ライフサイエンスコーパス: interconvert

1 uctures, such as G-quadruplexes, to form and interconvert.

2 These two forms do not reversibly interconvert.

3 ormations that can take seconds or longer to interconvert.

4 nd amorphous phases coexist and continuously interconvert.

5 two cage isomers can coexist in solution and interconvert.

6 and antitoxins from disparate systems can be interconverted.

7 lls derived from separate germ layers can be interconverted.

8 structures can be (transiently) accessed and interconverted.

9 Attempts to interconvert 1 and 3 with base were unsuccessful, but en

10 A; and 2-hydroxyisobutyryl-CoA mutase, which interconverts 2-hydroxyisobutyryl-CoA and (3S)-hydroxybu

11 -butyryl-CoA; ethylmalonyl-CoA mutase, which interconverts (2R)-ethylmalonyl-CoA and (2S)-methylsucci

12 MCM interconverts (2R)-methylmalonyl-CoA and succinyl-CoA.

13 ophosphate (IPP) kinase/pyrophosphatase that interconverts 5-IP7 and 1,5-IP8.

14 droxysteroid dehydrogenase (11beta-HSD) that interconvert active cortisol and inactive cortisone.

15 s, show that the resting catalyst adopts two interconverting active-site conformations, only one of w

16 n environments with competing reactions that interconvert adenine nucleotides such as in permeabilize

17 within the mature mTEC subset and, in vitro, interconverted along this sequence.

18 lkaline phosphatase superfamily members that interconvert alpha-D-ribose 5-phosphate (ribose 5-phosph

19 During the trajectories, the spin labels interconvert among a fairly large number of conformation

20 the DNA-binding domains of MutS dynamically interconvert among multiple conformations when the prote

21 ynamical study shows that (1) G and L do not interconvert and (2) the evolving system can switch from

22 -ring allosteric communication by which they interconvert and the coupling between allosteric transit

23 LA populates an ensemble of slowly (>100 ms) interconverting and conformationally heterogeneous unfol

24 Cys-DNIC and Cys-RSE interconvert, and the rates of this process depend on th

25 Sulfonium salts 3 and 4 do not appear to interconvert, and the system as a whole had fewer pathwa

26 te coefficients by which these intermediates interconvert; and thereby to elucidate a chemical kineti

27 All sites are observed to interconvert at 120 K such that the distribution of the

28 exists as two (or more) distinct states that interconvert at a rate much faster than the rate of diss

29 ith an additional ortho-methyl group did not interconvert at ambient temperatures and were readily re

30 ts that the covalent and distonic dimers may interconvert at high energies.

31 Complexes 7b and 7c do not interconvert at room temperature in CD(2)Cl(2) and form

32 the lithiated methylphosphine sulfide could interconvert at temperatures above 0 degrees C.

33 ologically active molecules exist as rapidly interconverting atropisomeric mixtures.

34 he gate and allows the selectivity filter to interconvert back to its conductive conformation (recove

35 Migration modes can interconvert based on changes in cell adhesion, cytoskel

36 that purified 30S ribosome subunits readily interconvert between "active" and "inactive" conformatio

37 first exposure to cold temperatures and then interconvert between "dormant beige" and "active beige"

38 lytic domain of protein tyrosine kinases can interconvert between active and inactive conformations i

39 pening of the beta-lactam, the pyrroline may interconvert between an enamine (2-pyrroline) form and t

40 imilarity to yeast prion proteins, which can interconvert between an intrinsically disordered and an

41 e stem cell pool, in which cells continually interconvert between As and syncytial states.

42 iological monomers, which can hydrolytically interconvert between cyclic and acyclic forms, alone or

43 These complexes can interconvert between different I L V N+L He M variants v

44 y and of a spin-state change and can rapidly interconvert between different spin states with differen

45 rdinates for translocation were then used to interconvert between experimental rates and measures of

46 e a degree of phenotypic plasticity as cells interconvert between individual and collective migration

47 hich Fis1 activity depends on its ability to interconvert between monomer and dimer species.

48 Recent studies show that GPCRs rapidly interconvert between multiple states although our abilit

49 Phytochromes interconvert between red-absorbing P(r) and far-red-abso

50 e protein complexes are dynamic in that they interconvert between several alternate configurations.

