ライフサイエンスコーパス: interindividual

1 dual) and among the bulbs of different mice (interindividual).

2 compaction of meiotic chromosomes, generates interindividual and cell-to-cell variation in diverse me

3 d with clearance (P < 0.01), explaining both interindividual and interoccasional variability.

4 Although genetic factors contribute to interindividual and interpopulation variation in reprodu

5 Ten studies that examined interindividual and intraindividual patterns of activity

6 r a control diet for 12 weeks to investigate interindividual- and sex-specific variations in the deve

7 Interindividual clinical variability in the course of se

8 ocyte activation status, contributing to the interindividual complexity of immune responses.

9 ns in climate, influenza-like illnesses, and interindividual contacts jointly explain IPD seasonality

10 Mean intra- and interindividual CVs were 20% and 25%, respectively.

11 rom the whole-body examinations by automated interindividual deformable image registration of the wat

12 ers, but the neurogenetic mechanisms driving interindividual differences are largely unknown.

13 Whether these interindividual differences are mirrored by idiosyncrati

14 orneal staining and TBUT are associated with interindividual differences but not intraindividual chan

15 span and life span require understanding of interindividual differences in age-dependent functional

16 ion differentially drive intraindividual and interindividual differences in altruistic behavior.

17 serotonin receptor genes, were predictive of interindividual differences in anxiety-like behavior.

18 Finally, interindividual differences in brain activity relate to

19 elevant to dietary choice; 2) characterizing interindividual differences in chemosensory function and

20 A compartmental model that allowed for interindividual differences in cis- and all-trans-lycope

21 onship informs about the biological basis of interindividual differences in cognitive control.

22 individuals into 2 distinct groups based on interindividual differences in concentrations of differe

23 EBA); activity in the PMv moreover reflected interindividual differences in congruent arm ownership.

24 ggesting that quantitating and understanding interindividual differences in DNA repair capacity (DRC)

25 g substrates with important implications for interindividual differences in efficacy and toxicity.

26 diverse downstream effects that manifest as interindividual differences in efficacy, adverse effects

27 lutamine (Gln), GABA or their ratios predict interindividual differences in effort-based motivated ta

28 The first-principles model better quantifies interindividual differences in food intake, shows how as

29 ask-based fMRI data, these two DCS predicted interindividual differences in frequency of behavioral l

30 igenetic mechanisms that are associated with interindividual differences in gene expression in brain

31 her candidate genes that are associated with interindividual differences in humoral immunity to rubel

32 dy how experience and genetics contribute to interindividual differences in learned song.

33 idual variability in GABA level is linked to interindividual differences in many aspects of visual pe

34 of plasma CK-M and CA-3 revealed changes and interindividual differences in muscle tissue proteome dy

35 sms in HLA-DPB1 are strongly associated with interindividual differences in neutralizing antibody lev

36 h the host genetic background contributes to interindividual differences in other determinants of HIV

37 euron excitability and thereby contribute to interindividual differences in pain in other families, t

38 ional brain connectome that is predictive of interindividual differences in pain sensitivity.

39 subject-specific iPSCs can be used to model interindividual differences in pain.

40 modulates pain signaling and contributes to interindividual differences in pain.

41 at modulate pain signaling and contribute to interindividual differences in pain.SIGNIFICANCE STATEME

42 in peripheral sensory neurons contribute to interindividual differences in pain; and third, using wh

43 in peripheral sensory neurons contribute to interindividual differences in pain; and third, using wh

44 This relationship occurred independently of interindividual differences in preferential facial infor

45 Linking interindividual differences in psychological phenotype t

46 provided anatomically specific evidence that interindividual differences in response speed is associa

47 n glucagon secretory responses contribute to interindividual differences in response to SGLT2 inhibit

48 However, large interindividual differences in responses to rTMS have be

49 Interindividual differences in resulting plasma concentr

50 ked activity in the pre-SMA was predicted by interindividual differences in risk-aversion attitudes e

51 Interindividual differences in sensitivity to evening li

52 Thus, our findings suggest a link between interindividual differences in sensorimotor speed and se

53 f parietal and occipital cortices related to interindividual differences in size, orientation, and br

54 Interindividual differences in such positive and negativ

55 rks (Delta connectivity lFPN-rFPN) predicted interindividual differences in task performance more acc

56 Interindividual differences in the amplitude of this ele

57 "compensation" for underlying genetic-driven interindividual differences in the baseline chromatin an

58 We found large interindividual differences in the degree of model-based

59 etic and environmental influences explaining interindividual differences in the developmental course

60 ance imaging and tractography, could explain interindividual differences in the effects of rTMS.

