ライフサイエンスコーパス: intermediary

1 can manifest without a lymph node metastatic intermediary.

2 ized binding to methylated chromatin without intermediary.

3 of principal neuronal activity via astrocyte intermediaries.

4 utes by quantitatively drawing off TCA cycle intermediaries.

5 e controlled indirectly, via transcriptional intermediaries.

6 s of these networks depend on the choices of intermediaries.

7 ream acetyl coenzyme A formation module; the intermediary acetyl-CoA activation module; and the downs

8 ogenomics further suggests that oxidation of intermediary acetyl-CoA to CO(2) occurs through the oxid

9 ibiting phosphorylation of the intracellular intermediaries AKT and extracellular signal-regulated ki

10 household contacts of controls (25.2%), and intermediary among extra-household tuberculosis contacts

11 owth by introducing the CTC population as an intermediary and assuming dependency.

12 ith STIM1 and ORAI1 through protein or lipid intermediaries, and are favorably positioned to coordina

13 ion, environmental perturbations, regulatory intermediaries, and molecular sequelae that ultimately l

14 therapies targeting 6 PAH-specific molecular intermediaries are used clinically.

15 ZnOSi(L')(OC=As) 5, essentially trapping the intermediary arsinidene 3 with liberated CO following in

16 t complexes (COA complexes) to form the Cox1 intermediary assembly module.

17 ntiate in the bone marrow through progenitor intermediaries before entering the blood, in a process t

18 h Domain Criteria position these deficits as intermediaries between molecular and cellular mechanisms

19 that emphasize the role of astrocytes as key intermediaries between peripheral immune events, neurona

20 ex has the requisite dynamics to serve as an intermediary between brain regions generating different

21 As an intermediary between cells and scaffolding biomaterials,

22 These findings identify Padi2 as a potential intermediary between early calcium signaling and subsequ

23 blasts to test the hypothesis that TG2 is an intermediary between enhanced tissue glycolysis and fibr

24 roach to examine behavioural variation as an intermediary between environmental variation and energet

25 d phosphatase receptor (PTPRF) as a putative intermediary between extracellular glycosylated CSPGs an

26 the coding genome and provides an efficient intermediary between functional genomics data and revers

27 ism-not brain structure-that is the critical intermediary between genetics and the childhood risk to

28 By considering gene expression as the intermediary between genotype and disease phenotype, exp

29 organizing, self-replicating, auto-catalytic intermediary between macromolecules and cellular life.

30 ogenesis and suggest that macrophages are an intermediary between neovascularization and organ archit

31 We propose that this formation represents an intermediary between the cluster flocks of starlings and

32 Viral structural proteins form the critical intermediary between viral infection cycles within and b

33 ection results in reduced levels of upstream intermediaries (called IKKs) that are needed for NF-kapp

34 nism-outcome propositions that postulate how intermediaries can contribute to promoting best practice

35 at certain individuals, collectively termed 'intermediaries', can contribute to implementation proces

36 This transformation probably involves an intermediary carbocation, based on observations with add

37 It encodes and expresses a complete intermediary carbon metabolism and enhanced carbon fixat

38 large variety of functions, such as being an intermediary carrier of the genetic information, transla

39 In particular, TXNIP, a key inflammasome intermediary, causes assembly of the NLRP3 inflammasome,

40 Rac1-GTPases serve as intermediary cellular switches, which conduct transient

41 derived the flow of resources from source to intermediary channel to recipient.

42 urine neutrophils led to a strongly impaired intermediary chemotaxis after CXCR2 activation which is

43 els play a pronounced role in CXCR2-mediated intermediary chemotaxis, whereas N-formyl-methionine-leu

44 ific role of TRPC6 channels in CXCR2-induced intermediary chemotaxis.

45 ral and hydrodynamic information revealed an intermediary compactness of the protein between globular

46 eport that D2 is a cargo protein in ER Golgi intermediary compartment (ERGIC) vesicles, recycling bet

47 oplasmic reticulum (ER) through the ER-Golgi intermediary compartment directly to recycling endosomes

48 s of PaaF and PaaG are adapted to accept the intermediary components of the Paa pathway, different fr

49 Finally, the same intermediaries control the signaling response in tissues

50 and implements a desired limb trajectory, an intermediary control process between the behavioral goal

51 ness centrality measurements to identify key intermediary countries.