51 uivalent AaeFd4 and CpFd variants reversibly interconvert between similar valence-localized S = 1/2 a

52 s possessing semicarbazide residues that can interconvert between sp(2) and sp(3) hybridization, resu

53 sion length of over 40 nm and whose excitons interconvert between the singlet and triplet states ~36

54 bpopulations are stable in that cells do not interconvert between the two expression patterns.

55 We show that the LBDs interconvert between three conformations: resting, activ

56 randomly generated RNA sequence are found to interconvert between three or more states, including str

57 ly a combination of mutations is required to interconvert between TrtA, BiuH functions.

58 ted by a metallic surface and can reversibly interconvert between two electronic states.

59 of the ligands, the resulting complex can be interconverted between a flexible, semiopen state and a

60 nce suggests that liver cells are capable of interconverting between cellular states of distinct phen

61 earing molecules that dynamically isomerize, interconverting between enantiomers without cleavage of

62 ransport ions across biological membranes by interconverting between high (E1) and low (E2) ion-affin

63 n which preliminary twisting represents Rad4 interconverting between search and interrogation modes.

64 rent nature of proteins as dynamic molecules interconverting between structures with varying energies

65 first time, that the lid in apo-MDM2 slowly interconverts between a "closed" state that is associate

66 The sensor itself stably interconverts between all-trans-15-anti and 13-cis-15-sy

67 formamidopyrimidine (AFB-FAPY) adduct, which interconverts between alpha and beta anomers.

68 scribe in atomic-level detail how Abl kinase interconverts between an active and two discrete inactiv

69 TP:phosphocholine cytidylyltransferase (CCT) interconverts between an inactive soluble and active mem

70 mplitude motions and the carbohydrate moiety interconverts between Fc-bound and unbound forms, enabli

71 opy, we demonstrate that in solution, the CP interconverts between multiple conformations whose relat

72 e we present a pulse sequence technique that interconverts between singlet spin order and bulk magnet

73 The photoreceptor phytochrome B (phyB) interconverts between the biologically active Pfr (lambd

74 been identified in the salvage pathway that interconverts between the six vitamin B6 vitamers.

75 of PLN, whose cytoplasmic regulatory domain interconverts between three different states: a ground T

76 ring turnover, its catalytic subunit (PKA-C) interconverts between three major conformational states

77 ation suggests that the T.th. RuvC homodimer interconverts between two asymmetric conformations, with

78 RuvC homodimer interconverts between two asymmetric conformations, with

79 for hepcidin that, at ambient temperatures, interconverts between two different conformations, which

80 The two acyl-enzyme complex structures can interconvert by movement of the Thr-111 side-chain alcoh

81 g molecules, as they are rapidly produced or interconverted by a set of dedicated enzymes.

82 ched N-acylamide side chain, GalNAzMe is not interconverted by epimerization to the corresponding N-a

83 quilibrium between different states, readily interconverted by ligand binding.

84 seven species of phosphoinositides that are interconverted by lipid kinases and phosphatases.

85 The different oligomers can be interconverted by the addition or subtraction of tetrame

86 phate) are highly energetic cellular signals interconverted by the diphosphoinositol pentakisphosphat

87 and homothallic Dothideomycete fungi can be interconverted by the exchange of MAT genes.

88 te are rapidly, selectively, and efficiently interconverted by tungsten-containing formate dehydrogen

89 ve thermostable polymerases that efficiently interconvert C2'-OMe-modified oligonucleotides and their

90 l complex were prepared and determined to be interconverting catalyst resting states.

91 ogens, indicating fast proton shuttling that interconverts cationic and neutral histidines.

92 the absence of external gradients by forming interconverting cell states.

93 s of both subtypes present and suggestive of interconverting cell states.

94 o by storing and releasing H(2) on demand by interconverting CO(2)/H(2) and formate with minimal bias

95 nhydrases (CAs) are zinc metalloenzymes that interconvert CO2 and HCO3 (-) In plants, both alpha- and

96 djacent PPXY pairs to produce an ensemble of interconverting complexes of variable stoichiometries, b

97 its strongest binder(s) from the library of interconverting compounds.