61 We show that interindividual differences in the extension of the PPS

62 dence also suggests a potential link between interindividual differences in the gut microbiota and va

63 Interindividual differences in the linear change in hype

64 ange in representational similarity predicts interindividual differences in the malleability of subje

65 This new evidence hints that interindividual differences in the microbiome may accoun

66 Traditionally, interindividual differences in the population are accoun

67 Previous work has shown high interindividual differences in the susceptibility to the

68 Capturing interindividual differences in the translated genome wil

69 Moreover, AhR-deficient mice had higher interindividual differences in their microbiome.

70 amyloid biomarker measurements may be due to interindividual differences in total amyloid-beta produc

71 We found large interindividual differences in TSP responses, which were

72 als, and this variability is associated with interindividual differences in visual perception.

73 occur periodically in each brain, or marked interindividual differences that may persist throughout

74 Although interindividual differences were detected, animals prese

75 tive enhancement has neglected the effect of interindividual differences, such as traits, on stimulat

76 n toward the periphery in presence of marked interindividual differences.

77 y explain 18.7% of the variation seen in the interindividual distance of microbial composition.

78 tions of Rome and were accompanied by marked interindividual diversity, reflecting gene flow from acr

79 ol is an oral anticoagulant with significant interindividual dose variations.

80 function, which would be expected to affect interindividual drug disposition and response.

81 n time-dependent activities were considered, interindividual (e.g., adult vs toddler) variability was

82 Interindividual eGFR decline was highly variable but in

83 origins and molecular mechanisms underlying interindividual epigenetic variability remain unknown.

84 Like genetic variants, systemic interindividual epigenetic variants are stable, can infl

85 ure population-based investigations into how interindividual epigenetic variation modulates risk of d

86 Interindividual epigenetic variation that occurs systemi

87 Genes exhibiting high interindividual expression variation include disease can

88 proportion of variance in cancer risk due to interindividual genetic differences) with follow-up via

89 Our results provide evidence for interindividual genetic exchange and recombination in A.

90 Subtle interindividual genetic variation as well as viral and e

91 transposition of chimeric RNA contributes to interindividual genetic variation.

92 Unlike alpha-diversity, interindividual gut microbiome taxonomic (mean -0.11; 95

93 Unlike alpha-diversity, interindividual gut microbiome taxonomic (mean, -0.11 [9

94 Interindividual heterogeneity in drug response is a cent

95 tic variations in CYP2D6 are responsible for interindividual heterogeneity in drug response that can

96 xtual measures (i.e., the share of the total interindividual heterogeneity in health that appears at

97 ining false positives is exacerbated by wide interindividual heterogeneity in microbiota composition(

98 gression analyses likely conceal substantial interindividual heterogeneity in postdeployment alcohol-

99 We hypothesized that interindividual heterogeneity in SGLT2 expression and re

100 Interindividual heterogeneity in the disease progression

101 Interestingly, significant interindividual heterogeneity in VWF glycan expression w

102 al blood, with an ultimate goal of examining interindividual heterogeneity of endothelial biology.

103 aracterizing brain ageing, we also evaluated interindividual heterogeneity within morphometric networ

104 ples analyzed, and the results revealed high interindividual heterogeneity, with most of the reactivi

105 activation associated with LV scar with high interindividual heterogeneity.

106 nisms might be involved in the regulation of interindividual lipid level variability and thus may con

107 ortening during adulthood to offset the wide interindividual LTL variation established prior to adult

108 However, the impact of interindividual navigation ability and demographic risk

109 Their interindividual pharmacokinetic variability is remarkabl

110 These loci explained up to 66% of interindividual plasma protein-level variation and, on a

111 In mice and humans, there is a wide interindividual range in Treg frequency, but little is k

112 For 32 g oil, the interindividual rank order of the chylomicron AUCs was c

113 ion rates were noted to be equivalent to FIV interindividual rates.

114 Longitudinal results substantiated these interindividual relations and further showed intraindivi

115 Interindividual reproducibility was observed down to the

116 Accumulating evidence about variable interindividual response to dietary intake of these caro

117 ysine 170 (K170) of MDV CHPK is required for interindividual spread and autophosphorylation of CHPK a

118 in chickens, CHPK is absolutely required for interindividual spread from chicken to chicken.