52 In contrast to its role at organ boundaries, intermediary CUP activity leads to growth promotion rath

53 Under limiting IsdC conditions, the IsdC intermediary cycles between heme-free and heme-containin

54 diffusion, use RNA cleavage to recover from intermediary depths, and are unable to recover from exte

55 but preceding swimming, making it a discrete intermediary developmental behavior.

56 For 2a (R = TMS), a 1,3-silyl shift gave an intermediary disilene, which was trapped as unique NHC-d

57 wall of cochlear outer hair cells and had an intermediary distribution (both cytoplasmic and cortical

58 d heterogeneous nuclear ribonucleoprotein as intermediary effectors in this feedback loop was interro

59 tosis, and microglial activation, as well as intermediary effects on cytokine upregulation.

60 hominin hunting behaviours because of their intermediary effects on prey detection performance.

61 ors with the biomaterial during printing, or intermediary encapsulation of growth factors in delivery

62 tients based on baseline characteristics and intermediary events.

63 erum antibodies to oral bacteria might be an intermediary explanatory variable linking the associatio

64 Intermediary expression of CUP homologs is also observed

65 the absence of Foxo1, insulin signals via an intermediary extrahepatic tissue to regulate liver gluco

66 e sumoylation process by using transcription intermediary factor (TIF)-1gamma as a substrate.

67 E3 ubiquitin-protein ligase transcriptional intermediary factor 1 gamma (TIF1gamma) from binding SMA

68 s have been developed for anti-transcription intermediary factor 1 gamma, anti-MDA5 and anti-nuclear

69 c TH cells and identified that transcription intermediary factor 1 regulator-alpha (Tif1alpha)/tripar

70 , 2.01-119.90), whereas anti-transcriptional intermediary factor 1-gamma antibodies were protective (

71 d negatively associated with transcriptional intermediary factor 1-gamma antibodies.

72 that 4-mo-old mice deleted for transcription intermediary factor 1gamma (Tif1gamma) in HSCs developed

73 Transcriptional intermediary factor 1gamma (TIF1gamma; alias, TRIM33/RFG

74 e transcriptional regulator, transcriptional intermediary factor 1gamma, TIF1gamma, as an APC/C-inter

75 t, but instead statistically depended on the intermediary factor of diminished NREM SWA.

76 ed an essential role for the transcriptional intermediary factor TIF1gamma in erythropoiesis by regul

77 ggesting that GCs suppress indirectly via an intermediary factor.

78 ng 28 (TRIM28; also known as transcriptional intermediary factor1beta and Kruppel-associated box-asso

79 Manipulation of the M factor and possible intermediary factors may result in female-to-male conver

80 anthropometric measurements, adjustment for intermediary factors, and exclusion of early deaths or p

81 Deeper understanding of the anatomical intermediaries for disease and other complex genetic tra

82 rates play a myriad of critical roles as key intermediaries for energy storage, cell wall constituent

83 harmacy benefit managers (PBMs), third-party intermediaries for various types of employers and govern

84 ncy in vivo, and BDNF is a common downstream intermediary for environmental factors that potentiate a

85 l STAT3 activation as the crucial signalling intermediary for TLR4-induced glycolysis, macrophage met

86 ependent (per)oxidase reaction involving the intermediary formation of stable cysteine sulfenates.

87 We find strong evidence that intermediaries foster more varied online news diets.

88 the transporter legacy of prestin, and this intermediary gateway, which shuttles anion-bound molecul

89 These orbital interactions involve the SOMO (intermediary generated from the stannyl radical addition

90 demographic characteristics, depression) and intermediary (health behaviors, health conditions) varia

91 ction of participants and increases in these intermediary hormones.

92 swine, and swine have been postulated as an intermediary host for the emergence of pandemic strains.

93 ase coupled cleavage (TREC) with yeast as an intermediary host for the genome editing.