98 ur cluster assembly, apo-IscU, populates two interconverting conformational states, one disordered (D

99 vious studies showed that IscU populates two interconverting conformational states: one structured (S

100 a coli has been shown to populate two slowly interconverting conformational states: one structured (S

101 ensional energy landscape where ensembles of interconverting conformational substates channel the enz

102 r, direct experimental links between rapidly interconverting conformations and the chemical steps of

103 These many interconverting conformations classify single cyanostars

104 ghly flexible N terminus and multiple slowly interconverting conformations in different parts of the

105 Determining the interconverting conformations of dynamic proteins in ato

106 These loops may contain interconverting conformations that are more globally col

107 Instead, they populate ensembles of rapidly interconverting conformations with marginal structural s

108 we show that SRP binds RNCs in multiple and interconverting conformations, and that conversely, RNCs

109 s in an intrinsically disordered ensemble of interconverting conformations, which has made its therap

110 Similar ensembles of interconverting conformers may be common in multivalent

111 MGs are ensembles of interconverting conformers that contain (non-)native sec

112 red proteins (IDPs) are dynamic ensembles of interconverting conformers that often contain many proli

113 y observed for proteins do not correspond to interconverting conformers, but rather to high numbers o

114 ule is considered in terms of an ensemble of interconverting conformers, each with potentially divers

115 tners and thus exist as dynamic ensembles of interconverting conformers, often highly soluble in wate

116 d are best described by ensembles of rapidly interconverting conformers.

117 natorial chemistry where the library members interconvert continuously by exchanging building blocks

118 evidence, we propose that CopG has a role in interconverting Cu(I) and Cu(II) to minimize toxic effec

119 The PiB-florbetapir association was used to interconvert cutoffs for Abeta positivity and negativity

120 The enzyme interconverts d- and l-lactic acid, which is important f

121 ally distinct CSC populations, which seem to interconvert depending on the host tissue microenvironme

122 hydroneopterin triphosphate epimerase, which interconverts dihydroneopterin triphosphate and dihydrom

123 lium isomers were identified, which could be interconverted directly into one another with light.

124 IL-10(+)CD8 and IL-10(-)CD8 T cells interconvert during acute disease, possibly based on rec

125 when they exist in complex mixtures, such as interconverting dynamic combinatorial libraries.

126 ons point to a prime requirement for AChE to interconvert dynamically between sequential conformation

127 al or exists as a racemic mixture of rapidly interconverting enantiomeric conformations or configurat

128 cally consist of racemic mixtures of rapidly interconverting enantiomeric conformers able to recogniz

129 eactions are proposed to proceed via rapidly interconverting encounter pairs with an exciplex as inte

130 of cis-enolate 27 from a mixture of rapidly interconverting enolates.

131 bon units to formate requires several folate-interconverting enzymes in mitochondria.

132 of tetrahydrofolate (THF) and several folate-interconverting enzymes in the mitochondrial matrix.

133 The UDP-sugar interconverting enzymes involved in UDP-GlcA metabolism

134 h was found to exist as a mixture of rapidly interconverting epimers.

135 h open and closed conformations of the cleft interconverting, even in the rigor actomyosin complex.

136 ure of two cyclochiral conformers, which are interconverting fast on the (1)H NMR time scale, accordi

137 uctose-2,6-bisphosphatases (PFKFB1-4), which interconvert fructose 6-phosphate and Fru-2,6-BP.

138 omain a second photosensory module, a Pr/Pfr-interconverting GAF-GAF bidomain (SynCph2(1-2)).

139 train O157 contained an epimerase capable of interconverting GlcNAc-P-P-Und and GalNAc-P-P-Und.

140 Both recombinant enzymes were able to interconvert glucose-phosphates, as well as acting on th

141 se isomerase (PGI) and phosphoglucose mutase interconverting glucose 6-phosphate, fructose 6-phosphat

142 e 1 (PGM1) encodes the metabolic enzyme that interconverts glucose-6-P and glucose-1-P.

143 ng various approaches that have been used to interconvert GPCR agonists, partial agonists, and antago

144 [FeFe] hydrogenases interconvert H(2) into protons and electrons reversibly

145 Hydrogenases interconvert H2 and protons at high rates and with high

146 e enzymes use first-row transition metals to interconvert H2 with protons and electrons, reactions th

147 Thermoelectrics interconvert heat to electricity and are of great intere

148 A dynamic covalent library of interconverting imine constituents, dissolved in an acet

149 spectroscopy further shows these structures interconvert in 30 ps.