119 only reduce tumor formation but do not block interindividual spread from chicken to chicken.

120 Understanding MDV interindividual spread provides important information fo

121 However, it is required for interindividual spread, and mutation of the invariant ly

122 understanding of this important gene during interindividual spread.

123 t information on the requirement of CHPK for interindividual spread.IMPORTANCE Marek's disease in chi

124 develop personalized toxicology to determine interindividual susceptibility to adverse drug reactions

125 ameters incompletely account for substantial interindividual susceptibility to CCM.

126 gate the genetic architecture underlying the interindividual TGP variability, we conducted a genome-w

127 th the magnitude of and molecular causes for interindividual toxicodynamic variability.

128 oxicity of PERC and the degree of associated interindividual toxicokinetic (TK) and toxicodynamic (TD

129 an approach to study the susceptibility and interindividual variabilities in the pathogenesis of non

130 -daily regimens showed substantially reduced interindividual variability and lower median (interquart

131 Interindividual variability and sexual dimorphisms in th

132 To better understand the interindividual variability associated with the majority

133 urther refinement of the characterization of interindividual variability can be accomplished by incor

134 However, marked interindividual variability exists in the degree to whic

135 Substantial interindividual variability exists in the maximal rate o

136 However, there is a considerable degree of interindividual variability for these outcomes, likely d

137 l was to investigate processes that underlie interindividual variability in age-related changes in th

138 The results demonstrate large interindividual variability in alpha-carotene conversion

139 ults reveal a neurogenetic pathway mediating interindividual variability in anticipatory responses to

140 ion serial reversal procedure to investigate interindividual variability in behavioral flexibility in

141 used to calculate adjustment factors for the interindividual variability in both TK and TD.

142 oid signalling pathway may contribute to the interindividual variability in clinical response to ICS

143 nts in the final intron PLPP3 associate with interindividual variability in coronary artery disease r

144 Interindividual variability in dopamine function may res

145 We addressed this issue by examining interindividual variability in dopamine release at rest

146 However, interindividual variability in fecal menaquinone concent

147 ed intake, which is likely mediated via wide interindividual variability in flavonoid absorption and

148 This interindividual variability in GABA level is linked to i

149 uence of GABA raises the question of whether interindividual variability in GABA reflects an overall

150 sponse is important for the understanding of interindividual variability in human pathologies.

151 genetics and review the emerging evidence of interindividual variability in humoral and cell-mediated

152 ments using human genotyped livers showed an interindividual variability in hydroxytyrosol formation

153 uals with monogenic FH, there is substantial interindividual variability in LDL-C levels and risk of

154 archical Gaussian filter model that captures interindividual variability in learning under uncertaint

155 the amygdala and accounts for virtually all interindividual variability in long-term fear memory str

156 There is marked interindividual variability in metabolism and resulting

157 at distal regulatory elements may affect the interindividual variability in microRNA expression level

158 should focus on the mechanisms and levels of interindividual variability in OA response, so that we c

159 mediated diseases are a major determinant of interindividual variability in pattern recognition recep

160 mediated diseases are a major determinant of interindividual variability in pattern-recognition recep

161 have repeatedly been shown to lead to great interindividual variability in performance.

162 However, the neuroanatomical origins of interindividual variability in reaction time (RT) remain

163 s highlight the neuroanatomical signature of interindividual variability in response speed along the

164 However, significant interindividual variability in risk suggests a role for

165 The human cochlea shows considerable interindividual variability in size and morphology.

166 on within each eye; however, it showed large interindividual variability in size, shape, location, an

167 Here, we examine interindividual variability in skin MC responses to Fcep

168 n estimated internal doses of SVOCs, and (2) interindividual variability in such exposure can result

169 Interindividual variability in susceptibility remains po

170 Despite high interindividual variability in terms of relative tissue

171 be thought of as a connectome disease, with interindividual variability in the brain's adaptation to

172 modest but independent contributions to the interindividual variability in the capacity to oxidize f

173 Interindividual variability in the dose-dependent associ

174 e disorders are common, in large part due to interindividual variability in the genetic causes and ph

175 albeit with a collapsed nostril and a larger interindividual variability in the gyrus.

176 y underline the importance of accounting for interindividual variability in the investigation of func

177 contribution of a self-selected diet to the interindividual variability in the MFO requires further

178 A total of 44.4% of the interindividual variability in the MFO was explained by

179 ain activities together accounted for 81% of interindividual variability in the modulation of movemen

180 copic resolution and observed an astonishing interindividual variability in the shape.