94 dence suggests that dromedary camels are the intermediary host for the Middle East respiratory syndro

95 An intermediary IE prevalence was found with Sanginosus 4.8

96 These findings implicate miRs as intermediaries in aldosterone signaling in principal cel

97 Findings offer a new lens on the role of intermediaries in bridging the evidence to practice gap.

98 A20 captures polyubiquitinated signaling intermediaries in insoluble aggresomes, thus reducing th

99 im of this study was to evaluate the role of intermediaries in promoting infection prevention, and pr

100 geted mainly onto tufted cells, which act as intermediaries in the excitation between olfactory senso

101 We propose instead that EpsW is an intermediary in a multistep phosphorelay that regulates

102 either a common source of infection or as an intermediary in a transmission chain for hosts infected

103 of renal proximal tubule IL-11 is a critical intermediary in A1 adenosine receptor-mediated renal pro

104 VFAs are identified as a key intermediary in anaerobic digestion, hence their accumul

105 aB and stress kinase pathways and thus a key intermediary in cellular survival.

106 rapies aimed at targeting its function as an intermediary in EGFR, MAPK and mTOR activation.

107 Pyruvate is a key intermediary in energy metabolism and can exert antioxid

108 zation of amorphous calcium carbonate, a key intermediary in synthetic, biological and environmental

109 d prostaglandin E2 has been implicated as an intermediary in the effects of UV radiation on BM cells.

110 the T4P assembly ATPase PilB functions as an intermediary in the EPS regulatory pathway composed of t

111 We further show that MAP3K2 is an intermediary in the signaling pathways that initiate lyt

112 ome may represent a critical, but unexplored intermediary in the snail-schistosome interaction as hem

113 Moreover, p53 is an intermediary in this regulation, as p38delta expression

114 absence of homogentisate 1,2-dioxygenase the intermediary in tyrosine catabolism homogentisate accumu

115 osynthesis involves glutathionylation of the intermediary indole-3-cyanohydrin, which is synthesized

116 These intermediaries initiate signaling cascades that promote

117 s conformational change through a network of intermediary interactions.

118 indirect relationship with an algal biomass intermediary is plausible under some circumstances.

119 de is mediated by Hpo/Mst acting through the intermediary kinase Wts/Lats to phosphorylate the transc

120 d an ordered adhesive/antiadhesive composite intermediary layer between the medical tape backing and

121 Particular styles and approaches used by intermediaries led to individual staff feeling personall

122 have a higher predominance in countries with intermediary levels of vaccine coverage.

123 a-induced pyridinoline (PYR) cross-links via intermediaries like LOX.

124 ole invasion (PTVI) pathway may represent an intermediary link between the endocytic and the penetrat

125 NA oligonucleotides using streptavidin as an intermediary linker.

126 n be established when paraphyly exists, (ii) intermediary links can be excluded when multiple lineage

127 o infer, and that the existence of unsampled intermediary links or common sources can never be exclud

128 ection of transmission and whether unsampled intermediary links or common sources existed make very d

129 tle is known about the metabolic fate of the intermediary long-chain (LC) n-3 polyunsaturated fatty a

130 te tea exposure assessment, and include both intermediary markers of risk as well as morbidity and mo

131 o many neurodegenerative conditions, but the intermediary mechanism is unclear.

132 that individual heterogeneity provides a key intermediary mechanism with broad consequences for socia

133 isk factor for late-life depression, yet the intermediary mechanisms are not known.

134 ests that additional signalling molecules or intermediary mechanisms must be involved in the actual i

135 ively extrahepatic process, disrupts hepatic intermediary metabolic homeostasis after high fat mother

136 Moreover, the intermediary metabolic pathway of de novo lipogenesis, w

137 lism are genetic conditions that can disrupt intermediary metabolic pathways and cause defective abso

138 Nearly all changes in genes related to intermediary metabolic regulation were replicated in cul

139 tional normalization of broadly dysregulated intermediary metabolic, glutathione, cell defense, DNA,

140 y and inflammation), 2 biomarkers related to intermediary metabolism and adipocyte biology (fatty aci

141 constituents, chemotaxis/motility machinery, intermediary metabolism and cellular physiology.

142 Numerous connections between products of intermediary metabolism and chromatin proteins have rece

143 In this review, the basics of intermediary metabolism and core metabolic pathways will

144 of the glycolytic pathway and other parts of intermediary metabolism and hence are called glycosomes.

145 ria play a central role in the regulation of intermediary metabolism and maintenance of normoglycemia

146 yl-CoA affects histone acetylation and links intermediary metabolism and transcriptional regulation.

