ライフサイエンスコーパス: intergenerational

1 s a range of ESP conditions, maintaining the intergenerational ability to alternate habitats.

2 e, we investigate four independent models of intergenerational adaptations to stress in Caenorhabditi

3 across India, with strong preference towards intergenerational and community care.

4 Our results reveal increased intergenerational and somatic instability of the HD CAG

5 seen an explosion of studies documenting the intergenerational and transgenerational effects of envir

6 Here, we show intergenerational and transgenerational inheritance of t

7 We highlight essential definitions of intergenerational and transgenerational transmission of

8 t instability and fragmentation on seasonal, intergenerational, and evolutionary time scales.

9 le protein content across transgenerational, intergenerational, and third-generation stress memory st

10 We identify an intergenerational association between maternal exposure

11 The data also showed an intergenerational association of FM between mothers and

12 PA and FM in adolescents and to describe the intergenerational association of FM between mothers and

13 Intergenerational association of PTSD is clearly present

14 characteristics of both parents confound the intergenerational association.

15 Here, we use metabolomics to investigate the intergenerational biochemical signatures associated with

16 yzed Illinois vital records to determine the intergenerational birth weight patterns among the descen

17 We have detected intergenerational CAG repeat instability in transgenic m

18 e temporal and geographical implications for intergenerational caregiving.

19 We prospectively examined intergenerational change in BMI and tested the fetal ove

20 genes that exhibited a greater than twofold intergenerational change in expression in all four speci

21 genes that exhibited a greater than twofold intergenerational change in expression in response to st

22 The frequency of intergenerational changes was age dependent for both pat

23 ted cloning via artificial nuclear transfer; intergenerational clonality in nature via parthenogenesi

24 forge interdisciplinary, international, and intergenerational collaborations on behalf of the cultur

25 is redefining the tenets of inter-organ and intergenerational communications.

26 Intergenerational conflict combined with the known benef

27 estriction in a parent's fetal life can have intergenerational consequences in human populations.

28 s but also the associated, often-overlooked, intergenerational consequences of these deaths.

29 activation of the maternal HPA axis can have intergenerational consequences via, for example, materna

30 d health system capacity coupled with closer intergenerational contact largely negates this benefit.

31 ological standards provided evidence for the intergenerational continuity of child physical abuse, bu

32 ed anticipation is sometimes associated with intergenerational contraction rather than expansion of t

33 In fact, despite a higher prevalence of intergenerational coresidence and contacts that is broad

34 ed populations and relatively high levels of intergenerational coresidence, are, all else equal, the

35 n countries with small households and little intergenerational coresidence, such as France, whereas c

36 the highest number of CpGs with significant intergenerational correlation in DNAm, with 1829 CpGs (0

37 Here, we report an intergenerational correlation in reproductive success in

38 but in asthmatic families a major element of intergenerational correlation is associated with a mater

39 role of the shared environment in explaining intergenerational correlations in birth weight and lengt

40 cant shared-environment contributions to the intergenerational correlations were identified in biomet

41 moderately but significantly contributes to intergenerational correlations.

42 on and local resource enhancement, while the intergenerational cost to immigration is a new complicat

43 teractions about math at home help break the intergenerational cycle of low math achievement.

44 udies that explore mechanisms underlying the intergenerational cycle of obesity are warranted to iden

45 promote women's rights could help break the intergenerational cycle of undernutrition through many r

46 urished parents, and these may contribute to intergenerational cycles of malnutrition.

47 cash transfers have the potential to reduce intergenerational cycles of poverty-related educational

48 onutrient malnutrition and can interrupt its intergenerational debilitating effects on national devel

49 ession, which may contribute to lifelong and intergenerational deficits in growth and development.

50 n mind when making collective decisions, the intergenerational depth of people's obligation and conce

51 In an intergenerational developmental programming model affect

52 educational programmes and enable respectful intergenerational dialogue to foster a stigma-free futur

53 ds, reshaped land- and seascapes, threatened intergenerational ecological knowledge transfer, and led

54 a psychological perspective to the issue of intergenerational economic mobility.

55 eration database was constructed to quantify intergenerational educational mobility.

56 ver the mechanisms underlying the direct and intergenerational effect of adiposity on DNA methylation

57 We examined the intergenerational effect of maternal CM exposure on chil

58 The intergenerational effect of treatment was considerable:

59 While this intergenerational effect was not passed down to the F2 g

60 Instead, we found a TNF-alpha-dependent intergenerational effect, as mothers with a deficit in T

61 sting that presumed adaptive and deleterious intergenerational effects are molecularly related at the

62 nity during which substantial life cycle and intergenerational effects can be accrued.

