominent microvilli, intercellular junctions, and normal chromosomal characte

116 cortex-specifically the actin cytoskeleton, intercellular junctions, and protein complexes that dete

117 its stability and promotes its clustering at intercellular junctions, and that Prickle negatively reg

118 Disorganized intercellular junctions are critical for maintaining the

119 Intercellular junctions are crucial for mechanotransduct

120 ertoli cell membrane upon its secretion when intercellular junctions are formed.

121 Epithelial intercellular junctions are important components of the

122 s the presence of specialized low-resistance intercellular junctions as found in other embryos and nu

123 ation, can trigger DSG-2-mediated opening of intercellular junctions as shown by studies with recombi

124 Cadherin-mediated intercellular junctions as well as focal adhesions were

125 ent through a profound redistribution of the intercellular junctions, as well as recruitment and asse

126 determine the effects of EGFR inhibition on intercellular junction assembly and adhesion in oral squ

127 entral facet of organogenesis that relies on intercellular junction assembly to create functionally d

128 e Triton X-100 insoluble cytoskeleton during intercellular junction assembly, prior treatment with 10

129 n a Madin-Darby canine kidney cell model for intercellular junction assembly, TG treatment inhibited

130 and E-cadherin failed to redistribute to the intercellular junctions; assembly of the apical F-actin

131 anization at the SC cell cortex and promotes intercellular junctions at the level of the inner wall o

132 ing the molecular components of the podocyte intercellular junction, because several of these compone

133 defect-driven extrusion mechanism depends on intercellular junctions, because the weakening of cell-c

134 receptors have been shown to cluster at the intercellular junction between a B cell and an antigen-p

135 and branches, replacing the original single intercellular junction between stalk and terminal cell w

136 rn to a more "normal" localization at mainly intercellular junctions between intestinal epithelial ce

137 lular N-cadherin was accumulated in bands at intercellular junctions between SCs and was clustered at

138 tn/plakophilin family proteins interact with intercellular junction binding partners to differentiall

139 on required for blastocoel formation include intercellular junction biogenesis and a directed ion tra

140 c calcium alone is not sufficient for normal intercellular junction biogenesis if intracellular store

141 which increased the component attributed to intercellular junctions but not sarcoplasmic resistivity

142 show that EGFR inhibition stabilizes Dsg2 at intercellular junctions by interfering with its accumula

143 s whose role could be essential to stabilize intercellular junctions by shifting cadherin clusters fr

144 and inhibited the disruption of endothelial intercellular junctions by the IL-2RVE-cadcyto mutant.

145 Adherens junctions (AJs) are the major intercellular junctions by which cells sense and exert m

146 rates also have a new type of cadherin-based intercellular junction called the desmosome, which allow

147 receptors and ligands form a pattern in the intercellular junction called the immunological synapse,

148 d desmocollins, make up the adhesive core of intercellular junctions called desmosomes.

149 ll scattering encompasses the dissolution of intercellular junctions, cell-cell dissociation, cell sp

150 otypic and heterotypic signaling critical to intercellular junctions, cell-matrix interactions, and c

151 nbeta is essential for the redistribution of intercellular junction components from the lateral punct

152 crest cells and its ability to down-regulate intercellular junctions components.

153 do not form desmosomes, they possess unusual intercellular junctions composed of DP, PG and VE-cadher

154 Accordingly, disruption of intercellular junctions decreased the amount of co-preci

155 F-actin turnover in connecting actomyosin to intercellular junctions, defining a dynamic process requ

156 Intercellular junctions (desmoglein-1/3, desmoplakin, E-

157 sive interactions between PMN and epithelial intercellular junctions (desmosomes) that regulate PMN t

158 ion has been given to the possibility of new intercellular junctions developing between cardiocytes w

159 nd patterns (several microns in size) in the intercellular junction during immunological synapse form

160 modeling their cytoskeletal architecture and intercellular junctions during a process known as efface

161 rcalated disk implies a possible role at the intercellular junctions during cardiac ischemia.

162 reorganization of occludin and ZO-1 into the intercellular junctions during the calcium-induced reass

163 ight into p120-catenin's role as guardian of intercellular junction dynamics.

164 In the absence of mXinbeta, the intercellular junctions failed to be restricted to the t

165 MMP20 and MTSS1 (promotes actin assembly at intercellular junctions) for left ventricular systolic f

166 However, the onset of defects in intercellular junction formation precedes the onset of e

167 Endothelial cell intercellular junction formation was characterized by im

168 pects of cell biology, including morphology, intercellular junction formation, and asymmetric protein

169 data support the model that during podocyte intercellular junction formation, engagement of the neph

170 se and tensin homolog (PTEN), which impaired intercellular junction formation, prolactin receptor tra

171 egulation of rho-signalling, cytokinesis and intercellular junction formation, we investigated the ef

172 eficient endocardium, indicating a defect in intercellular junction formation.