147 er formalism describes key pathways of tumor intermediary metabolism and yields dynamic curves for po

148 m allows one to define essential pathways of intermediary metabolism as well metabolic vulnerabilitie

149 uraemic metabolites originate not only from intermediary metabolism but also from gut microbial meta

150 formation about a whole range of pathways of intermediary metabolism can help to identify biomarkers

151 )H/(13)C metabolic flux analysis to quantify intermediary metabolism fluxes in both sedentary and tre

152 Intermediary metabolism generates substrates for chromat

153 o mitochondria represents a critical step in intermediary metabolism impacting numerous diseases.

154 Intermediary metabolism in cancer cells is regulated by

155 These findings warrant future studies of intermediary metabolism in patients treated with beta-la

156 analysis provides quantitative insights into intermediary metabolism in PDK-knockout mice.

157 molog 1 (LRH-1) is an important regulator of intermediary metabolism in the liver, but its role in re

158 w metabolic imaging technique that can probe intermediary metabolism nondestructively.

159 , implicating dysregulation of CoA-dependent intermediary metabolism rather than respiratory chain de

160 rturbations in amino acid, carbohydrate, and intermediary metabolism that were only transiently ameli

161 triking pattern of global underexpression of intermediary metabolism transcripts in BPH.

162 wall structure/function, cell division, and intermediary metabolism were also evident.

163 rohormonal regulators of mineral metabolism, intermediary metabolism, and biomarkers of myocardial in

164 gene regulation, DNA damage, ion transport, intermediary metabolism, and mitochondrial function.

165 ternate substrates for energy generation and intermediary metabolism, and remodeling of the cell enve

166 recent studies and the relationships between intermediary metabolism, antibody production, and lifesp

167 in response, has long been known to regulate intermediary metabolism, but the details are poorly work

168 the obvious read out of hypoxia, effects on intermediary metabolism, has not been investigated.

169 egradation of the targeted RNA, altering RNA intermediary metabolism, or disrupting function of the R

170 tabolism (OCM), an integral part of cellular intermediary metabolism, produces a number of one-carbon

171 and post-translational network that affects intermediary metabolism, ribosomal biogenesis, and prote

172 sduces the activity of eNOS in reprogramming intermediary metabolism, thereby protecting kidneys agai

173 purines and pyrimidine biosynthesis, central intermediary metabolism, transport and binding.

174 key link between inflammatory processes and intermediary metabolism.

175 ed from metabolites that are at key nodes of intermediary metabolism.

176 triggered by sulfhydration of key enzymes in intermediary metabolism.

177 lified by adaptive changes in the enzymes of intermediary metabolism.

178 or encephalopathies associated with impaired intermediary metabolism.

179 cancers with mutations of genes involved in intermediary metabolism.

180 otype provides productive insight into human intermediary metabolism.

181 cial steering function for the regulation of intermediary metabolism.

182 f ATP, and are involved in many reactions of intermediary metabolism.

183 essential cofactors for enzymes required in intermediary metabolism.

184 refore assessed the role of LRH-1 in hepatic intermediary metabolism.

185 odel indicates that CL is also essential for intermediary metabolism.

186 e intrinsic nutritional value of a meal with intermediary metabolism.

187 line INS 832/13 and rat islets by inhibiting intermediary metabolism.

188 enzymes that participate in key pathways in intermediary metabolism: carbamoylphosphate synthetase 1

189 ar Cell, Weinert et al. demonstrate that the intermediary metabolite acetyl-phosphate is an important

190 he spatial and temporal partitioning of this intermediary metabolite is intrinsic to understanding th

191 he important role played by cross-feeding of intermediary metabolites (in particular lactate, succina

192 ignaling pathway, but little is known on how intermediary metabolites are integrated as metabolic sig

193 r machinery that controls the homeostasis of intermediary metabolites in mitochondria.

194 While intermediary metabolites serve as co-factors for histone

195 ope tracing of glycolytic and tricyclic acid intermediary metabolites.

196 upregulated multiple pyrimidine biosynthesis intermediary metabolites.

197 including glucose, amino acids, and various intermediary metabolites.