150 ) gp150-specific CD4(+) T cells were able to interconvert in a bidirectional manner upon secondary Ag

151 imers, and/or oligomers and if these species interconvert in a ligand-dependent manner are among the

152 and with lifetimes on the order of 1 s that interconvert in an apparent two-state reaction.

153 We demonstrate that these two variants can interconvert in crystallo in response to pH perturbation

154 ows that the ion has two distinct forms that interconvert in milliseconds to seconds depending on the

155 t the aS and aR isomers of compound 1 do not interconvert in solution, we investigated how biological

156 dies show that the open and closed forms can interconvert in solution, with low salt favoring the clo

157 be two conformations of NAC that can freely interconvert in the absence of a coeffector.

158 e two substrate conformations cannot readily interconvert in the active site.

159 Notably, qNSCs and aNSCs can interconvert in vitro.

160 in vivo, these precursor populations readily interconvert in vitro.

161 active and inactive states that are readily interconverted in response to several sets of stimuli an

162 pools were functional in that they could be interconverted in two ways: (i) by exposure to 10S- vers

163 ers identify an N-terminal domain in SM that interconverts in a cholesterol-sensitive manner between

164 here cross-linked native protein dimer, N-N, interconverts in a two-state transition with a dimer whe

165 This duplication allows the protein to interconvert, in a ligand-dependent fashion, between two

166 The ability to interconvert information between electronic and ionic mo

167 We found that the two interconverting interaction geometries were conserved in

168 is Araf, UDP-Arap must exit the Golgi to be interconverted into UDP-Araf by UDP-Ara mutases that are

169 However, how folded states interconvert is largely unknown due to the inability to

170 Whether, and if so how, they interconvert is unclear.

171 How the states are interconverted is not understood, and whether the histon

172 s include isobutyryl-CoA mutase (ICM), which interconverts isobutyryl-CoA and n-butyryl-CoA; ethylmal

173 rotation and developing a mixture of rapidly interconverting isomers.

174 horylation and competition of substrates for interconverting kinase (Cdk) and phosphatase.

175 Moreover, we found that Alr2 could interconvert l- and d-serine and that Alr2 bound to l- a

176 While an unequal population of rapidly interconverting left- and right-handed conformers of a h

177 is sufficient to refold a helical oligomer, interconverting M and P screw-sense preference.

178 This inherent plasticity between the interconverting macrostates is compatible with a conform

179 However, mutants lacking enzymes that interconvert methylene H4F and formate are unable to gro

180 These natural products were isolated as an interconverting mixture of four structural- and stereois

181 bilayer, these proteins exhibit a number of interconverting modes of collective ATP-driven dynamic p

182 its synthesis in 95% yield from a mixture of interconverting molecules of different ring sizes in a o

183 ass of lipids (sphingolipids) is a family of interconverting molecules that play key roles in numerou

184 retical analyses showed that MSA-2 exists as interconverting monomers and dimers in solution, but onl

185 s unfolded states (many unfolded basins that interconvert more rapidly with the native state than wit

186 er-residue amide hydrogen exchange rates for interconverting native and invisible states so long as t

187 non-cooperative transition leads to multiple interconverting native-like states, in which both zinc a

188 However, the highly dynamic and interconverting nature of amyloidogenic species limits b

189 of NO at bioinorganic metal centres that can interconvert NO and RSNO molecular signals at copper sit

190 FACT promotes these opposing goals by interconverting nucleosomes between the canonical form a

191 When structures that interconvert on a given time scale are lumped together,

192 at exists as two predominant conformers that interconvert on a slow timescale.

193 d E forms are distributed in a 1:4 ratio and interconvert on a time scale of 45 ms.

194 iable exist in multiple conformations, which interconvert on a timescale comparable with the rates of

195 ds into multiple distinct native states that interconvert on a timescale much longer than that of cat

196 dies have indicated these two forms of Y456T interconvert on the approximate time scale of tens of mi

197 hey are usually minimally frustrated and may interconvert on the micro- to millisecond time scale.

198 The two states interconvert on the millisecond time scale.

199 different hydrophobic contact surfaces that interconvert on the milliseconds timescale.

200 olving an ensemble of structures that do not interconvert on this time scale.

201 to an analytic result for a two-state system interconverting on a timescale slower than the interphot

202 echanism involving two conformational states interconverting on the second timescale.