63 wever, the proximate mechanisms behind these intergenerational effects have remained elusive.

64 Emerging evidence on the role of intergenerational effects in determining maternal precon

65 r research is warranted on the long-term and intergenerational effects of antenatal supplementations.

66 Thus the intergenerational effects of gestational SS involve epig

67 Here, we test the direct effects and intergenerational effects of jasmonic acid (JA) treatmen

68 hether this system should be maintained, the intergenerational effects of mass incarceration, and str

69 We investigated intergenerational effects of maternal CM on DNA methylat

70 We note that food instability might have intergenerational effects on birds: Nutritional stress d

71 er association in mothers is consistent with intergenerational effects on intrauterine growth and wit

72 d stress was measured to determine potential intergenerational effects on the children's functioning

73 Whether early life adversity also imposes intergenerational effects on the exposed individual's of

74 w severe psychophysiological trauma can have intergenerational effects.

75 y, revealing a placental origin of mammalian intergenerational effects.

76 ting tsRNA biogenesis, and together transmit intergenerational effects.

77 icular interest because of the potential for intergenerational epigenetic effects.

78 ial in developing a greater understanding of intergenerational epigenetic inheritance.

79 ngs indicated that genetic variances were in intergenerational equilibrium.

80 ions Paris Agreement, and makes questions of intergenerational equity into explicit design choices.

81 peats, and Dnmt1 deficiency in mice promoted intergenerational expansion of CAG repeats at the murine

82 Fourthly, both ePAL and the intergenerational expansion size were significantly asso

83 .4%, respectively, of HD families with large intergenerational expansions.

84 dynamics, with A2 and C showing the largest intergenerational expansions.

85 ng-rooted experience, including familial and intergenerational experiences of food insecurity: "I gre

86 the fourth decade of life is associated with intergenerational factors and various aspects of people'

87 Research on intergenerational factors that might also predispose a c

88 to variation in parental nutrition, to shape intergenerational fitness responses.

89 We use a laboratory version of the intergenerational goods game (IGG) to investigate whethe

90 we devise a new experimental paradigm, the 'Intergenerational Goods Game'.

91 An intergenerational group of MPRCA women and allies met to

92 s in the maternal microbiome just before the intergenerational hand-off of the microbiota.

93 ovide evidence for genetic modifiers of both intergenerational HD CAG repeat instability and striatal

94 tween paternal preconception environment and intergenerational health in mice.

95 However, to date, mechanisms underlying intergenerational heart disease risks have yet to be elu

96 nature via parthenogenesis and gynogenesis; intergenerational hemiclonality via hybridogenesis and k

97 a greater impact in countries with large and intergenerational households, such as Bangladesh.

98 ramming in the early origins of obesity, but intergenerational human data are lacking.We prospectivel

99 We sought to test an intergenerational hypothesis, that the childhood SES tha

100 the duration of exposure when assessing the intergenerational impacts of paternal health.

101 Influence of intergenerational in utero parental energy and nutrient

102 Recent research suggests that intergenerational income mobility has remained low and s

103 fic influence from fetal environment on this intergenerational increase in adult obesity.

104 characterized by genetic anticipation or the intergenerational increase in disease severity accompani

105 several spinocerebellar ataxias, result from intergenerational increases in the length of a CTG.CAG r

106 g that geography is pivotal to understanding intergenerational inequalities.

107 Few data exist on the intergenerational influence of calcium intake during pre

108 ults also highlight an apparent long-lasting intergenerational influence of maternal BMI on offspring

109 l and dietary effects on oral health, and 5) intergenerational influences on oral health.

110 stnatal growth appears to be under patriline intergenerational influences.

111 in offspring, but mechanisms underlying such intergenerational information transfer remain obscure.

112 y toward expansions over contractions during intergenerational inheritance compared to those in homoz

113 paternal epigenetic factor that may mediate intergenerational inheritance of diet-induced metabolic

114 Furthermore, we find that intergenerational inheritance of lipotoxic cardiomyopath

115 e loci cannot participate in such a chain of intergenerational inheritance.

