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1 is method achieved a quantitative removal of interfering (137)Cs in the deposition product and proved
5 on is accurate for a wide range of different interfering background structures constructed from many
6 ty of Candida species and remove most of the interfering blood cells for accurate molecular analysis,
7 or was further investigated by studying with interfering compounds (sucrose, dopamine, starch, and bo
8 gradient elution mode in order to eliminate interfering compounds and improve separation and peak sh
13 n a cell density-dependent manner; thus, AHL-interfering enzymes constitute new promising antimicrobi
14 gulation of VASP ubiquitination by a pair of interfering ligases is a critical element of VASP dynami
15 typically suffers from strong sensitivity to interfering matrices and inability to detect the complet
18 o a complex food as green coffee because the interfering native fluorescent products made the quantif
19 individual beads, which prevents the optical interfering of background noise as well as allowing one
22 dels to describe co-infection with defective interfering particles, which are an emerging alternative
23 rtantly, administration of Pdcd4 siRNA or an interfering peptide that interrupts the Pdcd4-eIF4A comp
24 plasm formation, delayed replication, and an interfering phenotype during coinfection with wild-type
27 idually by pharmacological inhibition, small interfering ribonucleic acid (siRNA) depletion, and anti
29 are controlled by the Piwi-interacting small interfering RNA (piRNA) pathway in gonads, while the sma
30 at transposable element (MITE)-derived small interfering RNA (siRNA) (here referred to as siR109944)
31 either by chemical inhibitor GW4869 or small interfering RNA (siRNA) against SMPD3 results in defects
32 tion Altriol Nucleic Acid (ANA) within small interfering RNA (siRNA) duplexes that were otherwise ful
35 or, the defining subunit of mTORC1, by small interfering RNA (siRNA) negatively affects ZIKV protein
36 A (piRNA) pathway in gonads, while the small interfering RNA (siRNA) pathway is dedicated to TE somat
37 this study, we performed a large-scale small interfering RNA (siRNA) screen targeting host kinases th
38 eding, we hypothesized that a suitable small interfering RNA (siRNA) targeting hepatic FXIII-B could
40 s unaltered in both cells treated with small interfering RNA (siRNA) to Rab5 or Rab7 and cells expres
42 id-polymer nanoparticles encapsulating small interfering RNA (siRNA), for the silencing of genes in b
43 ivo assays were utilized; IRF5 or IRF4 small interfering RNA (siRNA), lentivirus, and conditional kno
45 ing single-guide RNA (sgRNA)/dCas9 and small interfering RNA (siRNA)-mediated protein knockdown, comb
47 ercellular and systemic trafficking of small interfering RNA (siRNA)/microRNA (miRNA) is a central co
48 iopsy supernatants, histamine, PGE2, a small interfering RNA against EP2, or an agonist of F2R like t
49 1l, Ezh2, Kdm5b, and Kdm6b by specific small interfering RNA and Vivo-Morpholino, as well as inhibiti
51 thesized that a mutant allele-specific small interfering RNA could rescue the cellular phenotype in p
53 terference (RNAi) by topically applied small interfering RNA has potential applications for plant fun
54 r the potential use of allele-specific small interfering RNA in treating KID syndrome and other domin
55 es, called carbon dots, for delivering small interfering RNA into the model plants Nicotiana benthami
57 inhibition of VIFs with acrylamide and small interfering RNA knockdown of vimentin significantly decr
59 t with in vivo data, IL-6 knockdown by small interfering RNA or the blockade of IL-6R signaling exace
64 -mediated deletion of Mm47, as well as small interfering RNA studies in mice primary macrophages, sho
68 wice-yearly injection of inclisiran, a small interfering RNA, was shown to inhibit hepatic synthesis
70 iments, we interrogated the effects of short interfering RNA-mediated knockdown of Setd6 in the rat d
74 erimental systems, depletion of G9a by small interfering RNA/short hairpin RNA or inhibition of G9a b
75 wn as mini viral RNAs (mvRNAs) and defective interfering RNAs (DI RNAs) expressed from an IAV minirep
76 Natural antisense transcript-derived small interfering RNAs (nat-siRNAs) are a class of functional
79 sing avenue for drug development, with small interfering RNAs (siRNA) and microRNAs gaining traction
80 opic CHG methylation, as well as 24-nt small interfering RNAs (siRNAs) and histone H3 lysine dimethyl
81 een identified that enhance potency of small interfering RNAs (siRNAs) and that reduce off-target eff
82 ted plants accumulate 21-24 nucleotide small interfering RNAs (siRNAs) derived from viral RNA (virus-
84 ssed by DICER-LIKE3 into 24-nucleotide small interfering RNAs (siRNAs) that guide RNA-directed DNA me
85 circ-MDM2 Knocking down circ-MDM2 with small interfering RNAs (siRNAs) that targeted circ-MDM2 did no
88 lencing specifically in hepatocytes by small interfering RNAs conjugated to triantennary N-acetyl gal
89 nsfected plasmids or knocked down with small interfering RNAs in BE cells and analyzed by immunoblots
93 uity in the signal-decoding process, so that interfering sensor signals due to coincidently-detected
96 get for developing antimicrobial agents that interfere specifically with late-stage P. aeruginosa dev
99 defines an innovative RNA-based strategy to interfere with a pivotal function of the tumor-related l
100 eta-burst TMS to LOC (and a control site) to interfere with an extended window (approximately 30-50 m
105 ed MIF inhibitors, whereas msR4M-L1 does not interfere with cardioprotective MIF/CD74 signaling.
