ライフサイエンスコーパス: intermediate cell

1 ation of mostly keratin 5 (KRT5)(+)/KRT14(-) intermediate cells.

2 cal to EP generation, highly expressed in SV intermediate cells.

3 notypic diversity, including a subset termed intermediate cells.

4 p in umbrella cells, and miR-142-3p in basal-intermediate cells.

5 n increase in the number of ileal goblet and intermediate cells.

6 ed independently from p63-positive basal and intermediate cells.

7 de patterning information to both dorsal and intermediate cells.

8 promote subsequent differentiation of basal/intermediate cells.

9 ough differentiation of underlying basal and intermediate cells.

10 c skin macrophage population referred to as 'intermediate' cells.

11 to progeny throughout development - first to intermediate cells, a transient proliferative suprabasal

12 ally, there was mispositioning of Paneth and intermediate cells along the crypt-to-villus unit.

13 munoreactivity in the ganglion, granule, and intermediate cell and fiber layers.

14 rations in gene expression in the underlying intermediate cells and a local loss of strial capillarie

15 d tissue visualization of ZsGreen-expressing intermediate cells and will facilitate future studies of

16 ells that express the vnd/nk2 homeobox gene, intermediate cells, and dorsal cells that express the ms

17 a tough apical plaque, one or more layers of intermediate cells, and keratin 5-expressing basal cells

18 lts led to the expansion of CK5/CK8-positive intermediate cells, and mice developed larger and more i

19 on in populations of proliferating cells and intermediate cells, and overall decreased viability.

20 annel TMEM16A, also known as ANO1, in VSMCs, intermediate cells, and pericytes eliminated CaCCs in al

21 alamic inferior lobe diffuse nucleus) and an intermediate cell- and fiber-rich region termed here the

22 These intermediate cells are predicted to result from the repr

23 jectory analyses and infection models showed intermediate cells arise from progenitor cells before bi

24 rogenitors of the ureter differentiated into intermediate cells at E14.5.

25 ce were demonstrated to be undifferentiated "intermediate" cells by lack of expression of myoepitheli

26 EM immunohistochemical analyses suggest that intermediate cells can differentiate to mature goblet ce

27 ecified cells fails and cells proliferate to intermediate cell cluster sizes.

28 on, and expression of AR3 transgene in these intermediate cells compromises prostate epithelium regen

29 type 1 diabetes included (i) an increase of 'intermediate cells' containing granules resembling those

30 Populations of alveolar intermediate cells, coupled with focal up-regulation of

31 This protocol requires intermediate cell culture and molecular biology skills,

32 yos with DNA contents around this value show intermediate cell cycle behaviors.

33 tent with a role in processing recombination intermediates, cells depleted of SLX4 are hypersensitive

34 ers at E15.5 and three cell layers at E18.5, intermediate cells differentiated into basal cells and s

35 Lineage tracing revealed that most intermediate cells directly transition to granular cells

36 inety five percent of normal superficial and intermediate cells displayed two distinct spectral patte

37 Further, we found that intermediate cells express a subset of genes in common w

38 rolling cellular plasticity through multiple intermediate cell fates and underscores the critical inv

39 es, vnd and ind, in establishing ventral and intermediate cell fates within the Drosophila CNS.

40 tinct, viable populations of radial glia and intermediate cells for in vitro analysis.

41 nd as a suppressor for prostate cancer basal intermediate cell growth and metastasis.

42 nction nor the differentiation trajectory of intermediate cells has been documented.

43 eals that extrahepatic signaling promotes an intermediate cell (IC) population in the liver, characte

44 Using the intermediate cell (IC)-specific tyrosinase promoter, und

45 provide strong evidence indicating that the intermediate cells (ICs) of the stria vascularis (StV) e

46 examined well-established umbrella and basal-intermediate cell immunohistochemical biomarkers in an i

47 isease and show genetic targeting of luminal/intermediate cells in mice drives squamous differentiati

48 Cochlear melanocytes are intermediate cells in the stria vascularis that generate

49 e cochlear epithelium and melanocyte-derived intermediate cells in the stria vascularis.

50 o S100(+), Kir4.1(+) and Dct(+) melanocytes (intermediate cells) in the developing stria vascularis,

51 bservations that the number of Ck5(+)/Ck8(+) intermediate cells is increased in AR3Tg prostates after

52 The frequency of CD4(+)8(low) intermediate cells is markedly increased in HD mice, sug

53 ted KRT8 expression (termed KRT8(+) alveolar intermediate cells (KACs) here), reduced differentiation

54 gion of the cochlear epithelium, forming the intermediate cell layer of the stria vascularis.

55 hat interacts with a collagen substratum, an intermediate cell layer, and an upper cell layer of larg

56 ing the tissue-electronics interface with an intermediate cell layer, we have demonstrated enhanced r

57 Silencing hnRNP A2/B1 decreased migration in intermediate cell line A549 and mesenchymal cell line H1

58 The multiple intermediate cell lineage states can serve as differenti

59 s after fertilization (hpf) in the posterior intermediate cell mass (ICM) and on the anterior yolk sa

60 We investigated the mechanisms of intermediate cell mass (ICM) expansion in zebrafish chor

61 plate mesoderm at tail bud stage and in the intermediate cell mass (ICM, the location of embryonic h

62 generation of embryonic erythrocytes in the intermediate cell mass and a distinct population of macr

63 'primitive' red blood cells originate in the intermediate cell mass of the trunk, a derivative of the

64 of function of these three genes causes the intermediate cell mass, callus, to be incompetent to for

65 ted levels of apoptosis, particularly in the intermediate cell mass, the site of primitive erythropoi

66 derm to their site of differentiation in the intermediate cell mass.