116 These intergenerational instabilities increased in frequency a

117 xon 1 with 48 CAG repeats revealed only mild intergenerational instability ( approximately 2% of meio

118 We have observed a high intergenerational instability (46.3%+/-5.1%) of the larg

119 We have detected intergenerational instability and age-related somatic in

120 C transgenic mice with CAG 45 alleles reveal intergenerational instability at an overall rate of appr

121 Intergenerational instability has been described in all

122 As with hairpins, triplex mediates intergenerational instability in 96% of transmissions.

123 ats of certain trinucleotides show extensive intergenerational instability in humans that is associat

124 during germline development contributing to intergenerational instability of CAG repeats in mice and

125 This mechanism involves the expansion and intergenerational instability of stretches of consecutiv

126 ypes in these three genetic backgrounds: the intergenerational instability of the HD CAG repeat and t

127 +) SCA1 counterparts, closely reproduced the intergenerational instability patterns observed in human

128 ic fragment transgenic mice displayed marked intergenerational instability with an obvious expansion

129 repeats at the molecular level: somatic and intergenerational instability, fragility, and repeat-ind

130 this multifamily study, we investigated the intergenerational instability, somatic and germline mosa

131 (HD) gene exhibit striking length-dependent intergenerational instability, typically small size incr

132 e development and that vitellogenin-mediated intergenerational insulin/IGF-to-insulin/IGF signaling m

133 of individual brains, intragenerational and intergenerational interacting brains, social constructs,

134 on of local and national contexts as well as intergenerational interactions.

135 ns over climate change, pandemics, and other intergenerational issues mount, the call for intergenera

136 dylinositol signaling pathway as a target of intergenerational JA effects.

137 d telomere shortening, at the individual and intergenerational levels.

138 inistration of M. vaccae ATCC 15483(T) in an intergenerational manner is protective against the negat

139 ulates loss of TET1, and provide a potential intergenerational mechanism for adjusting fecundity to e

140 Given these intergenerational mechanisms and physical aggression ons

141 onary theory by bringing together intra- and intergenerational mechanisms of phenotypic plasticity an

142 uncovered nuanced changes that increased the intergenerational memory of phenotypic resistance.

143 erns were highly age-assortative, with clear intergenerational mixing between household members.

144 numbers (11.56, SD 0.23) and percentages of intergenerational mixing with older adults (7.5% of cont

145 Growing up in a county with 1 SD better intergenerational mobility accounts for approximately 20

146 Chetty and Hendren's county-level measure of intergenerational mobility and children's cognitive and

147 s both structural deprivation and associated intergenerational mobility and colourism (ie, implicit a

148 Intergenerational mobility declined substantially over t

149 ies, such that countries with high levels of intergenerational mobility have weaker associations of f

150 ironmental differences underlie variation in intergenerational mobility, and that there is no tension

151 nomic activity restructures the landscape of intergenerational mobility, but factors associated with

152 In societies with high intergenerational mobility, less variance in educational

153 A large literature documents how intergenerational mobility-the degree to which (dis)adva

154 opportunity, social scientists have studied intergenerational mobility-the degree to which children'

155 rior to mating would be sufficient to induce intergenerational modifications of anxiety-related behav

156 ology is not sufficient to implicate them as intergenerational neural mediators.

157 Here we highlight recent intergenerational neuroimaging studies and provide recom

158 We tested the hypothesis that intergenerational, non-genetic heritable effects influen

159 nd adult BAT, uncovering an oocyte origin of intergenerational obesity.

160 age with weight management in order to halt intergenerational obesity.

161 Intergenerational occupational rank-rank correlations in

162 nce supporting the important contribution of intergenerational parental stress in offspring neurodeve

163 Here we dissect the intergenerational path taken by dsRNA from parental circ

164 onal life course approaches may help disrupt intergenerational pathways to the criminal legal system.

165 ults suggest that Americans overestimate the intergenerational persistence in income ranks.

166 lease and limited dispersal of symbionts for intergenerational persistence of mutualisms.

167 e potential for sex to influence patterns of intergenerational plasticity and raise new questions abo

168 se new questions about the interface between intergenerational plasticity and sex-specific selective

169 n important role in driving the evolution of intergenerational plasticity in both adaptive and non-ad

170 Intergenerational plasticity or parental effects-when pa

171 sin, only after at least 5000 years were the intergenerational potentials of material wealth transmis

172 r only a single, recent generation, ignoring intergenerational preconditions and historical confermen

173 demiological studies indeed evidence such an intergenerational predisposition to surgical delivery.

174 Strategies preventing the intergenerational propagation of effects of stress would

175 In a record-linked, intergenerational prospective study from the general pop

176 for policy interventions designed to sustain intergenerational public goods.

177 aicism that can potentially cause unexpected intergenerational recurrences.

178 ese women, however, there has been a tenfold intergenerational reduction in smoking uptake rates.

179 a common genetic liability accounted for the intergenerational relations.

180 ing potentially significant consequences for intergenerational relationships and caregiving.

181 m is to reflect on the possible link between intergenerational relationships and spread and lethality

182 nce nor the absence of a causal link between intergenerational relationships and the severity of COVI

183 We conclude by arguing that intergenerational relationships are not only about physi

184 Theoretically, different forms of intergenerational relationships may have causal effects

185 mographic factors, such as age structure and intergenerational relationships.