203 heterogeneous ensemble of oligomeric species interconverts on timescales comparable to those of aggre

204 a(2+) is bound, a 3:2 mixture of dynamically interconverting open (active) and primed-closed (partial

205 The clusters coherently interconvert over an ~1-electron volt energy barrier wit

206 ipped (A) vs pseudoparallel (B)) that do not interconvert over time in a period of at least six month

207 he apicomplexan-specific DAG-kinase-1, which interconverts PA and DAG, and whose depletion impairs eg

208 s improved selectivity compared to a rapidly interconverting parent molecule.

209 ogether, these results point to distinct yet interconverting phenotypes within patient-derived circul

210 o a family of reversible decarboxylases that interconvert propenoic or aromatic acids with the corres

211 zyme pyruvate,orthophosphate dikinase (PPDK) interconverts pyruvate and phosphoenolpyruvate, and is f

212 pimerases (GRMZM2G061988, At5g49970) rapidly interconverted (R)- and (S)-NAD(P)HX, as did a truncated

213 The two enantiomers interconvert (racemize) through an achiral intermediate

214 Using an organometallic route, the clusters interconvert rapidly and self-assemble in solution based

215 h structures are significantly populated and interconvert rapidly.

216 ntly on the relative abundances of the three interconverting Re-containing species at steady state.

217 ton in water and the mechanism by which they interconvert remain elusive.

218 f Tregs and Tconvs that do not substantially interconvert respond during experimental allergic enceph

219 The results revealed three interconverting reverse transcriptase-DNA/RNA species; 4

220 constants (K(d)) for both rapidly and slowly interconverting riboswitch-ligand pairs as validated thr

221 2 e(-) /2 H(+) reactions are described that interconvert [Ru(II) (bpy)(en*)2 ](2+) and [Ru(IV) (bpy)

222 Pre-equilibration of an interconverting set of isomeric allylic azides is couple

223 tence of distinct protein conformations that interconvert slowly and exhibit different affinities for

224 -methyl group, the diastereomeric precursors interconvert slowly at ambient temperatures.

225 a indicate that the two diastereoisomers are interconverting slowly in solution on the (1)H NMR time

226 ts the catabolic and anabolic reactions that interconvert small molecules (metabolites) through the a

227 , in that all four diastereomeric states can interconvert solely photochemically.

228 exchange mass spectrometry to resolve slowly interconverting species, we found that beta-sheet beta12

229 l that allows simulating ATDs resulting from interconverting species.

230 HER2(+) and HER2(-) circulating tumour cells interconvert spontaneously, with cells of one phenotype

231 ate a structurally heterogeneous ensemble of interconverting states, play important roles in many bio

232 e C99 homodimer supports a variety of slowly interconverting structural states.

233 Janus, for predicting mutations required to interconvert structurally related but functionally disti

234 s a molten globular state consisting of many interconverting structures can fold into either a helix-

235 is design fosters efficient HIV-1 fusion via interconverting structures while, at the same time, affo

236 ed conformation to one with multiple dynamic interconverting structures.

237 ron-density sampling to structurally unravel interconverting substates of the human proline isomerase

238 monoanion exists as an equilibrating pair of interconverting tautomers and not as a single symmetric

239 t the ion exists as an equilibrating pair of interconverting tautomers and not as a single symmetric

240 d that KP1212 existed as a broad ensemble of interconverting tautomers, among which enolic forms domi

241 ral sensitivity to distinguish among rapidly interconverting tautomers.

242 The ability of KpHpxA to interconvert the (R)- and (S)-enantiomers of allantoin i

243 hey also have salvage pathways that serve to interconvert the different vitamers.

244 use of a polarized electrode to efficiently interconvert the ferric (Fe(3+)) and ferrous (Fe(2+)) fo

245 The approach to interconvert the secretory fate of proteins in vivo has

246 ee successive 120 degrees turns of the rotor interconvert the sites through these three states, hydro

247 ate for the first time the ability of AXS to interconvert the two reaction products.

248 a rational protein engineering approach, we interconverted the enzymatic specificity of alpha- GAL a

249 time, showed that six complete oscillations interconverting the capsule species present in solution

250 rized at atomic resolution by quantitatively interconverting the isomers in the crystal both thermall

251 er protein (ACP):phosphate transacylase that interconverts the two acyl donors in Gram-positive bacte

252 Mammalian sterile 20 kinase 4 (MST4) largely interconverted their phosphorylation site preferences.

253 Thermoelectric materials interconvert thermal gradients and electric fields for p

254 re or from triplex intermediates involved in interconverting these structures.