115 further insights on how Plasmodium parasites interfere with erythropoiesis and contribute to anemia i
117 ally, we identify NEMF mutations expected to interfere with function in patients from seven families
119 hemicals (EDCs) are exogenous chemicals that interfere with hormone action, thereby increasing the ri
122 uivalent mutations in yeast Rqc2 selectively interfere with its ability to modify aberrant translatio
124 ked glycosyl residues from these IgG did not interfere with its entry into the podocytes but eliminat
126 r drug-induced DNA-protein crosslinks (DPCs) interfere with key DNA transactions if not repaired in a
127 elative contraindication to FLACS, as it may interfere with laser beam delivery, thus causing unpredi
131 nteraction with the A-site codon to possibly interfere with mRNA movement through the channel and/or
132 nse to Mtb infection and possible avenues to interfere with Mtb infection, including vitamin B5 suppl
135 to endocrine disrupting chemicals (EDCs) may interfere with normal brain development and predispose f
136 learn how the retention of PCNA on DNA might interfere with normal DNA metabolism, we studied the res
139 the KTKEGV repeat domain of alpha-Syn, which interfere with phospholipid binding, are ineffective in
145 hough structurally similar to ES24, does not interfere with SecYEG-dependent protein trafficking.
147 e, our study establishes innovative tools to interfere with STAT3 signaling by different molecular me
151 m154 uses its cytoplasmic tail motif, DD, to interfere with the adaptor protein-1 (AP-1) complex, imp
152 n considerable interest for their ability to interfere with the bacterial communication process refer
153 cal three-dimensional structure, which might interfere with the binding and interaction with the effe
155 ovine serum, identified as albumin, does not interfere with the catalytic activity of soluble recepto
156 ly, adverse effects of cancer therapies that interfere with the continuation of best-possible care, i
157 We posit that PCNA molecules trapped on DNA interfere with the correct metabolism of arrested replic
158 ct kind of person-a way of thinking that can interfere with the development of children's own engagem
159 cts with low nanomolar affinity and does not interfere with the endogenous regulation of C3b depositi
161 ly, and awareness of such knowledge can even interfere with the exploitation thereof.SIGNIFICANCE STA
164 argeting protein palmitoylation in AML could interfere with the leukemogenic potential and block MDSC
165 ZIP), a PKMzeta inhibitor, is widely used to interfere with the maintenance of acquired memories.
166 by effecting changes in host behaviour which interfere with the pathogen's ability to infect and re-i
167 contraception, not on medication that could interfere with the progestogen-only pill, and willing to
172 rowth, and adverse events in childhood might interfere with these processes and have long-lasting eff
173 The screen identified several compounds that interfere with transcription, DNA damage repair and the
176 omoter of the WHI5 inhibitor, or vice versa, interfered with cell size homeostasis, yielding a broade
178 ion coefficient analysis confirmed bilirubin interfered with creatinine, with worsening agreement in
181 wed that losing one of the leucoplast motifs interfered with its function in root leucoplasts but had
184 thalamocortical model, training a new memory interfered with previously learned old memories leading
185 o normal controls, PI3K/mTOR hyperactivation interfered with primary cilia assembly (scenario also ob
186 n addition, we found that activation of PKM2 interfered with TGF-beta1 signaling, which is necessary
188 udies revealed that D/N Vif mutants directly interfered with the association of CBFbeta and wild-type
189 ith a dominant-negative (D/N) phenotype that interfered with the function of wild-type Vif, inhibited
190 A inhibited PEPCK-M enzyme activity as 3-MPA interfered with the PEPCK enzyme assay, particularly at
192 decline in 1 or more cognitive domains that interferes with a person's independence in daily activit
193 um by transcription of upstream lncRNAs that interferes with activation of the flanking mRNA promoter
194 or-binding area suggested that glycosylation interferes with APOE's attraction to receptors, lipid-bi
198 ce between capsid protein monomers, where it interferes with capsid-protein-mediated interactions bet
199 y, we identify that the deubiquitinase USP36 interferes with degradation of PrimPol to regulate the r
200 vide a mechanism by which TDP-43 dysfunction interferes with dendritic branching, and may define path
201 s the first study to show that pembrolizumab interferes with differentiation of human FOXP3(+) iTregs
206 , the mechanisms by which the stress pathway interferes with host response to pathogens remain unclea
208 n alters the conformation of the amide bond, interferes with hydrogen bond formation, and changes oth
209 Mutant HTT (mHTT) disrupts transcription, interferes with immune and mitochondrial function, and i
210 ose infection with the drug tenofovir, which interferes with initial infection, and atazanavir, which
211 viously shown that Arid1b haploinsufficiency interferes with interneuron development and leads to soc
212 e mutants of GRAF1/2, WDR44, and MICAL1 also interferes with it, facilitating future studies of Rab8/
214 whether exposure to fine particulate matter interferes with lung recovery and remodeling in a murine
215 In this work, we show that IFN signaling interferes with lung repair during influenza recovery in
216 dorsal hippocampus and that SETD6 knockdown interferes with memory consolidation, alters gene expres
219 we describe a pharmacological strategy that interferes with Notch signaling by disrupting the Notch
220 the interaction between CLOCK and BMAL1 and interferes with nuclear translocation of CLOCK both in v
221 C) is one of the most painful cancers, which interferes with orofacial function including talking and
222 novel pharmacologic combination therapy that interferes with PAX3-FOXO1 biology at different levels.