173 Our data suggest that intercellular junctions formed by neurexins, such as jun

174 ly up-regulated during the redistribution of intercellular junction from the lateral membrane of card

175 influenced the expression of genes encoding intercellular junction (IJ) proteins, whereas the loss o

176 apparatus that can apply mechanical force to intercellular junction in a confluent monolayer of cells

177 e describe the discovery of actin-associated intercellular junctions in Dictyostelium.

178 to DSG2, triggered the transient opening of intercellular junctions in epithelial cells.

179 l dynamics of N-cadherin interactions across intercellular junctions in living cells using a genetica

180 These findings demonstrate the plasticity of intercellular junctions in lymphatics during development

181 es identify PMP22 as an early constituent of intercellular junctions in the developing and mature rat

182 to recent electron microscopical studies of intercellular junctions in the early chick embryo.

183 number of the caveolae and severely loosened intercellular junctions in the vacuolated region.

184 Synapses are specialized intercellular junctions in which cell adhesion molecules

185 is a transmembrane component of specialized intercellular junctions, including the myocardial interc

186 gulate cell functions directly influenced by intercellular junctions, including the strength of cell

187 g and regulating assembly and disassembly of intercellular junctions is a subject of intensive resear

188 Because dissolution of intercellular junctions is frequently an initial step in

189 t with the host cell membranes that comprise intercellular junctions is not known.

190 Intermediate filament (IF) attachment to intercellular junctions is required for skin and heart i

191 ollins (Dscs), comprise the adhesive core of intercellular junctions known as desmosomes.

192 Alpha(v) and VLA-1 on intercellular junctions may participate in re-establishi

193 tion was not required, indicating that other intercellular junctions mediated this growth regulatory

194 Axl depletion altered expression of intercellular junction molecules increasing cell-cell ad

195 as a cell adhesion molecule at the podocyte intercellular junction necessary for maintaining glomeru

196 uring prostate and mammary involution is the intercellular junction of adjacent secretory epithelium.

197 The tight junction is the most apical intercellular junction of epithelial cells and regulates

198 in homophilic intermolecular interaction at intercellular junctions of apoptotic cells and macrophag

199 ic reporter mice, we describe VE-cadherin at intercellular junctions of arachnoid and pia mater cells

200 on of JAM-A was observed in human RPE and in intercellular junctions of ARPE-19 monolayers.

201 Here T2-TrpRS was shown to bind at intercellular junctions of endothelial cells (ECs).

202 These studies support a role for PMP22 at intercellular junctions of epithelia and may indicate a

203 ing of lymphocyte transmigration through the intercellular junctions of high endothelial venules is l

204 tial cell-cell adhesions and that the stable intercellular junctions of nontransformed epithelial cel

205 Therefore, we studied intercellular junctions of primary human MFs derived fro

206 The intercellular junctions of the endothelial cells of SC w

207 nn cells is unknown, the protein is found at intercellular junctions of various epithelia and endothe

208 v) no orosomucoid molecules are found in the intercellular junctions or at the abluminal exits of int

209 Spirochetes were not observed within intercellular junctions or membrane-bound compartments i

210 properly established and maintained podocyte intercellular junction, or slit diaphragm, is a necessar

211 omerular basement membrane, and the podocyte intercellular junction, or slit diaphragm.

212 Synapses are highly specialized intercellular junctions organized by adhesive and scaffo

213 ed as a key modulator of cadherin-containing intercellular junctions, particularly in tumors that ove

214 uent double-cell calculations then yield the intercellular junction permeability, which is translated

215 by transducing from the specialized podocyte intercellular junction phosphorylation-mediated signals

216 that ECM affects the degree of stability of intercellular junction positioning and the magnitude of

217 CM in the mechanical regulation of cells and intercellular junction positioning.

218 demonstrate that cell intercalations remodel intercellular junctions predominantly between the mediol

219 Desmosomes are adhesive intercellular junctions prominent in the skin and heart.

220 and diseased tissue samples were studied for intercellular junction protein distribution with confoca

221 se data suggest that stiff substrates change intercellular junction protein localization and degradat

222 cell line MIN6, each of which expressed key intercellular junction proteins (connexin-36, E-cadherin

223 tigated the effects of IL-4 on expression of intercellular junction proteins and whether such effects

224 d a C-terminal region that is similar to the intercellular junction proteins dlg-A, PSD95/SAP90, SAP9

225 barrier function and mislocalization of key intercellular junction proteins in the tight junction an

226 pidermal differentiation, and derangement of intercellular junction proteins.