198 e migrant, the rough-legged buzzard, with an intermediary migration pattern, and the peregrine falcon

199 d to guide the design and development of new intermediary models in healthcare, to promote best pract

200 otably, glutamine appears to be an important intermediary molecule between the neuronal and astrocyti

201 Here, mRNA serves as a transient intermediary molecule in the information network, whilst

202 ligand (e.g., triflate) and formation of an intermediary molybdacyclobutane trans to the NHC.

203 n poorly understood, partly due to a lack of intermediary monogenic human phenotypes.

204 In addition, an intermediary monomer, bis(2-hydroxyethyl)terephthalate,

205 tion and thereby influences the formation of intermediary MR products as well as radicals.

206 neighbors from indirect junctions involving intermediary, multiply connected cells.

207 a catalytic cycle involving formation of an intermediary NAD(+)-bound complex.

208 We achieve this by using an intermediary nanomechanical resonator that converts the

209 -cell responses both directly and through an intermediary nonlymphoid cell population.

210 te and dynamic time course data on signaling intermediaries, normally and in diabetes, we developed a

211 tart of the reaction (G-protein.GEF.GDP), an intermediary nucleotide-free binary complex (G-protein.G

212 lators and antioxidants, including important intermediaries of the tricarboxylic acid (TCA) cycle, am

213 boxamide riboside 5'-monophosphate (ZMP), an intermediary of de novo purine biosynthetic pathway, and

214 ect of proline was mimicked by glutamate, an intermediary of proline metabolism.

215 Succinate, in addition to its role as an intermediary of the citric acid cycle, acts as an alarmi

216 The structure and properties of the intermediary oligomers have been difficult to study due

217 sulate the effects of social media and other intermediaries on news exposure.

218 d discusses the impact of lead firms and key intermediaries on smallholders in different chain situat

219 en orthogonal DNA enantiomers via an achiral intermediary, opening the door for "heterochiral" DNA na

220 s of very similar frequency, but by using an intermediary optical mode, non-degenerate modes can inte

221 tivity or by inhibiting osteoclast signaling intermediaries or through negative feedback loops.

222 yotic intermediary processes and prokaryotic intermediary or biodegradative metabolism.

223 Using a metabolomics platform that analyzes intermediary organic acids, purines, pyrimidines, and ot

224 ) and secondarily on stunting (HAZ < -2) and intermediary outcomes including household's food insecur

225 phils in the healthy oral cavity occur in an intermediary parainflammatory state that allows them to

226 he viral-induced autophagic machinery via an intermediary partner, TUFM.

227 occur through the activation of alternative intermediary pathways.

228 y attenuated, while the double mutant has an intermediary phenotype.

229 tory responses and levels of the coagulation intermediary plasminogen activator inhibitor 1 in three

230 Here we provide an intermediary platform between HTS and mice by adapting m

231 Regulating intermediary polysulfide dissolution by understanding th

232 10 min) transformed jarosite to a green rust intermediary, prior to the subsequent precipitation of g

233 for triuret hydrolase in certain eukaryotic intermediary processes and prokaryotic intermediary or b

234 The intermediary processes in the assembly of MCC are not su

235 e/paracrine C3ar1/C5ar1 signaling as crucial intermediary processes that link TLR stimulation to DC m

236 The concept of a long, intermediary, prodromal phase between the first appearan

237 and strongly basic conditions to convert the intermediary product 5,6-dihydrouridine-6-sulfonate (dhU

238 Analysis of intermediary products (neutralized, bleached and deodori

239 t understanding exactly what happens and how intermediaries promote best practice is unclear.

240 ugh an endochondral process with a cartilage intermediary prompting the hypothesis that hypoxic signa

241 es, and can interact with membranes both via intermediary proteins and directly via its microtubule-b

242 To identify intermediary proteins, we isolated EBER2-PAX5-containing

243 ation, obviating any requirement for soluble intermediary proteins.

244 anin and madanin-1, without the need for any intermediary purification.

245 EGCG) inhibited formation of highly reactive intermediary radicals appearing during the Maillard reac

246 to be more efficient than EC as inhibitor of intermediary radicals during the MR.

247 ective differentiation from CD103(-)CD11b(+) intermediaries, rather than an isolated loss of CD103 ex

248 well as that whose translocation requires an intermediary receptor.