181 We here examined the interindividual variability in the vmPFC sulcal morpholo

182 egulation by microRNA (miRNA) contributes to interindividual variability in UGT2B expression and is a

183 Thus, interindividual variability in ventral striatal presynap

184 K; however, there is still large unexplained interindividual variability in vitamin K status.

185 Interindividual variability in weight loss and metabolic

186 Evaluation of interindividual variability is a challenging step in ris

187 Capturing interindividual variability is essential to increase the

188 xpression in the human brain and showed that interindividual variability is less pronounced than vari

189 This interindividual variability may be an important factor f

190 study provides a complete description of the interindividual variability of anatomical morphology of

191 We characterized interindividual variability of circRNA expression in the

192 is is a strong clinical need given the large interindividual variability of DKD progression.

193 Analysis of scedasticity showed that interindividual variability of DNA methylation increased

194 ns of pharmacokinetic profiles, resulting in interindividual variability of drug toxicity and/or effi

195 rm infants; in addition, intraindividual and interindividual variability of human milk protein and en

196 genetics, and cellular heterogeneity on the interindividual variability of immune responses and cons

197 disease, and understanding genetic causes of interindividual variability of immune responses is vital

198 Our study provides evidence that the interindividual variability of mood/apathy, attention/me

199 f this meta-analysis was to evaluate: 1) the interindividual variability of reductions in low-density

200 Interindividual variability of striatal D2/3R (VR = 1.26

201 yed meta-analysis of variance to investigate interindividual variability of striatal dopaminergic fun

202 population-specific equations showed a lower interindividual variability of the bias than the other e

203 al level, for example, in differences in the interindividual variability of these brain volumes relat

204 However, knowledge is still lacking on interindividual variability of these communities and the

205 participants developed algorithms to predict interindividual variability of toxic response from genom

206 In these data-based models, interindividual variability was quantified by a key para

207 geneity of the brain Li distribution and its interindividual variability, as well as the strong corre

208 eat promise, its signal exhibits substantial interindividual variability, which needs to be accounted

209 after disease onset and demonstrates little interindividual variability.

210 e assignment of connections to areas despite interindividual variability.

211 lower maximum decrease of TXB2, with marked interindividual variability.

212 (GluA2:GluN1; GluN2A:GluN2B), and determined interindividual variability.

213 ied young childhood as a stage of heightened interindividual variability.

214 s yields unsatisfactory results due to great interindividual variability.

215 thy donors, with minimal intraindividual and interindividual variability.

216 smaller than the differences that are due to interindividual variability.

217 nt a complex ecosystem with a high degree of interindividual variability.

218 9 mm, and histologic composition showed high interindividual variability.

219 ypical sensory processing, with considerable interindividual variability.

220 to verify the microarray results and assess interindividual variability.

221 bolism-toxicity interactions and quantifying interindividual variability.

222 ) compared with standard stems but with high interindividual variability.

223 titutions and controlled for most factors of interindividual variability.

224 d linearly with n-3 PUFA dose and showed low interindividual variance (r2 > 0.95).

225 Moreover, choline levels explained interindividual variance in perseveration over and above

226 ogether, these findings explained 55% of the interindividual variance in WM capacity when combined wi

227 e tested whether this variability depends on interindividual variance or the type of motor task inves

228 ue to the different tasks investigated or to interindividual variance.

229 Interindividual variant Creutzfeldt-Jakob disease (vCJD)

230 entifies 9926 correlated regions of systemic interindividual variation (CoRSIVs).

231 P profiles with 8 SNPs demonstrated greatest interindividual variation and high intraindividual consi

232 ithin individuals but exhibited considerable interindividual variation and was influenced by T1D-asso

233 ded to better define the dose effect and its interindividual variation for carotenoids and fat-solubl

234 There is interindividual variation in arsenic metabolism efficien

235 However, continuous interindividual variation in ASD suggests that there is

236 tween 1.7% (Ang-2) and 11.2% (sTie-2) of the interindividual variation in biomarker levels.