227 ct from those regulating expression of other intercellular junction proteins.

228 Essential roles for FLNA in intercellular junctions provide a mechanism for the dive

229 Because podocyte intercellular junction receptor Nephrin plays a role in

230 ent progress in understanding the role of an intercellular junction referred to as the apical junctio

231 on is primarily regulated by the apical most intercellular junction referred to as the tight junction

232 Intestinal epithelial intercellular junctions regulate barrier properties, and

233 dothelial focal adhesion kinase (FAK), a BBB intercellular junction regulator, facilitated parasite t

234 It requires intercellular junction remodeling, a process typically p

235 that S1P induced the translocation of Rac to intercellular junctions, resulting in junctional sealing

236 cting components of the specialized podocyte intercellular junction, results in abnormal podocyte mor

237 reased MT density and altered MT dynamics at intercellular junction sites.

238 tor complexes and their assembly into larger intercellular junction structures and discuss emerging p

239 ondria-rich varicosities and the presence of intercellular junctions suggest that the varicosities ma

240 ellular enclosed lumens with autocellular or intercellular junctions, suggesting that heterogeneous m

241 protein kinases and in proteins specific for intercellular junctions, suggesting that it may be a sig

242 tial pattern of receptors and ligands in the intercellular junction (synapse) is different during thy

243 In addition, withdrawal of cadherins from intercellular junctions temporally precedes the removal

244 y arrest and form radially symmetric, stable intercellular junctions termed immunological synapses wh

245 HIV to their target CD4(+) cells through an intercellular junction, termed the virologic synapse.

246 at the calyceal membrane resembles a type of intercellular junction that is rare in vertebrates, the

247 The chemical synapse is a specialized intercellular junction that operates nearly autonomously

248 on factor that is regulated by components of intercellular junctions that are affected by cytokines a

249 ing components of the desmosome, specialized intercellular junctions that confer mechanical strength

250 Podocyte slit diaphragms (SDs) are intercellular junctions that function as size-selective

251 s represents a hyper-adhesive state of these intercellular junctions that is crucial for the maintena

252 Desmosomes are intercellular junctions that mediate cell-cell adhesion

253 Synapses are highly specialized intercellular junctions that mediate the transmission of

254 ell-cell adhesion structures - also known as intercellular junctions - that are essential for barrier

255 ential roles of the most prominent epidermal intercellular junction, the desmosome, in establishing e

256 nce is the strain level that may disrupt the intercellular junction, therefore altering lung impedanc

257 Desmosomes are critical elements of intercellular junctions; they are punctate structures ma

258 that might interact across the foot process intercellular junction through interactions between Neph

259 Collagen I also disrupted VE-cadherin from intercellular junctions through a Src-dependent mechanis

260 ing the structure and function of epithelial intercellular junctions through direct and indirect mech

261 progression of CCM lesions by destabilizing intercellular junctions through increased cell contracti

262 Rac1 regulate formation of stress fibers and intercellular junctions, thus modulating endothelial mon

263 in intestinal epithelial cells are gated by intercellular junctions (tight junctions and adherens ju

264 nisms that coordinate their trafficking into intercellular junctions to regulate their proper ratio a

265 and switched expression of beta-catenin from intercellular junctions to the nucleus and cytoplasm, in

266 ved from their off-centered position next to intercellular junctions toward extracellular matrix adhe

267 identified immunohistochemically at apparent intercellular junctions was phosphorylated.

268 Similarly, loss of desmosomes (intercellular junctions) was seen in placental tissues f

269 ted to a defect in the number or assembly of intercellular junctions, we cultured Hailey-Hailey disea

270 thin the left ventricle appeared normal, but intercellular junctions were ill-formed or absent, consi

271 tosols of the testis and epididymis when the intercellular junctions were not previously disrupted, s

272 Intercellular junctions were permanently displaced, and

273 redistribution of occludin and ZO-1 from the intercellular junctions were prevented by PP2.

274 or concentrating PECAM-1 at endothelial cell intercellular junctions, where it functions to facilitat

275 cadherin Flamingo localizes on both sides of intercellular junctions, where it interacts homophilical

276 Ab) used to treat solid tumors is limited by intercellular junctions which tightly link epithelial tu

277 nges are driven by pulsatile contractions of intercellular junctions, which are rectified to produce

278 In coculture, PMFs developed intercellular junctions with ECs and enhanced the format

279 d diminished VE-cadherin and beta-catenin at intercellular junctions, with resultant intercellular ga

280 omain proteins usually localized at sites of intercellular junctions, yet little is known about their