249 d and the low-energy azo pi* orbitals in the intermediary redox state and additional stabilization of

250 CUP is activated by dorsoventral genes in an intermediary region of the corolla.

251 ndirectly increases ltxA expression, but the intermediary regulator is unknown.

252 We propose that MgrA can serve as an intermediary regulator through which agr exerts its regu

253 reviously unidentified structure type has an intermediary relationship between MB2 and MB12 type bori

254 embryo via the placenta, the maternal-fetal intermediary responsible for maintaining intrauterine ho

255 anism for bone loss with VSG, G-CSF plays an intermediary role for effects of VSG on the bone marrow

256 MBPs thus play a key intermediary role in gene regulation for both normal and

257 est that the endocannabinoid system plays an intermediary role in regulating rapid glucocorticoid eff

258 Bifurcated and intermediary salt-bridge and hydrogen-bond interactions

259 ism, but does not require nitric oxide as an intermediary signal.

260 To accomplish this, GPCRs first bind to an intermediary signaling protein, such as G protein or arr

261 d by a combined regulation of MET levels and intermediary signaling through mitogen-activated protein

262 tact is reversed after mating, indicating an intermediary situation between naive and mating conditio

263 The rings of intermediary size served as generalization stimuli, crea

264 The intermediary slow transition probably relates to the tra

265 protein expression of BMPR-II, the signaling intermediary Smad1, and the downstream genes, inhibitors

266 ype I and II BMP receptors and the signaling intermediaries (Smads), we demonstrated a key role for A

267 simple on-farm interventions like RBF can be intermediary solutions for communities in urbanizing wat

268 here can also be indirect effects through an intermediary species, such as in host-plant interactions

269 dence on whether these polymorphisms predict intermediary stage outcomes such as cognitive changes in

270 tional neurons while bypassing any stem cell intermediary stages.

271 revious computational results implicating an intermediary state between formation of the first and se

272 ancers but of uncertain origin, served as an intermediary step in MV reversion to normal microvessels

273 Moreover, it can be used as an intermediary step in protein structure predictions eithe

274 They can be used as an intermediary step in protein structure predictions.

275 the role of contrast sensitivity (CS) as an intermediary step in the causal pathway between macular

276 xes with high on and off rates, an important intermediary step in the HLA-I maturation process.

277 y (CT) data in sinogram-space, bypassing the intermediary step of image reconstruction.

278 5D may be involved in modulating DMP-1 in an intermediary step.

279 Finally, minimal use of intermediary steps as well as direct, late stage C-7 hyd

280 a high-resolution imaging assay to visualize intermediary steps of the lateral to end-on conversion p

281 The intermediary steps of this process are unclear, in parti

282 e from evolutionary processes, through which intermediary steps these arise, and whether they embody

283 ontent, were vacuum packing and freezing for intermediary storage times (24-32weeks) with a reported

284 mologous DNA molecules that arise as central intermediary structures during homologous recombination

285 point confirmed these elements as the likely intermediary substrates that sponsored inversion formati

286 tate via a cross-Kerr interaction induced by intermediary superconducting qubits between neighbouring

287 e strain (i.e. possible infectors) had fewer intermediaries than predicted by chance (P < 0.001), a f

288 The lithosphere acts as the intermediary that transfers the effects of mantle dynami

289 o pathway cooperate to regulate, via rosette intermediaries, the intercalation of post-mitotic neuron

290 ike motif-containing domain functions as the intermediary through which the 14-3-3 protein modulates

291 ate constants revealed the involvement of an intermediary tilted conformation E-III, which structural

292 loping new interventions/programmes that use intermediaries to plug the gap between theory and practi

293 ing our understanding about the potential of intermediaries to promote best practice.

294 d that tyrosine (Tyr or Y) 224 serves as HAT intermediary to separate the C21 radical (C21*) and Fe(I

295 od web, pelagic copepods can provide crucial intermediary transferring oil between trophic levels.

296 with computational approaches, can organize intermediary treatment targets and clinical outcomes, au

297 ocess involves modification of the signaling intermediary tumor necrosis factor receptor-associated f

298 Findings showed that the ways in which intermediaries watch over practice (their human surveill

299 the FRET relay, the QD served as a critical intermediary where (1) an excited-state Tb donor transfe

300 is high to replenish the TCA cycle with the intermediaries withdrawn for ectoines biosynthesis.