186 tability has compromised attempts to measure intergenerational repeat dynamics and infer genotype-phe

187 Although the basis for intergenerational repeat expansion is unclear, repeat tr

188 ations display earlier disease onsets due to intergenerational repeat expansion.

189 ing epigenetic reprogramming may trigger the intergenerational repeat expansions that lead to disease

190 Mice heterozygous for the CAG expansion show intergenerational repeat instability (+2 to -6) at a muc

191 We discuss the reasons for gender bias in intergenerational repeat instability and the tissue spec

192 ion of small changes, are reminiscent of the intergenerational repeat instability observed in human p

193 characterized by marked anticipation due to intergenerational repeat instability with a bias toward

194 While the cDNA transgenic mice showed little intergenerational repeat instability, the genomic fragme

195 However, intergenerational resource transfers and other late-life

196 In human societies, intergenerational resource transfers, for example, food

197 ensive microbial archiving becomes an urgent intergenerational responsibility.

198 The authors conclude that the expected intergenerational rise in birth weight does not occur am

199 nd promoting parenting skills can reduce the intergenerational risk of excess childhood adiposity and

200 etoxification, beta-cyanoalanine, acts as an intergenerational signal to protect progeny from infecti

201 We use data on intergenerational social mobility by neighborhood to exa

202 y of persons from farm origins, we find that intergenerational social mobility has been remarkably st

203 1850 to 2015 to document long-term trends in intergenerational social mobility in the United States.

204 circumstances had shorter telomeres, as was intergenerational social mobility, but not accumulated d

205 New evidence shows that intergenerational social mobility-the rate at which chil

206 Pedigree analysis of the intergenerational stability of alleles of this haplotype

207 regulator of SE degradation, which improves intergenerational sterol transfer and reproductive succe

208 intergenerational issues mount, the call for intergenerational stewardship resounds in psychology, et

209 rse sample (n = 147) from the Programming of Intergenerational Stress Mechanisms (PRISM) study (Massa

210 an ongoing cohort study, the Programming of Intergenerational Stress Mechanisms (PRISM) Study, based

211 over the domestic cycle are smoothed by the intergenerational structure of complex households and ex

212 Here, we report a direct measurement of the intergenerational substitution rate in the human CR.

213 s wealth: over the short run, the life span, intergenerational succession, and in (legal) perpetuity

214 opose that an 'undernourished' microbiome is intergenerational, thereby perpetuating growth impairmen

215 Policies should also take into account that intergenerational ties are a source of instrumental and

216 products from EW from soils, offering CDR on intergenerational timescales.

217 nerations in the worm Caenorhabditis elegans Intergenerational transfer of dsRNA occurs even in anima

218 Although it is unclear how such intergenerational transfer of information occurs, RNAs f

219 tential for early intervention to reduce the intergenerational transfer of obesity.

220 Intergenerational transfer of wealth has been proposed a

221 transfer at the expense of reduced vertical (intergenerational) transfer and vice versa, a key trade-

222 ever, successful reproduction often involves intergenerational transfers as well as fertility.

223 Previous work has shown formally that intergenerational transfers can explain both these patte

224 a unique framework to test the importance of intergenerational transfers of wealth in driving sibling

225 fertility (the classic effect) and remaining intergenerational transfers to be made to others.

226 GAA*TTC)n sequence, which is unstable during intergenerational transmission and in most patient tissu

227 The repeats expand both somatically and on intergenerational transmission and increased repeat numb

228 he population level, norms are influenced by intergenerational transmission and the structure of the

229 Although the intergenerational transmission between parental psychiat

230 genetic risk, however, confounds the entire intergenerational transmission in female offspring.

231 However, it remains unknown whether this intergenerational transmission is attributable to broade

232 We address the hypothesis that intergenerational transmission may begin during intraute

233 ver-represented in caregivers, with possible intergenerational transmission of abnormal illness behav

234 The extent of the intergenerational transmission of abuse and neglect depe

235 A three-generation longitudinal study of the intergenerational transmission of abuse is also highligh

236 which the effects of early experience on the intergenerational transmission of abusive parenting are

237 ial, the design of studies investigating the intergenerational transmission of child physical abuse.

238 c and environmental processes underlying the intergenerational transmission of childhood conduct prob

239 In newborns, we found no evidence for any intergenerational transmission of CM-related methylation

240 The mechanisms underlying the intergenerational transmission of conduct problems depen

241 n and measured covariates indicated that the intergenerational transmission of conduct problems for m

242 In contrast, the intergenerational transmission of conduct problems was n

243 xposed to prenatal depression, interrupt the intergenerational transmission of depression, and ultima

244 resent the current state of knowledge on the intergenerational transmission of diabetes from epidemio

245 perpetuates health inequalities through the intergenerational transmission of disadvantage.