67 l cells with rapid cell cycles; populate the intermediate cell mass; and differentiate into erythrocy

68 ntially expressed between umbrella and basal-intermediate cells (miR-133a, miR-139-3p, miR-142-3p, mi

69 result means that key parameters such as the intermediate cell mutation rates are not individually id

70 ssion in the cochlea and was detected in the intermediate cells of the SV, in the inner phalangeal ce

71 rain, and skeletal muscle, where contractile intermediate cells or pericytes gradually replace VSMCs,

72 (BPH), there was induction of a P63-positive intermediate cell population characterized by down regul

73 cells maintain prostate homeostasis, with an intermediate cell population emerging during prostate in

74 Here we identified a rare intermediate cell population expressing luminal markers

75 wever, the identities of basal stem cell and intermediate cell population remain unclear.

76 ing revealed that Cx3cr1+ cells represent an intermediate cell population transitioning from embryoni

77 Perturbation of the IFFL leads to a new intermediate cell population with plastic and ambiguous

78 Here, we examined defined intermediate cell populations poised to becoming iPSCs b

79 ious attempts to identify surface markers of intermediate cell populations were based on the assumpti

80 the reprogramming trajectory and to uncover intermediate cell populations, gene pathways and regulat

81 iferation rates, yet with similarly expanded intermediate cell populations, indicated that the prosta

82 and characterization of live naive cells and intermediate cell populations.

83 differentiated primary tumors with expanded intermediate cell populations.

84 phite and a Ni-COO intermediate form only at intermediate cell potentials.

85 ers of transit-amplifying cells (DeltaNp63), intermediate cells (prostate stem cell antigen), and neu

86 Fate mapping, however, reveals that intermediate cells rather than K5-BCs are progenitors in

87 , increased proportions of SAE secretory and intermediate cells, reduced proportions of SAE ciliated

88 d that retinoids are critical in P cells and intermediate cells, respectively, for their specificatio

89 show that these cells, which we refer to as intermediate cells, share features of inner cells but ex

90 and oxidative phosphorylation are highest at intermediate cell sizes.

91 Both compartments are connected through an intermediate cell stage resembling actively migrating CG

92 (+) basal and Krt15(+) club cells, detect an intermediate cell state between basal and goblet cells,

93 EMT includes a complex series of intermediate cell state changes including remodeling of

94 We found that SMCs transitioned to an intermediate cell state during atherosclerosis, which wa

95 es of amnioblast differentiation revealed an intermediate cell state with enhanced surface ectoderm g

96 f single-cell scale outputs naturally reveal intermediate cell states (ICS) and ICS-regulated transit

97 tors, deciphered transcriptional changes and intermediate cell states during regeneration, and analyz

98 oss diverse trajectory topologies, even when intermediate cell states may be missing.

99 , which make it possible to observe rare and intermediate cell states that cannot be resolved at the

100 elds new insights, including profiles of two intermediate cell states, that are supported by independ

101 g regeneration, including previously unknown intermediate cell states, which we confirm experimentall

102 rtments can result in sparse sampling of key intermediate cell states.

103 ation at single-cell resolution, identifying intermediate cell states.

104 nstrate the multi-lineage potential of these intermediate cell states.

105 and mesenchymal cell types remained low but intermediate cells still gave rise to basal cells, where

106 Alternatively, intermediate cells, such as the interstitial cells of Ca

107 ostatic adult stem cells, transit amplifying/intermediate cells (TA/ICs), and luminal cells were indi

108 SMC-derived intermediate cells, termed "SEM" cells (stem cell, endot

109 s expressing intermediate levels of CD4 (CD4-intermediate cells) than in late-stage infected cells ex

110 s are derived from a malignantly transformed intermediate cell that acquires "stem-like activity" and

111 man LUAD samples were enriched with alveolar intermediate cells that displayed elevated KRT8 expressi

112 cells to TCRalpha/betamedc-Kit+ transitional intermediate cells (the c-Kit+ pathway).

113 The intermediate cells then differentiate into late DCs whic

114 apoptotic responses (A20), and induction of intermediate cell tight junction components (claudin-4).

115 ta-cells proceeds through a MafB+ MafA- Ins+ intermediate cell to MafB- MafA+ Ins+ cells.

116 transmit information by means of a chain of intermediate cells to the retinal ganglion cells, which

117 ramming towards pluripotency in human cells, intermediate cells transiently show gene expression prof

118 notypes, but their potential to characterize intermediate cell transitions has not yet been evaluated

119 ntiation in a single snapshot as a series of intermediate cell transitions.

120 ese signals promote development of an active intermediate cell type having properties between those o

121 This study reports an intermediate cell type that develops by day 6, and has t

122 This intermediate cell type will develop along the dendritic

123 A T helper 1-polarized cell type, intermediate cell type, and exhausted T helper 2-polariz

124 ansdifferentiate to Sertoli cells through an intermediate cell type, different from gonadal embryonic

125 s, which does not require making iPSCs as an intermediate cell type.

126 t clustering that can classify both pure and intermediate cell types from data on gene expression fro

127 on program, evidenced by recently discovered intermediate cell types occupying a distinct spatiotempo

128 the differentiation of dorsal cell types and intermediate cell types throughout co-operative signalin

129 sorted HSPC phenotypes while also capturing intermediate cells typically excluded by conventional ga

130 The intermediate cells underlying the umbrella cells do not

131 To enable intermediate cell visualization, we engineered by BAC tr

132 Increased numbers of Paneth, goblet, and intermediate cells were present focally in the ileum of

133 ting prostatitis and increases the number of intermediate cells, which are considered to be the cells

134 gmentation produces a population of 'undead' intermediate cells, which have the capacity to resume pr