224 a suggest that Pol II transcription robustly interferes with Pol III function at specific tRNA genes.
226 FBP1 inhibits glycolysis but also directly interferes with PRC2 function, thus FBP1 and PRC2 are pa
231 vation of p38 MAPK in high glucose condition interferes with Src-extracellular signal-regulated kinas
232 early activation of natural killer cells and interferes with subsequent adaptive immune cell recruitm
233 have demonstrated that chronic inflammation interferes with T-cell response and macrophage function
235 (-)), a central intermediate of the N-cycle, interferes with the electrochemical determination of the
236 at distal regions, suggesting that neoGATA3 interferes with the fine tuning of ER-dependent gene exp
238 ght to impact many vital brain functions and interferes with the genesis and/or progression of numero
239 hat deletion of the conserved alpha-helix 30 interferes with the integrity of the cell wall, disrupts
241 ts with the PYR1/PYL/RCAR and PP2C proteins, interferes with the interaction between PYR1/PYL4 and AB
242 lycosylated single-transmembrane sialomucin, interferes with the interactions between inflammatory ce
243 These results suggest that TA distinctly interferes with the lipid signaling and metabolism of PC
244 Yen1, showing that its premature activation interferes with the response to perturbed replication.
245 nistic studies in vitro showed that neoGATA3 interferes with the transcriptional programs controlled
248 For other ligands, selectivity is caused by interfering with a water molecule that binds more strong
251 heRS, this toxicity of m-Tyr may result from interfering with amino acid metabolism, destabalizing a
252 sion of major histocompatibility complex and interfering with antigen presentation in murine models a
255 ouble up as ubiquitin hydrolases (DUB), thus interfering with cellular processes critical for virus r
260 fficacious in the joint but not the gut, and interfering with gut trafficking by targeting molecules
262 igger escape from dormancy of microtumors by interfering with inflammation resolution and triggering
263 discusses the different strategies aimed at interfering with its biologic activity as well as their
264 enesis by physically interacting with Ascl1, interfering with its DNA binding and limiting neurogenes
270 AF-16 modulates mitochondrial homeostasis by interfering with mitochondrial dynamics and mitophagy.
272 inhibition of de novo lipid biosynthesis by interfering with nematode ACC is a new nematicidal mode
274 alter the dynamics of a viral population by interfering with normal virus replication and/or by stim
275 thus highlight the therapeutic potential of interfering with osteoclast-intrinsic metabolic pathways
276 ally persist beyond the acute disease stage, interfering with patients' recovery and quality of life.
277 the Set3C complex, recruiting RNA pol II and interfering with Rap1 binding to activate genes in other
278 as the former prevent cell-cycle entry, thus interfering with S-phase- or mitosis-targeting agents.
280 medium reacted quickly both with GO and MGO, interfering with the antibacterial potential and the deg
281 obably confers a dominant negative effect by interfering with the branching-inhibitory BRC1 genes.
282 e prevents at least some viral infections by interfering with the interaction of the virus with its r
283 agonists, and proteasome inhibitors without interfering with the known mechanism of action of these
289 een parental and offspring environments, and interfering with the transmission of parental cues to of
290 ai virus and respiratory syncytial virus) by interfering with the virus-induced cellular autophagy pa
291 under oxidizing conditions, thus potentially interfering with their ability to bind to MHC molecules.
292 ehavior in the association task, potentially interfering with their ability to generate group consens
295 ity and promote viral dissemination and that interfering with these processes might reduce the likeli
297 olytic maturation of insulin proreceptors by interfering with transport of newly synthesized insulin