237 brain calcification cases, we describe high interindividual variation in calcification load in Pdgfb

238 n the same GMFCS level, we found substantial interindividual variation in development for mobility, a

239 The interindividual variation in development within GMFCS le

240 We utilized interindividual variation in developmental rate among th

241 0 GL-contributing food groups explained less interindividual variation in dietary GI (R(2): 0.376 com

242 We demonstrate systemic and stochastic interindividual variation in DNA methylation at the VTRN

243 gorithm to identify genomic regions at which interindividual variation in DNA methylation is consiste

244 ed screen for human genomic regions at which interindividual variation in DNA methylation is not tiss

245 At exceptional genomic regions, interindividual variation in DNA methylation occurs syst

246 al role of noncoding RNAs as determinants of interindividual variation in drug response.

247 istic tractography indicated that 10%-20% of interindividual variation in emotional regulation abilit

248 Genetic variation contributes to the interindividual variation in growth factor levels and ex

249 methods confound the ability to investigate interindividual variation in gut microbiome profiles.

250 ties, like those of humans, exhibited higher interindividual variation in infancy versus later in lif

251 Coupled with previous work showing that the interindividual variation in LTL across newborns is as w

252 regulation by smoking/nicotine will increase interindividual variation in lung CYP2A levels, which ma

253 ubstance in the world and presents with wide interindividual variation in metabolism.

254 tic concept was validated by determining the interindividual variation in one of the four model react

255 r results reveal common alleles that explain interindividual variation in pathogen sensing and provid

256 , LDLR and PCSK7), which in turn may promote interindividual variation in phenotypes.

257 There is heritability to interindividual variation in platelet count, and better

258 There is considerable interindividual variation in platelet FcgammaRIIA activa

259 A large proportion of interindividual variation in recombination rate is herit

260 FAs, the likelihood of clinically meaningful interindividual variation in response to SFA reduction,

261 at single-neuron responses were sensitive to interindividual variation in scallop sequences, raising

262 cally highlighting the fornix as a source of interindividual variation in scene discrimination in hum

263 There was extensive interindividual variation in selection, with different d

264 y aging population, but the genetic basis of interindividual variation in senescence remains largely

265 al strong heritable genetic contributions to interindividual variation in song tempo but that the deg

266 xplaining an additional 1.4% and 2.0% of the interindividual variation in systolic and diastolic BP,

267 y and social network factors jointly explain interindividual variation in tendency to interact with h

268 nucleolar associations are buffered against interindividual variation in the distribution of rDNA.

269 Interindividual variation in the dorsal striatal compone

270 an association in a rodent species with high interindividual variation in the number of expressed MHC

271 factors contributing to the well-recognized interindividual variation in the progression and outcome

272 ndividualizing the current amplitude reduced interindividual variation in the stimulation focality by

273 investigated this heterogeneity by defining interindividual variation in the transcriptome of patien

274 The DO mice display interindividual variation in toxicity response and, as s

275 SSI and age had a significant effect on the interindividual variation in VD.

276 Interindividual variation is only partly accounted for b

277 Interindividual variation of band 3 and CD45 was low, 6

278 Interindividual variation was much greater than that att

279 sed a similar increase in DOPAC/DA ratio but interindividual variation was significantly reduced.

280 CD protein concentration and calculation of interindividual variation which is difficult by other me

281 , followed by defocus, interscan difference, interindividual variation, and left-right eye difference

282 obial alpha-diversity, composition, density, interindividual variation, and within-individual change

283 Although there was some interindividual variation, in many patients suppression

284 We report a high level of interindividual variation, with low longitudinal variati

285 hypotheses about mechanisms contributing to interindividual variation.

286 ained in the pancreas of the HVs, with large interindividual variation.

287 human microbiome studies is limited by high interindividual variation.

288 Neuroimaging investigations have revealed interindividual variations in anatomy, metabolism, activ

289 score, and change in BMI z-score] related to interindividual variations in caloric compensation abili

290 mine the contributions of the food groups to interindividual variations in dietary GI and GL.Overall,

291 ays an important role in accounting for such interindividual variations in drug response.

292 Data were also obtained on interindividual variations in flavanone bioavailability.

293 However, these cells display wide intra- and interindividual variations in gene expression, which mak

294 the dominant role that diet plays in shaping interindividual variations in host-associated microbial

295 and circuitry, of relevance to understanding interindividual variations in regulation of responses to

296 We find that, even though interindividual variations in specific cell population f

297 the A118G OPRM1 polymorphism contributes to interindividual variations in the function of neurotrans

298 Mammals exhibit marked interindividual variations in their gut microbiota, but

299 irments with a personalised approach, taking interindividual variations into account, will further im

300 and successfully estimated and showed large interindividual variations of concentrations (2-3 orders