255 le due to autodepalmitoylation, creating two interconverting thioesterase pools: palmitoylated APT on

256 m (C) into those present in A or B partially interconverts this substrate selectivity.

257 These adducts can interconvert through a [3,3] sigmatropic shift (Cope rea

258 that nanosheets and tubes can spontaneously interconvert through manipulation of the assembly pH and

259 s of structurally related compounds that can interconvert through reversible chemical reaction(s).

260 We found that species rapidly interconvert through the action of ZDHHC16 and the Acyl

261 ted that distinct states of pluripotency can interconvert through the modulation of both cell-intrins

262 two major green and blue subfamilies can be interconverted through a L/Q point mutation at position

263 ing transcription, appear to be incapable of interconverting through unfolding and refolding, presuma

264 in dimethylsulfoxide (DMSO), the two isomers interconvert to each other.

265 HLA-A2 and -B8 expression profiles could be interconverted to a large extent by mutual exchange of G

266 ous results that GlcNAz can be metabolically interconverted to GalNAz, whereas GlcNAlk does not, ther

267 The 4Fe(H) interconverts to a [2Fe-2S] cluster in parts of the popu

268 s viscosity-dependent dynamics that serve to interconvert two excited singlet state conformations of

269 ned UDP-galactose 4'-epimerase (GALE), which interconverts two pairs of essential NSs.

270 2)F(12) structure was reported recently) are interconverted, two of them reversibly.

271 tide sugar mutases have been demonstrated to interconvert UDP-Larabinopyranose (UDP-Arap) and UDP-L-a

272 ene that encodes a UDP-arabinose mutase that interconverts UDP-arabinopyranose and UDP-arabinofuranos

273 of UDP-galactose 4'-epimerase (GALE), which interconverts UDP-galactose and UDP-glucose, as well as

274 te were shown to reversibly and controllably interconvert under appropriate conditions, with an accom

275 These bilayer-related architectures interconvert under suitable conditions.

276 e two enantiomers of the electrophile, which interconvert under the reaction conditions (dynamic kine

277 to cell surface receptors can be reversibly interconverted under physiological conditions.

278 fferent approaches are required for dynamic, interconverting, unfolding, and refolding proteins.

279 Reactions are described that interconvert vanadium(IV) oxo-hydroxo complexes [V(IV)O(

280 east eight monomeric quadruplex species that interconvert very slowly at room temperature.

281 anism is composed of eight enzyme forms that interconvert via 22 rate constants, each of which was de

282 These two species interconvert via a rapid and reversible intramolecular p

283 shown to exist as three diastereomers, which interconvert via a reversible cyclic reaction scheme.

284 h represent active "on" or "off" states that interconvert via transient intermediates.

285 in this distribution during transitions that interconvert weak and strong microtubule binding states.

286 equilibrium between two enzyme species that interconvert with a rate constant slower than turnover.

287 ta-sheet surface that allowed this domain to interconvert with a second, stable conformation.

288 These neutral species interconvert with cations in a complex series of proton

289 These conformations interconvert with rate constants that depend on the stag

290 At lower temperature, they interconvert with their stannylstannylene isomers with p

291 mpetent to bind immune-stimulating FcgammaRs interconverted with Fc conformations distinct from those

292 namic equilibrium of inactive states rapidly interconverting with a low population of active species.

293 lar reaction conditions, 1-phenylnaphthalene interconverts with 2-phenylnaphthalene, with the latter

294 rgy landscape during fast search but rapidly interconverts with a "hemispecific" binding mode in whic

295 poSOD1(2SH) have shown that the ground state interconverts with a series of sparsely populated and tr

296 1 degrees C, we found that the native state interconverts with a transiently formed, sparsely popula

297 y structured low populated intermediate that interconverts with the folded, ground state on the milli

298 osphates and PI 3-phosphates are dynamically interconverted within the endocytic pathway and how this

299 exes are dynamic and their architectures can interconvert without dissociation.

300 e pathways with multiple crystal phases that interconvert without free-energy barriers and could prov