246 arental genetic influences contribute to the intergenerational transmission of educational outcomes,

247 a paucity of data from human populations on intergenerational transmission of environmentally induce

248 Although the potential intergenerational transmission of epigenetic changes nee

249 Mechanistic examination of modes of intergenerational transmission of exposure during pregna

250 ted States, one that could contribute to the intergenerational transmission of health disadvantage.

251 vanced neuroimaging methods to elucidate the intergenerational transmission of human brain circuitry.

252 ed the role of monoaminergic function in the intergenerational transmission of infant abuse in rhesus

253 These results suggest that the intergenerational transmission of infant abuse in rhesus

254 es of maternal rejection plays a role in the intergenerational transmission of infant abuse.

255 t vitellogenin as a likely key player in the intergenerational transmission of information.

256 minant of human behavior and health, and the intergenerational transmission of knowledge regarding th

257 ed sources of information, leading to stable intergenerational transmission of knowledge.

258 entifying brain mechanisms implicated in the intergenerational transmission of major depressive disor

259 The strongest evidence for the intergenerational transmission of maltreatment indicates

260 early in pregnancy as possible to reduce the intergenerational transmission of metabolic disease.

261 ically well-defined Finnish families showing intergenerational transmission of migraine with aura (MA

262 uss the urgent need and challenges to reduce intergenerational transmission of obesity and diabetes.

263 medicine, and this may lead to prevention of intergenerational transmission of obesity and type 2 dia

264 A study by Akimova et al. finds that most intergenerational transmission of occupational status ca

265 sperm maturation, can also perform roles in intergenerational transmission of paternal environmental

266 for their children, thus contributing to the intergenerational transmission of poverty.

267 future multidisciplinary work examining the intergenerational transmission of psychiatric risk throu

268 nd function, host metabolic expenditure, and intergenerational transmission of risk (including epigen

269 Identifying mechanisms underlying the intergenerational transmission of risk for attention-def

270 ure effects are particularly relevant to the intergenerational transmission of risk for child educati

271 nown about the mechanisms through which this intergenerational transmission of risk occurs.

272 ng longstanding cultural continuities in the intergenerational transmission of shared knowledge on la

273 been widely discussed as mechanisms to curb intergenerational transmission of socioeconomic disadvan

274 ial pathophysiologic pathway involved in the intergenerational transmission of socioeconomic inequali

275 The involvement of epigenetic mechanisms in intergenerational transmission of stress effects has bee

276 Although we did not observe evidence of intergenerational transmission of the DNAm change, large

277 These observations support our hypothesis of intergenerational transmission of the effects of materna

278 e 3' genomic region significantly stabilized intergenerational transmission of the SCA7 CAG92 repeat.

279 anation for some of these differences is the intergenerational transmission of this disorder due to s

280 We estimate the degree of intergenerational transmission of three different types

281 l PTSD suggests different mechanisms for the intergenerational transmission of trauma-related vulnera

282 We show that intergenerational transmission of wealth and wealth ineq

283 l aggression are generally the product of an intergenerational transmission process occurring through

284 Intergenerational transmission studies suggest that thes

285 ying a potential novel biological pathway of intergenerational transmission that may operate as early

286 The magnitude of the intergenerational transmission was significant for all o

287 on offspring, a concept we refer to here as 'intergenerational transmission', via changes to gametes

288 h the repeat locus is highly unstable during intergenerational transmission, it remains unknown wheth

289 od malnutrition, including the potential for intergenerational transmission, remain unexplored.

290 sex-specific changes in allele length during intergenerational transmission.

291 nstable, with frequent length changes during intergenerational transmission.

292 ion and cognition, and limited potential for intergenerational transmission.

293 n repeat predisposes it to expansions during intergenerational transmissions leading to fragile X syn

294 d, the molecular mechanisms underlying these intergenerational transmissions remain elusive, though r

295 cells, albeit on a smaller scale than during intergenerational transmissions.

296 ommission (TRC) in Canada to acknowledge the intergenerational trauma and mistrust toward colonial in

297 Extrapolations of intergenerational variance in spatial position (sigma(2)

298 ed cohort study, individuals who experienced intergenerational welfare contact represented one-third

299 arent-only welfare contact, individuals with intergenerational welfare contact were more disadvantage

300 example, the proportion of individuals with intergenerational welfare contact who had experienced at